Benzeneethanol,b-[[4-[2-(dimethylamino)ethoxy]phenyl]phenylmethylene]-a-methyl-,(bE)-
| Title | Journal |
|---|---|
| Assessment of the impact of CYP3A polymorphisms on the formation of α-hydroxytamoxifen and N-desmethyltamoxifen in human liver microsomes. | Drug metabolism and disposition: the biological fate of chemicals 20120201 |
| Effect of N,N-didesmethyltamoxifen upon DNA adduct formation by tamoxifen and alpha-hydroxytamoxifen. | Cancer letters 20071118 |
| Formation of tamoxifen-DNA adducts via O-sulfonation, not O-acetylation, of alpha-hydroxytamoxifen in rat and human livers. | Drug metabolism and disposition: the biological fate of chemicals 20051101 |
| Tamoxifen-DNA adduct formation in human endometrium. | Chemical research in toxicology 20051001 |
| Characterization of the human cytochrome P450 forms involved in metabolism of tamoxifen to its alpha-hydroxy and alpha,4-dihydroxy derivatives. | Chemical research in toxicology 20051001 |
| Organ specificity of DNA adduct formation by tamoxifen and alpha-hydroxytamoxifen in the rat: implications for understanding the mechanism(s) of tamoxifen carcinogenicity and for human risk assessment. | Mutagenesis 20050701 |
| Formation of tamoxifen-DNA adducts in human endometrial explants exposed to alpha-hydroxytamoxifen. | Chemical research in toxicology 20050501 |
| UDP-glucuronosyltransferases and clinical drug-drug interactions. | Pharmacology & therapeutics 20050401 |
| Interactions of the stereoisomers of alpha-hydroxytamoxifen with human hydroxysteroid sulfotransferase SULT2A1 and rat hydroxysteroid sulfotransferase STa. | Drug metabolism and disposition: the biological fate of chemicals 20041201 |
| Stereoselective metabolic activation of alpha-hydroxy-N-desmethyltamoxifen: the R-isomer forms more DNA adducts in rat liver cells. | Chemical research in toxicology 20040501 |
| Biotransformation of tamoxifen in a human endometrial explant culture model. | Chemico-biological interactions 20031215 |
| Alpha-hydroxylation of tamoxifen and toremifene by human and rat cytochrome P450 3A subfamily enzymes. | Chemical research in toxicology 20030901 |
| Identification of human CYP forms involved in the activation of tamoxifen and irreversible binding to DNA. | Carcinogenesis 20021101 |
| The mutational signature of alpha-hydroxytamoxifen at Hprt locus in Chinese hamster cells. | Carcinogenesis 20021101 |
| Mutations induced by alpha-hydroxytamoxifen in the lacI and cII genes of Big Blue transgenic rats. | Carcinogenesis 20021001 |
| Induction of lacI mutations in Big Blue rats treated with tamoxifen and alpha-hydroxytamoxifen. | Cancer letters 20020208 |
| Resolution of alpha-hydroxytamoxifen; R-isomer forms more DNA adducts in rat liver cells. | Chemical research in toxicology 20010701 |
| Short-term dosing of alpha-hydroxytamoxifen results in DNA damage but does not lead to liver tumours in female Wistar/Han rats. | Carcinogenesis 20010401 |