4-((7-Chloroquinolin-4-yl)amino)-2-((diethylamino)methyl)phenol
| Title | Journal |
|---|---|
| The Effects of Immune Modulators on Amodiaquine-Induced Liver Injury. | Chemical research in toxicology 20180820 |
| New therapeutic approaches and novel alternatives for organophosphate toxicity. | Toxicology letters 20180701 |
| Reduction and Scavenging of Chemically Reactive Drug Metabolites by NAD(P)H:Quinone Oxidoreductase 1 and NRH:Quinone Oxidoreductase 2 and Variability in Hepatic Concentrations. | Chemical research in toxicology 20180219 |
| Human glutathione S-transferases- and NAD(P)H:quinone oxidoreductase 1-catalyzed inactivation of reactive quinoneimines of amodiaquine and N-desethylamodiaquine: Possible implications for susceptibility to amodiaquine-induced liver toxicity. | Toxicology letters 20170605 |
| The effect of milk thistle (Silybum marianum) and its main flavonolignans on CYP2C8 enzyme activity in human liver microsomes. | Chemico-biological interactions 20170601 |
| In vitro toxicological evaluation of NCS-382, a high-affinity antagonist of γ-hydroxybutyrate (GHB) binding. | Toxicology in vitro : an international journal published in association with BIBRA 20170401 |
| High content analysis assay for prediction of human hepatotoxicity in HepaRG and HepG2 cells. | Toxicology in vitro : an international journal published in association with BIBRA 20160601 |
| Cytochrome P450 inhibition potential of new psychoactive substances of the tryptamine class. | Toxicology letters 20160122 |
| Antimalarial benzoheterocyclic 4-aminoquinolines: Structure-activity relationship, in vivo evaluation, mechanistic and bioactivation studies. | Bioorganic & medicinal chemistry 20150901 |
| Involvement of myeloperoxidase and NADPH oxidase in the covalent binding of amodiaquine and clozapine to neutrophils: implications for drug-induced agranulocytosis. | Chemical research in toxicology 20140421 |
| In vivo antimalarial evaluation of MAMA decoction on Plasmodium berghei in mice. | Parasitology research 20140201 |
| A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans. | Toxicological sciences : an official journal of the Society of Toxicology 20140101 |
| The antimalarial amodiaquine causes autophagic-lysosomal and proliferative blockade sensitizing human melanoma cells to starvation- and chemotherapy-induced cell death. | Autophagy 20131201 |
| Tetrazole-based deoxyamodiaquines: synthesis, ADME/PK profiling and pharmacological evaluation as potential antimalarial agents. | Bioorganic & medicinal chemistry 20130901 |
| The inhibition of major human hepatic cytochrome P450 enzymes by 18 pesticides: comparison of the N-in-one and single substrate approaches. | Toxicology in vitro : an international journal published in association with BIBRA 20130801 |
| Ex vivo responses of Plasmodium falciparum clinical isolates to conventional and new antimalarial drugs in Niger. | Antimicrobial agents and chemotherapy 20130701 |
| Quinolone-3-diarylethers: a new class of antimalarial drug. | Science translational medicine 20130320 |
| Identification of inhibitors of Plasmodium falciparum gametocyte development. | Malaria journal 20130101 |
| A SYBR Green 1-based in vitro test of susceptibility of Ghanaian Plasmodium falciparum clinical isolates to a panel of anti-malarial drugs. | Malaria journal 20130101 |
| Mimicking the intramolecular hydrogen bond: synthesis, biological evaluation, and molecular modeling of benzoxazines and quinazolines as potential antimalarial agents. | Journal of medicinal chemistry 20121213 |
| Biowaiver monographs for immediate release solid oral dosage forms: amodiaquine hydrochloride. | Journal of pharmaceutical sciences 20121201 |
| Assessment of the molecular marker of Plasmodium falciparum chloroquine resistance (Pfcrt) in Senegal after several years of chloroquine withdrawal. | The American journal of tropical medicine and hygiene 20121003 |
| Evolution of the pfcrt T76 and pfmdr1 Y86 markers and chloroquine susceptibility 8 years after cessation of chloroquine use in Pikine, Senegal. | Parasitology research 20121001 |
| A simple dose regimen of artesunate and amodiaquine based on arm span- or age range for childhood falciparum malaria: a preliminary evaluation. | Journal of tropical pediatrics 20120801 |
| Investigation of the interaction between amodiaquine and human serum albumin by fluorescence spectroscopy and molecular modeling. | European journal of medicinal chemistry 20120801 |
| Benzoheterocyclic amodiaquine analogues with potent antiplasmodial activity: synthesis and pharmacological evaluation. | Bioorganic & medicinal chemistry letters 20120801 |
| Crystal structure of phosphoethanolamine methyltransferase from Plasmodium falciparum in complex with amodiaquine. | Bioorganic & medicinal chemistry letters 20120801 |
| Artesunate- and amodiaquine-associated extrapyramidal reactions: a series of 49 cases in VigiBase™. | Drug safety 20120801 |
| An analytical method for assessing stage-specific drug activity in Plasmodium vivax malaria: implications for ex vivo drug susceptibility testing. | PLoS neglected tropical diseases 20120801 |
| Confirmation of Frm2 as a novel nitroreductase in Saccharomyces cerevisiae. | Biochemical and biophysical research communications 20120713 |
| New trifluoromethyl triazolopyrimidines as anti-Plasmodium falciparum agents. | Molecules (Basel, Switzerland) 20120710 |
| A simple dose regimen of artesunate and amodiaquine based on age or body weight range for uncomplicated falciparum malaria in children: comparison of therapeutic efficacy with standard dose regimen of artesunate and amodiaquine and artemether-lumefantrine. | American journal of therapeutics 20120701 |
| Repeated artemisinin-based combination therapies in a malaria hyperendemic area of Mali: efficacy, safety, and public health impact. | The American journal of tropical medicine and hygiene 20120701 |
| Potential P-glycoprotein-mediated drug-drug interactions of antimalarial agents in Caco-2 cells. | The American journal of tropical medicine and hygiene 20120701 |
| Antimalarial efficacy of a quantified extract of Nauclea pobeguinii stem bark in human adult volunteers with diagnosed uncomplicated falciparum malaria. Part 2: a clinical phase IIB trial. | Planta medica 20120601 |
| Development of a generic micellar electrokinetic chromatography method for the separation of 15 antimalarial drugs as a tool to detect medicine counterfeiting. | Electrophoresis 20120601 |
| Efficacy of different primaquine-based antimalarial regimens against Plasmodium falciparum gametocytemia. | Acta tropica 20120501 |
| Identifying a selective substrate and inhibitor pair for the evaluation of CYP2J2 activity. | Drug metabolism and disposition: the biological fate of chemicals 20120501 |
| A case of imported Plasmodium malariae malaria. | Annals of laboratory medicine 20120501 |
| 7-Chloro-4-(piperazin-1-yl)quinoline. | Acta crystallographica. Section E, Structure reports online 20120501 |
| 4,7-Dichloro-quinoline. | Acta crystallographica. Section E, Structure reports online 20120501 |
| Gene, ethnic and gender influences predisposition of adverse drug reactions to artesunate among Malaysians. | Toxicology mechanisms and methods 20120401 |
| Selective inhibitors of protozoan protein N-myristoyltransferases as starting points for tropical disease medicinal chemistry programs. | PLoS neglected tropical diseases 20120401 |
| In vitro assessment of drug resistance in Plasmodium falciparum in five States of India. | The Indian journal of medical research 20120401 |
| A modified serial blood sampling technique and utility of dried-blood spot technique in estimation of blood concentration: application in mouse pharmacokinetics. | European journal of drug metabolism and pharmacokinetics 20120301 |
| Drug-drug interaction analysis of pyronaridine/artesunate and ritonavir in healthy volunteers. | The American journal of tropical medicine and hygiene 20120301 |
| Intermittent preventive treatment for malaria in Papua New Guinean infants exposed to Plasmodium falciparum and P. vivax: a randomized controlled trial. | PLoS medicine 20120301 |
| Intermittent preventive treatment for malaria in children living in areas with seasonal transmission. | The Cochrane database of systematic reviews 20120215 |
| Compliance, safety, and effectiveness of fixed-dose artesunate-amodiaquine for presumptive treatment of non-severe malaria in the context of home management of malaria in Madagascar. | The American journal of tropical medicine and hygiene 20120201 |
| Different patterns of pfcrt and pfmdr1 polymorphisms in P. falciparum isolates from Nigeria and Brazil: the potential role of antimalarial drug selection pressure. | The American journal of tropical medicine and hygiene 20120201 |
| A ferrocene-based reagent for the conjugation and quantification of reactive metabolites. | Analytical and bioanalytical chemistry 20120101 |
| Antitumor activity of artemisinin and its derivatives: from a well-known antimalarial agent to a potential anticancer drug. | Journal of biomedicine & biotechnology 20120101 |
| Clindamycin plus quinine for treating uncomplicated falciparum malaria: a systematic review and meta-analysis. | Malaria journal 20120101 |
| Mutant pfcrt 'SVMNT' haplotype and wild type pfmdr1 'N86' are endemic in Plasmodium vivax dominated areas of India under high chloroquine exposure. | Malaria journal 20120101 |
| Development of a TaqMan Allelic Discrimination assay for detection of single nucleotides polymorphisms associated with anti-malarial drug resistance. | Malaria journal 20120101 |
| Diversity of Plasmodium falciparum chloroquine resistance transporter (pfcrt) exon 2 haplotypes in the Pacific from 1959 to 1979. | PloS one 20120101 |
| Comparing changes in haematologic parameters occurring in patients included in randomized controlled trials of artesunate-amodiaquine vs single and combination treatments of uncomplicated falciparum in sub-Saharan Africa. | Malaria journal 20120101 |
| Defining Plasmodium falciparum treatment in South West Asia: a randomized trial comparing artesunate or primaquine combined with chloroquine or SP. | PloS one 20120101 |
| Medicinal plants used by various tribes of bangladesh for treatment of malaria. | Malaria research and treatment 20120101 |
| Combination of probenecid-sulphadoxine-pyrimethamine for intermittent preventive treatment in pregnancy. | Malaria journal 20120101 |
| Feasibility of home management using ACT for childhood malaria episodes in an urban setting. | Drug, healthcare and patient safety 20120101 |
| Ex vivo activity of the ACT new components pyronaridine and piperaquine in comparison with conventional ACT drugs against isolates of Plasmodium falciparum. | Malaria journal 20120101 |
| Differential adhesive properties of sequestered asexual and sexual stages of Plasmodium falciparum on human endothelial cells are tissue independent. | PloS one 20120101 |
| Efficacy of artemether-lumefantrine in treatment of malaria among under-fives and prevalence of drug resistance markers in Igombe-Mwanza, north-western Tanzania. | Malaria journal 20120101 |
| A high performance liquid chromatographic assay of mefloquine in saliva after a single oral dose in healthy adult Africans. | Malaria journal 20120101 |
| Biological activities of nitidine, a potential anti-malarial lead compound. | Malaria journal 20120101 |
| The role of age and exposure to Plasmodium falciparum in the rate of acquisition of naturally acquired immunity: a randomized controlled trial. | PloS one 20120101 |
| Intermittent preventive treatment of malaria in children: a qualitative study of community perceptions and recommendations in Burkina Faso and Mali. | PloS one 20120101 |
| Genetic diversity and population structure of genes encoding vaccine candidate antigens of Plasmodium vivax. | Malaria journal 20120101 |
| Priority setting for the implementation of artemisinin-based combination therapy policy in Tanzania: evaluation against the accountability for reasonableness framework. | Implementation science : IS 20120101 |
| Management of uncomplicated malaria in febrile under five-year-old children by community health workers in Madagascar: reliability of malaria rapid diagnostic tests. | Malaria journal 20120101 |
| Artesunate-amodiaquine fixed dose combination for the treatment of Plasmodium falciparum malaria in India. | Malaria journal 20120101 |
| A histopathologic study of fatal paediatric cerebral malaria caused by mixed Plasmodium falciparum/Plasmodium vivax infections. | Malaria journal 20120101 |
| Relationship between treatment-seeking behaviour and artemisinin drug quality in Ghana. | Malaria journal 20120101 |
| Pfatp6 molecular profile of Plasmodium falciparum isolates in the western Brazilian Amazon. | Malaria journal 20120101 |
| Molecular monitoring of Plasmodium falciparum drug susceptibility at the time of the introduction of artemisinin-based combination therapy in Yaoundé, Cameroon: implications for the future. | Malaria journal 20120101 |
| Nevirapine-Based Antiretroviral Therapy Impacts Artesunate and Dihydroartemisinin Disposition in HIV-Infected Nigerian Adults. | AIDS research and treatment 20120101 |
| The frequency of malaria is similar among women receiving either lopinavir/ritonavir or nevirapine-based antiretroviral treatment. | PloS one 20120101 |
| Activity of clinically relevant antimalarial drugs on Plasmodium falciparum mature gametocytes in an ATP bioluminescence 'transmission blocking' assay. | PloS one 20120101 |
| Efficacy and Tolerability of Malartin and Sulphadoxine-Pyrimethamine Combination against Uncomplicated Falciparum Malaria in Dibanda, Southwest Cameroon. | Journal of tropical medicine 20120101 |
| Distribution of human CYP2C8*2 allele in three different African populations. | Malaria journal 20120101 |
| Effect of a New Prokinetic Agent DA-9701 Formulated with Corydalis Tuber and Pharbitidis Semen on Cytochrome P450 and UDP-Glucuronosyltransferase Enzyme Activities in Human Liver Microsomes. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
| Capillary electrophoresis for the assay of fixed-dose combination tablets of artesunate and amodiaquine. | Malaria journal 20120101 |
| Ready-to-use therapeutic food for catch-up growth in children after an episode of Plasmodium falciparum malaria: an open randomised controlled trial. | PloS one 20120101 |
| Therapeutic Efficacy of Artemether-Lumefantrine for the Treatment of Uncomplicated Plasmodium falciparum Malaria in Northern Ethiopia. | Malaria research and treatment 20120101 |
| Molecular modeling and evaluation of binding mode and affinity of artemisinin-quinine hybrid and its congeners with Fe-protoporphyrin-IX as a putative receptor. | Bioinformation 20120101 |
| Efficacy of ICON® Maxx in the laboratory and against insecticide-resistant Anopheles gambiae in central Côte d'Ivoire. | Malaria journal 20120101 |
| Efficacy of fixed-dose combination artesunate-amodiaquine versus artemether-lumefantrine for uncomplicated childhood Plasmodium falciparum malaria in Democratic Republic of Congo: a randomized non-inferiority trial. | Malaria journal 20120101 |
| Prevalence of molecular markers of Plasmodium falciparum drug resistance in Dakar, Senegal. | Malaria journal 20120101 |
| In vitro sensitivity of Plasmodium falciparum from China-Myanmar border area to major ACT drugs and polymorphisms in potential target genes. | PloS one 20120101 |
| Malaria and hiv in adults: when the parasite runs into the virus. | Mediterranean journal of hematology and infectious diseases 20120101 |
| The efficacy and tolerability of artemisinin-piperaquine (Artequick®) versus artesunate-amodiaquine (Coarsucam™) for the treatment of uncomplicated Plasmodium falciparum malaria in south-central Vietnam. | Malaria journal 20120101 |
| Hematoxicity of amodiaquine in sprague-dawley rats. | Toxicology international 20120101 |
| Decreased prevalence of Plasmodium falciparum resistance markers to amodiaquine despite its wide scale use as ACT partner drug in Zanzibar. | Malaria journal 20120101 |
| Enhanced screening of glutathione-trapped reactive metabolites by in-source collision-induced dissociation and extraction of product ion using UHPLC-high resolution mass spectrometry. | Analytical chemistry 20111215 |
| Malaria morbidity and pyrethroid resistance after the introduction of insecticide-treated bednets and artemisinin-based combination therapies: a longitudinal study. | The Lancet. Infectious diseases 20111201 |
| In vitro amodiaquine resistance and its association with mutations in pfcrt and pfmdr1 genes of Plasmodium falciparum isolates from Nigeria. | Acta tropica 20111201 |
| Malaria treatment and prophylaxis in endemic and nonendemic countries: evidence on strategies and their cost-effectiveness. | Future microbiology 20111201 |
| The use of artemether-lumefantrine for the treatment of uncomplicated Plasmodium vivax malaria. | PLoS neglected tropical diseases 20111201 |
| Effect of Inducers, Incubation Time and Heme Concentration on IC(50) Value Variation in Anti-heme Crystallization Assay. | Tropical medicine and health 20111201 |
| Dihydroartemisinin-piperaquine versus chloroquine in the treatment of Plasmodium vivax malaria in Thailand: a randomized controlled trial. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20111115 |
