Synthesis and structure-activity relationship studies in serotonin 5-HT(1A) receptor agonists based on fused pyrrolidone scaffolds.

European journal of medicinal chemistry 20130501

Inhibitory effects of benzodiazepines on the adenosine A(2B) receptor mediated secretion of interleukin-8 in human mast cells.

European journal of pharmacology 20130130

Adenosine A2A receptor modulates vascular response in soluble epoxide hydrolase-null mice through CYP-epoxygenases and PPARγ.

American journal of physiology. Regulatory, integrative and comparative physiology 20130101

Downregulation of A(1) and A(2B) adenosine receptors in human trisomy 21 mesenchymal cells from first-trimester chorionic villi.

Biochimica et biophysica acta 20121101

Structural sweet spot for A1 adenosine receptor activation by truncated (N)-methanocarba nucleosides: receptor docking and potent anticonvulsant activity.

Journal of medicinal chemistry 20120927

Adenosine signaling promotes regeneration of pancreatic β cells in vivo.

Cell metabolism 20120606

The A2B adenosine receptor modulates pulmonary hypertension associated with interstitial lung disease.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120601

Optimization of adenosine 5'-carboxamide derivatives as adenosine receptor agonists using structure-based ligand design and fragment screening.

Journal of medicinal chemistry 20120510

Loss of adenosine A2B receptor mediated relaxant responses in the aged female rat bladder; effects of dietary phytoestrogens.

Naunyn-Schmiedeberg's archives of pharmacology 20120501

Opposing effects of ATP and adenosine on barrier function of rat coronary microvasculature.

Journal of molecular and cellular cardiology 20120501

3-aryl-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one: a novel template for the design of highly selective A₂B adenosine receptor antagonists.

Journal of medicinal chemistry 20120223

The role of mechanical forces and adenosine in the regulation of intestinal enterochromaffin cell serotonin secretion.

American journal of physiology. Gastrointestinal and liver physiology 20120201

The effect of adenosine on pro-inflammatory cytokine production by porcine T cells.

Veterinary immunology and immunopathology 20120115

Evaluation of molecular modeling of agonist binding in light of the crystallographic structure of an agonist-bound A₂A adenosine receptor.

Journal of medicinal chemistry 20120112

Enhanced IL-6 transcriptional response to adenosine receptor ligands in horses with lower airway inflammation.

Equine veterinary journal 20120101

Adenosine promotes alternative macrophage activation via A2A and A2B receptors.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20120101

Adora2b adenosine receptor engagement enhances regulatory T cell abundance during endotoxin-induced pulmonary inflammation.

PloS one 20120101

Adenosine reduces cell surface expression of toll-like receptor 4 and inflammation in response to lipopolysaccharide and matrix products.

Journal of cardiovascular translational research 20111201

Pharmacological characterization of adenosine receptors on isolated human bronchi.

American journal of respiratory cell and molecular biology 20111201

Purinergic regulation of high-glucose-induced caspase-1 activation in the rat retinal Müller cell line rMC-1.

American journal of physiology. Cell physiology 20111101

Allosteric interactions across native adenosine-A3 receptor homodimers: quantification using single-cell ligand-binding kinetics.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20111001

Regulation of innate immunity by the nucleotide pathway in children with idiopathic nephrotic syndrome.

Clinical and experimental immunology 20111001

Reciprocal modulation of anti-IgE induced histamine release from human mast cells by A₁ and A(2B) adenosine receptors.

British journal of pharmacology 20110901

Adenosine receptor subtype expression and activation influence the differentiation of mesenchymal stem cells to osteoblasts and adipocytes.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20110901

Synthesis and biological activity of tricyclic cycloalkylimidazo-, pyrimido- and diazepinopurinediones.

European journal of medicinal chemistry 20110901

Adenosine activation of A(2B) receptor(s) is essential for stimulated epithelial ciliary motility and clearance.

American journal of physiology. Lung cellular and molecular physiology 20110801

5'-(N-ethylcarboxamido) adenosine improves angiogenesis in transplanted human ovarian tissue.

Fertility and sterility 20110630

Thermostabilisation of an agonist-bound conformation of the human adenosine A(2A) receptor.

Journal of molecular biology 20110610

Agonist-bound adenosine A2A receptor structures reveal common features of GPCR activation.

Nature 20110518

GPCR structure and activation: an essential role for the first extracellular loop in activating the adenosine A2B receptor.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20110201

Links between insulin resistance, adenosine A2B receptors, and inflammatory markers in mice and humans.

Diabetes 20110201

Pyrimidine derivatives as potent and selective A3 adenosine receptor antagonists.

Journal of medicinal chemistry 20110127

Effect of fluoxetine or adenosine receptor NECA agonist on G-proteins of C6 glioma cells or NK immunocytes.

Neuro endocrinology letters 20110101

Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: design, synthesis, and structure-activity relationships.

Bioorganic & medicinal chemistry 20101101

Both A2a and A2b adenosine receptors at reperfusion are necessary to reduce infarct size in mouse hearts.

American journal of physiology. Heart and circulatory physiology 20101001

Contraction-induced secretion of VEGF from skeletal muscle cells is mediated by adenosine.

American journal of physiology. Heart and circulatory physiology 20100901

Inhibition of neutrophil-mediated production of reactive oxygen species (ROS) by endothelial cells is not impaired in anti-neutrophil cytoplasmic autoantibodies (ANCA)-associated vasculitis patients.

Clinical and experimental immunology 20100801

Multivalent dendrimeric and monomeric adenosine agonists attenuate cell death in HL-1 mouse cardiomyocytes expressing the A(3) receptor.

Biochemical pharmacology 20100715

The critical role of intracellular zinc in adenosine A(2) receptor activation induced cardioprotection against reperfusion injury.

Journal of molecular and cellular cardiology 20100701

Involvement of Cx43 phosphorylation in 5'-N-ethylcarboxamide-induced migration and proliferation of mouse embryonic stem cells.

Journal of cellular physiology 20100701

Involvement of A1 adenosine receptors in altered vascular responses and inflammation in an allergic mouse model of asthma.

American journal of physiology. Heart and circulatory physiology 20100701

Modulation by salt intake of the vascular response mediated through adenosine A(2A) receptor: role of CYP epoxygenase and soluble epoxide hydrolase.

American journal of physiology. Regulatory, integrative and comparative physiology 20100701

Adenosine A(3) receptor stimulation induces protection of skeletal muscle from eccentric exercise-mediated injury.

