Home Other Building Blocks 1H-1,2,3,4-tetrazole-5-carboxamide

1H-1,2,3,4-tetrazole-5-carboxamide

CAS No.:
32366-22-6
Catalog Number:
AG01BVJZ
Molecular Formula:
C2H3N5O
Molecular Weight:
113.0781
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Product Description
Catalog Number:
AG01BVJZ
Chemical Name:
1H-1,2,3,4-tetrazole-5-carboxamide
CAS Number:
32366-22-6
Molecular Formula:
C2H3N5O
Molecular Weight:
113.0781
MDL Number:
MFCD22194330
IUPAC Name:
2H-tetrazole-5-carboxamide
InChI:
InChI=1S/C2H3N5O/c3-1(8)2-4-6-7-5-2/h(H2,3,8)(H,4,5,6,7)
InChI Key:
FLABMTVDNODXQV-UHFFFAOYSA-N
SMILES:
NC(=O)c1nnn[nH]1
NSC Number:
282059
Properties
Complexity:
103  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
113.034g/mol
Formal Charge:
0
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
113.08g/mol
Monoisotopic Mass:
113.034g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
97.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-1.3  
Literature
Title Journal
Neuroprotection in glaucoma. Indian journal of ophthalmology 20110101
Selective inhibition of protein kinase C beta(2) attenuates inducible nitric oxide synthase-mediated cardiovascular abnormalities in streptozotocin-induced diabetic rats. Diabetes 20091001
Antinociceptive effects of tetrazole inhibitors of endocannabinoid inactivation: cannabinoid and non-cannabinoid receptor-mediated mechanisms. British journal of pharmacology 20081101
Glutamate-stimulated peroxynitrite production in a brain-derived endothelial cell line is dependent on N-methyl-D-aspartate (NMDA) receptor activation. Biochemical pharmacology 20070115
Inducible nitric oxide synthase, Nos2, does not mediate optic neuropathy and retinopathy in the DBA/2J glaucoma model. BMC neuroscience 20070101
Drug intervention can correct subnormal retinal oxygenation response in experimental diabetic retinopathy. Investigative ophthalmology & visual science 20050801
Regulation of the early subnormal retinal oxygenation response in experimental diabetes by inducible nitric oxide synthase. Diabetes 20040101
A selective inhibitor of inducible nitric oxide synthase inhibits exhaled breath nitric oxide in healthy volunteers and asthmatics. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030701
Loss of retinal ganglion cells following retinal ischemia: the role of inducible nitric oxide synthase. Experimental eye research 20021101
Role of nitric oxide in allergic inflammation and bronchial hyperresponsiveness. European journal of pharmacology 20020927
A prodrug of a selective inhibitor of inducible nitric oxide synthase is neuroprotective in the rat model of glaucoma. Journal of glaucoma 20020601
Synthesis and biological characterization of L-N(6)-(1-iminoethyl)lysine 5-tetrazole-amide, a prodrug of a selective iNOS inhibitor. Journal of medicinal chemistry 20020411
Properties