| Thermodynamic evaluation of ligand binding in the plant-like phosphoethanolamine methyltransferases of the parasitic nematode Haemonchus contortus. | The Journal of biological chemistry 20111104 |
| Are counterfeit or substandard anti-infective products the cause of treatment failure in Papua New Guinea? | Journal of pharmaceutical sciences 20111101 |
| Plasmodium falciparum: effect of antimalarial drugs, malaria pigment (β-haematin) and Plasmodium falciparum lysate on monocyte GTP-cyclohydrolase 1 gene expression. | Experimental parasitology 20111101 |
| Indolone-N-oxide derivatives: in vitro activity against fresh clinical isolates of Plasmodium falciparum, stage specificity and in vitro interactions with established antimalarial drugs. | The Journal of antimicrobial chemotherapy 20111101 |
| Genetic linkage analyses redefine the roles of PfCRT and PfMDR1 in drug accumulation and susceptibility in Plasmodium falciparum. | Molecular microbiology 20111101 |
| Efficacy and safety of artemether-lumefantrine in the treatment of acute, uncomplicated Plasmodium falciparum malaria: a pooled analysis. | The American journal of tropical medicine and hygiene 20111101 |
| A head-to-head comparison of four artemisinin-based combinations for treating uncomplicated malaria in African children: a randomized trial. | PLoS medicine 20111101 |
| Administrative practices of health professionals and use of artesunate-amodiaquine by community members for treating uncomplicated malaria in southern Ghana: implications for artemisinin-based combination therapy deployment. | Tropical medicine & international health : TM & IH 20111001 |
| Exposure, infection, systemic cytokine levels and antibody responses in young children concurrently exposed to schistosomiasis and malaria. | Parasitology 20111001 |
| Drug resistance maps to guide intermittent preventive treatment of malaria in African infants. | Parasitology 20111001 |
| Prolonged selection of pfmdr1 polymorphisms after treatment of falciparum malaria with artemether-lumefantrine in Uganda. | The Journal of infectious diseases 20111001 |
| Drug metabolism by CYP2C8.3 is determined by substrate dependent interactions with cytochrome P450 reductase and cytochrome b5. | Biochemical pharmacology 20110915 |
| Evaluation of CYP2C8 inhibition in vitro: utility of montelukast as a selective CYP2C8 probe substrate. | Drug metabolism and disposition: the biological fate of chemicals 20110901 |
| Azithromycin plus chloroquine: combination therapy for protection against malaria and sexually transmitted infections in pregnancy. | Expert opinion on drug metabolism & toxicology 20110901 |
| Antimalarial mannoxanes: hybrid antimalarial drugs with outstanding oral activity profiles and a potential dual mechanism of action. | ChemMedChem 20110801 |
| Artemisinin-based combination therapy for treating uncomplicated Plasmodium vivax malaria. | The Cochrane database of systematic reviews 20110706 |
| Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites. | Drug metabolism and disposition: the biological fate of chemicals 20110701 |
| Use of the NP-40 detergent-mediated assay in discovery of inhibitors of beta-hematin crystallization. | Antimicrobial agents and chemotherapy 20110701 |
| Buchwald reaction as the key step for the synthesis of metabolically more stable analogs of amodiaquine. | European journal of medicinal chemistry 20110701 |
| Species differences in intestinal metabolic activities of cytochrome P450 isoforms between cynomolgus monkeys and humans. | Drug metabolism and pharmacokinetics 20110601 |
| Therapeutic efficacies of artemisinin-based combination therapies in Nigerian children with uncomplicated falciparum malaria during five years of adoption as first-line treatments. | The American journal of tropical medicine and hygiene 20110601 |
| Therapeutic efficacy and effects of artemether-lumefantrine and artesunate-amodiaquine coformulated or copackaged on malaria-associated anemia in children with uncomplicated Plasmodium falciparum malaria in Southwest Nigeria. | The American journal of tropical medicine and hygiene 20110505 |
| Use of area under the curve to evaluate the effects of antimalarial drugs on malaria-associated anemia after treatment. | American journal of therapeutics 20110501 |
| Malaria in pregnancy: the difficulties in measuring birthweight. | BJOG : an international journal of obstetrics and gynaecology 20110501 |
| In vitro activity of Proveblue (methylene blue) on Plasmodium falciparum strains resistant to standard antimalarial drugs. | Antimicrobial agents and chemotherapy 20110501 |
| Amodiaquine analogues containing NO-donor substructures: synthesis and their preliminary evaluation as potential tools in the treatment of cerebral malaria. | European journal of medicinal chemistry 20110501 |
| Quinine-resistant malaria in traveler returning from French Guiana, 2010. | Emerging infectious diseases 20110501 |
| The impact of retail-sector delivery of artemether-lumefantrine on malaria treatment of children under five in Kenya: a cluster randomized controlled trial. | PLoS medicine 20110501 |
| A cocktail of metabolic probes demonstrates the relevance of primary human hepatocyte cultures in a microfluidic biochip for pharmaceutical drug screening. | International journal of pharmaceutics 20110415 |
| Identification and functional validation of the novel antimalarial resistance locus PF10_0355 in Plasmodium falciparum. | PLoS genetics 20110401 |
| The hydroxyl functionality and a rigid proximal N are required for forming a novel non-covalent quinine-heme complex. | Journal of inorganic biochemistry 20110301 |
| Comparative oral bioavailability of non-fixed and fixed combinations of artesunate and amodiaquine in healthy Indian male volunteers. | European journal of clinical pharmacology 20110301 |
| Follow-up survey of children who received sulfadoxine-pyrimethamine for intermittent preventive antimalarial treatment in infants. | The Journal of infectious diseases 20110215 |
| Intermittent preventive treatment to reduce the burden of malaria in children: new evidence on integration and delivery. | PLoS medicine 20110201 |
| Two strategies for the delivery of IPTc in an area of seasonal malaria transmission in the Gambia: a randomised controlled trial. | PLoS medicine 20110201 |
| Intermittent preventive treatment of malaria provides substantial protection against malaria in children already protected by an insecticide-treated bednet in Mali: a randomised, double-blind, placebo-controlled trial. | PLoS medicine 20110201 |
| Intermittent preventive treatment of malaria provides substantial protection against malaria in children already protected by an insecticide-treated bednet in Burkina Faso: a randomised, double-blind, placebo-controlled trial. | PLoS medicine 20110201 |
| Selective sweeps and genetic lineages of Plasmodium falciparum drug -resistant alleles in Ghana. | The Journal of infectious diseases 20110115 |
| Plasmodium falciparum: Solanum nudum SN-1 steroid antiplasmodial activity when combined with antimalarial drugs. | Experimental parasitology 20110101 |
| Effects of co-administration of artesunate and amodiaquine on some cardiovascular disease indices in rats. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110101 |
| Is parasite clearance clinically important after malaria treatment in a high transmission area? A 3-month follow-up of home-based management with herbal medicine or ACT. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20110101 |
| An in vitro, high throughput, seven CYP cocktail inhibition assay for the evaluation of new chemical entities using LC-MS/MS. | Drug metabolism letters 20110101 |
| Changes in health workers' malaria diagnosis and treatment practices in Kenya. | Malaria journal 20110101 |
| A trial of intermittent preventive treatment and home-based management of malaria in a rural area of The Gambia. | Malaria journal 20110101 |
| Exploring provider and community responses to the new malaria diagnostic and treatment regime in Solomon Islands. | Malaria journal 20110101 |
| Using rapid diagnostic tests as source of malaria parasite DNA for molecular analyses in the era of declining malaria prevalence. | Malaria journal 20110101 |
| Use of the atmospheric generators for capnophilic bacteria Genbag-CO2 for the evaluation of in vitro Plasmodium falciparum susceptibility to standard anti-malarial drugs. | Malaria journal 20110101 |
| Hepatitis C virus infection may lead to slower emergence of P. falciparum in blood. | PloS one 20110101 |
| Pyronaridine-artesunate versus chloroquine in patients with acute Plasmodium vivax malaria: a randomized, double-blind, non-inferiority trial. | PloS one 20110101 |
| Prevalence of resistance associated polymorphisms in Plasmodium falciparum field isolates from southern Pakistan. | Malaria journal 20110101 |
| Evaluation of prevalence's of pfdhfr and pfdhps mutations in Angola. | Malaria journal 20110101 |
| Access to artesunate-amodiaquine, quinine and other anti-malarials: policy and markets in Burundi. | Malaria journal 20110101 |
| Reductions in malaria and anaemia case and death burden at hospitals following scale-up of malaria control in Zanzibar, 1999-2008. | Malaria journal 20110101 |
| A systematic review and meta-analysis of the efficacy and safety of intermittent preventive treatment of malaria in children (IPTc). | PloS one 20110101 |
| A molecular epidemiological study of var gene diversity to characterize the reservoir of Plasmodium falciparum in humans in Africa. | PloS one 20110101 |
| Pharmacokinetics and pharmacodynamics of artesunate and dihydroartemisinin following oral treatment in pregnant women with asymptomatic Plasmodium falciparum infections in Kinshasa DRC. | Malaria journal 20110101 |
| Safety and efficacy of dihydroartemisinin-piperaquine versus artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria in Zambian children. | Malaria journal 20110101 |
| Phase I randomized dose-ascending placebo-controlled trials of ferroquine--a candidate anti-malarial drug--in adults with asymptomatic Plasmodium falciparum infection. | Malaria journal 20110101 |
| Clearance of asymptomatic P. falciparum Infections Interacts with the number of clones to predict the risk of subsequent malaria in Kenyan children. | PloS one 20110101 |
| Effectiveness of artemether-lumefantrine provided by community health workers in under-five children with uncomplicated malaria in rural Tanzania: an open label prospective study. | Malaria journal 20110101 |
| Natural products as starting points for future anti-malarial therapies: going back to our roots? | Malaria journal 20110101 |
| To what extent can traditional medicine contribute a complementary or alternative solution to malaria control programmes? | Malaria journal 20110101 |
| Do ethnobotanical and laboratory data predict clinical safety and efficacy of anti-malarial plants? | Malaria journal 20110101 |
| A 'reverse pharmacology' approach for developing an anti-malarial phytomedicine. | Malaria journal 20110101 |
| Prevalence of molecular markers of anti-malarial drug resistance in Plasmodium vivax and Plasmodium falciparum in two districts of Nepal. | Malaria journal 20110101 |
| Plasmodium falciparum msp1, msp2 and glurp allele frequency and diversity in sub-Saharan Africa. | Malaria journal 20110101 |
| Increasing malaria hospital admissions in Uganda between 1999 and 2009. | BMC medicine 20110101 |
| Determinants of the cost-effectiveness of intermittent preventive treatment for malaria in infants and children. | PloS one 20110101 |
| Protective efficacy of malaria case management and intermittent preventive treatment for preventing malaria mortality in children: a systematic review for the Lives Saved Tool. | BMC public health 20110101 |
| Knowledge and behaviour as determinants of anti-malarial drug use in a peri-urban population from malaria holoendemic region of western Kenya. | Malaria journal 20110101 |
| A study of toxicity and differential gene expression in murine liver following exposure to anti-malarial drugs: amodiaquine and sulphadoxine-pyrimethamine. | Malaria journal 20110101 |
| Modelling the protective efficacy of alternative delivery schedules for intermittent preventive treatment of malaria in infants and children. | PloS one 20110101 |
| Chloroquine resistant vivax malaria in a pregnant woman on the western border of Thailand. | Malaria journal 20110101 |
| Patterns of chloroquine use and resistance in sub-Saharan Africa: a systematic review of household survey and molecular data. | Malaria journal 20110101 |
| Association of severe malaria outcomes with platelet-mediated clumping and adhesion to a novel host receptor. | PloS one 20110101 |
| High prevalence of dhfr triple mutant and correlation with high rates of sulphadoxine-pyrimethamine treatment failures in vivo in Gabonese children. | Malaria journal 20110101 |
| Two-year evaluation of Intermittent Preventive Treatment for Children (IPTc) combined with timely home treatment for malaria control in Ghana. | Malaria journal 20110101 |
| Prevalence and risk factors of malaria among children in southern highland Rwanda. | Malaria journal 20110101 |
| The initial pharmaceutical development of an artesunate/amodiaquine oral formulation for the treatment of malaria: a public-private partnership. | Malaria journal 20110101 |
| Innovative public-private partnerships to maximize the delivery of anti-malarial medicines: lessons learned from the ASAQ Winthrop experience. | Malaria journal 20110101 |
| High frequency of Plasmodium falciparum chloroquine resistance marker (pfcrt T76 mutation) in Yemen: an urgent need to re-examine malaria drug policy. | Parasites & vectors 20110101 |
| Paracetamol versus placebo in treatment of non-severe malaria in children in Guinea-Bissau: a randomized controlled trial. | Malaria journal 20110101 |
| Novel polymorphisms in Plasmodium falciparum ABC transporter genes are associated with major ACT antimalarial drug resistance. | PloS one 20110101 |
| Treatment of uncomplicated malaria at public health facilities and medicine retailers in south-eastern Nigeria. | Malaria journal 20110101 |
| Alternative splicing of the Anopheles gambiae Dscam gene in diverse Plasmodium falciparum infections. | Malaria journal 20110101 |
| Increasing Access to Subsidized Artemisinin-based Combination Therapy through Accredited Drug Dispensing Outlets in Tanzania. | Health research policy and systems 20110101 |
| Acridine and acridinones: old and new structures with antimalarial activity. | The open medicinal chemistry journal 20110101 |
| Clinical trial of extended-dose chloroquine for treatment of resistant falciparum malaria among Afghan refugees in Pakistan. | Malaria journal 20110101 |
| Efficacy of PermaNet® 2.0 and PermaNet® 3.0 against insecticide-resistant Anopheles gambiae in experimental huts in Côte d'Ivoire. | Malaria journal 20110101 |
| Optimal designs for population pharmacokinetic studies of oral artesunate in patients with uncomplicated falciparum malaria. | Malaria journal 20110101 |
| Plasmodium falciparum isolates from southern Ghana exhibit polymorphisms in the SERCA-type PfATPase6 though sensitive to artesunate in vitro. | Malaria journal 20110101 |
| Increase in EPI vaccines coverage after implementation of intermittent preventive treatment of malaria in infant with Sulfadoxine -pyrimethamine in the district of Kolokani, Mali: results from a cluster randomized control trial. | BMC public health 20110101 |
| Antimalarial activity of potential inhibitors of Plasmodium falciparum lactate dehydrogenase enzyme selected by docking studies. | PloS one 20110101 |
| Changing patterns of malaria during 1996-2010 in an area of moderate transmission in southern Senegal. | Malaria journal 20110101 |
| Taking stock: provider prescribing practices in the presence and absence of ACT stock. | Malaria journal 20110101 |
| Exposure to anti-malarial drugs and monitoring of adverse drug reactions using toll-free mobile phone calls in private retail sector in Sagamu, Nigeria: implications for pharmacovigilance. | Malaria journal 20110101 |
| Repeated treatment of recurrent uncomplicated Plasmodium falciparum malaria in Senegal with fixed-dose artesunate plus amodiaquine versus fixed-dose artemether plus lumefantrine: a randomized, open-label trial. | Malaria journal 20110101 |
| Saleability of anti-malarials in private drug shops in Muheza, Tanzania: a baseline study in an era of assumed artemisinin combination therapy (ACT). | Malaria journal 20110101 |
| Feasibility and acceptability of ACT for the community case management of malaria in urban settings in five African sites. | Malaria journal 20110101 |
| Global gene expression profiling of Plasmodium falciparum in response to the anti-malarial drug pyronaridine. | Malaria journal 20110101 |
| Malaria morbidity in children in the year after they had received intermittent preventive treatment of malaria in Mali: a randomized control trial. | PloS one 20110101 |
| Morbidity from malaria in children in the year after they had received intermittent preventive treatment of malaria: a randomised trial. | PloS one 20110101 |
| A cluster-randomized trial of mass drug administration with a gametocytocidal drug combination to interrupt malaria transmission in a low endemic area in Tanzania. | Malaria journal 20110101 |
| Development of ELISA-based methods to measure the anti-malarial drug chloroquine in plasma and in pharmaceutical formulations. | Malaria journal 20110101 |
