1-(4-(4-(((2S,4R)-2-((1H-Imidazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)ethanone
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Testosterone metabolism of equine single CYPs of the 3A subfamily compared to the human CYP3A4. | Toxicology in vitro : an international journal published in association with BIBRA 20170601 |
Metabolic-induced cytotoxicity of diosbulbin B in CYP3A4-expressing cells. | Toxicology in vitro : an international journal published in association with BIBRA 20170201 |
Identification of vitamin D(3) target genes in human breast cancer tissue. | The Journal of steroid biochemistry and molecular biology 20161101 |
In vitro evaluation of hepatotoxic drugs in human hepatocytes from multiple donors: Identification of P450 activity as a potential risk factor for drug-induced liver injuries. | Chemico-biological interactions 20160805 |
Modulation of 17β-estradiol induced estrogenic responses in male goldfish (Carassius auratus) by benzo[a]pyrene and ketoconazole. | Environmental science and pollution research international 20160501 |
Metabolic activation of furan moiety makes Diosbulbin B hepatotoxic. | Archives of toxicology 20160401 |
Ketoconazole Stereoisomers Differentially Induce Cytochrome P450 1A1 Between Human Hepatoma HepG2 and Mouse Hepatoma Hepa1c1c7 Cells. | Journal of pharmaceutical sciences 20160301 |
Establishment of a mouse model for amiodarone-induced liver injury and analyses of its hepatotoxic mechanism. | Journal of applied toxicology : JAT 20160101 |
Changes in plasma concentrations of corticosterone and its precursors after ketoconazole administration in rats: An application of simultaneous measurement of multiple steroids using LC-MS/MS. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20160101 |
Cytotoxicity of luteolin in primary rat hepatocytes: the role of CYP3A-mediated ortho-benzoquinone metabolite formation and glutathione depletion. | Journal of applied toxicology : JAT 20151101 |
Ketoconazole induces apoptosis in rat cardiomyocytes through reactive oxygen species-mediated parkin overexpression. | Archives of toxicology 20151001 |
Testotoxicosis: Report of Two Cases, One with a Novel Mutation in LHCGR Gene. | Journal of clinical research in pediatric endocrinology 20150901 |
Ketoconazole Treatment Decreases the Viability of Immortalized Pituitary Cell Lines Associated with an Increased Expression of Apoptosis-Related Genes and Cell Cycle Inhibitors. | Journal of neuroendocrinology 20150701 |
Therapy of endocrine disease: steroidogenesis enzyme inhibitors in Cushing's syndrome. | European journal of endocrinology 20150601 |
Demethylation of neferine in human liver microsomes and formation of quinone methide metabolites mediated by CYP3A4 accentuates its cytotoxicity. | Chemico-biological interactions 20141205 |
Baboon syndrome induced by ketoconazole. | Cutaneous and ocular toxicology 20141201 |
Clinical CYP3A inhibitor alternatives to ketoconazole, clarithromycin and itraconazole, are not transported into the liver by hepatic organic anion transporting polypeptides and organic cation transporter 1. | Drug metabolism and disposition: the biological fate of chemicals 20141101 |
Effects of rifampin and ketoconazole on pharmacokinetics of morinidazole in healthy chinese subjects. | Antimicrobial agents and chemotherapy 20141001 |
Inhibition of cytochrome P450s enhances (+)-usnic acid cytotoxicity in primary cultured rat hepatocytes. | Journal of applied toxicology : JAT 20140801 |
CYP3A4 activity reduces the cytotoxic effects of okadaic acid in HepaRG cells. | Archives of toxicology 20140801 |
Studies on the antileishmanial mechanism of action of the arylimidamide DB766: azole interactions and role of CYP5122A1. | Antimicrobial agents and chemotherapy 20140801 |
Investigation of a novel series of 2-hydroxyisoquinoline-1,3(2H,4H)-diones as human immunodeficiency virus type 1 integrase inhibitors. | Journal of medicinal chemistry 20140612 |
Combination antiretroviral therapy (cART) component ritonavir significantly alters docetaxel exposure. | Cancer chemotherapy and pharmacology 20140401 |
In vivo production of novel vitamin D2 hydroxy-derivatives by human placentas, epidermal keratinocytes, Caco-2 colon cells and the adrenal gland. | Molecular and cellular endocrinology 20140305 |
Synthesis and biological evaluation of thiazoline derivatives as new antimicrobial and anticancer agents. | European journal of medicinal chemistry 20140303 |
Synthesis, antifungal activities and molecular docking studies of novel 2-(2,4-difluorophenyl)-2-hydroxy-3-(1H-1,2,4-triazol-1-yl)propyl dithiocarbamates. | European journal of medicinal chemistry 20140303 |
Molecular identification and antifungal susceptibility of yeast isolates causing fungemia collected in a population-based study in Spain in 2010 and 2011. | Antimicrobial agents and chemotherapy 20140301 |
Targeted androgen pathway suppression in localized prostate cancer: a pilot study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20140120 |
Human variation and CYP enzyme contribution in benfuracarb metabolism in human in vitro hepatic models. | Toxicology letters 20140113 |
Synthesis and biological evaluation of novel N-substituted 1H-dibenzo[a,c]carbazole derivatives of dehydroabietic acid as potential antimicrobial agents. | Bioorganic & medicinal chemistry letters 20140101 |
Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells. | PloS one 20140101 |
Enantiospecific effects of ketoconazole on aryl hydrocarbon receptor. | PloS one 20140101 |
Dual effects of ketoconazole cis-enantiomers on CYP3A4 in human hepatocytes and HepG2 Cells. | PloS one 20140101 |
Capsaicin pretreatment increased the bioavailability of cyclosporin in rats: involvement of P-glycoprotein and CYP 3A inhibition. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20131201 |
Hytramycins V and I, anti-Mycobacterium tuberculosis hexapeptides from a Streptomyces hygroscopicus strain. | Journal of natural products 20131122 |
3-Aryl-4-acyloxyethoxyfuran-2(5H)-ones as inhibitors of tyrosyl-tRNA synthetase: synthesis, molecular docking and antibacterial evaluation. | Bioorganic & medicinal chemistry 20130901 |
Synthesis, in vitro antifungal activity and in silico study of 3-(1,2,4-triazol-1-yl)flavanones. | European journal of medicinal chemistry 20130801 |
Interaction of 17β-estradiol and ketoconazole on endocrine function in goldfish (Carassius auratus). | Aquatic toxicology (Amsterdam, Netherlands) 20130515 |
Novel yeast-based strategy unveils antagonist binding regions on the nuclear xenobiotic receptor PXR. | The Journal of biological chemistry 20130510 |
Effect of ketoconazole on the pharmacokinetics of the 11β-hydroxysteroid dehydrogenase type 1 inhibitor ABT-384 and its two active metabolites in healthy volunteers: population analysis of data from a drug-drug interaction study. | Drug metabolism and disposition: the biological fate of chemicals 20130501 |
Synthesis and evaluation of non-dimeric HCV NS5A inhibitors. | Bioorganic & medicinal chemistry letters 20130401 |
Coordinated roles of pregnane X receptor and constitutive androstane receptor in autoinduction of voriconazole metabolism in mice. | Antimicrobial agents and chemotherapy 20130301 |
Transport inhibition of digoxin using several common P-gp expressing cell lines is not necessarily reporting only on inhibitor binding to P-gp. | PloS one 20130101 |
Fluconazole inhibits human adrenocortical steroidogenesis in vitro. | The Journal of endocrinology 20121201 |
Inhibition of CYP3A4 by 6',7'-dihydroxybergamottin in human CYP3A4 over-expressed hepG2 cells. | The Journal of pharmacy and pharmacology 20121201 |
Binding processes determine the stereoselective intestinal and hepatic extraction of verapamil in vivo. | Molecular pharmaceutics 20121105 |
A reappraisal of the medical therapy with steroidogenesis inhibitors in Cushing's syndrome. | Clinical endocrinology 20121101 |
Catecholaminergic signalling through thymic nerve fibres, thymocytes and stromal cells is dependent on both circulating and locally synthesized glucocorticoids. | Experimental physiology 20121101 |
Impact of nonlinear midazolam pharmacokinetics on the magnitude of the midazolam-ketoconazole interaction in rats. | Xenobiotica; the fate of foreign compounds in biological systems 20121101 |
Assessment of the drug interaction risk for remogliflozin etabonate, a sodium-dependent glucose cotransporter-2 inhibitor: evidence from in vitro, human mass balance, and ketoconazole interaction studies. | Drug metabolism and disposition: the biological fate of chemicals 20121101 |
Synthesis and antifungal activity of diverse C-2 pyridinyl and pyridinylvinyl substituted quinolines. | Bioorganic & medicinal chemistry 20121101 |
Synthesis, characterization and biological evaluation of some novel 2,4-thiazolidinediones as potential cytotoxic, antimicrobial and antihyperglycemic agents. | Bioorganic & medicinal chemistry letters 20121015 |
Structure-activity relationship study of nitrosopyrimidines acting as antifungal agents. | Bioorganic & medicinal chemistry 20121015 |
Evaluation of the effects of rifampicin, ketoconazole and erythromycin on the steady-state pharmacokinetics of the components of a novel oral contraceptive containing estradiol valerate and dienogest in healthy postmenopausal women. | Contraception 20121001 |
Human aldosterone synthase: recombinant expression in E. coli and purification enables a detailed biochemical analysis of the protein on the molecular level. | The Journal of steroid biochemistry and molecular biology 20121001 |
Course of pregnancies in women with Cushing's disease treated by gamma-knife. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20121001 |
The effects on metabolic clearance when administering a potent CYP3A autoinducer with the prototypic CYP3A inhibitor, ketoconazole. | Drug metabolism and disposition: the biological fate of chemicals 20121001 |
Prototheca wickerhamii as a cause of neuroinfection in a child with congenital hydrocephalus. First case of human protothecosis in Poland. | Diagnostic microbiology and infectious disease 20121001 |
Mouse precision-cut liver slices as an ex vivo model to study idiosyncratic drug-induced liver injury. | Chemical research in toxicology 20120917 |
Identification of priority pharmaceuticals in the water environment of China. | Chemosphere 20120901 |
Discovery of a highly selective CYP3A4 inhibitor suitable for reaction phenotyping studies and differentiation of CYP3A4 and CYP3A5. | Drug metabolism and disposition: the biological fate of chemicals 20120901 |
Studies on the mechanisms of superagonistic pro-differentiating activities of side-chain modified analogs of vitamin D2. | Oncology reports 20120901 |
Involvement of the neurosteroid 7α-hydroxypregnenolone in the courtship behavior of the male newt Cynops pyrrhogaster. | Hormones and behavior 20120901 |
Laurene-type sesquiterpenes from the Red Sea red alga Laurencia obtusa as potential antitumor-antimicrobial agents. | European journal of medicinal chemistry 20120901 |
Effect of ketoconazole on the pharmacokinetic profile of buprenorphine following administration of a once-weekly buprenorphine transdermal system. | Clinical drug investigation 20120901 |
Phase I studies of sirolimus alone or in combination with pharmacokinetic modulators in advanced cancer patients. | Clinical cancer research : an official journal of the American Association for Cancer Research 20120901 |
Ascending single-dose study of the safety profile, tolerability, and pharmacokinetics of bosutinib coadministered with ketoconazole to healthy adult subjects. | Clinical therapeutics 20120901 |
The prognostic factors of effective ketoconazole treatment for metastatic castration-resistant prostate cancer: who can benefit from ketoconazole therapy? | Asian journal of andrology 20120901 |
Isolated Cushing's syndrome in early infancy due to left adrenal adenoma: an unusual aetiology. | Journal of clinical research in pediatric endocrinology 20120901 |
Differentiating mucosal and hepatic metabolism of budesonide by local pretreatment with increasing doses of ketoconazole in the proximal jejunum. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120815 |
Evaluation of saliva flow rates, Candida colonization and susceptibility of Candida strains after head and neck radiation. | Clinical oral investigations 20120801 |
A randomized, crossover, placebo- and moxifloxacin-controlled study to evaluate the effects of bosutinib (SKI-606), a dual Src/Abl tyrosine kinase inhibitor, on cardiac repolarization in healthy adult subjects. | International journal of cancer 20120801 |
In vitro activities of antifungal agents against clinical isolates of dermatophytes from animals. | The Journal of veterinary medical science 20120801 |
Drug-drug interactions and cooperative effects detected in electrochemically driven human cytochrome P450 3A4. | Bioelectrochemistry (Amsterdam, Netherlands) 20120801 |
Synthesis, antimicrobial and cytotoxic activities of sulfone linked bis heterocycles. | European journal of medicinal chemistry 20120801 |
Synthesis and evaluation of novel potent HCV NS5A inhibitors. | Bioorganic & medicinal chemistry letters 20120715 |
Influence of Pluronic 85 and ketoconazole on disposition and efficacy of ivermectin in sheep infected with a multiple resistant Haemonchus contortus isolate. | Veterinary parasitology 20120706 |
Synthesis of benzimidazolyl-1,3,4-oxadiazol-2ylthio-N-phenyl (benzothiazolyl) acetamides as antibacterial, antifungal and antituberculosis agents. | European journal of medicinal chemistry 20120701 |
The fatty acid 8,11-diol synthase of Aspergillus fumigatus is inhibited by imidazole derivatives and unrelated to PpoB. | Lipids 20120701 |
Bioactive briarane diterpenoids from the South China Sea gorgonian Dichotella gemmacea. | Bioorganic & medicinal chemistry letters 20120701 |
CDR4 is the major contributor to azole resistance among four Pdr5p-like ABC transporters in Neurospora crassa. | Fungal biology 20120701 |
Identification, synthesis, and biological evaluation of the metabolites of 3-amino-6-(3'-aminopropyl)-5H-indeno[1,2-c]isoquinoline-5,11-(6H)dione (AM6-36), a promising rexinoid lead compound for the development of cancer chemotherapeutic and chemopreventive agents. | Journal of medicinal chemistry 20120628 |
Cytochrome P450 3A4 inhibition by ketoconazole: tackling the problem of ligand cooperativity using molecular dynamics simulations and free-energy calculations. | Journal of chemical information and modeling 20120625 |
A time-course analysis of effects of the steroidogenesis inhibitor ketoconazole on components of the hypothalamic-pituitary-gonadal axis of fathead minnows. | Aquatic toxicology (Amsterdam, Netherlands) 20120615 |
CYP3A-mediated apoptosis of dauricine in cultured human bronchial epithelial cells and in lungs of CD-1 mice. | Toxicology and applied pharmacology 20120615 |
The effect of CYP3A4 inhibition or induction on the pharmacokinetics and pharmacodynamics of orally administered ruxolitinib (INCB018424 phosphate) in healthy volunteers. | Journal of clinical pharmacology 20120601 |
Lack of significant effect of bilastine administered at therapeutic and supratherapeutic doses and concomitantly with ketoconazole on ventricular repolarization: results of a thorough QT study (TQTS) with QT-concentration analysis. | Journal of clinical pharmacology 20120601 |
Tolbutamide hydroxylation by hepatic microsomes from Atlantic salmon (Salmo salar L.). | Molecular biology reports 20120601 |
Design and synthesis of new 4-pyrazolin-3-yl-1,2,3-triazoles and 1,2,3-triazol-4-yl-pyrazolin-1-ylthiazoles as potential antimicrobial agents. | European journal of medicinal chemistry 20120601 |
Distribution, behavior and fate of azole antifungals during mechanical, biological, and chemical treatments in sewage treatment plants in China. | The Science of the total environment 20120601 |
Apparent triclabendazole-resistant human Fasciola hepatica infection, the Netherlands. | Emerging infectious diseases 20120601 |
Influence of P-glycoprotein modulation on plasma concentrations and pharmacokinetics of orally administered prednisolone in dogs. | American journal of veterinary research 20120601 |
Fluconazole exposure rather than clonal spreading is correlated with the emergence of Candida glabrata with cross-resistance to triazole antifungal agents. | The Kaohsiung journal of medical sciences 20120601 |
Implication of free cholesterol in LC-MS response enhancement. | Bioanalysis 20120601 |
Therapeutic effectiveness of Ageratina pichinchensis on the treatment of chronic interdigital tinea pedis: a randomized, double-blind clinical trial. | Journal of alternative and complementary medicine (New York, N.Y.) 20120601 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. | Journal of medicinal chemistry 20120524 |
Effects of ketoconazole and valproic acid on the pharmacokinetics of the next generation NNRTI, lersivirine (UK-453,061), in healthy adult subjects. | British journal of clinical pharmacology 20120501 |
Drug-drug interactions between ketoconazole and berberine in rats: pharmacokinetic effects benefit pharmacodynamic synergism. | Phytotherapy research : PTR 20120501 |
The effect of multiple doses of rifampin and ketoconazole on the single-dose pharmacokinetics of ridaforolimus. | Cancer chemotherapy and pharmacology 20120501 |
Human testis steroidogenesis is inhibited by phthalates. | Human reproduction (Oxford, England) 20120501 |
Synthesis of novel spirooxindole derivatives by one pot multicomponent reaction and their antimicrobial activity. | European journal of medicinal chemistry 20120501 |
Preclinical metabolism of LB42908, a novel farnesyl transferase inhibitor, and its effects on the cytochrome P450 isozyme activities. | Bioorganic & medicinal chemistry letters 20120501 |
The stepwise selection for ketoconazole resistance induces upregulation of C14-demethylase (CYP51) in Leishmania amazonensis. | Memorias do Instituto Oswaldo Cruz 20120501 |
Stereoselective metabolism of tetrahydropalmatine enantiomers in rat liver microsomes. | Chirality 20120501 |
Effects of ketoconazole and rifampicin on the pharmacokinetics of gemigliptin, a dipeptidyl peptidase-IV inhibitor: a crossover drug-drug interaction study in healthy male Korean volunteers. | Clinical therapeutics 20120501 |
Hydrogel of ketoconazole and PAMAM dendrimers: formulation and antifungal activity. | Molecules (Basel, Switzerland) 20120418 |
New triazole derivatives as antifungal agents: synthesis via click reaction, in vitro evaluation and molecular docking studies. | Bioorganic & medicinal chemistry letters 20120415 |
Development of a new class of aromatase inhibitors: design, synthesis and inhibitory activity of 3-phenylchroman-4-one (isoflavanone) derivatives. | Bioorganic & medicinal chemistry 20120415 |
Molecular cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Malassezia globosa, a potential antidandruff target. | Journal of medicinal chemistry 20120412 |
Effect of cytochrome P450 3A4 inhibitor ketoconazole on risperidone pharmacokinetics in healthy volunteers. | Journal of clinical pharmacy and therapeutics 20120401 |
Involvement of P-glycoprotein and cytochrome P450 3A in the metabolism of florfenicol of rabbits. | Journal of veterinary pharmacology and therapeutics 20120401 |
Effects of CYP3A4 inhibition and induction on the pharmacokinetics and pharmacodynamics of tolvaptan, a non-peptide AVP antagonist in healthy subjects. | British journal of clinical pharmacology 20120401 |
Iatrogenic heart block during treatment of a patient with Cushing's syndrome: report of a case. | Endocrine 20120401 |
Orteronel (TAK-700), a novel non-steroidal 17,20-lyase inhibitor: effects on steroid synthesis in human and monkey adrenal cells and serum steroid levels in cynomolgus monkeys. | The Journal of steroid biochemistry and molecular biology 20120401 |
The hypercoagulable state in Cushing's disease is associated with increased levels of procoagulant factors and impaired fibrinolysis, but is not reversible after short-term biochemical remission induced by medical therapy. | The Journal of clinical endocrinology and metabolism 20120401 |
Predicting drug candidate victims of drug-drug interactions, using microdosing. | Clinical pharmacokinetics 20120401 |
Increasing evidence for and regulation of a human placental endogenous digitalis-like factor. | Reproductive sciences (Thousand Oaks, Calif.) 20120401 |
Regioselective synthesis and antimicrobial activities of some novel aryloxyacetic acid derivatives. | European journal of medicinal chemistry 20120401 |
Comparison of three fluorescent CYP3A substrates in two vertebrate models: pig and Atlantic salmon. | Animal : an international journal of animal bioscience 20120401 |
In vitro antifungal susceptibility of Malassezia pachydermatis from dogs with and without skin lesions. | Veterinary microbiology 20120323 |
Contemporary experience with ketoconazole in patients with metastatic castration-resistant prostate cancer: clinical factors associated with PSA response and disease progression. | The Prostate 20120301 |
Pharmacokinetic interaction between domperidone and ketoconazole leads to QT prolongation in healthy volunteers: a randomized, placebo-controlled, double-blind, crossover study. | British journal of clinical pharmacology 20120301 |
H295R cells as a model for steroidogenic disruption: a broader perspective using simultaneous chemical analysis of 7 key steroid hormones. | Toxicology in vitro : an international journal published in association with BIBRA 20120301 |
Hypercalcemia, hypercalciuria, and elevated calcitriol concentrations with autosomal dominant transmission due to CYP24A1 mutations: effects of ketoconazole therapy. | The Journal of clinical endocrinology and metabolism 20120301 |
Take another CYP: confirming a novel mechanism for 'idiopathic' hypercalcemia. | The Journal of clinical endocrinology and metabolism 20120301 |
An Aruban man with fever, abdominal mass and eosinophilia. | The Netherlands journal of medicine 20120301 |
Potentiation of triclabendazole action in vivo against a triclabendazole-resistant isolate of Fasciola hepatica following its co-administration with the metabolic inhibitor, ketoconazole. | Veterinary parasitology 20120227 |
Tocol modified glycol chitosan for the oral delivery of poorly soluble drugs. | International journal of pharmaceutics 20120227 |
[Efficacy of low dose ketoconazole therapy for Chinese patients with castration resistant prostate cancer]. | Zhonghua yi xue za zhi 20120227 |
Synthesis of novel brassinosteroid biosynthesis inhibitors based on the ketoconazole scaffold. | Bioorganic & medicinal chemistry letters 20120215 |
Synthesis of novel sulfonamide-1,2,4-triazoles, 1,3,4-thiadiazoles and 1,3,4-oxadiazoles, as potential antibacterial and antifungal agents. Biological evaluation and conformational analysis studies. | Bioorganic & medicinal chemistry 20120215 |
Effect of ketoconazole on the pharmacokinetics of axitinib in healthy volunteers. | Investigational new drugs 20120201 |
Malformation spectrum induced by ketoconazole after single administration to pregnant rats during the critical period - comparison with vitamin A-induced malformation spectrum. | Journal of applied toxicology : JAT 20120201 |
Enhancement of β-carotene production by over-expression of HMG-CoA reductase coupled with addition of ergosterol biosynthesis inhibitors in recombinant Saccharomyces cerevisiae. | Current microbiology 20120201 |
Synthesis and biological evaluation of some thiazolidinones as antimicrobial agents. | European journal of medicinal chemistry 20120201 |
Ketoconazole-associated preferential increase in dopamine D2 receptor occupancy in striatum compared to pituitary in vivo: role for drug transporters? | Journal of clinical psychopharmacology 20120201 |
Effects of efonidipine on the pharmacokinetics and pharmacodynamics of repaglinide: possible role of CYP3A4 and P-glycoprotein inhibition by efonidipine. | Journal of pharmacokinetics and pharmacodynamics 20120201 |
[Blastomycosis in Morocco: imported mycosis]. | Revue de pneumologie clinique 20120201 |
Advances in medical therapies for Cushing's syndrome. | Discovery medicine 20120201 |
[Transport of limonin in rat intestine in situ and Caco-2 cells in vitro]. | Yao xue xue bao = Acta pharmaceutica Sinica 20120201 |
Tinea versicolor: understanding effective treatment options. | The Nurse practitioner 20120119 |
Synthesis, characterization and in vitro biological evaluation of some novel diarylsulfonylureas as potential cytotoxic and antimicrobial agents. | Bioorganic & medicinal chemistry letters 20120115 |
Radiation port dermatophytosis: tinea corporis occurring at the site of irradiated skin. | Dermatology online journal 20120115 |
Determination of metabolic profile of anti-malarial trioxane CDRI 99/411 in rat liver microsomes using HPLC. | Biomedical chromatography : BMC 20120101 |
Identification of ketoconazole as an AhR-Nrf2 activator in cultured human keratinocytes: the basis of its anti-inflammatory effect. | The Journal of investigative dermatology 20120101 |
Application of PBPK modelling in drug discovery and development at Pfizer. | Xenobiotica; the fate of foreign compounds in biological systems 20120101 |
Ultrasound-enhanced surfactant-assisted dispersive liquid-liquid microextraction and high-performance liquid chromatography for determination of ketoconazole and econazole nitrate in human blood. | Analytical and bioanalytical chemistry 20120101 |
Discovery of a novel class of aldol-derived 1,2,3-triazoles: potent and selective inhibitors of human cytochrome P450 19A1 (aromatase). | Bioorganic & medicinal chemistry letters 20120101 |
Antifungal activities of novel non-azole molecules against S. cerevisiae and C. albicans. | European journal of medicinal chemistry 20120101 |
Synthesis, antimicrobial, antimycobacterial and structure-activity relationship of substituted pyrazolo-, isoxazolo-, pyrimido- and mercaptopyrimidocyclohepta[b]indoles. | European journal of medicinal chemistry 20120101 |
Isoxazoles incorporated N-substituted decahydroquinolines: a precursor to the next generation antimicrobial drug. | European journal of medicinal chemistry 20120101 |
The AhR-Nrf2 pathway in keratinocytes: on the road to chemoprevention? | The Journal of investigative dermatology 20120101 |
Lack of drug interaction between the migraine drug MAP0004 (orally inhaled dihydroergotamine) and a CYP3A4 inhibitor in humans. | Cephalalgia : an international journal of headache 20120101 |
Comparison of the effect of non-antifungal and antifungal agents on Candida isolates from the gastrointestinal tract. | Archives of Iranian medicine 20120101 |
Efficacy and safety of venous thromboembolism prophylaxis with apixaban in major orthopedic surgery. | Therapeutics and clinical risk management 20120101 |
Roles of adapalene in the treatment of pityriasis versicolor. | Dermatology (Basel, Switzerland) 20120101 |
The effect of ketoconazole on post-burn inflammation, hypermetabolism and clinical outcomes. | PloS one 20120101 |
Disappearance of pituitary macro adenoma with combination of ketoconazole and cabergoline treatment: an unusual case of Cushing's syndrome with interesting findings. | BMJ case reports 20120101 |
Stimulation of human monocytic THP-1 cells by metabolic activation of hepatotoxic drugs. | Drug metabolism and pharmacokinetics 20120101 |
Retigeric acid B enhances the efficacy of azoles combating the virulence and biofilm formation of Candida albicans. | Biological & pharmaceutical bulletin 20120101 |
Comparison between two culture media for in vitro evaluation of antifungal susceptibility of the Sporothrix schenckii complex. | Anais brasileiros de dermatologia 20120101 |
Telaprevir: pharmacokinetics and drug interactions. | Antiviral therapy 20120101 |
Blockade of K+ and Ca2+ channels by azole antifungal agents in neonatal rat ventricular myocytes. | Biological & pharmaceutical bulletin 20120101 |
The cytochrome P450 inhibitor, ketoconazole, inhibits oxidized linoleic acid metabolite-mediated peripheral inflammatory pain. | Molecular pain 20120101 |
Synthesis and antileishmanial evaluation of 1-aryl-4-(4,5-dihydro-1H-imidazol-2-yl)-1H-pyrazole derivatives. | Bioorganic & medicinal chemistry letters 20111215 |
A new antifungal briarane diterpenoid from the gorgonian Junceella juncea Pallas. | Bioorganic & medicinal chemistry letters 20111215 |
Novel (E)-1-(4-methyl-2-(alkylamino)thiazol-5-yl)-3-arylprop-2-en-1-ones as potent antimicrobial agents. | Bioorganic & medicinal chemistry 20111215 |
Effect of ketoconazole on the pharmacokinetics of oral bosutinib in healthy subjects. | Journal of clinical pharmacology 20111201 |
Precipitation in and supersaturation of contents of the upper small intestine after administration of two weak bases to fasted adults. | Pharmaceutical research 20111201 |
Cytotoxicity of 3-(3,5-dichlorophenyl)-2,4-thiazolidinedione (DCPT) and analogues in wild type and CYP3A4 stably transfected HepG2 cells. | Toxicology in vitro : an international journal published in association with BIBRA 20111201 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
Effect of different durations and formulations of diltiazem on the single-dose pharmacokinetics of midazolam: how long do we go? | Journal of clinical pharmacology 20111101 |
Effect of hyperlipidemia on ketoconazole-midazolam drug-drug interaction in rat. | Journal of pharmaceutical sciences 20111101 |
A random comparative study of terbinafine versus griseofulvin in patients with tinea capitis in Western China. | Mycopathologia 20111101 |
Antifungal susceptibility and virulence attributes of bloodstream isolates of Candida from Hong Kong and Finland. | Mycopathologia 20111101 |
Synthesis and antimicrobial activity of amido linked pyrrolyl and pyrazolyl-oxazoles, thiazoles and imidazoles. | European journal of medicinal chemistry 20111101 |
Synthesis and biological evaluation of some novel triazol-3-ones as antimicrobial agents. | Bioorganic & medicinal chemistry letters 20111101 |
Synthesis and anticandidal activity of new triazolothiadiazine derivatives. | European journal of medicinal chemistry 20111101 |
The influence of modulation of P-glycoprotein and /or cytochrome P450 3A on the pharmacokinetics and pharmacodynamics of orally administered morphine in dogs. | Journal of veterinary pharmacology and therapeutics 20111001 |
Exploring the possible metabolism mediated interaction of Glycyrrhiza glabra extract with CYP3A4 and CYP2D6. | Phytotherapy research : PTR 20111001 |
Inhibition of triclabendazole metabolism in vitro by ketoconazole increases disruption to the tegument of a triclabendazole-resistant isolate of Fasciola hepatica. | Parasitology research 20111001 |
Overt immune dysfunction after Cushing's syndrome remission: a consecutive case series and review of the literature. | The Journal of clinical endocrinology and metabolism 20111001 |
Tyrosyl-tRNA synthetase inhibitors as antibacterial agents: synthesis, molecular docking and structure-activity relationship analysis of 3-aryl-4-arylaminofuran-2(5H)-ones. | European journal of medicinal chemistry 20111001 |
Enantioselective capillary electrophoresis for the assessment of CYP3A4-mediated ketamine demethylation and inhibition in vitro. | Electrophoresis 20111001 |
Effects of CYP inhibitors on precocene I metabolism and toxicity in rat liver slices. | Chemico-biological interactions 20110905 |
Therapeutic efficacy of topical OLEOZON® in patients suffering from onychomycosis. | Mycoses 20110901 |
Successful outcome of pregnancy in a patient with Cushing's disease under treatment with ketoconazole during the first trimester of gestation. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 20110901 |
Investigating the effect of moisture protection on solid-state stability and dissolution of fenofibrate and ketoconazole solid dispersions using PXRD, HSDSC and Raman microscopy. | Drug development and industrial pharmacy 20110901 |
Arachidonic acid products in airway nociceptor activation during acute lung injury. | Experimental physiology 20110901 |
Molecular complexes of ketaconazole and oxatomide with p-chloranil: spectroscopic and spectrofluorimetric studies. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20110901 |
Design, synthesis and antimicrobial activity of chiral 2-(substituted-hydroxyl)-3-(benzo[d]oxazol-5-yl)propanoic acid derivatives. | European journal of medicinal chemistry 20110901 |
A novel biotransformation of alkyl aminopyrrolidine to aminopiperidine ring by human CYP3A. | Drug metabolism and disposition: the biological fate of chemicals 20110901 |
Effect of ketoconazole-mediated CYP3A4 inhibition on clinical pharmacokinetics of panobinostat (LBH589), an orally active histone deacetylase inhibitor. | Cancer chemotherapy and pharmacology 20110901 |
Mitotane, metyrapone, and ketoconazole combination therapy as an alternative to rescue adrenalectomy for severe ACTH-dependent Cushing's syndrome. | The Journal of clinical endocrinology and metabolism 20110901 |
A phase II clinical trial of neoadjuvant ketoconazole and docetaxel chemotherapy before radical prostatectomy in high risk patients. | The Journal of urology 20110901 |
Editorial comment. | The Journal of urology 20110901 |
Synthesis and studies of novel 2-(4-cyano-3-trifluoromethylphenyl amino)-4-(quinoline-4-yloxy)-6-(piperazinyl/piperidinyl)-s-triazines as potential antimicrobial, antimycobacterial and anticancer agents. | European journal of medicinal chemistry 20110901 |
Pulmonary histoplasmosis presenting with the reversed halo sign on high-resolution CT scan. | Chest 20110901 |
In vitro susceptibility of fluconazole-susceptible and -resistant isolates of Malassezia pachydermatis against azoles. | Veterinary microbiology 20110826 |
Cytotoxic bipyridines from the marine-derived actinomycete Actinoalloteichus cyanogriseus WH1-2216-6. | Journal of natural products 20110826 |
Hydroxylation of DHEA, androstenediol and epiandrosterone by Mortierella isabellina AM212. Evidence indicating that both constitutive and inducible hydroxylases catalyze 7α- as well as 7β-hydroxylations of 5-ene substrates. | Organic & biomolecular chemistry 20110807 |
The effect of vitamin D3 and ketoconazole combination on VDR-mediated P-gp expression and function in human colon adenocarcinoma cells: implications in drug disposition and resistance. | Basic & clinical pharmacology & toxicology 20110801 |
