Name: Name:Ibuprofen Lysine
Brand: Angene
SKU: AG019FUN
Rating: 90 (10 reviews)

Catalog Number:

AG019FUN

Chemical Name:

Ibuprofen Lysine

CAS Number:

57469-77-9

Molecular Formula:

C19H32N2O4

Molecular Weight:

352.4684

MDL Number:

MFCD01716155

IUPAC Name:

(2S)-2,6-diaminohexanoic acid;2-[4-(2-methylpropyl)phenyl]propanoic acid

InChI:

InChI=1S/C13H18O2.C6H14N2O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15;7-4-2-1-3-5(8)6(9)10/h4-7,9-10H,8H2,1-3H3,(H,14,15);5H,1-4,7-8H2,(H,9,10)/t;5-/m.0/s1

InChI Key:

IHHXIUAEPKVVII-ZSCHJXSPSA-N

SMILES:

CC(Cc1ccc(cc1)C(C(=O)O)C)C.NCCCC[C@@H](C(=O)O)N

Complexity:

309

Compound Is Canonicalized:

Yes

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Defined Bond Stereocenter Count:

Exact Mass:

352.236g/mol

Formal Charge:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Isotope Atom Count:

Molecular Weight:

352.475g/mol

Monoisotopic Mass:

352.236g/mol

Rotatable Bond Count:

Topological Polar Surface Area:

127A^2

Undefined Atom Stereocenter Count:

Undefined Bond Stereocenter Count:

Title	Journal
Severe pulmonary hypertension with therapeutic L-lysine ibuprofen in 2 preterm neonates.	Pediatrics 20120501
Ibuprofen lysinate and sodium ibuprofen for prophylaxis of patent ductus arteriosus in preterm neonates.	Indian pediatrics 20120101
Effect of ibuprofen on bilirubin-albumin binding affinity in premature infants.	Journal of perinatal medicine 20110101
A randomized, double-blind, placebo-controlled trial on intravenous ibuprofen L-lysine for the early closure of nonsymptomatic patent ductus arteriosus within 72 hours of birth in extremely low-birth-weight infants.	American journal of perinatology 20090301
An optimized ibuprofen dosing scheme for preterm neonates with patent ductus arteriosus, based on a population pharmacokinetic and pharmacodynamic study.	British journal of clinical pharmacology 20080501
Treatment of patent ductus arteriosus: indomethacin or ibuprofen?	Journal of perinatology : official journal of the California Perinatal Association 20080501
Effect of ibuprofen L-lysinate on bilirubin binding to albumin as measured by saturation index and horseradish peroxidase assays.	Journal of perinatology : official journal of the California Perinatal Association 20080401
Nonselective cyclo-oxygenase inhibitors and glomerular filtration rate in preterm neonates.	Pediatric nephrology (Berlin, Germany) 20051101
Ibuprofen extrudate, a novel, rapidly dissolving ibuprofen formulation: relative bioavailability compared to ibuprofen lysinate and regular ibuprofen, and food effect on all formulations.	Journal of clinical pharmacology 20050901
Effect of lactic acid and iontophoresis on drug permeation across rabbit ear skin.	International journal of pharmaceutics 20050323
Stability of ibuprofen in injection solutions.	American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050315
Prophylactic ibuprofen in premature infants: a multicentre, randomised, double-blind, placebo-controlled trial.	Lancet (London, England) 20041101
Comparison of different ibuprofen-amino acid compounds with respect to emulsifying and cytotoxic properties.	International journal of pharmaceutics 20040415
Post-iontophoresis transport of ibuprofen lysine across rabbit ear skin.	International journal of pharmaceutics 20031106
Effect of a single dose of ibuprofen lysinate before embryo transfer on pregnancy rates in cows.	Reproduction (Cambridge, England) 20010101