Home Other Building Blocks 3,4-dihydropyridin-2(1H)-one

3,4-dihydropyridin-2(1H)-one

CAS No.:
57147-25-8
Catalog Number:
AG01BJ2R
Molecular Formula:
C5H7NO
Molecular Weight:
97.1152
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Product Description
Catalog Number:
AG01BJ2R
Chemical Name:
3,4-dihydropyridin-2(1H)-one
CAS Number:
57147-25-8
Molecular Formula:
C5H7NO
Molecular Weight:
97.1152
IUPAC Name:
3,4-dihydro-1H-pyridin-2-one
InChI:
InChI=1S/C5H7NO/c7-5-3-1-2-4-6-5/h2,4H,1,3H2,(H,6,7)
InChI Key:
ZPOODPZCZLCUAN-UHFFFAOYSA-N
SMILES:
O=C1CCC=CN1
UNII:
T0LO6RP873
Properties
Complexity:
107  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
97.053g/mol
Formal Charge:
0
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
97.117g/mol
Monoisotopic Mass:
97.053g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
29.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.1  
Literature
Title Journal
2,3-Dihydro-1,2-Diphenyl-substituted 4H-Pyridinone derivatives as new anti Flaviviridae inhibitors. Chemical biology & drug design 20110601
Dehydrogenative [4 + 2] cycloaddition of formamides with alkynes through double C-H activation. Journal of the American Chemical Society 20110316
Asymmetric synthesis of all the known phlegmarine alkaloids. The Journal of organic chemistry 20101217
Synthesis and in vitro toxicity of 4-MTA, its characteristic clandestine synthesis byproducts and related sulfur substituted alpha-alkylthioamphetamines. Bioorganic & medicinal chemistry 20100601
Regioselective nucleophilic addition to pyridinium salts: a new route to substituted dihydropyridones. Organic letters 20091203
Discovery of tricyclic 5,6-dihydro-1H-pyridin-2-ones as novel, potent, and orally bioavailable inhibitors of HCV NS5B polymerase. Bioorganic & medicinal chemistry letters 20091115
Gold(I)-catalyzed coupling reactions for the synthesis of diverse small molecules using the build/couple/pair strategy. Journal of the American Chemical Society 20090422
Synthesis of conformationally constrained peptidomimetics using multicomponent reactions. The Journal of organic chemistry 20090116
Novel hypoglycemic dihydropyridones serendipitously discovered from O- versus C-alkylation in the synthesis of VMAT2 antagonists. Bioorganic & medicinal chemistry letters 20080915
Reversal of nucleophilicity of enamides in water: control of cyclization pathways by reaction media for the orthogonal synthesis of dihydropyridinone and pyrrolidinone Clausena alkaloids. Organic letters 20080619
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A flexible six-component reaction to access constrained depsipeptides based on a dihydropyridinone core. The Journal of organic chemistry 20071221
Domino electrocyclization/azide-capture/schmidt rearrangement of dienones: one-step synthesis of dihydropyridones from simple building blocks. Journal of the American Chemical Society 20071003
Synthesis of (R)-dihydropyridones as key intermediates for an efficient access to piperidine alkaloids. Molecules (Basel, Switzerland) 20070410
Synthesis of the benzo-fused indolizidine alkaloid mimics. Beilstein journal of organic chemistry 20070101
Application of the aza-Achmatowicz oxidative rearrangement for the stereoselective synthesis of the Cassia and Prosopis alkaloid family. The Journal of organic chemistry 20061027
The ammonia-free partial reduction of substituted pyridinium salts. Organic & biomolecular chemistry 20060321
Tandem directed lithiations of N-Boc-1,2-dihydropyridines toward highly functionalized 2,3-dihydro-4-pyridones. Organic letters 20051208
Heterocyclic derivative syntheses by palladium-catalyzed oxidative cyclization-alkoxycarbonylation of substituted gamma-oxoalkynes. The Journal of organic chemistry 20050624
Partial reduction of pyridinium salts as a versatile route to dihydropyridones. Organic letters 20050203
Synthesis of beta-amino acids based on oxidative cleavage of dihydropyridone derivatives. Organic letters 20040930
Asymmetric total synthesis of (+)-cannabisativine. The Journal of organic chemistry 20040806
Weakly oriented liquid-crystal NMR solvents as a general tool to determine relative configurations. Chemistry (Weinheim an der Bergstrasse, Germany) 20030922
Antifungal amides from Piper arboreum and Piper tuberculatum. Phytochemistry 20020301
The [2+2]-photocycloaddition of aromatic aldehydes and ketones to 3,4-dihydro-2-pyridones: regioselectivity, diastereoselectivity, and reductive ring opening of the product oxetanes. Chemistry (Weinheim an der Bergstrasse, Germany) 20011015
Properties