Effects of strong CYP2D6 and 3A4 inhibitors, paroxetine and ketoconazole, on the pharmacokinetics and cardiovascular safety of tamsulosin. | British journal of clinical pharmacology 20110801 |
Substrate specificity and ligand interactions of CYP26A1, the human liver retinoic acid hydroxylase. | Molecular pharmacology 20110801 |
Hepatic cytochrome P450s attenuate the cytotoxicity induced by leflunomide and its active metabolite A77 1726 in primary cultured rat hepatocytes. | Toxicological sciences : an official journal of the Society of Toxicology 20110801 |
Synthesis and antimicrobial evaluation of new benzofuran derivatives. | European journal of medicinal chemistry 20110801 |
The pharmacological inhibition of sterol biosynthesis in Leishmania is counteracted by enhancement of LDL endocytosis. | Acta tropica 20110801 |
Improved treatment of visceral leishmaniasis (kala-azar) by using combination of ketoconazole, miltefosine with an immunomodulator-Picroliv. | Acta tropica 20110801 |
Higher throughput human hepatocyte assays for the evaluation of time-dependent inhibition of CYP3A4. | Drug metabolism letters 20110801 |
Auto-inhibition of verapamil metabolism in rat hepatocytes of gel entrapment culture. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20110801 |
Bioactive 11,20-epoxy-3,5(16)-diene briarane diterpenoids from the South China Sea gorgonian Dichotella gemmacea. | Journal of natural products 20110722 |
Spanlastics--a novel nanovesicular carrier system for ocular delivery. | International journal of pharmaceutics 20110715 |
Bioavailability considerations in evaluating drug-drug interactions using the population pharmacokinetic approach. | Journal of clinical pharmacology 20110701 |
Low dose of ketoconazole in patients with prostate adenocarcinoma resistant to pharmacological castration. | BJU international 20110701 |
Nanoparticle formation and growth during in vitro dissolution of ketoconazole solid dispersion. | Journal of pharmaceutical sciences 20110701 |
Fenretinide metabolism in humans and mice: utilizing pharmacological modulation of its metabolic pathway to increase systemic exposure. | British journal of pharmacology 20110701 |
Secondary hormonal manipulations in the treatment of castration refractory prostate cancer. | BJU international 20110701 |
Design, synthesis and antifungal activities of novel 1,2,4-triazole derivatives. | European journal of medicinal chemistry 20110701 |
Antifungal quinazolinones from marine-derived Bacillus cereus and their preparation. | Bioorganic & medicinal chemistry letters 20110701 |
Practical synthesis, anticonvulsant, and antimicrobial activity of N-allyl and N-propargyl di(indolyl)indolin-2-ones. | Bioorganic & medicinal chemistry letters 20110701 |
4-alkoxy-3-arylfuran-2(5H)-ones as inhibitors of tyrosyl-tRNA synthetase: synthesis, molecular docking and antibacterial evaluation. | Bioorganic & medicinal chemistry 20110701 |
Efficacious and safe management of moderate to severe scalp seborrhoeic dermatitis using clobetasol propionate shampoo 0·05% combined with ketoconazole shampoo 2%: a randomized, controlled study. | The British journal of dermatology 20110701 |
Synergistic effects of tetrandrine on the antifungal activity of topical ketoconazole cream in the treatment of dermatophytoses: a clinical trial. | Chinese journal of integrative medicine 20110701 |
Drug metabolism of CYP3A4, CYP2C9 and CYP2D6 substrates in pigs and humans. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20110614 |
Investigating effect of microemulsion components: In vitro permeation of ketoconazole. | Pharmaceutical development and technology 20110601 |
Prevalence and antifungal resistance profile of Candida spp. oral isolates from patients with type 1 and 2 diabetes mellitus. | Archives of oral biology 20110601 |
Cushing's syndrome due to a pancreatic neuroendocrine tumor metastatic to the ovaries: a clinicopathological description of a case. | Endocrine pathology 20110601 |
Melatonin and steroid hormones activate intermembrane Cu,Zn-superoxide dismutase by means of mitochondrial cytochrome P450. | Free radical biology & medicine 20110601 |
Tinea capitis versus acne keloidalis nuchae with Trichophyton violaceum superinfection. | Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia 20110601 |
[Bilateral conjunctival oedema as a symptom of adrenal adenocarcinoma]. | Archivos de la Sociedad Espanola de Oftalmologia 20110601 |
Pseudotumor cerebri during Cushing's disease treatment with ketoconazole. | Arquivos brasileiros de endocrinologia e metabologia 20110601 |
Thiazole-based chalcones as potent antimicrobial agents. Synthesis and biological evaluation. | Bioorganic & medicinal chemistry 20110515 |
Enhancement of triclabendazole action in vivo against a triclabendazole-resistant isolate of Fasciola hepatica by co-treatment with ketoconazole. | Veterinary parasitology 20110511 |
In vivo investigation in pigs of intestinal absorption, hepatobiliary disposition, and metabolism of the 5α-reductase inhibitor finasteride and the effects of coadministered ketoconazole. | Drug metabolism and disposition: the biological fate of chemicals 20110501 |
Synthesis, antimicrobial, antioxidant, anti-hemolytic and cytotoxic evaluation of new imidazole-based heterocycles. | European journal of medicinal chemistry 20110501 |
Assessment of milling-induced disorder of two pharmaceutical compounds. | Journal of pharmaceutical sciences 20110501 |
Management of pituitary tumors in pregnancy. | Nature reviews. Endocrinology 20110501 |
Antifungal, cytotoxic and SAR studies of a series of N-alkyl, N-aryl and N-alkylphenyl-1,4-pyrrolediones and related compounds. | Bioorganic & medicinal chemistry 20110501 |
The effects of concurrent administration of cytochrome P-450 inhibitors on the pharmacokinetics of oral methadone in healthy dogs. | Veterinary anaesthesia and analgesia 20110501 |
[Management of invasive fungal infections in children]. | Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20110501 |
An azole-resistant isolate of Malassezia pachydermatis. | Veterinary microbiology 20110421 |
Fine-tuning the selectivity of aldosterone synthase inhibitors: structure-activity and structure-selectivity insights from studies of heteroaryl substituted 1,2,5,6-tetrahydropyrrolo[3,2,1-ij]quinolin-4-one derivatives. | Journal of medicinal chemistry 20110414 |
Synthesis and biological activity of 2-(bis((1,3,4-oxadiazolyl/1,3,4-thiadiazolyl)methylthio)methylene)malononitriles. | European journal of medicinal chemistry 20110401 |
Concurrent assessment of hepatic and intestinal cytochrome P450 3A activities using deuterated alfentanil. | Clinical pharmacology and therapeutics 20110401 |
Pharmacokinetics of oral neratinib during co-administration of ketoconazole in healthy subjects. | British journal of clinical pharmacology 20110401 |
Pharmacokinetic interactions between alitretinoin and ketoconazole or simvastatin or ciclosporin A. | Clinical and experimental dermatology 20110401 |
Inhibitory effects of ketoconazole and rifampin on OAT1 and OATP1B1 transport activities: considerations on drug-drug interactions. | Biopharmaceutics & drug disposition 20110401 |
Nonhealing scalp wound infected with Aspergillus niger in an elderly patient. | Cutis 20110401 |
Low dose of ketoconazole in patients with prostate adenocarcinoma resistant to pharmacological castration. | BJU international 20110401 |
Design, synthesis, and biological evaluation of imidazolyl derivatives of 4,7-disubstituted coumarins as aromatase inhibitors selective over 17-α-hydroxylase/C17-20 lyase. | Journal of medicinal chemistry 20110324 |
Marginal increase of sunitinib exposure by grapefruit juice. | Cancer chemotherapy and pharmacology 20110301 |
Crucial role of cytochrome P450 in hepatotoxicity induced by 2,3-dimethoxy-1,4-naphthoquinone in rats. | Journal of applied toxicology : JAT 20110301 |
Evaluation of the origin of a sample of Sporothrix schenckii that caused contamination of a researcher in Southern Brazil. | Mycopathologia 20110301 |
CYP3A-mediated generation of aldehyde and hydrazine in atazanavir metabolism. | Drug metabolism and disposition: the biological fate of chemicals 20110301 |
Synthesis, structure, molecular docking, and structure-activity relationship analysis of enamines: 3-aryl-4-alkylaminofuran-2(5H)-ones as potential antibacterials. | Bioorganic & medicinal chemistry 20110301 |
[Castration resistant prostate cancer 2011]. | Aktuelle Urologie 20110301 |
First description of onychomycosis caused by Chrysosporium keratinophilum in captive Bennett's wallabies (Macropus rufogriseus rufogriseus). | Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20110301 |
Unexpected effect of rifampin on the pharmacokinetics of linezolid: in silico and in vitro approaches to explain its mechanism. | Journal of clinical pharmacology 20110201 |
Effects of ketoconazole on the in vivo biotransformation and hepatobiliary transport of the thrombin inhibitor AZD0837 in pigs. | Drug metabolism and disposition: the biological fate of chemicals 20110201 |
The effect of increased lipoprotein levels on the pharmacokinetics of ketoconazole enantiomers in the rat. | Xenobiotica; the fate of foreign compounds in biological systems 20110201 |
Application of validated RP-HPLC method for simultaneous determination of docetaxel and ketoconazole in solid lipid nanoparticles. | Journal of chromatographic science 20110201 |
Mechanism of cytochrome P450-3A inhibition by ketoconazole. | The Journal of pharmacy and pharmacology 20110201 |
[Evaluation of efficacy of ketoconazole 800 mg-clindamycin 100 mg tablets vaginal against ketoconazole 800 mg- clindamycin 100 mg vaginal capsules in candida vaginitis and vaginosis]. | Ginecologia y obstetricia de Mexico 20110201 |
Cytochrome P450 3A4 inhibitory constituents of the wood of Taxus yunnanensis. | Journal of natural products 20110128 |
Radical scavenging and antioxidant activities of isocoumarins and a phthalide from the endophytic fungus Colletotrichum sp. | Journal of natural products 20110128 |
New drug-like hydroxyphenylnaphthol steroidomimetics as potent and selective 17β-hydroxysteroid dehydrogenase type 1 inhibitors for the treatment of estrogen-dependent diseases. | Journal of medicinal chemistry 20110127 |
A species-specific approach to the use of non-antimony treatments for cutaneous leishmaniasis. | The American journal of tropical medicine and hygiene 20110105 |
A case of kerion celsi caused by Microsporum gypseum in a boy following dermatoplasty for a scalp wound from a road accident. | Medical mycology 20110101 |
Effects of rifampin and ketoconazole on the pharmacokinetics of nilotinib in healthy participants. | Journal of clinical pharmacology 20110101 |
Effect of the inhibition of CYP3A4 or CYP2D6 on the pharmacokinetics and pharmacodynamics of oxycodone. | European journal of clinical pharmacology 20110101 |
Identification of human liver cytochrome P450 enzymes involved in the metabolism of SCH 530348 (Vorapaxar), a potent oral thrombin protease-activated receptor 1 antagonist. | Drug metabolism and disposition: the biological fate of chemicals 20110101 |
Ketoconazole and miconazole alter potassium homeostasis in Saccharomyces cerevisiae. | Biochimica et biophysica acta 20110101 |
N-(Pyridin-3-yl)benzamides as selective inhibitors of human aldosterone synthase (CYP11B2). | Bioorganic & medicinal chemistry letters 20110101 |
3-[Benzimidazo- and 3-[benzothiadiazoleimidazo-(1,2-c)quinazolin-5-yl]-2H-chromene-2-ones as potent antimicrobial agents. | Bioorganic & medicinal chemistry letters 20110101 |
CYP1A2-mediated biotransformation of cardioactive 2-thienylidene-3,4-methylenedioxybenzoylhydrazine (LASSBio-294) by rat liver microsomes and human recombinant CYP enzymes. | European journal of medicinal chemistry 20110101 |
Fixed drug eruptions induced by cross-reactive imidazoles. | Allergologia et immunopathologia 20110101 |
[Onychomycosis-causing yeasts in four Mexican dermatology centers and their antifungal susceptibility to azolic compounds]. | Revista iberoamericana de micologia 20110101 |
Evaluation of the pharmacokinetic interaction of midazolam with ursodeoxycholic acid, ketoconazole and dexamethasone by brain benzodiazepine receptor occupancy. | The Journal of pharmacy and pharmacology 20110101 |
Inhibitory effects of Phyllanthus amarus and its major lignans on human microsomal cytochrome P450 activities: evidence for CYP3A4 mechanism-based inhibition. | Drug metabolism and pharmacokinetics 20110101 |
In vitro antifungal susceptibility of Candida spp. oral isolates from HIV-positive patients and control individuals. | Brazilian oral research 20110101 |
Patient preferences and treatment safety for uncomplicated vulvovaginal candidiasis in primary health care. | BMC public health 20110101 |
Oropharyngeal histoplasmosis: report of eleven cases and review of the literature. | Revista da Sociedade Brasileira de Medicina Tropical 20110101 |
[Determination of hemolytic activity and in vitro antifungal susceptibility of Trichophyton rubrum clinical strains]. | Mikrobiyoloji bulteni 20110101 |
Disturbance in hemoglobin metabolism and in vivo antimalarial activity of azole antimycotics. | Revista do Instituto de Medicina Tropical de Sao Paulo 20110101 |
Physicochemical characterization and dissolution study of solid dispersions of ketoconazole with nicotinamide. | Chemical & pharmaceutical bulletin 20110101 |
Overexpression of CYP3A4, but not of CYP2D6, promotes hypoxic response and cell growth of Hep3B cells. | Drug metabolism and pharmacokinetics 20110101 |
Cushing syndrome due to ectopic adrenocorticotropic hormone secretion in a 3-year-old child. | Journal of pediatric endocrinology & metabolism : JPEM 20110101 |
[Scedosporium apiospermum disseminated infection in a single lung transplant recipient]. | Revista iberoamericana de micologia 20110101 |
Effectiveness of chronic treatment with ketoconazole in a patient with diabetic Cushing's disease resistant to surgery. | Endokrynologia Polska 20110101 |
Oral cavity eumycetoma. | Revista do Instituto de Medicina Tropical de Sao Paulo 20110101 |
[Immunorehabilitation in patients with paecilomycosis-complicated echinococcosis and asthma]. | Meditsinskaia parazitologiia i parazitarnye bolezni 20110101 |
Trypanosoma cruzi epimastigotes are able to store and mobilize high amounts of cholesterol in reservosome lipid inclusions. | PloS one 20110101 |
Nocardia transvalensis keratitis: an emerging pathology among travelers returning from Asia. | BMC infectious diseases 20110101 |
Prevalence of exocrine pancreatic insufficiency in women with obesity syndrome: assessment by pancreatic fecal elastase 1. | ISRN gastroenterology 20110101 |
Pneumocystis pneumonia during medicamentous treatment of Cushing's syndrome--a description of two cases. | Acta medica (Hradec Kralove) 20110101 |
New aspects in the clinical course of pityriasis versicolor. | Anais brasileiros de dermatologia 20110101 |
Oral antifungal therapy for chronic rhinosinusitis and its subtypes: a systematic review. | International forum of allergy & rhinology 20110101 |
Pilot Study of 15 Patients Receiving a New Treatment Regimen for Androgenic Alopecia: The Effects of Atopy on AGA. | ISRN dermatology 20110101 |
Prophylactic ketoconazole shampoo for tinea capitis in a high-risk pediatric population. | The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG 20110101 |
Optimization of a novel method based on solidification of floating organic droplet by high-performance liquid chromatography for evaluation of antifungal drugs in biological samples. | Talanta 20101215 |
Structural interpretation in composite systems using powder X-ray diffraction: applications of error propagation to the pair distribution function. | Pharmaceutical research 20101201 |
Metabolism and action of proteasome inhibitors in primary human hepatocytes. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
A predictive ligand-based Bayesian model for human drug-induced liver injury. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
Characterisation of zuclopenthixol metabolism by in vitro and therapeutic drug monitoring studies. | Acta psychiatrica Scandinavica 20101201 |
[Probable basidiobolomycosis in a Togolese rural young successfully treated with ketoconazole]. | Bulletin de la Societe de pathologie exotique (1990) 20101201 |
High performance liquid chromatographic assay for the simultaneous determination of midazolam and ketoconazole in plasma. | Journal of pharmaceutical and biomedical analysis 20101102 |
Azole drugs trap cytochrome P450 EryK in alternative conformational states. | Biochemistry 20101102 |
Pharmacokinetics and pharmacodynamics of docetaxel with or without ketoconazole modulation in chemonaive breast cancer patients. | Annals of oncology : official journal of the European Society for Medical Oncology 20101101 |
Effects on plasma corticosterone levels and brain serotonin from interference with methamphetamine-induced corticosterone release in neonatal rats. | Stress (Amsterdam, Netherlands) 20101101 |
Prediction of the intestinal first-pass metabolism of CYP3A substrates in humans using cynomolgus monkeys. | Drug metabolism and disposition: the biological fate of chemicals 20101101 |
Synthesis and biological evaluation of N-antipyrine-4-substituted amino-3-chloromaleimide derivatives. | European journal of medicinal chemistry 20101101 |
Regulation of the hypoxic response in Candida albicans. | Eukaryotic cell 20101101 |
Tumor necrosis factor alpha increases P-glycoprotein expression in a BME-UV in vitro model of mammary epithelial cells. | Biopharmaceutics & drug disposition 20101101 |
Structure and mechanism of the complex between cytochrome P4503A4 and ritonavir. | Proceedings of the National Academy of Sciences of the United States of America 20101026 |
Severe retention hyperkeratosis occurring with Susac syndrome. | Dermatology online journal 20101015 |
Subcutaneous zygomycosis: report of 10 cases from two institutions in North India. | Journal of the European Academy of Dermatology and Venereology : JEADV 20101001 |
Anticandidal effect of Ocimum sanctum essential oil and its synergy with fluconazole and ketoconazole. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20101001 |
Synthesis and CYP24A1 inhibitory activity of (E)-2-(2-substituted benzylidene)- and 2-(2-substituted benzyl)-6-methoxy-tetralones. | European journal of medicinal chemistry 20101001 |
Synthesis and antifungal evaluation of novel triazole derivatives as inhibitors of cytochrome P450 14alpha-demethylase. | European journal of medicinal chemistry 20101001 |
Biorelevant media to simulate fluids in the ascending colon of humans and their usefulness in predicting intracolonic drug solubility. | Pharmaceutical research 20101001 |
Synthesis and antimicrobial activities of novel 1H-dibenzo[a,c]carbazoles from dehydroabietic acid. | European journal of medicinal chemistry 20101001 |
Sources of variability in ketoconazole inhibition of human cytochrome P450 3A in vitro. | Xenobiotica; the fate of foreign compounds in biological systems 20101001 |
Retrospective analysis of the consequences of acid suppressive therapy on ketoconazole efficacy in advanced castration-resistant prostate cancer. | The Annals of pharmacotherapy 20101001 |
[Cardiac safety of cinitapride]. | Gastroenterologia y hepatologia 20101001 |
Presumptive Nocardia spp. infection in a dog treated with cyclosporin and ketoconazole. | New Zealand veterinary journal 20101001 |
Comparative evaluation of ketoconazole-β-cyclodextrin systems prepared by coprecipitation and kneading. | Drug discoveries & therapeutics 20101001 |
Synthesis and evaluation of anti-Toxoplasma gondii and antimicrobial activities of thiosemicarbazides, 4-thiazolidinones and 1,3,4-thiadiazoles. | European journal of medicinal chemistry 20100901 |
A study of cytotoxicity of novel chlorokojic acid derivatives with their antimicrobial and antiviral activities. | European journal of medicinal chemistry 20100901 |
CYP24A1 inhibition enhances the antitumor activity of calcitriol. | Endocrinology 20100901 |
In vitro and in vivo metabolism of a novel cannabinoid-1 receptor inverse agonist, taranabant, in rats and monkeys. | Xenobiotica; the fate of foreign compounds in biological systems 20100901 |
Synthesis and bioassay of aminosulfonyl-1,3,4-oxadiazoles and their interconversion to 1,3,4-thiadiazoles. | European journal of medicinal chemistry 20100901 |
Synthesis and biochemical evaluation of a range of (4-substituted phenyl)sulfonate derivatives of 4-hydroxybenzyl imidazole-based compounds as potent inhibitors of 17alpha-hydroxylase/17,20-lyase (P45017alpha) derived from rat testicular microsomes. | Bioorganic & medicinal chemistry letters 20100901 |
Effects of drug interactions on biotransformation and antiplatelet effect of clopidogrel in vitro. | British journal of pharmacology 20100901 |
Primary cutaneous aspergillosis. | Acta dermato-venereologica 20100901 |
[Metabolism of 3-cyanomethyl-4-methyl-DCK, a new anti-HIV candidate, in human intestinal microsomes]. | Yao xue xue bao = Acta pharmaceutica Sinica 20100901 |
New antifungal peptides. Synthesis, bioassays and initial structure prediction by CD spectroscopy. | Bioorganic & medicinal chemistry letters 20100815 |
Replacement of imidazolyl by pyridyl in biphenylmethylenes results in selective CYP17 and dual CYP17/CYP11B1 inhibitors for the treatment of prostate cancer. | Journal of medicinal chemistry 20100812 |
Ketoconazole in the treatment of central serous chorioretinopathy: a pilot study. | Acta ophthalmologica 20100801 |
The post-antifungal effect (PAFE) of amphotericin B, nystatin, ketoconazole and 5-fluorocytosine and its impact on the colonization traits of Candida glabrata. | Medical mycology 20100801 |
Ketoconazole and rifampin significantly affect the pharmacokinetics, but not the safety or QTc interval, of casopitant, a neurokinin-1 receptor antagonist. | Journal of clinical pharmacology 20100801 |
Infantile hypercalcemia and hypercalciuria: new insights into a vitamin D-dependent mechanism and response to ketoconazole treatment. | The Journal of pediatrics 20100801 |
Antimicrobial activity and a SAR study of some novel benzimidazole derivatives bearing hydrazone moiety. | European journal of medicinal chemistry 20100801 |
In vitro-in vivo extrapolation predicts drug-drug interactions arising from inhibition of codeine glucuronidation by dextropropoxyphene, fluconazole, ketoconazole, and methadone in humans. | The Journal of pharmacology and experimental therapeutics 20100801 |
Advantages of human hepatocyte-derived transformants expressing a series of human cytochrome p450 isoforms for genotoxicity examination. | Toxicological sciences : an official journal of the Society of Toxicology 20100801 |
Differential effects of ketoconazole and primaquine on the pharmacokinetics and tissue distribution of imatinib in mice. | Anti-cancer drugs 20100801 |
A single-dose, crossover, placebo- and moxifloxacin-controlled study to assess the effects of neratinib (HKI-272) on cardiac repolarization in healthy adult subjects. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100801 |
Synthesis and CYP24A1 inhibitory activity of N-(2-(1H-imidazol-1-yl)-2-phenylethyl)arylamides. | Bioorganic & medicinal chemistry 20100715 |
Isopropylidene substitution increases activity and selectivity of biphenylmethylene 4-pyridine type CYP17 inhibitors. | Journal of medicinal chemistry 20100708 |
Synthesis of some N-alkyl substituted urea derivatives as antibacterial and antifungal agents. | European journal of medicinal chemistry 20100701 |
Synthesis and bioassay of pyrrolyl oxazolines and thiazolines. | European journal of medicinal chemistry 20100701 |
Androgen blockade for the treatment of high-flow priapism. | The journal of sexual medicine 20100701 |
Enhancement of the drug susceptibility of a triclabendazole-resistant isolate of Fasciola hepatica using the metabolic inhibitor ketoconazole. | Parasitology research 20100701 |
Cutaneous lymphoid hyperplasia associated with Leishmania panamensis infection. | Acta dermato-venereologica 20100701 |
Validation of a differential in situ perfusion method with mesenteric blood sampling in rats for intestinal drug interaction profiling. | Biopharmaceutics & drug disposition 20100701 |
[Ketoconazole antagonizes the immune and gonadotropic systems in the forced swimming test in male Wistar rats]. | Canadian journal of physiology and pharmacology 20100701 |
Conazoles. | Molecules (Basel, Switzerland) 20100609 |
Effectiveness of cabergoline in monotherapy and combined with ketoconazole in the management of Cushing's disease. | Pituitary 20100601 |
Naftifine-analogues as anti-Trypanosoma cruzi agents. | European journal of medicinal chemistry 20100601 |
CYP3A4 catalytic activity is induced in confluent Huh7 hepatoma cells. | Drug metabolism and disposition: the biological fate of chemicals 20100601 |
Increases in discontinuous rib cartilage and fused carpal bone in rat fetuses exposed to the teratogens, busulfan, acetazolamide, vitamin A, and ketoconazole. | Human & experimental toxicology 20100601 |
A phase I clinical study of high dose ketoconazole plus weekly docetaxel for metastatic castration resistant prostate cancer. | The Journal of urology 20100601 |
The effects of CYP2D6 and CYP3A activities on the pharmacokinetics of immediate release oxycodone. | British journal of pharmacology 20100601 |
Trichodermaketones A-D and 7-O-methylkoninginin D from the marine fungus Trichoderma koningii. | Journal of natural products 20100528 |
Chemical epigenetics alters the secondary metabolite composition of guttate excreted by an atlantic-forest-soil-derived Penicillium citreonigrum. | Journal of natural products 20100528 |
Second generation analogues of the cancer drug clinical candidate tipifarnib for anti-Chagas disease drug discovery. | Journal of medicinal chemistry 20100527 |
Determination of commonly used azole antifungals in various waters and sewage sludge using ultra-high performance liquid chromatography-tandem mass spectrometry. | Journal of chromatography. A 20100521 |
Pharmacophore modeling strategies for the development of novel nonsteroidal inhibitors of human aromatase (CYP19). | Bioorganic & medicinal chemistry letters 20100515 |
Pasireotide alone or with cabergoline and ketoconazole in Cushing's disease. | The New England journal of medicine 20100513 |
Activity of ketoconazole after taxane-based chemotherapy in castration-resistant prostate cancer. | BJU international 20100501 |
Synthesis and the selective antifungal activity of 5,6,7,8-tetrahydroimidazo[1,2-a]pyridine derivatives. | European journal of medicinal chemistry 20100501 |
Oral fingolimod for the treatment of relapsing-remitting multiple sclerosis. | Drugs of today (Barcelona, Spain : 1998) 20100501 |
Sex differences in subacute toxicity and hepatic microsomal metabolism of triptolide in rats. | Toxicology 20100430 |
Structural basis of human CYP51 inhibition by antifungal azoles. | Journal of molecular biology 20100409 |
Probing possible egress channels for multiple ligands in human CYP3A4: a molecular modeling study. | Journal of molecular modeling 20100401 |
Genotoxicity of a freshwater cyanotoxin, cylindrospermopsin, in two human cell lines: Caco-2 and HepaRG. | Environmental and molecular mutagenesis 20100401 |
In vitro investigation of antifungal activity of allicin alone and in combination with azoles against Candida species. | Mycopathologia 20100401 |
Testosterone hydroxylation in bovine liver: enzyme kinetic and inhibition study. | Xenobiotica; the fate of foreign compounds in biological systems 20100401 |
Kinetics of removal of intravenous testosterone pulses in normal men. | European journal of endocrinology 20100401 |
An eco-friendly synthesis and antimicrobial activities of dihydro-2H-benzo- and naphtho-1,3-oxazine derivatives. | European journal of medicinal chemistry 20100401 |
In vitro and in vivo evaluation of oral tablet formulations prepared with ketoconazole and hydroxypropyl-beta-cyclodextrin. | Drug delivery 20100401 |
Potent and selective inhibition of human cytochrome P450 3A4 by seco-pancratistatin structural analogs. | Bioorganic & medicinal chemistry letters 20100401 |
Predictions of metabolic drug-drug interactions using physiologically based modelling: Two cytochrome P450 3A4 substrates coadministered with ketoconazole or verapamil. | Clinical pharmacokinetics 20100401 |
Effects of ketoconazole on the biodistribution and metabolism of [11C]loperamide and [11C]N-desmethyl-loperamide in wild-type and P-gp knockout mice. | Nuclear medicine and biology 20100401 |
[Malassezia folliculitis: 21 cases]. | Annales de dermatologie et de venereologie 20100401 |
Pyrenochaeta keratinophila sp. nov., isolated from an ocular infection in Spain. | Revista iberoamericana de micologia 20100331 |
Phase I clinical trial of the CYP17 inhibitor abiraterone acetate demonstrating clinical activity in patients with castration-resistant prostate cancer who received prior ketoconazole therapy. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100320 |
Phase 1 pharmacokinetic and drug-interaction study of dasatinib in patients with advanced solid tumors. | Cancer 20100315 |
Response to azolic antifungal agents for treating feline sporotrichosis. | The Veterinary record 20100306 |
Current concepts in systemic and topical therapy for superficial mycoses. | Clinics in dermatology 20100304 |
Intralesional sodium stibogluconate alone or its combination with either intramuscular sodium stibogluconate or oral ketoconazole in the treatment of localized cutaneous leishmaniasis: a comparative study. | Journal of the European Academy of Dermatology and Venereology : JEADV 20100301 |
Potent in vitro inhibition of CYP3A4 and P-glycoprotein by Rhodiola rosea. | Planta medica 20100301 |
Synthesis, characterization and biocidal activity of new organotin complexes of 2-(3-oxocyclohex-1-enyl)benzoic acid. | European journal of medicinal chemistry 20100301 |
Antimicrobial study of newly synthesized 6-substituted indolo[1,2-c]quinazolines. | European journal of medicinal chemistry 20100301 |
Pulmonary toxicity and metabolic activation of dauricine in CD-1 mice. | The Journal of pharmacology and experimental therapeutics 20100301 |
Composition optimization and stability testing of a parenteral antifungal solution based on a ternary solvent system. | AAPS PharmSciTech 20100301 |
Comparative evaluation of ketoconazole tablet and topical ketoconazole 2% in orabase in treatment of Candida-infected denture stomatitis. | The journal of contemporary dental practice 20100301 |
Effect of ketoconazole on the pharmacokinetics of udenafil in healthy Korean subjects. | British journal of clinical pharmacology 20100301 |
Absorption barriers in the rat intestinal mucosa: 2. Application of physiologically based mathematical models to quantify mechanisms of drug permeation and metabolism. | Journal of pharmaceutical sciences 20100201 |
Quantitative prediction and clinical observation of a CYP3A inhibitor-based drug-drug interactions with MLN3897, a potent C-C chemokine receptor-1 antagonist. | The Journal of pharmacology and experimental therapeutics 20100201 |
Ketoconazole enantiomer for the treatment of diabetes mellitus. | Expert opinion on investigational drugs 20100201 |
Use of antifungal agents for oral candidiasis: results of a national survey. | International journal of dental hygiene 20100201 |
Sulfonamide-1,2,4-thiadiazole derivatives as antifungal and antibacterial agents: synthesis, biological evaluation, lipophilicity, and conformational studies. | Chemical & pharmaceutical bulletin 20100201 |
The pharmacokinetics of ketoconazole and its effects on the pharmacokinetics of midazolam and fentanyl in dogs. | Journal of veterinary pharmacology and therapeutics 20100201 |
Cutaneous malasseziasis: four case reports of atypical dermatitis and onychomycosis caused by Malassezia. | International journal of dermatology 20100201 |
Adrenocorticotrophic hormone (ACTH) responsiveness to ghrelin increases after 6 months of ketoconazole use in patients with Cushing's disease: comparison with GH-releasing peptide-6 (GHRP-6). | Clinical endocrinology 20100101 |
In young men, a moderate inhibition of testosterone synthesis capacity is only partly compensated by increased activity of the pituitary and the hypothalamus. | Clinical endocrinology 20100101 |
Synergistic anti-candidal activity of tetrandrine on ketoconazole: an experimental study. | Planta medica 20100101 |
Identification of the human cytochrome P450 enzymes involved in the two oxidative steps in the bioactivation of clopidogrel to its pharmacologically active metabolite. | Drug metabolism and disposition: the biological fate of chemicals 20100101 |
The application of in vitro technologies to study the metabolism of the androgenic/anabolic steroid stanozolol in the equine. | Steroids 20100101 |
Novel 4-thiazolidinone derivatives as potential antifungal and antibacterial drugs. | Bioorganic & medicinal chemistry 20100101 |
Screening of antimycotics in Swedish sewage treatment plants--waters and sludge. | Water research 20100101 |
CYP3A catalyses schizandrin biotransformation in human, minipig and rat liver microsomes. | Xenobiotica; the fate of foreign compounds in biological systems 20100101 |
Candida albicans enhances experimental hepatic melanoma metastasis. | Clinical & experimental metastasis 20100101 |
Esthesioneuroblastoma (Olfactory Neuroblastoma) with Ectopic ACTH Syndrome: a multidisciplinary case presentation from the Joan Karnell cancer center of Pennsylvania Hospital. | The oncologist 20100101 |
Hormonal therapy for acne: why not as first line therapy? facts and controversies. | Clinics in dermatology 20100101 |
[Acquired pigmented lesion of the foot]. | Annales de dermatologie et de venereologie 20100101 |
Everolimus versus azathioprine in a cyclosporine and ketoconazole-based immunosuppressive therapy in kidney transplant: 3-year follow-up of an open-label, prospective, cohort, comparative clinical trial. | Transplantation proceedings 20100101 |
Effectiveness and cost of replacing a calcineurin inhibitor with sirolimus to slow the course of chronic kidney disease in renal allografts. | Transplantation proceedings 20100101 |
