Pregna-1,4-diene-3,20-dione,6-fluoro-11,21-dihydroxy-16,17-[(1-methylethylidene)bis(oxy)]-,(6a,11b,16a)-
Title | Journal |
---|---|
Utilization of human nuclear receptors as an early counter screen for off-target activity: a case study with a compendium of 615 known drugs. | Toxicological sciences : an official journal of the Society of Toxicology 20150601 |
Regulation of CYP3A genes by glucocorticoids in human lung cells. | F1000Research 20130101 |
Nebulized corticosteroids in asthma and COPD. An Italian appraisal. | Respiratory care 20120701 |
Higher prevalence of obesity among children with asthma. | Obesity (Silver Spring, Md.) 20120501 |
Late (≥ 7 days) inhalation corticosteroids to reduce bronchopulmonary dysplasia in preterm infants. | The Cochrane database of systematic reviews 20120418 |
Effects of add-on therapy with NDC-052, an extract from Magnoliae Flos, in adult asthmatic patients receiving inhaled corticosteroids. | The Korean journal of internal medicine 20120301 |
CYP2S1 is negatively regulated by corticosteroids in human cell lines. | Toxicology letters 20120225 |
Postnatal corticosteroids for prevention and treatment of chronic lung disease in the preterm newborn. | International journal of pediatrics 20120101 |
Is low dose inhaled corticosteroid therapy as effective for inflammation and remodeling in asthma? A randomized, parallel group study. | Respiratory research 20120101 |
Progress in the management of childhood asthma. | Asia Pacific allergy 20120101 |
Recurrent acute rhinosinusitis: a single blind clinical study of N-acetylcysteine vs ambroxol associated to corticosteroid therapy. | International journal of immunopathology and pharmacology 20120101 |
Inhaled chemotherapy in lung cancer: future concept of nanomedicine. | International journal of nanomedicine 20120101 |
The effect of inhaled corticosteroids on hypothalamic-pituitary-adrenal axis. | Indian journal of pharmacology 20120101 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
Hyalinization of the pyloric stomach in CD-1 mice following oral (dietary) administration of the corticosteroid agonists mometasone furoate, budesonide, and flunisolide. | Toxicologic pathology 20111001 |
Linear growth and bone maturation are unaffected by 1 year of therapy with inhaled flunisolide hydrofluoroalkane in prepubescent children with mild persistent asthma: a randomized, double-blind, placebo-controlled trial. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20111001 |
Therapeutic Index (TIX) for intranasal corticosteroids in the treatment of allergic rhinitis. | Rhinology 20110801 |
Psychometric validation of the experience with allergic rhinitis nasal spray questionnaire. | Patient related outcome measures 20110701 |
Activities of aldo-keto reductase 1 enzymes on two inhaled corticosteroids: implications for the pharmacological effects of inhaled corticosteroids. | Chemico-biological interactions 20110530 |
Acute administration of bronchodilators on exercise tolerance in treated COPD patients. | Pulmonary pharmacology & therapeutics 20110201 |
Identification and validation of novel human pregnane X receptor activators among prescribed drugs via ligand-based virtual screening. | Drug metabolism and disposition: the biological fate of chemicals 20110201 |
Mometasone and desloratadine additive effect on eosinophil survival and cytokine secretion from epithelial cells. | Respiratory research 20110101 |
Clinical effectiveness of the Respimat inhaler device in managing chronic obstructive pulmonary disease: evidence when compared with other handheld inhaler devices. | International journal of chronic obstructive pulmonary disease 20110101 |
Pharmacotherapies for chronic obstructive pulmonary disease: a multiple treatment comparison meta-analysis. | Clinical epidemiology 20110101 |
Evaluation of fluticasone propionate and fluticasone propionate/salmeterol combination on exercise in pediatric and adolescent patients with asthma. | The open respiratory medicine journal 20110101 |
Intranasal flunisolide treatment in patients with non-allergic rhinitis. | International journal of immunopathology and pharmacology 20110101 |
