Menaquinone
| Title | Journal |
|---|---|
| Vitamin K2, a menaquinone present in dairy products targets castration-resistant prostate cancer cell-line by activating apoptosis signaling. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20180501 |
| Biosynthesis and Regulation of Sulfomenaquinone, a Metabolite Associated with Virulence in Mycobacterium tuberculosis. | ACS infectious diseases 20161111 |
| Vitamin K2 regression aortic calcification induced by warfarin via Gas6/Axl survival pathway in rats. | European journal of pharmacology 20160905 |
| [A New Horizon in Vitamin K Research]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20160101 |
| Plasma vitamin K concentrations depend on CYP4F2 polymorphism and influence on anticoagulation in Japanese patients with warfarin therapy. | Thrombosis research 20150501 |
| Cytochrome P450-dependent catabolism of vitamin K: ω-hydroxylation catalyzed by human CYP4F2 and CYP4F11. | Biochemistry 20131119 |
| Warfarin induces cardiovascular damage in mice. | Arteriosclerosis, thrombosis, and vascular biology 20131101 |
| The synergistic antitumor activity of arsenic trioxide and vitamin K2 in HL-60 cells involves increased ROS generation and regulation of the ROS-dependent MAPK signaling pathway. | Die Pharmazie 20131001 |
| UBIAD1-mediated vitamin K2 synthesis is required for vascular endothelial cell survival and development. | Development (Cambridge, England) 20130415 |
| Vitamin E decreases extra-hepatic menaquinone-4 concentrations in rats fed menadione or phylloquinone. | Molecular nutrition & food research 20120601 |
| Structure-activity relationship of novel menaquinone-4 analogues: modification of the side chain affects their biological activities. | Journal of medicinal chemistry 20120223 |
| Prevention of bone loss in children receiving long-term glucocorticoids with calcium and alfacalcidol or menatetrenone. | Journal of pediatric endocrinology & metabolism : JPEM 20120101 |
| PROX1 suppresses vitamin K-induced transcriptional activity of Steroid and Xenobiotic Receptor. | Genes to cells : devoted to molecular & cellular mechanisms 20111101 |
| Effect of GGCX gene polymorphism on the responses of serum undercarboxylated osteocalcin and bone turnover markers after treatment with vitamin K2 (menatetrenone) among postmenopausal Thai women. | Journal of bone and mineral metabolism 20110901 |
| Synthesis of new vitamin K analogues as steroid and xenobiotic receptor (SXR) agonists: insights into the biological role of the side chain part of vitamin K. | Journal of medicinal chemistry 20110714 |
| Cesiribacter andamanensis gen. nov., sp. nov., isolated from a soil sample from a mud volcano. | International journal of systematic and evolutionary microbiology 20110701 |
| Bone cell activity responsive drug release from biodegradable apatite/collagen nano-composite cements--in vitro dissolution medium responsive vitamin K2 release. | Colloids and surfaces. B, Biointerfaces 20110701 |
| Synthesis of novel vitamin K2 analogues with modification at the ω-terminal position and their biological evaluation as potent steroid and xenobiotic receptor (SXR) agonists. | Journal of medicinal chemistry 20110623 |
| Modelling the atypical absorption of menatetrenone and the metabolism to its epoxide: effect of VKORC1 polymorphism. | Journal of clinical pharmacy and therapeutics 20110601 |
| Effects of long-term vitamin K(1) (phylloquinone) or vitamin K(2) (menaquinone-4) supplementation on body composition and serum parameters in rats. | Bone 20110501 |
| Plasma vitamin K concentration in horses supplemented with several vitamin K homologs. | Journal of animal science 20110401 |
| A comparative effectiveness study of bone density changes in women over 40 following three bone health plans containing variations of the same novel plant-sourced calcium. | International journal of medical sciences 20110101 |
| Chemoprevention of chemically-induced biliary carcinogenesis in hamsters by vitamin K2. | Hepato-gastroenterology 20110101 |
| The prevention of hip fracture with menatetrenone and risedronate plus calcium supplementation in elderly patients with Alzheimer disease: a randomized controlled trial. | The Kurume medical journal 20110101 |