American journal of physiology. Regulatory, integrative and comparative physiology 20100701

Fibroblast-specific expression of AC6 enhances beta-adrenergic and prostacyclin signaling and blunts bleomycin-induced pulmonary fibrosis.

American journal of physiology. Lung cellular and molecular physiology 20100601

Novel N2-substituted pyrazolo[3,4-d]pyrimidine adenosine A3 receptor antagonists: inhibition of A3-mediated human glioblastoma cell proliferation.

Journal of medicinal chemistry 20100527

Oxidative/nitrosative stress selectively altered A(2B) adenosine receptors in chronic obstructive pulmonary disease.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20100401

Stimulation of adenosine A(2B) receptors induces interleukin-6 secretion in cardiac fibroblasts via the PKC-delta-P38 signalling pathway.

British journal of pharmacology 20100401

Antagonist selective modulation of adenosine A1 and A3 receptor pharmacology by the food dye Brilliant Black BN: evidence for allosteric interactions.

Molecular pharmacology 20100401

A new role for the A2b adenosine receptor in regulating platelet function.

Journal of thrombosis and haemostasis : JTH 20100401

Novel 8-(furan-2-yl)-3-substituted thiazolo [5,4-e][1,2,4] triazolo[1,5-c] pyrimidine-2(3H)-thione derivatives as potential adenosine A(2A) receptor antagonists.

Bioorganic & medicinal chemistry 20100401

A volume regulatory response can be triggered by nucleosides in human erythrocytes, a perfect osmometer no longer.

The Journal of biological chemistry 20100226

Adenosine mediated desensitization of cAMP signaling enhances T-cell responses.

European journal of immunology 20100201

Synthesis and evaluation of two series of 4'-aza-carbocyclic nucleosides as adenosine A2A receptor agonists.

Bioorganic & medicinal chemistry letters 20100201

Influence of fluorophore and linker composition on the pharmacology of fluorescent adenosine A1 receptor ligands.

British journal of pharmacology 20100201

2-Dialkynyl derivatives of (N)-methanocarba nucleosides: 'Clickable' A(3) adenosine receptor-selective agonists.

Bioorganic & medicinal chemistry 20100115

Pharmacological validation of a telemetric model for the measurement of bronchoconstriction in conscious rats.

Journal of pharmacological and toxicological methods 20100101

Elevated cAMP opposes (TNF-alpha)-induced loss in the barrier integrity of corneal endothelium.

Molecular vision 20100101

Theophylline inhibits the differentiation of human monocyte into dendritic cell potentially via adenosine receptor antagonism.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20091201

Purinergic modulation in the development of the rat uncrossed retinotectal pathway.

Neuroscience 20091110

Adenosine A2A and A2B receptors work in concert to induce a strong protection against reperfusion injury in rat hearts.

Journal of molecular and cellular cardiology 20091101

Absence of adenosine-mediated aortic relaxation in A(2A) adenosine receptor knockout mice.

American journal of physiology. Heart and circulatory physiology 20091101

Cholesterol-dependent regulation of adenosine A(2A) receptor-mediated anion secretion in colon epithelial cells.

Experimental cell research 20091015

Adenosine-evoked hyperpolarization of retinal ganglion cells is mediated by G-protein-coupled inwardly rectifying K+ and small conductance Ca2+-activated K+ channel activation.

The Journal of neuroscience : the official journal of the Society for Neuroscience 20090909

Differential regulation of HIF-1alpha isoforms in murine macrophages by TLR4 and adenosine A(2A) receptor agonists.

Journal of leukocyte biology 20090901

1-alkyl-8-(piperazine-1-sulfonyl)phenylxanthines: development and characterization of adenosine A2B receptor antagonists and a new radioligand with subnanomolar affinity and subtype specificity.

Journal of medicinal chemistry 20090709

Synthesis of hybrid analogues of caffeine and eudistomin D and its affinity for adenosine receptors.

Bioorganic & medicinal chemistry 20090701

Intranasal administration of NECA can induce both anti-inflammatory and pro-inflammatory effects in BALB/c mice: evidence for A 2A receptor sub-type mediation of NECA-induced anti-inflammatory effects.

Pulmonary pharmacology & therapeutics 20090601

5'-N-ethylcarboxamide induces IL-6 expression via MAPKs and NF-kappaB activation through Akt, Ca(2+)/PKC, cAMP signaling pathways in mouse embryonic stem cells.

Journal of cellular physiology 20090601

Adenosine signaling mediates SUMO-1 modification of IkappaBalpha during hypoxia and reoxygenation.

The Journal of biological chemistry 20090515

Vascular endothelial growth factors synthesized by human lung mast cells exert angiogenic effects.

The Journal of allergy and clinical immunology 20090501

Regulation of cardiac fibroblast collagen synthesis by adenosine: roles for Epac and PI3K.

American journal of physiology. Cell physiology 20090501

Novel 2- and 4-substituted 1H-imidazo[4,5-c]quinolin-4-amine derivatives as allosteric modulators of the A3 adenosine receptor.

Journal of medicinal chemistry 20090409

High-salt diet enhances mouse aortic relaxation through adenosine A2A receptor via CYP epoxygenases.

American journal of physiology. Regulatory, integrative and comparative physiology 20090301

Involvement of NO and KATP channel in adenosine A2B receptors induced cardiovascular regulation in the posterior hypothalamus of rats.

Journal of cardiovascular pharmacology 20090201

Adenosine induces loss of actin stress fibers and inhibits contraction in hepatic stellate cells via Rho inhibition.

Hepatology (Baltimore, Md.) 20090101

In vitro induction of T cells that are resistant to A2 adenosine receptor-mediated immunosuppression.

British journal of pharmacology 20090101

Contribution of NO, ATP-sensitive K+ channels and prostaglandins to adenosine receptor agonists-induced relaxation of the rat tail artery.

Pharmacological reports : PR 20090101

The A(2B)-D(2) receptor interaction that controls carotid body catecholamines release locates between the last two steps of hypoxic transduction cascade.

Advances in experimental medicine and biology 20090101

An antagonistic interaction between A2B adenosine and D2 dopamine receptors modulates the function of rat carotid body chemoreceptor cells.

Journal of neurochemistry 20081201

Modulation of insulin release by adenosine A1 receptor agonists and antagonists in INS-1 cells: the possible contribution of 86Rb+ efflux and 45Ca2+ uptake.

Cell biochemistry and function 20081201

cis-4-(Piperazin-1-yl)-5,6,7a,8,9,10,11,11a-octahydrobenzofuro[2,3-h]quinazolin-2-amine (A-987306), a new histamine H4R antagonist that blocks pain responses against carrageenan-induced hyperalgesia.