| Molecular markers of antifolate resistance in Plasmodium falciparum isolates from Luanda, Angola. | Malaria journal 20110101 |
| Host candidate gene polymorphisms and clearance of drug-resistant Plasmodium falciparum parasites. | Malaria journal 20110101 |
| Evaluating health workers' potential resistance to new interventions: a role for discrete choice experiments. | PloS one 20110101 |
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| Protein-based signatures of functional evolution in Plasmodium falciparum. | BMC evolutionary biology 20110101 |
| Reduced in vitro susceptibility to artemisinin derivatives associated with multi-resistance in a traveller returning from South-East Asia. | Malaria journal 20110101 |
| Cost analysis of school-based intermittent screening and treatment of malaria in Kenya. | Malaria journal 20110101 |
| Effects of amodiaquine and artesunate on sulphadoxine-pyrimethamine pharmacokinetic parameters in children under five in Mali. | Malaria journal 20110101 |
| Genetic polymorphism of merozoite surface protein-1 and merozoite surface protein-2 in Plasmodium falciparum isolates from Brazzaville, Republic of Congo. | Malaria journal 20110101 |
| Adherence to prescribed artemisinin-based combination therapy in Garissa and Bunyala districts, Kenya. | Malaria journal 20110101 |
| A new high-throughput method for simultaneous detection of drug resistance associated mutations in Plasmodium vivax dhfr, dhps and mdr1 genes. | Malaria journal 20110101 |
| Prospective study on severe malaria among in-patients at Bombo regional hospital, Tanga, north-eastern Tanzania. | BMC infectious diseases 20110101 |
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| Serological markers suggest heterogeneity of effectiveness of malaria control interventions on Bioko Island, equatorial Guinea. | PloS one 20110101 |
| Risk factors for Plasmodium falciparum hyperparasitaemia in malarious children. | BMC infectious diseases 20110101 |
| Intravenous pharmacokinetics, oral bioavailability, dose proportionality and in situ permeability of anti-malarial lumefantrine in rats. | Malaria journal 20110101 |
| Falciparum malaria in young children of rural Burkina Faso: comparison of survey data in 1999 with 2009. | Malaria journal 20110101 |
| What clinicians who practice in countries reaching malaria elimination should be aware of: lessons learnt from recent experience in Sri Lanka. | Malaria journal 20110101 |
| A thirteen-year analysis of Plasmodium falciparum populations reveals high conservation of the mutant pfcrt haplotype despite the withdrawal of chloroquine from national treatment guidelines in Gabon. | Malaria journal 20110101 |
| Ex vivo susceptibility of Plasmodium falciparum isolates from Dakar, Senegal, to seven standard anti-malarial drugs. | Malaria journal 20110101 |
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| Malaria drug resistance: new observations and developments. | Essays in biochemistry 20110101 |
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| Effects of artesunate on parasite recrudescence and dormancy in the rodent malaria model Plasmodium vinckei. | PloS one 20110101 |
| The ACTwatch project: methods to describe anti-malarial markets in seven countries. | Malaria journal 20110101 |
| Got ACTs? Availability, price, market share and provider knowledge of anti-malarial medicines in public and private sector outlets in six malaria-endemic countries. | Malaria journal 20110101 |
| Rapid evolution of fluoroquinolone-resistant Escherichia coli in Nigeria is temporally associated with fluoroquinolone use. | BMC infectious diseases 20110101 |
| Metal complexes of diisopropylthiourea: synthesis, characterization and antibacterial studies. | International journal of molecular sciences 20110101 |
| A malaria vaccine based on the polymorphic block 2 region of MSP-1 that elicits a broad serotype-spanning immune response. | PloS one 20110101 |
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| Drugs for malaria: something old, something new, something borrowed. | F1000 biology reports 20110101 |
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| A phase III, randomized, non-inferiority trial to assess the efficacy and safety of dihydroartemisinin-piperaquine in comparison with artesunate-mefloquine in patients with uncomplicated Plasmodium falciparum malaria in southern Laos. | The American journal of tropical medicine and hygiene 20101206 |
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| Minimizing analyte electrolysis in electrospray ionization mass spectrometry using a redox buffer coated emitter electrode. | Rapid communications in mass spectrometry : RCM 20100515 |
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| The Plasmodium falciparum-specific human memory B cell compartment expands gradually with repeated malaria infections. | PLoS pathogens 20100501 |
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| Intermittent preventive treatment using artemisinin-based combination therapy reduces malaria morbidity among school-aged children in Mali. | Tropical medicine & international health : TM & IH 20090701 |
| Adherence to artesunate-amodiaquine combination therapy for uncomplicated malaria in children in Zanzibar, Tanzania. | Tropical medicine & international health : TM & IH 20090701 |
| Interference with hemozoin formation represents an important mechanism of schistosomicidal action of antimalarial quinoline methanols. | PLoS neglected tropical diseases 20090701 |
| Focusing on quality patient care in the new global subsidy for malaria medicines. | PLoS medicine 20090701 |
| A microfluidic chip for electrochemical conversions in drug metabolism studies. | Lab on a chip 20090621 |
| In vivo and in vitro efficacy of amodiaquine against Plasmodium falciparum in an area of continued use of 4-aminoquinolines in East Africa. | The Journal of infectious diseases 20090601 |
| Impact of ministry of health interventions on private medicine retailer knowledge and practices on anti-malarial treatment in Kenya. | The American journal of tropical medicine and hygiene 20090601 |
| Efficacy of artemisinin-based combination therapy for treatment of persons with uncomplicated Plasmodium falciparum malaria in West Sumba District, East Nusa Tenggara Province, Indonesia, and genotypic profiles of the parasite. | The American journal of tropical medicine and hygiene 20090601 |
| Severe idiosyncratic drug reaction (Lyells syndrome) after ingesting dihydroartemisinin. | Nigerian journal of clinical practice 20090601 |
| Comparative study of artesunate, ACTs and their combinants on the spermatic parameters of the male guinea pig. | Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria 20090601 |
| Discovery of dual function acridones as a new antimalarial chemotype. | Nature 20090514 |
| Bioelimination of histamine in epithelia of the porcine proximal colon of pigs. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20090501 |
| Open label randomized comparison of dihydroartemisinin-piperaquine and artesunate-amodiaquine for the treatment of uncomplicated Plasmodium falciparum malaria in central Vietnam. | Tropical medicine & international health : TM & IH 20090501 |
| High prevalence of CYP2A6*4 and CYP2A6*9 alleles detected among a Malaysian population. | Clinica chimica acta; international journal of clinical chemistry 20090501 |
| Synthesis, antimalarial activity, and preclinical pharmacology of a novel series of 4'-fluoro and 4'-chloro analogues of amodiaquine. Identification of a suitable 'back-up' compound for N-tert-butyl isoquine. | Journal of medicinal chemistry 20090409 |
| Biological measure of compliance to Artesunate plus Amodiaquine association: interest in a Mono-Desethyl-Amodiaquine blood assay? | Acta tropica 20090401 |
| Replacement of the 4'-hydroxy group of amodiaquine and amopyroquine by aromatic and aliphatic substituents: synthesis and antimalarial activity. | ChemMedChem 20090401 |
| A single LC-tandem mass spectrometry method for the simultaneous determination of 14 antimalarial drugs and their metabolites in human plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090401 |
| Multiple origins and regional dispersal of resistant dhps in African Plasmodium falciparum malaria. | PLoS medicine 20090401 |
| Influence of rapid malaria diagnostic tests on treatment and health outcome in fever patients, Zanzibar: a crossover validation study. | PLoS medicine 20090401 |
| Disruption of a Plasmodium falciparum multidrug resistance-associated protein (PfMRP) alters its fitness and transport of antimalarial drugs and glutathione. | The Journal of biological chemistry 20090320 |
| Candidate selection and preclinical evaluation of N-tert-butyl isoquine (GSK369796), an affordable and effective 4-aminoquinoline antimalarial for the 21st century. | Journal of medicinal chemistry 20090312 |
| Novel metabolites of amodiaquine formed by CYP1A1 and CYP1B1: structure elucidation using electrochemistry, mass spectrometry, and NMR. | Drug metabolism and disposition: the biological fate of chemicals 20090301 |
| In-vivo efficacy of amodiaquine-artesunate in children with uncomplicated Plasmodium falciparum malaria in western Kenya. | Tropical medicine & international health : TM & IH 20090301 |
| Decreasing efficacy of antimalarial combination therapy in Uganda is explained by decreasing host immunity rather than increasing drug resistance. | The Journal of infectious diseases 20090301 |
| Guidelines for field surveys of the quality of medicines: a proposal. | PLoS medicine 20090301 |
| Validation of high performance liquid chromatography-electrochemical detection methods with simultaneous extraction procedure for the determination of artesunate, dihydroartemisinin, amodiaquine and desethylamodiaquine in human plasma for application in clinical pharmacological studies of artesunate-amodiaquine drug combination. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090215 |
| Amodiaquine-induced oxidative stress in a hepatocyte inflammation model. | Toxicology 20090204 |
| Efficacy of monotherapies and artesunate-based combination therapies in children with uncomplicated malaria in Somalia. | Acta tropica 20090201 |
| [Permanent deafness following typhoid fever: case report from Dakar, Senegal]. | Medecine tropicale : revue du Corps de sante colonial 20090201 |
| Bis{(E)-3-[(diethyl-methyl-ammonio)meth-yl]-N-[3-(N,N-dimethyl-sulfamo-yl)-1-methyl-pyridin-4-yl-idene]-4-methoxy-anilinium} tetra-iodide penta-hydrate. | Acta crystallographica. Section E, Structure reports online 20090201 |
| Intermittent preventive treatment with antimalarial drugs. | Lancet (London, England) 20090103 |
| Comparative preclinical drug metabolism and pharmacokinetic evaluation of novel 4-aminoquinoline anti-malarials. | Journal of pharmaceutical sciences 20090101 |
| Screening and characterization of reactive metabolites using glutathione ethyl ester in combination with Q-trap mass spectrometry. | Journal of mass spectrometry : JMS 20090101 |
| Effects of amodiaquine, artesunate, and artesunate-amodiaquine on Plasmodium falciparum malaria-associated anaemia in children. | Acta tropica 20090101 |
| [Two cases of fulminant hepatitis during a curative treatment with an artesunate-amodiaquine combination]. | Medecine et maladies infectieuses 20090101 |
| Dosing accuracy of artesunate and amodiaquine as treatment for falciparum malaria in Casamance, Senegal. | Tropical medicine & international health : TM & IH 20090101 |
| Pattern of drug utilization for treatment of uncomplicated malaria in urban Ghana following national treatment policy change to artemisinin-combination therapy. | Malaria journal 20090101 |
| Mefloquine--an aminoalcohol with promising antischistosomal properties in mice. | PLoS neglected tropical diseases 20090101 |
| Effect of removing direct payment for health care on utilisation and health outcomes in Ghanaian children: a randomised controlled trial. | PLoS medicine 20090101 |
| Artemisinin-based combinations versus amodiaquine plus sulphadoxine-pyrimethamine for the treatment of uncomplicated malaria in Faladje, Mali. | Malaria journal 20090101 |
| Sub-microscopic infections and long-term recrudescence of Plasmodium falciparum in Mozambican pregnant women. | Malaria journal 20090101 |
| Submicroscopic gametocytes and the transmission of antifolate-resistant Plasmodium falciparum in Western Kenya. | PloS one 20090101 |
| Quality of anti-malarial drugs provided by public and private healthcare providers in south-east Nigeria. | Malaria journal 20090101 |
| Clinical trials to estimate the efficacy of preventive interventions against malaria in paediatric populations: a methodological review. | Malaria journal 20090101 |
| Estimating the burden of malaria in pregnancy: a case study from rural Madhya Pradesh, India. | Malaria journal 20090101 |
| Polymorphism of PfATPase in Niger: detection of three new point mutations. | Malaria journal 20090101 |
| Field-based evidence of fast and global increase of Plasmodium falciparum drug-resistance by DNA-microarrays and PCR/RFLP in Niger. | Malaria journal 20090101 |
| A 10 year study of the cause of death in children under 15 years in Manhiça, Mozambique. | BMC public health 20090101 |
| High resistance of Plasmodium falciparum to sulphadoxine/pyrimethamine in northern Tanzania and the emergence of dhps resistance mutation at Codon 581. | PloS one 20090101 |
| Efficacy of chloroquine, amodiaquine and sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria: revisiting molecular markers in an area of emerging AQ and SP resistance in Mali. | Malaria journal 20090101 |
| Extended high efficacy of the combination sulphadoxine-pyrimethamine with artesunate in children with uncomplicated falciparum malaria on the Benin coast, West Africa. | Malaria journal 20090101 |
| Nonradioactive heteroduplex tracking assay for the detection of minority-variant chloroquine-resistant Plasmodium falciparum in Madagascar. | Malaria journal 20090101 |
| The efficacy and safety of a new fixed-dose combination of amodiaquine and artesunate in young African children with acute uncomplicated Plasmodium falciparum. | Malaria journal 20090101 |
| Field-adapted sampling of whole blood to determine the levels of amodiaquine and its metabolite in children with uncomplicated malaria treated with amodiaquine plus artesunate combination. | Malaria journal 20090101 |
| Randomized trial of artesunate+amodiaquine, sulfadoxine-pyrimethamine+amodiaquine, chlorproguanal-dapsone and SP for malaria in pregnancy in Tanzania. | PloS one 20090101 |
| Mefloquine pharmacokinetics and mefloquine-artesunate effectiveness in Peruvian patients with uncomplicated Plasmodium falciparum malaria. | Malaria journal 20090101 |
| Analysis of genetic mutations associated with anti-malarial drug resistance in Plasmodium falciparum from the Democratic Republic of East Timor. | Malaria journal 20090101 |
| Insights into long-lasting protection induced by RTS,S/AS02A malaria vaccine: further results from a phase IIb trial in Mozambican children. | PloS one 20090101 |
| Efficacy and safety of a fixed dose artesunate-sulphamethoxypyrazine-pyrimethamine compared to artemether-lumefantrine for the treatment of uncomplicated falciparum malaria across Africa: a randomized multi-centre trial. | Malaria journal 20090101 |
| The effect of varying analytical methods on estimates of anti-malarial clinical efficacy. | Malaria journal 20090101 |
| Optimization and validation of multi-coloured capillary electrophoresis for genotyping of Plasmodium falciparum merozoite surface proteins (msp1 and 2). | Malaria journal 20090101 |
| In vitro activity of pyronaridine against Plasmodium falciparum and comparative evaluation of anti-malarial drug susceptibility assays. | Malaria journal 20090101 |
| Anti-malarial prescriptions in three health care facilities after the emergence of chloroquine resistance in Niakhar, Senegal (1992-2004). | Malaria journal 20090101 |
| A systematic review and meta-analysis of evidence for correlation between molecular markers of parasite resistance and treatment outcome in falciparum malaria. | Malaria journal 20090101 |
| Strong gametocytocidal effect of methylene blue-based combination therapy against falciparum malaria: a randomised controlled trial. | PloS one 20090101 |
| Chloroquine resistance before and after its withdrawal in Kenya. | Malaria journal 20090101 |
| Therapeutic efficacy of artemether-lumefantrine in uncomplicated falciparum malaria in India. | Malaria journal 20090101 |
| Malaria vectors and transmission dynamics in Goulmoun, a rural city in south-western Chad. | BMC infectious diseases 20090101 |
| Sequence conservation in Plasmodium falciparum alpha-helical coiled coil domains proposed for vaccine development. | PloS one 20090101 |
| Factors related to compliance to anti-malarial drug combination: example of amodiaquine/sulphadoxine-pyrimethamine among children in rural Senegal. | Malaria journal 20090101 |
| Randomized, multicentre assessment of the efficacy and safety of ASAQ--a fixed-dose artesunate-amodiaquine combination therapy in the treatment of uncomplicated Plasmodium falciparum malaria. | Malaria journal 20090101 |
| Plasmodium falciparum genotypes diversity in symptomatic malaria of children living in an urban and a rural setting in Burkina Faso. | Malaria journal 20090101 |