[Echinococcosis complicated by paecilomycosis]. | Meditsinskaia parazitologiia i parazitarnye bolezni 20100101 |
Medical therapy of Cushing's disease: where are we now? | Frontiers of hormone research 20100101 |
Diagnostic and therapeutic challenge in the management of a patient with ectopic adrenocorticotropin secretion. | Journal of endocrinological investigation 20100101 |
The sensitivity and specificity of potassium hydroxide smear and fungal culture relative to clinical assessment in the evaluation of tinea pedis: a pooled analysis. | Dermatology research and practice 20100101 |
Colletotrichum graminicola keratitis: first case report from India. | Indian journal of ophthalmology 20100101 |
Management of diabetes mellitus in Cushing's syndrome. | Neuroendocrinology 20100101 |
Management of dyslipidemia in Cushing's syndrome. | Neuroendocrinology 20100101 |
Medical treatment of Cushing's syndrome: adrenal-blocking drugs and ketaconazole. | Neuroendocrinology 20100101 |
Evaluation of terfenadine and ketoconazole-induced QT prolongation in conscious telemetered guinea pigs. | Pharmacological reports : PR 20100101 |
High-performance thin-layer chromatographic determination of ketoconazole in pharmaceutical formulations. | Journal of cosmetic science 20100101 |
A noninferiority clinical trial comparing fluconazole and ketoconazole in combination with cephalexin for the treatment of dogs with Malassezia dermatitis. | Veterinary therapeutics : research in applied veterinary medicine 20100101 |
Sporothrix schenckii associated with armadillo hunting in Southern Brazil: epidemiological and antifungal susceptibility profiles. | Revista da Sociedade Brasileira de Medicina Tropical 20100101 |
Use of granisetron transdermal system in the prevention of chemotherapy-induced nausea and vomiting: a review. | Cancer management and research 20100101 |
Novel medical treatment of pituitary adrenocorticotropic hormone-dependent hypercortisolism: a case study. | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20100101 |
Childhood acute generalized exanthematous pustulosis induced by oral ketoconazole. | Acta dermatovenerologica Croatica : ADC 20100101 |
Antioxidant and antimicrobial activity of some lichen species. | Mikrobiologiia 20100101 |
[White piedra in a pediatric patient: a case report]. | Revista iberoamericana de micologia 20091231 |
Rapid LC-MS drug metabolite profiling using microsomal enzyme bioreactors in a parallel processing format. | Analytical chemistry 20091215 |
Simultaneous determination of five systemic azoles in plasma by high-performance liquid chromatography with ultraviolet detection. | Journal of pharmaceutical and biomedical analysis 20091205 |
Synergistic anticandidal activity of xanthorrhizol in combination with ketoconazole or amphotericin B. | FEMS yeast research 20091201 |
Inhibition and stimulation of intestinal and hepatic CYP3A activity: studies in humanized CYP3A4 transgenic mice using triazolam. | Drug metabolism and disposition: the biological fate of chemicals 20091201 |
Side chain azasteroids and thiasteroids as sterol methyltransferase inhibitors in ergosterol biosynthesis. | Bioorganic & medicinal chemistry 20091201 |
Synthesis and biological activities of new substituted thiazoline-quinoline derivatives. | Acta pharmaceutica (Zagreb, Croatia) 20091201 |
Drugs in the medical treatment of Cushing's syndrome. | Expert opinion on emerging drugs 20091201 |
The effects of ketoconazole and rifampicin on the pharmacokinetics of mirodenafil in healthy Korean male volunteers: an open-label, one-sequence, three-period, three-treatment crossover study. | Clinical therapeutics 20091201 |
Rhabdomyomatous mesenchymal hamartoma: clinical overview and report of a case with spontaneous regression. | The West Indian medical journal 20091201 |
Strategy of accelerated method development for high-throughput bioanalytical assays using ultra high-performance liquid chromatography coupled with mass spectrometry. | Analytical chemistry 20091115 |
Phase II study of androgen synthesis inhibition with ketoconazole, hydrocortisone, and dutasteride in asymptomatic castration-resistant prostate cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20091115 |
Influence of quinidine, cimetidine, and ketoconazole on the enantioselective pharmacokinetics and metabolism of metoprolol in rats. | Chirality 20091101 |
Synthesis of some novel pyrazolo[3,4-b]pyridine and pyrazolo[3,4-d]pyrimidine derivatives bearing 5,6-diphenyl-1,2,4-triazine moiety as potential antimicrobial agents. | European journal of medicinal chemistry 20091101 |
Synthesis, antimicrobial and antioxidant activities of substituted pyrazoles, isoxazoles, pyrimidine and thioxopyrimidine derivatives. | European journal of medicinal chemistry 20091101 |
Roles of different CYP enzymes in the formation of specific fluvastatin metabolites by human liver microsomes. | Basic & clinical pharmacology & toxicology 20091101 |
Different effects of ketoconazole on the stereoselective first-pass metabolism of R/S-verapamil in the intestine and the liver: important for the mechanistic understanding of first-pass drug-drug interactions. | Drug metabolism and disposition: the biological fate of chemicals 20091101 |
Partial restoration of GH responsiveness to ghrelin in Cushing's disease after 6 months of ketoconazole treatment: comparison with GHRP-6 and GHRH. | European journal of endocrinology 20091101 |
Synthesis, Raman, FT-IR, NMR spectroscopic characterization, antimicrobial activity, cytotoxicity and DNA binding of new mixed aza-oxo-thia macrocyclic compounds. | European journal of medicinal chemistry 20091101 |
Evaluation of drug-polymer miscibility in amorphous solid dispersion systems. | Pharmaceutical research 20091101 |
5-Nitrofuranes and 5-nitrothiophenes with anti-Trypanosoma cruzi activity and ability to accumulate squalene. | Bioorganic & medicinal chemistry 20091101 |
Deactivation of anti-cancer drug letrozole to a carbinol metabolite by polymorphic cytochrome P450 2A6 in human liver microsomes. | Xenobiotica; the fate of foreign compounds in biological systems 20091101 |
In vitro antimalarial interactions between mefloquine and cytochrome P450 inhibitors. | Acta tropica 20091001 |
Superficial distribution and identification of antifungal/antimicrobial agents on a modified tissue conditioner by SEM-EDS microanalysis: a preliminary study. | Journal of prosthodontics : official journal of the American College of Prosthodontists 20091001 |
Ketoconazole-induced JNK phosphorylation and subsequent cell death via apoptosis in human osteosarcoma cells. | Toxicology in vitro : an international journal published in association with BIBRA 20091001 |
Ketoconazole and prednisone to prevent recurrent ischemic priapism. | The Journal of urology 20091001 |
Structure-activity studies on seco-pancratistatin analogs: potent inhibitors of human cytochrome P450 3A4. | Bioorganic & medicinal chemistry letters 20091001 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. | Nature chemical biology 20091001 |
Biliary excretion of technetium-99m-sestamibi in wild-type dogs and in dogs with intrinsic (ABCB1-1Delta mutation) and extrinsic (ketoconazole treated) P-glycoprotein deficiency. | Journal of veterinary pharmacology and therapeutics 20091001 |
Activity of dutasteride plus ketoconazole in castration-refractory prostate cancer after progression on ketoconazole alone. | Clinical genitourinary cancer 20091001 |
In vitro and in vivo evaluation of the inhibition potential of risperidone toward clozapine biotransformation. | British journal of clinical pharmacology 20091001 |
A novel class of highly potent multidrug resistance reversal agents: disubstituted adamantyl derivatives. | Bioorganic & medicinal chemistry letters 20090915 |
Transfer of rolf S3-S4 linker to HERG eliminates activation gating but spares inactivation. | Biophysical journal 20090902 |
The amino acid residues of transmembrane helix 5 of multidrug resistance protein CaCdr1p of Candida albicans are involved in substrate specificity and drug transport. | Biochimica et biophysica acta 20090901 |
The arachidonic acid epoxygenase is a component of the signaling mechanisms responsible for VEGF-stimulated angiogenesis. | Archives of biochemistry and biophysics 20090901 |
Prednisone reduces ketoconazole-induced skeletal defects in rat fetuses. | Archives of toxicology 20090901 |
In vitro synergistic effects of antituberculous drugs plus antifungals against Coccidioides posadasii. | International journal of antimicrobial agents 20090901 |
Infectious keratitis caused by Aspergillus tubingensis. | Cornea 20090901 |
Aetiological treatment with itraconazole or ketoconazole in individuals with Trypanosoma cruzi/HIV co-infection. | Annals of tropical medicine and parasitology 20090901 |
The effect on sotrastaurin pharmacokinetics of strong CYP3A inhibition by ketoconazole. | British journal of clinical pharmacology 20090901 |
Inhibitory effects of ketoconazole, cimetidine and erythromycin on hepatic CYP3A activities in cats. | The Journal of veterinary medical science 20090901 |
Synthesis and biochemical evaluation of a range of sulfonated derivatives of 4-hydroxybenzyl imidazole as highly potent inhibitors of rat testicular 17alpha-hydroxylase/17,20-lyase (P-450(17alpha)). | Bioorganic & medicinal chemistry letters 20090815 |
Electron paramagnetic resonance method for the quantitative assay of ketoconazole in pharmaceutical preparations. | Analytical chemistry 20090815 |
Differential effect of Shenmai injection, a herbal preparation, on the cytochrome P450 3A-mediated 1'-hydroxylation and 4-hydroxylation of midazolam. | Chemico-biological interactions 20090814 |
Identification and chromosomal localization of one locus of Leishmania (L.) major related with resistance to itraconazole. | Parasitology research 20090801 |
Spondylodiscitis due to an emergent fungal pathogen: Blastoschizomyces capitatus, a case report and review of the literature. | Rheumatology international 20090801 |
Mono and bis-6-arylbenzimidazo[1,2-c]quinazolines: a new class of antimicrobial agents. | European journal of medicinal chemistry 20090801 |
Synthesis and antimultidrug resistance evaluation of icariin and its derivatives. | Bioorganic & medicinal chemistry letters 20090801 |
About the role of enantioselective selector-selectand interactions and the mobilities of diastereomeric associates in enantiomer separations using CE. | Electrophoresis 20090801 |
Dermatomycosis in a pet inland bearded dragon (Pogona vitticeps) caused by a Chrysosporium species related to Nannizziopsis vriesii. | Veterinary dermatology 20090801 |
Metabolism of loratadine and further characterization of its in vitro metabolites. | Drug metabolism letters 20090801 |
Revisiting the metabolism of ketoconazole using accurate mass. | Drug metabolism letters 20090801 |
Side chain flexibilities in the human ether-a-go-go related gene potassium channel (hERG) together with matched-pair binding studies suggest a new binding mode for channel blockers. | Journal of medicinal chemistry 20090723 |
Hypokalemia, metabolic alkalosis, and hypertension in a lung cancer patient. | Kidney international 20090701 |
Nonlinear stereoselective pharmacokinetics of ketoconazole in rat after administration of racemate. | Chirality 20090701 |
In vitro inhibition of CYP3A4 by herbal remedies frequently used by cancer patients. | Phytotherapy research : PTR 20090701 |
Novel CYP17 inhibitors: synthesis, biological evaluation, structure-activity relationships and modelling of methoxy- and hydroxy-substituted methyleneimidazolyl biphenyls. | European journal of medicinal chemistry 20090701 |
Limited sampling strategy in rats to predict the inhibited activities of hepatic CYP3A. | Laboratory animals 20090701 |
Steroidogenesis inhibitors alter but do not eliminate androgen synthesis mechanisms during progression to castration-resistance in LNCaP prostate xenografts. | The Journal of steroid biochemistry and molecular biology 20090701 |
Regioselective synthesis and biological evaluation of bis(indolyl)methane derivatized 1,4-disubstituted 1,2,3-bistriazoles as anti-infective agents. | Bioorganic & medicinal chemistry letters 20090701 |
Single-center experience with cyclosporine for treatment of idiopathic minimal change nephrotic syndrome in children. | Iranian journal of kidney diseases 20090701 |
In vitro response of cutaneous mycosis fungal agents to the most widely used systemic antifungals in dermatology. | Anais brasileiros de dermatologia 20090701 |
Drug-drug interaction prediction assessment. | Journal of biopharmaceutical statistics 20090701 |
Cytotoxicity of ginkgolic acid in HepG2 cells and primary rat hepatocytes. | Toxicology letters 20090622 |
Selective cytochrome P450 3A4 inhibitory activity of Amaryllidaceae alkaloids. | Bioorganic & medicinal chemistry letters 20090615 |
An inhibition study of beauvericin on human and rat cytochrome P450 enzymes and its pharmacokinetics in rats. | Journal of enzyme inhibition and medicinal chemistry 20090601 |
Neurocryptococcosis in a 10-year-old immunocompetent girl. | Acta neurochirurgica 20090601 |
Evaluation of drug-drug interactions with fesoterodine. | European journal of clinical pharmacology 20090601 |
CYP3A5*1/*3 genotype influences the blood concentration of tacrolimus in response to metabolic inhibition by ketoconazole. | Pharmacogenetics and genomics 20090601 |
Effect of ketoconazole on the pharmacokinetic profile of ambrisentan. | Journal of clinical pharmacology 20090601 |
Growth inhibitory action of ebselen on fluconazole-resistant Candida albicans: role of the plasma membrane H+-ATPase. | Microbial drug resistance (Larchmont, N.Y.) 20090601 |
Bulky 1,4-benzoxazine derivatives with antifungal activity. | Bioorganic & medicinal chemistry 20090601 |
Therapies for pediatric seborrheic dermatitis. | Pediatric annals 20090601 |
Randomised controlled trial of the treatment of pastern dermatitis with a formulation containing kunzea oil. | The Veterinary record 20090516 |
Synthesis and bioassay of a new class of heterocycles pyrrolyl oxadiazoles/thiadiazoles/triazoles. | European journal of medicinal chemistry 20090501 |
Synthesis and anti-microbial screening of some Schiff bases of 3-amino-6,8-dibromo-2-phenylquinazolin-4(3H)-ones. | European journal of medicinal chemistry 20090501 |
Synthesis, antimicrobial and cytotoxic activities of some 5-arylidene-4-thioxo-thiazolidine-2-ones. | European journal of medicinal chemistry 20090501 |
Synthesis, antimicrobial evaluation and QSAR study of some 3-hydroxypyridine-4-one and 3-hydroxypyran-4-one derivatives. | European journal of medicinal chemistry 20090501 |
Design, synthesis, and biological evaluation of novel triazole derivatives as inhibitors of cytochrome P450 14alpha-demethylase. | European journal of medicinal chemistry 20090501 |
Electronic, Raman and FT-IR spectral investigations of the charge transfer interactions between ketoconazole and povidone drugs with iodine. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20090501 |
Novel secondary hormonal therapy in advanced prostate cancer: an update. | Current opinion in urology 20090501 |
Identification of quinone methide metabolites of dauricine in human liver microsomes and in rat bile. | Chemical research in toxicology 20090501 |
Antimicrobial ambiguine isonitriles from the cyanobacterium Fischerella ambigua. | Journal of natural products 20090501 |
Ketoconazole retains activity in patients with docetaxel-refractory prostate cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20090501 |
New acyclic nucleosides analogues as potential analgesic, anti-inflammatory, anti-oxidant and anti-microbial derived from pyrimido[4,5-b]quinolines. | European journal of medicinal chemistry 20090401 |
Contact allergy to ketoconazole cross-sensitive to miconazole. | Clinical and experimental dermatology 20090401 |
In vitro activities of retigeric acid B alone and in combination with azole antifungal agents against Candida albicans. | Antimicrobial agents and chemotherapy 20090401 |
Exploratory study on the clinical and mycological effectiveness of a herbal medicinal product from Solanum chrysotrichum in patients with Candida yeast-associated vaginal infection. | Planta medica 20090401 |
Relative contributions of the Candida albicans ABC transporters Cdr1p and Cdr2p to clinical azole resistance. | Antimicrobial agents and chemotherapy 20090401 |
Effect of different durations of ketoconazole dosing on the single-dose pharmacokinetics of midazolam: shortening the paradigm. | Journal of clinical pharmacology 20090401 |
[Treatment of Cushing's disease with ketoconazole]. | Anales de pediatria (Barcelona, Spain : 2003) 20090401 |
In vitro metabolism and inhibitory effects of pranlukast in human liver microsomes. | Biological & pharmaceutical bulletin 20090401 |
Effects of ketoconazole and carbamazepine on lapatinib pharmacokinetics in healthy subjects. | British journal of clinical pharmacology 20090401 |
Ketoconazole allergy. | Clinics (Sao Paulo, Brazil) 20090401 |
[Enzyme kinetics of ligustilide metabolism in rat liver microsomes]. | Yao xue xue bao = Acta pharmaceutica Sinica 20090401 |
Direct antifungal susceptibility testing of positive Candida blood cultures by sensititre YeastOne. | The new microbiologica 20090401 |
Steroidogenesis-disrupting compounds can be effectively studied for major fertility-related endpoints using in vitro cultured mouse follicles. | Toxicology letters 20090328 |
Rational modification of a candidate cancer drug for use against Chagas disease. | Journal of medicinal chemistry 20090326 |
Design, synthesis, and biological evaluation of novel 1-(1H-1,2,4-triazole-1-yl)-2-(2,4-difluorophenyl)-3-substituted benzylamino-2-propanols. | Bioorganic & medicinal chemistry letters 20090315 |
Relation between lipophilicity of alkyl gallates and antifungal activity against yeasts and filamentous fungi. | Bioorganic & medicinal chemistry letters 20090315 |
Modulation of the antifungal activity of new medicinal plant extracts active on Candida glabrata by the major transporters and regulators of the pleiotropic drug-resistance network in Saccharomyces cerevisiae. | Microbial drug resistance (Larchmont, N.Y.) 20090301 |
Pharmacological interactions of anti-microbial agents in odontology. | Medicina oral, patologia oral y cirugia bucal 20090301 |
Quantitative evaluation of pharmacokinetic inhibition of CYP3A substrates by ketoconazole: a simulation study. | Journal of clinical pharmacology 20090301 |
The need for multiple doses of 400 mg ketoconazole as a precipitant inhibitor of a CYP3A substrate in an in vivo drug-drug interaction study. | Journal of clinical pharmacology 20090301 |
A single-center, open-label, one-sequence study of dalcetrapib coadministered with ketoconazole, and an in vitro study of the S-methyl metabolite of dalcetrapib. | Clinical therapeutics 20090301 |
Flexible structure of cytochrome P450: promiscuity of ligand binding in the CYP3A4 heme pocket. | Anticancer research 20090301 |
Ketoconazole treatment for Cushing syndrome in McCune-Albright syndrome. | The Journal of pediatrics 20090301 |
Aqueous solvent system for the solubilization of azole compounds. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090215 |
Rhinosporidiosis in a dog native to the UK. | The Veterinary record 20090214 |
CYP1A1 induction and CYP3A4 inhibition by the fungicide imazalil in the human intestinal Caco-2 cells-comparison with other conazole pesticides. | Toxicology letters 20090210 |
Clearance and clearance inhibition of the HIV-1 protease inhibitors ritonavir and saquinavir in sandwich-cultured rat hepatocytes and rat microsomes. | Toxicology in vitro : an international journal published in association with BIBRA 20090201 |
Synthesis and antifungal activity of 1,2,3-triazole containing fluconazole analogues. | Bioorganic & medicinal chemistry letters 20090201 |
Ketoconazole increases fingolimod blood levels in a drug interaction via CYP4F2 inhibition. | Journal of clinical pharmacology 20090201 |
A new probabilistic rule for drug-dug interaction prediction. | Journal of pharmacokinetics and pharmacodynamics 20090201 |
Inhibition of cytochrome P450 activity enhances the systemic availability of triclabendazole metabolites in sheep. | Journal of veterinary pharmacology and therapeutics 20090201 |
Pharmacokinetic interaction between efavirenz and ketoconazole in rats. | Xenobiotica; the fate of foreign compounds in biological systems 20090201 |
Effects of oral posaconazole on the pharmacokinetic properties of oral and intravenous midazolam: a phase I, randomized, open-label, crossover study in healthy volunteers. | Clinical therapeutics 20090201 |
Clinical practice. Seborrheic dermatitis. | The New England journal of medicine 20090122 |
Novel non-active site inhibitor of Cryptosporidium hominis TS-DHFR identified by a virtual screen. | Bioorganic & medicinal chemistry letters 20090115 |
Synthesis, trypanocidal activity and docking studies of novel quinoxaline-N-acylhydrazones, designed as cruzain inhibitors candidates. | Bioorganic & medicinal chemistry 20090115 |
Synthesis, Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of mixed aza-oxo-thia macrocyclic compounds. | European journal of medicinal chemistry 20090101 |
An open, randomized, prospective, comparative study of topical pimecrolimus 1% cream and topical ketoconazole 2% cream in the treatment of seborrheic dermatitis. | The Journal of dermatological treatment 20090101 |
Decreased oral absorption of cyclosporine A after liver ischemia-reperfusion injury in rats: the contribution of CYP3A and P-glycoprotein to the first-pass metabolism in intestinal epithelial cells. | The Journal of pharmacology and experimental therapeutics 20090101 |
Effect of oral ketoconazole on oral and intravenous pharmacokinetics of simvastatin and its acid in cynomolgus monkeys. | Drug metabolism and disposition: the biological fate of chemicals 20090101 |
Fungistatic effects of optical brightener 220 against Trichophyton tonsurans, Aspergillus fumigatus and Candida albicans. | The Journal of dermatological treatment 20090101 |
Assessment of the CYP3A-mediated drug interaction potential of anacetrapib, a potent cholesteryl ester transfer protein (CETP) inhibitor, in healthy volunteers. | Journal of clinical pharmacology 20090101 |
Inhibition of CYP3A4 expression by ketoconazole is mediated by the disruption of pregnane X receptor, steroid receptor coactivator-1, and hepatocyte nuclear factor 4alpha interaction. | Pharmacogenetics and genomics 20090101 |
Etomidate infusion in the critical care setting for suppressing the acute phase of Cushing's syndrome. | Anesthesia and analgesia 20090101 |
Glucocorticoid inhibition in the treatment of depression: can we think outside the endocrine hypothalamus? | Depression and anxiety 20090101 |
A study to evaluate the efficacy and safety of oral fluconazole in the treatment of tinea versicolor. | Mymensingh medical journal : MMJ 20090101 |
[Fungicidal activity of liranaftate against dermatophytes]. | Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20090101 |
In vitro susceptibility testing of dermatophytes isolated in Goiania, Brazil, against five antifungal agents by broth microdilution method. | Revista do Instituto de Medicina Tropical de Sao Paulo 20090101 |
Alterations in growth and branching of Neurospora crassa caused by sub-inhibitory concentrations of antifungal agents. | Revista Argentina de microbiologia 20090101 |
Tinea capitis due to Trichophyton soudanense in Chicago, Illinois: report of a case. | Pediatric dermatology 20090101 |
Bioequivalence studies and sugar-based excipients effects on the properties of new generic ketoconazole tablets formulations and stability evaluation by using direct compression method. | Pharmaceutical development and technology 20090101 |
High-throughput fluorescence assay of cytochrome P450 3A4. | Nature protocols 20090101 |
Determination of ketoconazole in capsules by high-performance liquid chromatography and microbiological assay. | Journal of AOAC International 20090101 |
Two-year experience with tacrolimus in renal transplantation after late conversion from cyclosporine therapy. | Transplantation proceedings 20090101 |
Ketoconazole inhibits the growth and development of Ichthyophonus sp. (Mesomycetozoa) in vitro. | The Journal of eukaryotic microbiology 20090101 |
[Guidelines for diagnosis and treatment of mucocutaneous candidiasis]. | Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20090101 |
Prediction of drug-drug interactions based on time-dependent inhibition from high throughput screening of cytochrome P450 3A4 inhibition. | Drug metabolism and pharmacokinetics 20090101 |
Effect of the CYP3A inhibitor ketoconazole on the pharmacokinetics and pharmacodynamics of bortezomib in patients with advanced solid tumors: a prospective, multicenter, open-label, randomized, two-way crossover drug-drug interaction study. | Clinical therapeutics 20090101 |
[Nizoral - an effective and affordable drug to treat vaginal candidiasis ]. | Akusherstvo i ginekologiia 20090101 |
In vivo active aldosterone synthase inhibitors with improved selectivity: lead optimization providing a series of pyridine substituted 3,4-dihydro-1H-quinolin-2-one derivatives. | Journal of medicinal chemistry 20081225 |
Phase III trial of androgen ablation with or without three cycles of systemic chemotherapy for advanced prostate cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20081220 |
Use of ketoconazole to treat dogs with pituitary-dependent hyperadrenocorticism: 48 cases (1994-2007). | Journal of the American Veterinary Medical Association 20081215 |
Biopositive effects of low-dose UVB on epidermis: coordinate upregulation of antimicrobial peptides and permeability barrier reinforcement. | The Journal of investigative dermatology 20081201 |
The combination of chemical and antibody inhibitors for superior P450 3A inhibition in reaction phenotyping studies. | Drug metabolism and disposition: the biological fate of chemicals 20081201 |
Effects of an ergosterol synthesis inhibitor on gene transcription of terpenoid biosynthesis in Blakeslea trispora. | Current microbiology 20081201 |
Confirmation that cytochrome P450 2C8 (CYP2C8) plays a minor role in (S)-(+)- and (R)-(-)-ibuprofen hydroxylation in vitro. | Drug metabolism and disposition: the biological fate of chemicals 20081201 |
A double transgenic mouse model expressing human pregnane X receptor and cytochrome P450 3A4. | Drug metabolism and disposition: the biological fate of chemicals 20081201 |
Interindividual variation in relative CYP1A2/3A4 phenotype influences susceptibility of clozapine oxidation to cytochrome P450-specific inhibition in human hepatic microsomes. | Drug metabolism and disposition: the biological fate of chemicals 20081201 |
Bone-targeted therapy: phase II study of strontium-89 in combination with alternating weekly chemohormonal therapies for patients with advanced androgen-independent prostate cancer. | American journal of clinical oncology 20081201 |
Susceptibility to voriconazole, fluconazole, and ketoconazole of yeast isolated from patients with hematological malignancies. | Journal of chemotherapy (Florence, Italy) 20081201 |
Presystemic elimination of budesonide in man when administered locally at different levels in the gut, with and without local inhibition by ketoconazole. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20081115 |
Comparative efficacy and tolerability of Ketomousse (ketoconazole foam 1%) and ketoconazole cream 2% in the treatment of pityriasis versicolor: results of a prospective, multicentre, randomised study. | Mycoses 20081101 |
Widespread, chronic, and fluconazole-resistant Trichophyton rubrum infection in an immunocompetent patient. | Mycoses 20081101 |
Effect of commonly used herbicides on the virulence factor CDR1 in Candida albicans. | Environmental toxicology and chemistry 20081101 |
Hypocortisolemic clamp unmasks jointly feedforward- and feedback-dependent control of overnight ACTH secretion. | European journal of endocrinology 20081101 |
Effect of single and repeated doses of ketoconazole on the pharmacokinetics of roflumilast and roflumilast N-oxide. | Journal of clinical pharmacology 20081101 |
Pharmacokinetics of the oral direct renin inhibitor aliskiren in combination with digoxin, atorvastatin, and ketoconazole in healthy subjects: the role of P-glycoprotein in the disposition of aliskiren. | Journal of clinical pharmacology 20081101 |
Re: Oral ketoconazole for prevention of postoperative penile erection: a placebo controlled, randomized, double-blind trial: B. J. DeCastro, R. A. Costabile, L. P. McMann and A. C. Peterson. J Urol 2008; 179: 1930-1932. | The Journal of urology 20081101 |
1alpha,25-Dihydroxyvitamin D hydroxylase in adipocytes. | The Journal of steroid biochemistry and molecular biology 20081101 |
Human CYP3A4-introduced HepG2 cells: in vitro screening system of new chemicals for the evaluation of CYP3A4-inhibiting activity. | Xenobiotica; the fate of foreign compounds in biological systems 20081101 |
Monodictyochromes A and B, dimeric xanthone derivatives from the marine algicolous fungus Monodictys putredinis. | Journal of natural products 20081101 |
In vitro CYP3A4 metabolism: inhibition by Echinacea purpurea and choice of substrate for the evaluation of herbal inhibition. | Basic & clinical pharmacology & toxicology 20081101 |
Influence of quinidine, fluvoxamine, and ketoconazole on the enantioselective pharmacokinetics of citalopram in rats. | Canadian journal of physiology and pharmacology 20081101 |
Histopathological effect of ketoconazole on rat placenta. | The Journal of veterinary medical science 20081101 |
[Mixed vaginitis prevalence in Latin-American women, according to physician perception. Preference, effectiveness and security of clindamycin plus ketoconazole]. | Ginecologia y obstetricia de Mexico 20081101 |
Activation of the proopiomelanocortin gene with ketoconazole as a treatment for Parkinson's disease: a new hypothesis. | Annals of the New York Academy of Sciences 20081101 |
Ketoconazole increases the plasma levels of ivermectin in sheep. | Veterinary parasitology 20081020 |
Novel aldosterone synthase inhibitors with extended carbocyclic skeleton by a combined ligand-based and structure-based drug design approach. | Journal of medicinal chemistry 20081009 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. | Journal of medicinal chemistry 20081009 |
Condensed bridgehead nitrogen heterocyclic system: synthesis and pharmacological activities of 1,2,4-triazolo-[3,4-b]-1,3,4-thiadiazole derivatives of ibuprofen and biphenyl-4-yloxy acetic acid. | European journal of medicinal chemistry 20081001 |
Effect of coadministration of ketoconazole, a strong CYP3A4 inhibitor, on pharmacokinetics and tolerability of motesanib diphosphate (AMG 706) in patients with advanced solid tumors. | Investigational new drugs 20081001 |
Maraviroc: in vitro assessment of drug-drug interaction potential. | British journal of clinical pharmacology 20081001 |
Differential azole antifungal efficacies contrasted using a Saccharomyces cerevisiae strain humanized for sterol 14 alpha-demethylase at the homologous locus. | Antimicrobial agents and chemotherapy 20081001 |
Inhibition of hERG channel trafficking: an under-explored mechanism for drug-induced QT prolongation. | ChemMedChem 20081001 |
Management of recurrent and refractory Cushing disease. | Nature clinical practice. Endocrinology & metabolism 20081001 |
Medical treatments for male and female pattern hair loss. | Journal of the American Academy of Dermatology 20081001 |
Ocular pharmacokinetics of topically-applied ketoconazole solution containing hydroxypropyl beta-cyclodextrin to rabbits. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20081001 |
Evidence for the mechanism of action of the antifungal phytolaccoside B isolated from Phytolacca tetramera Hauman. | Journal of natural products 20081001 |
[Synergy between ajoene and ketoconazole in isolates of Microsporum canis. A preliminary study using fractional inhibitory concentration technique (FIC)]. | Revista iberoamericana de micologia 20080930 |
Screening of herbal constituents for aromatase inhibitory activity. | Bioorganic & medicinal chemistry 20080915 |
Enamines as novel antibacterials and their structure-activity relationships. | European journal of medicinal chemistry 20080901 |
Differential enzymatic reductions governing the differential hypoxia-selective cytotoxicities of phenazine 5,10-dioxides. | Chemical research in toxicology 20080901 |
NO-donors. Part 17: Synthesis and antimicrobial activity of novel ketoconazole-NO-donor hybrid compounds. | Bioorganic & medicinal chemistry 20080901 |
In vitro antifungal activity of polyfunctionalized 2-(hetero)arylquinolines prepared through imino Diels-Alder reactions. | Bioorganic & medicinal chemistry 20080901 |
Steroidal saponins from the roots of Smilax aspera subsp. mauritanica. | Chemical & pharmaceutical bulletin 20080901 |
Responses of the medaka HPG axis PCR array and reproduction to prochloraz and ketoconazole. | Environmental science & technology 20080901 |
Comparison of the anti-inflammatory activities of imidazole antimycotics in relation to molecular structure. | Chemical biology & drug design 20080901 |
Combined treatment with ketoconazole and cyproterone acetate in a boy with McCune-Albright syndrome and peripheral precocious puberty. | Journal of endocrinological investigation 20080901 |
[A limited sampling strategy of phenotyping probe midazolam to predict inhibited activities of hepatic CYP3A in rats]. | Yao xue xue bao = Acta pharmaceutica Sinica 20080901 |
Overcoming undesirable CYP1A2 inhibition of pyridylnaphthalene-type aldosterone synthase inhibitors: influence of heteroaryl derivatization on potency and selectivity. | Journal of medicinal chemistry 20080828 |
Synthesis, biological evaluation, and molecular modeling of abiraterone analogues: novel CYP17 inhibitors for the treatment of prostate cancer. | Journal of medicinal chemistry 20080828 |
Synthesis, biological evaluation, and molecular modeling studies of methylene imidazole substituted biaryls as inhibitors of human 17alpha-hydroxylase-17,20-lyase (CYP17)--part II: Core rigidification and influence of substituents at the methylene bridge. | Bioorganic & medicinal chemistry 20080815 |