| Menaquinone-4 enhances testosterone production in rats and testis-derived tumor cells. | Lipids in health and disease 20110101 |
| Intraerythrocytic stages of Plasmodium falciparum biosynthesize menaquinone. | FEBS letters 20101201 |
| Identification of UBIAD1 as a novel human menaquinone-4 biosynthetic enzyme. | Nature 20101104 |
| Age- and brain region-specific effects of dietary vitamin K on myelin sulfatides. | The Journal of nutritional biochemistry 20101101 |
| [Dementia and fracture]. | Clinical calcium 20100901 |
| Colloid formation by drugs in simulated intestinal fluid. | Journal of medicinal chemistry 20100527 |
| Structure-activity relationships in the conversion of vitamin K analogues into menaquinone-4. Substrates essential to the synthesis of menaquinone-4 in cultured human cell lines. | Bioorganic & medicinal chemistry 20100501 |
| Inhibitory effect of vitamin K(2) on interleukin-1beta-stimulated proliferation of human osteoblasts. | Biological & pharmaceutical bulletin 20100101 |
| Vitamin K promotes mineralization, osteoblast-to-osteocyte transition, and an anticatabolic phenotype by {gamma}-carboxylation-dependent and -independent mechanisms. | American journal of physiology. Cell physiology 20091201 |
| [In vivo metabolism of vitamin K: in relation to the conversion of vitamin K1 to MK-4]. | Clinical calcium 20091201 |
| Phenobarbital (PB)-induced changes in blood coagulationrelated parameters in pregnant rats, lactating rats and pups. | The Journal of toxicological sciences 20091201 |
| Prior treatment with vitamin K(2) significantly improves the efficacy of risedronate. | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20091101 |
| Enzymatic activity of the alternative complex III as a menaquinol:auracyanin oxidoreductase in the electron transfer chain of Chloroflexus aurantiacus. | FEBS letters 20091006 |
| Inhibition of matrix metalloproteinase expression by menatetrenone, a vitamin K2 analogue. | Oncology reports 20090901 |
| Vitamin K to prevent fractures in older women: systematic review and economic evaluation. | Health technology assessment (Winchester, England) 20090901 |
| Combination of vitamin K2 and angiotensin-converting enzyme inhibitor ameliorates cumulative recurrence of hepatocellular carcinoma. | Journal of hepatology 20090801 |
| Vitamin K prevents oxidative cell death by inhibiting activation of 12-lipoxygenase in developing oligodendrocytes. | Journal of neuroscience research 20090701 |
| Vitamin K treatment reduces undercarboxylated osteocalcin but does not alter bone turnover, density, or geometry in healthy postmenopausal North American women. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20090601 |
| Elucidation of the mechanism producing menaquinone-4 in osteoblastic cells. | Bioorganic & medicinal chemistry letters 20090215 |
| Short-term menatetrenone therapy increases gamma-carboxylation of osteocalcin with a moderate increase of bone turnover in postmenopausal osteoporosis: a randomized prospective study. | Journal of bone and mineral metabolism 20090101 |
| Collagen-related abnormalities, reduction in bone quality, and effects of menatetrenone in rats with a congenital ascorbic acid deficiency. | Journal of bone and mineral metabolism 20090101 |
| Vitamin K2 suppresses proliferation and motility of hepatocellular carcinoma cells by activating steroid and xenobiotic receptor. | Endocrine journal 20090101 |
| Prevention of hip fractures by exposure to sunlight and pharmacotherapy in patients with Alzheimer's disease. | Aging clinical and experimental research 20090101 |
| Effect of oxyethylene numbers on the pharmacokinetics of menatetrenone incorporated in oil-in-water lipid emulsions prepared with polyoxyethylene-polyoxypropylene block copolymers and soybean oil in rats. | Biological & pharmaceutical bulletin 20081201 |
| Vitamin E and K interactions--a 50-year-old problem. | Nutrition reviews 20081101 |
| Effect of oil-in-water lipid emulsions prepared with fish oil or soybean oil on the growth of MCF-7 cells and HepG2 cells. | The Journal of pharmacy and pharmacology 20080801 |
| Anticoagulant effect of sodium dehydroacetate (DHA-S) in rats. | Journal of applied toxicology : JAT 20080501 |
| Conversion of phylloquinone (Vitamin K1) into menaquinone-4 (Vitamin K2) in mice: two possible routes for menaquinone-4 accumulation in cerebra of mice. | The Journal of biological chemistry 20080425 |
