Role of potassium channels in the antidepressant-like effect of folic acid in the forced swimming test in mice.

Pharmacology, biochemistry, and behavior 20120301

K(ATP) channel openers in the trigeminovascular system.

Cephalalgia : an international journal of headache 20120101

Vasodilator effects of cromakalim and HA 1077 in diabetic rat aorta.

Swiss medical weekly 20120101

The relaxant action of nicorandil in bovine tracheal smooth muscle.

Pharmacology 20120101

A novel cromakalim analogue induces cell cycle arrest and apoptosis in human cervical carcinoma HeLa cells through the caspase- and mitochondria-dependent pathway.

International journal of oncology 20111201

Reopening of ATP-sensitive potassium channels reduces neuropathic pain and regulates astroglial gap junctions in the rat spinal cord.

Pain 20111101

Eicosapentaenoic acid reduces ischemic ventricular fibrillation via altering monophasic action potential in pigs.

Journal of molecular and cellular cardiology 20110901

Interaction of morphine and potassium channel openers on experimental models of pain in mice.

Fundamental & clinical pharmacology 20110801

Modulation of the 6-position of benzopyran derivatives and inhibitory effects on the insulin releasing process.

Bioorganic & medicinal chemistry 20110701

Phasic activity of urinary bladder smooth muscle in the streptozotocin-induced diabetic rat: effect of potassium channel modulators.

European journal of pharmacology 20110625

Impaired vascular responses of insulin-resistant rats after mild subarachnoid hemorrhage.

American journal of physiology. Heart and circulatory physiology 20110601

Nicorandil ameliorates ischaemia-reperfusion injury in the rat kidney.

British journal of pharmacology 20110501

Role of different types of potassium channels and peroxisome proliferator-activated receptors γ in the antidepressant-like activity of bis selenide in the mouse tail suspension test.

Neuroscience letters 20110303

Potassium channel openers exhibit cross-tolerance with morphine in two experimental models of pain.

The West Indian medical journal 20101001

Interspecies differences and extracellular calcium dependence in the vasorelaxing effect of cromakalim in isolated human, porcine, and canine coronary arteries.

Journal of cardiovascular pharmacology and therapeutics 20100901

Evidence of the involvement of K+ channels and PPARgamma receptors in the antidepressant-like activity of diphenyl diselenide in mice.

The Journal of pharmacy and pharmacology 20100901

Direct effect of mild hypothermia on the coronary vasodilation induced by an ATP-sensitive K channel opener, a nitric oxide donor and isoflurane in isolated rat hearts.

Journal of anesthesia 20100801

Effects of K openers on the QT prolongation induced by HERG-blocking drugs in guinea-pigs.

The Journal of pharmacy and pharmacology 20100701

The role of ATP-sensitive potassium channel on acute urinary retention and subsequent catheterization in the rat.

European journal of pharmacology 20100610

K(ATP) channel openers protect mesencephalic neurons against MPP+-induced cytotoxicity via inhibition of ROS production.

Journal of neuroscience research 20100201

Cellular coupling of potassium channels with beta2 adrenoceptors in mediating myometrial relaxation in buffaloes (Bubalus bubalis).

Journal of veterinary pharmacology and therapeutics 20100201

ATP-sensitive potassium channels contribute to the time-dependent alteration in the pentylenetetrazole-induced seizure threshold in diabetic mice.

Seizure 20100101

Assessment of ECG interval and restitution parameters in the canine model of short QT syndrome.

Journal of pharmacological and toxicological methods 20100101

New R/S-3,4-dihydro-2,2-dimethyl-2H-1-benzopyrans as K(ATP) channel openers: modulation of the 4-position.

Bioorganic & medicinal chemistry 20091115

The effect of progesterone on myometrial contractility, potassium channels, and tocolytic efficacy.

Reproductive sciences (Thousand Oaks, Calif.) 20091101

Beneficial effect of propofol on arterial adenosine triphosphate-sensitive K+ channel function impaired by thromboxane.

Anesthesiology 20090801

Prevention of cerebral vasospasm by local delivery of cromakalim with a biodegradable controlled-release system in a rat model of subarachnoid hemorrhage.

Journal of neurosurgery 20090501

Positive inotropic effects of Tityus cambridgei and T. serrulatus scorpion venoms on skeletal muscle.

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20090401

Discovery and structure-activity relationships of a novel series of benzopyran-based K(ATP) openers for urge urinary incontinence.

Bioorganic & medicinal chemistry 20090115

ATP-sensitive K+ channels in pig urethral smooth muscle cells are heteromultimers of Kir6.1 and Kir6.2.

American journal of physiology. Renal physiology 20090101

Vascular effects of estrone and diethylstilbestrol in porcine coronary arteries.

Menopause (New York, N.Y.) 20090101

Role of potassium channels in the relaxant effect of levosimendan in guinea pig tracheal preparations.

Pharmacological reports : PR 20090101

Syntaxin-1A inhibition of P-1075, cromakalim, and diazoxide actions on mouse cardiac ATP-sensitive potassium channel.