iAB-RBC-283: A proteomically derived knowledge-base of erythrocyte metabolism that can be used to simulate its physiological and patho-physiological states. | BMC systems biology 20110101 |
Pharmacotherapy of patients with mild persistent asthma: strategies and unresolved issues. | Frontiers in pharmacology 20110101 |
Lack of paradoxical bronchoconstriction after administration of tiotropium via Respimat® Soft Mist™ Inhaler in COPD. | International journal of chronic obstructive pulmonary disease 20110101 |
Outcomes associated with initiation of tiotropium or fluticasone/salmeterol in patients with chronic obstructive pulmonary disease. | Patient preference and adherence 20110101 |
Optimal management of severe/refractory asthma. | Clinical medicine insights. Circulatory, respiratory and pulmonary medicine 20110101 |
Efficacy in asthma of once-daily treatment with fluticasone furoate: a randomized, placebo-controlled trial. | Respiratory research 20110101 |
Anti-asthma medication prescribing to children in the Lombardy Region of Italy: chronic versus new users. | BMC pulmonary medicine 20110101 |
Severity of COPD at initial spirometry-confirmed diagnosis: data from medical charts and administrative claims. | International journal of chronic obstructive pulmonary disease 20110101 |
Risk of herpes zoster in patients prescribed inhaled corticosteroids: a cohort study. | BMC pulmonary medicine 20110101 |
Understanding and classifying metabolite space and metabolite-likeness. | PloS one 20110101 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
Inter-country variations in anti-asthmatic drug prescriptions for children. Systematic review of studies published during the 2000-2009 period. | European journal of clinical pharmacology 20100901 |
Modulation by flunisolide of tumor necrosis factor-alpha-induced stimulation of airway epithelial cell activities related to eosinophil inflammation. | The Journal of asthma : official journal of the Association for the Care of Asthma 20100501 |
Use of ozone-depleting substances; removal of essential-use designation (flunisolide, etc.). Final rule. | Federal register 20100414 |
The pathophysiology, diagnosis and treatment of allergic rhinitis. | Allergy, asthma & immunology research 20100401 |
Current guidelines for the management of asthma in young children. | Allergy, asthma & immunology research 20100101 |
Treatment of congestion in upper respiratory diseases. | International journal of general medicine 20100101 |
Efficacy and safety of tiotropium Respimat SMI in COPD in two 1-year randomized studies. | International journal of chronic obstructive pulmonary disease 20100101 |
Community based intervention to optimize osteoporosis management: randomized controlled trial. | BMC geriatrics 20100101 |
Clinical utility and patient adherence with ebastine for allergic rhinitis. | Patient preference and adherence 20100101 |
Seasonal allergic rhinitis: fluticasone propionate and fluticasone furoate therapy evaluated. | Journal of asthma and allergy 20100101 |
A systematic review of economic evaluations of therapy in asthma. | Journal of asthma and allergy 20100101 |
The glucocorticoid receptor heterocomplex gene STIP1 is associated with improved lung function in asthmatic subjects treated with inhaled corticosteroids. | The Journal of allergy and clinical immunology 20090601 |
Influence of obesity on bone mineral density in postmenopausal asthma patients undergoing treatment with inhaled corticosteroids. | Clinics (Sao Paulo, Brazil) 20090401 |
A simple and rapid ESI-LC-MS/MS method for simultaneous screening of doping agents in urine samples. | Indian journal of pharmacology 20090401 |
Using nasal steroids to treat nasal obstruction caused by adenoid hypertrophy: does it work? | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20090201 |
Inhaled drugs to reduce exacerbations in patients with chronic obstructive pulmonary disease: a network meta-analysis. | BMC medicine 20090101 |
High-dose inhaled flunisolide versus budesonide in the treatment of acute asthma exacerbations in preschool-age children. | International journal of immunopathology and pharmacology 20090101 |
