Temocapril HCl
| Title | Journal |
|---|---|
| Evaluation of transport mechanism of prodrugs and parent drugs formed by intracellular metabolism in Caco-2 cells with modified carboxylesterase activity: temocapril as a model case. | Journal of pharmaceutical sciences 20110901 |
| Prediction of human intestinal absorption of the prodrug temocapril by in situ single-pass perfusion using rat intestine with modified hydrolase activity. | Drug metabolism and disposition: the biological fate of chemicals 20110701 |
| [A ten-year follow-up of a 109-year-old woman with myocardial infarction]. | Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 20110101 |
| [Role of angiontensin receptors in remodeling perivascular nerves]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20101101 |
| The effect of angiotensin-converting enzyme inhibitors of left atrial pressure in dogs with mitral valve regurgitation. | Journal of veterinary internal medicine 20100101 |
| Effect of angiotensin-converting enzyme inhibitor on serum asymmetric dimethylarginine and coronary circulation in patients with type 2 diabetes mellitus. | International journal of cardiology 20090220 |
| Olmesartan and temocapril prevented the development of hyperglycemia and the deterioration of pancreatic islet morphology in Otsuka-Long-Evans-Tokushima Fatty rats. | Acta medica Okayama 20090201 |
| In half of hypertensive diabetics, co-administration of a calcium channel blocker and an angiotensin-converting enzyme inhibitor achieved a target blood pressure of <130/80 mmHg: the azelnidipine and temocapril in hypertensive patients with type 2 diabetes (ATTEST) study. | Hypertension research : official journal of the Japanese Society of Hypertension 20080801 |
| Beneficial effects of olmesartan and temocapril on urinary liver-type fatty acid-binding protein levels in normotensive patients with immunoglobin A nephropathy. | American journal of hypertension 20071101 |
| Effects of monotherapy of temocapril or candesartan with dose increments or combination therapy with both drugs on the suppression of diabetic nephropathy. | Hypertension research : official journal of the Japanese Society of Hypertension 20070401 |
| Aldosterone breakthrough during therapy with angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers in proteinuric patients with immunoglobulin A nephropathy. | Nephrology (Carlton, Vic.) 20061001 |
| Angiotensin I-converting enzyme inhibitor improves reactive hyperemia in elderly hypertensives with arteriosclerosis obliterans. | Hypertension research : official journal of the Japanese Society of Hypertension 20060901 |
| Nephrotic syndrome and IgA nephropathy in polycystic kidney disease. | Clinical and experimental nephrology 20060601 |
| Effects of organic anion transporting polypeptide 1B1 haplotype on pharmacokinetics of pravastatin, valsartan, and temocapril. | Clinical pharmacology and therapeutics 20060501 |
| Effect on coronary flow velocity reserve in patients with type 2 diabetes mellitus: comparison between angiotensin-converting enzyme inhibitor and angiotensin II type 1 receptor antagonist. | American heart journal 20060401 |
| Angiotensin converting enzyme inhibitor attenuates oxidative stress-induced endothelial cell apoptosis via p38 MAP kinase inhibition. | Clinica chimica acta; international journal of clinical chemistry 20060201 |
| Identification of esterases expressed in Caco-2 cells and effects of their hydrolyzing activity in predicting human intestinal absorption. | Drug metabolism and disposition: the biological fate of chemicals 20050801 |
| Renin-angiotensin system modulates oxidative stress-induced endothelial cell apoptosis in rats. | Hypertension (Dallas, Tex. : 1979) 20050601 |
| Dual ECE/NEP inhibition on cardiac and neurohumoral function during the transition from hypertrophy to heart failure in rats. | Hypertension (Dallas, Tex. : 1979) 20050601 |
| Angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers effectively and directly potentiate superoxide scavenging by polymorphonuclear leukocytes from patients with type 2 diabetes mellitus. | The American journal of the medical sciences 20050501 |