Cardiovascular research 20081201

Spirocyclic benzopyran-based derivatives as new anti-ischemic activators of mitochondrial ATP-sensitive potassium channel.

Journal of medicinal chemistry 20081113

QSAR study about ATP-sensitive potassium channel activation of cromakalim analogues using CP-MLR approach.

European journal of medicinal chemistry 20081101

Spontaneous contractions of the pig urinary bladder: the effect of ATP-sensitive potassium channels and the role of the mucosa.

BJU international 20081101

Levcromakalim and MgGDP activate small conductance ATP-sensitive K+ channels of K+ channel pore 6.1/sulfonylurea receptor 2A in pig detrusor smooth muscle cells: uncoupling of cAMP signal pathways.

The Journal of pharmacology and experimental therapeutics 20081001

K+ channel inhibition modulates the biochemical and morphological differentiation of human placental cytotrophoblast cells in vitro.

American journal of physiology. Regulatory, integrative and comparative physiology 20081001

Roles of phosphatidylinositol 3-kinase-Akt and NADPH oxidase in adenosine 5'-triphosphate-sensitive K+ channel function impaired by high glucose in the human artery.

Hypertension (Dallas, Tex. : 1979) 20080901

K(ATP)-mediated vasodilation is impaired in obese Zucker rats.

Microcirculation (New York, N.Y. : 1994) 20080801

Molecular determinants for the activating/blocking actions of the 2H-1,4-benzoxazine derivatives, a class of potassium channel modulators targeting the skeletal muscle KATP channels.

Molecular pharmacology 20080701

Decreased expression of aortic KIR6.1 and SUR2B in hypertension does not correlate with changes in the functional role of K(ATP) channels.

European journal of pharmacology 20080610

Nutritional level and energetic source are determinants of elevated circulatory lipohydroperoxide concentration.

The British journal of nutrition 20080601

Synthesis and activity on rat aorta rings and rat pancreatic beta-cells of ring-opened analogues of benzopyran-type potassium channel activators.

Bioorganic & medicinal chemistry 20080601

[Effects of potassium channel activators on transient inward current in guinea pig ventricular myocytes].

Zhonghua er ke za zhi = Chinese journal of pediatrics 20080601

New R/S-3,4-dihydro-2,2-dimethyl-6-halo-4-(phenylaminothiocarbonylamino)-2H-1-benzopyrans structurally related to (+/-)-cromakalim as tissue-selective pancreatic beta-cell K(ATP) channel openers.

Bioorganic & medicinal chemistry 20080515

K(ATP) channel expression and pharmacological in vivo and in vitro studies of the K(ATP) channel blocker PNU-37883A in rat middle meningeal arteries.

British journal of pharmacology 20080501

Cromakalim activates the K(ATP) and enhances spontaneous transient outward potassium currents in rat saphenous arterial myocytes.

Pharmacological research 20080501

Mitochondrial ATP-sensitive K+ channels regulate NMDAR activity in the cortex of the anoxic western painted turtle.

The Journal of physiology 20080215

The synthesis and biological evaluation of a range of novel functionalized benzopyrans as potential potassium channel activators.

Bioorganic & medicinal chemistry letters 20080201

Inhibitory effects of different ATP-sensitive potassium channel openers on electrically generated and carbachol-induced contractions of porcine and human detrusor muscle.

Fundamental & clinical pharmacology 20080201

Reduced expression of Kir6.2/SUR2A subunits explains KATP deficiency in K+-depleted rats.

Neuromuscular disorders : NMD 20080101

Role of different types of potassium channels in the antidepressant-like effect of agmatine in the mouse forced swimming test.

European journal of pharmacology 20071201

Acute antihypertensive action of Tempol in the spontaneously hypertensive rat.

American journal of physiology. Heart and circulatory physiology 20071201

The endogenous cannabinoid anandamide inhibits cromakalim-activated K+ currents in follicle-enclosed Xenopus oocytes.

The Journal of pharmacology and experimental therapeutics 20071101

Vasorelaxant effect of levcromakalim on isolated umbilical arteries of preeclamptic women.

European journal of obstetrics, gynecology, and reproductive biology 20071001

Time-dependent alteration in cromakalim-induced relaxation of corpus cavernosum from streptozocin-induced diabetic rats.

Life sciences 20070901

Store-refilling involves both L-type calcium channels and reverse-mode sodium-calcium exchange in airway smooth muscle.

The European respiratory journal 20070801

K+ channel modulation of slow wave activity in the guinea-pig prostate.

British journal of pharmacology 20070701

Inhibition of KATP channels in the rat tail artery by neurally released noradrenaline acting on postjunctional alpha2-adrenoceptors.

The Journal of physiology 20070601

Role of ATP-sensitive potassium channels in the biphasic effects of morphine on pentylenetetrazole-induced seizure threshold in mice.

