Acetic acid,[[2-[[(2R)-2-amino-3-methyl-1-oxobutyl]amino]-1,1-dimethylethyl]thio]-,(3aS,4R,5S,6S,8R,9R,9aR,10R)-6-ethenyldecahydro-5-hydroxy-4,6,9,10-tetramethyl-1-oxo-3a,9-propano-3aH-cyclopentacycloocten-8-ylester
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Why are most phospholipidosis inducers also hERG blockers? | Archives of toxicology 20171201 |
Novel pleuromutilin derivatives as antibacterial agents: synthesis, biological evaluation and molecular docking studies. | Bioorganic & medicinal chemistry letters 20121001 |
A click chemistry approach to pleuromutilin derivatives, part 2: conjugates with acyclic nucleosides and their ribosomal binding and antibacterial activity. | Journal of medicinal chemistry 20120308 |
Pleuromutilin and its derivatives-the lead compounds for novel antibiotics. | Mini reviews in medicinal chemistry 20120101 |
Antimicrobial susceptibility of Brachyspira hyodysenteriae isolated from 21 Polish farms. | Polish journal of veterinary sciences 20120101 |
Pharmacokinetics and bioavailability of valnemulin in Muscovy ducks (Cairina moschata). | British poultry science 20120101 |
Curative effect of topical treatment of digital dermatitis with a gel containing activated copper and zinc chelate. | The Veterinary record 20111119 |
Species characterization and minimum inhibitory concentration patterns of Brachyspira species isolates from swine with clinical disease. | Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 20111101 |
Antimicrobial susceptibility pattern of Brachyspira intermedia isolates from European layers. | Microbial drug resistance (Larchmont, N.Y.) 20110901 |
Single and dual mutations at positions 2058, 2503 and 2504 of 23S rRNA and their relationship to resistance to antibiotics that target the large ribosomal subunit. | The Journal of antimicrobial chemotherapy 20110901 |
Antimicrobial susceptibility of Brachyspira spp. isolated from commercial laying hens and free-living wild mallards (Anas platyrhynchos). | Avian pathology : journal of the W.V.P.A 20110801 |
A physiologically based pharmacokinetic model for valnemulin in rats and extrapolation to pigs. | Journal of veterinary pharmacology and therapeutics 20110601 |
Pharmacokinetics and bioavailability of valnemulin in broiler chickens. | Journal of veterinary pharmacology and therapeutics 20110601 |
Cloning and characterization of an Armillaria gallica cDNA encoding protoilludene synthase, which catalyzes the first committed step in the synthesis of antimicrobial melleolides. | The Journal of biological chemistry 20110304 |
Characterisation of multiresistant Brachyspira hyodysenteriae isolates from Czech pig farms. | The Veterinary record 20110226 |
Molecularly imprinted solid-phase extraction for the selective determination of valnemulin in feeds with high performance liquid chromatography. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110115 |
Characterization of in vivo-acquired resistance to macrolides of Mycoplasma gallisepticum strains isolated from poultry. | Veterinary research 20110101 |
In vitro antimicrobial susceptibility of Brachyspira hyodysenteriae strains isolated in Japan from 1985 to 2009. | The Journal of veterinary medical science 20101201 |
Preventive effects of valnemulin on lipopolysaccharide-induced acute lung injury in mice. | Inflammation 20101001 |
Mutations in 23S rRNA gene associated with decreased susceptibility to tiamulin and valnemulin in Mycoplasma gallisepticum. | FEMS microbiology letters 20100701 |
Residue depletion of valnemulin in swine tissues after oral administration. | Analytica chimica acta 20100401 |
The pleuromutilin antibiotics: a new class for human use. | Current opinion in investigational drugs (London, England : 2000) 20100201 |
Mutilins derivatives: from veterinary to human-used antibiotics. | Mini reviews in medicinal chemistry 20091001 |
Antimicrobial susceptibility testing of Spanish field isolates of Brachyspira hyodysenteriae. | Research in veterinary science 20090801 |
Valnemulin downregulates nitric oxide, prostaglandin E2, and cytokine production via inhibition of NF-kappaB and MAPK activity. | International immunopharmacology 20090701 |
In vitro antimicrobial activity against 10 North American and European Lawsonia intracellularis isolates. | Veterinary microbiology 20090302 |
Single 23S rRNA mutations at the ribosomal peptidyl transferase centre confer resistance to valnemulin and other antibiotics in Mycobacterium smegmatis by perturbation of the drug binding pocket. | Molecular microbiology 20090301 |
Rapid determination of five antibiotic residues in swine wastewater by online solid-phase extraction-high performance liquid chromatography-tandem mass spectrometry. | Analytical and bioanalytical chemistry 20090201 |
Comprehensive screening and quantification of veterinary drugs in milk using UPLC-ToF-MS. | Analytical and bioanalytical chemistry 20080701 |
[Multiresistant Brachyspira hyodysenteriae in a Dutch sow herd]. | Tijdschrift voor diergeneeskunde 20080701 |
Isolation and characterization of Treponema phagedenis-like spirochetes from digital dermatitis lesions in Swedish dairy cattle. | Acta veterinaria Scandinavica 20080101 |
Tiamulin resistance in porcine Brachyspira pilosicoli isolates. | Research in veterinary science 20060201 |
The efficacy of valnemulin (Econor) in the control of disease caused by experimental infection of calves with Mycoplasma bovis. | Research in veterinary science 20050601 |
Comparison of methods for antimicrobial susceptibility testing and MIC values for pleuromutilin drugs for Brachyspira hyodysenteriae isolated in Germany. | Veterinary microbiology 20040819 |
Decreased susceptibility to tiamulin and valnemulin among Czech isolates of Brachyspira hyodysenteriae. | Journal of medical microbiology 20040401 |
In vitro susceptibility of 21 antimicrobial agents to 37 isolates of Brachyspira hyodysenteriae isolated from pigs in Okinawa Prefecture. | The Journal of veterinary medical science 20040301 |
Antimicrobial susceptibility testing of Australian isolates of Brachyspira hyodysenteriae using a new broth dilution method. | Veterinary microbiology 20020103 |
Treatment of pigs experimentally infected with Mycoplasma hyopneumoniae, Pasteurella multocida, and Actinobacillus pleuropneumoniae with various antibiotics. | Canadian journal of veterinary research = Revue canadienne de recherche veterinaire 20011001 |
Comparison of valnemulin and lincomycin in the treatment of digital dermatitis by individually applied topical spray. | The Veterinary record 20010908 |
The pleuromutilin drugs tiamulin and valnemulin bind to the RNA at the peptidyl transferase centre on the ribosome. | Molecular microbiology 20010901 |
Susceptibility to pleuromutilins in Brachyspira (Serpulina) hyodysenteriae. | Animal health research reviews 20010601 |
Use of valnemulin in the control of Mycoplasma bovis infection under field conditions. | The Veterinary record 20010331 |