| Efficacy of sulphadoxine-pyrimethamine with or without artesunate for the treatment of uncomplicated Plasmodium falciparum malaria in southern Mozambique: a randomized controlled trial. | Malaria journal 20090101 |
| A comparative, randomized clinical trial of artemisinin/naphtoquine twice daily one day versus artemether/lumefantrine six doses regimen in children and adults with uncomplicated falciparum malaria in Côte d'Ivoire. | Malaria journal 20090101 |
| Chloroquine and sulphadoxine-pyrimethamine sensitivity of Plasmodium falciparum parasites in a Brazilian endemic area. | Malaria journal 20090101 |
| Fever treatment in the absence of malaria transmission in an urban informal settlement in Nairobi, Kenya. | Malaria journal 20090101 |
| Effectiveness of quinine versus artemether-lumefantrine for treating uncomplicated falciparum malaria in Ugandan children: randomised trial. | BMJ (Clinical research ed.) 20090101 |
| A stratified random survey of the proportion of poor quality oral artesunate sold at medicine outlets in the Lao PDR - implications for therapeutic failure and drug resistance. | Malaria journal 20090101 |
| Treatment of malaria from monotherapy to artemisinin-based combination therapy by health professionals in rural health facilities in southern Cameroon. | Malaria journal 20090101 |
| Treatment of malaria from monotherapy to artemisinin-based combination therapy by health professionals in urban health facilities in Yaoundé, central province, Cameroon. | Malaria journal 20090101 |
| Safety and efficacy of dihydroartemisinin-piperaquine in falciparum malaria: a prospective multi-centre individual patient data analysis. | PloS one 20090101 |
| Longitudinal survey of malaria morbidity over 10 years in Saharevo (Madagascar): further lessons for strengthening malaria control. | Malaria journal 20090101 |
| Community response to intermittent preventive treatment of malaria in infants (IPTi) delivered through the expanded programme of immunization in five African settings. | Malaria journal 20090101 |
| Varying efficacy of artesunate+amodiaquine and artesunate+sulphadoxine-pyrimethamine for the treatment of uncomplicated falciparum malaria in the Democratic Republic of Congo: a report of two in-vivo studies. | Malaria journal 20090101 |
| Artemisinin-naphthoquine combination (ARCO) therapy for uncomplicated falciparum malaria in adults of Papua New Guinea: a preliminary report on safety and efficacy. | Malaria journal 20090101 |
| Chlorproguanil-dapsone-artesunate versus artemether-lumefantrine: a randomized, double-blind phase III trial in African children and adolescents with uncomplicated Plasmodium falciparum malaria. | PloS one 20090101 |
| Population pharmacokinetics of artesunate and amodiaquine in African children. | Malaria journal 20090101 |
| Efficacy of artesunate-amodiaquine for treating uncomplicated falciparum malaria in sub-Saharan Africa: a multi-centre analysis. | Malaria journal 20090101 |
| No seasonal accumulation of resistant P. falciparum when high-dose chloroquine is used. | PloS one 20090101 |
| Piloting the global subsidy: the impact of subsidized artemisinin-based combination therapies distributed through private drug shops in rural Tanzania. | PloS one 20090101 |
| Bioavailability of a co-formulated combination of amodiaquine and artesunate under fed and fasted conditions. A randomised, open-label crossover study. | Arzneimittel-Forschung 20090101 |
| PfHRP2 and PfLDH antigen detection for monitoring the efficacy of artemisinin-based combination therapy (ACT) in the treatment of uncomplicated falciparum malaria. | Malaria journal 20090101 |
| Use of the slide positivity rate to estimate changes in malaria incidence in a cohort of Ugandan children. | Malaria journal 20090101 |
| Socio-cultural predictors of health-seeking behaviour for febrile under-five children in Mwanza-Neno district, Malawi. | Malaria journal 20090101 |
| Randomized trial of piperaquine with sulfadoxine-pyrimethamine or dihydroartemisinin for malaria intermittent preventive treatment in children. | PloS one 20090101 |
| Epidemiology of malaria in the forest-savanna transitional zone of Ghana. | Malaria journal 20090101 |
| Seasonal distribution of anti-malarial drug resistance alleles on the island of Sumba, Indonesia. | Malaria journal 20090101 |
| Options for the delivery of intermittent preventive treatment for malaria to children: a community randomised trial. | PloS one 20090101 |
| Simple field assays to check quality of current artemisinin-based antimalarial combination formulations. | PloS one 20090101 |
| Randomized controlled trial of RTS,S/AS02D and RTS,S/AS01E malaria candidate vaccines given according to different schedules in Ghanaian children. | PloS one 20090101 |
| Ongoing challenges in the management of malaria. | Malaria journal 20090101 |
| The clinical efficacy of artemether/lumefantrine (Coartem). | Malaria journal 20090101 |
| Safety profile of Coartem: the evidence base. | Malaria journal 20090101 |
| Impact of the large-scale deployment of artemether/lumefantrine on the malaria disease burden in Africa: case studies of South Africa, Zambia and Ethiopia. | Malaria journal 20090101 |
| Ofloxacin induced leucopenia in complicated falciparum malaria: a case report. | Cases journal 20090101 |
| Population diversity and antibody selective pressure to Plasmodium falciparum MSP1 block2 locus in an African malaria-endemic setting. | BMC microbiology 20090101 |
| The use of schools for malaria surveillance and programme evaluation in Africa. | Malaria journal 20090101 |
| Artemether-lumefantrine in the treatment of uncomplicated Plasmodium falciparum malaria. | Therapeutics and clinical risk management 20090101 |
| Presumptive treatment with sulphadoxine-pyrimethamine versus weekly chloroquine for malaria prophylaxis in children with sickle cell anaemia in Uganda: a randomized controlled trial. | Malaria journal 20090101 |
| A simple cost-effective high performance liquid chromatographic assay of sulphadoxine in whole blood spotted on filter paper for field studies. | Malaria journal 20090101 |
| Reviewing the literature on access to prompt and effective malaria treatment in Kenya: implications for meeting the Abuja targets. | Malaria journal 20090101 |
| Placental malaria among HIV-infected and uninfected women receiving anti-folates in a high transmission area of Uganda. | Malaria journal 20090101 |
| Self-reported data: a major tool to assess compliance with anti-malarial combination therapy among children in Senegal. | Malaria journal 20090101 |
| Access to malaria treatment in young children of rural Burkina Faso. | Malaria journal 20090101 |
| Dihydroartemisinin-piperaquine and artemether-lumefantrine for treating uncomplicated malaria in African children: a randomised, non-inferiority trial. | PloS one 20090101 |
| Evolution of malaria mortality and morbidity after the emergence of chloroquine resistance in Niakhar, Senegal. | Malaria journal 20090101 |
| Ranking malaria risk factors to guide malaria control efforts in African highlands. | PloS one 20090101 |
| Safety and tolerability of artemether-lumefantrine versus dihydroartemisinin-piperaquine for malaria in young HIV-infected and uninfected children. | Malaria journal 20090101 |
| Quality of malaria case management at outpatient health facilities in Angola. | Malaria journal 20090101 |
| Fatal cardiotoxicity related to halofantrine: a review based on a worldwide safety data base. | Malaria journal 20090101 |
| Effectiveness of combined intermittent preventive treatment for children and timely home treatment for malaria control. | Malaria journal 20090101 |
| A comparative study of a flow-cytometry-based assessment of in vitro Plasmodium falciparum drug sensitivity. | Malaria journal 20090101 |
| Residual antimalarials in malaria patients from Tanzania--implications on drug efficacy assessment and spread of parasite resistance. | PloS one 20090101 |
| Effects of mefloquine and artesunate mefloquine on the emergence, clearance and sex ratio of Plasmodium falciparum gametocytes in malarious children. | Malaria journal 20090101 |
| Population pharmacokinetics of artesunate and dihydroartemisinin following single- and multiple-dosing of oral artesunate in healthy subjects. | Malaria journal 20090101 |
| Use and limitations of malaria rapid diagnostic testing by community health workers in war-torn Democratic Republic of Congo. | Malaria journal 20090101 |
| Potential contribution of prescription practices to the emergence and spread of chloroquine resistance in south-west Nigeria: caution in the use of artemisinin combination therapy. | Malaria journal 20090101 |
| Pharmacokinetics and pharmacodynamics of a new ACT formulation: Artesunate/Amodiaquine (TRIMALACT) following oral administration in African malaria patients. | European journal of drug metabolism and pharmacokinetics 20090101 |
| Efficacy of Artesunate + Sulphadoxine-Pyrimethamine (AS + SP) and Amodiaquine + Sulphadoxine-Pyrimethamine (AQ + SP) for Uncomplicated falciparum Malaria in Equatorial Guinea (Central Africa). | Journal of tropical medicine 20090101 |
| Adherence to Artesunate-Amodiaquine Therapy for Uncomplicated Malaria in Rural Ghana: A Randomised Trial of Supervised versus Unsupervised Drug Administration. | Journal of tropical medicine 20090101 |
| Covalent protein modification by reactive drug metabolites using online electrochemistry/liquid chromatography/mass spectrometry. | Analytical chemistry 20081215 |
| Relationships between anaemia and parasitic infections in Kenyan schoolchildren: a Bayesian hierarchical modelling approach. | International journal for parasitology 20081201 |
| Single-dose pharmacokinetic interaction between artesunate and amodiaquine: assembling the clues for the purported interaction. | European journal of clinical pharmacology 20081201 |
| Some features of primary and recrudescent amodiaquine-resistant Plasmodium falciparum infections in Nigerian children. | Memorias do Instituto Oswaldo Cruz 20081201 |
| Plasmodium falciparum: high frequency of pfcrt point mutations and emergence of new mutant haplotypes in Colombia. | Biomedica : revista del Instituto Nacional de Salud 20081201 |
| Amplification of pvmdr1 associated with multidrug-resistant Plasmodium vivax. | The Journal of infectious diseases 20081115 |
| pfmdr1 mutations in imported African Plasmodium falciparum isolates. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20081101 |
| Intermittent preventive antimalarial treatment to children (IPTc): firebreak or fire trap? | Trends in parasitology 20081101 |
| Gametocytes: insights gained during a decade of molecular monitoring. | Trends in parasitology 20081101 |
| Revisiting the design of phase III clinical trials of antimalarial drugs for uncomplicated Plasmodium falciparum malaria. | PLoS medicine 20081101 |
| Comparing highly efficacious antimalarial drugs. | PLoS medicine 20081101 |
| dhfr and dhps genotype and sulfadoxine-pyrimethamine treatment failure in children with falciparum malaria in the Democratic Republic of Congo. | Tropical medicine & international health : TM & IH 20081101 |
| Modelling the impact of artemisinin combination therapy and long-acting treatments on malaria transmission intensity. | PLoS medicine 20081101 |
| (3RS,4SR)-Methyl 4-(2-chloro-5,8-di-methoxy-quinolin-3-yl)-1-phenyl-pyrrolidine-3-carboxyl-ate. | Acta crystallographica. Section E, Structure reports online 20081101 |
| A randomized, controlled trial of intermittent preventive treatment with sulfadoxine-pyrimethamine, amodiaquine, or the combination in pregnant women in Ghana. | The Journal of infectious diseases 20081015 |
| Drugs for treating uncomplicated malaria in pregnant women. | The Cochrane database of systematic reviews 20081008 |
| Pharmacokinetics and clinical efficacy of midazolam in children with severe malaria and convulsions. | British journal of clinical pharmacology 20081001 |
| A randomized, comparative study of supervised and unsupervised artesunate-amodiaquine, for the treatment of uncomplicated malaria in Ghana. | Annals of tropical medicine and parasitology 20081001 |
| Monitoring Plasmodium falciparum chloroquine resistance in Yunnan Province, China, 1981-2006. | Acta tropica 20081001 |
| Deforestation and vectorial capacity of Anopheles gambiae Giles mosquitoes in malaria transmission, Kenya. | Emerging infectious diseases 20081001 |
| Amodiaquine pharmacogenetics. | Pharmacogenomics 20081001 |
| Mutations in PFCRT K76T do not correlate with sulfadoxine-pyrimethamine-amodiaquine failure in Pikine, Senegal. | Parasitology research 20080901 |
| Lysosomal trapping of amodiaquine: impact on transport across intestinal epithelia models. | Biopharmaceutics & drug disposition 20080901 |
| Lysosomotropic drugs inhibit maturation of transforming growth factor-beta. | Canadian journal of physiology and pharmacology 20080901 |
| Synthesis and antimalarial activity of new amino analogues of amodiaquine. | Medicinal chemistry (Shariqah (United Arab Emirates)) 20080901 |
| Effects of amodiaquine hydrochloride and artemisinin on indomethacin-induced lipid peroxidation in rats. | Pakistan journal of biological sciences : PJBS 20080901 |
| Molecular markers of in vivo Plasmodium vivax resistance to amodiaquine plus sulfadoxine-pyrimethamine: mutations in pvdhfr and pvmdr1. | The Journal of infectious diseases 20080801 |
| Adherence and effectiveness of drug combination in curative treatment among children suffering uncomplicated malaria in rural Senegal. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20080801 |
| Artemisinin derivatives and malaria: useful, in combination with other antimalarials. | Prescrire international 20080801 |
| Novel amodiaquine congeners as potent antimalarial agents. | Bioorganic & medicinal chemistry 20080715 |
| Effect of intermittent preventive treatment of malaria on health and education in schoolchildren: a cluster-randomised, double-blind, placebo-controlled trial. | Lancet (London, England) 20080712 |
| Activities of artesunate and amodiaquine against intestinal helminth in children with Plasmodium falciparum malaria in endemic areas. | European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20080701 |
| Pharmacokinetics and tolerability of artesunate and amodiaquine alone and in combination in healthy volunteers. | European journal of clinical pharmacology 20080701 |
| Investigation of amodiaquine bulk drug impurities by liquid chromatography/ion trap mass spectrometry. | Rapid communications in mass spectrometry : RCM 20080701 |
| Dihydrofolate reductase I164L mutation in Plasmodium falciparum, Madagascar. | Emerging infectious diseases 20080701 |
| Biological and haematological safety profile of oral amodiaquine and chloroquine in healthy volunteers with or without Plasmodium falciparum infection in northeast Tanzania. | Tanzania journal of health research 20080701 |
| In vitro evaluations of antimalarial drugs and their relevance to clinical outcomes. | International journal for parasitology 20080601 |
| Effects of revised diagnostic recommendations on malaria treatment practices across age groups in Kenya. | Tropical medicine & international health : TM & IH 20080601 |
| Plasmodium vivax and mixed infections are associated with severe malaria in children: a prospective cohort study from Papua New Guinea. | PLoS medicine 20080601 |
| Multidrug-resistant Plasmodium vivax associated with severe and fatal malaria: a prospective study in Papua, Indonesia. | PLoS medicine 20080601 |
| New medicines for tropical diseases in pregnancy: catch-22. | PLoS medicine 20080601 |
| Effects of artesunate-cotrimoxazole and amodiaquine-artesunate against asexual and sexual stages of Plasmodium falciparum malaria in Nigerian children. | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20080601 |
| [Gametocytemia in falciparum malaria treated with amodiaquine or artesunate]. | Biomedica : revista del Instituto Nacional de Salud 20080601 |
| [In vitro susceptibility of Colombian Plasmodium falciparum isolates to different antimalarial drugs]. | Biomedica : revista del Instituto Nacional de Salud 20080601 |
| Performance of the OptiMAL dipstick in the diagnosis of malaria infection in pregnancy. | Therapeutics and clinical risk management 20080601 |
| The Efficacy of Amodiaquine plus Artesunate Combination in Ghana. | Ghana medical journal 20080601 |
| Effect of folate derivatives on the activity of antifolate drugs used against malaria and cancer. | Parasitology research 20080501 |
| High efficacy of two artemisinin-based combinations (artemether-lumefantrine and artesunate plus amodiaquine) for acute uncomplicated malaria in Ibadan, Nigeria. | Tropical medicine & international health : TM & IH 20080501 |
| Conserved mosquito/parasite interactions affect development of Plasmodium falciparum in Africa. | PLoS pathogens 20080501 |
| Health facility and health worker readiness to deliver new national treatment policy for malaria in Kenya. | East African medical journal 20080501 |
| Two-step synthesis of achiral dispiro-1,2,4,5-tetraoxanes with outstanding antimalarial activity, low toxicity, and high-stability profiles. | Journal of medicinal chemistry 20080410 |
| Selective plasma protein binding of antimalarial drugs to alpha1-acid glycoprotein. | Bioorganic & medicinal chemistry 20080401 |
| The use of artemether-lumefantrine by febrile children following national implementation of a revised drug policy in Kenya. | Tropical medicine & international health : TM & IH 20080401 |