Epilepsy research 20070601

Inhibitory effect of tramadol on vasorelaxation mediated by ATP-sensitive K+ channels in rat aorta.

Canadian journal of anaesthesia = Journal canadien d'anesthesie 20070601

The inhibition of different types of potassium channels underlies the antidepressant-like effect of adenosine in the mouse forced swimming test.

Progress in neuro-psychopharmacology & biological psychiatry 20070413

Smooth muscle mediates circumferential conduction of hyperpolarization and relaxation to focal endothelial cell activation in large coronary arteries.

Naunyn-Schmiedeberg's archives of pharmacology 20070401

Vardenafil increases coronary flow response to hypercapnic acidosis in isolated guinea pig heart.

Basic research in cardiology 20070301

Differential effects of etomidate and midazolam on vascular adenosine triphosphate-sensitive potassium channels: isometric tension and patch clamp studies.

Anesthesiology 20070301

Electrophysiological and pharmacological characterization of the K(ATP) channel involved in the K+-current responses to FSH and adenosine in the follicular cells of Xenopus oocyte.

The journal of physiological sciences : JPS 20070201

Matrix metalloproteinase 2-induced venous dilation via hyperpolarization and activation of K+ channels: relevance to varicose vein formation.

Journal of vascular surgery 20070201

Effect of KATP channel openers on myogenic and neurogenic responses in goat urinary bladder.

Indian journal of experimental biology 20070201

New benzopyran-based openers of the mitochondrial ATP-sensitive potassium channel with potent anti-ischemic properties.

Journal of medicinal chemistry 20061228

Alteration of vascular reactivity in diabetic human mammary artery and the effects of thiazolidinediones.

The Journal of pharmacy and pharmacology 20061201

Opening mitoKATP increases superoxide generation from complex I of the electron transport chain.

American journal of physiology. Heart and circulatory physiology 20061101

Mechanism of reactive oxygen species generation after opening of mitochondrial KATP channels.

American journal of physiology. Heart and circulatory physiology 20061101

Propofol and thiopental attenuate adenosine triphosphate-sensitive potassium channel relaxation in pulmonary veins.

American journal of physiology. Lung cellular and molecular physiology 20061001

Impairment of the vascular relaxation and differential expression of caveolin-1 of the aorta of diabetic +db/+db mice.

European journal of pharmacology 20060928

Activation of the iberiotoxin-sensitive BKCa channels by salvianolic acid B of the porcine coronary artery smooth muscle cells.

European journal of pharmacology 20060928

Beat-to-Beat variability of repolarization determines proarrhythmic outcome in dogs susceptible to drug-induced torsades de pointes.

Journal of the American College of Cardiology 20060919

The role of potassium channels in the vasodilatory effect of levosimendan in human internal thoracic arteries.

European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery 20060801

Design, synthesis, and pharmacological evaluation of R/S-3,4-dihydro-2,2-dimethyl- 6-halo-4-(phenylaminocarbonylamino)-2H-1-benzopyrans: toward tissue-selective pancreatic beta-cell KATP channel openers structurally related to (+/-)-cromakalim.

Journal of medicinal chemistry 20060727

Efficacy of different vasodilators on human umbilical arterial smooth muscle under normal and reduced oxygen conditions.

Early human development 20060701

Synthetic peroxisome proliferator-activated receptor-gamma agonists restore impaired vasorelaxation via ATP-sensitive K+ channels by high glucose.

The Journal of pharmacology and experimental therapeutics 20060701

The potassium channel opener levcromakalim causes expansive remodelling of experimental vein grafts.

Journal of vascular surgery 20060701

Synthesis and pharmacological evaluation of some N-arylsulfonyl-N-methyl-N'-(2,2-dimethyl-2H-1-benzopyran-4-yl)ureas structurally related to cromakalim.

Bioorganic & medicinal chemistry 20060515

L-beta,beta-dimethylcysteine attenuates the haemodynamic responses elicited by systemic injections of peroxynitrite in anaesthetized rats.

British journal of pharmacology 20060501

The role of potassium channels in relaxant effect of levosimendan in rat small mesenteric arteries.

Cardiovascular drugs and therapy 20060401

Augmented activity of adenosine triphosphate-sensitive K+ channels induced by droperidol in the rat aorta.

Anesthesia and analgesia 20060301

Pharmacological characterization of urinary bladder smooth muscle contractility following partial bladder outlet obstruction in pigs.

European journal of pharmacology 20060217

Different glibenclamide-sensitivity of ATP-sensitive K+ currents using different patch-clamp recording methods.

European journal of pharmacology 20060215

Effects of mitiglinide and sulfonylureas in isolated canine coronary arteries and perfused rat hearts.

European journal of pharmacology 20060215

Evidence that inward rectifier K+ channels mediate relaxation by the PGI2 receptor agonist cicaprost via a cyclic AMP-independent mechanism.

Cardiovascular research 20060101

Investigation of the relaxant effects of pinacidil and cromakalim on the sheep sphincter of Oddi.

Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20060101

From cromakalim to different structural classes of K(ATP) channel openers.

Current topics in medicinal chemistry 20060101

Activation of endothelial NADPH oxidase during normoxic lung ischemia is KATP channel dependent.

American journal of physiology. Lung cellular and molecular physiology 20051201

Multiple actions of U-37883A, an ATP-sensitive K+ channel blocker, on membrane currents in pig urethra.

European journal of pharmacology 20051107

Role of SHP-1, Kv.1.2, and cGMP in nitric oxide-induced ERK1/2 MAP kinase dephosphorylation in rat vascular smooth muscle cells.

Cardiovascular research 20051101

Loss of K+ATP-channel-mediated vasodilation after induction of tachyphylaxis to peroxynitrite.

Journal of cardiovascular pharmacology 20051101

Role of ATP-sensitive K+ -channels in hemodynamic effects of peroxynitrite in anesthetized rats.

Journal of cardiovascular pharmacology 20051101

Sulphonylurea receptors differently modulate ICC pacemaker Ca2+ activity and smooth muscle contractility.

Journal of cell science 20050915

Antispasmodic and blood pressure lowering effects of Valeriana wallichii are mediated through K+ channel activation.

Journal of ethnopharmacology 20050914

Role of nitric oxide scavenging in vascular response to cell-free hemoglobin transfusion.

American journal of physiology. Heart and circulatory physiology 20050901

Heat shock protein modulation of KATP and KCa channel cerebrovasodilation after brain injury.

American journal of physiology. Heart and circulatory physiology 20050901

The diacylglycerol lipase inhibitor RHC-80267 potentiates the relaxation to acetylcholine in rat mesenteric artery by anti-cholinesterase action.

European journal of pharmacology 20050704

SUR, ABC proteins targeted by KATP channel openers.

Journal of molecular and cellular cardiology 20050601

Doxapram stimulates the carotid body via a different mechanism than hypoxic chemotransduction.

Respiratory physiology & neurobiology 20050512

150-kD oxygen-regulated protein is an essential factor for insulin release.

Pancreas 20050501

Endogenous hydrogen peroxide regulates the excitability of midbrain dopamine neurons via ATP-sensitive potassium channels.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20050427

Role of KATP channels in the regulation of rat dura and pia artery diameter.

Cephalalgia : an international journal of headache 20050401

Alteration of cyclopiazonic acid-mediated contracture of mouse diaphragm after denervation.

Pharmacology 20050301

Inhibitory effects of lidocaine and mexiletine on vasorelaxation mediated by adenosine triphosphate-sensitive K+ channels and the role of kinases in the porcine coronary artery.

Anesthesiology 20050301

Changes in pH increase perfusion pressure of coronary arteries in the rat.

Journal of pharmacological sciences 20050301

Involvement of adenosine triphosphate-sensitive potassium channels in the response of membrane potential to hyperosmolality in cultured human aorta endothelial cells.

Anesthesia and analgesia 20050201

4,6-Disubstituted 2,2-dimethylchromans structurally related to the K(ATP) channel opener cromakalim: design, synthesis, and effect on insulin release and vascular tone.

Journal of medicinal chemistry 20050127

KATP-channel-induced vasodilation is modulated by the Na,K-pump activity in rabbit coronary small arteries.

British journal of pharmacology 20041201

Effect of two amino acids in TM17 of Sulfonylurea receptor SUR1 on the binding of ATP-sensitive K+ channel modulators.

Diabetes 20041201

Effect of chronic insulin on cromakalim-induced relaxation in established streptozotocin-diabetic rat basilar artery.

European journal of pharmacology 20041103

Altered vascular reactivity and KATP channel currents in vascular smooth muscle cells from deoxycorticosterone acetate (DOCA)-salt hypertensive rats.

Journal of cardiovascular pharmacology 20041101

Pathophysiological plasma ET-1 levels antagonize beta-adrenergic dilation of coronary resistance vessels in conscious dogs.

American journal of physiology. Heart and circulatory physiology 20041001

Lys-[Leu8,des-Arg9]-bradykinin blocks lipopolysaccharide-induced SHR aorta hyperpolarization by inhibition of Ca(++)- and ATP-dependent K+ channels.

European journal of pharmacology 20040913

Visceral periadventitial adipose tissue regulates arterial tone of mesenteric arteries.

Hypertension (Dallas, Tex. : 1979) 20040901

Lidocaine impairs vasodilation mediated by adenosine triphosphate-sensitive K+ channels but not by inward rectifier K+ channels in rat cerebral microvessels.

Anesthesia and analgesia 20040901

Role of adenosine triphosphate-dependent potassium channels in canine penile erection.

Urology 20040901

Ca2+ flux through voltage-gated channels with flow cessation in pulmonary microvascular endothelial cells.

Microcirculation (New York, N.Y. : 1994) 20040901

The synergistic effect of adenosine A2A receptors agonist, type IV phosphodiestease inhibitor and ATP-sensitive K channels activation on free radicals production and aggregation of human polymorphoneuclear leukocytes.