Journal of medicinal chemistry 20081127

Role of CYP epoxygenases in A2A AR-mediated relaxation using A2A AR-null and wild-type mice.

American journal of physiology. Heart and circulatory physiology 20081101

A new chemical tool (C0036E08) supports the role of adenosine A(2B) receptors in mediating human mast cell activation.

Biochemical pharmacology 20081001

Selective inhibitory effect of adenosine A1 receptor agonists on the proliferation of human tumor cell lines.

Iranian biomedical journal 20081001

Adenosine A(2A) receptor dynamics studied with the novel fluorescent agonist Alexa488-APEC.

European journal of pharmacology 20080820

2-Amino-6-furan-2-yl-4-substituted nicotinonitriles as A2A adenosine receptor antagonists.

Journal of medicinal chemistry 20080814

N6-1,3-diphenylurea derivatives of 2-phenyl-9-benzyladenines and 8-azaadenines: synthesis and biological evaluation as allosteric modulators of A2A adenosine receptors.

European journal of medicinal chemistry 20080801

A2B adenosine receptors regulate the mucus clearance component of the lung's innate defense system.

American journal of respiratory cell and molecular biology 20080801

Identification of a potent, selective, and orally active leukotriene a4 hydrolase inhibitor with anti-inflammatory activity.

Journal of medicinal chemistry 20080724

Adenosine induces airway hyperresponsiveness through activation of A3 receptors on mast cells.

The Journal of allergy and clinical immunology 20080701

Adenosine receptor agonists attenuate the development of diazepam withdrawal-induced sensitization in mice.

European journal of pharmacology 20080624

Effects of IL-4 and IL-13 on adenosine receptor expression and responsiveness of the human mast cell line 1.

International immunopharmacology 20080601

Modulation of murine dendritic cell function by adenine nucleotides and adenosine: involvement of the A(2B) receptor.

European journal of immunology 20080601

Local stimulation of the adenosine A2B receptors induces an increased release of IL-6 in mouse striatum: an in vivo microdialysis study.

Journal of neurochemistry 20080501

Up-regulation of A 2B adenosine receptor in A 2A adenosine receptor knockout mouse coronary artery.

Journal of molecular and cellular cardiology 20080501

Design of (N)-methanocarba adenosine 5'-uronamides as species-independent A3 receptor-selective agonists.

Bioorganic & medicinal chemistry letters 20080501

Probing distal regions of the A2B adenosine receptor by quantitative structure-activity relationship modeling of known and novel agonists.

Journal of medicinal chemistry 20080410

Synthesis of eudistomin D analogues and its effects on adenosine receptors.

Bioorganic & medicinal chemistry 20080401

Derivatives of 4-amino-6-hydroxy-2-mercaptopyrimidine as novel, potent, and selective A3 adenosine receptor antagonists.

Journal of medicinal chemistry 20080327

[Advances in the study of A2B adenosine receptor antagonists].

Yao xue xue bao = Acta pharmaceutica Sinica 20080301

Adenosine A2A receptor agonists inhibit lipopolysaccharide-induced production of tumor necrosis factor-alpha by equine monocytes.

Veterinary immunology and immunopathology 20080115

Involvement of adenosine receptor agonists on the development of hypersensitivity to acute dose of morphine during morphine withdrawal period.

Pharmacological reports : PR 20080101

Flexible modulation of agonist efficacy at the human A3 adenosine receptor by the imidazoquinoline allosteric enhancer LUF6000.

BMC pharmacology 20080101

Structure-activity relationships of adenosines with heterocyclic N6-substituents.

Bioorganic & medicinal chemistry letters 20071215

In vivo adenosine A(2B) receptor desensitization in guinea-pig airway smooth muscle: implications for asthma.

European journal of pharmacology 20071201

5-amino-2-phenyl[1,2,3]triazolo[1,2-a][1,2,4]benzotriazin-1-one: a versatile scaffold to obtain potent and selective A3 adenosine receptor antagonists.

Journal of medicinal chemistry 20071115

Adenosine A1 but not A2a receptor agonist reduces hyperalgesia caused by a surgical incision in rats: a pertussis toxin-sensitive G protein-dependent process.

Anesthesiology 20071101

Adenosine deaminase 1 and concentrative nucleoside transporters 2 and 3 regulate adenosine on the apical surface of human airway epithelia: implications for inflammatory lung diseases.

Biochemistry 20070911

Protein kinase C protects preconditioned rabbit hearts by increasing sensitivity of adenosine A2b-dependent signaling during early reperfusion.

Journal of molecular and cellular cardiology 20070901

Pharmacologic characterization of novel adenosine A2A receptor agonists in equine neutrophils.

American journal of veterinary research 20070901

A(2b) receptor mediates adenosine inhibition of taurine efflux from pituicytes.

Biology of the cell 20070801

Adenosine receptor activation ameliorates type 1 diabetes.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070801

Involvement of guanylate cyclase in the cardiovascular response induced by adenosine A2B receptor stimulation in the posterior hypothalamus of the anesthetized rats.

Autonomic neuroscience : basic & clinical 20070731

Rapid stimulation of presynaptic serotonin transport by A(3) adenosine receptors.

The Journal of pharmacology and experimental therapeutics 20070701

Involvement of A1 adenosine receptors and neural pathways in adenosine-induced bronchoconstriction in mice.

American journal of physiology. Lung cellular and molecular physiology 20070701

ATP modulates the release of noradrenaline through two different prejunctional receptors on the adrenergic nerves of rat prostate.

Clinical and experimental pharmacology & physiology 20070701

Effects of stimulation of adenosine A2A receptors on lipopolysaccharide-induced production of reactive oxygen species by equine neutrophils.

American journal of veterinary research 20070601

Synthesis of hybrid molecules of caffeine and eudistomin D and its effects on adenosine receptors.

Bioorganic & medicinal chemistry 20070501

Adenosine is not a direct GHSR agonist--artificial cross-talk between GHSR and adenosine receptor pathways.

Acta physiologica (Oxford, England) 20070501

Cross-regulation of carbon monoxide and the adenosine A2a receptor in macrophages.

Journal of immunology (Baltimore, Md. : 1950) 20070501

Structure-activity relationships of 2,N(6),5'-substituted adenosine derivatives with potent activity at the A2B adenosine receptor.

