Z-Vad(ome)-fmk
| Title | Journal |
|---|---|
| Isoalantolactone induces apoptosis through reactive oxygen species-dependent upregulation of death receptor 5 in human esophageal cancer cells. | Toxicology and applied pharmacology 20180801 |
| Doxorubicin triggers bioenergetic failure and p53 activation in mouse stem cell-derived cardiomyocytes. | Toxicology and applied pharmacology 20180601 |
| Nano-sized iron particles may induce multiple pathways of cell death following generation of mistranscripted RNA in human corneal epithelial cells. | Toxicology in vitro : an international journal published in association with BIBRA 20170801 |
| Quercetin simultaneously induces G(0) /G(1) -phase arrest and caspase-mediated crosstalk between apoptosis and autophagy in human leukemia HL-60 cells. | Environmental toxicology 20170701 |
| Nuclear factor erythroid 2-related factor 2 enhances carcinogenesis by suppressing apoptosis and promoting autophagy in nickel-transformed cells. | The Journal of biological chemistry 20170519 |
| Inhibition of ROS production, autophagy or apoptosis signaling reversed the anticancer properties of Antrodia salmonea in triple-negative breast cancer (MDA-MB-231) cells. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20170501 |
| Apoptosis inducing factor gene depletion inhibits zearalenone-induced cell death in a goat Leydig cell line. | Reproductive toxicology (Elmsford, N.Y.) 20170101 |
| Caspase-Independent Apoptosis Induced by Reperfusion Following Ischemia without Bile Duct Occlusion in Rat Liver. | Biological & pharmaceutical bulletin 20170101 |
| Tetrachlorobenzoquinone Stimulates NLRP3 Inflammasome-Mediated Post-Translational Activation and Secretion of IL-1β in the HUVEC Endothelial Cell Line. | Chemical research in toxicology 20160321 |
| Stimulating basal mitochondrial respiration decreases doxorubicin apoptotic signaling in H9c2 cardiomyoblasts. | Toxicology 20150806 |
| The 5-Lipoxygenase Inhibitor Zileuton Confers Neuroprotection against Glutamate Oxidative Damage by Inhibiting Ferroptosis. | Biological & pharmaceutical bulletin 20150101 |
| Programmed cell death induced by (-)-8,9-dehydroneopeltolide in human promyelocytic leukemia HL-60 cells under energy stress conditions. | Marine drugs 20141101 |
| TRAF2 inhibits TRAIL- and CD95L-induced apoptosis and necroptosis. | Cell death & disease 20141001 |
| Quercetin induces apoptosis by inhibiting MAPKs and TRPM7 channels in AGS cells. | International journal of molecular medicine 20140601 |
| Disuccinyl betulin triggers metacaspase-dependent endonuclease G-mediated cell death in unicellular protozoan parasite Leishmania donovani. | Antimicrobial agents and chemotherapy 20140401 |
| The C-terminal domain of the long form of cellular FLICE-inhibitory protein (c-FLIPL) inhibits the interaction of the caspase 8 prodomain with the receptor-interacting protein 1 (RIP1) death domain and regulates caspase 8-dependent nuclear factor κB (NF-κB) activation. | The Journal of biological chemistry 20140214 |
| Matrix metalloproteinase-9 is involved in chronic lymphocytic leukemia cell response to fludarabine and arsenic trioxide. | PloS one 20140101 |
| Aneugenic potential of the anticancer drugs melphalan and chlorambucil. The involvement of apoptosis and chromosome segregation regulating proteins. | Journal of applied toxicology : JAT 20130701 |
| Acute phorbol ester treatment inhibits thapsigargin-induced cell death in porcine aortic smooth muscle cells. | European journal of pharmacology 20120705 |
| Increased expression of stefin B in the nucleus of T98G astrocytoma cells delays caspase activation. | Frontiers in molecular neuroscience 20120101 |
| Mechanisms involved in lipid accumulation and apoptosis induced by 1-nitropyrene in Hepa1c1c7 cells. | Toxicology letters 20111030 |
| Polyalkoxybenzenes from plants. 5. Parsley seed extract in synthesis of azapodophyllotoxins featuring strong tubulin destabilizing activity in the sea urchin embryo and cell culture assays. | Journal of medicinal chemistry 20111027 |
| Generation of 'Unnatural Natural Product' library and identification of a small molecule inhibitor of XIAP. | Bioorganic & medicinal chemistry 20110715 |
| MAGUKs, scaffolding proteins at cell junctions, are substrates of different proteases during apoptosis. | Cell death & disease 20110101 |
| Amyloid precursor protein binding protein Fe65 is cleaved by caspases during DNA damage-induced apoptosis. | Biological & pharmaceutical bulletin 20110101 |
| Gene-specific differential response to anti-apoptotic therapies in zebrafish models of ocular coloboma. | Molecular vision 20110101 |
| Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
| High-mobility group box-1 protein and keratin-18, circulating serum proteins informative of acetaminophen-induced necrosis and apoptosis in vivo. | Toxicological sciences : an official journal of the Society of Toxicology 20091201 |
| Oligomerized tumor necrosis factor-related apoptosis inducing ligand strongly induces cell death in myeloma cells, but also activates proinflammatory signaling pathways. | The FEBS journal 20091201 |
| Turnover of newborn olfactory bulb neurons optimizes olfaction. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090930 |
| Involvement of the p53 tumor-suppressor protein in the development of antinociceptive tolerance to morphine. | Neuroscience letters 20090206 |
| Sensitization by 5-azacytidine toward death receptor-induced hepatic apoptosis. | The Journal of pharmacology and experimental therapeutics 20090101 |
| Programmed necrotic cell death induced by complement involves a Bid-dependent pathway. | Journal of immunology (Baltimore, Md. : 1950) 20090101 |
| Dihydrocapsaicin (DHC), a saturated structural analog of capsaicin, induces autophagy in human cancer cells in a catalase-regulated manner. | Autophagy 20081101 |
| Cysteine cathepsins trigger caspase-dependent cell death through cleavage of bid and antiapoptotic Bcl-2 homologues. | The Journal of biological chemistry 20080704 |
| A Cdc7 kinase inhibitor restricts initiation of DNA replication and has antitumor activity. | Nature chemical biology 20080601 |
| Identification of RIP1 kinase as a specific cellular target of necrostatins. | Nature chemical biology 20080501 |
| Caspase inhibitor facilitates recovery of hearing by protecting the cochlear lateral wall from acute cochlear mitochondrial dysfunction. | Journal of neuroscience research 20080101 |
| Caspase inhibition reduces lymphocyte apoptosis and improves host immune responses to Trypanosoma cruzi infection. | European journal of immunology 20070301 |
| A calpain-like protease inhibits autophagic cell death. | Autophagy 20070101 |
| zVAD-fmk, unlike BocD-fmk, does not inhibit caspase-6 acting on 14-3-3/Bad pathway in apoptosis of p815 mastocytoma cells. | Experimental & molecular medicine 20061231 |
| Caspase activation contributes to endotoxin-induced diaphragm weakness. | Journal of applied physiology (Bethesda, Md. : 1985) 20060601 |
| Cancer cell mitochondria are direct proapoptotic targets for the marine antitumor drug lamellarin D. | Cancer research 20060315 |
| Blocking caspase activity prevents transsynaptic neuronal apoptosis and the loss of inhibition in lamina II of the dorsal horn after peripheral nerve injury. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20050810 |
| Preferential cell death of CD8+ effector memory (CCR7-CD45RA-) T cells by hydrogen peroxide-induced oxidative stress. | Journal of immunology (Baltimore, Md. : 1950) 20050515 |
| Phenoxodiol, a novel isoflavone, induces G1 arrest by specific loss in cyclin-dependent kinase 2 activity by p53-independent induction of p21WAF1/CIP1. | Cancer research 20050415 |
| Sensitization of stefin B-deficient thymocytes towards staurosporin-induced apoptosis is independent of cysteine cathepsins. | FEBS letters 20050411 |
| Acetoxycycloheximide (E-73) rapidly induces apoptosis mediated by the release of cytochrome c via activation of c-Jun N-terminal kinase. | Biochemical pharmacology 20050215 |
| Inhibition of malignant glioma cell growth by a survivin mutant retrovirus. | Human gene therapy 20050201 |
| Human cytomegalovirus proteins encoded by UL37 exon 1 protect infected fibroblasts against virus-induced apoptosis and are required for efficient virus replication. | The Journal of general virology 20041201 |
| Using a small molecule inhibitor of peptide: N-glycanase to probe its role in glycoprotein turnover. | Chemistry & biology 20041201 |
| Caspase inhibition protects against reovirus-induced myocardial injury in vitro and in vivo. | Journal of virology 20041001 |
| p38 MAPK mediates TNF-induced apoptosis in endothelial cells via phosphorylation and downregulation of Bcl-x(L). | Experimental cell research 20040815 |
| Effects of chloride and potassium channel blockers on apoptotic cell shrinkage and apoptosis in cortical neurons. | Pflugers Archiv : European journal of physiology 20040601 |
| Essential role of caspases in epigallocatechin-3-gallate-mediated inhibition of nuclear factor kappa B and induction of apoptosis. | Oncogene 20040401 |