| [Assessment of bone quality. Effects of bisphosphonates, raloxifene, alfacalcidol, and menatetrenone on bone quality: collagen cross-links, mineralization, and microdamage]. | Clinical calcium 20080301 |
| Low plasma phylloquinone concentration is associated with high incidence of vertebral fracture in Japanese women. | Journal of bone and mineral metabolism 20080101 |
| Effects of the blood coagulation vitamin K as an inhibitor of arterial calcification. | Thrombosis research 20080101 |
| Vitamin K content of foods and dietary vitamin K intake in Japanese young women. | Journal of nutritional science and vitaminology 20071201 |
| Vitamin K induces osteoblast differentiation through pregnane X receptor-mediated transcriptional control of the Msx2 gene. | Molecular and cellular biology 20071101 |
| [Vitamin K metabolism. Menaquinone-4 (MK-4) formation from ingested VK analogues and its potent relation to bone function]. | Clinical calcium 20071101 |
| Vitamin K2 induces phosphorylation of protein kinase A and expression of novel target genes in osteoblastic cells. | Journal of molecular endocrinology 20071001 |
| Simple and sensitive determination of menatetrenone and its epoxide metabolite in human plasma. | Journal of pharmaceutical and biomedical analysis 20070903 |
| Prevention of hepatocarcinogenesis with phosphatidylcholine and menaquinone-4: in vitro and in vivo experiments. | Journal of hepatology 20070701 |
| Determination of vitamin K homologues by high-performance liquid chromatography with on-line photoreactor and peroxyoxalate chemiluminescence detection. | Analytica chimica acta 20070522 |
| Menatetrenone, a vitamin K2 analogue, inhibits hepatocellular carcinoma cell growth by suppressing cyclin D1 expression through inhibition of nuclear factor kappaB activation. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070401 |
| Synergistic growth inhibition by acyclic retinoid and vitamin K2 in human hepatocellular carcinoma cells. | Cancer science 20070301 |
| [Suspicious case of epidural hematoma due to coagulopathy caused by vitamin K deficiency associated with antibiotics]. | Masui. The Japanese journal of anesthesiology 20070201 |
| Comparative uptake, metabolism, and utilization of menaquinone-4 and phylloquinone in human cultured cell lines. | Bioorganic & medicinal chemistry 20061001 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Menadione is a metabolite of oral vitamin K. | The British journal of nutrition 20060201 |
| Pleiotropic actions of vitamin K: protector of bone health and beyond? | Nutrition (Burbank, Los Angeles County, Calif.) 20060101 |
| Geranylgeranylacetone inhibits formation and function of human osteoclasts and prevents bone loss in tail-suspended rats and ovariectomized rats. | Calcified tissue international 20051201 |
| Vitamins K2, K3 and K5 exert in vivo antitumor effects on hepatocellular carcinoma by regulating the expression of G1 phase-related cell cycle molecules. | International journal of oncology 20050801 |
| The secondary electron acceptor of photosystem I in Gloeobacter violaceus PCC 7421 is menaquinone-4 that is synthesized by a unique but unknown pathway. | FEBS letters 20050704 |
| Determination of plasma Vitamin K by high-performance liquid chromatography with fluorescence detection using Vitamin K analogs as internal standards. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050225 |
| Method for the determination of vitamin K homologues in human plasma using high-performance liquid chromatography-tandem mass spectrometry. | Analytical chemistry 20050201 |
| [Therapy for ROD and measurement of the bone mass]. | Clinical calcium 20041201 |
| Effects of vitamin K2 (menatetrenone) and alendronate on bone mineral density and bone strength in rats fed a low-magnesium diet. | Bone 20041101 |
| Histochemical evaluation for the biological effect of menatetrenone on metaphyseal trabeculae of ovariectomized rats. | Bone 20041001 |
| Quinones as antimycobacterial agents. | Bioorganic & medicinal chemistry 20040915 |
| Prolonged circulation of menatetrenone by emulsions with hydrogenated castor oils in rats. | Journal of controlled release : official journal of the Controlled Release Society 20040220 |