Journal of medicinal chemistry 20070419

N(6)-[(hetero)aryl/(cyclo)alkyl-carbamoyl-methoxy-phenyl]-(2-chloro)-5'-N-ethylcarboxamido-adenosines: the first example of adenosine-related structures with potent agonist activity at the human A(2B) adenosine receptor.

Bioorganic & medicinal chemistry 20070401

Adenosine opposes thrombin-induced inhibition of intercellular calcium wave in corneal endothelial cells.

Investigative ophthalmology & visual science 20070401

Effect of a specific and selective A(2B) adenosine receptor antagonist on adenosine agonist AMP and allergen-induced airway responsiveness and cellular influx in a mouse model of asthma.

The Journal of pharmacology and experimental therapeutics 20070301

New fluorescent adenosine A1-receptor agonists that allow quantification of ligand-receptor interactions in microdomains of single living cells.

Journal of medicinal chemistry 20070222

Role of adenosine receptors in the regulation of angiogenic factors and neovascularization in hypoxia.

The Journal of pharmacology and experimental therapeutics 20070201

Synthesis and biological evaluation of novel 1-deoxy-1-[6-[((hetero)arylcarbonyl)hydrazino]- 9H-purin-9-yl]-N-ethyl-beta-D-ribofuranuronamide derivatives as useful templates for the development of A2B adenosine receptor agonists.

Journal of medicinal chemistry 20070125

Structure-activity relationship study of prion inhibition by 2-aminopyridine-3,5-dicarbonitrile-based compounds: parallel synthesis, bioactivity, and in vitro pharmacokinetics.

Journal of medicinal chemistry 20070111

Evidence for the involvement of nitric oxide in A2B receptor-mediated vasorelaxation of mouse aorta.

American journal of physiology. Heart and circulatory physiology 20070101

The thyroid disruptor 1,1,1-trichloro-2,2-bis(p-chlorophenyl)-ethane appears to be an uncompetitive inverse agonist for the thyrotropin receptor.

The Journal of pharmacology and experimental therapeutics 20070101

Intratumoral lymphatic vessels and VEGF-C expression are predictive factors of lymph node relapse in T1-T4 N0 laryngopharyngeal squamous cell carcinoma.

Annals of surgical oncology 20070101

Human micro- and macrovessel-derived endothelial cells: a comparative study on the effects of adrenaline and a selective adenosine A2-type receptor agonist under normoxic and hypoxic conditions.

Pharmacological reports : PR 20070101

Regulation of pharmacology by hetero-oligomerization between A1 adenosine receptor and P2Y2 receptor.

Biochemical and biophysical research communications 20061215

Loss of vascular adenosine A1 receptors with age in the rat heart.

Vascular pharmacology 20061201

The impact of adenosine and A(2B) receptors on glucose homoeostasis.

The Journal of pharmacy and pharmacology 20061201

Expression of adenosine receptors in cardiac fibroblasts as a function of insulin and glucose level.

Archives of biochemistry and biophysics 20061101

Adenosine A1 receptors mediate mobilization of calcium in human bronchial smooth muscle cells.

American journal of respiratory cell and molecular biology 20061001

Corpus cavernosum from men with vasculogenic impotence is partially resistant to adenosine relaxation due to endothelial A(2B) receptor dysfunction.

The Journal of pharmacology and experimental therapeutics 20061001

Cross-talk between G(s)- and G(q)-coupled pathways in regulation of interleukin-4 by A(2B) adenosine receptors in human mast cells.

Molecular pharmacology 20060801

Real-time and high throughput monitoring of cAMP in live cells using a fluorescent membrane potential-sensitive dye.

Assay and drug development technologies 20060801

NECA at reperfusion limits infarction and inhibits formation of the mitochondrial permeability transition pore by activating p70S6 kinase.

Basic research in cardiology 20060701

Orthogonal activation of the reengineered A3 adenosine receptor (neoceptor) using tailored nucleoside agonists.

Journal of medicinal chemistry 20060504

N6-ethyl-2-alkynyl NECAs, selective human A3 adenosine receptor agonists.

Bioorganic & medicinal chemistry letters 20060501

Postconditioning protects rabbit hearts through a protein kinase C-adenosine A2b receptor cascade.

Cardiovascular research 20060501

Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Characterization of adenosine receptors in the human bladder carcinoma T24 cell line.

European journal of pharmacology 20060424

Astrocytes promote myelination in response to electrical impulses.

Neuron 20060316

Moderate hypoxia induces xanthine oxidoreductase activity in arterial endothelial cells.

Free radical biology & medicine 20060315

Role of the second transmembrane domain of rat adenosine A1 receptor in ligand-receptor interaction.

Biochemical pharmacology 20060314

Solid phase synthesis and antiprotozoal evaluation of di- and trisubstituted 5'-carboxamidoadenosine analogues.

Bioorganic & medicinal chemistry 20060301

A membrane-permeable peptide containing the last 21 residues of the G alpha(s) carboxyl terminus inhibits G(s)-coupled receptor signaling in intact cells: correlations between peptide structure and biological activity.

Molecular pharmacology 20060301

Binding of the viral immunogenic octapeptide VSV8 to native glucose-regulated protein Grp94 (gp96) and its inhibition by the physiological ligands ATP and Ca2+.

The FEBS journal 20060201

Purinergic substances promote murine keratinocyte proliferation and enhance impaired wound healing in mice.

Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20060101

2-(Benzimidazol-2-yl)quinoxalines: a novel class of selective antagonists at human A(1) and A(3) adenosine receptors designed by 3D database searching.

Journal of medicinal chemistry 20051229

Pharmacological characterization of novel adenosine ligands in recombinant and native human A2B receptors.

Biochemical pharmacology 20051125

Influence of adenosine receptor agonists on benzodiazepine withdrawal signs in mice.

European journal of pharmacology 20051031

Neuroprotective effect of paeoniflorin on cerebral ischemic rat by activating adenosine A1 receptor in a manner different from its classical agonists.

British journal of pharmacology 20051001

Caffeine intake induces an alteration in human neutrophil A2A adenosine receptors.

Cellular and molecular life sciences : CMLS 20051001

Gs protein-coupled adenosine receptor signaling and lytic function of activated NK cells.

Journal of immunology (Baltimore, Md. : 1950) 20051001

Mast cell involvement in the adenosine mediated airway hyper-reactivity in a murine model of ovalbumin-induced lung inflammation.

British journal of pharmacology 20050801

Adenosine signaling promotes neuronal, catecholaminergic differentiation of primary neural crest cells and CNS-derived CAD cells.