| Long-term inhibition of angiotensin prevents reduction of periarterial innervation of calcitonin gene-related peptide (CGRP)-containing nerves in spontaneously hypertensive rats. | Hypertension research : official journal of the Japanese Society of Hypertension 20050501 |
| Endothelium-derived hydrogen peroxide accounts for the enhancing effect of an angiotensin-converting enzyme inhibitor on endothelium-derived hyperpolarizing factor-mediated responses in mice. | Arteriosclerosis, thrombosis, and vascular biology 20050401 |
| Different accumulation of temocapril and enalapril during repeated dosing in elderly patients. | British journal of clinical pharmacology 20050401 |
| Temporary angiotensin II blockade at the prediabetic stage attenuates the development of renal injury in type 2 diabetic rats. | Journal of the American Society of Nephrology : JASN 20050301 |
| Angiotensin-converting-enzyme inhibitors slow renal decline in IgA nephropathy, independent of tubulointerstitial fibrosis at presentation. | QJM : monthly journal of the Association of Physicians 20050301 |
| ACE inhibitor and angiotensin II type 1 receptor blocker differently regulate ventricular fibrosis in hypertensive diastolic heart failure. | Journal of hypertension 20050201 |
| Exercise-related syncope induced by vasodilator therapy in an elderly hypertensive patient. | Journal of the American Geriatrics Society 20050201 |
| Insulin sensitivity and endothelial function in hypertension: a comparison of temocapril and candesartan. | American journal of hypertension 20050201 |
| Renal artery stenosis emerged after angiotensin-converting enzyme inhibitor treatment for myocardial infarction: a case report. | Angiology 20050101 |
| Low-dose combination therapy with temocapril and losartan reduces proteinuria in normotensive patients with immunoglobulin a nephropathy. | Hypertension research : official journal of the Japanese Society of Hypertension 20041201 |
| Blockade of the renin-angiotensin system decreases adipocyte size with improvement in insulin sensitivity. | Journal of hypertension 20041001 |
| Additive beneficial effects of the combination of a calcium channel blocker and an angiotensin blocker on a hypertensive rat-heart failure model. | Hypertension research : official journal of the Japanese Society of Hypertension 20041001 |
| Asymmetric dimethylarginine produces vascular lesions in endothelial nitric oxide synthase-deficient mice: involvement of renin-angiotensin system and oxidative stress. | Arteriosclerosis, thrombosis, and vascular biology 20040901 |
| Salutary effects of attenuation of angiotensin II on coronary perivascular fibrosis associated with insulin resistance and obesity. | Journal of molecular and cellular cardiology 20040801 |
| Renoprotective effect of angiotensin-converting enzyme inhibitor combined with alpha1-adrenergic antagonist in spontaneously hypertensive rats with renal ablation. | Hypertension research : official journal of the Japanese Society of Hypertension 20040701 |
| AT1 receptor blocker added to ACE inhibitor provides benefits at advanced stage of hypertensive diastolic heart failure. | Hypertension (Dallas, Tex. : 1979) 20040301 |
| Regulation of skeletal muscle peroxisome proliferator-activated receptor gamma expression by exercise and angiotensin-converting enzyme inhibition in fructose-fed hypertensive rats. | Hypertension research : official journal of the Japanese Society of Hypertension 20040101 |
| Comparison of urinary excretion of pravastatin and temocapril in bile duct-ligated rats and Eisai hyperbilirubinemic rats (EHBR). | Journal of hepato-biliary-pancreatic surgery 20040101 |
| Pharmacological and clinical studies with temocapril, an angiotensin converting enzyme inhibitor that is excreted in the bile. | Cardiovascular drug reviews 20040101 |
| Effects of exercise training on glomerular structure in fructose-fed spontaneously hypertensive rats. | Hypertension research : official journal of the Japanese Society of Hypertension 20031101 |
| Successful treatment of severe hypertension with the combination of angiotensin converting enzyme inhibitor and angiotensin II receptor blocker. | Hypertension research : official journal of the Japanese Society of Hypertension 20031001 |