| Electrochemical generation of electrophilic drug metabolites: characterization of amodiaquine quinoneimine and cysteinyl conjugates by MS, IR, and NMR. | Chemical research in toxicology 20080401 |
| Research in complex humanitarian emergencies: the Médecins Sans Frontières/Epicentre experience. | PLoS medicine 20080401 |
| Studies on antimalarial drug susceptibility in Colombia, in relation to Pfmdr1 and Pfcrt. | Parasitology 20080401 |
| High risk of neutropenia in HIV-infected children following treatment with artesunate plus amodiaquine for uncomplicated malaria in Uganda. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080401 |
| Disease and drug interactions: treating malaria with artesunate plus amodiaquine in patients also receiving treatment for concomitant HIV infection. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20080401 |
| Artemether + lumefantrine: new drug. An alternative to atovaquone + proguanil. | Prescrire international 20080401 |
| [Assessing the application of Rwanda's national protocol for uncomplicated malaria treatment in healthcare institutions in Kigali City, Rwanda]. | Medecine et maladies infectieuses 20080301 |
| Increased Plasmodium falciparum gametocyte production in mixed infections with P. malariae. | The American journal of tropical medicine and hygiene 20080301 |
| Efficacy, safety, and selection of molecular markers of drug resistance by two ACTs in Mali. | The American journal of tropical medicine and hygiene 20080301 |
| Clinical diagnosis of malaria and the risk of chloroquine self-medication in rural health centres in Burkina Faso. | Tropical medicine & international health : TM & IH 20080301 |
| Impact of placental Plasmodium falciparum malaria on pregnancy and perinatal outcome in sub-Saharan Africa: part III: placental malaria, maternal health, and public health. | The Yale journal of biology and medicine 20080301 |
| [Efficacy of the amodiaquine+sulfadoxine-pyrimethamine combination and of chloroquine for the treatment of malaria in Córdoba, Colombia, 2006]. | Biomedica : revista del Instituto Nacional de Salud 20080301 |
| Determination of N-desethylamodiaquine by hydrophilic interaction liquid chromatography with tandem mass spectrometry: application to in vitro drug metabolism studies. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080215 |
| Synthesis and antimalarial activity of new analogues of amodiaquine. | European journal of medicinal chemistry 20080201 |
| Synthesis and in vitro cytotoxicity evaluation of 4-aminoquinoline derivatives. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080201 |
| Antimalarial resistance and DHFR/DHPS genotypes of Plasmodium falciparum three years after introduction of sulfadoxine-pyrimethamine and amodiaquine in rural Tanzania. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20080201 |
| Access and barriers to measures targeted to prevent malaria in pregnancy in rural Kenya. | Tropical medicine & international health : TM & IH 20080201 |
| Chloroquine-resistance molecular markers (Pfcrt T76 and Pfmdr-1 Y86) and amodiaquine resistance in Burkina Faso. | Tropical medicine & international health : TM & IH 20080201 |
| Chloroquine resistant Plasmodium falciparum malaria in Osogbo Nigeria: efficacy of amodiaquine + sulfadoxine-pyrimethamine and chloroquine + chlorpheniramine for treatment. | Memorias do Instituto Oswaldo Cruz 20080201 |
| Development of an in vitro assay for the investigation of metabolism-induced drug hepatotoxicity. | Cell biology and toxicology 20080101 |
| The costs of introducing artemisinin-based combination therapy: evidence from district-wide implementation in rural Tanzania. | Malaria journal 20080101 |
| Feasibility and acceptability of artemisinin-based combination therapy for the home management of malaria in four African sites. | Malaria journal 20080101 |
| Malaria risk and access to prevention and treatment in the paddies of the Kilombero Valley, Tanzania. | Malaria journal 20080101 |
| Randomized, comparative study of the efficacy and safety of artesunate plus amodiaquine, administered as a single daily intake versus two daily intakes in the treatment of uncomplicated falciparum malaria. | Malaria journal 20080101 |
| A trial of the efficacy, safety and impact on drug resistance of four drug regimens for seasonal intermittent preventive treatment for malaria in Senegalese children. | PloS one 20080101 |
| From chloroquine to artemether-lumefantrine: the process of drug policy change in Zambia. | Malaria journal 20080101 |
| Clinical malaria in African pregnant women. | Malaria journal 20080101 |
| Why don't health workers prescribe ACT? A qualitative study of factors affecting the prescription of artemether-lumefantrine. | Malaria journal 20080101 |
| Sulphadoxine/pyrimethamine versus amodiaquine for treating uncomplicated childhood malaria in Gabon: a randomized trial to guide national policy. | Malaria journal 20080101 |
| Sulfadoxine-pyrimethamine-based combinations for malaria: a randomised blinded trial to compare efficacy, safety and selection of resistance in Malawi. | PloS one 20080101 |
| Household cost of malaria overdiagnosis in rural Mozambique. | Malaria journal 20080101 |
| Safety and efficacy of methylene blue combined with artesunate or amodiaquine for uncomplicated falciparum malaria: a randomized controlled trial from Burkina Faso. | PloS one 20080101 |
| Risk associated with asymptomatic parasitaemia occurring post-antimalarial treatment. | Tropical medicine & international health : TM & IH 20080101 |
| Translation of artemether-lumefantrine treatment policy into paediatric clinical practice: an early experience from Kenya. | Tropical medicine & international health : TM & IH 20080101 |
| Plasmodium vivax dhfr and dhps mutations in isolates from Madagascar and therapeutic response to sulphadoxine-pyrimethamine. | Malaria journal 20080101 |
| Malaria in rural Mozambique. Part I: children attending the outpatient clinic. | Malaria journal 20080101 |
| Malaria in rural Mozambique. Part II: children admitted to hospital. | Malaria journal 20080101 |
| Open-label comparative clinical study of chlorproguanil-dapsone fixed dose combination (Lapdap) alone or with three different doses of artesunate for uncomplicated Plasmodium falciparum malaria. | PloS one 20080101 |
| Guidelines and mindlines: why do clinical staff over-diagnose malaria in Tanzania? A qualitative study. | Malaria journal 20080101 |
| Can changes in malaria transmission intensity explain prolonged protection and contribute to high protective efficacy of intermittent preventive treatment for malaria in infants? | Malaria journal 20080101 |
| Assessment of the efficacy of antimalarial drugs recommended by the National Malaria Control Programme in Madagascar: up-dated baseline data from randomized and multi-site clinical trials. | Malaria journal 20080101 |
| A randomized placebo-controlled trial of intermittent preventive treatment in pregnant women in the context of insecticide treated nets delivered through the antenatal clinic. | PloS one 20080101 |
| Enhanced efficacy of amodiaquine and chlorpheniramine combination over amodiaquine alone in the treatment of acute uncomplicated Plasmodium falciparum malaria in children. | Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20080101 |
| Efficacy of amodiaquine in the treatment of uncomplicated falciparum malaria in young children of rural north-western Burkina Faso. | Malaria journal 20080101 |
| The usefulness of twenty-four molecular markers in predicting treatment outcome with combination therapy of amodiaquine plus sulphadoxine-pyrimethamine against falciparum malaria in Papua New Guinea. | Malaria journal 20080101 |
| Heterogeneous distribution of Plasmodium falciparum drug resistance haplotypes in subsets of the host population. | Malaria journal 20080101 |
| Antimalarial drug quality in the most severely malarious parts of Africa - a six country study. | PloS one 20080101 |
| Malaria treatment in the retail sector: knowledge and practices of drug sellers in rural Tanzania. | BMC public health 20080101 |
| Duration of protection against malaria and anaemia provided by intermittent preventive treatment in infants in Navrongo, Ghana. | PloS one 20080101 |
| Plasmodium vivax trophozoites insensitive to chloroquine. | Malaria journal 20080101 |
| Substandard anti-malarial drugs in Burkina Faso. | Malaria journal 20080101 |
| A qualitative study of the feasibility and community perception on the effectiveness of artemether-lumefantrine use in the context of home management of malaria in south-west Nigeria. | BMC health services research 20080101 |
| Artemether-lumefantrine versus dihydroartemisinin-piperaquine for treating uncomplicated malaria: a randomized trial to guide policy in Uganda. | PloS one 20080101 |
| Safety and tolerability of combination antimalarial therapies for uncomplicated falciparum malaria in Ugandan children. | Malaria journal 20080101 |
| Monitoring antimalarial safety and tolerability in clinical trials: a case study from Uganda. | Malaria journal 20080101 |
| Activities of artemether-lumefantrine and amodiaquine-sulfalene-pyrimethamine against sexual-stage parasites in falciparum malaria in children. | Chemotherapy 20080101 |
| Depletion of Plasmodium berghei plasmoredoxin reveals a non-essential role for life cycle progression of the malaria parasite. | PloS one 20080101 |
| An open label, randomised trial of artesunate+amodiaquine, artesunate+chlorproguanil-dapsone and artemether-lumefantrine for the treatment of uncomplicated malaria. | PloS one 20080101 |
| Rapid increase of Plasmodium falciparum dhfr/dhps resistant haplotypes, after the adoption of sulphadoxine-pyrimethamine as first line treatment in 2002, in southern Mozambique. | Malaria journal 20080101 |
| Impact of intermittent preventive treatment with sulphadoxine-pyrimethamine targeting the transmission season on the incidence of clinical malaria in children in Mali. | Malaria journal 20080101 |
| Antimalarial drug use in general populations of tropical Africa. | Malaria journal 20080101 |
| Reduction of transmission from malaria patients by artemisinin combination therapies: a pooled analysis of six randomized trials. | Malaria journal 20080101 |
| Amodiaquine-artesunate vs artemether-lumefantrine for uncomplicated malaria in Ghanaian children: a randomized efficacy and safety trial with one year follow-up. | Malaria journal 20080101 |
| Modelling the epidemiological impact of intermittent preventive treatment against malaria in infants. | PloS one 20080101 |
| Presumptive treatment of fever cases as malaria: help or hindrance for malaria control? | Malaria journal 20080101 |
| Antimalarial therapy selection for quinolone resistance among Escherichia coli in the absence of quinolone exposure, in tropical South America. | PloS one 20080101 |
| Early home treatment of childhood fevers with ineffective antimalarials is deleterious in the outcome of severe malaria. | Malaria journal 20080101 |
| Utilization of insecticide-treated nets by under-five children in Nigeria: assessing progress towards the Abuja targets. | Malaria journal 20080101 |
| Molecular epidemiology of drug-resistant malaria in western Kenya highlands. | BMC infectious diseases 20080101 |
| From strategy development to routine implementation: the cost of Intermittent Preventive Treatment in Infants for malaria control. | BMC health services research 20080101 |
| [Efficacy of artemether in the treatment of uncomplicated Plasmodium falciparum malaria in children aged 6-60 months of age in Bangui (Central African Republic)]. | Sante (Montrouge, France) 20080101 |
| Different methodological approaches to the assessment of in vivo efficacy of three artemisinin-based combination antimalarial treatments for the treatment of uncomplicated falciparum malaria in African children. | Malaria journal 20080101 |
| Dynamic RNA profiling in Plasmodium falciparum synchronized blood stages exposed to lethal doses of artesunate. | BMC genomics 20080101 |
| Reduced paediatric hospitalizations for malaria and febrile illness patterns following implementation of community-based malaria control programme in rural Rwanda. | Malaria journal 20080101 |
| Spontaneous adverse drug reaction reporting in rural districts of Mozambique. | Drug safety 20080101 |
| Plasmodium falciparum gametocyte sex ratios in children with acute, symptomatic, uncomplicated infections treated with amodiaquine. | Malaria journal 20080101 |
| Efficacy, safety and tolerability of artesunate-mefloquine in the treatment of uncomplicated Plasmodium falciparum malaria in four geographic zones of Nigeria. | Malaria journal 20080101 |
| Obstacles to prompt and effective malaria treatment lead to low community-coverage in two rural districts of Tanzania. | BMC public health 20080101 |
| Malaria case-management under artemether-lumefantrine treatment policy in Uganda. | Malaria journal 20080101 |
| Effectiveness of artemisinin-based combination therapy used in the context of home management of malaria: a report from three study sites in sub-Saharan Africa. | Malaria journal 20080101 |
| Costs and cost-effectiveness of delivering intermittent preventive treatment through schools in western Kenya. | Malaria journal 20080101 |
| Therapeutic and prophylactic effect of intermittent preventive anti-malarial treatment in infants (IPTi) from Ghana and Gabon. | Malaria journal 20080101 |
| Impact of training in clinical and microscopy diagnosis of childhood malaria on antimalarial drug prescription and health outcome at primary health care level in Tanzania: a randomized controlled trial. | Malaria journal 20080101 |
| Predicting Global Fund grant disbursements for procurement of artemisinin-based combination therapies. | Malaria journal 20080101 |
| Implementation of Home based management of malaria in children reduces the work load for peripheral health facilities in a rural district of Burkina Faso. | Malaria journal 20080101 |
| Determinants of the accuracy of rapid diagnostic tests in malaria case management: evidence from low and moderate transmission settings in the East African highlands. | Malaria journal 20080101 |
| A nationwide survey of the quality of antimalarials in retail outlets in Tanzania. | PloS one 20080101 |
| Artemisinin derivatives versus quinine in treating severe malaria in children: a systematic review. | Malaria journal 20080101 |
| Trends in malaria morbidity following the introduction of artesunate plus amodiaquine combination in M'lomp village dispensary, south-western Senegal. | Malaria journal 20080101 |
| Social and cultural aspects of 'malaria' and its control in central Côte d'Ivoire. | Malaria journal 20080101 |
| Willingness and ability to pay for artemisinin-based combination therapy in rural Tanzania. | Malaria journal 20080101 |
| Overuse of artemisinin-combination therapy in Mto wa Mbu (river of mosquitoes), an area misinterpreted as high endemic for malaria. | Malaria journal 20080101 |
| Implementation of intermittent preventive treatment in pregnancy with sulphadoxine/pyrimethamine (IPTp-SP) at a district health centre in rural Senegal. | Malaria journal 20080101 |
| Prevalence of pfmdr1, pfcrt, pfdhfr and pfdhps mutations associated with drug resistance, in Luanda, Angola. | Malaria journal 20080101 |
| A randomized trial to monitor the efficacy and effectiveness by QT-NASBA of artemether-lumefantrine versus dihydroartemisinin-piperaquine for treatment and transmission control of uncomplicated Plasmodium falciparum malaria in western Kenya. | Malaria journal 20080101 |
| Dispensary level pilot implementation of rapid diagnostic tests: an evaluation of RDT acceptance and usage by providers and patients--Tanzania, 2005. | Malaria journal 20080101 |
| The content of African diets is adequate to achieve optimal efficacy with fixed-dose artemether-lumefantrine: a review of the evidence. | Malaria journal 20080101 |
| Malaria treatment-seeking behaviour and recovery from malaria in a highland area of Kenya. | Malaria journal 20080101 |
| Evaluation of the efficacy and safety of artemether-lumefantrine in the treatment of acute uncomplicated Plasmodium falciparum malaria in Nigerian infants and children. | Malaria journal 20080101 |
| Malariological baseline survey and in vitro antimalarial drug resistance in Gulu district, Northern Uganda. | Wiener klinische Wochenschrift 20080101 |
| Pharmacodynamic interaction between 4-aminoquinolines and retinol in Plasmodium falciparum in vitro. | Wiener klinische Wochenschrift 20080101 |
| Azithromycin-chloroquine and the intermittent preventive treatment of malaria in pregnancy. | Malaria journal 20080101 |
| Survival and haematological recovery of children with severe malaria transfused in accordance to WHO guidelines in Kilifi, Kenya. | Malaria journal 20080101 |
| Does the drug sensitivity of malaria parasites depend on their virulence? | Malaria journal 20080101 |
| The role of anti-malarial drugs in eliminating malaria. | Malaria journal 20080101 |
| Changes in the total leukocyte and platelet counts in Papuan and non Papuan adults from northeast Papua infected with acute Plasmodium vivax or uncomplicated Plasmodium falciparum malaria. | Malaria journal 20080101 |
| Seasonal intermittent preventive treatment for the prevention of anaemia and malaria in Ghanaian children: a randomized, placebo controlled trial. | PloS one 20080101 |