Molecular and cellular neurosciences 20050701

Involvement of p38-mitogen-activated protein kinase in adenosine receptor-mediated relaxation of coronary artery.

American journal of physiology. Heart and circulatory physiology 20050601

Expression, pharmacological profile, and functional coupling of A2B receptors in a recombinant system and in peripheral blood cells using a novel selective antagonist radioligand, [3H]MRE 2029-F20.

Molecular pharmacology 20050601

A2B adenosine receptor mediates human chorionic vasoconstriction and signals through arachidonic acid cascade.

American journal of physiology. Heart and circulatory physiology 20050501

Human breast cancer cell line MDA-MB-231 expresses endogenous A2B adenosine receptors mediating a Ca2+ signal.

British journal of pharmacology 20050501

Involvement of mast cells in adenosine-mediated bronchoconstriction and inflammation in an allergic mouse model.

The Journal of pharmacology and experimental therapeutics 20050401

Adenosine agonist regulation of outward active transport of fluorescein across retinal pigment epithelium in rabbits.

Experimental eye research 20050401

Binding thermodynamics as a tool to investigate the mechanisms of drug-receptor interactions: thermodynamics of cytoplasmic steroid/nuclear receptors in comparison with membrane receptors.

Journal of medicinal chemistry 20050324

The role of adenosine A2A and A2B receptors in the regulation of TNF-alpha production by human monocytes.

Biochemical pharmacology 20050315

Synthesis, biological evaluation, and molecular modeling of ribose-modified adenosine analogues as adenosine receptor agonists.

Journal of medicinal chemistry 20050310

Role of A1 adenosine receptors in regulation of vascular tone.

American journal of physiology. Heart and circulatory physiology 20050301

Adenosine receptor mediates nicotine-induced antinociception in formalin test.

Pharmacological research 20050301

Different modulation of inhibitory and stimulatory pathways mediated by adenosine after chronic in vivo agonist exposure.

Brain research 20050121

A2B adenosine receptor activity is reduced in neutrophils from patients with systemic sclerosis.

Arthritis research & therapy 20050101

Modulation of cytokine release by purine receptors in patients with rheumatoid arthritis.

Clinical and experimental rheumatology 20050101

Participation of adenosine system in the ketamine-induced motor activity in mice.

Pharmacological reports : PR 20050101

New 8-substituted xanthiene derivatives as potent bronchodilators.

Farmaco (Societa chimica italiana : 1989) 20050101

Ring opening reactions: synthesis of AICAR analogs as potential antimetabolite agents.

Nucleosides, nucleotides & nucleic acids 20050101

Functional effects of enhancing or silencing adenosine A2b receptors in cardiac fibroblasts.

American journal of physiology. Heart and circulatory physiology 20041201

Regulation of A2B adenosine receptor functioning by tumour necrosis factor a in human astroglial cells.

Journal of neurochemistry 20041201

2-Substituted adenosine derivatives: affinity and efficacy at four subtypes of human adenosine receptors.

Biochemical pharmacology 20041115

Adenosine receptors involved in modulation of noradrenaline release in isolated rat tail artery.

European journal of pharmacology 20041103

Coupling of the human A1 adenosine receptor to different heterotrimeric G proteins: evidence for agonist-specific G protein activation.

British journal of pharmacology 20041101

Synthesis and biological evaluation of novel N6-[4-(substituted)sulfonamidophenylcarbamoyl]adenosine-5'-uronamides as A3 adenosine receptor agonists.

Journal of medicinal chemistry 20041021

Influence of the combined treatment of LY 300164 (an AMPA/kainate receptor antagonist) with adenosine receptor agonists on the electroconvulsive threshold in mice.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20041001

Negative chronotropic response to adenosine receptor stimulation in rat right atria after run training.

Clinical and experimental pharmacology & physiology 20041001

Purine modulation of cytokine release during diuretic therapy of rheumatoid arthritis.

Nucleosides, nucleotides & nucleic acids 20041001

ATP-sensitive potassium channels and endogenous adenosine are involved in spinal antinociception produced by locus coeruleus stimulation.

The International journal of neuroscience 20040801

Synthesis and biological activity of new potential agonists for the human adenosine A2A receptor.

Journal of medicinal chemistry 20040729

[3H]OSIP339391, a selective, novel, and high affinity antagonist radioligand for adenosine A2B receptors.

Biochemical pharmacology 20040715

New, non-adenosine, high-potency agonists for the human adenosine A2B receptor with an improved selectivity profile compared to the reference agonist N-ethylcarboxamidoadenosine.

Journal of medicinal chemistry 20040715

1,2,4-triazolo[4,3-a]quinoxalin-1-one moiety as an attractive scaffold to develop new potent and selective human A3 adenosine receptor antagonists: synthesis, pharmacological, and ligand-receptor modeling studies.

Journal of medicinal chemistry 20040701

Adenosine-activated mast cells induce IgE synthesis by B lymphocytes: an A2B-mediated process involving Th2 cytokines IL-4 and IL-13 with implications for asthma.

Journal of immunology (Baltimore, Md. : 1950) 20040615

Comparative analysis of putative agonist-binding modes in the human A1 adenosine receptor.

Chembiochem : a European journal of chemical biology 20040607

Adenosine receptor, protein kinase G, and p38 mitogen-activated protein kinase-dependent up-regulation of serotonin transporters involves both transporter trafficking and activation.

Molecular pharmacology 20040601

An IgM class anti-neutrophil cytoplasm antibody inhibits neutrophil adhesion and apoptosis via a Syk dependent signaling cascade.

Molecular immunology 20040601

Characterization of glycine N-methyltransferase from rabbit liver.

Biochemistry and cell biology = Biochimie et biologie cellulaire 20040601

Development of a sensitive and HTS-compatible reporter gene assay for functional analysis of human adenosine A2a receptors in CHO-K1 cells.

Assay and drug development technologies 20040601

[(3)H]Adenosine uptake in brainstem membranes of CD-1 mice lacking the adenosine A(2a) receptor.

Life sciences 20040528

The role of intraspinal adenosine A1 receptors in sympathetic regulation.

European journal of pharmacology 20040510

Novel amino acid derived natural products from the ascidian Atriolum robustum: identification and pharmacological characterization of a unique adenosine derivative.

Journal of medicinal chemistry 20040422

Regional and endothelial differences in cyclosporine attenuation of adenosine receptor-mediated vasorelaxations.

Journal of cardiovascular pharmacology 20040401

NECA and bradykinin at reperfusion reduce infarction in rabbit hearts by signaling through PI3K, ERK, and NO.