In situ dissolution testing using potentiometric sensors. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20080807 |
Cushing's disease in dogs: cabergoline treatment. | Research in veterinary science 20080801 |
Effects of ketoconazole and quinidine on pharmacokinetics of pactimibe and its plasma metabolite, R-125528, in humans. | Drug metabolism and disposition: the biological fate of chemicals 20080801 |
Pharmacokinetics of darunavir/ritonavir and ketoconazole following co-administration in HIV-healthy volunteers. | British journal of clinical pharmacology 20080801 |
Adverse effects of ketoconazole in dogs--a retrospective study. | Veterinary dermatology 20080801 |
Dysgonic strain of Microsporum canis pseudomycetoma in a Domestic Long-hair cat. | Australian veterinary journal 20080801 |
What's your assessment? Pityrosporum folliculitis. | Dermatology nursing 20080801 |
[Effect of ketoconazole on the activity of CYP4503A4 and CYP450 1A2 of hepatic microsomes in healthy adults]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20080801 |
Microsome biocolloids for rapid drug metabolism and inhibition assessment by LC-MS. | Drug metabolism letters 20080801 |
A statistical methodology for drug-drug interaction surveillance. | Statistics in medicine 20080720 |
Chemosensitization prevents tolerance of Aspergillus fumigatus to antimycotic drugs. | Biochemical and biophysical research communications 20080718 |
New trypanocidal hybrid compounds from the association of hydrazone moieties and benzofuroxan heterocycle. | Bioorganic & medicinal chemistry 20080715 |
Synthesis of novel ketoconazole derivatives as inhibitors of the human Pregnane X Receptor (PXR; NR1I2; also termed SXR, PAR). | Bioorganic & medicinal chemistry letters 20080715 |
Expression of microsomal lanosterol 14alpha-demethylase (CYP51) in an engineered soluble monomeric form. | Biochemical and biophysical research communications 20080711 |
1-[(3-Aryloxy-3-aryl)propyl]-1H-imidazoles, new imidazoles with potent activity against Candida albicans and dermatophytes. Synthesis, structure-activity relationship, and molecular modeling studies. | Journal of medicinal chemistry 20080710 |
A phase I study of docetaxel with ketoconazole modulation in patients with advanced cancers. | Cancer chemotherapy and pharmacology 20080701 |
Synthesis and antimicrobial activities of 7-O-modified genistein derivatives. | European journal of medicinal chemistry 20080701 |
Long-term treatment of familial male-limited precocious puberty (testotoxicosis) with cyproterone acetate or ketoconazole. | Clinical endocrinology 20080701 |
Paecilomyces lilacinus olecranon bursitis in an immunocompromised host: case report and review. | Diagnostic microbiology and infectious disease 20080701 |
Prediction of pharmacokinetic drug-drug interactions using human hepatocyte suspension in plasma and cytochrome P450 phenotypic data. II. In vitro-in vivo correlation with ketoconazole. | Drug metabolism and disposition: the biological fate of chemicals 20080701 |
Perturbation of gene expression and steroidogenesis with in vitro exposure of fathead minnow ovaries to ketoconazole. | Marine environmental research 20080701 |
Potent in vitro antifungal activities of naturally occurring acetylenic acids. | Antimicrobial agents and chemotherapy 20080701 |
Evaluation and treatment of oral candidiasis in HIV/AIDS patients in Enugu, Nigeria. | Oral and maxillofacial surgery 20080701 |
Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a range of phenyl alkyl imidazole-based compounds as potent inhibitors of the enzyme complex 17alpha-hydroxylase/17,20-lyase (P450(17alpha)). | The Journal of steroid biochemistry and molecular biology 20080701 |
Validation and application of Caco-2 assays for the in vitro evaluation of development candidate drugs as substrates or inhibitors of P-glycoprotein to support regulatory submissions. | Xenobiotica; the fate of foreign compounds in biological systems 20080701 |
[Ketoconazole and clindamycin efficacy vs oral clindamycin in premature membranes rupture prevention]. | Ginecologia y obstetricia de Mexico 20080701 |
Biotypes, genotypes and ketoconazole susceptibility of Candida albicans isolates from a group of Thai AIDS patients. | The new microbiologica 20080701 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). | Journal of medicinal chemistry 20080612 |
Differential effects of ketoconazole on exposure to temsirolimus following intravenous infusion of temsirolimus. | British journal of cancer 20080603 |
Malassezia folliculitis in China. | Mycopathologia 20080601 |
In vitro antifungal susceptibility and molecular characterization of clinical isolates of Fusarium verticillioides (F. moniliforme) and Fusarium thapsinum. | Antimicrobial agents and chemotherapy 20080601 |
Biweekly doxorubicin/ketoconazole as second-line treatment in docetaxel-resistant, hormone-refractory prostate cancer. | Urology 20080601 |
Cutaneous hyalohyphomycosis caused by a Chrysosporium species related to Nannizziopsis vriesii in two green iguanas (Iguana iguana). | Medical mycology 20080601 |
Synthesis and SAR studies of biaryloxy-substituted triazoles as antifungal agents. | Bioorganic & medicinal chemistry letters 20080601 |
Safety profile and metabolic effects of 14 days of treatment with DIO-902: results of a phase IIa multicenter, randomized, double-blind, placebo-controlled, parallel-group trial in patients with type 2 diabetes mellitus. | Clinical therapeutics 20080601 |
Application of micellar electrokinetic capillary chromatography for evaluation of inhibitory effects on cytochrome P450 reaction. | Journal of chromatography. A 20080502 |
Synthesis and antimicrobial activity of novel sulfone-linked bis heterocycles. | European journal of medicinal chemistry 20080501 |
An examination of the effect of intestinal first pass extraction on intestinal lymphatic transport of saquinavir in the rat. | Pharmaceutical research 20080501 |
A stereospecific high-performance liquid chromatographic assay for the determination of ketoconazole enantiomers in rat plasma. | Biomedical chromatography : BMC 20080501 |
Contribution of the N-glucuronidation pathway to the overall in vitro metabolic clearance of midazolam in humans. | Drug metabolism and disposition: the biological fate of chemicals 20080501 |
Application of CYP3A4 in vitro data to predict clinical drug-drug interactions; predictions of compounds as objects of interaction. | British journal of clinical pharmacology 20080501 |
In vitro inhibition of CYP3A4 metabolism and P-glycoprotein-mediated transport by trade herbal products. | Basic & clinical pharmacology & toxicology 20080501 |
Oral ketoconazole for prevention of postoperative penile erection: a placebo controlled, randomized, double-blind trial. | The Journal of urology 20080501 |
Identification of the human cytochrome P450 enzymes involved in the in vitro biotransformation of lynestrenol and norethindrone. | The Journal of steroid biochemistry and molecular biology 20080501 |
Chiral separations in sub- and supercritical fluid chromatography. | Journal of separation science 20080501 |
Identification of human cytochrome P450 enzymes involved in the metabolism of IN-1130, a novel activin receptor-like kinase-5 (ALK5) inhibitor. | Xenobiotica; the fate of foreign compounds in biological systems 20080501 |
Effects of ketoconazole on the pharmacokinetics and pharmacodynamics of morphine in healthy Greyhounds. | American journal of veterinary research 20080501 |
The effect of ketoconazole on the pharmacokinetics and pharmacodynamics of ixabepilone: a first in class epothilone B analogue in late-phase clinical development. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080501 |
Selected endocrine disrupting compounds (vinclozolin, flutamide, ketoconazole and dicofol): effects on survival, occurrence of males, growth, molting and reproduction of Daphnia magna. | Environmental science and pollution research international 20080501 |
Ketoconazole: a review of a workhorse antifungal molecule with a focus on new foam and gel formulations. | Drugs of today (Barcelona, Spain : 1998) 20080501 |
Significance of isolation and drug susceptibility testing of non-Candida albicans species causing oropharyngeal candidiasis in HIV patients. | The Southeast Asian journal of tropical medicine and public health 20080501 |
[Effect of polyoxyl ether analogous surfactants on the activity of cytochromes P450 3A in rats in vivo]. | Yao xue xue bao = Acta pharmaceutica Sinica 20080501 |
Design, synthesis, and biological evaluation of (hydroxyphenyl)naphthalene and -quinoline derivatives: potent and selective nonsteroidal inhibitors of 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD1) for the treatment of estrogen-dependent diseases. | Journal of medicinal chemistry 20080410 |
New selective inhibitors of steroid 11beta-hydroxylation in the adrenal cortex. Synthesis and structure-activity relationship of potent etomidate analogues. | Journal of medicinal chemistry 20080410 |
Spectroscopic and kinetic studies on the interaction of ketoconazole and povidone drugs with DDQ. | Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20080401 |
Ketoconazole-induced testicular damage in rats reduced by Gentiana extract. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20080401 |
[Management of hypercortisolism]. | La Revue de medecine interne 20080401 |
Unexpected emergence of acute hepatic injury in patients treated repeatedly with ketoconazole. | Journal of clinical gastroenterology 20080401 |
Effects of CYP3A4 inhibitors on the pharmacokinetics of maraviroc in healthy volunteers. | British journal of clinical pharmacology 20080401 |
'Anti-cortisolic' treatment of warts. | Journal of the European Academy of Dermatology and Venereology : JEADV 20080401 |
Combinatorial anti-Trichophyton effects of Ligusticum chuanxiong essential oil components with antibiotics. | Archives of pharmacal research 20080401 |
Phaeohyphomycosis caused by Ulocladium species in a cat. | The Veterinary record 20080329 |
Predominant role of 25OHD in the negative regulation of PTH expression: clinical relevance for hypovitaminosis D. | Life sciences 20080326 |
Synthesis, crystal structure and antimicrobial activity of deoxybenzoin derivatives from genistein. | European journal of medicinal chemistry 20080301 |
Inhibition of luteinizing hormone secretion by testosterone in men requires aromatization for its pituitary but not its hypothalamic effects: evidence from the tandem study of normal and gonadotropin-releasing hormone-deficient men. | The Journal of clinical endocrinology and metabolism 20080301 |
Mixed inhibition of P450 3A4 as a chemoprotective mechanism against aflatoxin B1-induced cytotoxicity with cis-terpenones. | Chemical research in toxicology 20080301 |
A novel ketoconazole bioadhesive effervescent tablet for vaginal delivery: design, in vitro and 'in vivo' evaluation. | International journal of pharmaceutics 20080227 |
Synthesis, biological evaluation and molecular modelling studies of methyleneimidazole substituted biaryls as inhibitors of human 17alpha-hydroxylase-17,20-lyase (CYP17). Part I: Heterocyclic modifications of the core structure. | Bioorganic & medicinal chemistry 20080215 |
Ethnoveterinary study for antidermatophytic activity of Piper betle, Alpinia galanga and Allium ascalonicum extracts in vitro. | Research in veterinary science 20080201 |
Pharmacological evaluation of C-3 modified Betulinic acid derivatives with potent anticancer activity. | Investigational new drugs 20080201 |
Antifungal canthin-6-one series accumulate in lipid droplets and affect fatty acid metabolism in Saccharomyces cerevisiae. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080201 |
Coexistence of hERG current block and disruption of protein trafficking in ketoconazole-induced long QT syndrome. | British journal of pharmacology 20080201 |
Ketoconazole and the modulation of multidrug resistance-mediated transport in Caco-2 and MDCKII-MDR1 drug transport models. | Xenobiotica; the fate of foreign compounds in biological systems 20080201 |
Ketoconazole, an antifungal imidazole, increases the sensitivity of rainbow trout to 17alpha-ethynylestradiol exposure. | Aquatic toxicology (Amsterdam, Netherlands) 20080131 |
Antifungal and cytotoxic activities of some N-substituted aniline derivatives bearing a hetaryl fragment. | Bioorganic & medicinal chemistry 20080115 |
[Prophylactic antifungal treatment in critically ill patients. A survey of a Cochrane review]. | Ugeskrift for laeger 20080107 |
New triazole and triazolothiadiazine derivatives as possible antimicrobial agents. | European journal of medicinal chemistry 20080101 |
Ritonavir 100 mg does not cause QTc prolongation in healthy subjects: a possible role as CYP3A inhibitor in thorough QTc studies. | Clinical pharmacology and therapeutics 20080101 |
Biochemical and functional evidence for the control of pain mechanisms by dehydroepiandrosterone endogenously synthesized in the spinal cord. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20080101 |
Prediction of onset of crystallization from experimental relaxation times. II. Comparison between predicted and experimental onset times. | Journal of pharmaceutical sciences 20080101 |
Pharmacokinetic interaction of ketoconazole and itraconazole with ciprofloxacin. | Biopharmaceutics & drug disposition 20080101 |
Spectrofluorimetric study and detection of ketoconazole in the presence of beta-cyclodextrin. | Journal of fluorescence 20080101 |
N-Phenyl and N-phenylalkyl-maleimides acting against Candida spp.: time-to-kill, stability, interaction with maleamic acids. | Bioorganic & medicinal chemistry 20080101 |
Novel cholesterol biosynthesis inhibitors targeting human lanosterol 14alpha-demethylase (CYP51). | Bioorganic & medicinal chemistry 20080101 |
The effects of CYP3A4 inhibition on erlotinib pharmacokinetics: computer-based simulation (SimCYP) predicts in vivo metabolic inhibition. | European journal of clinical pharmacology 20080101 |
Synthesis, biological evaluation and molecular modelling studies of novel ACD- and ABD-ring steroidomimetics as inhibitors of CYP17. | Bioorganic & medicinal chemistry letters 20080101 |
Activity of caspofungin and voriconazole against clinical isolates of Candida and other medically important yeasts by the CLSI M-44A disk diffusion method with Neo-Sensitabs tablets. | Chemotherapy 20080101 |
Ketoconazole revisited: a preoperative or postoperative treatment in Cushing's disease. | European journal of endocrinology 20080101 |
[Medical treatment for Cushing's syndrome]. | Nihon rinsho. Japanese journal of clinical medicine 20080101 |
[Ectopic Cushing's syndrome caused by a functioning pancreatic neuroendocrine tumour in a patient with von Hippel-Lindau disease]. | Revista espanola de medicina nuclear 20080101 |
Novel concepts in androgen receptor blockade. | Cancer journal (Sudbury, Mass.) 20080101 |
[Itraconazole treatment in the suspension of pathological fungal colonization of the airway in patients with pulmonary tuberculosis]. | Problemy tuberkuleza i boleznei legkikh 20080101 |
Dermatophyte susceptibilities to antifungal azole agents tested in vitro by broth macro and microdilution methods. | Revista do Instituto de Medicina Tropical de Sao Paulo 20080101 |
The effectiveness of retinoic acid treatment in bladder cancer: impact on recurrence, survival and TGFalpha and VEGF as end-point biomarkers. | Cancer biology & therapy 20080101 |
Prevention of bladder cancer recurrence by retinoic acid-ketoconazole: a promising strategy? | Cancer biology & therapy 20080101 |
Effect of coadministered ketoconazole, a strong cytochrome P450 3A4 enzyme inhibitor, on the pharmacokinetics of ciclesonide and its active metabolite desisobutyryl-ciclesonide. | Clinical pharmacokinetics 20080101 |
The metabolism of amiodarone by various CYP isoenzymes of human and rat, and the inhibitory influence of ketoconazole. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20080101 |
CYP2D6 is primarily responsible for the metabolism of clomiphene. | Drug metabolism and pharmacokinetics 20080101 |
[Susceptibility to antifungal agents among Cryptococcus neoformans varieties isolated from patients at a university hospital]. | Revista da Sociedade Brasileira de Medicina Tropical 20080101 |
Reduction of fluconazole susceptibility of Candida albicans in APECED patients due to long-term use of ketoconazole and miconazole. | Scandinavian journal of infectious diseases 20080101 |
[Mycetoma]. | Annales de dermatologie et de venereologie 20080101 |
Protothecosis as a cause of chronic diarrhoea in a dog. | Polish journal of veterinary sciences 20080101 |
A novel approach to the prediction of drug-drug interactions in humans based on the serum incubation method. | Drug metabolism and pharmacokinetics 20080101 |
A Bayesian meta-analysis on published sample mean and variance pharmacokinetic data with application to drug-drug interaction prediction. | Journal of biopharmaceutical statistics 20080101 |
Diffuse cutaneous leishmaniasis: co-infection with human immunodeficiency virus (HIV). | Indian journal of dermatology, venereology and leprology 20080101 |
Tinea nigra by Hortaea werneckii, a report of 22 cases from Mexico. | Studies in mycology 20080101 |
[Modern approach to treatment of trophic ulcers of legs with perifocal varicose eczema, associated with mycotic infection]. | Khirurgiia 20080101 |
Evaluation of the relationship between androgenetic alopecia and demodex infestation. | Indian journal of dermatology 20080101 |
[Resistance to azolic compounds in clinical Trichophyton spp. strains]. | Revista iberoamericana de micologia 20071231 |
Composition, enantiomeric distribution, and antimicrobial activity of Tanacetum argenteum subsp. flabellifolium essential oil. | Journal of pharmaceutical and biomedical analysis 20071221 |
Induction of the NAD(P)H:quinone oxidoreductase 1 by ketoconazole and itraconazole: a mechanism of cancer chemoprotection. | Cancer letters 20071208 |
Interactions of azole antifungal agents with the human breast cancer resistance protein (BCRP). | Journal of pharmaceutical sciences 20071201 |
Identification of human liver cytochrome P450 enzymes involved in biotransformation of vicriviroc, a CCR5 receptor antagonist. | Drug metabolism and disposition: the biological fate of chemicals 20071201 |
Cyclic conversion of the novel Src kinase inhibitor [7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine (TG100435) and Its N-oxide metabolite by flavin-containing monoxygenases and cytochrome P450 reductase. | Drug metabolism and disposition: the biological fate of chemicals 20071201 |
Effect of hydration on the permeation of ketoconazole through human nail plate in vitro. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20071201 |
Phase II study of ketoconazole plus granulocyte-macrophage colony-stimulating factor for prostate cancer: effect of extent of disease on outcome. | The Journal of urology 20071201 |
Cytochrome P3A4 inhibitors and other constituents of Fibraurea tinctoria. | Journal of natural products 20071201 |
Bioactive polychlorinated bibenzyls from the liverwort Riccardia polyclada. | Journal of natural products 20071201 |
Pharmacokinetic interaction between ketoconazole and praziquantel in healthy volunteers. | Journal of clinical pharmacy and therapeutics 20071201 |
Nodular pulmonary histoplasmosis in Cushing's disease: a case report and literature review. | Tennessee medicine : journal of the Tennessee Medical Association 20071201 |
Quantitative correlations among CYP3A sensitive substrates and inhibitors: literature analysis. | Current drug metabolism 20071201 |
In vivo anti-Chagas vinylthio-, vinylsulfinyl-, and vinylsulfonylbenzofuroxan derivatives. | Journal of medicinal chemistry 20071129 |
Induction of drought stress tolerance by ketoconazole in Catharanthus roseus is mediated by enhanced antioxidant potentials and secondary metabolite accumulation. | Colloids and surfaces. B, Biointerfaces 20071115 |
Rational prescription of drugs within similar therapeutic or structural class for gastrointestinal disease treatment: drug metabolism and its related interactions. | World journal of gastroenterology 20071114 |
Adaptive therapy for androgen-independent prostate cancer: a randomized selection trial of four regimens. | Journal of the National Cancer Institute 20071107 |
Pharmacokinetic modulation of oral etoposide by ketoconazole in patients with advanced cancer. | Cancer chemotherapy and pharmacology 20071101 |
The cytochrome p450 inhibitor ketoconazole potentiates 5-hydroxytryptamine-induced contraction in rat aorta. | The Journal of pharmacology and experimental therapeutics 20071101 |
Use of isolated hepatocyte preparations for cytochrome P450 inhibition studies: comparison with microsomes for Ki determination. | Drug metabolism and disposition: the biological fate of chemicals 20071101 |
Synthesis and antifungal activities of novel 2-aminotetralin derivatives. | Journal of medicinal chemistry 20071101 |
Cytotoxic doses of ketoconazole affect expression of a subset of hepatic genes. | Journal of toxicology and environmental health. Part A 20071101 |
[Malassezia folliculitis: characteristics and therapeutic response in 26 patients]. | Annales de dermatologie et de venereologie 20071101 |
Formulation compatibility of myristyl nicotinate with drugs used to treat dermatological conditions involving an impaired skin barrier. | Drug development and industrial pharmacy 20071101 |
Pharmacological management of Cushing's syndrome: an update. | Arquivos brasileiros de endocrinologia e metabologia 20071101 |
33-Year-old man with cough, fever, and weight loss. | Mayo Clinic proceedings 20071001 |
Metabolism of tacrolimus (FK506) and recent topics in clinical pharmacokinetics. | Drug metabolism and pharmacokinetics 20071001 |
A novel foam formulation of ketoconazole 2% for the treatment of seborrheic dermatitis on multiple body regions. | Journal of drugs in dermatology : JDD 20071001 |
Efficacy of low-dose ketoconazole in hormone refractory prostate cancer patients at the National Cancer Centre and The Cancer Institute, Singapore. | Annals of the Academy of Medicine, Singapore 20071001 |
The role of ketoconazole in seborrheic dermatitis. | Cutis 20071001 |
Effect of one month ketoconazole treatment on GH, cortisol and ACTH release after ghrelin, GHRP-6 and GHRH administration in patients with Cushing's disease. | Arquivos brasileiros de endocrinologia e metabologia 20071001 |
[Metabolic products and pathway of neferine in rat liver]. | Yao xue xue bao = Acta pharmaceutica Sinica 20071001 |
Drug-drug interaction prediction: a Bayesian meta-analysis approach. | Statistics in medicine 20070910 |
Influence of ketoconazole on the fecal and urinary disposition of docetaxel. | Cancer chemotherapy and pharmacology 20070901 |
Diagnosis and treatment of ocular coccidioidomycosis in a female captive chimpanzee (Pan troglodytes): a case study. | Annals of the New York Academy of Sciences 20070901 |
Synthesis of novel triazole derivatives as inhibitors of cytochrome P450 14alpha-demethylase (CYP51). | European journal of medicinal chemistry 20070901 |
Azole therapy of clinical and experimental coccidioidomycosis. | Annals of the New York Academy of Sciences 20070901 |
Ciclosporin use in multi-drug therapy for meningoencephalomyelitis of unknown aetiology in dogs. | The Journal of small animal practice 20070901 |
Effects of endocrine disrupting chemicals on expression of phospholipid hydroperoxide glutathione peroxidase mRNA in rat testes. | Journal of veterinary science 20070901 |
Restoration of hormonal action and muscle protein. | Critical care medicine 20070901 |
Effective treatment for dermatophytoses of the foot: effect on restoration of depressed cell-mediated immunity. | Journal of the European Academy of Dermatology and Venereology : JEADV 20070901 |
Candida interface keratitis after deep anterior lamellar keratoplasty: clinical, microbiologic, histopathologic, and confocal microscopic reports. | Cornea 20070901 |
Ketoconazole in the treatment of chronic idiopathic central serous chorioretinopathy. | Retina (Philadelphia, Pa.) 20070901 |
Development of an in vivo rat screen model to predict pharmacokinetic interactions of CYP3A4 substrates. | Xenobiotica; the fate of foreign compounds in biological systems 20070901 |
Raman, FT-IR, NMR spectroscopic data and antimicrobial activity of bis[micro2-(benzimidazol-2-yl)-2-ethanethiolato-N,S,S-chloro-palladium(II)] dimer, [(micro2-CH2CH2NHNCC6H4)PdCl]2.C2H5OH complex. | European journal of medicinal chemistry 20070801 |
Antiepileptic drugs affect neuronal androgen signaling via a cytochrome P450-dependent pathway. | The Journal of pharmacology and experimental therapeutics 20070801 |
Transcription of key genes regulating gonadal steroidogenesis in control and ketoconazole- or vinclozolin-exposed fathead minnows. | Toxicological sciences : an official journal of the Society of Toxicology 20070801 |
Combination of surgical avulsion and topical therapy for single nail onychomycosis: a randomized controlled trial. | The British journal of dermatology 20070801 |
Activity of ketoconazole against Mycobacterium tuberculosis in vitro and in the mouse model. | Journal of medical microbiology 20070801 |
Tinea capitis: no incision nor excision. | Journal of pediatric surgery 20070801 |
Ketoconazole is inferior to ritonavir as an alternative booster for saquinavir in a once daily regimen in Thai HIV-1 infected patients. | AIDS (London, England) 20070731 |
The prokinetic cinitapride has no clinically relevant pharmacokinetic interaction and effect on QT during coadministration with ketoconazole. | Drug metabolism and disposition: the biological fate of chemicals 20070701 |
Eumycetoma presenting as a cerebellopontine angle mass lesion. | Clinical neurology and neurosurgery 20070701 |
In vitro susceptibilities of 217 clinical isolates of zygomycetes to conventional and new antifungal agents. | Antimicrobial agents and chemotherapy 20070701 |
Cytochrome P450-dependent metabolism of vitamin E isoforms is a critical determinant of their tissue concentrations in rats. | Lipids 20070701 |
Identification and in vitro antifungal susceptibility testing of 200 clinical isolates of Candida spp. responsible for fingernail infections. | Mycopathologia 20070701 |
Comparison between fluconazole and ketoconazole effectivity in the treatment of pityriasis versicolor. | Mycoses 20070701 |
Oral paracoccidioidomycosis: a case without lung manifestations. | The journal of contemporary dental practice 20070701 |
Melanin biosynthesis in Madurella mycetomatis and its effect on susceptibility to itraconazole and ketoconazole. | Microbes and infection 20070701 |
Preparation, characterization, and scale-up of ketoconazole with enhanced dissolution and bioavailability. | Drug development and industrial pharmacy 20070701 |
Tailored hormonal therapy in secretory adrenocortical cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20070701 |
[Enzyme kinetics of schizandrin metabolism and sex differences in rat liver microsomes]. | Yao xue xue bao = Acta pharmaceutica Sinica 20070701 |
Optimisation of hydrocortisone production by Curvularia lunata. | Applied biochemistry and biotechnology 20070701 |
Comparison of fast liquid chromatography/tandem mass spectrometric methods for simultaneous determination of cladribine and clofarabine in mouse plasma. | Journal of pharmaceutical and biomedical analysis 20070628 |
Discovery of novel indazole-linked triazoles as antifungal agents. | Bioorganic & medicinal chemistry letters 20070615 |
Possible inhibitory mechanism of Curcuma drugs on CYP3A4 in 1alpha,25 dihydroxyvitamin D3 treated Caco-2 cells. | International journal of pharmaceutics 20070607 |
Hepatitis and rhabdomyolysis in a patient with hormone refractory prostate cancer on ketoconazole and concurrent lovastatin therapy. | Investigational new drugs 20070601 |
Pharmacological prevention of the deleterious effects of cardiopulmonary bypass. | Asian cardiovascular & thoracic annals 20070601 |
A new ketoconazole topical gel formulation in seborrhoeic dermatitis: an updated review of the mechanism. | Expert opinion on pharmacotherapy 20070601 |
Ketoconazole in the fathead minnow (Pimephales promelas): reproductive toxicity and biological compensation. | Environmental toxicology and chemistry 20070601 |
Life-threatening Pneumocystis jiroveci pneumonia following treatment of severe Cushing's syndrome. | The Netherlands journal of medicine 20070601 |
Non-interventional management of obstructive acute renal-failure in hormone-naïve prostate cancer. | The Canadian journal of urology 20070601 |
Electrochemical reduction of sterol-14alpha-demethylase from Mycobacterium tuberculosis (CYP51b1). | Biochemistry. Biokhimiia 20070601 |
Ketoconazole gel 2% in the treatment of moderate to severe seborrheic dermatitis. | Cutis 20070601 |
[Mediastinal lymph nodes during the course of a metastatic prostate cancer]. | Actas urologicas espanolas 20070601 |
Schistosoma haematobium and urinary tract pathogens co-infections in a rural community of Edo State, Nigeria. | The Journal of communicable diseases 20070601 |
A lesson for everyone in drug-drug interactions. | International journal of cardiology 20070516 |
MgMfs1, a major facilitator superfamily transporter from the fungal wheat pathogen Mycosphaerella graminicola, is a strong protectant against natural toxic compounds and fungicides. | Fungal genetics and biology : FG & B 20070501 |
Induction of cytochrome P450 1A1 by ketoconazole and itraconazole but not fluconazole in murine and human hepatoma cell lines. | Toxicological sciences : an official journal of the Society of Toxicology 20070501 |
Sequential metabolism is responsible for diltiazem-induced time-dependent loss of CYP3A. | Drug metabolism and disposition: the biological fate of chemicals 20070501 |
Antifungal susceptibility testing of Trichophyton rubrum by E-test. | Archives of dermatological research 20070501 |
Effect of efavirenz on the pharmacokinetics of ketoconazole in HIV-infected patients. | European journal of clinical pharmacology 20070501 |
Cytochrome P450 3A inhibition by ketoconazole affects prasugrel and clopidogrel pharmacokinetics and pharmacodynamics differently. | Clinical pharmacology and therapeutics 20070501 |
Estimation of intragastric solubility of drugs: in what medium? | Pharmaceutical research 20070501 |
Electrochemical properties of cytochroms P450 using nanostructured electrodes: direct electron transfer and electro catalysis. | Journal of inorganic biochemistry 20070501 |
Lecythophora hoffmannii isolated from a case of canine osteomyelitis in Japan. | Medical mycology 20070501 |
Flutrimazole shampoo 1% versus ketoconazole shampoo 2% in the treatment of pityriasis versicolor. A randomised double-blind comparative trial. | Mycoses 20070501 |
Plasma pharmacokinetics and CYP3A12-dependent metabolism of c-kit inhibitor imatinib in dogs. | Xenobiotica; the fate of foreign compounds in biological systems 20070501 |
Interventions for treating oral candidiasis for patients with cancer receiving treatment. | The Cochrane database of systematic reviews 20070418 |
Activated pregnenolone X-receptor is a target for ketoconazole and its analogs. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070415 |
Antifungal treatment in sarcoidosis--a pilot intervention trial. | Respiratory medicine 20070401 |
Characterization of hot-melt extruded drug delivery systems for onychomycosis. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070401 |
Synthesis and antimicrobial activities of Schiff bases derived from 5-chloro-salicylaldehyde. | European journal of medicinal chemistry 20070401 |
Luteinizing hormone-induced caspase activation in rat preovulatory follicles is coupled to mitochondrial steroidogenesis. | Endocrinology 20070401 |
Deacetylclivorine: a gender-selective metabolite of clivorine formed in female Sprague-Dawley rat liver microsomes. | Drug metabolism and disposition: the biological fate of chemicals 20070401 |
Second generation of 5-ethenylbenzofuroxan derivatives as inhibitors of Trypanosoma cruzi growth: synthesis, biological evaluation, and structure-activity relationships. | Bioorganic & medicinal chemistry 20070401 |
Synthesis of DL-standishinal and its related compounds for the studies on structure-activity relationship of inhibitory activity against aromatase. | Bioorganic & medicinal chemistry 20070401 |
In vitro activity of an ear rinse containing tromethamine, EDTA, benzyl alcohol and 0.1% ketoconazole on Malassezia organisms from dogs with otitis externa. | Veterinary dermatology 20070401 |
Adrenal androgen levels as predictors of outcome in prostate cancer patients treated with ketoconazole plus antiandrogen withdrawal: results from a cancer and leukemia group B study. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070401 |
Pharmacokinetic modelling of pentoxifylline and lisofylline after oral and intravenous administration in mice. | The Journal of pharmacy and pharmacology 20070401 |
[Lithium gluconate 8% in the treatment of seborrheic dermatitis]. | Annales de dermatologie et de venereologie 20070401 |
Inhibitory or scavenging action of ketoconazole and ciclopiroxolamine against reactive oxygen species released by primed inflammatory cells. | The British journal of dermatology 20070401 |
Effect of ion suppression on judgment of enzyme inhibition and avoidance of error by utilizing a stable isotope-labeled probe substrate: example of CYP3A4 inhibition with [13C4,15N] labeled midazolam as a substrate. | Drug metabolism and pharmacokinetics 20070401 |
[Cushing syndrome]. | Revue de l'infirmiere 20070401 |
[Effectiveness of the treatment plan for androgenetic alopecia]. | Georgian medical news 20070401 |
Eumycetoma pedis due to Exophiala jeanselmei. | Indian journal of medical microbiology 20070401 |
The development of a cocktail CYP2B6, CYP2C8, and CYP3A5 inhibition assay and a preliminary assessment of utility in a drug discovery setting. | Drug metabolism and disposition: the biological fate of chemicals 20070301 |
Effect of oral ketoconazole on intestinal first-pass effect of midazolam and fexofenadine in cynomolgus monkeys. | Drug metabolism and disposition: the biological fate of chemicals 20070301 |
Three-dimensional quantitative structure-activity relationship analysis of human CYP51 inhibitors. | Drug metabolism and disposition: the biological fate of chemicals 20070301 |