Asthma patients prefer Respimat Soft Mist Inhaler to Turbuhaler. | International journal of chronic obstructive pulmonary disease 20090101 |
Prevention of surgery in children with adenoidal hypertrophy treated with intranasal flunisolide: a 12-month follow-up. | Journal of biological regulators and homeostatic agents 20090101 |
Drugs associated with more suicidal ideations are also associated with more suicide attempts. | PloS one 20090101 |
Treating rhinitis in the older population: special considerations. | Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20090101 |
Transrepression and transactivation potencies of inhaled glucocorticoids. | Die Pharmazie 20081201 |
Higher lung deposition with Respimat Soft Mist inhaler than HFA-MDI in COPD patients with poor technique. | International journal of chronic obstructive pulmonary disease 20081201 |
Mometasone furoate in the management of asthma: a review. | Therapeutics and clinical risk management 20081201 |
Molecular and clinical pharmacology of intranasal corticosteroids: clinical and therapeutic implications. | Allergy 20081001 |
Pharmacokinetics and tolerability (Study 1) with particular reference to ocular safety (Study 2) of tiotropium Respimat soft mist inhaler: findings from two dose-ranging studies in healthy men. | International journal of chronic obstructive pulmonary disease 20080901 |
Adrenal suppression and Cushing's syndrome secondary to an interaction between ritonavir and fluticasone: a review of the literature. | HIV medicine 20080701 |
Relative oral corticosteroid-sparing effect of 7 inhaled corticosteroids in chronic asthma: a meta-analysis. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20080701 |
Comprehensive screening of acidic and neutral drugs in equine plasma by liquid chromatography-tandem mass spectrometry. | Journal of chromatography. A 20080502 |
Nebulisation of corticosteroid suspensions and solutions with a beta(2) agonist. | The Journal of pharmacy and pharmacology 20080501 |
New treatment options in allergic rhinitis: patient considerations and the role of ciclesonide. | Therapeutics and clinical risk management 20080401 |
The impact of generic-only drug benefits on patients' use of inhaled corticosteroids in a Medicare population with asthma. | BMC health services research 20080101 |
Late development of esophageal stricture following radiation and chemotherapy for small cell carcinoma of the lung: A case report. | Cases journal 20080101 |
Community-based randomised controlled trial evaluating falls and osteoporosis risk management strategies. | Trials 20080101 |
Relative receptor affinity comparisons among inhaled/intranasal corticosteroids: perspectives on clinical relevance. | Respiratory research 20080101 |
Drug use in children: cohort study in three European countries. | BMJ (Clinical research ed.) 20080101 |
Intranasal ciclesonide for allergic rhinitis. | Journal of asthma and allergy 20080101 |
A dose-ranging study of tiotropium delivered via Respimat Soft Mist Inhaler or HandiHaler in COPD patients. | International journal of chronic obstructive pulmonary disease 20071201 |
Strength and endurance of the respiratory and handgrip muscles after the use of flunisolide in normal subjects. | Respiratory medicine 20070701 |
Montelukast in the management of allergic rhinitis. | Therapeutics and clinical risk management 20070601 |
Hypertrichosis as a side effect of inhaled steroids in children. | Pediatric pulmonology 20070401 |
Topical nasal steroids for intermittent and persistent allergic rhinitis in children. | The Cochrane database of systematic reviews 20070124 |
Evidence-based selection of inhaled corticosteroid for treatment of chronic asthma. | The Journal of asthma : official journal of the Association for the Care of Asthma 20070101 |
Human receptor kinetics and lung tissue retention of the enhanced-affinity glucocorticoid fluticasone furoate. | Respiratory research 20070101 |
Compressor/nebulizers differences in the nebulization of corticosteroids. The CODE study (Corticosteroids and Devices Efficiency). | European review for medical and pharmacological sciences 20070101 |