Journal of molecular and cellular cardiology 20040301

Pulmonary surfactant secretion in briefly cultured mouse type II cells.

American journal of physiology. Lung cellular and molecular physiology 20040201

A1 and A2A adenosine receptor modulation of alpha 1-adrenoceptor-mediated contractility in human cultured prostatic stromal cells.

British journal of pharmacology 20040101

A2B adenosine receptor agonists: synthesis and biological evaluation of 2-phenylhydroxypropynyl adenosine and NECA derivatives.

Nucleosides, nucleotides & nucleic acids 20040101

Effects of stable adenosine receptor agonists on bone marrow hematopoietic cells as inferred from the cytotoxic action of 5-fluorouracil.

Physiological research 20040101

The role of the basolateral outwardly rectifying chloride channel in human airway epithelial anion secretion.

American journal of respiratory cell and molecular biology 20031201

Structure of the N-terminal domain of GRP94. Basis for ligand specificity and regulation.

The Journal of biological chemistry 20031128

A(2A) adenosine receptor ligands and proinflammatory cytokines induce PC 12 cell death through apoptosis.

Biochemical pharmacology 20031115

Modeling the adenosine receptors: comparison of the binding domains of A2A agonists and antagonists.

Journal of medicinal chemistry 20031106

Oligodendrocytes express functional A1 adenosine receptors that stimulate cellular migration.

Glia 20031101

Comparative pharmacological studies on the A2 adenosine receptor agonist 5'-n-ethyl-carboxamidoadenosine and its F19 isotope labelled derivative.

Journal of pharmacological sciences 20031101

Adenosine receptor agonists: from basic medicinal chemistry to clinical development.

Expert opinion on emerging drugs 20031101

Effect of taurine deficiency on adenosine receptor-mediated relaxation of the rat aorta.

Vascular pharmacology 20031101

The G(s)-coupled adenosine A(2B) receptor recruits divergent pathways to regulate ERK1/2 and p38.

Experimental cell research 20031015

Adenosine-induced IL-6 expression in pituitary folliculostellate cells is mediated via A2b adenosine receptors coupled to PKC and p38 MAPK.

British journal of pharmacology 20031001

Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidine derivatives as adenosine receptor antagonists. Influence of the N5 substituent on the affinity at the human A 3 and A 2B adenosine receptor subtypes: a molecular modeling investigation.

Journal of medicinal chemistry 20030925

Antagonist pharmacology of adenosine A2B receptors from rat, guinea pig and dog.

European journal of pharmacology 20030815

Blockade of A2A adenosine receptors prevents basic fibroblast growth factor-induced reactive astrogliosis in rat striatal primary astrocytes.

Glia 20030801

An angiogenic switch in macrophages involving synergy between Toll-like receptors 2, 4, 7, and 9 and adenosine A(2A) receptors.

The American journal of pathology 20030801

Adenosine slows migration of dendritic cells but does not affect other aspects of dendritic cell maturation.

The Journal of investigative dermatology 20030801

Activation of mast cells by immunoglobulin E-receptor cross-linkage, but not through adenosine receptors, induces A1 expression and promotes survival.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20030801

Adenosine A 2B receptors modulate cAMP levels and induce CREB but not ERK1/2 and p38 phosphorylation in rat skeletal muscle cells.

Biochemical and biophysical research communications 20030718

Characterization of adenosine receptor(s) involved in adenosine-induced bronchoconstriction in an allergic mouse model.

American journal of physiology. Lung cellular and molecular physiology 20030601

Purinergic receptors on microglial cells: functional expression in acute brain slices and modulation of microglial activation in vitro.

The European journal of neuroscience 20030601

Adenosine affects the calcium dynamics of rat portal vein.

Autonomic & autacoid pharmacology 20030601

Binding of HTLV-1 virions to T cells occurs by a temperature and calcium-dependent process and is blocked by certain type 2 adenosine receptor antagonists.

Virus research 20030501

N6-cyclopentyl-2-(3-phenylaminocarbonyltriazene-1-yl)adenosine (TCPA), a very selective agonist with high affinity for the human adenosine A1 receptor.

Journal of medicinal chemistry 20030410

Adenosine stimulates anion secretion across cultured and native adult human vas deferens epithelia.

Biology of reproduction 20030301

Central nervous system effects of caffeine and adenosine on fatigue.

American journal of physiology. Regulatory, integrative and comparative physiology 20030201

Regional differences in the adenosine A(2) receptor-mediated modulation of contractions in rat vas deferens.

European journal of pharmacology 20030124

Adenosine receptor subtypes mediating coronary vasodilation in rat hearts.

Journal of cardiovascular pharmacology 20030101

Synthesis of carbocyclic analogues of MECA and NECA 1,2-disubstituted as potential adenosine receptor agonists.

Nucleosides, nucleotides & nucleic acids 20030101

Effects of doxazosin and propranolol on A2A adenosine receptors in essential hypertension.

Hypertension (Dallas, Tex. : 1979) 20021201

Possible role of mast cells in cineole-induced scratching behavior in mice.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20021001

Structural determinants of A(3) adenosine receptor activation: nucleoside ligands at the agonist/antagonist boundary.

Journal of medicinal chemistry 20020926

The effects of adenosine receptor agonists and antagonists on morphine state-dependent memory of passive avoidance.

Neurobiology of learning and memory 20020901

Involvement of mitogen protein kinase cascade in agonist-mediated human A(3) adenosine receptor regulation.

Biochimica et biophysica acta 20020819

Relaxation of the mouse isolated aorta and carotid artery in response to adenosine analogues in genetically-modified mice lacking the adenosine A(2A) receptor.

Naunyn-Schmiedeberg's archives of pharmacology 20020801

Induction of interleukin 8 release from the HMC-1 mast cell line: synergy between stem cell factor and activators of the adenosine A(2b) receptor.

Biochemical pharmacology 20020715

Synergistic up-regulation of vascular endothelial growth factor expression in murine macrophages by adenosine A(2A) receptor agonists and endotoxin.

The American journal of pathology 20020601

[The [18F]-FNECA serves as a suitable radioligand for PET investigation of purinergic receptor expression].

Orvosi hetilap 20020526

Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

The Journal of biological chemistry 20020419

Adenosine receptor-mediated control of in vitro release of pain-related neuropeptides from the rat spinal cord.

