N-[(Z)-(6-bromoimidazo[1,2-a]pyridin-3-yl)methylideneamino]-N,2-dimethyl-5-nitrobenzenesulfonamide
| Title | Journal |
|---|---|
| PI3K p110α/Akt signaling negatively regulates secretion of the intestinal peptide neurotensin through interference of granule transport. | Molecular endocrinology (Baltimore, Md.) 20120801 |
| Definition of the binding mode of a new class of phosphoinositide 3-kinase α-selective inhibitors using in vitro mutagenesis of non-conserved amino acids and kinetic analysis. | The Biochemical journal 20120615 |
| Suppression of PDGF-induced PI3 kinase activity by imatinib promotes adipogenesis and adiponectin secretion. | Journal of molecular endocrinology 20120601 |
| Characterization of molecular recognition of phosphoinositide-3-kinase α inhibitor through molecular dynamics simulation. | Journal of molecular modeling 20120501 |
| Effects of acutely inhibiting PI3K isoforms and mTOR on regulation of glucose metabolism in vivo. | The Biochemical journal 20120215 |
| Phosphoinositide 3-kinase signaling is critical for ErbB3-driven breast cancer cell motility and metastasis. | Oncogene 20120209 |
| Isoform-selective inhibition of phosphoinositide 3-kinase: identification of a new region of nonconserved amino acids critical for p110α inhibition. | Molecular pharmacology 20111001 |
| Phosphatidylinositol 3-kinase isoform-specific effects in airway mesenchymal cell function. | The Journal of pharmacology and experimental therapeutics 20110501 |
| Synthesis and biological evaluation of sulfonylhydrazone-substituted imidazo[1,2-a]pyridines as novel PI3 kinase p110alpha inhibitors. | Bioorganic & medicinal chemistry 20070901 |
| A pharmacological map of the PI3-K family defines a role for p110alpha in insulin signaling. | Cell 20060519 |