| A newly developed angiotensin II type 1 receptor antagonist, CS866, promotes regression of cardiac hypertrophy by reducing integrin beta1 expression. | Hypertension research : official journal of the Japanese Society of Hypertension 20030901 |
| Evaluation of systemic blood NO dynamics by EPR spectroscopy: HbNO as an endogenous index of NO. | American journal of physiology. Heart and circulatory physiology 20030801 |
| Human-derived vascular smooth muscle cells produce angiotensin II by changing to the synthetic phenotype. | Journal of cellular physiology 20030801 |
| Beneficial effects of angiotensin-converting enzyme inhibition on sarcoplasmic reticulum function in the failing heart of the Dahl rat. | Circulation journal : official journal of the Japanese Circulation Society 20030801 |
| Efficacy of various antihypertensive agents as evaluated by indices of vascular stiffness in elderly hypertensive patients. | Hypertension research : official journal of the Japanese Society of Hypertension 20030801 |
| Blockade of the renin-angiotensin system increases adiponectin concentrations in patients with essential hypertension. | Hypertension (Dallas, Tex. : 1979) 20030701 |
| Should increasing the dose or adding an AT1 receptor blocker follow a relatively low dose of ACE inhibitor initiated in acute myocardial infarction? | Cardiovascular research 20030601 |
| Temocapril treatment ameliorates autoimmune myocarditis associated with enhanced cardiomyocyte thioredoxin expression. | Molecular and cellular biochemistry 20030601 |
| [Temocapril treatment upregulated cardiomyocyte thioredoxin expression and improved autoimmune myocarditis]. | Zhonghua nei ke za zhi 20030501 |
| Temocapril prevents motor neuron damage and upregulation of cyclooxygenase-II in glutamate-induced neurotoxicity. | Neurological research 20030401 |
| Chronic angiotensin II inhibition increases levels of calcitonin gene-related peptide mRNA of the dorsal root ganglia in spontaneously hypertensive rats. | Hypertension research : official journal of the Japanese Society of Hypertension 20030301 |
| Effects of angiotensin-converting enzyme inhibition and angiotensin II type 1 receptor blockade on beta-adrenoceptor signaling in heart failure produced by myocardial Infarction in rabbits: reversal of altered expression of beta-adrenoceptor kinase and G i alpha. | The Journal of pharmacology and experimental therapeutics 20030101 |
| Beneficial effects of combination of ACE inhibitor and angiotensin II type 1 receptor blocker on cardiac remodeling in rat myocardial infarction. | Cardiovascular research 20030101 |
| Effects of temocapril and olmesartan on myocardial sympathetic nervous activity and fatty acid metabolism in rats with chronic beta-adrenergic stimulation. | Journal of cardiovascular pharmacology 20030101 |
| [Successful treatment of combination therapy using an angiotensin-converting enzyme inhibitor and an angiotensin II receptor blocker in a patient with IgA nephropathy]. | Nihon Jinzo Gakkai shi 20030101 |
| Antiproteinuric effects of combined antihypertensive therapies in patients with overt type 2 diabetic nephropathy. | Hypertension research : official journal of the Japanese Society of Hypertension 20021101 |
| Impact of exercise and angiotensin converting enzyme inhibition on tumor necrosis factor-alpha and leptin in fructose-fed hypertensive rats. | Hypertension research : official journal of the Japanese Society of Hypertension 20021101 |
| Chronic angiotensin-converting enzyme inhibition and angiotensin II antagonism in rats with chronic renal failure. | Journal of cardiovascular pharmacology 20021001 |
| An angiotensin-converting enzyme inhibitor, not an angiotensin II type-1 receptor blocker, prevents beta-aminopropionitrile monofumarate-induced aortic dissection in rats. | Journal of vascular surgery 20021001 |
| CS-886, a new angiotensin II type 1 receptor antagonist, ameliorates glomerular anionic site loss and prevents progression of diabetic nephropathy in Otsuka Long-Evans Tokushima fatty rats. | Molecular medicine (Cambridge, Mass.) 20021001 |
| ACE inhibitor improves insulin resistance in diabetic mouse via bradykinin and NO. | Hypertension (Dallas, Tex. : 1979) 20020901 |