| N-terminal fragment of c-FLIP(L) processed by caspase 8 specifically interacts with TRAF2 and induces activation of the NF-kappaB signaling pathway. | Molecular and cellular biology 20040401 |
| Overexpression of phospholipase D prevents actinomycin D-induced apoptosis through potentiation of phosphoinositide 3-kinase signalling pathways in Chinese-hamster ovary cells. | The Biochemical journal 20040301 |
| Antirestenotic effects of a locally delivered caspase inhibitor in a balloon injury model. | Circulation 20040106 |
| Cephalostatin 1 selectively triggers the release of Smac/DIABLO and subsequent apoptosis that is characterized by an increased density of the mitochondrial matrix. | Cancer research 20031215 |
| Involvement of Akt in mitochondria-dependent apoptosis induced by a cdc25 phosphatase inhibitor naphthoquinone analog. | FEBS letters 20031204 |
| Possible role of interleukin-6 in PC12 cell death induced by MPP+ and tetrahydroisoquinoline. | Journal of pharmacological sciences 20031201 |
| Lack of a functional p21WAF1/CIP1 gene accelerates caspase-independent apoptosis induced by cisplatin in renal cells. | American journal of physiology. Renal physiology 20030901 |
| Involvement of oxidative stress in apoptosis induced by a mixture of isothiazolinones in normal human keratinocytes. | The Journal of investigative dermatology 20030801 |
| Antioxidant dietary deficiency induces caspase activation in chick skeletal muscle cells. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20030801 |
| Caspase inhibitors promote vestibular hair cell survival and function after aminoglycoside treatment in vivo. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20030709 |
| Paraoxon induces apoptosis in EL4 cells via activation of mitochondrial pathways. | Toxicology and applied pharmacology 20030701 |
| Caspase-dependent cell death mediates the early phase of aortic hypertrophy regression in losartan-treated spontaneously hypertensive rats. | Circulation research 20030418 |
| Mitochondrial membrane permeabilization and superoxide production during apoptosis. A single-cell analysis. | The Journal of biological chemistry 20030411 |
| Slight impairment of Na+,K+-ATPase synergistically aggravates ceramide- and beta-amyloid-induced apoptosis in cortical neurons. | Brain research 20021115 |
| Caspase-independent phosphatidylserine exposure during apoptosis of primary T lymphocytes. | Journal of immunology (Baltimore, Md. : 1950) 20021101 |
| Grape seed extract induces apoptotic death of human prostate carcinoma DU145 cells via caspases activation accompanied by dissipation of mitochondrial membrane potential and cytochrome c release. | Carcinogenesis 20021101 |
| An ex vivo murine model to study poliovirus-induced apoptosis in nerve cells. | The Journal of general virology 20020801 |
| Mitochondrial voltage-dependent anion channel is involved in dopamine-induced apoptosis. | Journal of neurochemistry 20020701 |
| Cyclosporine A protects against arachidonic acid toxicity in rat hepatocytes: role of CYP2E1 and mitochondria. | Hepatology (Baltimore, Md.) 20020601 |
| Insulin-like growth factor binding protein-related protein 1 inhibits proliferation of MCF-7 breast cancer cells via a senescence-like mechanism. | Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 20020501 |
| Ionic mechanism of ouabain-induced concurrent apoptosis and necrosis in individual cultured cortical neurons. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020215 |
| Higher pH promotes megakaryocytic maturation and apoptosis. | Stem cells (Dayton, Ohio) 20020101 |
| 15-deoxy-Delta 12,14-prostaglandin J2 induces apoptosis of human hepatic myofibroblasts. A pathway involving oxidative stress independently of peroxisome-proliferator-activated receptors. | The Journal of biological chemistry 20011012 |
| Mechanism of apoptosis in HL-60 cells induced by n-3 and n-6 polyunsaturated fatty acids. | Biochemical pharmacology 20011001 |
| Caspase-dependent and serine protease-dependent DNA fragmentation of myocytes in the ischemia-reperfused rabbit heart: these inhibitors do not reduce infarct size. | Japanese circulation journal 20011001 |
| Survivin inhibition induces human neural tumor cell death through caspase-independent and -dependent pathways. | Journal of neurochemistry 20011001 |
| Helenalin triggers a CD95 death receptor-independent apoptosis that is not affected by overexpression of Bcl-x(L) or Bcl-2. | Cancer research 20010801 |
| Death receptor-induced apoptotic and necrotic cell death: differential role of caspases and mitochondria. | Cell death and differentiation 20010801 |