Pharmacological research 20040801

The protective effect of protein kinase C and adenosine triphosphate-sensitive potassium channel agonists against inflammation in rat endothelium and vascular smooth muscle in vitro and in vivo.

Anesthesia and analgesia 20040801

Altered gene expression and increased bursting activity of colonic smooth muscle ATP-sensitive K+ channels in experimental colitis.

American journal of physiology. Gastrointestinal and liver physiology 20040701

Effects of bupivacaine enantiomers and ropivacaine on vasorelaxation mediated by adenosine triphosphate-sensitive K(+) channels in the rat aorta.

Anesthesiology 20040701

Spreading dilatation in rat mesenteric arteries associated with calcium-independent endothelial cell hyperpolarization.

The Journal of physiology 20040501

Recent developments in the chemistry of potassium channel activators: the cromakalim analogs.

Current medicinal chemistry 20040501

Endothelial cell proliferation associated with abrupt reduction in shear stress is dependent on reactive oxygen species.

Antioxidants & redox signaling 20040401

Role of ATP-sensitive K+ channels in relaxation of penile resistance arteries.

Urology 20040401

Amplification by hyperoxia of coronary vasodilation induced by propofol.

Anesthesia and analgesia 20040301

Blocking actions of glibenclamide on ATP-sensitive K+ channels in pig urethral myocytes.

The Journal of pharmacy and pharmacology 20040301

Small molecule mitochondrial F1F0 ATPase hydrolase inhibitors as cardioprotective agents. Identification of 4-(N-arylimidazole)-substituted benzopyran derivatives as selective hydrolase inhibitors.

Journal of medicinal chemistry 20040226

Cocaine inhibits cromakalim-activated K+ currents in follicle-enclosed Xenopus oocytes.

Naunyn-Schmiedeberg's archives of pharmacology 20040201

[High throughput screening method of potassium channel regulators].

Yao xue xue bao = Acta pharmaceutica Sinica 20040201

Correlation between spontaneous electrical, calcium and mechanical activity in detrusor smooth muscle of the guinea-pig bladder.

British journal of pharmacology 20040101

1-(2-pyrimidinyl)-piperazine, a buspirone metabolite, modulates bladder function in the anesthetized rat.

Neurourology and urodynamics 20040101

Effects of ouabain on human bronchial muscle in vitro.

Naunyn-Schmiedeberg's archives of pharmacology 20031101

Diazoxide induces delayed pre-conditioning in cultured rat cortical neurons.

Journal of neurochemistry 20031101

ATP-dependent K+ channels in renal ischemia reperfusion injury.

Renal failure 20031101

Shear stress increases expression of a KATP channel in rat and bovine pulmonary vascular endothelial cells.

American journal of physiology. Cell physiology 20031001

Cromakalim inhibits transmitter acetylcholine release in rat trachea by an action on epithelial cells and a diffusible factor.

Naunyn-Schmiedeberg's archives of pharmacology 20031001

Effect of acute hypoxia on ATP-sensitive potassium currents in substantia gelatinosa neurons of juvenile rats.

Pflugers Archiv : European journal of physiology 20030801

The role of K+ channels in vasorelaxation induced by hypoxia and the modulator effects of lidocaine in the rat carotid artery.

Anesthesia and analgesia 20030801

Melatonin inhibits nitrate tolerance in isolated coronary arteries.

British journal of pharmacology 20030801

Differential role of PTK and ERK MAPK in superoxide impairment of K(ATP) and K(Ca) channel cerebrovasodilation.

American journal of physiology. Regulatory, integrative and comparative physiology 20030701

The discovery of a new class of large-conductance Ca2+-activated K+ channel opener targeted for overactive bladder: synthesis and structure-activity relationships of 2-amino-4-azaindoles.

Bioorganic & medicinal chemistry letters 20030616

Role of cyclooxygenase-1 and -2, phospholipase C, and protein kinase C in prostaglandin-mediated gastroprotection.

The Journal of pharmacology and experimental therapeutics 20030601

Mitochondrial K ATP channel activation is important in the antiarrhythmic and cardioprotective effects of non-hypotensive doses of nicorandil and cromakalim during ischemia/reperfusion: a study in an intact anesthetized rabbit model.

Pharmacological research 20030601

Defibrillatory action of glibenclamide is independent from ATP-sensitive K+ channels and free radicals.

Journal of cardiovascular pharmacology 20030601

Differential antivasoconstrictor effects of levcromakalim and rilmakalim on the isolated human mammary artery and saphenous vein.

Journal of pharmacological sciences 20030601

Structure-activity relationship of a novel class of naphthyl amide KATP channel openers.

Bioorganic & medicinal chemistry letters 20030519

Effect of hypoxia on vasodilator responses to S-nitroso-N-acetylpenicillamine and levcromakalim in guinea pig basilar artery.