A reappraisal of the clinical efficacy of nebulized flunisolide in pediatric asthma: the Italian experience. | Allergy and asthma proceedings 20070101 |
Intranasal flunisolide treatment in children with adenoidal hypertrophy. | International journal of immunopathology and pharmacology 20070101 |
Pharmacological treatment of chronic obstructive pulmonary disease. | International journal of chronic obstructive pulmonary disease 20061201 |
Topical glucocorticosteroids in rhinitis: clinical aspects. | Acta oto-laryngologica 20061001 |
Use of Respimat Soft Mist inhaler in COPD patients. | International journal of chronic obstructive pulmonary disease 20060901 |
Meta-analysis finds use of inhaled corticosteroids during pregnancy safe: a systematic meta-analysis review. | Human & experimental toxicology 20060801 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
Once-daily intranasal corticosteroids for allergic rhinitis. Examining Treatment issues. | Advance for nurse practitioners 20060401 |
Effects of long-term inhaled corticosteroids on adrenal function in patients with asthma. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20060301 |
Ciclesonide for the treatment of asthma. | Therapeutics and clinical risk management 20060301 |
Efficacy of nebulized flunisolide combined with salbutamol and ipratropium bromide in stable patients with moderate-to-severe chronic obstructive pulmonary disease. | Respiration; international review of thoracic diseases 20060101 |
Budesonide/formoterol and formoterol provide similar rapid relief in patients with acute asthma showing refractoriness to salbutamol. | Respiratory research 20060101 |
Inhaled flunisolide suppresses the hypothalamic-pituitary-adrenocortical axis, but has minimal systemic immune effects in healthy cats. | Journal of veterinary internal medicine 20060101 |
Alternating current electrical stimulation enhanced chemotherapy: a novel strategy to bypass multidrug resistance in tumor cells. | BMC cancer 20060101 |
Flunisolide attenuates nitric oxide-induced DNA damage in rat trachea epithelial cells. | Treatments in respiratory medicine 20060101 |
Flunisolide decreases exhaled nitric oxide and nitrotyrosine levels in asthmatic children. | Mediators of inflammation 20060101 |
Allergic rhinitis: evidence for impact on asthma. | BMC pulmonary medicine 20060101 |
Nebulized drug admixtures: effect on aerosol characteristics and albuterol output. | Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20060101 |
How do topical nasal corticosteroids improve sleep and daytime somnolence in allergic rhinitis? | The Journal of allergy and clinical immunology 20051201 |
Evidence of remodeling in peripheral airways of patients with mild to moderate asthma: effect of hydrofluoroalkane-flunisolide. | The Journal of allergy and clinical immunology 20051101 |
Extrapolation of human pharmacokinetic parameters from rat, dog, and monkey data: Molecular properties associated with extrapolative success or failure. | Journal of pharmaceutical sciences 20050701 |
The nitrosterols--a step forward from the steroid anti-inflammatory drugs? | Expert opinion on investigational drugs 20050701 |
Effects of drug treatment on inflammation and hyperreactivity of airways and on immune variables in cats with experimentally induced asthma. | American journal of veterinary research 20050701 |
Comparison of the analysis of corticosteroids using different techniques. | Analytical and bioanalytical chemistry 20050101 |
Effects of inhaled corticosteroids on bone. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050101 |
Polymorphisms in signal transducer and activator of transcription 3 and lung function in asthma. | Respiratory research 20050101 |
Re-establishment of olfactory and taste functions. | GMS current topics in otorhinolaryngology, head and neck surgery 20050101 |
Quantitative, highly sensitive liquid chromatography-tandem mass spectrometry method for detection of synthetic corticosteroids. | Clinical chemistry 20041201 |
Enhanced anti-inflammatory potency of a nitric oxide-releasing derivative of flunisolide: role of nuclear factor-kappaB. | The Journal of pharmacology and experimental therapeutics 20040901 |
