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Fursultiamine

CAS No.:
804-30-8
Catalog Number:
AG01CBCQ
Molecular Formula:
C17H26N4O3S2
Molecular Weight:
398.5433
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25mg
98%(HPLC)
In Stock USA
United States
$155
- +
100mg
98%(HPLC)
In Stock USA
United States
$433
- +
1g
98%(HPLC)
In Stock USA
United States
$1261
- +
Product Description
Catalog Number:
AG01CBCQ
Chemical Name:
Fursultiamine
CAS Number:
804-30-8
Molecular Formula:
C17H26N4O3S2
Molecular Weight:
398.5433
MDL Number:
MFCD00867383
IUPAC Name:
N-[(4-amino-2-methylpyrimidin-5-yl)methyl]-N-[(E)-5-hydroxy-3-(oxolan-2-ylmethyldisulfanyl)pent-2-en-2-yl]formamide
InChI:
InChI=1S/C17H26N4O3S2/c1-12(16(5-6-22)26-25-10-15-4-3-7-24-15)21(11-23)9-14-8-19-13(2)20-17(14)18/h8,11,15,22H,3-7,9-10H2,1-2H3,(H2,18,19,20)/b16-12+
InChI Key:
JTLXCMOFVBXEKD-FOWTUZBSSA-N
SMILES:
OCC/C(=C(\N(Cc1cnc(nc1N)C)C=O)/C)/SSCC1CCCO1
EC Number:
212-357-1
Properties
Complexity:
481  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
1  
Exact Mass:
398.145g/mol
Formal Charge:
0
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
398.54g/mol
Monoisotopic Mass:
398.145g/mol
Rotatable Bond Count:
9  
Topological Polar Surface Area:
152A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
XLogP3:
0.6  
Literature
Title Journal
α-Lipoic acid potentially targets AMP-activated protein kinase and energy production in the fetal brain to ameliorate dioxin-produced attenuation in fetal steroidogenesis. The Journal of toxicological sciences 20170101
The effect of thiamin tetrahydrofurfuryl disulfide on behavior of juvenile DBA/2J mice. Neurotoxicology and teratology 20120301
Comparison of the effects of pantethine and fursultiamine on plasma gastrointestinal peptide levels in healthy volunteers. Biological & pharmaceutical bulletin 20110101
Powerful beneficial effects of benfotiamine on cognitive impairment and beta-amyloid deposition in amyloid precursor protein/presenilin-1 transgenic mice. Brain : a journal of neurology 20100501
A thiamin derivative inhibits oxidation of exogenous glucose at rest, but not during exercise. Journal of nutritional science and vitaminology 20100101
Thiamine tetrahydrofurfuryl disulfide improves energy metabolism and physical performance during physical-fatigue loading in rats. Nutrition research (New York, N.Y.) 20091201
A case of anorexia nervosa with Marchiafava-Bignami Disease that responded to high-dose intravenous corticosteroid administration. Psychiatry research 20071115
Human brain activation in response to olfactory stimulation by intravenous administration of odorants. Neuroscience letters 20070809
Stability of cyanocobalamin in sugar-coated tablets. International journal of pharmaceutics 20070607
Myopathy in thiamine deficiency: analysis of a case. Journal of the neurological sciences 20061115
Neuromagnetic changes of brain rhythm evoked by intravenous olfactory stimulation in humans. Brain topography 20060101
Peripheral neuropathy due to thiamine deficiency after inappropriate diet and total gastrectomy. The Tokai journal of experimental and clinical medicine 20050901
Fursultiamine, a vitamin B1 derivative, enhances chondroprotective effects of glucosamine hydrochloride and chondroitin sulfate in rabbit experimental osteoarthritis. Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20050601
ST-segment elevation of electrocardiogram in a patient with Shoshin beriberi. Internal medicine (Tokyo, Japan) 20050601
Thiamine tetrahydrofurfuryl disulfide: a little known therapeutic agent. Medical science monitor : international medical journal of experimental and clinical research 20040901
Treatment of autism spectrum children with thiamine tetrahydrofurfuryl disulfide: a pilot study. Neuro endocrinology letters 20020801
Properties