Naunyn-Schmiedeberg's archives of pharmacology 20030501

Dualistic actions of cromakalim and new potent 2H-1,4-benzoxazine derivatives on the native skeletal muscle K ATP channel.

British journal of pharmacology 20030501

Increased superoxide dismutase and Na+, K+-ATPase activities in aortic strips from potassium-adapted rats: implication for altered vascular reactivity.

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20030501

Potassium channel activators based on the benzopyran substructure: synthesis and activity of the C-8 substituent.

Bioorganic & medicinal chemistry 20030417

Coronary myogenic constriction antagonizes EDHF-mediated dilation: role of KCa channels.

Hypertension (Dallas, Tex. : 1979) 20030401

Mexiletine differentially modulates vasorelaxation mediated by adenosine triphosphate-sensitive K+ channels in aortas from normotensive and hypertensive rats.

Anesthesia and analgesia 20030301

[Analyses of Ca-related ion channel currents and their involvement in Ca mobilization in smooth muscle and endothelial cells].

Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20030301

Differential effects of ascorbate on endothelium-derived hyperpolarizing factor (EDHF)-mediated vasodilatation in the bovine ciliary vascular bed and coronary artery.

British journal of pharmacology 20030301

Functional role of potassium channels in the vasodilating mechanism of levosimendan in porcine isolated coronary artery.

Cardiovascular drugs and therapy 20030301

Contractile responses of the human umbilical artery to KCl and serotonin in Ca-free medium and the effects of levcromakalim.

Life sciences 20030207

In vivo evaluation of the potency and bladder-vascular selectivity of the ATP-sensitive potassium channel openers (-)-cromakalim, ZD6169 and WAY-133537 in rats.

BJU international 20030201

Differential effects of sulphonylureas on the vasodilatory response evoked by K(ATP) channel openers.

Fundamental & clinical pharmacology 20030201

[Effect of levcromakalim and cromakalim on ATP-sensitive K+ channel of pulmonary arterial smooth muscle cells in pulmonary hypertensive rats].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20030201

Inhibitory effects of etomidate and ketamine on adenosine triphosphate-sensitive potassium channel relaxation in canine pulmonary artery.

Anesthesiology 20030101

Effects of ATP-sensitive K+ channel openers and tolterodine on involuntary bladder contractions in a pig model of partial bladder outlet obstruction.

Neurourology and urodynamics 20030101

Inhibition of cromakalim-activated K+ current by ethanol in follicle-enclosed Xenopus oocytes.

Naunyn-Schmiedeberg's archives of pharmacology 20030101

Antiulcer activity of levcromakalim and nicorandil in albino rats: a comparative study.

Polish journal of pharmacology 20030101

Alterations in KATP and KCa channel function in cerebral arteries of insulin-resistant rats.

American journal of physiology. Heart and circulatory physiology 20021201

Ketamine stereoselectively affects vasorelaxation mediated by ATP-sensitive K(+) channels in the rat aorta.

Anesthesiology 20021001

Synthesis and vasorelaxant activity of new 1,4-benzoxazine derivatives potassium channel openers.

Bioorganic & medicinal chemistry 20020801

Effects of chronic treatment with cromakalim and glibenclamide in alloxan-induced diabetic rats.

Pharmacological research 20020801

Molecular modeling and QSAR studies on K(ATP) channel openers of the benzopyran type.

Journal of molecular graphics & modelling 20020801

Protein tyrosine kinase and mitogen-activated protein kinase activation contribute to K(ATP) and K(ca) channel impairment after brain injury.

Brain research 20020712

Potassium channels and human corporeal smooth muscle cell tone: diabetes and relaxation of human corpus cavernosum smooth muscle by adenosine triphosphate sensitive potassium channel openers.

The Journal of urology 20020701

Modified ionic models of cardiac tissue for efficient large scale computations.

Physics in medicine and biology 20020607

Structure-Activity studies for a novel series of tricyclic dihydropyrimidines as K(ATP) channel openers (KCOs).

Bioorganic & medicinal chemistry letters 20020603

The JT-area indicates dispersion of repolarization in dogs with atrioventricular block.

Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing 20020601

Effect of 17beta-estradiol exposure on vasorelaxation induced by K(+) channel openers and Ca(2+) channel blockers.

Pharmacology 20020501

Gene transfer of Cu/Zn SOD to cerebral vessels prevents FPI-induced CBF autoregulatory dysfunction.

American journal of physiology. Heart and circulatory physiology 20020501

Opening of mitochondrial ATP-sensitive potassium channels evokes oxygen radical generation in rabbit heart slices.

Journal of biochemistry 20020501

Effects of K(ATP) channel modulators on acetylcholine release from guinea-pig isolated atria and small intestine.

Naunyn-Schmiedeberg's archives of pharmacology 20020501

Effects of cromakalim and glibenclamide on arteriolar and venular diameters and macromolecular leakage in the microcirculation during ischemia/reperfusion.

Journal of cardiovascular pharmacology 20020301

Characterisation of the effects of potassium channel modulating agents on mouse intestinal smooth muscle.