In vitro effects of flunisolide on MMP-9, TIMP-1, fibronectin, TGF-beta1 release and apoptosis in sputum cells freshly isolated from mild to moderate asthmatics. | Allergy 20040901 |
Treatment with inhaled flunisolide. | Chest 20040501 |
Flunisolide HFA for the treatment of asthma: an old friend reformulated. | Expert opinion on pharmacotherapy 20040501 |
[Therapeutic effect of the association between pulmonary ventilation and aerosol--inhalation with sulphureous mineral water in the chronic bronchopneumopathies]. | La Clinica terapeutica 20040401 |
Stability and aerodynamic behaviour of glucocorticoid particles prepared by a supercritical fluids process. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20040301 |
Evaluation of the utilization patterns of leukotriene modifiers in a large managed care health plan. | Journal of managed care pharmacy : JMCP 20040101 |
Treatment of allergic rhinitis during pregnancy. | American journal of rhinology 20040101 |
Hydrofluoroalkane formulations of inhaled corticosteroids for the treatment of asthma. | Treatments in respiratory medicine 20040101 |
Interactions between rhinitis and asthma. | Allergy and asthma proceedings 20040101 |
Significant receptor affinities of metabolites and a degradation product of mometasone furoate. | Respiratory research 20040101 |
Safety and tolerability of treatments for allergic rhinitis in children. | Drug safety 20040101 |
Add-on therapy options in asthma not adequately controlled by inhaled corticosteroids: a comprehensive review. | Respiratory research 20040101 |
[Hydrofluoroalkane as a propellant for pressurized metered-dose inhalers: history, pulmonary deposition, pharmacokinetics, efficacy and safety]. | Jornal de pediatria 20040101 |
Asthma steroid pharmacogenetics: a study strategy to identify replicated treatment responses. | Proceedings of the American Thoracic Society 20040101 |
Actual therapeutic management of allergic and hyperreactive nasal disorders. | GMS current topics in otorhinolaryngology, head and neck surgery 20040101 |
Cost-effectiveness of Advair: fluticasone propionate and salmeterol combination. | Expert review of pharmacoeconomics & outcomes research 20031201 |
Inappropriate use of anti-asthmatic drugs in the Italian paediatric population. | European journal of clinical pharmacology 20031001 |
A randomized controlled trial of inhaled flunisolide in the management of acute asthma in children. | Chest 20030901 |
Effect of topical nasal corticosteroids on patients with chronic fatigue syndrome and rhinitis. | The Journal of the American Osteopathic Association 20030901 |
Relative immunosuppressive potency of therapeutic corticosteroids measured by whole blood lymphocyte proliferation. | Journal of pharmaceutical sciences 20030701 |
Effect of HFA-flunisolide on peripheral lung inflammation in asthma. | The Journal of allergy and clinical immunology 20030701 |
Triple inhaled drug protocol for the treatment of acute severe asthma. | Chest 20030601 |
Fluticasone propionate 100 microg bid using a non-CFC propellant, HFA 134a, in asthmatic children. | Canadian respiratory journal 20030301 |
Evaluation of efficacy and safety of flunisolide hydrofluoroalkane for the treatment of asthma. | Clinical therapeutics 20030301 |
A review of once-daily delivery of anti-asthmatic drugs in children. | Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology 20030201 |
Small airway asthma therapy, challenges, and the future. | Postgraduate medicine 20030201 |
Nasal cellularity in 183 unselected schoolchildren aged 9 to 11 years. | Pediatrics 20021201 |
Intranasal corticosteroids for allergic rhinitis. | Pharmacotherapy 20021101 |
Intranasal corticosteroids versus topical H1 receptor antagonists for the treatment of allergic rhinitis: a systematic review with meta-analysis. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20021101 |
Comparison of high-dose inhaled flunisolide to systemic corticosteroids in severe adult asthma. | Chest 20021001 |
Supercritical fluids crystallization of budesonide and flunisolide. | Pharmaceutical research 20021001 |
Cushing's syndrome, growth impairment, and occult adrenal suppression associated with intranasal steroids. | Archives of disease in childhood 20020701 |