| Caspase-resistant vimentin suppresses apoptosis after photodynamic treatment with a silicon phthalocyanine in Jurkat cells. | Archives of biochemistry and biophysics 20010601 |
| Apoptosis and chemokine induction after renal ischemia-reperfusion. | Transplantation 20010415 |
| Possible changes in expression of chemotaxin LECT2 mRNA in mouse liver after concanavalin A-induced hepatic injury. | Biological & pharmaceutical bulletin 20010401 |
| A novel response of cancer cells to radiation involves autophagy and formation of acidic vesicles. | Cancer research 20010115 |
| Role of K(+) efflux in apoptosis induced by AMPA and kainate in mouse cortical neurons. | Neuroscience 20010101 |
| Structure/Function analysis of p55 tumor necrosis factor receptor and fas-associated death domain. Effect on necrosis in L929sA cells. | The Journal of biological chemistry 20001201 |
| Bisphosphonates induce breast cancer cell death in vitro. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20001101 |
| Suicidal differential housekeeping gene activity in apoptosis induced by DCNP. | Apoptosis : an international journal on programmed cell death 20001001 |
| Mechanisms to prevent the toxicity of chronic neuroinflammation on forebrain cholinergic neurons. | European journal of pharmacology 20000818 |
| Studies on the mechanism of the inhibition of human leukaemia cell growth by dietary isothiocyanates and their cysteine adducts in vitro. | Biochemical pharmacology 20000715 |
| E1A overcomes the apoptosis block in BCR-ABL+ leukemia cells and renders cells susceptible to induction of apoptosis by chemotherapeutic agents. | Cancer research 20000715 |
| A monoclonal antibody to amyloid precursor protein induces neuronal apoptosis. | Journal of neurochemistry 20000601 |
| The involvement of caspases in the CD95(Fas/Apo-1)- but not swelling-induced cellular taurine release from Jurkat T-lymphocytes. | Pflugers Archiv : European journal of physiology 20000501 |
| Molecular determinants of apoptosis induced by the cytotoxic ribonuclease onconase: evidence for cytotoxic mechanisms different from inhibition of protein synthesis. | Cancer research 20000401 |
| Prevention of lymphocyte cell death in sepsis improves survival in mice. | Proceedings of the National Academy of Sciences of the United States of America 19991207 |
| Human papillomavirus type 16 E6-enhanced susceptibility of L929 cells to tumor necrosis factor alpha correlates with increased accumulation of reactive oxygen species. | The Journal of biological chemistry 19990827 |
| Caspase inhibition in camptothecin-treated U-937 cells is coupled with a shift from apoptosis to transient G1 arrest followed by necrotic cell death. | Cancer research 19990801 |
| Geranylgeranylacetone induces apoptosis in HL-60 cells. | Cell structure and function 19990601 |
| Signaling pathway activated during apoptosis of the prostate cancer cell line LNCaP: overexpression of caspase-7 as a new gene therapy strategy for prostate cancer. | Cancer research 19990115 |
| Investigation of glucocorticoid-induced apoptotic pathway: processing of caspase-6 but not caspase-3. | Cell death and differentiation 19981201 |
| Caspase-independent cell death induced by anti-CD2 or staurosporine in activated human peripheral T lymphocytes. | Journal of immunology (Baltimore, Md. : 1950) 19981001 |
| Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways. | The Journal of experimental medicine 19980907 |
| Distinct steps in DNA fragmentation pathway during camptothecin-induced apoptosis involved caspase-, benzyloxycarbonyl- and N-tosyl-L-phenylalanylchloromethyl ketone-sensitive activities. | Cancer research 19980715 |
| Death of tumor cells after intracellular acidification is dependent on stress-activated protein kinases (SAPK/JNK) pathway activation and cannot be inhibited by Bcl-2 expression or interleukin 1beta-converting enzyme inhibition. | Cancer research 19980701 |
| Proteasome activities decrease during dexamethasone-induced apoptosis of thymocytes. | The Biochemical journal 19980601 |
| Attenuation of ischemia/reperfusion injury in rats by a caspase inhibitor. | Circulation 19980127 |
| Activation of PKCalpha downstream from caspases during apoptosis induced by 7-hydroxystaurosporine or the topoisomerase inhibitors, camptothecin and etoposide, in human myeloid leukemia HL60 cells. | The Journal of biological chemistry 19971212 |
| Different interleukin-1 beta converting enzyme (ICE) family protease requirements for the apoptotic death of T lymphocytes triggered by diverse stimuli. | The Journal of experimental medicine 19961201 |