The Journal of pharmacy and pharmacology 20020301

Vasorelaxant properties of isolated human radial arteries: comparison with internal mammary arteries.

Atherosclerosis 20020201

Hydrogen peroxide is an endothelium-derived hyperpolarizing factor in human mesenteric arteries.

Biochemical and biophysical research communications 20020125

Circumferential stretching of saphenous vein smooth muscle enhances vasoconstrictor responses by Rho kinase-dependent pathways.

Cardiovascular research 20020101

The molecular composition of K(ATP) channels in human pulmonary artery smooth muscle cells and their modulation by growth.

American journal of respiratory cell and molecular biology 20020101

Evidence for the possible involvement of Ca2+ entry blockade in the relaxation by class I antiarrhythmic drugs in the isolated pig coronary smooth muscle.

Naunyn-Schmiedeberg's archives of pharmacology 20020101

Active relaxation of human gallbladder muscle is mediated by ATP-sensitive potassium channels.

Digestion 20020101

Effect of mild hypothermia on nicorandil-induced vasodilation of pial arterioles in cats.

Critical care medicine 20011101

Effects of different types of K+ channel modulators on the spontaneous myogenic contraction of guinea-pig urinary bladder smooth muscle.

Acta physiologica Scandinavica 20011101

Dimethylsulfoxide and ethanol, commonly used diluents, prevent dilation of pial arterioles by openers of K(ATP) ion channels.

European journal of pharmacology 20011026

Endothelin-Induced cyclooxygenase-dependent superoxide generation contributes to K+ channel functional impairment after brain injury.

Journal of neurotrauma 20011001

Identification and properties of a novel intracellular (mitochondrial) ATP-sensitive potassium channel in brain.

The Journal of biological chemistry 20010907

K(ATP) channel opening during ischemia: effects on myocardial noradrenaline release and ventricular arrhythmias.

Journal of cardiovascular pharmacology 20010901

Protein kinase A-dependent and -independent effects of isoproterenol in rat isolated mesenteric artery: interactions with levcromakalim.

The Journal of pharmacology and experimental therapeutics 20010901

Analysis of responses to hAmylin, hCGRP, and hADM in isolated resistance arteries from the mesenteric vascular bed of the rat.

Peptides 20010901

A xanthine-based KMUP-1 with cyclic GMP enhancing and K(+) channels opening activities in rat aortic smooth muscle.

British journal of pharmacology 20010901

Vasopressin induced cyclooxygenase dependent superoxide generation contributes to K(+) channel function impairment after brain injury.

Brain research 20010810

Cibenzoline has an inhibitory effect on vasorelaxation mediated by adenosine triphosphate-sensitive K(+) channels in the rat carotid artery.

Anesthesia and analgesia 20010801

An ATP-sensitive K(+) conductance in dissociated neurones from adult rat intracardiac ganglia.

The Journal of physiology 20010801

Further investigations into the endothelium-dependent hyperpolarizing effects of bradykinin and substance P in porcine coronary artery.

British journal of pharmacology 20010801

Comparison of the inhibitory effects of cromakalim and pinacidil (potassium channel openers) with those of oxybutynin on stimulated guinea pig and rabbit detrusor muscle strips.

Archives of gynecology and obstetrics 20010801

Influence of ATP-sensitive K+ channel modulation on the mechanical properties of diabetic myocardium.

Endocrine research 20010801

Restoration of vasodilation and CBF autoregulation by genistein in rat pial artery after brain injury.

American journal of physiology. Heart and circulatory physiology 20010701

The effects of flecainide on ATP-sensitive K(+) channels in pig urethral myocytes.

British journal of pharmacology 20010701

Mild alkalinization and acidification differentially modify the effects of lidocaine or mexiletine on vasorelaxation mediated by ATP-sensitive K+ channels.

Anesthesiology 20010701

Hemodynamic effects of levcromakalim in neonatal porcine pulmonary hypertension.

Biology of the neonate 20010701

K(ATP) channels predominantly regulate conduit vessel tone in normoxic cat pulmonary arteries in vivo.

European journal of pharmacology 20010622

Pharmacologic characterization of BMS-191095, a mitochondrial K(ATP) opener with no peripheral vasodilator or cardiac action potential shortening activity.

The Journal of pharmacology and experimental therapeutics 20010601

Vasopressin-induced protein kinase C-dependent superoxide generation contributes to atp-sensitive potassium channel but not calcium-sensitive potassium channel function impairment after brain injury.

Stroke 20010601

Endothelium-dependent desensitization to angiotensin II in rabbit aorta: the mechanisms involved.

Canadian journal of physiology and pharmacology 20010601

The effect of pretreatment with ischaemic preconditioning or cromakalim on perfusion in skeletal muscle during ischaemia-reperfusion injury.

International angiology : a journal of the International Union of Angiology 20010601

Low levels of K(ATP) channel activation decrease excitability and contractility of urinary bladder.