One-year trial on safety and normal linear growth with flunisolide HFA in children with asthma. | Clinical pediatrics 20020601 |
Systemic effect comparisons of six inhaled corticosteroid preparations. | American journal of respiratory and critical care medicine 20020515 |
The output of flunisolide from different nebulisers. | The Journal of pharmacy and pharmacology 20020401 |
[Steroid sprays in non-infectious rhinitis and sinusitis. Proper and regular spraying does not damage the nasal mucosa]. | MMW Fortschritte der Medizin 20020307 |
A comparison of methods for assessing hypothalamic-pituitary-adrenal (HPA) axis activity in asthma patients treated with inhaled corticosteroids. | Journal of clinical pharmacology 20020301 |
Single-dose study to compare the pharmacokinetics of HFA flunisolide and CFC flunisolide. | Journal of pharmaceutical sciences 20020201 |
Therapeutic significance of distal airway inflammation in asthma. | The Journal of allergy and clinical immunology 20020201 |
A meta-analysis of the dose-response relationship of inhaled corticosteroids in adolescents and adults with mild to moderate persistent asthma. | Clinical therapeutics 20020101 |
Clinical review: severe asthma. | Critical care (London, England) 20020101 |
Multiple-dose proportionality study of flunisolide hydrofluoroalkane. | Allergy and asthma proceedings 20020101 |
Flunisolide HFA. | American journal of respiratory medicine : drugs, devices, and other interventions 20020101 |
Poor sleep and daytime somnolence in allergic rhinitis: significance of nasal congestion. | American journal of respiratory medicine : drugs, devices, and other interventions 20020101 |
Evidence of P-glycoprotein mediated apical to basolateral transport of flunisolide in human broncho-tracheal epithelial cells (Calu-3). | British journal of pharmacology 20011201 |
Cost analysis of the use of inhaled corticosteroids in the treatment of asthma: a 1-year follow-up. | Respiratory medicine 20011201 |
Flunisolide HFA vs flunisolide CFC: pharmacokinetic comparison in healthy volunteers. | Biopharmaceutics & drug disposition 20011201 |
Adrenal suppression with inhaled corticosteroids. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20011101 |
Suppression of hypothalamic-pituitary-adrenal axis activity with inhaled flunisolide and fluticasone propionate in adult asthma patients. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20011101 |
Effective control of asthma with hydrofluoroalkane flunisolide delivered as an extrafine aerosol in asthma patients. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20011101 |
Pharmacokinetics of intranasal corticosteroids. | The Journal of allergy and clinical immunology 20010701 |
Improved asthma control after changing from low-to-medium doses of other inhaled corticosteroids to low-dose fluticasone propionate. | MedGenMed : Medscape general medicine 20010608 |
e-NO peak versus e-NO plateau values in evaluating e-NO production in steroid-naive and in steroid-treated asthmatic children and in detecting response to inhaled steroid treatment. | Pediatric pulmonology 20010101 |
Topical corticosteroids in nasal polyposis. | Drugs 20010101 |
Clinical prescribing of allergic rhinitis medication in the preschool and young school-age child: what are the options? | BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20010101 |
Deposition and pharmacokinetics of flunisolide delivered from pressurized inhalers containing non-CFC and CFC propellants. | Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20010101 |
Aerosol characterization of nebulized intranasal glucocorticoid formulations. | Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20010101 |
Metering performance of several metered-dose inhalers with different spacers/holding chambers. | Journal of aerosol medicine : the official journal of the International Society for Aerosols in Medicine 20010101 |
Corticosteroids administered by nebulization to children with bronchial asthma. | Advances in therapy 20010101 |
Transcriptional potencies of inhaled glucocorticoids. | American journal of respiratory and critical care medicine 20000701 |