Antifungal activities of azole agents against the Malassezia species. | International journal of antimicrobial agents 20070301 |
Development of quantitative real-time PCR assays for fathead minnow (Pimephales promelas) gonadotropin beta subunit mRNAs to support endocrine disruptor research. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20070301 |
Potential cancer chemopreventive in vitro activities of monomeric xanthone derivatives from the marine algicolous fungus Monodictys putredinis. | Journal of natural products 20070301 |
Potentiating effects of nonactive/active vitamin D analogues and ketoconazole in parathyroid cells. | Clinical endocrinology 20070301 |
Metronidazole 0.75% gel vs. ketoconazole 2% cream in the treatment of facial seborrheic dermatitis: a randomized, double-blind study. | Journal of the European Academy of Dermatology and Venereology : JEADV 20070301 |
Clinical inquiries. What's the best treatment for cradle cap? | The Journal of family practice 20070301 |
Antiplasmodial interactions between artemisinin and triclosan or ketoconazole combinations against blood stages of Plasmodium falciparum in vitro. | The American journal of tropical medicine and hygiene 20070301 |
Report of an imported cutaneous disseminated case of paracoccidioidomycosis. | Revista iberoamericana de micologia 20070301 |
Hyperadrenocorticism: treating dogs. | Compendium (Yardley, PA) 20070301 |
CP-154,526, a CRF type-1 receptor antagonist, attenuates the cue-and methamphetamine-induced reinstatement of extinguished methamphetamine-seeking behavior in rats. | Psychopharmacology 20070201 |
Evidence of Oatp and Mdr1 in cryopreserved rat hepatocytes. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20070201 |
Synthesis, characterization and antimicrobial activity of Fe(II), Zn(II), Cd(II) and Hg(II) complexes with 2,6-bis(benzimidazol-2-yl) pyridine ligand. | European journal of medicinal chemistry 20070201 |
Inhibition of CYP3A4 and CYP3A5 catalyzed metabolism of alprazolam and quinine by ketoconazole as racemate and four different enantiomers. | European journal of clinical pharmacology 20070201 |
Transporter-mediated drug interactions: clinical implications and in vitro assessment. | Expert opinion on drug metabolism & toxicology 20070201 |
[A text-book case of tropical facial elephantiasis]. | Revue de stomatologie et de chirurgie maxillo-faciale 20070201 |
Concentrations of mycophenolic acid and glucuronide metabolites under concomitant therapy with cyclosporine or tacrolimus. | Therapeutic drug monitoring 20070201 |
[Oral isolates of Saccharomyces in patients with oral fungal infection and their susceptibility to antifungal drugs]. | Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20070201 |
[Acanthamoeba keratitis: about the first two Tunisian cases]. | Bulletin de la Societe de pathologie exotique (1990) 20070201 |
[Cutaneous sporotricosis in a Malagasy patient]. | Medecine tropicale : revue du Corps de sante colonial 20070201 |
Determination of antifungal activity of polyenzyme preparation Candidaseb using in vitro methods. | Hindustan antibiotics bulletin 20070201 |
Inhibition of drug metabolism by blocking the activation of nuclear receptors by ketoconazole. | Oncogene 20070111 |
Effects of three cytochrome P450 inhibitors, ketoconazole, fluconazole, and paroxetine, on the pharmacokinetics of lasofoxifene. | British journal of clinical pharmacology 20070101 |
Reversal of androgenetic alopecia by topical ketoconzole: relevance of anti-androgenic activity. | Journal of dermatological science 20070101 |
A novel model for the prediction of drug-drug interactions in humans based on in vitro cytochrome p450 phenotypic data. | Drug metabolism and disposition: the biological fate of chemicals 20070101 |
Synthesis and antifungal activity of (Z)-5-arylidenerhodanines. | Bioorganic & medicinal chemistry 20070101 |
Design of endoperoxides with anti-Candida activity. | Bioorganic & medicinal chemistry 20070101 |
Molecular evidence and functional expression of multidrug resistance associated protein (MRP) in rabbit corneal epithelial cells. | Experimental eye research 20070101 |
Antimicrobial effectiveness of ketoconazole against metronidazole-resistant Helicobacter pylori isolates from Iranian dyspeptic patients. | The Journal of antimicrobial chemotherapy 20070101 |
The stereoselective metabolism of halofantrine to desbutylhalofantrine in the rat: evidence of tissue-specific enantioselectivity in microsomal metabolism. | Chirality 20070101 |
CYP3A4 mediated in vitro metabolism of vinflunine in human liver microsomes. | Acta pharmacologica Sinica 20070101 |
1H NMR monitoring of the canine metabolic profile after oral administration of xenobiotics using multivariate statistics. | Molecular pharmaceutics 20070101 |
Value of colposcopy in the diagnosis of candidiasis in patients with vulvodynia. | The Journal of reproductive medicine 20070101 |
Simultaneous determination of docetaxel and ketoconazole in rat plasma by liquid chromatography/electrospray ionization tandem mass spectrometry. | Rapid communications in mass spectrometry : RCM 20070101 |
Comparison of different perrmeation enhancers on topical ketoconazole formulations. | Arzneimittel-Forschung 20070101 |
Human intestinal P-glycoprotein activity estimated by the model substrate digoxin. | Scandinavian journal of clinical and laboratory investigation 20070101 |
Ketoconazole therapy: an efficacious alternative to achieve eucortisolism in patients with Cushing's syndrome. | Medicina 20070101 |
Antiviral and antimicrobial profiles of selected isoquinoline alkaloids from Fumaria and Corydalis species. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101 |
Abdominal wall mycetoma presented as obstructed incisional hernia of cesarean section in eastern Sudan. | Infectious diseases in obstetrics and gynecology 20070101 |
Significant prostate-specific antigen (PSA) response to low-dose ketoconazole in a patient with non-metastatic androgen-independent prostate cancer (AIPC) and a review of the literature. | American journal of therapeutics 20070101 |
Pharmacokinetics of cinacalcet hydrochloride when administered with ketoconazole. | Clinical pharmacokinetics 20070101 |
Clinical efficacies of shampoos containing ciclopirox olamine (1.5%) and ketoconazole (2.0%) in the treatment of seborrhoeic dermatitis. | The Journal of dermatological treatment 20070101 |
Simultaneous ectopic adrenocorticotropic hormone syndrome and adrenal metastasis of a medullary thyroid carcinoma causing paraneoplastic Cushing's syndrome. | International seminars in surgical oncology : ISSO 20070101 |
Extina foam (2%). | Skinmed 20070101 |
Multiple oral dosing of ketoconazole increases dog exposure to ivermectin. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20070101 |
Ketoconazole-evoked [Ca2+]i rises and non-Ca2+-triggered cell death in rabbit corneal epithelial cells (SIRC). | Journal of receptor and signal transduction research 20070101 |
[Quo vadis, hypophysis? Some news and prospects]. | Vnitrni lekarstvi 20070101 |
Localized cutaneous leishmaniasis in South India: successful treatment with ketoconazole. | Indian journal of dermatology, venereology and leprology 20070101 |
CYP3A4 and pregnane X receptor humanized mice. | Journal of biochemical and molecular toxicology 20070101 |
[The 50th Anniversary Educational Symposium of the Japanese Society for Medical Mycology: Dermatomycoses caused by Malassezia]. | Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20070101 |
Effect of hypercortisolism control on high blood pressure in Cushing's syndrome. | Medicina 20070101 |
Identification of CYP3A4 as the primary cytochrome P450 responsible for the metabolism of tandospirone by human liver microsomes. | European journal of drug metabolism and pharmacokinetics 20070101 |
In vitro release--in vivo microbiological and toxicological studies on ketoconazole lipid granules. | Pharmaceutical development and technology 20070101 |
Identification of CYP3A4 as the primary cytochrome P450 responsible for the metabolism of tandospirone by human liver microsomes. | European journal of drug metabolism and pharmacokinetics 20070101 |
In vitro antifungal activity of 2-(4-substituted phenyl)-3(2H)-isothiazolones. | Folia microbiologica 20070101 |
Pregnenolone and dexamethasone, modulators of cytochrome P450-3A, not increase but reduce urinary alpha-CEHC excretion in rats. | BioFactors (Oxford, England) 20070101 |
Seborrhoeic dermatitis. | BMJ clinical evidence 20070101 |
Treatment algorithm in hormone-resistant prostate cancer: Practical guidelines. | Indian journal of urology : IJU : journal of the Urological Society of India 20070101 |
Repeated 28-day oral toxicity study of ketoconazole in rats based on the draft protocol for the 'Enhanced OECD Test Guideline No. 407' to detect endocrine effects. | Archives of toxicology 20061201 |
The role of P-glycoprotein in the bioactivation of raloxifene. | Drug metabolism and disposition: the biological fate of chemicals 20061201 |
Drug-metabolizing enzyme inhibition by ketoconazole does not reduce interindividual variability of CYP3A activity as measured by oral midazolam. | Drug metabolism and disposition: the biological fate of chemicals 20061201 |
Antifungal susceptibilities of the species of the Pseudallescheria boydii complex. | Antimicrobial agents and chemotherapy 20061201 |
Antifolates as antimycotics? Connection between the folic acid cycle and the ergosterol biosynthesis pathway in Candida albicans. | International journal of antimicrobial agents 20061201 |
Cytochrome P450-dependent metabolism of midazolam in hepatic microsomes from chickens, turkeys, pheasant and bobwhite quail. | Journal of veterinary pharmacology and therapeutics 20061201 |
White piedra in children. | Journal of the American Academy of Dermatology 20061201 |
In vitro antifungal efficacy of ciclopirox olamine alone and associated with zinc pyrithione compared to ketoconazole against Malassezia globosa and Malassezia restricta reference strains. | Mycopathologia 20061201 |
Mechanisms of venoocclusive disease resulting from the combination of cyclophosphamide and roxithromycin. | Therapeutic drug monitoring 20061201 |
Preoperative immunosuppressive therapy and surgery as a treatment for anal furunculosis. | Veterinary surgery : VS 20061201 |
Bioactive oligostilbenoids from the stem bark of Hopea exalata. | Journal of natural products 20061201 |
Evaluation of the effects of hydrophilic organic solvents on CYP3A-mediated drug-drug interaction in vitro. | Human & experimental toxicology 20061201 |
[Study on metabolism of tetramethylpyrazine in system of rat liver microsomes]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20061201 |
[Canine lymphadenitis caused by Cryptococcus neoformans. First case in Chile]. | Revista iberoamericana de micologia 20061201 |
Common pharmacophores for uncharged human ether-a-go-go-related gene (hERG) blockers. | Journal of medicinal chemistry 20061116 |
Human adrenocarcinoma (H295R) cells for rapid in vitro determination of effects on steroidogenesis: hormone production. | Toxicology and applied pharmacology 20061115 |
The H295R system for evaluation of endocrine-disrupting effects. | Ecotoxicology and environmental safety 20061101 |
Effectiveness and tolerability of a standardized extract from Ageratina pichinchensis on patients with tinea pedis: an explorative pilot study controlled with ketoconazole. | Planta medica 20061101 |
In vitro methods for antifungal susceptibility testing of Trichophyton spp. | Mycological research 20061101 |
Otomycosis: clinical features and treatment implications. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20061101 |
OPC-67683, a nitro-dihydro-imidazooxazole derivative with promising action against tuberculosis in vitro and in mice. | PLoS medicine 20061101 |
Inhibition of the enzymatic activity of heme oxygenases by azole-based antifungal drugs. | The Journal of pharmacology and experimental therapeutics 20061001 |
Characterization of the rhesus monkey CYP3A64 enzyme: species comparisons of CYP3A substrate specificity and kinetics using baculovirus-expressed recombinant enzymes. | Drug metabolism and disposition: the biological fate of chemicals 20061001 |
Metabolism of endosulfan-alpha by human liver microsomes and its utility as a simultaneous in vitro probe for CYP2B6 and CYP3A4. | Drug metabolism and disposition: the biological fate of chemicals 20061001 |
Influence of tartaric acid on the bioadhesion and mechanical properties of hot-melt extruded hydroxypropyl cellulose films for the human nail. | Drug development and industrial pharmacy 20061001 |
Decision support tool to individualize cyclosporine dose in stable, long-term heart transplant recipients receiving metabolic inhibitors: overcoming limitations of cyclosporine C2 monitoring. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20061001 |
In-vitro susceptibility testing by agar dilution method to determine the minimum inhibitory concentrations of amphotericin B, fluconazole and ketoconazole against ocular fungal isolates. | Indian journal of medical microbiology 20061001 |
A fission yeast-based test system for the determination of IC50 values of anti-prostate tumor drugs acting on CYP21. | Journal of enzyme inhibition and medicinal chemistry 20061001 |
Evidence for cytochrome P450 3A expression and catalytic activity in rat blood lymphocytes. | Life sciences 20060927 |
Synthesis, biochemical evaluation and rationalisation of the inhibitory activity of a range of 4-substituted phenyl alkyl imidazole-based inhibitors of the enzyme complex 17alpha-hydroxylase/17,20-lyase (P450(17alpha)). | Bioorganic & medicinal chemistry letters 20060915 |
Retinoic acid as a novel medical therapy for Cushing's disease in dogs. | Endocrinology 20060901 |
Response to low-dose ketoconazole and subsequent dose escalation to high-dose ketoconazole in patients with androgen-independent prostate cancer. | Cancer 20060901 |
Disopyramide: although potentially life-threatening in the setting of long QT, could it be life-saving in short QT syndrome? | Journal of molecular and cellular cardiology 20060901 |
Metabolism and metabolic inhibition of gambogic acid in rat liver microsomes. | Acta pharmacologica Sinica 20060901 |
Metabolic activation of pradefovir by CYP3A4 and its potential as an inhibitor or inducer. | Antimicrobial agents and chemotherapy 20060901 |
RAT CYP3A and CYP2B1/2 were not associated with nevirapine-induced hepatotoxicity. | Methods and findings in experimental and clinical pharmacology 20060901 |
Intervention at the level of the neuroendocrine-immune axis and postoperative pneumonia rate in long-term alcoholics. | American journal of respiratory and critical care medicine 20060815 |
Suppressive effects of antimycotics on tumor necrosis factor-alpha-induced CCL27, CCL2, and CCL5 production in human keratinocytes. | Biochemical pharmacology 20060814 |
The use of a fluorescence-based oxygen uptake assay in the analysis of cytotoxicity. | Toxicology in vitro : an international journal published in association with BIBRA 20060801 |
Novel ketoconazole analogues based on the replacement of 2,4-dichlorophenyl group with 1,4-benzothiazine moiety: design, synthesis, and microbiological evaluation. | Bioorganic & medicinal chemistry 20060801 |
Inhibition of UDP-glucuronosyltransferase 2b7-catalyzed morphine glucuronidation by ketoconazole: dual mechanisms involving a novel noncompetitive mode. | Drug metabolism and disposition: the biological fate of chemicals 20060801 |
Activating mutations in the luteinizing hormone receptor gene: a human model of non-follicle-stimulating hormone-dependent inhibin production and germ cell maturation. | The Journal of clinical endocrinology and metabolism 20060801 |
Synthesis and biochemical evaluation of a range of potent benzyl imidazole-based compounds as potential inhibitors of the enzyme complex 17alpha-hydroxylase/17,20-lyase (P450(17alpha)). | Bioorganic & medicinal chemistry letters 20060801 |
Use of omeprazole sulfone in a single plasma sample as a probe for CYP3A4. | European journal of clinical pharmacology 20060801 |
Secondary hormonal manipulations in prostate cancer. | Hematology/oncology clinics of North America 20060801 |
Transporter-mediated intestinal absorption of fexofenadine in rats. | Drug metabolism and pharmacokinetics 20060801 |
Cushing's paraneoplastic syndrome as first manifestation of an adenocarcinoma of unknown origin. | Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico 20060801 |
Optimization and validation of a high-performance liquid chromatographic method with UV detection for the determination of ketoconazole in canine plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060724 |
Enhancement of DMNQ-induced hepatocyte toxicity by cytochrome P450 inhibition. | Toxicology and applied pharmacology 20060715 |
Clinical results of topical fluconazole for the treatment of filamentous fungal keratitis. | Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie 20060701 |
Stereoselective metabolism of endosulfan by human liver microsomes and human cytochrome P450 isoforms. | Drug metabolism and disposition: the biological fate of chemicals 20060701 |
Quinacrine is mainly metabolized to mono-desethyl quinacrine by CYP3A4/5 and its brain accumulation is limited by P-glycoprotein. | Drug metabolism and disposition: the biological fate of chemicals 20060701 |
Expression, purification, and characterization of mouse CYP2d22. | Drug metabolism and disposition: the biological fate of chemicals 20060701 |
Ketoconazole and miconazole are antagonists of the human glucocorticoid receptor: consequences on the expression and function of the constitutive androstane receptor and the pregnane X receptor. | Molecular pharmacology 20060701 |
Stochastic prediction of CYP3A-mediated inhibition of midazolam clearance by ketoconazole. | Drug metabolism and disposition: the biological fate of chemicals 20060701 |
Influence of high-dose ketoconazole on the pharmacokinetics of docetaxel. | Cancer biology & therapy 20060701 |
In vitro susceptibilities of Malaysian clinical isolates of Cryptococcus neoformans var. grubii and Cryptococcus gattii to five antifungal drugs. | Mycoses 20060701 |
Predictive power of an in vitro system to assess drug interactions of an antimuscarinic medication: a comparison of in vitro and in vivo drug-drug interaction studies of trospium chloride with digoxin. | Journal of clinical pharmacology 20060701 |
Pharmacokinetic effect of ketoconazole on solifenacin in healthy volunteers. | Basic & clinical pharmacology & toxicology 20060701 |
Phytochemistry and antifungal properties of the newly discovered tree Pleodendron costaricense. | Journal of natural products 20060701 |
Chronic mucocutaneous candidiasis associated with malignant thymoma and systemic lupus erythematosus with hypergammaglobulinemia: a case report and literature review. | Cutis 20060701 |
Interaction between ketoconazole and domperidone and the risk of QT prolongation--important safety information. | South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20060701 |
Pharmacokinetic interaction between ketoconazole and SPP301 in healthy volunteers. | International journal of clinical pharmacology and therapeutics 20060701 |
Biotransformation of fluticasone: in vitro characterization. | Drug metabolism and disposition: the biological fate of chemicals 20060601 |
Comparison of mouse and rat cytochrome P450-mediated metabolism in liver and intestine. | Drug metabolism and disposition: the biological fate of chemicals 20060601 |
Phase II study of mitoxantrone and ketoconazole for hormone-refractory prostate cancer. | Cancer 20060601 |
In vitro antifungal activities of Allium cepa, Allium sativum and ketoconazole against some pathogenic yeasts and dermatophytes. | Fitoterapia 20060601 |
Man versus machine: is there an optimal method for QT measurements in thorough QT studies? | Journal of clinical pharmacology 20060601 |
Cytoskeleton reassembly in cardiomyocytes infected by Trypanosoma cruzi is triggered by treatment with ergosterol biosynthesis inhibitors. | International journal of antimicrobial agents 20060601 |
Canine intestinal contents vs. simulated media for the assessment of solubility of two weak bases in the human small intestinal contents. | Pharmaceutical research 20060601 |
Antifungal effects of the volatile oils from Allium plants against Trichophyton species and synergism of the oils with ketoconazole. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20060601 |
Ketoconazole as a secondary hormonal intervention in advanced prostate cancer. | Clinical journal of oncology nursing 20060601 |
Polymorphic behaviour of Compritol888 ATO as bulk lipid and as SLN and NLC. | Journal of microencapsulation 20060601 |
Fungal toenail infections. | Clinical evidence 20060601 |
Surface plasmon resonance analysis of antifungal azoles binding to CYP3A4 with kinetic resolution of multiple binding orientations. | Biochemistry 20060523 |
Identification and quantitation of cis-ketoconazole impurity by capillary zone electrophoresis-mass spectrometry. | Journal of chromatography. A 20060505 |
alpha(2)-Adrenergic receptors activate MAPK and Akt through a pathway involving arachidonic acid metabolism by cytochrome P450-dependent epoxygenase, matrix metalloproteinase activation and subtype-specific transactivation of EGFR. | Cellular signalling 20060501 |
Lack of effect of ketoconazole-mediated CYP3A inhibition on sorafenib clinical pharmacokinetics. | Cancer chemotherapy and pharmacology 20060501 |
Metabolism and effect of para-toluene-sulfonamide on rat liver microsomal cytochrome P450 from in vivo and in vitro studies. | Acta pharmacologica Sinica 20060501 |
The use of SLN and NLC as topical particulate carriers for imidazole antifungal agents. | Die Pharmazie 20060501 |
[Skin infection with Fusarium in an immunocompetent patient]. | Actas dermo-sifiliograficas 20060501 |
[Three cases of cutaneous blastomycosis]. | Medecine et maladies infectieuses 20060501 |
Structure-based optimization of azole antifungal agents by CoMFA, CoMSIA, and molecular docking. | Journal of medicinal chemistry 20060420 |
Drugs for treating paracoccidioidomycosis. | The Cochrane database of systematic reviews 20060419 |
Synthesis and evaluation of heteroaryl-substituted dihydronaphthalenes and indenes: potent and selective inhibitors of aldosterone synthase (CYP11B2) for the treatment of congestive heart failure and myocardial fibrosis. | Journal of medicinal chemistry 20060406 |
Inhibition of the HERG K+ channel by the antifungal drug ketoconazole depends on channel gating and involves the S6 residue F656. | FEBS letters 20060403 |
Development, validation and utility of an in vitro technique for assessment of potential clinical drug-drug interactions involving P-glycoprotein. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060401 |
In vitro and in vivo inhibitory effect of stiripentol on clobazam metabolism. | Drug metabolism and disposition: the biological fate of chemicals 20060401 |
Interactions of two major metabolites of prasugrel, a thienopyridine antiplatelet agent, with the cytochromes P450. | Drug metabolism and disposition: the biological fate of chemicals 20060401 |
Identification of human liver cytochrome P450 enzymes responsible for the metabolism of lonafarnib (Sarasar). | Drug metabolism and disposition: the biological fate of chemicals 20060401 |
Antifungal agents for preventing fungal infections in non-neutropenic critically ill and surgical patients: systematic review and meta-analysis of randomized clinical trials. | The Journal of antimicrobial chemotherapy 20060401 |
Formation of 4'-carboxyl acid metabolite of imrecoxib by rat liver microsomes. | Acta pharmacologica Sinica 20060401 |
Long term control of hypercortisolism with fluconazole: case report and in vitro studies. | European journal of endocrinology 20060401 |
In vitro efficacy of a buffered chelating solution as an antimicrobial potentiator for antifungal drugs against fungal pathogens obtained from horses with mycotic keratitis. | American journal of veterinary research 20060401 |
Ketoconazole renders poor CYP3A phenotype status with midazolam as probe drug. | Therapeutic drug monitoring 20060401 |
Acanthamoeba keratitis in a 5-year-old boy without a history of contact lens usage. | Cornea 20060401 |
Aureobasidium pullulans keratitis. | Clinical & experimental ophthalmology 20060401 |
[The effect of propyl gallate on the activity of various antifungal drugs against filamentous fungi in vitro]. | [Zhonghua yan ke za zhi] Chinese journal of ophthalmology 20060401 |
The vitamin D prodrugs 1alpha(OH)D2, 1alpha(OH)D3 and BCI-210 suppress PTH secretion by bovine parathyroid cells. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20060301 |
Coxiella burnetii inhabits a cholesterol-rich vacuole and influences cellular cholesterol metabolism. | Cellular microbiology 20060301 |
Inhibition of Vitamin D3 metabolism enhances VDR signalling in androgen-independent prostate cancer cells. | The Journal of steroid biochemistry and molecular biology 20060301 |
[Penicilliosis in Laos]. | Presse medicale (Paris, France : 1983) 20060301 |
Novel endoperoxides: synthesis and activity against Candida species. | Bioorganic & medicinal chemistry letters 20060215 |
Partial structures of ketoconazole as modulators of the large conductance calcium-activated potassium channel (BK(Ca)). | Bioorganic & medicinal chemistry letters 20060215 |
Griseofulvin and ketoconazole solubilization by bile salts studied using fluorescence spectroscopy. | Colloids and surfaces. B, Biointerfaces 20060201 |
Clinical evolution of paracoccidioidomycosis in 38 children and teenagers. | Mycopathologia 20060201 |
Use of capecitabine after renal allograft transplantation in dog erythrocyte antigen-matched dogs. | Veterinary surgery : VS 20060201 |
CYP3A4 activity in four different animal species liver microsomes using 7-benzyloxyquinoline and HPLC/spectrofluorometric determination. | Journal of pharmaceutical and biomedical analysis 20060123 |
Development of a fluorescence-based assay for screening of modulators of human organic anion transporter 1B3 (OATP1B3). | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20060101 |
Dysmorphogenic effects of some fungicides derived from the imidazole on rat embryos cultured in vitro. | Reproductive toxicology (Elmsford, N.Y.) 20060101 |
Determination of the enzyme(s) involved in the metabolism of amiodarone in liver and intestine of rat: the contribution of cytochrome P450 3A isoforms. | Drug metabolism and disposition: the biological fate of chemicals 20060101 |
Intestinal and hepatic CYP3A4 catalyze hydroxylation of 1alpha,25-dihydroxyvitamin D(3): implications for drug-induced osteomalacia. | Molecular pharmacology 20060101 |
An unusual presentation of malassezia dermatosis. | Dermatology (Basel, Switzerland) 20060101 |
Hyperkeratotic head and neck Malassezia dermatosis. | Dermatology (Basel, Switzerland) 20060101 |
Impact of the cyclosporine-ketoconazole interaction in children with steroid-dependent idiopathic nephrotic syndrome. | European journal of clinical pharmacology 20060101 |
Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics. | British journal of clinical pharmacology 20060101 |
Bioavailability of two oral formulations of loratadine 20 mg with concomitant ketoconazole: an open-label, randomized, two-period crossover comparison in healthy Mexican adult volunteers. | Clinical therapeutics 20060101 |
Effect of drug utilization reviews on the quality of in-hospital prescribing: a quasi-experimental study. | BMC health services research 20060101 |
Recurrent vulvovaginal candidiasis. | Missouri medicine 20060101 |
Carney complex (CNC). | Orphanet journal of rare diseases 20060101 |
Malassezia and seborrheic dermatitis: etiology and treatment. | Journal of cosmetic science 20060101 |
Ketoconazole-tacrolimus coadministration in kidney transplant recipients: two-year results of a prospective randomized study. | American journal of nephrology 20060101 |
In vitro studies on quetiapine metabolism using the substrate depletion approach with focus on drug-drug interactions. | Drug metabolism and drug interactions 20060101 |
Efficacy and safety of a new once-daily topical ketoconazole 2% gel in the treatment of seborrheic dermatitis: a phase III trial. | Journal of drugs in dermatology : JDD 20060101 |
In vitro activity of R126638 and ketoconazole against Malassezia species. | Acta dermato-venereologica 20060101 |
Clinical features and diagnosis of 42 travellers with cutaneous leishmaniasis. | Travel medicine and infectious disease 20060101 |
[Effect of steroid biosynthesis modificators on the progesterone biotransformation by a recombinant yeasts expressing cytochrome P450c17]. | Biomeditsinskaia khimiia 20060101 |
Xolegel (ketoconazole, 2%). | Skinmed 20060101 |
[Drug-related problems in a patient with Cushing's disease]. | Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20060101 |
Mycetoma : a review. | American journal of clinical dermatology 20060101 |
Clinical efficacy of a new ciclopiroxolamine/zinc pyrithione shampoo in scalp seborrheic dermatitis treatment. | European journal of dermatology : EJD 20060101 |
Effect of ketoconazole and rifampicin on the pharmacokinetics of ranitidine in healthy human volunteers: a possible role of P-glycoprotein. | Drug metabolism and drug interactions 20060101 |
Effect of ketoconazole on the pharmacokinetics of ornidazole--a possible role of p-glycoprotein and CYP3A. | Drug metabolism and drug interactions 20060101 |
[Laboratory evolutive aspects of children under paracoccidioidomycosis treatment]. | Revista da Sociedade Brasileira de Medicina Tropical 20060101 |
Co-administration of ketoconazole and tacrolimus therapy: a transplanted rat model. | International urology and nephrology 20060101 |
[Relative bioavailability and bioequivalence of the antimycotics ketoconazole and fluconazole]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20060101 |
In vitro susceptibility of oral Candida to seven antifungal agents. | Oral microbiology and immunology 20051201 |
Significant differences in the disposition of cyclic prodrugs of opioid peptides in rats and guinea pigs following IV administration. | Journal of pharmaceutical sciences 20051201 |
Bioactive small molecules reveal antagonism between the integrated stress response and sterol-regulated gene expression. | Cell metabolism 20051201 |
Evaluation and treatment of Cushing's syndrome. | The American journal of medicine 20051201 |
A comparison of hair quality and cosmetic acceptance following the use of two anti-dandruff shampoos. | The journal of investigative dermatology. Symposium proceedings 20051201 |
Effects of beta-thujaplicin on anti-Malassezia pachydermatis remedy for canine otitis externa. | The Journal of veterinary medical science 20051201 |
Ketoconazole induced torsades de pointes without concomitant use of QT interval-prolonging drug. | Journal of cardiovascular electrophysiology 20051201 |
Fungal nail infections. | Clinical evidence 20051201 |
Candidiasis (vulvovaginal). | Clinical evidence 20051201 |
Novel tetralone-derived retinoic acid metabolism blocking agents: synthesis and in vitro evaluation with liver microsomal and MCF-7 CYP26A1 cell assays. | Journal of medicinal chemistry 20051117 |
Characterization of rat small intestinal and colon precision-cut slices as an in vitro system for drug metabolism and induction studies. | Drug metabolism and disposition: the biological fate of chemicals 20051101 |
Uncommon clinical presentations of cutaneous leishmaniasis in Sudan. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20051101 |
Upregulation of sterol C14-demethylase expression in Trypanosoma cruzi treated with sterol biosynthesis inhibitors. | Molecular and biochemical parasitology 20051101 |
Effect of azole antifungals ketoconazole and fluconazole on the pharmacokinetics of dexloxiglumide. | British journal of clinical pharmacology 20051101 |
The effect of calcium chelating or binding agents on Candida albicans. | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20051101 |
Clinical status of agents being developed for leishmaniasis. | Expert opinion on investigational drugs 20051101 |
Extraction, hemisynthesis, and synthesis of canthin-6-one analogues. Evaluation of their antifungal activities. | Journal of natural products 20051101 |
An overview of antifungal drugs and their use for treatment of deep and superficial mycoses in animals. | Clinical techniques in small animal practice 20051101 |
[Metabolic kinetics of MN9202 in Beagle dog liver microsomes]. | Yao xue xue bao = Acta pharmaceutica Sinica 20051101 |
Increase of the LC-MS/MS sensitivity and detection limits using on-line sample preparation with large volume plasma injection. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20051025 |
Characterization of human cytochrome P450 isoenzymes involved in the metabolism of vinorelbine. | Fundamental & clinical pharmacology 20051001 |
[Drug-drug interaction of antifungal drugs]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20051001 |
The effects of inhibiting cytochrome P450 3A, p-glycoprotein, and gastric acid secretion on the oral bioavailability of methadone in dogs. | Journal of veterinary pharmacology and therapeutics 20051001 |
Enantiomeric separation of ketoconazole and terconazole antifungals by electrokinetic chromatography: Rapid quantitative analysis of ketoconazole in pharmaceutical formulations. | Electrophoresis 20051001 |
The role of ketoconazole in the prevention of ovarian hyperstimulation syndrome in patients with polycystic ovary syndrome during assisted reproductive technology cycles. | Saudi medical journal 20051001 |
Effects of ketoconazole on glucuronidation by UDP-glucuronosyltransferase enzymes. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050915 |
[Determination of antidangdruff agent salicylic acid, zinc pyrithione, octopirox, climbazole and ketoconazole in shampoo by high performance liquid chromatography]. | Wei sheng yan jiu = Journal of hygiene research 20050901 |
Increased expression and hotspot mutations of the multidrug efflux transporter, CDR1 in azole-resistant Candida albicans isolates from vaginitis patients. | FEMS microbiology letters 20050815 |
