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Ampiroxicam

CAS No.:
99464-64-9
Catalog Number:
AG019FUX
Molecular Formula:
C20H21N3O7S
Molecular Weight:
447.4616
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
500mg
98%
In Stock USA
United States
$68
- +
1g
98%
In Stock USA
United States
$112
- +
5g
98%
In Stock USA
United States
$239
- +
10g
98%
In Stock USA
United States
$408
- +
Product Description
Catalog Number:
AG019FUX
Chemical Name:
Ampiroxicam
CAS Number:
99464-64-9
Molecular Formula:
C20H21N3O7S
Molecular Weight:
447.4616
MDL Number:
MFCD00866079
IUPAC Name:
ethyl 1-[[2-methyl-1,1-dioxo-3-(pyridin-2-ylcarbamoyl)-1λ6,2-benzothiazin-4-yl]oxy]ethyl carbonate
InChI:
InChI=1S/C20H21N3O7S/c1-4-28-20(25)30-13(2)29-18-14-9-5-6-10-15(14)31(26,27)23(3)17(18)19(24)22-16-11-7-8-12-21-16/h5-13H,4H2,1-3H3,(H,21,22,24)
InChI Key:
LSNWBKACGXCGAJ-UHFFFAOYSA-N
SMILES:
CCOC(=O)OC(OC1=C(C(=O)Nc2ccccn2)N(C)S(=O)(=O)c2c1cccc2)C
NSC Number:
759807
Properties
Complexity:
808  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
447.11g/mol
Formal Charge:
0
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
447.462g/mol
Monoisotopic Mass:
447.11g/mol
Rotatable Bond Count:
8  
Topological Polar Surface Area:
133A^2
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0
XLogP3:
4  
Literature
Title Journal
Oxicam structure in non-steroidal anti-inflammatory drugs is essential to exhibit Akt-mediated neuroprotection against 1-methyl-4-phenyl pyridinium-induced cytotoxicity. European journal of pharmacology 20120215
Inhibition of myeloid cell leukemia-1 by tolfenamic acid induces apoptosis in mucoepidermoid carcinoma. Oral diseases 20110701
Chemopreventive effect of tolfenamic acid on KB human cervical cancer cells and tumor xenograft by downregulating specificity protein 1. European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20110301
3-Benzoyl-4-hydr-oxy-2-methyl-2H-1,2-benzothia-zine 1,1-dioxide. Acta crystallographica. Section E, Structure reports online 20100401
Premedication with cyclooxygenase-2 inhibitor meloxicam reduced postoperative pain in patients after oral surgery. International journal of oral and maxillofacial surgery 20060701
Evaluation of gastric acid secretion in two patients (each aged over 90 years) with Helicobacter pylori-negative nonsteroidal anti-inflammatory drug-caused duodenal ulcers. Journal of gastroenterology 20030101
[Preemptive analgesia for postoperative pain after frontotemporal craniotomy]. No shinkei geka. Neurological surgery 20020201
Preoperative ampiroxicam reduces postoperative pain after hand surgery. Journal of hand surgery (Edinburgh, Scotland) 20010801
Randomized clinical trial of primary treatment for temporomandibular joint disk displacement without reduction and without osseous changes: a combination of NSAIDs and mouth-opening exercise versus no treatment. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20010601
Properties