Home Other Building Blocks N'-hydroxybenzenecarboximidamide hydrochloride

N'-hydroxybenzenecarboximidamide hydrochloride

CAS No.:
99277-23-3
Catalog Number:
AG01B9MG
Molecular Formula:
C7H9ClN2O
Molecular Weight:
172.6122
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Product Description
Catalog Number:
AG01B9MG
Chemical Name:
N'-hydroxybenzenecarboximidamide hydrochloride
CAS Number:
99277-23-3
Molecular Formula:
C7H9ClN2O
Molecular Weight:
172.6122
MDL Number:
MFCD06656049
IUPAC Name:
N'-hydroxybenzenecarboximidamide;hydrochloride
InChI:
InChI=1S/C7H8N2O.ClH/c8-7(9-10)6-4-2-1-3-5-6;/h1-5,10H,(H2,8,9);1H
InChI Key:
CVOJDESLSXPMSK-UHFFFAOYSA-N
SMILES:
ON=C(c1ccccc1)N.Cl
Properties
Complexity:
128  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
1  
Exact Mass:
172.04g/mol
Formal Charge:
0
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
172.612g/mol
Monoisotopic Mass:
172.04g/mol
Rotatable Bond Count:
1  
Topological Polar Surface Area:
58.6A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Insight into technetium amidoxime complex: oxo technetium(V) complex of N-substituted benzamidoxime as new basic structure for molecular imaging. Inorganic chemistry 20110207
Reduction of N(ω)-hydroxy-L-arginine by the mitochondrial amidoxime reducing component (mARC). The Biochemical journal 20110115
A novel and specific fluorescence reaction for uracil. Analytica chimica acta 20100803
The fourth molybdenum containing enzyme mARC: cloning and involvement in the activation of N-hydroxylated prodrugs. Journal of medicinal chemistry 20081225
Involvement of stearoyl-CoA desaturase in the reduction of amidoxime prodrugs. Xenobiotica; the fate of foreign compounds in biological systems 20080901
Identification of the missing component in the mitochondrial benzamidoxime prodrug-converting system as a novel molybdenum enzyme. The Journal of biological chemistry 20061117
Hepatic, extrahepatic, microsomal, and mitochondrial activation of the N-hydroxylated prodrugs benzamidoxime, guanoxabenz, and Ro 48-3656 ([[1-[(2s)-2-[[4-[(hydroxyamino)iminomethyl]benzoyl]amino]-1-oxopropyl]-4-piperidinyl]oxy]-acetic acid). Drug metabolism and disposition: the biological fate of chemicals 20051101
Characterization and partial purification of the rat and human enzyme systems active in the reduction of N-hydroxymelagatran and benzamidoxime. Drug metabolism and disposition: the biological fate of chemicals 20050401
Metabolism of benzamidoxime (N-hydroxyamidine) in human hepatocytes and role of UDP-glucuronosyltransferases. Xenobiotica; the fate of foreign compounds in biological systems 20050101
Phase 2 metabolites of N-hydroxylated amidines (amidoximes): synthesis, in vitro formation by pig hepatocytes, and mutagenicity testing. Chemical research in toxicology 20010301
Properties