European journal of pharmacology 20020419

Role of vasodilator-stimulated phosphoprotein in PKA-induced changes in endothelial junctional permeability.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020401

Dopaminergic mechanism for caffeine-produced cocaine seeking in rats.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20020401

Rhythmic gene expression in pituitary depends on heterologous sensitization by the neurohormone melatonin.

Nature neuroscience 20020301

Basolateral potassium channels of rabbit colon epithelium: role in sodium absorption and chloride secretion.

Biochimica et biophysica acta 20020218

Cardiac effects of adenosine in A(2A) receptor knockout hearts: uncovering A(2B) receptors.

American journal of physiology. Heart and circulatory physiology 20020201

Evidence for an atypical receptor mediating the augmented bronchoconstrictor response to adenosine induced by allergen challenge in actively sensitized Brown Norway rats.

British journal of pharmacology 20020201

Effects of adenosine on bacterial lipopolysaccharide- and interleukin 1-induced nitric oxide release from equine articular chondrocytes.

American journal of veterinary research 20020201

Effects of adenosine agonists on consumptive behaviour and body temperature.

The Journal of pharmacy and pharmacology 20020201

2,5'-Disubstituted adenosine derivatives: evaluation of selectivity and efficacy for the adenosine A(1), A(2A), and A(3) receptor.

Journal of medicinal chemistry 20020117

Comparison of the vascular effects of adenosine in isolated mouse heart and aorta.

American journal of physiology. Heart and circulatory physiology 20020101

Cocaine-induced hyperactivity is more influenced by adenosine receptor agonists than amphetamine-induced hyperactivity.

Polish journal of pharmacology 20020101

7-Nitrobenzofurazan (NBD) derivatives of 5'-N-ethylcarboxamidoadenosine (NECA) as new fluorescent probes for human A(3) adenosine receptors.

Bioorganic & medicinal chemistry letters 20011203

Regulation of SP-B and SP-C secretion in rat type II cells in primary culture.

American journal of physiology. Lung cellular and molecular physiology 20011201

Neoceptor concept based on molecular complementarity in GPCRs: a mutant adenosine A(3) receptor with selectively enhanced affinity for amine-modified nucleosides.

Journal of medicinal chemistry 20011122

Effects of adenosine receptor agonists and antagonists on pentylenetetrazole-induced amnesia.

European journal of pharmacology 20011102

Inhibition of human mast cell activation with the novel selective adenosine A(2B) receptor antagonist 3-isobutyl-8-pyrrolidinoxanthine (IPDX)(2).

Biochemical pharmacology 20011101

Adenosine-mediated hypotension in in vivo guinea-pig: receptors involved and role of NO.

British journal of pharmacology 20011001

The plasma protein extravasation induced by adenosine and its analogues in the rat dorsal skin: evidence for the involvement of capsaicin sensitive primary afferent neurones and mast cells.

British journal of pharmacology 20010901

Pharmacological characterization of adenosine receptors in PGT-beta mouse pineal gland tumour cells.

British journal of pharmacology 20010901

Arrestin specificity for G protein-coupled receptors in human airway smooth muscle.

The Journal of biological chemistry 20010831

P2Y(11) receptor expression by human lymphocytes: evidence for two cAMP-linked purinoceptors.

European journal of pharmacology 20010831

5'-O-alkyl ethers of N,2-substituted adenosine derivatives: partial agonists for the adenosine A1 and A3 receptors.

Journal of medicinal chemistry 20010830

Why do asthmatic subjects respond so strongly to inhaled adenosine?

Life sciences 20010803

Proliferation, migration, and ERK activation in human retinal endothelial cells through A(2B) adenosine receptor stimulation.

Investigative ophthalmology & visual science 20010801

Functional characterization of coronary vascular adenosine receptors in the mouse.

British journal of pharmacology 20010801

Introduction of alkynyl chains on C-8 of adenosine led to very selective antagonists of the A(3) adenosine receptor.

Bioorganic & medicinal chemistry letters 20010723

Withdrawal and bidirectional cross-withdrawal responses in rats treated with adenosine agonists and morphine.

Life sciences 20010706

Role of cyclic nucleotides in vasodilations of the rat thoracic aorta induced by adenosine analogues.

British journal of pharmacology 20010701

Modulation of ethanol-induced motor incoordination by mouse striatal A(1) adenosinergic receptor.

Brain research bulletin 20010701

Protective effect of adenosine receptor agonists in a new model of epilepsy--seizures evoked by mitochondrial toxin, 3-nitropropionic acid, in mice.

Neuroscience letters 20010608

Differential effects of UTP, ATP, and adenosine on ciliary activity of human nasal epithelial cells.

American journal of physiology. Cell physiology 20010601

Ring-Constrained (N)-methanocarba nucleosides as adenosine receptor agonists: independent 5'-uronamide and 2'-deoxy modifications.

Bioorganic & medicinal chemistry letters 20010521

Age-related changes in adenosine-mediated relaxation of coronary and aortic smooth muscle.

American journal of physiology. Heart and circulatory physiology 20010501

Aberrant amplification of A(2A) receptor signaling in striatal cells expressing mutant huntingtin.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010501

Glucocorticoid enhances the response of type II cells from newborn rats to surfactant secretagogues.

Biochimica et biophysica acta 20010430

Pharmacology of a unique adenosine binding site in rat brain using a selective ligand.

Clinical and experimental pharmacology & physiology 20010401

Effect of 9-(6,7-dideoxy-beta-D-allo-hept-5-ynofuranosyl)adenine on noradrenaline release from vascular sympathetic nerves.

Clinical and experimental pharmacology & physiology 20010401

Adenosine inhibits neutrophil vascular endothelial growth factor release and transendothelial migration via A2B receptor activation.

Shock (Augusta, Ga.) 20010401

Adenosine agonists CGS 21680 and NECA inhibit the initiation of cocaine self-administration.

Pharmacology, biochemistry, and behavior 20010401

[3H]MRS 1754, a selective antagonist radioligand for A(2B) adenosine receptors.

Biochemical pharmacology 20010315

Adenosine enhances neuroexcitability by inhibiting a slow postspike afterhyperpolarization in rabbit vagal afferent neurons.

Circulation 20010306

Design, synthesis, and evaluation of novel A2A adenosine receptor agonists.

Journal of medicinal chemistry 20010215

Extracellular adenosine-induced apoptosis in mouse neuroblastoma cells: studies on involvement of adenosine receptors and adenosine uptake.

Biochemical pharmacology 20010215

Regulation of G protein-coupled receptor-adenylyl cyclase responsiveness in human airway smooth muscle by exogenous and autocrine adenosine.