Metabolism of the alpha,beta-unsaturated ketones, chalcone and trans-4-phenyl-3-buten-2-one, by rat liver microsomes and estrogenic activity of the metabolites. | Drug metabolism and disposition: the biological fate of chemicals 20050801 |
The advantages of the Ussing chamber in drug absorption studies. | Journal of biomolecular screening 20050801 |
2-O-(2-hydroxybutyl)-beta-cyclodextrin as a chiral selector for the capillary electrophoretic separation of chiral drugs. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20050801 |
DNA fingerprinting pattern and susceptibility to antifungal drugs in Cryptococcus neoformans variety grubii isolates from Barcelona city and rural environmental samples. | Mycopathologia 20050801 |
Identification of OATP1B3 as a high-affinity hepatocellular transporter of paclitaxel. | Cancer biology & therapy 20050801 |
Ketobemidone is a substrate for cytochrome P4502C9 and 3A4, but not for P-glycoprotein. | Xenobiotica; the fate of foreign compounds in biological systems 20050801 |
SLN and NLC for topical delivery of ketoconazole. | Journal of microencapsulation 20050801 |
[3H]linopirdine binding to rat brain membranes is not relevant for M-channel interaction. | European journal of pharmacology 20050725 |
Development and application of a new on-line SPE system combined with LC-MS/MS detection for high throughput direct analysis of pharmaceutical compounds in plasma. | Journal of chromatography. A 20050708 |
Effect of several compounds on biliary excretion of paclitaxel and its metabolites in guinea-pigs. | Anti-cancer drugs 20050701 |
Dimemorfan N-demethylation by mouse liver microsomal cytochrome P450 enzymes. | Life sciences 20050701 |
Alanine scanning of transmembrane helix 11 of Cdr1p ABC antifungal efflux pump of Candida albicans: identification of amino acid residues critical for drug efflux. | The Journal of antimicrobial chemotherapy 20050701 |
A novel foam vehicle for delivery of topical corticosteroids. | Journal of the American Academy of Dermatology 20050701 |
Rate-limiting biotransformation of triamterene is mediated by CYP1A2. | International journal of clinical pharmacology and therapeutics 20050701 |
Fusarium solani breast abscess. | Indian journal of medical microbiology 20050701 |
[In vitro activity of ketoconazole, itraconazole and terbinafine against Malassezia strains isolated from neonates]. | Mikrobiyoloji bulteni 20050701 |
Characterization of testosterone 11 beta-hydroxylation catalyzed by human liver microsomal cytochromes P450. | Drug metabolism and disposition: the biological fate of chemicals 20050601 |
Long-term outcome for men with androgen independent prostate cancer treated with ketoconazole and hydrocortisone. | The Journal of urology 20050601 |
Ketoconazole increases plasma concentrations of antimalarial mefloquine in healthy human volunteers. | Journal of clinical pharmacy and therapeutics 20050601 |
The effect of ketoconazole on the pharmacokinetics of a selective alpha 1A-adrenoceptor antagonist. | Journal of clinical pharmacology 20050601 |
Genome-wide expression profiling of the response to azole, polyene, echinocandin, and pyrimidine antifungal agents in Candida albicans. | Antimicrobial agents and chemotherapy 20050601 |
Comparison of the clinical efficacy of oral terbinafine and ketoconazole combined with cephalexin in the treatment of Malassezia dermatitis in dogs--a pilot study. | Veterinary dermatology 20050601 |
[Abdominal zygomycosis in a bitch due to Absidia corymbifera]. | Revista iberoamericana de micologia 20050601 |
Effect of 2-(4-aminophenylmethyl)-6-hydroxy-3, 4-dihydronaphthalen-1(2H)-one on all-trans and 13-cis-retinoic acid levels in plasma quantified by high perfomance liquid chromatography coupled to tandem mass spectrometry. | Journal of enzyme inhibition and medicinal chemistry 20050601 |
[Allergic fungal sinusitis and allergic broncho-pulmonary aspergillosis: a fortuitous association or a nosological rhino-bronchial entity?]. | Revue des maladies respiratoires 20050601 |
[Comparison of efficacy of combination of ketokonazol 400 mg + clindamycin 100 mg with ketokonazol 800 mg + clindamycin 100 mg in the treatment of vaginitis due to Candida and bacterial vaginosis]. | Ginecologia y obstetricia de Mexico 20050601 |
Lack of cataleptogenic potentiation with non-imidazole H3 receptor antagonists reveals potential drug-drug interactions between imidazole-based H3 receptor antagonists and antipsychotic drugs. | Brain research 20050531 |
Selective inhibition of dog hepatic CYP2B11 and CYP3A12. | The Journal of pharmacology and experimental therapeutics 20050501 |
Intestinal metabolism of PAH: in vitro demonstration and study of its impact on PAH transfer through the intestinal epithelium. | Environmental research 20050501 |
Anti-proliferative synergy of lysophospholipid analogues and ketoconazole against Trypanosoma cruzi (Kinetoplastida: Trypanosomatidae): cellular and ultrastructural analysis. | The Journal of antimicrobial chemotherapy 20050501 |
Blood concentrations of everolimus are markedly increased by ketoconazole. | Journal of clinical pharmacology 20050501 |
Comparison of in vitro activities of antifungal drugs and ethanolic extract of propolis against Trichophyton rubrum and T. mentagrophytes by using a microdilution assay. | Mycoses 20050501 |
Separation study of cadmium as CdI4(2-) through a bulk liquid membrane containing ketoconazole and oleic acid. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20050501 |
Effect of solubilizing and microemulsifying excipients in polyethylene glycol 6000 solid dispersion on enhanced dissolution and bioavailability of ketoconazole. | Archives of pharmacal research 20050501 |
Mefloquine resistance reversal action of ketoconazole - a cytochrome P450 inhibitor, against mefloquine-resistant malaria. | Parasitology 20050501 |
Slime production and proteinase activity of Candida species isolated from blood samples and the comparison of these activities with minimum inhibitory concentration values of antifungal agents. | Memorias do Instituto Oswaldo Cruz 20050501 |
Cloning and heterologous expression of the NADPH cytochrome P450 oxidoreductase genes from an industrial dicarboxylic acid-producing Candida tropicalis. | Yeast (Chichester, England) 20050430 |
Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model. | Journal of medicinal chemistry 20050421 |
Enhancement of nifedipine-induced gingival overgrowth by concomitant ketoconazole in rats. | Pharmacology 20050401 |
Xenobiotics and the glucocorticoid receptor: additive antagonistic effects on tyrosine aminotransferase activity in rat hepatoma cells. | Basic & clinical pharmacology & toxicology 20050401 |
Studies to investigate the pharmacokinetic interactions between ranolazine and ketoconazole, diltiazem, or simvastatin during combined administration in healthy subjects. | Journal of clinical pharmacology 20050401 |
Transient band-like keratopathy after treatment for seborrheic dermatitis. | Cornea 20050401 |
A study of the in vitro interaction between lidocaine and premedications using human liver microsomes. | Journal of clinical pharmacy and therapeutics 20050401 |
Topical application of ketoconazole stimulates hair growth in C3H/HeN mice. | The Journal of dermatology 20050401 |
Hepatotoxicity associated with cyclosporine monitoring using C2 recommendations in adults renal recipients receiving ketoconazole. | Transplantation proceedings 20050401 |
Assessment of the hepatic and intestinal first-pass metabolism of midazolam in a CYP3A drug-drug interaction model rats. | Xenobiotica; the fate of foreign compounds in biological systems 20050401 |
Oxidative stress mediates drug-induced hepatotoxicity in rats: a possible role of DNA fragmentation. | Toxicology 20050330 |
Synthesis and evaluation of imidazolylmethylenetetrahydronaphthalenes and imidazolylmethyleneindanes: potent inhibitors of aldosterone synthase. | Journal of medicinal chemistry 20050324 |
Microbiological assay of ketoconazole in shampoo. | International journal of pharmaceutics 20050323 |
Synthesis and evaluation of (pyridylmethylene)tetrahydronaphthalenes/-indanes and structurally modified derivatives: potent and selective inhibitors of aldosterone synthase. | Journal of medicinal chemistry 20050310 |
Metabolism of alfentanil by cytochrome p4503a (cyp3a) enzymes. | Drug metabolism and disposition: the biological fate of chemicals 20050301 |
Experimentally induced androgen depletion accentuates ethnicity-related contrasts in luteinizing hormone secretion in asian and caucasian men. | The Journal of clinical endocrinology and metabolism 20050301 |
Characterization of human cytochrome P450 enzymes involved in the in vitro metabolism of perospirone. | Biopharmaceutics & drug disposition 20050301 |
Refractory anaphylactic shock associated with ketoconazole treatment. | The Annals of pharmacotherapy 20050301 |
A randomized, phase II trial of ketoconazole plus alendronate versus ketoconazole alone in patients with androgen independent prostate cancer and bone metastases. | The Journal of urology 20050301 |
Population-based case-control study of oral ketoconazole treatment for birth outcomes. | Congenital anomalies 20050301 |
Pityriasis versicolor alba. | Journal of the European Academy of Dermatology and Venereology : JEADV 20050301 |
Co-administration of ketoconazole with H1-antagonists ebastine and loratadine in healthy subjects: pharmacokinetic and pharmacodynamic effects. | British journal of clinical pharmacology 20050301 |
Seborrheic dermatitis. The link between facial rash and neurologic disease. | Postgraduate medicine 20050301 |
Effect of ketoconazole on the pharmacokinetics and safety of telithromycin and clarithromycin in older subjects with renal impairment. | International journal of clinical pharmacology and therapeutics 20050301 |
Pharmacological management of paracoccidioidomycosis. | Expert opinion on pharmacotherapy 20050301 |
Molecular design of two sterol 14alpha-demethylase homology models and their interactions with the azole antifungals ketoconazole and bifonazole. | Journal of computer-aided molecular design 20050301 |
A simultaneous assessment of CYP3A4 metabolism and induction in the DPX-2 cell line. | The AAPS journal 20050301 |
CYP3A4 is a vitamin D-24- and 25-hydroxylase: analysis of structure function by site-directed mutagenesis. | The Journal of clinical endocrinology and metabolism 20050201 |
In vivo effects of cyclosporin A and ketoconazole on the pharmacokinetics of representative substrates for P-glycoprotein and cytochrome P450 (CYP) 3A in rats. | Biological & pharmaceutical bulletin 20050201 |
[Metabolism of bicyclol in rat and human liver microsomes in vitro]. | Yao xue xue bao = Acta pharmaceutica Sinica 20050201 |
Role of ketoconazole in renal transplant recipients. | Transplantation 20050127 |
Antifungal and insect antifeedant 2-phenylethanol esters from the liverwort Balantiopsis cancellata from Chile. | Journal of agricultural and food chemistry 20050126 |
Age and testosterone feedback jointly control the dose-dependent actions of gonadotropin-releasing hormone in healthy men. | The Journal of clinical endocrinology and metabolism 20050101 |
Adult height after ketoconazole treatment in patients with familial male-limited precocious puberty. | The Journal of clinical endocrinology and metabolism 20050101 |
A phase I study of estramustine, weekly docetaxel, and carboplatin chemotherapy in patients with hormone-refractory prostate cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050101 |
Potent CYP3A4 inhibitory constituents of Piper cubeba. | Journal of natural products 20050101 |
Corneofungimetry bioassay on Malassezia spp. under ketoconazole and desonide influences. | Skin pharmacology and physiology 20050101 |
Determination of the absolute configuration and solution conformation of the antifungal agents ketoconazole, itraconazole, and miconazole with vibrational circular dichroism. | Chirality 20050101 |
Co-administration of cyclosporine and ketoconazole in children with minimal change nephrotic syndrome. | Nephron. Clinical practice 20050101 |
[Entomophthoramycosis (zygomycosis) caused by Conidiobolus coronatus in Mato Grosso (Brazil): case report]. | Revista da Sociedade Brasileira de Medicina Tropical 20050101 |
Phaeohyphomycosis in Korea. | Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20050101 |
Clinical treatment of corneal infection due to Fonsecaea pedrosoi--case report. | Arquivos brasileiros de oftalmologia 20050101 |
Estimation of potency of HERG channel blockers: impact of voltage protocol and temperature. | Journal of pharmacological and toxicological methods 20050101 |
Antifungal susceptibilities of dermatophytic agents isolated from clinical specimens. | European journal of dermatology : EJD 20050101 |
Case report of subcutaneous entomophthoromycosis with retroperitoneal invasion. | Revista da Sociedade Brasileira de Medicina Tropical 20050101 |
Efficient short-term control of hypercortisolaemia by low-dose etomidate in severe paediatric Cushing's disease. | Hormone research 20050101 |
Trichophyton tonsurans associated tinea corporis infection with the development of Majocchi's granuloma in a renal transplant patient. | Journal of drugs in dermatology : JDD 20050101 |
Co-administration of ketoconazole and tacrolimus therapy: a transplanted rat model. | International urology and nephrology 20050101 |
An evaluation of high-doses ketoconazole with hydrocortisone substitution in hormone-refractory prostate cancer. | Acta chirurgica Iugoslavica 20050101 |
[Effect of tofisopam on CYP3A4 enzyme activity on human recombinant 3A4 supersome]. | Acta pharmaceutica Hungarica 20050101 |
[Successful treatment of a case of extense verrucous chromoblastomychosis with surgical exeresis associated with the use of ketoconazole]. | Revista cubana de medicina tropical 20050101 |
Novel retinoic acid metabolism blocking agents endowed with multiple biological activities are efficient growth inhibitors of human breast and prostate cancer cells in vitro and a human breast tumor xenograft in nude mice. | Journal of medicinal chemistry 20041230 |
Potent, selective and low-calcemic inhibitors of CYP24 hydroxylase: 24-sulfoximine analogues of the hormone 1alpha,25-dihydroxyvitamin D(3). | Journal of medicinal chemistry 20041230 |
In vitro metabolism of carbofuran by human, mouse, and rat cytochrome P450 and interactions with chlorpyrifos, testosterone, and estradiol. | Chemico-biological interactions 20041207 |
Identification and characterization of potent CYP3A4 inhibitors in Schisandra fruit extract. | Drug metabolism and disposition: the biological fate of chemicals 20041201 |
Influence of ketoconazole on azimilide pharmacokinetics in healthy subjects. | British journal of clinical pharmacology 20041201 |
Synergistic interaction between ketoconazole and several antidepressant drugs with allopregnanolone treatments in ovariectomized Wistar rats forced to swim. | Progress in neuro-psychopharmacology & biological psychiatry 20041201 |
In vitro antifungal activity of sertaconazole compared with nine other drugs against 250 clinical isolates of dermatophytes and Scopulariopsis brevicaulis. | Chemotherapy 20041201 |
Combination therapy of once-weekly fluconazole (100, 150, or 300 mg) with topical application of ketoconazole cream in the treatment of onychomycosis. | Japanese journal of infectious diseases 20041201 |
Clinicopathologic features of an unusual outbreak of cryptococcosis in dogs, cats, ferrets, and a bird: 38 cases (January to July 2003). | Journal of the American Veterinary Medical Association 20041201 |
Effect of various cytochrome P450 3A and P-glycoprotein modulators on the biliary clearance of bromosulphaphthalein in male wistar rats. | Die Pharmazie 20041201 |
Synthesis and antileishmanial activity of 3-imidazolylalkylindoles. Part I. | Journal of enzyme inhibition and medicinal chemistry 20041201 |
Gamma-tocotrienol metabolism and antiproliferative effect in prostate cancer cells. | Annals of the New York Academy of Sciences 20041201 |
Seborrhoeic dermatitis. | Clinical evidence 20041201 |
Synthesis and CYP24 inhibitory activity of 2-substituted-3,4-dihydro-2H-naphthalen-1-one (tetralone) derivatives. | Bioorganic & medicinal chemistry letters 20041115 |
Tumor apoptosis induced by ruthenium(II)-ketoconazole is enhanced in nonsusceptible carcinoma by monoclonal antibody to EGF receptor. | International journal of cancer 20041110 |
A phase I trial of pharmacokinetic modulation of carboxyamidotriazole (CAI) with ketoconazole in patients with advanced cancer. | Cancer chemotherapy and pharmacology 20041101 |
Effects of acute and chronic ketoconazole administration on hypothalamo--pituitary--adrenal axis activity and brain corticotropin-releasing hormone. | Psychoneuroendocrinology 20041101 |
(2S,3R)-2-aminododecan-3-ol, a new antifungal agent from the ascidian Clavelina oblonga. | Journal of natural products 20041101 |
Vulvovaginal candidiasis in children and adolescents with type 1 diabetes mellitus. | Journal of pediatric endocrinology & metabolism : JPEM 20041101 |
[Treatment for seborrheic dermatitis]. | Annales de dermatologie et de venereologie 20041101 |
Pharmacokinetic interaction between ketoconazole and imatinib mesylate (Glivec) in healthy subjects. | Cancer chemotherapy and pharmacology 20041001 |
Stress-restress evokes sustained iNOS activity and altered GABA levels and NMDA receptors in rat hippocampus. | Psychopharmacology 20041001 |
Effect of ketoconazole on the pharmacokinetics of rosiglitazone in healthy subjects. | British journal of clinical pharmacology 20041001 |
The systemic treatment of onychomycosis. | Clinics in podiatric medicine and surgery 20041001 |
Pathogenesis of allergic bronchopulmonary aspergillosis and an evidence-based review of azoles in treatment. | Respiratory medicine 20041001 |
Multiple oral dosing of ketoconazole influences pharmacokinetics of quinidine after intravenous and oral administration in beagle dogs. | Journal of veterinary pharmacology and therapeutics 20041001 |
Comparative evaluation of Sensititre YeastOne vs. the NCCLS M27A protocol and E-test for antifungal susceptibility testing of yeasts. | Mycoses 20041001 |
Anti-Candida effects of estragole in combination with ketoconazole or amphotericin B. | Phytotherapy research : PTR 20041001 |
Influence of human nail etching for the assessment of topical onychomycosis therapies. | International journal of pharmaceutics 20040910 |
Concomitant administration of cyclosporine and ketoconazole in idiopathic nephrotic syndrome. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040901 |
Co-administration of cyclosporine and ketoconazole in idiopathic childhood nephrosis. | Pediatric nephrology (Berlin, Germany) 20040901 |
CYP2B6, CYP3A4, and CYP2C19 are responsible for the in vitro N-demethylation of meperidine in human liver microsomes. | Drug metabolism and disposition: the biological fate of chemicals 20040901 |
Identification of an N-methyl-4-phenylpyridinium-like metabolite of the antidiarrheal agent loperamide in human liver microsomes: underlying reason(s) for the lack of neurotoxicity despite the bioactivation event. | Drug metabolism and disposition: the biological fate of chemicals 20040901 |
In vitro metabolism of MK-0767 [(+/-)-5-[(2,4-dioxothiazolidin-5-yl)methyl]-2-methoxy-N-[[(4-trifluoromethyl) phenyl]methyl]benzamide], a peroxisome proliferator-activated receptor alpha/gamma agonist. I. Role of cytochrome P450, methyltransferases, flavin monooxygenases, and esterases. | Drug metabolism and disposition: the biological fate of chemicals 20040901 |
Effect of cytochrome P450 inhibitors (diethyl dithiocarbamate, ketoconazole and grapefruit juice) on the pharmacokinetics of all-trans-retinoic acid. | Farmaco (Societa chimica italiana : 1989) 20040901 |
Comparative study of 2% ketoconazole cream and 1% hydrocortisone cream in the treatment of infantile seborrheic dermatitis. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20040901 |
Use of oral ketoconazole to prevent postoperative erections following penile surgery. | International journal of impotence research 20040801 |
Interaction of triazolam and ketoconazole in P-glycoprotein-deficient mice. | Drug metabolism and disposition: the biological fate of chemicals 20040801 |
Concurrent Fusarium chlamydosporum and Microsphaeropsis arundinis infections in a cat. | Journal of feline medicine and surgery 20040801 |
Ketoconazole, a cytochrome P450 3A4 inhibitor, markedly increases concentrations of levo-acetyl-alpha-methadol in opioid-naive individuals. | Clinical pharmacology and therapeutics 20040801 |
Paranasal sinus aspergillosis: its categorization to develop a treatment protocol. | Mycoses 20040801 |
Invasion of epithelial mammalian cells by Paracoccidioides brasiliensis leads to cytoskeletal rearrangement and apoptosis of the host cell. | Microbes and infection 20040801 |
Specific interactions of steroids, arylhydrocarbons and flavonoids with progesterone receptors from the cytosol of the fungus Rhizopus nigricans. | The Journal of steroid biochemistry and molecular biology 20040801 |
Imidazole analogues of fluoxetine, a novel class of anti-Candida agents. | Journal of medicinal chemistry 20040729 |
Computer-assisted design of selective imidazole inhibitors for cytochrome p450 enzymes. | Journal of medicinal chemistry 20040701 |
Bioequivalence evaluation of two brands of ketoconazole tablets (Onofin-K and Nizoral) in a healthy female Mexican population. | Biopharmaceutics & drug disposition 20040701 |
Sesquiterpenes and flavonol glycosides from Zingiber aromaticum and their CYP3A4 and CYP2D6 inhibitory activities. | Journal of natural products 20040701 |
Ketoconazole, an antifungal agent, protects against adiposity induced by a cafeteria diet. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20040701 |
Improved outcome of zygomycosis in patients with hematological diseases? | Leukemia & lymphoma 20040701 |
Prescribing practices for seborrheic dermatitis vary with the physician's specialty: implications for clinical practice. | The Journal of dermatological treatment 20040701 |
Antifungal chalcones and new caffeic acid esters from Zuccagnia punctata acting against soybean infecting fungi. | Journal of agricultural and food chemistry 20040602 |
Co-administration of ketoconazole to tacrolimus-treated kidney transplant recipients: a prospective randomized study. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040601 |
Oral administration of a low dose of midazolam (75 microg) as an in vivo probe for CYP3A activity. | European journal of clinical pharmacology 20040601 |
Susceptibility of sequential Fonsecaea pedrosoi isolates from chromoblastomycosis patients to antifungal agents. | Mycoses 20040601 |
Lipid raft polarization contributes to hyphal growth in Candida albicans. | Eukaryotic cell 20040601 |
Chromoblastomycosis caused by Rhinocladiella aquaspersa. | Medical mycology 20040601 |
Antifungal susceptibility of 50 Candida isolates from invasive mycoses in Chile. | Medical mycology 20040601 |
Human cytochrome P450: metabolism of testosterone by CYP3A4 and inhibition by ketoconazole. | Current protocols in toxicology 20040601 |
A prospective, randomized study of coadministration of ketoconazole and cyclosporine a in kidney transplant recipients: ten-year follow-up. | Transplantation 20040515 |
An evaluation of intermediate-dose ketoconazole in hormone refractory prostate cancer. | European urology 20040501 |
The use of a cyclosporin-ketoconazole combination: making renal transplantation affordable in developing countries. | European journal of clinical pharmacology 20040501 |
Effect of cytochrome P450 3A4 inhibition on the pharmacokinetics of docetaxel. | Clinical pharmacology and therapeutics 20040501 |
Comparison of capillary zone electrophoresis and high performance liquid chromatography methods for quantitative determination of ketoconazole in drug formulations. | Farmaco (Societa chimica italiana : 1989) 20040501 |
Pharmacologic management of pattern hair loss. | Facial plastic surgery clinics of North America 20040501 |
Efficacy of combined cyclosporine A and ketoconazole treatment of anal furunculosis. | The Journal of small animal practice 20040501 |
Multicentric lymphoma in a dog after cyclosporine therapy. | The Journal of small animal practice 20040501 |
Effects of the antifungal imidazole ketoconazole on CYP1A and CYP3A in rainbow trout and killifish. | Environmental toxicology and chemistry 20040501 |
Model for the drug-drug interaction responsible for CYP3A enzyme inhibition. I: evaluation of cynomolgus monkeys as surrogates for humans. | Xenobiotica; the fate of foreign compounds in biological systems 20040501 |
Model for the drug-drug interaction responsible for CYP3A enzyme inhibition. II: establishment and evaluation of dexamethasone-pretreated female rats. | Xenobiotica; the fate of foreign compounds in biological systems 20040501 |
Identification and relative contributions of human cytochrome P450 isoforms involved in the metabolism of glibenclamide and lansoprazole: evaluation of an approach based on the in vitro substrate disappearance rate. | Xenobiotica; the fate of foreign compounds in biological systems 20040501 |
Role of CYP3A enzymes in the biotransformation of triazolam in rat liver. | Xenobiotica; the fate of foreign compounds in biological systems 20040501 |
Cyclosporine and low-dose ketoconazole in renal transplant recipients: a single-center experience. | Transplantation 20040415 |
In vitro metabolism of fipronil by human and rat cytochrome P450 and its interactions with testosterone and diazepam. | Chemico-biological interactions 20040415 |
The use of the novel substrate-heme complex approach in the derivation of a representation of the active site of the enzyme complex 17alpha-hydroxylase and 17,20-lyase. | Biochemical and biophysical research communications 20040409 |
Comparison of prediction methods for in vivo clearance of (S,S)-3-[3-(methylsulfonyl)phenyl]-1-propylpiperidine hydrochloride, a dopamine D2 receptor antagonist, in humans. | Drug metabolism and disposition: the biological fate of chemicals 20040401 |
Quantitative contribution of CYP2D6 and CYP3A to oxycodone metabolism in human liver and intestinal microsomes. | Drug metabolism and disposition: the biological fate of chemicals 20040401 |
Prevalence of Candida dubliniensis among germ tube-positive yeasts recovered from the respiratory specimens in HIV-negative patients. | Mycoses 20040401 |
Prostate cancer metastasis to supraclavicular lymph node. | Clinical advances in hematology & oncology : H&O 20040401 |
Distinct groups of multidrug resistance modulating agents are distinguished by competition of P-glycoprotein-specific antibodies. | Biochemical and biophysical research communications 20040319 |
Antiandrogen withdrawal alone or in combination with ketoconazole in androgen-independent prostate cancer patients: a phase III trial (CALGB 9583). | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20040315 |
History of the development of azole derivatives. | Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20040301 |
[Ketoconazole in the prevention of acute delirium episodes]. | Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) 20040301 |
Solubilizing poorly soluble antimycotic agents by emulsification via a solvent-free process. | AAPS PharmSciTech 20040301 |
Chronic mucocutaneous candidiasis: a case report. | Journal of the Indian Society of Pedodontics and Preventive Dentistry 20040301 |
Role of multiple drug resistance protein 1 in neutral but not acidic glycosphingolipid biosynthesis. | The Journal of biological chemistry 20040227 |
Sirolimus and ketoconazole co-prescription in renal transplant recipients. | Transplantation 20040215 |
Synthesis and antifungal activities of phenylenedithioureas. | Bioorganic & medicinal chemistry letters 20040209 |
Enantioselectivity of inhibition of cytochrome P450 3A4 (CYP3A4) by ketoconazole: Testosterone and methadone as substrates. | Chirality 20040201 |
Comparative efficacy of topical therapy with a slow-release mucoadhesive buccal tablet containing miconazole nitrate versus systemic therapy with ketoconazole in HIV-positive patients with oropharyngeal candidiasis. | Journal of acquired immune deficiency syndromes (1999) 20040201 |
Development of an in vivo preclinical screen model to estimate absorption and first-pass hepatic extraction of xenobiotics. II. Use of ketoconazole to identify P-glycoprotein/CYP3A-limited bioavailability in the monkey. | Drug metabolism and disposition: the biological fate of chemicals 20040201 |
Efficacy of a new ketoconazole bioadhesive vaginal tablet on Candida albicans. | Farmaco (Societa chimica italiana : 1989) 20040201 |
[Modern antimycotics. What the treating physician needs to know]. | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20040201 |
Role of phenobarbital-inducible cytochrome P450s as a source of active oxygen species in DNA-oxidation. | Cancer letters 20040120 |
Synthesis of galactopyranosyl amino alcohols as a new class of antitubercular and antifungal agents. | Bioorganic & medicinal chemistry letters 20040119 |
Highly selective inhibition of human CYP3Aa in vitro by azamulin and evidence that inhibition is irreversible. | Drug metabolism and disposition: the biological fate of chemicals 20040101 |
Ketocazole as an adjunct to finasteride in the treatment of androgenetic alopecia in men. | Medical hypotheses 20040101 |
High-throughput screening for the assessment of time-dependent inhibitions of new drug candidates on recombinant CYP2D6 and CYP3A4 using a single concentration method. | Xenobiotica; the fate of foreign compounds in biological systems 20040101 |
Interventions for treating oral candidiasis for patients with cancer receiving treatment. | The Cochrane database of systematic reviews 20040101 |
Drug-drug interactions evaluated by a highly active reconstituted native human cytochrome P4503A4 and human NADPH-cytochrome P450 reductase system. | Arzneimittel-Forschung 20040101 |
The role of cytochrome-P450 inhibitors in the prevention of hepatotoxicity after paracetamol overdose in rats. | Human & experimental toxicology 20040101 |
Oral paracoccidioidomycosis or squamous cell carcinoma? | General dentistry 20040101 |
Antimycotics: why are they effective in the treatment of seborrheic dermatitis? | Dermatology (Basel, Switzerland) 20040101 |
Effect of concomitant administration of cyclosporine and ketoconazole in children with focal segmental glomerulosclerosis. | American journal of nephrology 20040101 |
In vitro fungitoxic activity of Larrea divaricata cav. extracts. | Letters in applied microbiology 20040101 |
Azoles for allergic bronchopulmonary aspergillosis associated with asthma. | The Cochrane database of systematic reviews 20040101 |
In vitro antifungal susceptibility of Candida spp. isolates from patients with chronic periodontitis and from control patients. | Brazilian oral research 20040101 |
In vitro susceptibility of Candida species isolated from cancer patients to some antifungal agents. | Drug metabolism and drug interactions 20040101 |
[Determination of biological activity of hydrogel preparations based on ketoconazole and clotrimazole]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20040101 |
Resistance reversal action of ketoconazole against mefloquine resistance of Plasmodium yoelii nigeriensis. | Experimental parasitology 20040101 |
Determination of pharmaceutical compounds in skin by imaging matrix-assisted laser desorption/ionisation mass spectrometry. | Rapid communications in mass spectrometry : RCM 20040101 |
Antifungal effects of herbal essential oils alone and in combination with ketoconazole against Trichophyton spp. | Journal of applied microbiology 20040101 |
Etest for assessing the susceptibility of filamentous fungi. | Acta microbiologica et immunologica Hungarica 20040101 |
Metastatic hepatic carcinoid associated with ectopic ACTH syndrome, resistant to octreotide and ketoconazole therapy. | Annals of Saudi medicine 20040101 |
In vitro activities of transition metal derivatives of ketoconazole and clotrimazole against a wild type strain of Saccharomyces cerevisiae in absence or presence of human neutrophils. | Arzneimittel-Forschung 20040101 |
Management of androgen-independent prostate cancer. | Cancer control : journal of the Moffitt Cancer Center 20040101 |
Spontaneous remission of Cushing's disease after disappearance of a microadenoma attached to the pituitary stalk. | Pituitary 20040101 |
[Prophylaxis of fungal infection in patients with hematologic neoplasms and severe neutropenia after high-dose chemotherapy]. | Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20040101 |
Cushing's disease and pregnancy. | Pituitary 20040101 |
[Current possibilities of using antimyocotic drugs in the treatment of various skin disorders]. | Wiadomosci parazytologiczne 20040101 |
The influence of ketoconazole on the activity of asparagine protease produced by Candida strains. | Research communications in molecular pathology and pharmacology 20040101 |
Microbial transformation of (-)-carvone. | Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101 |
Phase 3 randomized trial evaluating second-line hormonal therapy versus docetaxel-estramustine combination chemotherapy on progression-free survival in asymptomatic patients with a rising prostate-specific antigen level after hormonal therapy for prostate cancer: an Eastern Cooperative Oncology Group (E1899), Intergroup/Clinical Trials Support Unit study. | Urology 20031229 |
QT and RR intervals in conscious and anesthetized guinea pigs with highly varying RR intervals and given QTc-lengthening test articles. | Toxicological sciences : an official journal of the Society of Toxicology 20031201 |
Experimental evaluation of antifungal and antiseptic agents against Rhodotorula spp. | Mycoses 20031201 |
Trypanocidal constituents in plants 2.xanthones from the stem bark of Garcinia subelliptica. | Biological & pharmaceutical bulletin 20031201 |
Acute lung injury in 2003. | Acta pharmacologica Sinica 20031201 |
Successful treatment of dandruff with 1.5% ciclopirox olamine shampoo in Korea. | The Journal of dermatological treatment 20031201 |
Multiple mechanisms account for variation in base-line sensitivity to azole fungicides in field isolates of Mycosphaerella graminicola. | Pest management science 20031201 |