American journal of physiology. Regulatory, integrative and comparative physiology 20010501

Dual action of ZD6169, a novel K(+) channel opener, on ATP-sensitive K(+) channels in pig urethral myocytes.

British journal of pharmacology 20010501

Evidence for a K(ATP) ion channel link in the inhibition of hypercapnic dilation of pial arterioles by 7-nitroindazole and tetrodotoxin.

European journal of pharmacology 20010413

[Role of salbutamol in inducing apoptosis of cultured human airway smooth muscle cells].

Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20010401

The role of K+ATP channels in the control of pre- and post-ischemic left ventricular developed pressure in septic rat hearts.

Canadian journal of physiology and pharmacology 20010301

Peroxynitrite reduces vasodilatory responses to reduced intravascular pressure, calcitonin gene-related peptide, and cromakalim in isolated middle cerebral arteries.

Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20010301

Salt-induced hypertension in rats alters the response of isolated aortic rings to cromakalim.

The West Indian medical journal 20010301

Effects of K+ channel openers on I K(ATP) of human atrial myocytes at physiological temperatures.

Naunyn-Schmiedeberg's archives of pharmacology 20010201

Impaired beta-adrenergic hyperpolarization in arteries from prehypertensive spontaneously hypertensive rats.

Hypertension (Dallas, Tex. : 1979) 20010201

N-Acyl-1,2,3,4a,5,10b-hexahydro-[1]benzopyrano-[3,4-b][1,4]oxazine-9-carbonitriles as bladder-selective potassium channel openers.

Bioorganic & medicinal chemistry 20010201

Intrahippocampal infusions of k-atp channel modulators influence spontaneous alternation performance: relationships to acetylcholine release in the hippocampus.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20010115

Role of mitochondrial and sarcolemmal K(ATP) channels in ischemic preconditioning of the canine heart.

American journal of physiology. Heart and circulatory physiology 20010101

The role of oxygen-derived free radicals in augmented relaxations to levcromakalim in the aorta from hypertensive rats.

Japanese journal of pharmacology 20010101

Role of NO pathway, calcium and potassium channels in the peripheral pulmonary vascular tone in dogs.

The European respiratory journal 20010101

A simple method to investigate the inhibitory effects of drugs on gastric emptying in the mouse in vivo.

Journal of pharmacological and toxicological methods 20010101

Fluorescence-based functional assay for sarcolemmal ATP-sensitive potassium channel activation in cultured neonatal rat ventricular myocytes.

Journal of pharmacological and toxicological methods 20010101

Role of inwardly rectifying K(+) channels in K(+)-induced cerebral vasodilatation in vivo.

American journal of physiology. Heart and circulatory physiology 20001201

Involvement of ATP-sensitive potassium channels in a model of a delayed vascular hyporeactivity induced by lipopolysaccharide in rats.

British journal of pharmacology 19990701

Arterial function in nitric oxide-deficient hypertension: influence of long-term angiotensin II receptor antagonism.

Cardiovascular research 19990601

Genomic organization, chromosomal localization, tissue distribution, and biophysical characterization of a novel mammalian Shaker-related voltage-gated potassium channel, Kv1.7.

The Journal of biological chemistry 19980306

Analysis of relaxation and repolarization mechanisms of nicorandil in rat mesenteric artery.

British journal of pharmacology 19961201

A family of sulfonylurea receptors determines the pharmacological properties of ATP-sensitive K+ channels.

Neuron 19960501

K+ channel openers delay intestinal transit and have antidiarrheal activity.

European journal of pharmacology 19951212

Cellular localization of the inhibitory action of relaxin against uterine spasm.

British journal of pharmacology 19951201

Effect of four potassium channel agonists on bupivacaine-induced toxicity in mice.

Life sciences 19950101

Pharmacological characterization of five cloned voltage-gated K+ channels, types Kv1.1, 1.2, 1.3, 1.5, and 3.1, stably expressed in mammalian cell lines.

Molecular pharmacology 19940601

Effects of potassium channel modulation during global ischaemia in isolated rat heart with and without cardioplegia.

Cardiovascular research 19921101

Molecular mechanism of action of nicorandil.

Journal of cardiovascular pharmacology 19920101

Effects of NG-nitro-L-arginine methyl ester on vasodilator responses to adrenaline or BRL 38227 in conscious rats.

British journal of pharmacology 19911101

Effects of cromakalim and pinacidil on large epicardial and small coronary arteries in conscious dogs.

The Journal of pharmacology and experimental therapeutics 19901101

Suppression of repolarization-related arrhythmias in vitro and in vivo by low-dose potassium channel activators.

Circulation 19901001

Preclinical pharmacology of Ro 31-6930, a new potassium channel opener.

Journal of cardiovascular pharmacology 19900201

Effects of pinacidil and cromakalim (BRL 34915) on bladder function in rats with detrusor instability.

The Journal of urology 19891001

The relaxant action of BRL 34915 in rat uterus.

British journal of pharmacology 19870801