Amg 9810
| Title | Journal |
|---|---|
| Effects of single swim stress on changes in TRPV1-mediated plasticity in the amygdala. | Behavioural brain research 20130101 |
| Functional interactions between NMDA receptors and TRPV1 in trigeminal sensory neurons mediate mechanical hyperalgesia in the rat masseter muscle. | Pain 20120701 |
| Structure-activity relationships of vanilloid receptor agonists for arteriolar TRPV1. | British journal of pharmacology 20120301 |
| Resolving TRPV1- and TNF-α-mediated spinal cord synaptic plasticity and inflammatory pain with neuroprotectin D1. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20111019 |
| The antinociceptive potency of N-arachidonoyl-dopamine (NADA) and its interaction with endomorphin-1 at the spinal level. | Pharmacology, biochemistry, and behavior 20111001 |
| Role of TRPV1 in nociception and edema induced by monosodium urate crystals in rats. | Pain 20110801 |
| TRPM3 is a nociceptor channel involved in the detection of noxious heat. | Neuron 20110512 |
| TRPV1-antagonist AMG9810 promotes mouse skin tumorigenesis through EGFR/Akt signaling. | Carcinogenesis 20110501 |
| Synergistic role of TRPV1 and TRPA1 in pancreatic pain and inflammation. | Gastroenterology 20110401 |
| Effect of transient receptor potential vanilloid 1 (TRPV1) receptor antagonist compounds SB705498, BCTC and AMG9810 in rat models of thermal hyperalgesia measured with an increasing-temperature water bath. | European journal of pharmacology 20100901 |
| The involvement of the transient receptor potential A1 (TRPA1) in the maintenance of mechanical and cold hyperalgesia in persistent inflammation. | Pain 20100301 |
| Comparison of the peripheral mediator background of heat injury- and plantar incision-induced drop of the noxious heat threshold in the rat. | Life sciences 20100213 |
| Pharmacologic antagonism of the oral aversive taste-directed response to capsaicin in a mouse brief access taste aversion assay. | The Journal of pharmacology and experimental therapeutics 20100201 |
| Activation of TRPV1 and TRPA1 leads to muscle nociception and mechanical hyperalgesia. | Pain 20090801 |
| Differential effects of transient receptor vanilloid one (TRPV1) antagonists in acid-induced excitation of esophageal vagal afferent fibers of rats. | Neuroscience 20090630 |
| Effect of increasing temperature on TRPV1-mediated responses in isolated rat pulmonary sensory neurons. | American journal of physiology. Lung cellular and molecular physiology 20080301 |
| The role of TRPV1 in different subtypes of dorsal root ganglion neurons in rat chronic inflammatory nociception induced by complete Freund's adjuvant. | Molecular pain 20080101 |
| Three-dimensional quantitative structure-activity relationships and activity predictions of human TRPV1 channel antagonists: comparative molecular field analysis and comparative molecular similarity index analysis of cinnamides. | Journal of medicinal chemistry 20071115 |
| Novel vanilloid receptor-1 antagonists: 1. Conformationally restricted analogues of trans-cinnamides. | Journal of medicinal chemistry 20070726 |
| The potential of transient receptor potential vanilloid type 1 channel modulators for the treatment of pain. | Journal of medicinal chemistry 20070531 |
| Arvanil, anandamide and N-arachidonoyl-dopamine (NADA) inhibit emesis through cannabinoid CB1 and vanilloid TRPV1 receptors in the ferret. | The European journal of neuroscience 20070501 |
| Antihyperalgesic effects of vanilloid-1 and bradykinin-1 receptor antagonists following spinal cord injury in rats. | Journal of neurosurgery. Spine 20070501 |
| The vanilloid receptor TRPV1 is tonically activated in vivo and involved in body temperature regulation. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20070328 |
| Thermal sensitivity of isolated vagal pulmonary sensory neurons: role of transient receptor potential vanilloid receptors. | American journal of physiology. Regulatory, integrative and comparative physiology 20060901 |
| AMG 9810 [(E)-3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo[b][1,4] dioxin-6-yl)acrylamide], a novel vanilloid receptor 1 (TRPV1) antagonist with antihyperalgesic properties. | The Journal of pharmacology and experimental therapeutics 20050401 |
| Discovery of potent, orally available vanilloid receptor-1 antagonists. Structure-activity relationship of N-aryl cinnamides. | Journal of medicinal chemistry 20050113 |
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
| D-glucose-6-phosphate dehydrogenase (Entner-Doudoroff enzyme) from Pseudomonas fluorescens. Purification, properties and regulation. | European journal of biochemistry 19751115 |