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Tebipenem

CAS No.:
161715-21-5
Catalog Number:
AG01EB13
Molecular Formula:
C16H21N3O4S2
Molecular Weight:
383.4856
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
98%
1 week
United States
$307
- +
10mg
98%
1 week
United States
$523
- +
50mg
98%
1 week
United States
$1307
- +
Product Description
Catalog Number:
AG01EB13
Chemical Name:
Tebipenem
CAS Number:
161715-21-5
Molecular Formula:
C16H21N3O4S2
Molecular Weight:
383.4856
MDL Number:
MFCD00936545
IUPAC Name:
(4R,5S,6S)-3-[1-(4,5-dihydro-1,3-thiazol-2-yl)azetidin-3-yl]sulfanyl-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
InChI:
InChI=1S/C16H21N3O4S2/c1-7-11-10(8(2)20)14(21)19(11)12(15(22)23)13(7)25-9-5-18(6-9)16-17-3-4-24-16/h7-11,20H,3-6H2,1-2H3,(H,22,23)/t7-,8-,10-,11-/m1/s1
InChI Key:
GXXLUDOKHXEFBQ-YJFSRANCSA-N
SMILES:
C[C@H]([C@H]1C(=O)N2[C@@H]1[C@@H](C)C(=C2C(=O)O)SC1CN(C1)C1=NCCS1)O
UNII:
Q2TWQ1I31U
Properties
Complexity:
689  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
0
Exact Mass:
383.097g/mol
Formal Charge:
0
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
383.481g/mol
Monoisotopic Mass:
383.097g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
144A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.6  
Literature
Title Journal
In vitro susceptibility of Mycobacterium tuberculosis isolates to an oral carbapenem alone or in combination with β-lactamase inhibitors. Antimicrobial agents and chemotherapy 20141101
[Clinical efficacy of tebipenem pivoxil treatment in children with pneumonia, who had no relief despite having administered oral beta-lactam antibiotics]. The Japanese journal of antibiotics 20110601
Investigation of pneumonia-causing pathogenic organisms in children and the usefulness of tebipenem pivoxil for their treatment. Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20100801
[Pharmacokinetics of tebipenem pivoxil, a novel oral carbapenem antibiotic, in experimental animals]. The Japanese journal of antibiotics 20090601
[Convulsive liability of an oral carbapenem antibiotic, tebipenem pivoxil]. The Japanese journal of antibiotics 20090601
[Antimicrobial activity of tebipenem against various clinical isolates from various specimen, mainly urinary tract]. The Japanese journal of antibiotics 20090401
[Tissue and aural discharge distribution of tebipenem pivoxil]. The Japanese journal of antibiotics 20090401
[Effect of diet on the pharmacokinetics of tebipenem pivoxil fine granules in healthy male volunteers]. The Japanese journal of antibiotics 20090401
[Clinical efficacy, safety and PK-PD analysis of tebipenem pivoxil in a phase II clinical trial in otolaryngological infections]. The Japanese journal of antibiotics 20090401
Population pharmacokinetics of tebipenem pivoxil (ME1211), a novel oral carbapenem antibiotic, in pediatric patients with otolaryngological infection or pneumonia. Drug metabolism and pharmacokinetics 20080101
Efficacy of a novel oral carbapenem, tebipenem pivoxil (TBM-PI), against experimental otitis media caused by penicillin resistant Streptococcus pneumoniae in chinchilla. Vaccine 20070322
Comparative review of the carbapenems. Drugs 20070101
[Relationship between protein binding and antimicrobial activities of antibiotics against Streptococcus pneumoniae and Haemophilus influenzae]. The Japanese journal of antibiotics 20061001
Syntheses and pharmacokinetic studies of prodrug esters for the development of oral carbapenem, L-084. The Journal of antibiotics 20060401
Properties