Liver cirrhosis developed after ketoconazole-induced acute hepatic injury. | Journal of gastroenterology and hepatology 20031201 |
Clofibrate, a peroxisome-proliferator, enhances reverse cholesterol transport through cytochrome P450 activation and oxysterol generation. | The Tohoku journal of experimental medicine 20031201 |
New triterpene glycosides from the stems of Anomospermum grandifolium. | Journal of natural products 20031201 |
Identification of the human cytochrome P450s responsible for the in vitro metabolism of a leukotriene B4 receptor antagonist, CP-195,543. | Xenobiotica; the fate of foreign compounds in biological systems 20031201 |
Emerging systemic pharmacologic approaches in acute respiratory distress syndrome. | Respiratory care clinics of North America 20031201 |
Cutaneous blastomycosis presenting as non-healing ulcer and responding to oral ketoconazole. | Dermatology online journal 20031201 |
Clinical strategies in the management of biochemical recurrence after radical prostatectomy. | Clinical prostate cancer 20031201 |
Candidiasis (vulvovaginal). | Clinical evidence 20031201 |
Stripping voltammetric and polarographic techniques for the determination of anti-fungal ketoconazole on the mercury electrode. | Journal of pharmaceutical and biomedical analysis 20031124 |
Threshold for antiproliferative and proapoptotic activity of ttaxol in HepG2 cells expressing human CYP3A4: effect of P-glycoprotein transporters. | Pharmacology 20031101 |
Pharmacokinetic and pharmacodynamic interactions of oral midazolam with ketoconazole, fluoxetine, fluvoxamine, and nefazodone. | Journal of clinical pharmacology 20031101 |
Docetaxel and ketoconazole in advanced hormone-refractory prostate carcinoma: a phase I and pharmacokinetic study. | Cancer 20031101 |
Fungal infection of sutureless self-sealing incision for cataract surgery. | Ophthalmology 20031101 |
A double-blind, randomized, placebo-controlled study to assess the efficacy of ketoconazole for reducing the risk of ovarian hyperstimulation syndrome. | Fertility and sterility 20031101 |
Ketoconazole alters cyclosporine pharmacokinetic profile and may predispose to acute rejection. | Transplantation proceedings 20031101 |
Unintentional rechallenge resulting in a causative relationship between ketoconazole and acute liver injury. | International journal of clinical practice 20031101 |
Identification and prediction of promiscuous aggregating inhibitors among known drugs. | Journal of medicinal chemistry 20031009 |
Ketoconazole-induced neurologic sequelae. | Veterinary and human toxicology 20031001 |
Ketoconazole and lopinavir/ritonavir coadministration: boosting beyond boosting. | AIDS research and human retroviruses 20031001 |
Antifungal pharmacotherapy for neonatal candidiasis. | Seminars in perinatology 20031001 |
Fungal dermatitis with olanzapine in schizophrenia. | Canadian journal of psychiatry. Revue canadienne de psychiatrie 20031001 |
Clotrimazole, ketoconazole, and clodinafop-propargyl inhibit the in vitro growth of Babesia bigemina and Babesia bovis (Phylum Apicomplexa). | Parasitology 20031001 |
Lem3p is essential for the uptake and potency of alkylphosphocholine drugs, edelfosine and miltefosine. | The Journal of biological chemistry 20030919 |
Genome-wide expression profiling of the response to polyene, pyrimidine, azole, and echinocandin antifungal agents in Saccharomyces cerevisiae. | The Journal of biological chemistry 20030912 |
Effect of ketoconazole on venlafaxine plasma concentrations in extensive and poor metabolisers of debrisoquine. | European journal of clinical pharmacology 20030901 |
The effect of ketoconazole and diltiazem on oestrogen metabolism in postmenopausal women after single dose oestradiol treatment. | British journal of clinical pharmacology 20030901 |
Application of compartmental modeling to an examination of in vitro intestinal permeability data: assessing the impact of tissue uptake, P-glycoprotein, and CYP3A. | Drug metabolism and disposition: the biological fate of chemicals 20030901 |
Metabolism and elimination of quinine in healthy volunteers. | European journal of clinical pharmacology 20030901 |
Antileishmanial activities of dihydrochalcones from piper elongatum and synthetic related compounds. Structural requirements for activity. | Bioorganic & medicinal chemistry 20030901 |
Long-term results of treatment in patients with ACTH-secreting pituitary macroadenomas. | European journal of endocrinology 20030901 |
Disseminated paracoccidioidomycosis: correlation between clinical and in vitro resistance to ketoconazole and trimethoprim sulphamethoxazole. | Mycoses 20030901 |
A red rash on the face. | The Journal of family practice 20030901 |
Gastric function in the elderly: effects on absorption of ketoconazole. | Journal of clinical pharmacology 20030901 |
Limited utility of cyclosporine C2 monitoring in heart transplant recipients receiving ketoconazole. | Transplantation proceedings 20030901 |
Effect of antifungal drugs on pathogenic Naegleria spp isolated from natural water sources. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20030901 |
Fluorine substitution can block CYP3A4 metabolism-dependent inhibition: identification of (S)-N-[1-(4-fluoro-3- morpholin-4-ylphenyl)ethyl]-3- (4-fluorophenyl)acrylamide as an orally bioavailable KCNQ2 opener devoid of CYP3A4 metabolism-dependent inhibition. | Journal of medicinal chemistry 20030828 |
[Therapeutic safety of antimycotics in the treatment of systemic fungal infections]. | Orvosi hetilap 20030824 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods. | Bioorganic & medicinal chemistry letters 20030818 |
Substituent effect on the reductive N-dearylation of 3-(indol-1-yl)-1,2-benzisoxazoles by rat liver microsomes. | Drug metabolism and disposition: the biological fate of chemicals 20030801 |
Quantitative determination of some pharmaceutical piperazine derivatives through complexation with iron(III) chloride. | Farmaco (Societa chimica italiana : 1989) 20030801 |
Hepatotoxicity and toxicokinetics of ketoconazole in rabbits. | Acta pharmacologica Sinica 20030801 |
In vitro susceptibility testing of ciclopirox, terbinafine, ketoconazole and itraconazole against dermatophytes and nondermatophytes, and in vitro evaluation of combination antifungal activity. | The British journal of dermatology 20030801 |
Activities of therapeutic agents against Naegleria fowleri in vitro and in a mouse model of primary amebic meningoencephalitis. | The Journal of parasitology 20030801 |
Selectivities of human cytochrome P450 inhibitors toward rat P450 isoforms: study with cDNA-expressed systems of the rat. | Drug metabolism and disposition: the biological fate of chemicals 20030701 |
In vitro metabolism of midazolam, triazolam, nifedipine, and testosterone by human liver microsomes and recombinant cytochromes p450: role of cyp3a4 and cyp3a5. | Drug metabolism and disposition: the biological fate of chemicals 20030701 |
Cyclosporin C(2) and C(0) concentration monitoring in stable, long-term heart transplant recipients receiving metabolic inhibitors. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20030701 |
The use of oral antifungal agents to treat onychomycosis. | Dermatologic clinics 20030701 |
Evaluation of different calorimetric methods to determine the glass transition temperature and molecular mobility below T(g) for amorphous drugs. | International journal of pharmaceutics 20030618 |
Involvement of CYP3A4, CYP2C8, and CYP2D6 in the metabolism of (R)- and (S)-methadone in vitro. | Drug metabolism and disposition: the biological fate of chemicals 20030601 |
Comparative efficacies of oral ketoconazole and terbinafine for reducing Malassezia population sizes on the skin of Basset Hounds. | Veterinary dermatology 20030601 |
Variations in color. | The Journal of family practice 20030601 |
Gender differences in microsomal metabolic activation of hepatotoxic clivorine in rat. | Chemical research in toxicology 20030601 |
Influence of drugs interacting with CYP3A4 on the pharmacokinetics, pharmacodynamics, and safety of the prandial glucose regulator repaglinide. | Journal of clinical pharmacology 20030601 |
Antifungal compounds from Zanthoxylum chiloperone var. angustifolium. | Phytotherapy research : PTR 20030601 |
Coadministration of tacrolimus and ketoconazole in renal transplant recipients: cost analysis and review of metabolic effects. | Transplantation proceedings 20030601 |
Lithium gluconate 8% vs ketoconazole 2% in the treatment of seborrhoeic dermatitis: a multicentre, randomized study. | The British journal of dermatology 20030601 |
Clotrimazole, ketoconazole, and clodinafop-propargyl as potent growth inhibitors of equine Babesia parasites during in vitro culture. | The Journal of parasitology 20030601 |
Candidiasis (vulvovaginal). | Clinical evidence 20030601 |
Identification of the cytochrome P450 enzymes involved in the N-oxidation of voriconazole. | Drug metabolism and disposition: the biological fate of chemicals 20030501 |
Expression of the human CYP3A4 gene in the small intestine of transgenic mice: in vitro metabolism and pharmacokinetics of midazolam. | Drug metabolism and disposition: the biological fate of chemicals 20030501 |
Quinine 3-hydroxylation as a biomarker reaction for the activity of CYP3A4 in man. | European journal of clinical pharmacology 20030501 |
Anti-Aspergillus activities of plant essential oils and their combination effects with ketoconazole or amphotericin B. | Archives of pharmacal research 20030501 |
Effectiveness and tolerability of a standardized phytodrug derived from Solanum chrysotrichum on Tinea pedis: a controlled and randomized clinical trial. | Planta medica 20030501 |
Modulatory effect of cAMP on fungal ergosterol level and inhibitory activity of azole drugs. | Canadian journal of microbiology 20030501 |
Comparison of in vitro P-glycoprotein screening assays: recommendations for their use in drug discovery. | Journal of medicinal chemistry 20030424 |
Validation of an HPLC method on short columns to assay ketoconazole and formaldehyde in shampoo. | Journal of pharmaceutical and biomedical analysis 20030424 |
Production of progesterone from de novo-synthesized cholesterol in cumulus cells and its physiological role during meiotic resumption of porcine oocytes. | Biology of reproduction 20030401 |
Demonstration of UVB-induced synthesis of 1 alpha,25-dihydroxyvitamin D3 (calcitriol) in human skin by microdialysis. | Archives of dermatological research 20030401 |
Interaction between ketoconazole and almotriptan in healthy volunteers. | Journal of clinical pharmacology 20030401 |
Fluorescent substrates of sister-P-glycoprotein (BSEP) evaluated as markers of active transport and inhibition: evidence for contingent unequal binding sites. | Pharmaceutical research 20030401 |
Differential metabolism of midazolam in mouse liver and intestine microsomes: a comparison of cytochrome P450 activity and expression. | Xenobiotica; the fate of foreign compounds in biological systems 20030401 |
Hepatotoxicity of ketoconazole in Sprague-Dawley rats: glutathione depletion, flavin-containing monooxygenases-mediated bioactivation and hepatic covalent binding. | Xenobiotica; the fate of foreign compounds in biological systems 20030401 |
Effects of novel 17alpha-hydroxylase/C17, 20-lyase (P450 17, CYP 17) inhibitors on androgen biosynthesis in vitro and in vivo. | The Journal of steroid biochemistry and molecular biology 20030401 |
High-content profiling of drug-drug interactions: cellular targets involved in the modulation of microtubule drug action by the antifungal ketoconazole. | Journal of biomolecular screening 20030401 |
Retinoic acid metabolism inhibition by 3-azolylmethyl-1H-indoles and 2, 3 or 5-(alpha-azolylbenzyl)-1H-indoles. | Journal of enzyme inhibition and medicinal chemistry 20030401 |
Prednisone metabolism in recipients of kidney or liver transplants and in lung recipients receiving ketoconazole. | Transplantation 20030327 |
Enhancement of moxidectin bioavailability in lamb by a natural flavonoid: quercetin. | Veterinary parasitology 20030325 |
Randomized, multicenter, phase II trial of two multicomponent regimens in androgen-independent prostate cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030301 |
Metabolism and metabolic inhibition of cilnidipine in human liver microsomes. | Acta pharmacologica Sinica 20030301 |
Apparent mechanism-based inhibition of human CYP3A in-vitro by lopinavir. | The Journal of pharmacy and pharmacology 20030301 |
[Nosocomial urinary infection due to Trichosporon asahii. First two cases in Chile]. | Revista iberoamericana de micologia 20030301 |
[Post traumatic subcutaneous mycosis due to Fusarium solani]. | Revista iberoamericana de micologia 20030301 |
Terbinafine effectiveness in ketoconazole-resistant mucocutaneous candidasis in polyglandular autoimmune syndrome type 1. | The Journal of the Association of Physicians of India 20030301 |
Roles of human liver cytochrome P450 3A4 and 1A2 enzymes in the oxidation of myristicin. | Toxicology letters 20030203 |
Rhabdomyolysis from cytochrome p-450 interaction of ketoconazole and simvastatin in prostate cancer. | The Journal of urology 20030201 |
A murine model of coccidioidal meningitis. | The Journal of infectious diseases 20030201 |
The effect of ketoconazole on the in vivo intestinal permeability of fexofenadine using a regional perfusion technique. | British journal of clinical pharmacology 20030201 |
Steroid synthesis inhibition with ketoconazole and its effect upon the regulation of the hypothalamus-pituitary-adrenal system in healthy humans. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030201 |
Efficacy and safety of low-dose ketoconazole (50 mg) to reduce the cost of cyclosporine in renal allograft recipients. | Transplantation proceedings 20030201 |
Antifungal agents of use in animal health--chemical, biochemical and pharmacological aspects. | Journal of veterinary pharmacology and therapeutics 20030201 |
Coccidiomycosis in a dog. | The Canadian veterinary journal = La revue veterinaire canadienne 20030201 |
[How to manage seborrheic dermatitis]. | Revue medicale de Liege 20030201 |
Identification of novel enzyme-prodrug combinations for use in cytochrome P450-based gene therapy for cancer. | Archives of biochemistry and biophysics 20030101 |
Oxidative activation of acylguanidine prodrugs: intestinal presystemic activation in rats limits absorption and can be inhibited by co-administration of ketoconazole. | Xenobiotica; the fate of foreign compounds in biological systems 20030101 |
Lack of effect of ketoconazole on the pharmacokinetics of rosuvastatin in healthy subjects. | British journal of clinical pharmacology 20030101 |
Antifungal activity of the essential oil of Agastache rugosa Kuntze and its synergism with ketoconazole. | Letters in applied microbiology 20030101 |
A case of infantile acne due to pityrosporum. | Pediatric dermatology 20030101 |
[Conjunctival infection due to penicillium SP]. | Archivos de la Sociedad Espanola de Oftalmologia 20030101 |
[Molecular biological analysis of Tinea faciei caused by a clinically anomalous strain of Trichophyton mentagrophytes]. | Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20030101 |
The effect of granisetron on in vitro metabolism of paclitaxel and docetaxel. | Cancer journal (Sudbury, Mass.) 20030101 |
Seborrheic dermatitis today, gone tomorrow? The link between the biocene and treatment. | Dermatology (Basel, Switzerland) 20030101 |
Randomized, open-labeled, non-inferiority study between ciclopiroxolamine 1% cream and ketoconazole 2% foaming gel in mild to moderate facial seborrheic dermatitis. | Dermatology (Basel, Switzerland) 20030101 |
Ketoconazole in the treatment of prostate cancer. | Clinical journal of oncology nursing 20030101 |
Treatment of cutaneous leishmaniasis with ketoconazole cream. | The Journal of dermatological treatment 20030101 |
Framing the future of antifungals in atopic dermatitis. | Dermatology (Basel, Switzerland) 20030101 |
Tolerance to antidepressant treatment may be overcome by ketoconazole. Report of two cases. | Journal of psychiatric research 20030101 |
Azoles for allergic bronchopulmonary aspergillosis associated with asthma. | The Cochrane database of systematic reviews 20030101 |
[Madura foot (mycetoma)]. | Vestnik khirurgii imeni I. I. Grekova 20030101 |
[Finger agenesis after in utero exposure to ketoconazole: a case report]. | Therapie 20030101 |
Ketoconazole foam--connetics: connetics ketoconazole foam. | Drugs in R&D 20030101 |
In vitro drug-drug interactions with perospirone and concomitantly administered drugs in human liver microsomes. | European journal of drug metabolism and pharmacokinetics 20030101 |
[Vaginal candidiasis--treatment protocols using miconazole and fluconazole]. | Akusherstvo i ginekologiia 20030101 |
Oral manifestations of paracoccidioidomycosis. Report of 21 cases from Argentina. | Mycoses 20030101 |
Fungal peritonitis in 15 patients on continuous ambulatory peritoneal dialysis (CAPD). | Mycoses 20030101 |
Synthesis, in vitro/in vivo antifungal evaluation and structure-activity relationship study of 3(2H)-pyridazinones. | Arzneimittel-Forschung 20030101 |
Occurrence of dermatomycoses and in-vitro therapeutic efficacy of three antifungal drugs on the growth of Epidermophyton floccosum. | Mycopathologia 20030101 |
[Investigation of quantitative and species composition and antifungal drug susceptibility of yeasts isolated from patients with generalized periodontitis complicated by candidosis]. | Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) 20030101 |
[Madura's foot (mycetoma)]. | Chirurgia (Bucharest, Romania : 1990) 20030101 |
Medical treatment of hyperadrenocorticism in the dog. | Australian veterinary journal 20030101 |
Protective effect of ketoconazole against experimentally induced gastric ulcers in rats. | Research communications in molecular pathology and pharmacology 20030101 |
[In vitro sensitivity of Histoplasma capsulatum var. capsulatum to amphotericin B, ketoconazole, itroconazole and fluconazole]. | Revista cubana de medicina tropical 20030101 |
Separation of antifungal chiral drugs by SFC and HPLC: a comparative study. | Journal of biochemical and biophysical methods 20021231 |
Pharmacophore model of drugs involved in P-glycoprotein multidrug resistance: explanation of structural variety (hypothesis). | Journal of medicinal chemistry 20021219 |
Mathematical modelling of antifungal action. | Mycoses 20021201 |
[Observations on the efficacy of Botai ointment in treating dermatosis common among armed forces receiving at-sea training]. | Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20021201 |
Application of semisimultaneous midazolam administration for hepatic and intestinal cytochrome P450 3A phenotyping. | Clinical pharmacology and therapeutics 20021201 |
Prevalence and antifungal susceptibilities of yeast isolates during one year at a university hospital in Turkey. | Journal of chemotherapy (Florence, Italy) 20021201 |
Inhibition of the microsomal metabolism of 1,8-cineole in the common brushtail possum (Trichosurus vulpecula) by terpenes and other chemicals. | Xenobiotica; the fate of foreign compounds in biological systems 20021201 |
National Cancer Institute intramural approach to advanced prostate cancer. | Clinical prostate cancer 20021201 |
Triiodide ion and alizarin red S as two new reagents for the determination of clotrimazole and ketoconazole. | Journal of pharmaceutical and biomedical analysis 20021107 |
Paracoccidioidomycosis: report of 2 cases mimicking squamous cell carcinoma. | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20021101 |
Pharmacokinetics and electrocardiographic pharmacodynamics of artemether-lumefantrine (Riamet) with concomitant administration of ketoconazole in healthy subjects. | British journal of clinical pharmacology 20021101 |
Chromatographic determination of clotrimazole, ketoconazole and fluconazole in pharmaceutical formulations. | Farmaco (Societa chimica italiana : 1989) 20021101 |
Corticosteroids and pregnancy. | Seminars in reproductive medicine 20021101 |
Synthesis of novel water soluble benzylazolium prodrugs of lipophilic azole antifungals. | Bioorganic & medicinal chemistry letters 20021007 |
Sirolimus oral absorption in rats is increased by ketoconazole but is not affected by D-alpha-tocopheryl poly(ethylene glycol 1000) succinate. | The Journal of pharmacology and experimental therapeutics 20021001 |
Interaction of cytochrome P450 3A inhibitors with P-glycoprotein. | The Journal of pharmacology and experimental therapeutics 20021001 |
Preclinical activity of ketoconazole in combination with calcitriol or the vitamin D analogue EB 1089 in prostate cancer cells. | The Journal of urology 20021001 |
Efficacy of ozonized sunflower oil in the treatment of tinea pedis. | Mycoses 20021001 |
Vulvovaginal candidiasis. | BMJ (Clinical research ed.) 20020914 |
Expression of paclitaxel-inactivating CYP3A activity in human colorectal cancer: implications for drug therapy. | British journal of cancer 20020909 |
Putative role of the orphan nuclear receptor SXR (steroid and xenobiotic receptor) in the mechanism of CYP3A4 inhibition by xenobiotics. | The Journal of biological chemistry 20020906 |
Macrophage plasma membrane cholesterol contributes to Brucella abortus infection of mice. | Infection and immunity 20020901 |
In vitro, pharmacokinetic, and pharmacodynamic interactions of ketoconazole and midazolam in the rat. | The Journal of pharmacology and experimental therapeutics 20020901 |
Characterization of quinidine 3-hydroxylation as a probe for the CYP 3A enzyme using a novel capillary electrophoresis technique. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20020901 |
Evaluation of a 15-day screening assay using intact male rats for identifying steroid biosynthesis inhibitors and thyroid modulators. | Toxicological sciences : an official journal of the Society of Toxicology 20020901 |
Ketoconazole suppresses interleukin-4 plus anti-CD40-induced IgE class switching in surface IgE negative B cells from patients with atopic dermatitis. | The Journal of investigative dermatology 20020901 |
Azole susceptibility patterns and genetic relationship among oral Candida strains isolated in the era of highly active antiretroviral therapy. | Journal of acquired immune deficiency syndromes (1999) 20020901 |
Design, synthesis, and biological evaluation of aryloxyethyl thiocyanate derivatives against Trypanosoma cruzi. | Journal of medicinal chemistry 20020829 |
Low dose ketoconazole with replacement doses of hydrocortisone in patients with progressive androgen independent prostate cancer. | The Journal of urology 20020801 |
Corneal ulcer caused by the new fungal species Sarcopodium oculorum. | Journal of clinical microbiology 20020801 |
Ketoconazole potentiates the antitumor effects of nocodazole: In vivo therapy for human tumor xenografts in nude mice. | Molecular carcinogenesis 20020801 |
In vivo measurement of human skin absorption of topically applied substances by a photoacoustic technique. | Physiological measurement 20020801 |
Comparative efficacy of various treatment regimens for androgenetic alopecia in men. | The Journal of dermatology 20020801 |
Randomized trial with itraconazole, ketoconazole and sulfadiazine in paracoccidioidomycosis. | Medical mycology 20020801 |
Role of ketoconazole treatment in urinary-free cortisol-to-cortisone and tetrahydrocortisol-to-tetrahydrocortisone ratios in nonectopic Cushing's syndrome. | Endocrine 20020801 |
Modulation of irinotecan metabolism by ketoconazole. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20020715 |
Determination of ketoconazole in human plasma by high-performance liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020705 |
HPLC-MS/MS analysis of the products generated from all-trans-retinoic acid using recombinant human CYP26A. | Journal of lipid research 20020701 |
Application of modeling and simulation to integrate clinical pharmacology knowledge across a new drug application. | International journal of clinical pharmacology and therapeutics 20020701 |
Ketoconazole and kids. | Postgraduate medicine 20020701 |
[Tinea]. | Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20020701 |
Ketoconazole suppresses prostaglandin E(2)-induced cyclooxygenase-2 expression in human epidermoid carcinoma A-431 cells. | The Journal of investigative dermatology 20020701 |
Protothecal colitis in a German shepherd dog. | Australian veterinary journal 20020701 |
Double-blind antiglucocorticoid treatment in schizophrenia and schizoaffective disorder: a pilot study. | The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20020701 |
Antifungal agents. 10. New derivatives of 1-[(aryl)[4-aryl-1H-pyrrol-3-yl]methyl]-1H-imidazole, synthesis, anti-candida activity, and quantitative structure-analysis relationship studies. | Journal of medicinal chemistry 20020620 |
New regulators of drug sensitivity in the family of yeast zinc cluster proteins. | The Journal of biological chemistry 20020614 |
Cutaneous candidiasis in a dog caused by Candida guilliermondii. | The Veterinary record 20020608 |
Simultaneous determination of ketoconazole and formaldehyde in a shampoo: liquid chromatography method development and validation. | Journal of chromatography. A 20020607 |
Expression profiling in squamous carcinoma cells reveals pleiotropic effects of vitamin D3 analog EB1089 signaling on cell proliferation, differentiation, and immune system regulation. | Molecular endocrinology (Baltimore, Md.) 20020601 |
Single- and multiple-dose pharmacokinetics of bosentan and its interaction with ketoconazole. | British journal of clinical pharmacology 20020601 |
Oral treatments for toenail onychomycosis: a systematic review. | Archives of dermatology 20020601 |
A randomised, single-blind, single-centre clinical trial to evaluate comparative clinical efficacy of shampoos containing ciclopirox olamine (1.5%) and salicylic acid (3%), or ketoconazole (2%, Nizoral) for the treatment of dandruff/seborrhoeic dermatitis. | The Journal of dermatological treatment 20020601 |
Fluconazole versus ketoconazole in the treatment of tinea versicolor. | The Journal of dermatological treatment 20020601 |
In vitro characterization of the inhibitory effects of ketoconazole on metabolic activities of cytochrome P-450 in canine hepatic microsomes. | American journal of veterinary research 20020601 |
7-Benzyloxyquinoline oxidation by P450eryF A245T: finding of a new fluorescent substrate probe. | Chemical research in toxicology 20020601 |
Effects of ketoconazole on progesterone and cAMP production in MA-10 mouse Leydig tumor cells. | Biological & pharmaceutical bulletin 20020601 |
[Intranasal rhinosporidiosis: presentation of the 1st case seen in the Congo]. | Bulletin de la Societe de pathologie exotique (1990) 20020601 |
Chronic administration of verapamil, ketoconazole and carbamazepine: impact on immunological parameters. | International journal of pharmaceutics 20020515 |
Three-dimensional quantitative structure-activity relationships of inhibitors of P-glycoprotein. | Molecular pharmacology 20020501 |
Potential role for the hypothalamo-pituitary-adrenal axis in the conditioned reinforcer-induced reinstatement of extinguished cocaine seeking in rats. | Psychopharmacology 20020501 |
Oral FK 506 blood levels are elevated in pig short bowel model: further investigations with co-administration of an intestinal CYP3A4 inhibitor. | Transplantation proceedings 20020501 |
[Candida infection of the skin and mucous membranes still a topic. Administering azoles with clinical understanding]. | MMW Fortschritte der Medizin 20020409 |
Effects of 3-MeSO2-DDE and some CYP inhibitors on glucocorticoid steroidogenesis in the H295R human adrenocortical carcinoma cell line. | Toxicology in vitro : an international journal published in association with BIBRA 20020401 |
Human CYP3A4 and the metabolism of nefazodone and hydroxynefazodone by human liver microsomes and heterologously expressed enzymes. | European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20020401 |
Ketoconazole increases cocaine and opioid use in methadone maintained patients. | Drug and alcohol dependence 20020401 |
In vitro inhibition of pimozide N-dealkylation by selective serotonin reuptake inhibitors and azithromycin. | Journal of clinical psychopharmacology 20020401 |
Antimicrobial activities of a new schizozygane indoline alkaloid from Schizozygia coffaeoides and the revised structure of isoschizogaline. | Journal of natural products 20020401 |
Black-dot tinea capitis. Patchy hair loss is common in pediatric patients. | Postgraduate medicine 20020401 |
Clinical comparison of the efficacy and tolerability of once daily Canesten with twice daily Nizoral (clotrimazole 1% cream vs. ketoconazole 2% cream) during a 28-day topical treatment of interdigital tinea pedis. | Mycoses 20020401 |
Case report. Nattrassia mangiferae endophthalmitis. | Mycoses 20020401 |
Chronic mucocutaneous candidiasis. | JAAPA : official journal of the American Academy of Physician Assistants 20020401 |
Cyclosporin and ketoconazole interaction for treatment of perianal fistulas in the dog. | Australian veterinary journal 20020401 |
Superficial mycosis superimposing on isolated lichen planus of the lip: a case report and review of the literature. | Cutis 20020401 |
[Identification and antifungal susceptibility of Candida spp isolated from invasive mycoses. Influence of growth inhibition percentage to determine minimal inhibitory concentration]. | Revista medica de Chile 20020401 |
Cyclosporine and ketoconazole for the treatment of perianal fistulas in dogs. | Journal of the American Veterinary Medical Association 20020401 |
Simple high-performance liquid chromatography method for the simultaneous determination of ketoconazole and piperine in rat plasma and hepatocyte culture. | Journal of chromatography. A 20020308 |
Effect of antifungal azoles on the heme detoxification system of malarial parasite. | Journal of biochemistry 20020301 |
Effect of oral ketoconazole on first-pass effect of nifedipine after oral administration in dogs. | Journal of pharmaceutical sciences 20020301 |
Minimal effect of ketoconazole on cyclosporine (SangCyA) oral absorption and first-pass metabolism in rats: evidence of a significant vehicle effect on SangCyA absorption. | Biopharmaceutics & drug disposition 20020301 |
Multicenter Brazilian study of oral Candida species isolated from AIDS patients. | Memorias do Instituto Oswaldo Cruz 20020301 |
Cytochrome P450 enzymes contributing to demethylation of maprotiline in man. | Pharmacology & toxicology 20020301 |
Identification of the human P450 enzymes involved in the in vitro metabolism of the synthetic steroidal hormones Org 4060 and Org 30659. | Xenobiotica; the fate of foreign compounds in biological systems 20020201 |
Infectious keratitis in orthokeratology. | Clinical & experimental ophthalmology 20020201 |
Ring substituted 3-phenyl-1-(2-pyrazinyl)-2-propen-1-ones as potential photosynthesis-inhibiting, antifungal and antimycobacterial agents. | Farmaco (Societa chimica italiana : 1989) 20020201 |
Effect of multiple dosing of ketoconazole on pharmacokinetics of midazolam, a cytochrome P-450 3A substrate in beagle dogs. | Drug metabolism and disposition: the biological fate of chemicals 20020101 |
Peppermint oil enhances cyclosporine oral bioavailability in rats: comparison with D-alpha-tocopheryl poly(ethylene glycol 1000) succinate (TPGS) and ketoconazole. | Journal of pharmaceutical sciences 20020101 |
CYP3A4-mediated hepatic metabolism of the HIV-1 protease inhibitor saquinavir in vitro. | Xenobiotica; the fate of foreign compounds in biological systems 20020101 |
Interventions for treating oral candidiasis for patients with cancer receiving treatment. | The Cochrane database of systematic reviews 20020101 |
Comparison of two methods for antifungal susceptibility testing of Trichophyton rubrum. | European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20020101 |
Mycetoma caused by Fusarium solani with osteolytic lesions on the hand: case report. | Mycopathologia 20020101 |
A unique case of bladder mycetoma. | Tropical doctor 20020101 |
Pathology case of the month. Chronic leg ulcer in a missionary worker. Cutaneous leishmaniasis. | The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society 20020101 |
Ectopic ACTH-syndrome due to a thymic carcinoid tumor. | Acta clinica Belgica 20020101 |
More economical use of cyclosporine through combination drug therapy. | Journal of the American Animal Hospital Association 20020101 |
Sustained release bioadhesive effervescent ketoconazole microcapsules tabletted for vaginal delivery. | Journal of microencapsulation 20020101 |
Post-antifungal effect and effects of sub-MIC concentrations on previously treated Candida spp.: influence of exposure time and concentration. | Scandinavian journal of infectious diseases 20020101 |
Euclidean and fractal computer-assisted corneofungimetry: a comparison of 2% ketoconazole and 1% terbinafine topical formulations. | Dermatology (Basel, Switzerland) 20020101 |
A case of confluent and reticulated papillomatosis responsive to ketoconazole cream. | Nihon Ishinkin Gakkai zasshi = Japanese journal of medical mycology 20020101 |
A double-blind placebo-controlled study of ketoconazole + desonide gel combination in the treatment of facial seborrheic dermatitis. | Dermatology (Basel, Switzerland) 20020101 |
Efficacy and skin tolerability of Saliker in the treatment of dandruff. | European journal of dermatology : EJD 20020101 |
Antifungal topical therapy in oral chronic candidosis. A comparative study. | Medicina oral : organo oficial de la Sociedad Espanola de Medicina Oral y de la Academia Iberoamericana de Patologia y Medicina Bucal 20020101 |
Desloratadine has no clinically relevant electrocardiographic or pharmacodynamic interactions with ketoconazole. | Clinical pharmacokinetics 20020101 |
Ketoconazole potentiates terfenadine-induced apoptosis in human Hep G2 cells through inhibition of cytochrome p450 3A4 activity. | Journal of cellular biochemistry 20020101 |
Atopic dermatitis with mononuclear phagocytic activity deficiency. | Allergologia et immunopathologia 20020101 |
A multicenter randomized trial of ketoconazole 2% and zinc pyrithione 1% shampoos in severe dandruff and seborrheic dermatitis. | Skin pharmacology and applied skin physiology 20020101 |