| Impaired gamma carboxylation of osteocalcin in elderly women with type II diabetes mellitus: relationship between increase in undercarboxylated osteocalcin levels and low bone mineral density. | Journal of bone and mineral metabolism 20040101 |
| High serum levels of menatetrenone in male patients with ossification of the posterior longitudinal ligament. | Spine 20030815 |
| Novel role of vitamin k in preventing oxidative injury to developing oligodendrocytes and neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030702 |
| Effects of menatetrenone on the bone and serum levels of vitamin K2 (menaquinone derivatives) in osteopenia induced by phenytoin in growing rats. | Nutrition (Burbank, Los Angeles County, Calif.) 20030501 |
| Effect of particle size on the pharmacokinetics of menatetrenone incorporated in O/W lipid emulsions prepared with hydrogenated castor oils and soybean oil in rats. | Journal of drug targeting 20030501 |
| Vitamin K stimulates osteoblastogenesis and inhibits osteoclastogenesis in human bone marrow cell culture. | The Journal of endocrinology 20030301 |
| Effect of oxyethylene moieties in hydrogenated castor oil on the pharmacokinetics of menatetrenone incorporated in O/W lipid emulsions prepared with hydrogenated castor oil and soybean oil in rats. | Journal of drug targeting 20030101 |
| Tissue-specific utilization of menaquinone-4 results in the prevention of arterial calcification in warfarin-treated rats. | Journal of vascular research 20030101 |
| Effect of eicosapentaenoic acid in patients with refractory myelodysplastic syndrome. | American journal of hematology 20021201 |
| [Pharmacotherapy of osteoporosis]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20021201 |
| A calcium-deficient diet caused decreased bone mineral density and secondary elevation of estrogen in aged male rats-effect of menatetrenone and elcatonin. | Metabolism: clinical and experimental 20021001 |
| Effect of oxyethylene moiety in polyoxyethylene sorbitan esters on the pharmacokinetics of menatetrenone incorporated in O/W lipid emulsions prepared with polyoxyethylene sorbitan esters and soybean oil in rats. | The Journal of pharmacy and pharmacology 20021001 |
| A comparison of alfacalcidol and menatetrenone for the treatment of bone loss in an ovariectomized rat model of osteoporosis. | Calcified tissue international 20020701 |
| Vitamin K supplementation does not affect ovariectomy-induced bone loss in rats. | Bone 20020601 |
| Difference in the metabolism of vitamin K between liver and bone in vitamin K-deficient rats. | The British journal of nutrition 20020401 |
| [Comparative analyses on osteoporosis guidelines in Japan, EU and USA]. | Nihon rinsho. Japanese journal of clinical medicine 20020301 |
| Menaquinone-4 in breast milk is derived from dietary phylloquinone. | The British journal of nutrition 20020301 |
| Differential lipoprotein transport pathways of K-vitamins in healthy subjects. | Biochimica et biophysica acta 20020215 |
| Efficacy and safety of Menatetrenone-4 postmenopausal Thai women. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20011001 |
| Inverse correlation between the changes of lumbar bone mineral density and serum undercarboxylated osteocalcin after vitamin K2 (menatetrenone) treatment in children treated with glucocorticoid and alfacalcidol. | Endocrine journal 20010201 |
| Supplementation of rats with a lutein mixture preserved with vitamin E reduces tissue phylloquinone and menaquinone-4. | International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 20010101 |
| Effect of menatetrenone on bone mineral density and incidence of vertebral fractures in postmenopausal women with osteoporosis: a comparison with the effect of etidronate. | Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20010101 |
| Vitamin K(2) inhibits adipogenesis, osteoclastogenesis, and ODF/RANK ligand expression in murine bone marrow cell cultures. | Bone 20001201 |
| Comparative effects of vitamin K2 and vitamin E on experimental arteriosclerosis. | International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition 19990101 |
| Mechanism of the abnormal vitamin K-dependent gamma-carboxylation process in human hepatocellular carcinomas. | Cancer 19940901 |