American journal of respiratory cell and molecular biology 20010201

3-Aryl[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-ones: a new class of selective A1 adenosine receptor antagonists.

Journal of medicinal chemistry 20010201

Nucleosides and nucleotides. 200. Reinvestigation of 5'-N-ethylcarboxamidoadenosine derivatives: structure-activity relationships for P(3) purinoceptor-like proteins.

Journal of medicinal chemistry 20010118

Adenosine A2B receptors behave as an alternative anchoring protein for cell surface adenosine deaminase in lymphocytes and cultured cells.

Molecular pharmacology 20010101

Cloning of a chick A3 adenosine receptor: characterization of ligand binding and receptor-effector coupling of chick A1 and A3 adenosine receptors.

Naunyn-Schmiedeberg's archives of pharmacology 20010101

Characterization of prejunctional purinoceptors inhibiting noradrenaline release in rat mesenteric arteries.

Japanese journal of pharmacology 20010101

Synthesis and adenosine receptor affinity and potency of 8-alkynyl derivatives of adenosine.

Nucleosides, nucleotides & nucleic acids 20010101

Role of endothelium in ischaemia-induced myocardial dysfunction of isolated working hearts: cardioprotection by activation of adenosine A(2A) receptors.

Journal of autonomic pharmacology 20010101

Why are A(2B) receptors low-affinity adenosine receptors? Mutation of Asn273 to Tyr increases affinity of human A(2B) receptor for 2-(1-Hexynyl)adenosine.

Molecular pharmacology 20001201

[(3)H]MRE 3008F20: a novel antagonist radioligand for the pharmacological and biochemical characterization of human A(3) adenosine receptors.

Molecular pharmacology 20000501

Activation of the A3 adenosine receptor affects cell cycle progression and cell growth.

Naunyn-Schmiedeberg's archives of pharmacology 20000301

Characterization of human A(2B) adenosine receptors: radioligand binding, western blotting, and coupling to G(q) in human embryonic kidney 293 cells and HMC-1 mast cells.

Molecular pharmacology 19991001

2-Substituted N-ethylcarboxamidoadenosine derivatives as high-affinity agonists at human A3 adenosine receptors.

Naunyn-Schmiedeberg's archives of pharmacology 19990801

Identification of the adenine binding site of the human A1 adenosine receptor.

The Journal of biological chemistry 19990205

Differences in the order of potency for agonists but not antagonists at human and rat adenosine A2A receptors.

Biochemical pharmacology 19990101

2'-C-Methyl analogues of selective adenosine receptor agonists: synthesis and binding studies.

Journal of medicinal chemistry 19980507

Comparative pharmacology of human adenosine receptor subtypes - characterization of stably transfected receptors in CHO cells.

Naunyn-Schmiedeberg's archives of pharmacology 19980101

Effect of adenosine receptor agonists and antagonists on morphine-induced catalepsy in mice.

European journal of pharmacology 19971029

Mechanism and pressor relevance of the short-term cardiovascular and renin excitatory actions of the selective A2A-adenosine receptor agonists.

Journal of cardiovascular pharmacology 19970901

Pharmacological characterization of novel A3 adenosine receptor-selective antagonists.

Neuropharmacology 19970901

Adenosine A2 receptors modulate haloperidol-induced catalepsy in rats.

European journal of pharmacology 19970611

Characterization of human A2A adenosine receptors with the antagonist radioligand [3H]-SCH 58261.

British journal of pharmacology 19970501

Characterization of the human brain putative A2B adenosine receptor expressed in Chinese hamster ovary (CHO.A2B4) cells.

British journal of pharmacology 19961101

Effects of adenosine analogues on apomorphine-induced penile erection in rats.

General pharmacology 19951201

Site-directed mutagenesis identifies residues involved in ligand recognition in the human A2a adenosine receptor.

The Journal of biological chemistry 19950609

Species difference in the G protein selectivity of the human and bovine A1-adenosine receptor.

The Journal of biological chemistry 19941223

Role of the second extracellular loop of adenosine receptors in agonist and antagonist binding. Analysis of chimeric A1/A3 adenosine receptors.

The Journal of biological chemistry 19941007

Structure-activity relationships of N6-benzyladenosine-5'-uronamides as A3-selective adenosine agonists.

Journal of medicinal chemistry 19940304

Functional characterization of the A2b adenosine receptor in NIH 3T3 fibroblasts.

Biochemical pharmacology 19940302

A threonine residue in the seventh transmembrane domain of the human A1 adenosine receptor mediates specific agonist binding.

The Journal of biological chemistry 19940128

Noradrenaline but not dopamine involved in NMDA receptor-mediated hyperalgesia induced by theophylline in awake rats.

European journal of pharmacology 19940124

Molecular cloning and characterization of the human A3 adenosine receptor.

Proceedings of the National Academy of Sciences of the United States of America 19931101

N-ethyl-carboxamide adenosine inhibits perioral dyskinesias induced by sulpiride + SKF 38393 in rabbits.

European journal of pharmacology 19921113

[Effects of agonists and antagonists of benzodiazepine, GABA and NMDA receptors, on caffeine-induced seizures in mice].

Yakubutsu, seishin, kodo = Japanese journal of psychopharmacology 19920801

Enhanced fatty acid biosynthesis and normal surfactant secretion in hypertrophic rat type II cells.

The American journal of physiology 19910601

Allosteric enhancement of adenosine A1 receptor binding and function by 2-amino-3-benzoylthiophenes.

Molecular pharmacology 19901201

Binding of the adenosine A2 receptor ligand [3H]CGS 21680 to human and rat brain: evidence for multiple affinity sites.

Journal of neurochemistry 19901101

Hemodynamic effects of adenosine agonists in the conscious spontaneously hypertensive rat.

The Journal of pharmacology and experimental therapeutics 19900901

Caffeine-induced seizures: apparent proconvulsant action of N-ethyl carboxamidoadenosine (NECA).

Life sciences 19900101

[3H]CGS 21680, a selective A2 adenosine receptor agonist directly labels A2 receptors in rat brain.

The Journal of pharmacology and experimental therapeutics 19891201

Comparison of the behavioral effects of adenosine agonists and dopamine antagonists in mice.

Psychopharmacology 19890101

Potent convulsant actions of the adenosine receptor antagonist, xanthine amine congener (XAC).

Life sciences 19890101

Doxofylline, an antiasthmatic drug lacking affinity for adenosine receptors.

Archives internationales de pharmacodynamie et de therapie 19880101