Efficacy and skin tolerability of saliker in the treatment of dandruff. | European journal of dermatology : EJD 20020101 |
Low dose ketoconazole therapy and thyroid functions in rats. | Acta medica (Hradec Kralove) 20020101 |
The preventive effect of ketoconazole on experimental metastasis from a human pancreatic carcinoma may be related to its effect on prostaglandin synthesis. | International journal of gastrointestinal cancer 20020101 |
Invitro drug sensitivity of Trichophyton species against griseofulvin and ketoconazole. | Hindustan antibiotics bulletin 20020101 |
Ectopic adrenocorticotropic hormone syndrome caused by metastatic carcinoma of the prostate: therapeutic response to ketoconazole. | Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists 20020101 |
Toward a novel metal-based chemotherapy against tropical diseases. 6. Synthesis and characterization of new copper(II) and gold(I) clotrimazole and ketoconazole complexes and evaluation of their activity against Trypanosoma cruzi. | Inorganic chemistry 20011231 |
Fatal aplastic anemia during treatment with ketoconazole. | The American journal of medicine 20011215 |
No evidence of oxidant events in amphotericin B cytotoxicity versus L. infantum promastigotes. | Parasite (Paris, France) 20011201 |
Novel steroidal pyrimidyl inhibitors of P450 17 (17 alpha-hydroxylase/C17-20-lyase). | Archiv der Pharmazie 20011201 |
Effects of ketoconazole on oestrus cycle and convulsant action of pentylenetetrazol in mice. | Pharmacology & toxicology 20011201 |
Diazinon is activated by CYP2C19 in human liver. | Toxicology and applied pharmacology 20011115 |
Enhanced antifungal activity of ketoconazole by Euphorbia characias latex against Candida albicans. | Journal of ethnopharmacology 20011101 |
Quantitative liquid chromatography/mass spectrometry/mass spectrometry warfarin assay for in vitro cytochrome P450 studies. | Analytical biochemistry 20011101 |
Importance of inhibin B in the regulation of FSH secretion in the human male. | The Journal of clinical endocrinology and metabolism 20011101 |
Effects of azoles on human acute myelogenous leukemia blasts and T lymphocytes derived from acute leukemia patients with chemotherapy-induced cytopenia. | International immunopharmacology 20011101 |
Improved responsiveness of PCOS patients to clomiphene after CYP17a inhibitor. | Journal of assisted reproduction and genetics 20011101 |
Gene amplification in amphotericin B-resistant Leishmania tarentolae. | Experimental parasitology 20011101 |
Relative contribution of CYP3A to amitriptyline clearance in humans: in vitro and in vivo studies. | Journal of clinical pharmacology 20011001 |
A clinical case of canine mycotic pneumonia. | Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20011001 |
Comparative efficacy of ketoconazole and fluconazole in the treatment of pityriasis versicolor: a one year follow-up study. | The Journal of dermatology 20011001 |
Ketoconazole and Flutamide in the treatment of disseminated intravascular clotting from prostate cancer: a case report and review. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20011001 |
Effect of pharmacotechnical design on the in vitro interaction of ketoconazole tablets with non-systemic antacids. | International journal of pharmaceutics 20010911 |
[Spondylodiscitis due to Histoplasma duboisii. Report of two cases and review of the literature]. | Neuro-Chirurgie 20010901 |
7-Deoxyloganin 7-hydroxylase in Lonicera japonica cell cultures. | Phytochemistry 20010901 |
Post-antifungal effect of polyene, azole and DNA-analogue agents against oral Candida albicans and Candida tropicalis isolates in HIV disease. | Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20010901 |
A simple algorithm for designing group sequential clinical trials. | Biometrics 20010901 |
Lack of effect of reboxetine on cardiac repolarization. | Clinical pharmacology and therapeutics 20010901 |
Medical treatment of canine pituitary-dependent hyperadrenocorticism (Cushing's disease). | The Veterinary clinics of North America. Small animal practice 20010901 |
Severe respiratory failure secondary to Cushing's myopathy. | Journal of endocrinological investigation 20010901 |
Oral histoplasmosis. | The Journal of the Association of Physicians of India 20010901 |
Comparative study of the efficacy of oral ketoconazole with intra-lesional meglumine antimoniate (Glucantime) for the treatment of cutaneous leishmaniasis. | The Journal of dermatological treatment 20010901 |
Pulmonary candidiasis caused by Candida albicans in a Greek tortoise (Testudo graeca) and treatment with intrapulmonary amphotericin B. | Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20010901 |
Cyclosporin immunosuppression of sheep: pharmacokinetics and allograft survival. | Veterinary immunology and immunopathology 20010830 |
Primary culture system of adrenocortical cells from dogs to evaluate direct effects of chemicals on steroidogenesis. | Toxicology 20010828 |
3-Phenyl-5-acyloxymethyl-2H,5H-furan-2-ones: synthesis and biological activity of a novel group of potential antifungal drugs. | Journal of medicinal chemistry 20010816 |
Ketoconazole-induced conformational changes in the active site of cytochrome P450eryF. | Journal of molecular biology 20010803 |
State-dependent block of rabbit vascular smooth muscle delayed rectifier and Kv1.5 channels by inhibitors of cytochrome P450-dependent enzymes. | The Journal of pharmacology and experimental therapeutics 20010801 |
Rationale for combination ketoconazole/ vitamin D treatment of prostate cancer. | Urology 20010801 |
Modulation of the cytochrome P450-mediated metabolism of ifosfamide by ketoconazole and rifampin. | Clinical pharmacology and therapeutics 20010801 |
A systematic review of the effectiveness of antifungal drugs for the prevention and treatment of oropharyngeal candidiasis in HIV-positive patients. | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20010801 |
Application of capillary zone electrophoresis with off-line solid-phase extraction to in vitro metabolism studies of antifungals. | Electrophoresis 20010801 |
Ketoconazole suppresses food restriction-induced increases in heroin self-administration in rats: sex differences. | Experimental and clinical psychopharmacology 20010801 |
Characterization of amorphous ketoconazole using modulated temperature differential scanning calorimetry. | Journal of pharmaceutical sciences 20010801 |
Arthroderma benhamiae infection in a rabbit. | The Journal of veterinary medical science 20010801 |
[Modern local therapy of foot mycoses in servicemen]. | Voenno-meditsinskii zhurnal 20010801 |
Adsorptive behavior and electrochemical determination of the anti-fungal agent ketoconazole. | Fresenius' journal of analytical chemistry 20010801 |
Uptake of Malassezia furfur by human dermal fibroblasts: effect of ketoconazole and cytoskeleton inhibitors. | Archives of dermatological research 20010801 |
Heterogeneity in antifungal susceptibility of clones of Candida albicans isolated on single and sequential visits from a HIV-infected southern Chinese cohort. | Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20010701 |
Effect of an extract of the root of Scutellaria baicalensis and its flavonoids on aflatoxin B1 oxidizing cytochrome P450 enzymes. | Planta medica 20010701 |
Ca(2+) transport into an intracellular acidic compartment of Candida parapsilosis. | FEBS letters 20010629 |
Application to drug-food interactions of living cells as in vitro model expressing cytochrome P450 activity: enzyme inhibition by lemon juice. | Talanta 20010621 |
Oropharyngeal candidiasis in patients with human immunodeficiency virus: correlation of clinical outcome with in vitro resistance, serum azole levels, and immunosuppression. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010601 |
Arachidonic acid directly activates members of the mitogen-activated protein kinase superfamily in rabbit proximal tubule cells. | Kidney international 20010601 |
Aromatization mediates testosterone's short-term feedback restraint of 24-hour endogenously driven and acute exogenous gonadotropin-releasing hormone-stimulated luteinizing hormone and follicle-stimulating hormone secretion in young men. | The Journal of clinical endocrinology and metabolism 20010601 |
Photo quiz. Congenital cutaneous candidiasis. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20010601 |
Successful treatment of Acanthamoeba meningitis with combination oral antimicrobials. | The Pediatric infectious disease journal 20010601 |
Systemic ketoconazole is an effective treatment of atopic dermatitis with IgE-mediated hypersensitivity to yeasts. | Allergy 20010601 |
Temporary remission of disseminated paecilomycosis in a German shepherd dog treated with ketoconazole. | Journal of the South African Veterinary Association 20010601 |
[In vitro antifungal susceptibility of dematiaceous filamentous fungi using the E-test]. | Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia 20010601 |
The effect of gut metabolism on tacrolimus bioavailability in renal transplant recipients. | Transplantation 20010515 |
Mechanism of action of anti-proliferative lysophospholipid analogues against the protozoan parasite Trypanosoma cruzi: potentiation of in vitro activity by the sterol biosynthesis inhibitor ketoconazole. | The Journal of antimicrobial chemotherapy 20010501 |
Effect of inoculum form on in vitro antifungal susceptibilities of Aspergillus spp. | The Journal of antimicrobial chemotherapy 20010501 |
Low salivary cortisol levels and aggressive behavior. | Archives of general psychiatry 20010501 |
The interaction of saquinavir (soft gelatin capsule) with ketoconazole, erythromycin and rifampicin: comparison of the effect in healthy volunteers and in HIV-infected patients. | European journal of clinical pharmacology 20010501 |
Metabolism of amiodarone (Part III): identification of rabbit cytochrome P450 isoforms involved in the hydroxylation of mono-N-desethylamiodarone. | Xenobiotica; the fate of foreign compounds in biological systems 20010501 |
[Endemic mycotic infections]. | La Revue du praticien 20010415 |
Liquid chromatographic determination of ketoconazole, a potent inhibitor of CYP3A4-mediated metabolism. | Journal of chromatography. B, Biomedical sciences and applications 20010405 |
Evaluation of the male pubertal onset assay to detect testosterone and steroid biosynthesis inhibitors in CD rats. | Toxicological sciences : an official journal of the Society of Toxicology 20010401 |
Application of the relative activity factor approach in scaling from heterologously expressed cytochromes p450 to human liver microsomes: studies on amitriptyline as a model substrate. | The Journal of pharmacology and experimental therapeutics 20010401 |
Hypokalemia, metabolic alkalosis, and hypertension: Cushing's syndrome in a patient with metastatic prostate adenocarcinoma. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20010401 |
Pharmacokinetics of cyclosporine in heart transplant recipients receiving metabolic inhibitors. | The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation 20010401 |
Interaction of two novel 14-epivitamin D3 analogs with vitamin D3 receptor-retinoid X receptor heterodimers on vitamin D3 responsive elements. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010401 |
Successful treatment of visceral leishmaniasis with allopurinol plus ketoconazole in an infant who developed pancreatitis caused by meglumine antimoniate. | The Pediatric infectious disease journal 20010401 |
Ranitidine-related Stevens-Johnson syndrome in patients with severe liver diseases: a report of two cases. | Journal of gastroenterology and hepatology 20010401 |
Preparation and physical characterization of alginate microparticles using air atomization method. | Drug development and industrial pharmacy 20010401 |
Hard palate perforation: an unusual finding in paracoccidioidomycosis. | International journal of dermatology 20010401 |
Drug sensitivity of Candida yeast isolated from patients with allergic diseases. | Bulletin of experimental biology and medicine 20010401 |
Treatments for common superficial fungal infections. | Dermatology nursing 20010401 |
Coadministration of ketoconazole and cyclosporine for kidney transplant recipients: long-term follow-up and study of metabolic consequences. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20010301 |
Clinical inquiries. What is the best oral antifungal medication for tinea capitis? | The Journal of family practice 20010301 |
A new class of nonsteroidal aromatase inhibitors: design and synthesis of chromone and xanthone derivatives and inhibition of the P450 enzymes aromatase and 17 alpha-hydroxylase/C17,20-lyase. | Journal of medicinal chemistry 20010301 |
Treatment for coccidioidomycosis in pregnancy? | Postgraduate medicine 20010301 |
Fatal liver failure due to ketoconazole treatment of a girl with Cushing's syndrome. | Journal of pediatric endocrinology & metabolism : JPEM 20010301 |
[Ocular parasitoses and mycoses: cases diagnosed in the Central University Hospital of Sfax between 1996 and 1999]. | Bulletin de la Societe de pathologie exotique (1990) 20010301 |
Effects of ketoconazole on the acquisition of intravenous cocaine self-administration under different feeding conditions in rats. | Psychopharmacology 20010301 |
Emedastine-ketoconazole: pharmacokinetic and pharmacodynamic interactions in healthy volunteers. | International journal of clinical pharmacology and therapeutics 20010301 |
In vitro/in vivo scaling of alprazolam metabolism by CYP3A4 and CYP3A5 in humans. | Biopharmaceutics & drug disposition 20010301 |
Aminoglutethimide, a steroidogenesis inhibitor, abolishes hormonal induction of ornithine decarboxylase in steroidogenic tissues: evidence for its role as cAMP-dependent protein kinase inhibitor. | Biochemical and biophysical research communications 20010216 |
Muting of androgen negative feedback unveils impoverished gonadotropin-releasing hormone/luteinizing hormone secretory reactivity in healthy older men. | The Journal of clinical endocrinology and metabolism 20010201 |
CYP3A4 is the major CYP isoform mediating the in vitro hydroxylation and demethylation of flunitrazepam. | Drug metabolism and disposition: the biological fate of chemicals 20010201 |
Modulation of P450 CYP3A4-dependent metabolism by P-glycoprotein: implications for P450 phenotyping. | The Journal of pharmacology and experimental therapeutics 20010201 |
A novel sequence element is involved in the transcriptional regulation of expression of the ERG1 (squalene epoxidase) gene in Saccharomyces cerevisiae. | European journal of biochemistry 20010201 |
Lack of effect of a single dose of ketoconazole on the pharmacokinetics of citalopram. | Pharmacotherapy 20010201 |
Determination of minumum inhibitory concentrations of Candida species isolated from vaginal swab specimens by using broth macrodilution and E-test. | Journal of chemotherapy (Florence, Italy) 20010201 |
Effect of ketoconazole, itraconazole and fluconazole on the gastrointestinal colonization of mice by Candida albicans. | Journal of chemotherapy (Florence, Italy) 20010201 |
Ketoconazole in bipolar patients with depressive symptoms: a case series and literature review. | Bipolar disorders 20010201 |
Species difference in stereoselective involvement of CYP3A in the mono-N-dealkylation of disopyramide. | Xenobiotica; the fate of foreign compounds in biological systems 20010201 |
Indications for the involvement of a CYP3A-like iso-enzyme in the metabolism of chlorobornane (Toxaphene) congeners in seals from inhibition studies with liver microsomes. | Aquatic toxicology (Amsterdam, Netherlands) 20010101 |
Physical stabilisation of amorphous ketoconazole in solid dispersions with polyvinylpyrrolidone K25. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20010101 |
Meiosis-activating sterol and the maturation of isolated mouse oocytes. | Biology of reproduction 20010101 |
The combination of oral amphotericin B with azoles prevents the emergence of resistant Candida species in neutropenic patients. | British journal of haematology 20010101 |
Studies on the metabolism of troglitazone to reactive intermediates in vitro and in vivo. Evidence for novel biotransformation pathways involving quinone methide formation and thiazolidinedione ring scission. | Chemical research in toxicology 20010101 |
Endogenous lipoid pneumonia associated with undifferentiated connective tissue disease (UCTD). | Medical science monitor : international medical journal of experimental and clinical research 20010101 |
[The yeast fungus Malassezia: pathogen, pathogenesis and therapy]. | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20010101 |
Differential regulation of gonadotropin secretion by testosterone in the human male: absence of a negative feedback effect of testosterone on follicle-stimulating hormone secretion. | The Journal of clinical endocrinology and metabolism 20010101 |
Effect of ketoconazole 1% and 2% shampoos on severe dandruff and seborrhoeic dermatitis: clinical, squamometric and mycological assessments. | Dermatology (Basel, Switzerland) 20010101 |
Investigation of ketoconazole copper(II) and cobalt(II) complexes and their spectrophotometric applications. | Journal of AOAC International 20010101 |
Ketoconazole and pulmonary failure after esophagectomy: a prospective clinical trial. | Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20010101 |
[Antifungal susceptibility of emerging yeast pathogens]. | Enfermedades infecciosas y microbiologia clinica 20010101 |
Systemic ketoconazole for yeast allergic patients with atopic dermatitis. | Journal of the European Academy of Dermatology and Venereology : JEADV 20010101 |
A novel extractionless hplc fluorescence method for the determination of glyburide in the human plasma: application to a bioequivalence study. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20010101 |
Guess what! Tinea capitis by Trichophyton schöenleinii. | European journal of dermatology : EJD 20010101 |
A preliminary study on the feasibility of an automated blood-sampling system in conjunction with liquid chromatography/mass spectrometry. | Rapid communications in mass spectrometry : RCM 20010101 |
Azoles for allergic bronchopulmonary aspergillosis associated with asthma. | The Cochrane database of systematic reviews 20010101 |
Case report. Disseminated tinea of the verrucous type due to epidermophyton floccosum. | Mycoses 20010101 |
A plea to bridge the gap between antifungals and the management of onychomycosis. | American journal of clinical dermatology 20010101 |
[Apropos of 'Onychomycoses caused by non-dermatophytic filamentous fungi in Cádiz']. | Enfermedades infecciosas y microbiologia clinica 20010101 |
[Antitoxic properties of hepazan--a novel inducer of microsomal enzyme system]. | Eksperimental'naia i klinicheskaia farmakologiia 20010101 |
[Acanthamoeba lesions of the cornea]. | Vestnik oftalmologii 20010101 |
Successful treatment of CAPD peritonitis caused by rhodotorula mucilaginosa. | Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 20010101 |
Lack of CYP3A4 inhibition by grapefruit juice and ketoconazole upon clozapine administration in vivo. | Drug metabolism and drug interactions 20010101 |
[Vulvovaginal candidiasis in childhood--diagnostic and therapeutic results]. | Akusherstvo i ginekologiia 20010101 |
Recovery of bone mineral density after surgical cure, but not by ketoconazole treatment, in Cushing's syndrome. | Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 20010101 |
[Vaginal candidiasis: etiology and sensitivity profile to antifungal agents in clinical use]. | Revista Argentina de microbiologia 20010101 |
Drug susceptibility testing of Malassezia furfur strains to antifungal agents. | Folia medica 20010101 |
[The sensitivity to ketoconazole of Candida strains isolated from the digestive tract ontocenoses in children]. | Wiadomosci parazytologiczne 20010101 |
Antiandrogenic effects of novel androgen synthesis inhibitors on hormone-dependent prostate cancer. | Cancer research 20001201 |
Lipoproteins regulate expression of the steroidogenic acute regulatory protein (StAR) in mouse adrenocortical cells. | The Journal of biological chemistry 20001124 |
The involvement of flavin-containing monooxygenase but not CYP3A4 in metabolism of itopride hydrochloride, a gastroprokinetic agent: comparison with cisapride and mosapride citrate. | Drug metabolism and disposition: the biological fate of chemicals 20001001 |
Identification of cytochrome P4503A as the major subfamily responsible for the metabolism of roquinimex in man. | Xenobiotica; the fate of foreign compounds in biological systems 20000901 |
3-Phenyl-5-methyl-2H,5H-furan-2-ones: tuning antifungal activity by varying substituents on the phenyl ring. | Bioorganic & medicinal chemistry letters 20000821 |
Comparison of three different in vitro mutation assays used for the investigation of cytochrome P450-mediated mutagenicity of nitro-polycyclic aromatic hydrocarbons. | Mutation research 20000323 |
Modulation by drugs of human hepatic sodium-dependent bile acid transporter (sodium taurocholate cotransporting polypeptide) activity. | The Journal of pharmacology and experimental therapeutics 19991201 |
Cushing's syndrome in pregnancy treated by ketoconazole: case report and review of the literature. | Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 19990601 |
In vitro susceptibilities of clinical yeast isolates to the new antifungal eberconazole compared with their susceptibilities to clotrimazole and ketoconazole. | Antimicrobial agents and chemotherapy 19990501 |
Interplay between CYP3A-mediated metabolism and polarized efflux of terfenadine and its metabolites in intestinal epithelial Caco-2 (TC7) cell monolayers. | Pharmaceutical research 19990501 |
Cytochrome P450 3A4 in vivo ketoconazole competitive inhibition: determination of Ki and dangers associated with high clearance drugs in general. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 19990101 |
Ketoconazole reduces low dose cocaine self-administration in rats. | Drug and alcohol dependence 19981201 |
Characterization of the cloned human intermediate-conductance Ca2+-activated K+ channel. | The American journal of physiology 19980901 |
Synergy of nitric oxide and azoles against Candida species in vitro. | Antimicrobial agents and chemotherapy 19980901 |
Blockade of HERG and Kv1.5 by ketoconazole. | The Journal of pharmacology and experimental therapeutics 19980801 |
Trazodone is metabolized to m-chlorophenylpiperazine by CYP3A4 from human sources. | Drug metabolism and disposition: the biological fate of chemicals 19980601 |
Kinetic characterization and identification of the enzymes responsible for the hepatic biotransformation of adinazolam and N-desmethyladinazolam in man. | The Journal of pharmacy and pharmacology 19980301 |
Reduction of oxysterol levels up-regulates HMG-CoA reductase activity in rat liver. | Atherosclerosis 19970601 |
Selective biotransformation of the human immunodeficiency virus protease inhibitor saquinavir by human small-intestinal cytochrome P4503A4: potential contribution to high first-pass metabolism. | Drug metabolism and disposition: the biological fate of chemicals 19970201 |
Combined use of astemizole and ketoconazole resulting in torsade de pointes. | Journal of the Formosan Medical Association = Taiwan yi zhi 19970201 |
Hepatic injury during ketoconazole therapy in patients with onychomycosis: a controlled cohort study. | Hepatology (Baltimore, Md.) 19970101 |
In vitro synergistic activity of ketoconazole with valproic acid against Candida species. | Arzneimittel-Forschung 19960901 |
Human reductive halothane metabolism in vitro is catalyzed by cytochrome P450 2A6 and 3A4. | Drug metabolism and disposition: the biological fate of chemicals 19960901 |
Paranoid delusions caused by ketoconazole. | International journal of dermatology 19960101 |
Treatment of New World cutaneous and mucosal leishmaniases. | Clinics in dermatology 19960101 |
Antifungal agents. 9. 3-Aryl-4-[alpha-(1H-imidazol-1-yl)arylmethyl]pyrroles: a new class of potent anti-Candida agents. | Journal of medicinal chemistry 19951013 |
In vitro susceptibility of filamentous fungi to itraconazole. | Indian journal of pathology & microbiology 19951001 |
Synthesis and antifungal activity of new azole derivatives containing an N-acylmorpholine ring. | Journal of medicinal chemistry 19950929 |
Mechanism for species-specific induction of Leydig cell tumors in rats by lansoprazole. | Fundamental and applied toxicology : official journal of the Society of Toxicology 19950701 |
Novel steroidal inhibitors of human cytochrome P45017 alpha (17 alpha-hydroxylase-C17,20-lyase): potential agents for the treatment of prostatic cancer. | Journal of medicinal chemistry 19950623 |
In vitro activity of D0870 compared with those of other azoles against fluconazole-resistant Candida spp. | Antimicrobial agents and chemotherapy 19950401 |
Selectivity of isoprenoid-containing imidazole antifungal compounds for sterol 14-demethylase P450 (P450(14)DM) and 7-ethoxycoumarin O-deethylase P450 of rat liver microsomes. | Biochemical pharmacology 19941018 |
Hypersensitivity to ketoconazole. | Annals of allergy 19941001 |
Pneumocystis carinii is resistant to imidazole antifungal agents. | Antimicrobial agents and chemotherapy 19940801 |
Derivatives of a novel cyclopeptolide. 1. Synthesis, antifungal activity, and structure-activity relationships. | Journal of medicinal chemistry 19940624 |
Selective inhibition of mammalian lanosterol 14 alpha-demethylase by RS-21607 in vitro and in vivo. | Biochemistry 19940419 |
Antimicrobial and antitumoral activities of 6-allyl-5,6-dihydro-5-hydroxypyran-2-one, a lactone produced by a new Drechslera species. | Die Pharmazie 19940401 |
Ro 09-1470 is a selective inhibitor of P-450 lanosterol C-14 demethylase of fungi. | Antimicrobial agents and chemotherapy 19931201 |
Effects of the combination of ketoconazole and calmodulin inhibitors against Candida albicans in vitro. Short communication. | Arzneimittel-Forschung 19930901 |
Antifungal agents. VI. In vitro antifungal activities of halobenzoyl esters of cis- and trans-[2-(1,1'-biphenyl-4-yl)-2-(1H-imidazol-1-ylmethyl)-1,3- dioxolan-4-yl]carbinols. | Farmaco (Societa chimica italiana : 1989) 19930801 |
Synthesis and structure-activity relationships of phenyl-substituted benzylamine antimycotics: a novel benzylbenzylamine antifungal agent for systemic treatment. | Journal of medicinal chemistry 19930723 |
Selective inhibition of mammalian lanosterol 14 alpha-demethylase: a possible strategy for cholesterol lowering. | Journal of medicinal chemistry 19930723 |
Effects of the combination of ketoconazole and calcium channel antagonists against Candida albicans in vitro. | Arzneimittel-Forschung 19930701 |
Ventricular fibrillation secondary to itraconazole induced hypokalaemia. | The Journal of infection 19930501 |
Ketoconazole induced papilledema. | Acta ophthalmologica 19930401 |
Torsades de pointes after terfenadine-itraconazole interaction. | BMJ (Clinical research ed.) 19930116 |
Erythromycin and ketoconazole (Nizoral) associated with terfenadine (Seldane)-induced ventricular arrhythmias. | General dentistry 19930101 |
Evidence for CYP3A-mediated N-deethylation of amiodarone in human liver microsomal fractions. | Drug metabolism and disposition: the biological fate of chemicals 19930101 |
[Treatment with terfenadine and ketoconazole or itraconazole can cause torsades de pointes ventricular tachycardia]. | Duodecim; laaketieteellinen aikakauskirja 19930101 |
Drug-induced gynecomastia. | Pharmacotherapy 19930101 |
Antifungal activity of meridine, a natural product from the marine sponge Corticium sp. | Journal of natural products 19921101 |
Antibacterial and antifungal agents. XV. Synthesis and antifungal activity of structural analogues of bifonazole and ketoconazole. | Archiv der Pharmazie 19921101 |
Stereoisomers of ketoconazole: preparation and biological activity. | Journal of medicinal chemistry 19920724 |
Reduction of chromium(VI) to chromium(V) by rat liver cytosolic and microsomal fractions: is DT-diaphorase involved? | Carcinogenesis 19920701 |
Torsades de Pointes after treatment with terfenadine and ketoconazole. | European heart journal 19920701 |
Comparative study of six antifungal treatments in an experimental model of murine cryptococcosis. | European journal of epidemiology 19920501 |
Uroporphyrinogen oxidation catalyzed by reconstituted cytochrome P450IA2. | Archives of biochemistry and biophysics 19920501 |
In vitro activity of cloconazole, sulconazole, butoconazole, isoconazole, fenticonazole, and five other antifungal agents against clinical isolates of Candida albicans and Candida spp. | Mycopathologia 19920401 |
The mechanism of bioactivation and antigen formation of amodiaquine in the rat. | Biochemical pharmacology 19920401 |
Placebo-controlled clinical trial of sodium stibogluconate (Pentostam) versus ketoconazole for treating cutaneous leishmaniasis in Guatemala. | The Journal of infectious diseases 19920301 |
Acute renal failure after liver transplantation in patients treated with cyclosporine. | Transplantation proceedings 19920201 |
Ketoconazole and high-dose methylprednisolone predisposing to cyclosporine-induced seizures: report of 3 cases. | Acta haematologica 19920101 |
Synthesis, specificity, and antifungal activity of inhibitors of the Candida albicans delta 24-sterol methyltransferase. | Journal of medicinal chemistry 19920101 |
Myopathy associated with ketoconazole treatment. | American journal of diseases of children (1960) 19910901 |
Ketoconazole-induced fulminant hepatitis necessitating liver transplantation. | Journal of the American Academy of Dermatology 19910801 |
Drug induced suicidal ideation. | The Israel journal of psychiatry and related sciences 19910101 |
Torsades de pointes occurring in association with terfenadine use. | JAMA 19901205 |
Effects of pentamidine alone and in combination with ketoconazole or itraconazole on the growth of Candida albicans. | Antimicrobial agents and chemotherapy 19901201 |
Massive hepatic enlargement with fatty change associated with ketoconazole. | DICP : the annals of pharmacotherapy 19901201 |
Cyclosporine and itraconazole interaction in heart and lung transplant recipients. | Annals of internal medicine 19900815 |
Efficacy of ketoconazole against Leishmania braziliensis panamensis cutaneous leishmaniasis. | The American journal of medicine 19900801 |
Arterial hypertension as a complication of prolonged ketoconazole treatment. | Journal of hypertension. Supplement : official journal of the International Society of Hypertension 19891201 |
Adverse psychiatric reaction to ketoconazole. | The American journal of psychiatry 19890701 |
Neurologic complications of ketoconazole therapy for advanced prostatic cancer. | Urology 19890601 |
[Toxic hepatitis caused by ketoconazole: a report of 4 cases]. | Revista paulista de medicina 19890101 |
Studies on antifungal agents. 23. Novel substituted 3,5-diphenyl-3-(1H-imidazol-1-ylmethyl)- 2-alkylisoxazolidine derivatives. | Journal of medicinal chemistry 19881001 |
In-vivo effects of itraconazole on hepatic mixed-function oxidase. | The Journal of antimicrobial chemotherapy 19880201 |
Prolonged jaundice following ketoconazole-induced hepatic injury. | Digestive diseases and sciences 19880201 |
[Cholestatic hepatitis caused by ketoconazole]. | Annales de gastroenterologie et d'hepatologie 19880101 |
Itraconazole and cyclosporin nephrotoxicity. | Lancet (London, England) 19871017 |
Hypertension during high-dose ketoconazole treatment: a probable mineralocorticosteroid effect. | Lancet (London, England) 19870912 |
Antifungal activity of the allylamine derivative terbinafine in vitro. | Antimicrobial agents and chemotherapy 19870901 |
Lysosomotropic agents. 7. Broad-spectrum antifungal activity of lysosomotropic detergents. | Journal of medicinal chemistry 19870801 |
Synthesis and oral antifungal activity of novel azolylpropanolones and related compounds. | Journal of medicinal chemistry 19870601 |
Immune hemolytic anemia associated with ketoconazole therapy. | Clinical pharmacy 19870601 |
Hepatic reactions associated with ketoconazole in the United Kingdom. | British medical journal (Clinical research ed.) 19870214 |
Ketoconazole-induced hepatitis: a case with a definite cause-effect relationship. | Liver 19870201 |
[Hepatic lesions induced by drugs. Report of 26 cases]. | Acta gastroenterologica Latinoamericana 19870101 |
Activity of SM-4470, a new imidazole derivative, against experimental fungal infections. | Antimicrobial agents and chemotherapy 19860901 |
In vitro activity of ketoconazole against herpes simplex virus. | Antimicrobial agents and chemotherapy 19860801 |
Ketoconazole-associated hepatic injury. A clinicopathological study of 55 cases. | Journal of hepatology 19860101 |
Experimental cyclosporine nephrotoxicity: risk of concomitant chemotherapy. | Clinical nephrology 19860101 |
Ketoconazole-induced fulminant hepatitis. | Gut 19850601 |
Activity of UK-49,858, a bis-triazole derivative, against experimental infections with Candida albicans and Trichophyton mentagrophytes. | Antimicrobial agents and chemotherapy 19850501 |
Treatment of canine blastomycosis with amphotericin B and ketoconazole. | Journal of the American Veterinary Medical Association 19840515 |
Hepatic injury associated with ketoconazole therapy. Analysis of 33 cases. | Gastroenterology 19840301 |
Toxic hepatitis following ketoconazole treatment. | Scandinavian journal of infectious diseases 19840101 |
[Ketoconazole-induced hepatitis. Case report]. | Zeitschrift fur Gastroenterologie 19831201 |
[Toxic hepatitis caused by ketoconazole]. | Nederlands tijdschrift voor geneeskunde 19830618 |
Synthesis of (E)-1-(5-chlorothien-2-yl)-2-(1H-imidazol-1-yl)ethanone 2,6-dichlorophenylhydrazone hydrochloride, a novel, orally active antifungal agent. | Journal of medicinal chemistry 19830301 |
[Toxic hepatitis caused by ketoconazole (Nizoral)]. | Nederlands tijdschrift voor geneeskunde 19830219 |
3',5'-cyclic adenosine monophosphate response element binding protein up-regulated cytochrome P450 lanosterol 14alpha-demethylase expression involved in follicle-stimulating hormone-induced mouse oocyte maturation. | Molecular endocrinology (Baltimore, Md.) |