| A randomized trial on effectiveness of artemether-lumefantrine versus artesunate plus amodiaquine for unsupervised treatment of uncomplicated Plasmodium falciparum malaria in Ghanaian children. | Malaria journal 20080101 |
| A randomized, open-label, comparative efficacy trial of artemether-lumefantrine suspension versus artemether-lumefantrine tablets for treatment of uncomplicated Plasmodium falciparum malaria in children in western Kenya. | Malaria journal 20080101 |
| High risk of severe anaemia after chlorproguanil-dapsone+artesunate antimalarial treatment in patients with G6PD (A-) deficiency. | PloS one 20080101 |
| Use of integrated malaria management reduces malaria in Kenya. | PloS one 20080101 |
| The effect of administration of amodiaquine on some parameters of neurobehaviour of Wistar rats. | Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria 20080101 |
| Malaria: uncomplicated, caused by Plasmodium falciparum. | BMJ clinical evidence 20080101 |
| Protective effect of Garcinia kola (kolaviron) extract on predisposition of rats to cardiovascular diseases following separate administration of amodiaquine and artesunate. | African journal of traditional, complementary, and alternative medicines : AJTCAM 20080101 |
| Formulation and Evaluation of Tramadol hydrochloride Rectal Suppositories. | Indian journal of pharmaceutical sciences 20080101 |
| Challenges Associated with Scaling up Artemisinin Combination Therapy in Sub-Saharan Africa A Review Article. | The Libyan journal of medicine 20080101 |
| Randomized comparison of amodiaquine plus sulfadoxine-pyrimethamine, artemether-lumefantrine, and dihydroartemisinin-piperaquine for the treatment of uncomplicated Plasmodium falciparum malaria in Burkina Faso. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20071201 |
| Simultaneous determination of amodiaquine and its active metabolite in human blood by ion-pair liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071201 |
| Intensity of malaria transmission and the spread of Plasmodium falciparum resistant malaria: a review of epidemiologic field evidence. | The American journal of tropical medicine and hygiene 20071201 |
| Short report: polymorphisms in the pfcrt and pfmdr1 genes of Plasmodium falciparum and in vitro susceptibility to amodiaquine and desethylamodiaquine. | The American journal of tropical medicine and hygiene 20071201 |
| Pharmacologic advances in the global control and treatment of malaria: combination therapy and resistance. | Clinical pharmacology and therapeutics 20071101 |
| A field-adapted HPLC method for determination of amodiaquine and its metabolite in whole blood dried on filter paper. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071101 |
| Comparison of the therapeutic efficacy of chloroquine and sulphadoxine-pyremethamine in children and pregnant women. | Tropical medicine & international health : TM & IH 20071101 |
| The safety of amodiaquine use in pregnant women. | Expert opinion on drug safety 20071101 |
| Low efficacy of amodiaquine or chloroquine plus sulfadoxine-pyrimethamine against Plasmodium falciparum and P. vivax malaria in Papua New Guinea. | The American journal of tropical medicine and hygiene 20071101 |
| Impact of artemisinin-based combination therapy and insecticide-treated nets on malaria burden in Zanzibar. | PLoS medicine 20071101 |
| Clinical symptoms, treatment and outcome of highlands malaria in Eldoret (2420 m a.s.l.) and comparison to malaria in hyper-immune population in endemic region of Southern Sudan. | Neuro endocrinology letters 20071101 |
| Population pharmacokinetics of amodiaquine and desethylamodiaquine in pediatric patients with uncomplicated falciparum malaria. | Journal of pharmacokinetics and pharmacodynamics 20071001 |
| Access to health care in contexts of livelihood insecurity: a framework for analysis and action. | PLoS medicine 20071001 |
| Development and validation of a liquid chromatography-mass spectrometry assay for the determination of pyronaridine in human blood for application to clinical pharmacokinetic studies. | Journal of pharmaceutical and biomedical analysis 20070921 |
| Selection of pfmdr1 mutations after amodiaquine monotherapy and amodiaquine plus artemisinin combination therapy in East Africa. | Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20070901 |
| Efficacy of sulfadoxine-pyrimethamine, amodiaquine, and sulfadoxine-pyrimethamine-amodiaquine combination for the treatment of uncomplicated falciparum malaria in the urban and suburban areas of Brazzaville (Congo). | Acta tropica 20070901 |
| Generation and identification of reactive metabolites by electrochemistry and immobilized enzymes coupled on-line to liquid chromatography/mass spectrometry. | Analytical chemistry 20070901 |
| Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20070901 |
| Amodiaquine metabolism is impaired by common polymorphisms in CYP2C8: implications for malaria treatment in Africa. | Clinical pharmacology and therapeutics 20070801 |
| Cardiotoxicity of antimalarial drugs. | The Lancet. Infectious diseases 20070801 |
| Therapeutic efficacy and effects of artemether-lumefantrine and amodiaquine-sulfalene-pyrimethamine on gametocyte carriage in children with uncomplicated Plasmodium falciparum malaria in southwestern Nigeria. | The American journal of tropical medicine and hygiene 20070801 |
| A non-radiolabeled heme-GSH interaction test for the screening of antimalarial compounds. | Experimental parasitology 20070701 |
| The in-vitro susceptibilities of Ghanaian Plasmodium falciparum to antimalarial drugs. | Annals of tropical medicine and parasitology 20070701 |
| In vitro interaction cocktail assay for nine major cytochrome P450 enzymes with 13 probe reactions and a single LC/MSMS run: analytical validation and testing with monoclonal anti-CYP antibodies. | Journal of mass spectrometry : JMS 20070701 |
| Gene encoding a deubiquitinating enzyme is mutated in artesunate- and chloroquine-resistant rodent malaria parasites. | Molecular microbiology 20070701 |
| Artesunate-amodiaquine for the treatment of uncomplicated malaria. | Expert opinion on investigational drugs 20070701 |
| Emergency liver transplantation in amodiaquine-induced fulminant hepatitis. | The American journal of tropical medicine and hygiene 20070701 |
| Amodiaquine in future combination treatment of malaria in Ghana. | Tropical doctor 20070701 |
| Development and validation of a liquid chromatography-mass spectrometry assay for the determination of pyronaridine in human urine. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070615 |
| Shed some light on darkness: will Tanzania reach the millennium development goals? | Acta paediatrica (Oslo, Norway : 1992) 20070601 |
| The great failure of malaria control in Africa: a district perspective from Burkina Faso. | PLoS medicine 20070601 |
| Prevalent pfmdr1 n86y mutant Plasmodium falciparum in Madagascar despite absence of pfcrt mutant strains. | The American journal of tropical medicine and hygiene 20070601 |
| Efficacy of artesunate plus amodiaquine, artesunate plus sulfadoxine-pyrimethamine, and chloroquine plus sulfadoxine-pyrimethamine in patients with uncomplicated Plasmodium falciparum in the Comoros Union. | Acta tropica 20070601 |
| Enhancement of the antimalarial efficacy of amodiaquine by chlorpheniramine in vivo. | Memorias do Instituto Oswaldo Cruz 20070601 |
| Blood schizontocidal activity of methylene blue in combination with antimalarials against Plasmodium falciparum. | Parasite (Paris, France) 20070601 |
| [Polymorphisms of the pfmdr1 gene in field samples of Plasmodium falciparum and their association with therapeutic response to antimalarial drugs and severe malaria in Colombia]. | Biomedica : revista del Instituto Nacional de Salud 20070601 |
| [Tolerance of amodiaquine]. | Medecine tropicale : revue du Corps de sante colonial 20070601 |
| [Open radomized study comparing chloroquine and amodiaquine for treatment of uncomplicated plasmodium falciparum malaria in children in Aboisso, Cote d' Ivoire]. | Medecine tropicale : revue du Corps de sante colonial 20070601 |
| Impact of placental Plasmodium falciparum malaria on pregnancy and perinatal outcome in sub-Saharan Africa: I: introduction to placental malaria. | The Yale journal of biology and medicine 20070601 |
| [A new, cheaper and simpler anti-malaria preparation]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20070531 |
| Antimalarial drugs--here and on the horizon. | JAMA 20070523 |
| Combination therapy for uncomplicated falciparum malaria in Ugandan children: a randomized trial. | JAMA 20070523 |
| Development and evaluation of an electrochemical method for studying reactive phase-I metabolites: correlation to in vitro drug metabolism. | Chemical research in toxicology 20070501 |
| Plasmodium falciparum genotypes associated with chloroquine and amodiaquine resistance in Guinea-Bissau. | The American journal of tropical medicine and hygiene 20070501 |
| Artemether-lumefantrine versus dihydroartemisinin-piperaquine for treatment of malaria: a randomized trial. | PLoS clinical trials 20070501 |
| Response to malaria epidemics in Africa. | Emerging infectious diseases 20070501 |
| Resistance to dihydroartemisinin. | Emerging infectious diseases 20070501 |
| Dihydroartemisinin-piperaquine versus artesunate-amodiaquine: superior efficacy and posttreatment prophylaxis against multidrug-resistant Plasmodium falciparum and Plasmodium vivax malaria. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070415 |
| A randomised trial to assess the safety and efficacy of artemether-lumefantrine (Coartem) for the treatment of uncomplicated Plasmodium falciparum malaria in Rwanda. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20070401 |
| Therapeutic response of multidrug-resistant Plasmodium falciparum and P. vivax to chloroquine and sulfadoxine-pyrimethamine in southern Papua, Indonesia. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20070401 |
| The novel antimalarial compound dioncophylline C forms a complex with heme in solution. | ChemMedChem 20070401 |
| Antimalarial efficacy and drug interactions of the novel semi-synthetic endoperoxide artemisone in vitro and in vivo. | The Journal of antimicrobial chemotherapy 20070401 |
| Effects of prior administration of amodiaquine on the disposition of halofantrine in healthy volunteers. | Therapeutic drug monitoring 20070401 |
| [ASAQ, a breakthrough in the fight against malaria]. | Medecine tropicale : revue du Corps de sante colonial 20070401 |
| Hepatotoxicity due to a drug interaction between amodiaquine plus artesunate and efavirenz. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070315 |
| [Against malaria: ASAQ, one dollar per box]. | Revue medicale suisse 20070314 |
| Effect of amodiaquine, a histamine N-methyltransferase inhibitor, on, Propionibacterium acnes and lipopolysaccharide-induced hepatitis in mice. | European journal of pharmacology 20070308 |
| New once a day, fixed dose antimalarial is now available for adults and children. | BMJ (Clinical research ed.) 20070303 |
| Correlations between treatment outcome and both anti-MSP119 antibody response and erythrocyte-related genetic factors in Plasmodium falciparum malaria. | Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20070301 |
| Different doses of amodiaquine and chloroquine for treatment of uncomplicated malaria in children in Guinea-Bissau: implications for future treatment recommendations. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20070301 |
| Practical HPLC methods for the quantitative determination of common antimalarials in Africa. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070301 |
| Prediction of in vivo potential for metabolic activation of drugs into chemically reactive intermediate: correlation of in vitro and in vivo generation of reactive intermediates and in vitro glutathione conjugate formation in rats and humans. | Chemical research in toxicology 20070301 |
| In vitro assessment of artesunate, artemether and amodiaquine susceptibility and molecular analysis of putative resistance-associated mutations of Plasmodium falciparum from São Tomé and Príncipe. | Tropical medicine & international health : TM & IH 20070301 |
| The comparative efficacies of malartin, with and without amodiaquine, in the treatment of Plasmodium falciparum malaria in the Buea district of Cameroon. | Annals of tropical medicine and parasitology 20070301 |
| Genome-wide linkage analysis of malaria infection intensity and mild disease. | PLoS genetics 20070301 |
| [Assessment of the efficacy of antimalarial drugs in Tarapacá, in the Colombian Amazon basin]. | Biomedica : revista del Instituto Nacional de Salud 20070301 |
| Chloroquine-resistant malaria in Malawi. | The New England journal of medicine 20070222 |
| Antimalarial drug combinations in vastly different settings. | Lancet (London, England) 20070210 |
| Artemether-lumefantrine versus amodiaquine plus sulfadoxine-pyrimethamine for uncomplicated falciparum malaria in Burkina Faso: a randomised non-inferiority trial. | Lancet (London, England) 20070210 |
| Antischistosomal efficacy of artesunate combination therapies administered as curative treatments for malaria attacks. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20070201 |
| Amodiaquine combined with sulfadoxine/pyrimethamine versus artemisinin-based combinations for the treatment of uncomplicated falciparum malaria in Africa: a meta-analysis. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20070201 |
| The effects of artemether-lumefantrine vs amodiaquine-sulfalene-pyrimethamine on the hepatomegaly associated with Plasmodium falciparum malaria in children. | Parasitology research 20070201 |
| CYP2C8 and antimalaria drug efficacy. | Pharmacogenomics 20070201 |
| [Benzo[c][2,7]naphthyridine-5-yl-arylamines-phenol Mannich bases of the amodiaquine-, cycloquine- and pyronaridine-type]. | Die Pharmazie 20070201 |
| In vitro efficacy, resistance selection, and structural modeling studies implicate the malarial parasite apicoplast as the target of azithromycin. | The Journal of biological chemistry 20070126 |
| Rapid dissemination of Plasmodium falciparum drug resistance despite strictly controlled antimalarial use. | PloS one 20070101 |
| Randomized dose-ranging controlled trial of AQ-13, a candidate antimalarial, and chloroquine in healthy volunteers. | PLoS clinical trials 20070101 |
| Modelling the impact of intermittent preventive treatment for malaria on selection pressure for drug resistance. | Malaria journal 20070101 |
| Efficacies of artesunate plus either sulfadoxine-pyrimethamine or amodiaquine, for the treatment of uncomplicated, Plasmodium falciparum malaria in eastern Sudan. | Annals of tropical medicine and parasitology 20070101 |
| Molecular epidemiology of malaria in Cameroon. XXIV. Trends of in vitro antimalarial drug responses in Yaounde, Cameroon. | The American journal of tropical medicine and hygiene 20070101 |
| [Benzo[c][2,7]naphthyridine-5-yl-amines and benzo[h][1,6]naphthyridine-5-yl-amines--potential antimalarials]. | Die Pharmazie 20070101 |
| Intermittent preventive treatment for malaria in pregnancy in Africa: what's new, what's needed? | Malaria journal 20070101 |
| A cost-effectiveness analysis of artemether lumefantrine for treatment of uncomplicated malaria in Zambia. | Malaria journal 20070101 |
| Artemisinin-based combination therapy for uncomplicated Plasmodium falciparum malaria in Colombia. | Malaria journal 20070101 |
| Artesunate--amodiaquine combination therapy for falciparum malaria in young Gabonese children. | Malaria journal 20070101 |
| Microsatellite polymorphism within pfcrt provides evidence of continuing evolution of chloroquine-resistant alleles in Papua New Guinea. | Malaria journal 20070101 |
| Analysis of sulphadoxine/pyrimethamine resistance-conferring mutations of Plasmodium falciparum from Mozambique reveals the absence of the dihydrofolate reductase 164L mutant. | Malaria journal 20070101 |
| Exploration of rate-limiting conformational state for 5-[(7-chloro-4-quinolinyl)amino]-3-[(alkylamino)methyl][1,1'-biphenyl]-2-ols and N(omega)-oxides (tebuquine analogues) for antimalarial activity using molecular shape analysis and molecular field analysis studies. | Journal of chemical information and modeling 20070101 |
| Influence of oxygen on asexual blood cycle and susceptibility of Plasmodium falciparum to chloroquine: requirement of a standardized in vitro assay. | Malaria journal 20070101 |
| Amodiaquine failure associated with erythrocytic glutathione in Plasmodium falciparum malaria. | Malaria journal 20070101 |
| Self-reactivities to the non-erythroid alpha spectrin correlate with cerebral malaria in Gabonese children. | PloS one 20070101 |
| Efficacy of antimalarial treatment in Guinea: in vivo study of two artemisinin combination therapies in Dabola and molecular markers of resistance to sulphadoxine-pyrimethamine in N'Zérékoré. | Malaria journal 20070101 |
| Antimalarial drug prescribing practice in private and public health facilities in South-east Nigeria: a descriptive study. | Malaria journal 20070101 |
| Use of over-the-counter malaria medicines in children and adults in three districts in Kenya: implications for private medicine retailer interventions. | Malaria journal 20070101 |