| Inhibition of renin-angiotensin system ameliorates endothelial dysfunction associated with aging in rats. | Arteriosclerosis, thrombosis, and vascular biology 20020901 |
| [Effects of temocapril on the prevention of early diabetic nephropathy in OLETF rat, an animal model for type 2 diabetes]. | [Hokkaido igaku zasshi] The Hokkaido journal of medical science 20020901 |
| Beneficial effects of combined blockade of ACE and AT1 receptor on intimal hyperplasia in balloon-injured rat artery. | Arteriosclerosis, thrombosis, and vascular biology 20020801 |
| Combination therapy of exercise and angiotensin-converting enzyme inhibitor markedly improves insulin sensitivities in hypertensive patients with insulin resistance. | Circulation journal : official journal of the Japanese Circulation Society 20020701 |
| Differential effects of a long-acting angiotensin converting enzyme inhibitor (temocapril) and a long-acting calcium antagonist (amlodipine) on ventricular ectopic beats in older hypertensive patients. | Hypertension research : official journal of the Japanese Society of Hypertension 20020501 |
| Combination therapy with an angiotensin-converting enzyme (ACE) inhibitor and a calcium antagonist: beyond the renoprotective effects of ACE inhibitor monotherapy in a spontaneous hypertensive rat with renal ablation. | Hypertension research : official journal of the Japanese Society of Hypertension 20020501 |
| Combined effect of ACE inhibitor and exercise training on insulin resistance in type 2 diabetic rats. | Life sciences 20020301 |
| Inhibitory effect of a novel angiotensin II type 1 receptor antagonist RNH-6270 on growth of vascular smooth muscle cells from spontaneously hypertensive rats: different anti-proliferative effect to angiotensin-converting enzyme inhibitor. | Journal of cardiovascular pharmacology 20020201 |
| Temocapril, a long-acting non-SH group angiotensin converting enzyme inhibitor, modulates glomerular injury in chronic puromycin aminonucleoside nephrosis. | Journal of nephrology 20020101 |
| [Effects of CS-866, an angiotensin II receptor antagonist, in 5/6 nephrectomized spontaneously hypertensive rats]. | Nihon Jinzo Gakkai shi 20011001 |
| Effects of long-acting ACE inhibitor (temocapril) and long-acting Ca channel blocker (amlodipine) on 24-h ambulatory BP in elderly hypertensive patients. | Journal of human hypertension 20010901 |
| Differential subcellular actions of ACE inhibitors and AT(1) receptor antagonists on cardiac remodeling induced by chronic inhibition of NO synthesis in rats. | Hypertension (Dallas, Tex. : 1979) 20010901 |
| Differential effects of angiotensin II versus endothelin-1 inhibitions in hypertrophic left ventricular myocardium during transition to heart failure. | Circulation 20010731 |
| Angiotensin-converting enzyme inhibition attenuates hypofibrinolysis and reduces cardiac perivascular fibrosis in genetically obese diabetic mice. | Circulation 20010626 |
| Angiotensin blockade inhibits increased JNKs, AP-1 and NF- kappa B DNA-binding activities in myocardial infarcted rats. | Journal of molecular and cellular cardiology 20010401 |
| Effects of troglitazone and temocapril in spontaneously hypertensive rats with chronic renal failure. | Journal of hypertension 20010301 |
| Effect of temocapril hydrochloride on serum lipid levels in patients with hypertensive type 2 diabetes mellitus. | Journal of atherosclerosis and thrombosis 20010101 |
| Prevention of doxorubicin (adriamycin)-induced cardiomyopathy by simultaneous administration of angiotensin-converting enzyme inhibitor assessed by acoustic densitometry. | Journal of cardiovascular pharmacology 20000901 |
| Hydrolytic profile for ester- or amide-linkage by carboxylesterases pI 5.3 and 4.5 from human liver. | Biological & pharmaceutical bulletin 19970801 |
| Pharmacokinetics of temocapril, an ACE inhibitor with preferential biliary excretion, in patients with impaired liver function. | European journal of clinical pharmacology 19930101 |
| Pharmacokinetics of temocapril hydrochloride, a novel angiotensin converting enzyme inhibitor, in renal insufficiency. | European journal of clinical pharmacology 19920101 |