| Paracheck-Pf accuracy and recently treated Plasmodium falciparum infections: is there a risk of over-diagnosis? | Malaria journal 20070101 |
| Randomized clinical trial of artemisinin versus non-artemisinin combination therapy for uncomplicated falciparum malaria in Madagascar. | Malaria journal 20070101 |
| The challenges of changing national malaria drug policy to artemisinin-based combinations in Kenya. | Malaria journal 20070101 |
| Efficacy and tolerability of four antimalarial combinations in the treatment of uncomplicated Plasmodium falciparum malaria in Senegal. | Malaria journal 20070101 |
| [Place of artemisinin derivatives as anti-malarial drugs in paediatric hospitalization in Abidjan]. | Therapie 20070101 |
| Understanding and improving access to prompt and effective malaria treatment and care in rural Tanzania: the ACCESS Programme. | Malaria journal 20070101 |
| Self-reported use of anti-malarial drugs and health facility management of malaria in Ghana. | Malaria journal 20070101 |
| A comparative study on the efficacy of artesunate plus sulphadoxine/pyrimethamine versus artemether-lumefantrine in eastern Sudan. | Malaria journal 20070101 |
| Community coverage of an antimalarial combination of artesunate and amodiaquine in Makamba Province, Burundi, nine months after its introduction. | Malaria journal 20070101 |
| Severe falciparum malaria in young children of the Kassena-Nankana district of northern Ghana. | Malaria journal 20070101 |
| Assessing malaria control in the Kassena-Nankana district of northern Ghana through repeated surveys using the RBM tools. | Malaria journal 20070101 |
| Battling the malaria iceberg with chloroquine in India. | Malaria journal 20070101 |
| The rationale and plan for creating a World Antimalarial Resistance Network (WARN). | Malaria journal 20070101 |
| World Antimalarial Resistance Network (WARN) II: in vitro antimalarial drug susceptibility. | Malaria journal 20070101 |
| World Antimalarial Resistance Network (WARN) III: molecular markers for drug resistant malaria. | Malaria journal 20070101 |
| World Antimalarial Resistance Network (WARN) IV: clinical pharmacology. | Malaria journal 20070101 |
| Acute childhood diarrhoea in northern Ghana: epidemiological, clinical and microbiological characteristics. | BMC infectious diseases 20070101 |
| Varying efficacy of intermittent preventive treatment for malaria in infants in two similar trials: public health implications. | Malaria journal 20070101 |
| Primaquine clears submicroscopic Plasmodium falciparum gametocytes that persist after treatment with sulphadoxine-pyrimethamine and artesunate. | PloS one 20070101 |
| Antimalarial drug toxicity: a review. | Chemotherapy 20070101 |
| [Therapeutic efficacy of amodiaquine against uncomplicated malaria in Madagascar]. | Sante (Montrouge, France) 20070101 |
| The effect of HIV on morbidity and mortality in children with severe malarial anaemia. | Malaria journal 20070101 |
| Decline of placental malaria in southern Ghana after the implementation of intermittent preventive treatment in pregnancy. | Malaria journal 20070101 |
| Efficacy and safety of artemisinin-based antimalarial in the treatment of uncomplicated malaria in children in southern Tanzania. | Malaria journal 20070101 |
| A randomized controlled pilot trial of azithromycin or artesunate added to sulfadoxine-pyrimethamine as treatment for malaria in pregnant women. | PloS one 20070101 |
| Efficacy and safety of artesunate plus amodiaquine in routine use for the treatment of uncomplicated malaria in Casamance, southern Sénégal. | Malaria journal 20070101 |
| The decline in paediatric malaria admissions on the coast of Kenya. | Malaria journal 20070101 |
| Pilot feasibility study of an emergency paediatric kit for intra-rectal quinine administration used by the personnel of community-based health care units in Senegal. | Malaria journal 20070101 |
| Potential impact of host immunity on malaria treatment outcome in Tanzanian children infected with Plasmodium falciparum. | Malaria journal 20070101 |
| Photophysical properties and photobiological behavior of amodiaquine, primaquine and chloroquine. | Photochemistry and photobiology 20070101 |
| Geometric least squares means ratios for the analysis of Plasmodium falciparum in vitro susceptibility to antimalarial drugs. | Malaria journal 20070101 |
| Intermittent preventive treatment for the prevention of malaria during pregnancy in high transmission areas. | Malaria journal 20070101 |
| Complement activation in Ghanaian children with severe Plasmodium falciparum malaria. | Malaria journal 20070101 |
| Adding artesunate to sulphadoxine-pyrimethamine greatly improves the treatment efficacy in children with uncomplicated falciparum malaria on the coast of Benin, West Africa. | Malaria journal 20070101 |
| Malaria: prevention in travellers. | BMJ clinical evidence 20070101 |
| Safety and efficacy of dihydroartemisinin/piperaquine (Artekin) for the treatment of uncomplicated Plasmodium falciparum malaria in Rwandan children. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20061201 |
| Continued efficacy of sulfadoxine-pyrimethamine as second line treatment for malaria in children in Guinea-Bissau. | Acta tropica 20061201 |
| Amodiaquine resistance is not related to rare findings of pfmdr1 gene amplifications in Kenya. | Tropical medicine & international health : TM & IH 20061201 |
| Rifampicin/Cotrimoxazole/Isoniazid versus mefloquine or quinine + sulfadoxine- pyrimethamine for malaria: a randomized trial. | PLoS clinical trials 20061201 |
| Erythrocyte G protein as a novel target for malarial chemotherapy. | PLoS medicine 20061201 |
| Use of weight-for-age-data to optimize tablet strength and dosing regimens for a new fixed-dose artesunate-amodiaquine combination for treating falciparum malaria. | Bulletin of the World Health Organization 20061201 |
| Effects of pyrimethamine-sulphadoxine, chloroquine plus chlorpheniramine, and amodiaquine plus pyrimethamine-sulphadoxine on gametocytes during and after treatment of acute, uncomplicated malaria in children. | Memorias do Instituto Oswaldo Cruz 20061201 |
| Improved efficacy with amodiaquine instead of chloroquine in sulfadoxine/pyrimethamine combination treatment of falciparum malaria in Uganda: experience with fixed-dose formulation. | Acta tropica 20061101 |
| Amodiaquine, malaria, pregnancy: the old new drug. | Lancet (London, England) 20061014 |
| Efficacy, safety, and tolerability of amodiaquine plus sulphadoxine-pyrimethamine used alone or in combination for malaria treatment in pregnancy: a randomised trial. | Lancet (London, England) 20061014 |
| Artesunate + amodiaquine and artesunate + sulphadoxine-pyrimethamine for treatment of uncomplicated malaria in Democratic Republic of Congo: a clinical trial with determination of sulphadoxine and pyrimethamine-resistant haplotypes. | Tropical medicine & international health : TM & IH 20061001 |
| Cost-effectiveness study of three antimalarial drug combinations in Tanzania. | PLoS medicine 20061001 |
| The potential inhibitory effect of antiparasitic drugs and natural products on P-glycoprotein mediated efflux. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060901 |
| Molecular epidemiology of malaria in Cameroon. XXI. Baseline therapeutic efficacy of chloroquine, amodiaquine, and sulfadoxine-pyrimethamine monotherapies in children before national drug policy change. | The American journal of tropical medicine and hygiene 20060901 |
| A simple technique for the detection of anti-malarial drug formulations and their presence in human urine. | Tanzania health research bulletin 20060901 |
| Heterotropic and homotropic cooperativity by a drug-metabolising mutant of cytochrome P450 BM3. | Biochemical and biophysical research communications 20060804 |
| Factors contributing to the development of anaemia in Plasmodium falciparum malaria: what about drug-resistant parasites? | Journal of tropical pediatrics 20060801 |
| High reinfection rate and treatment failures in children treated with amodiaquine for falciparum malaria in Muheza villages, Northeastern Tanzania. | The American journal of tropical medicine and hygiene 20060801 |
| Amodiaquine resistant Plasmodium falciparum malaria in vivo is associated with selection of pfcrt 76T and pfmdr1 86Y. | Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases 20060701 |
| Amodiaquine, its desethylated metabolite, or both, inhibit the metabolism of debrisoquine (CYP2D6) and losartan (CYP2C9) in vivo. | European journal of clinical pharmacology 20060701 |
| Low efficacy of the combination artesunate plus amodiaquine for uncomplicated falciparum malaria among children under 5 years in Kailahun, Sierra Leone. | Tropical medicine & international health : TM & IH 20060701 |
| High efficacy of two artemisinin-based combinations (artesunate + amodiaquine and artemether + lumefantrine) in Caala, Central Angola. | The American journal of tropical medicine and hygiene 20060701 |
| Association between mutations in Plasmodium falciparum chloroquine resistance transporter and P. falciparum multidrug resistance 1 genes and in vivo amodiaquine resistance in P. falciparum malaria-infected children in Nigeria. | The American journal of tropical medicine and hygiene 20060701 |
| Roles of specific Plasmodium falciparum mutations in resistance to amodiaquine and sulfadoxine-pyrimethamine in Burkina Faso. | The American journal of tropical medicine and hygiene 20060701 |
| Chloroquine/sulphadoxine-pyrimethamine for gambian children with malaria: transmission to mosquitoes of multidrug-resistant Plasmodium falciparum. | PLoS clinical trials 20060701 |
| Randomised trial of chloroquine/sulphadoxine-pyrimethamine in Gambian children with malaria: impact against multidrug-resistant P. falciparum. | PLoS clinical trials 20060701 |
| Relationship between NMR shielding and heme binding strength for a series of 7-substituted quinolines. | The journal of physical chemistry. A 20060629 |
| Occurrence of the Southeast Asian/South American SVMNT haplotype of the chloroquine-resistance transporter gene in Plasmodium falciparum in Tanzania. | The Journal of infectious diseases 20060615 |
| In-vitro susceptibility of Plasmodium falciparum to monodesethylamodiaquine, dihydroartemisinin and quinine in an area of high chloroquine resistance in Rwanda. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20060601 |
| In vitro activity of iron-binding compounds against Senegalese isolates of Plasmodium falciparum. | The Journal of antimicrobial chemotherapy 20060601 |
| Resisting resistance: dealing with the irrepressible problem of malaria. | British journal of clinical pharmacology 20060601 |
| Chloroquine or amodiaquine combined with sulfadoxine-pyrimethamine for uncomplicated malaria: a systematic review. | Tropical medicine & international health : TM & IH 20060601 |
| [Knowledge and practice among health workers from the Thiès region with regard to new malaria treatment policies]. | Sante publique (Vandoeuvre-les-Nancy, France) 20060601 |
| Efficacy of chloroquine, sulfadoxine-pyrimethamine and amodiaquine for treatment of uncomplicated Plasmodium falciparum malaria among children under five in Bongor and Koumra, Chad. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20060501 |
| Modelling malaria control. | PLoS medicine 20060501 |
| Potential impact of intermittent preventive treatment (IPT) on spread of drug-resistant malaria. | PLoS medicine 20060501 |
| Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
| Tolerability of amodiaquine and sulphadoxine-pyrimethamine, alone or in combination for the treatment of uncomplicated Plasmodium falciparum malaria in Rwandan adults. | Tropical medicine & international health : TM & IH 20060501 |
| Susceptibility of Colombian Plasmodium falciparum isolates to 4-aminoquinolines and the definition of amodiaquine resistance in vitro. | Memorias do Instituto Oswaldo Cruz 20060501 |
| RTS,S/AS02A malaria vaccine does not induce parasite CSP T cell epitope selection and reduces multiplicity of infection. | PLoS clinical trials 20060501 |
| Artemisinin combination therapies for treatment of uncomplicated malaria in Uganda. | PLoS clinical trials 20060501 |
| Moderate effect of artemisinin-based combination therapy on transmission of Plasmodium falciparum. | The Journal of infectious diseases 20060415 |
| Amodiaquine polymeric membrane electrode. | Journal of pharmaceutical and biomedical analysis 20060411 |
| A new approach to evaluate stability of amodiaquine and its metabolite in blood and plasma. | Journal of pharmaceutical and biomedical analysis 20060411 |
| Geographic differences in antimalarial drug efficacy in Uganda are explained by differences in endemicity and not by known molecular markers of drug resistance. | The Journal of infectious diseases 20060401 |
| Operational response to malaria epidemics: are rapid diagnostic tests cost-effective? | Tropical medicine & international health : TM & IH 20060401 |
| Microscopy and outpatient malaria case management among older children and adults in Kenya. | Tropical medicine & international health : TM & IH 20060401 |
| Prevalence of malaria parasitemia among clients seeking treatment for fever or malaria at drug stores in rural Tanzania 2004. | Tropical medicine & international health : TM & IH 20060401 |
| The costs of changing national policy: lessons from malaria treatment policy guidelines in Tanzania. | Tropical medicine & international health : TM & IH 20060401 |
| [Thieno[3,2-c]quinoline-4-yl-amines--synthesis and investigation of activity against malaria]. | Die Pharmazie 20060401 |
| Interactions between pairs of antimalarial drugs studied by experimental and ab initio (13)C NMR chemical shifts. | Magnetic resonance in chemistry : MRC 20060301 |
| Storage of antimalarials at household level and associated factors in Kiromo ward, Bagamoyo Tanzania. | African health sciences 20060301 |
| Chemoprophylaxis and malaria death rates. | Emerging infectious diseases 20060301 |
| Sulfadoxine-pyrimethamine plus artesunate versus sulfadoxine-pyrimethamine plus amodiaquine for treating uncomplicated malaria. | The Cochrane database of systematic reviews 20060125 |
| Carbon chemical shift tensor components in quinolines and quinoline N-oxides. | The journal of physical chemistry. A 20060112 |
| Therapeutic efficacy test in malaria falciparum in Antioquia, Colombia. | Malaria journal 20060101 |
| [Cytochrome P-450 and the response to antimalarial drugs]. | Revista panamericana de salud publica = Pan American journal of public health 20060101 |
| Longitudinal study of urban malaria in a cohort of Ugandan children: description of study site, census and recruitment. | Malaria journal 20060101 |
| Rapid Urban Malaria Appraisal (RUMA) III: epidemiology of urban malaria in the municipality of Yopougon (Abidjan). | Malaria journal 20060101 |
| Rapid Urban Malaria Appraisal (RUMA) II: epidemiology of urban malaria in Dar es Salaam (Tanzania). | Malaria journal 20060101 |
| Artemether-lumefantrine versus artesunate plus amodiaquine for treating uncomplicated childhood malaria in Nigeria: randomized controlled trial. | Malaria journal 20060101 |
| An improved high-performance liquid chromatographic determination of chloroquine and its major metabolite, desethylchloroquine, in human plasma. | European journal of drug metabolism and pharmacokinetics 20060101 |
| A medicinal chemistry perspective on 4-aminoquinoline antimalarial drugs. | Current topics in medicinal chemistry 20060101 |
| Rapid Urban Malaria Appraisal (RUMA) IV: epidemiology of urban malaria in Cotonou (Benin). | Malaria journal 20060101 |
| Pattern of cause-specific childhood mortality in a malaria endemic area of Burkina Faso. | Malaria journal 20060101 |
| A database of antimalarial drug resistance. | Malaria journal 20060101 |
| Pharmacovigilance of antimalarial treatment in Africa: is it possible? | Malaria journal 20060101 |
| From chloroquine to artemisinin-based combination therapy: the Sudanese experience. | Malaria journal 20060101 |
| Safety and efficacy of lumefantrine-artemether (Coartem) for the treatment of uncomplicated Plasmodium falciparum malaria in Zambian adults. | Malaria journal 20060101 |
| A fixed-dose 24-hour regimen of artesunate plus sulfamethoxypyrazine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in eastern Sudan. | Annals of clinical microbiology and antimicrobials 20060101 |
| Malaria hotspot areas in a highland Kenya site are consistent in epidemic and non-epidemic years and are associated with ecological factors. | Malaria journal 20060101 |
| Use of pre-packaged chloroquine for the home management of presumed malaria in Malagasy children. | Malaria journal 20060101 |
| Malaria treatment failures after artemisinin-based therapy in three expatriates: could improved manufacturer information help to decrease the risk of treatment failure? | Malaria journal 20060101 |
| Dynamics of immune response and drug resistance in malaria infection. | Malaria journal 20060101 |
| Drug resistance to sulphadoxine-pyrimethamine in Plasmodium falciparum malaria in Mlimba, Tanzania. | Malaria journal 20060101 |
| Literacy and recent history of diarrhoea are predictive of Plasmodium falciparum parasitaemia in Kenyan adults. | Malaria journal 20060101 |
| Spatial and temporal variation in malaria transmission in a low endemicity area in northern Tanzania. | Malaria journal 20060101 |
| Topography and malaria transmission heterogeneity in western Kenya highlands: prospects for focal vector control. | Malaria journal 20060101 |
| Combined chloroquine, sulfadoxine/pyrimethamine and primaquine against Plasmodium falciparum in Central Java, Indonesia. | Malaria journal 20060101 |
| Decreased availability of antimalarials in the private sector following the policy change from chloroquine to sulphadoxine-pyrimethamine in the Kilombero Valley, Tanzania. | Malaria journal 20060101 |
| Early home-based recognition of anaemia via general danger signs, in young children, in a malaria endemic community in north-east Tanzania. | Malaria journal 20060101 |
| Efficacy of three artemisinin combination therapies for the treatment of uncomplicated Plasmodium falciparum malaria in the Republic of Congo. | Malaria journal 20060101 |
| The use of genotyping in antimalarial clinical trials: a systematic review of published studies from 1995-2005. | Malaria journal 20060101 |
| Caregivers' perceived treatment failure in home-based management of fever among Ugandan children aged less than five years. | Malaria journal 20060101 |
| Evaluation of immunomodulators, interferons and known in vitro SARS-coV inhibitors for inhibition of SARS-coV replication in BALB/c mice. | Antiviral chemistry & chemotherapy 20060101 |
| Molecular monitoring of Plasmodium falciparum resistance to artemisinin in Tanzania. | Malaria journal 20060101 |
| Malaria in children: study of 160 cases at a private clinic in Mansehra. | Journal of Ayub Medical College, Abbottabad : JAMC 20060101 |
| Antimalarial drugs in pregnancy: a review. | Current drug safety 20060101 |
| Maternal malaria and gravidity interact to modify infant susceptibility to malaria. | PLoS medicine 20051201 |
| The quality of sulphadoxine-pyrimethamine and amodiaquine products in the Kenyan retail sector. | Journal of clinical pharmacy and therapeutics 20051201 |
| Falciparum malaria in the north of Laos: the occurrence and implications of the Plasmodium falciparum chloroquine resistance transporter (pfcrt) gene haplotype SVMNT. | Tropical medicine & international health : TM & IH 20051201 |
| Short communication: high prevalence of the cytochrome P450 2C8*2 mutation in Northern Ghana. | Tropical medicine & international health : TM & IH 20051201 |
| Rolling back a malaria epidemic in South Africa. | PLoS medicine 20051101 |
| Effect of artemether-lumefantrine policy and improved vector control on malaria burden in KwaZulu-Natal, South Africa. | PLoS medicine 20051101 |
| Open randomized study of artesunate-amodiaquine vs. chloroquine-pyrimethamine-sulfadoxine for the treatment of uncomplicated Plasmodium falciparum malaria in Nigerian children. | Tropical medicine & international health : TM & IH 20051101 |
| Mutations in Plasmodium falciparum dihydrofolate reductase and dihydropteroate synthase genes in Senegal. | Tropical medicine & international health : TM & IH 20051101 |
| Amodiaquine and combination chemotherapy for malaria. | The American journal of tropical medicine and hygiene 20051101 |
| Amodiaquine, sulfadoxine-pyrimethamine, and combination therapy for uncomplicated falciparum malaria: a randomized controlled trial from Burkina Faso. | The American journal of tropical medicine and hygiene 20051101 |
| Differences in willingness to pay for artemisinin-based combinations or monotherapy: experiences from the United Republic of Tanzania. | Bulletin of the World Health Organization 20051101 |
| Structural basis for inhibition of histamine N-methyltransferase by diverse drugs. | Journal of molecular biology 20051021 |
| Chloroquine or amodiaquine combined with sulfadoxine-pyrimethamine for treating uncomplicated malaria. | The Cochrane database of systematic reviews 20051019 |
| Atovaquone-proguanil for treating uncomplicated malaria. | The Cochrane database of systematic reviews 20051019 |
| Artemether-lumefantrine (six-dose regimen) for treating uncomplicated falciparum malaria. | The Cochrane database of systematic reviews 20051019 |
| Efficacy of artesunate plus amodiaquine versus that of artemether-lumefantrine for the treatment of uncomplicated childhood Plasmodium falciparum malaria in Zanzibar, Tanzania. | Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20051015 |
| Therapeutic efficacy of sulfadoxine-pyrimethamine and amodiaquine among children with uncomplicated Plasmodium falciparum malaria in Zanzibar, Tanzania. | The American journal of tropical medicine and hygiene 20051001 |
| Rapid increase in resistance of Plasmodium falciparum to chloroquine-Fansidar in Uganda and the potential of amodiaquine-Fansidar as a better alternative. | Acta tropica 20050901 |
| Comparative efficacy of antimalarial drugs including ACTs in the treatment of uncomplicated malaria among children under 5 years in Ghana. | Acta tropica 20050901 |
| Economic evaluation of a policy change from single-agent treatment for suspected malaria to artesunate-amodiaquine for microscopically confirmed uncomplicated falciparum malaria in the Oussouye District of south-western Senegal. | Tropical medicine & international health : TM & IH 20050901 |
| Blood schizontocidal activity of azithromycin and its combination with alpha/beta arteether against multi-drug resistant Plasmodium yoelii nigeriensis, a novel MDR parasite model for antimalarial screening. | Parasitology 20050901 |
| Malaria in Kenya's western highlands. | Emerging infectious diseases 20050901 |
| [Evaluation of the therapeutic efficacy of amodiaquine versus chloroquine in the treatment of uncomplicated malaria in Abie, Côte-d'Ivoire]. | Bulletin de la Societe de pathologie exotique (1990) 20050901 |
| Interactions of mefloquine with ABC proteins, MRP1 (ABCC1) and MRP4 (ABCC4) that are present in human red cell membranes. | Biochemical pharmacology 20050815 |
| Drug-resistant malaria in Bangui, Central African Republic: an in vitro assessment. | The American journal of tropical medicine and hygiene 20050801 |
| Distinguishing recrudescences from new infections in antimalarial clinical trials: major impact of interpretation of genotyping results on estimates of drug efficacy. | The American journal of tropical medicine and hygiene 20050801 |
| Safety and efficacy of artemether-lumefantrine in the treatment of uncomplicated falciparum malaria in Ethiopia. | East African medical journal 20050801 |
| Malaria in the Nuba Mountains of Sudan: baseline genotypic resistance and efficacy of the artesunate plus sulfadoxine-pyrimethamine and artesunate plus amodiaquine combinations. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20050701 |
| Antimalarial efficacy of chloroquine, amodiaquine, sulfadoxine-pyrimethamine, and the combinations of amodiaquine + artesunate and sulfadoxine-pyrimethamine + artesunate in Huambo and Bie provinces, central Angola. | Transactions of the Royal Society of Tropical Medicine and Hygiene 20050701 |
| Quinoline antimalarials decrease the rate of beta-hematin formation. | Journal of inorganic biochemistry 20050701 |
| Artemisinin versus nonartemisinin combination therapy for uncomplicated malaria: randomized clinical trials from four sites in Uganda. | PLoS medicine 20050701 |
| New malaria combination cheaper and easier to take. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050607 |
| Efficacy of amodiaquine in uncomplicated falciparum malaria in Nigeria in an area with high-level resistance to chloroquine and sulphadoxine/pyrimethamine. | Parasitology research 20050601 |
| A randomized, placebo-controlled, double-blind trial on sulfadoxine-pyrimethamine alone or combined with artesunate or amodiaquine in uncomplicated malaria. | Tropical medicine & international health : TM & IH 20050601 |
| Efficacy of combination therapy with artesunate plus amodiaquine compared to monotherapy with chloroquine, amodiaquine or sulfadoxine-pyrimethamine for treatment of uncomplicated Plasmodium falciparum in Afghanistan. | Tropical medicine & international health : TM & IH 20050601 |
| Chemosusceptibility analysis of Plasmodium falciparum imported malaria in Italy. | Diagnostic microbiology and infectious disease 20050601 |
| Malaria: uncomplicated, caused by Plasmodium falciparum. | Clinical evidence 20050601 |
| New combination drug to treat malaria. | The Lancet. Infectious diseases 20050501 |
| Sulfadoxine-pyrimethamine plus chloroquine or amodiaquine for uncomplicated falciparum malaria: a randomized, multisite trial to guide national policy in Uganda. | The American journal of tropical medicine and hygiene 20050501 |
| Antimalarial drugs: QT prolongation and cardiac arrhythmias. | Expert opinion on drug safety 20050501 |
| Efficacy of chloroquine, amodiaquine, sulfadoxine-pyrimethamine, chloroquine-sulfadoxine-pyrimethamine combination, and amodiaquine-sulfadoxine-pyrimethamine combination in Central African children with noncomplicated malaria. | The American journal of tropical medicine and hygiene 20050501 |
| Reduction of malaria transmission to Anopheles mosquitoes with a six-dose regimen of co-artemether. | PLoS medicine 20050401 |
| The benefits of artemisinin combination therapy for malaria extend beyond the individual patient. | PLoS medicine 20050401 |
| Effectiveness trials in African children with malaria? | Lancet (London, England) 20050401 |
| Amodiaquine alone, amodiaquine+sulfadoxine-pyrimethamine, amodiaquine+artesunate, and artemether-lumefantrine for outpatient treatment of malaria in Tanzanian children: a four-arm randomised effectiveness trial. | Lancet (London, England) 20050401 |
| Selective inhibition of human cytochrome P4502C8 by montelukast. | Drug metabolism and disposition: the biological fate of chemicals 20050301 |
| Pharmacodynamic interactions of amodiaquine and its major metabolite desethylamodiaquine with artemisinin, quinine and atovaquone in Plasmodium falciparum in vitro. | Acta tropica 20050301 |
| A randomized comparative study of chloroquine, amodiaquine and sulphadoxine-pyrimethamine for the treatment of uncomplicated malaria in Ghana. | Tropical medicine & international health : TM & IH 20050301 |
| The disposition of oral amodiaquine in Papua New Guinean children with falciparum malaria. | British journal of clinical pharmacology 20050301 |
| CYP2C8 polymorphism frequencies among malaria patients in Zanzibar. | European journal of clinical pharmacology 20050301 |
| Evidence basis for antimalarial policy change in Sierra Leone: five in vivo efficacy studies of chloroquine, sulphadoxine-pyrimethamine and amodiaquine. | Tropical medicine & international health : TM & IH 20050201 |
| The search for effective and sustainable treatments for Plasmodium falciparum malaria in Africa: a model of the selection of resistance by antifolate drugs and their combinations. | The American journal of tropical medicine and hygiene 20050201 |
| Malaria epidemic and drug resistance, Djibouti. | Emerging infectious diseases 20050201 |
| Examination of 209 drugs for inhibition of cytochrome P450 2C8. | Journal of clinical pharmacology 20050101 |
| Multiple P450 substrates in a single run: rapid and comprehensive in vitro interaction assay. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20050101 |
| Intermittent presumptive treatment for malaria. | PLoS medicine 20050101 |
| Efficacy of two artemisinin combination therapies for uncomplicated falciparum malaria in children under 5 years, Malakal, Upper Nile, Sudan. | Malaria journal 20050101 |
| Comparative effects of fibrates on drug metabolizing enzymes in human hepatocytes. | Pharmaceutical research 20050101 |
| The promise and potential challenges of intermittent preventive treatment for malaria in infants (IPTi). | Malaria journal 20050101 |
| Brands, costs and registration status of antimalarial drugs in the Kenyan retail sector. | Malaria journal 20050101 |
| Antimalarial prescribing practices: a challenge to malaria control in Ghana. | Medical principles and practice : international journal of the Kuwait University, Health Science Centre 20050101 |
| Concurrence of Plasmodium falciparum dhfr and crt mutations in northern Ghana. | Malaria journal 20050101 |
| Rapid urban malaria appraisal (RUMA) I: epidemiology of urban malaria in Ouagadougou. | Malaria journal 20050101 |
| Research influence on antimalarial drug policy change in Tanzania: case study of replacing chloroquine with sulfadoxine-pyrimethamine as the first-line drug. | Malaria journal 20050101 |
| Malaria chemoprophylaxis and the serologic response to measles and diphtheria-tetanus-whole-cell pertussis vaccines. | Malaria journal 20050101 |
| Efficacy of sulfadoxine-pyrimethamine in Tanzania after two years as first-line drug for uncomplicated malaria: assessment protocol and implication for treatment policy strategies. | Malaria journal 20050101 |
| Bone marrow suppression and severe anaemia associated with persistent Plasmodium falciparum infection in African children with microscopically undetectable parasitaemia. | Malaria journal 20050101 |
| Parasitological and clinical efficacy of standard treatment regimens against Plasmodium falciparum, P. vivax and P. malariae in Papua New Guinea. | Papua and New Guinea medical journal 20050101 |
| Evidence for a substrate specific and inhibitable drug efflux system in chloroquine resistant Plasmodium falciparum strains. | Biochemistry 20041228 |
| Structure of the amodiaquine-FPIX mu oxo dimer solution complex at atomic resolution. | Inorganic chemistry 20041213 |
| Amodiaquine during pregnancy. | The Lancet. Infectious diseases 20041201 |
| Principal role of dihydropteroate synthase mutations in mediating resistance to sulfadoxine-pyrimethamine in single-drug and combination therapy of uncomplicated malaria in Uganda. | The American journal of tropical medicine and hygiene 20041201 |
| Combination treatments for uncomplicated falciparum malaria in Kampala, Uganda: randomised clinical trial. | Lancet (London, England) 20041101 |
| Comparison of the parasitologic efficacy of amodiaquine and sulfadoxine-pyrimethamine in the treatment of Plasmodium falciparum malaria in the Bungoma District of western Kenya. | The American journal of tropical medicine and hygiene 20041101 |
| Antileishmanial pyrazolopyridine derivatives: synthesis and structure-activity relationship analysis. | Journal of medicinal chemistry 20041021 |
| Is amodiaquine failing in Rwanda? Efficacy of amodiaquine alone and combined with artesunate in children with uncomplicated malaria. | Tropical medicine & international health : TM & IH 20041001 |
| The difference between effectiveness and efficacy of antimalarial drugs in Kenya. | Tropical medicine & international health : TM & IH 20040901 |
| Efficacy of chloroquine, sulphadoxine-pyrimethamine and amodiaquine for treatment of uncomplicated Plasmodium falciparum malaria in Kajo Keji county, Sudan. | Tropical medicine & international health : TM & IH 20040901 |
| Short report: lack of prediction of amodiaquine efficacy in treating Plasmodium falciparum malaria by in vitro tests. | The American journal of tropical medicine and hygiene 20040901 |
| Risk factors for gametocyte carriage in uncomplicated falciparum malaria in children. | Parasitology 20040901 |
| Plasmodium falciparum hyperparasitaemia in children. Risk factors, treatment outcomes, and gametocytaemia following treatment. | Parasite (Paris, France) 20040901 |
| Evaluation of new cell culture inhibitors of protease-resistant prion protein against scrapie infection in mice. | The Journal of general virology 20040801 |
| The antimalarial potential of 4-quinolinecarbinolamines may be limited due to neurotoxicity and cross-resistance in mefloquine-resistant Plasmodium falciparum strains. | Antimicrobial agents and chemotherapy 20040701 |
| [[1]Benzothieno[3,2-b]pyridin-4-yl-amine--synthesis and investigation of activity against malaria]. | Die Pharmazie 20040701 |
| Validated assays for human cytochrome P450 activities. | Drug metabolism and disposition: the biological fate of chemicals 20040601 |
| Retail supply of malaria-related drugs in rural Tanzania: risks and opportunities. | Tropical medicine & international health : TM & IH 20040601 |
| [Efficacy of therapeutic combinations with artemisinin derivatives in the treatment of non complicated malaria in Burundi]. | Tropical medicine & international health : TM & IH 20040601 |
| Short report: High prevalence of multidrug-resistant Plasmodium falciparum malaria in the French territory of Mayotte. | The American journal of tropical medicine and hygiene 20040601 |
| [Thieno[2,3-c]quinolines - synthesis and biological investigation]. | Die Pharmazie 20040601 |
| [[1]Benzofuro[3,2-b]pyridin-4-yl-amines - synthesis and investigation of activity against malaria]. | Die Pharmazie 20040601 |
| [Combined antimalarial therapy using artemisinin]. | Parassitologia 20040601 |
| Liquid chromatographic determination of amodiaquine in human plasma. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040425 |
| Malaria intermittent preventive treatment in infants, chemoprophylaxis, and childhood vaccinations. | Lancet (London, England) 20040424 |
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| A randomized trial of amodiaquine and artesunate alone and in combination for the treatment of uncomplicated falciparum malaria in children from Burkina Faso. | Tropical medicine & international health : TM & IH 20040401 |
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