Home Other Building Blocks Salinomycin

Salinomycin

CAS No.:
53003-10-4
Catalog Number:
AG019FSN
Molecular Formula:
C42H70O11
Molecular Weight:
750.9986
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
98+%
1 week
United States
$96
- +
10mg
98+%
1 week
United States
$163
- +
25mg
98+%
1 week
United States
$280
- +
Product Description
Catalog Number:
AG019FSN
Chemical Name:
Salinomycin
CAS Number:
53003-10-4
Molecular Formula:
C42H70O11
Molecular Weight:
750.9986
MDL Number:
MFCD25541652
IUPAC Name:
(2R)-2-[(2R,5S,6R)-6-[(2S,3S,4S,6R)-6-[(3S,5S,7R,9S,10S,12R,15R)-3-[(2R,5R,6S)-5-ethyl-5-hydroxy-6-methyloxan-2-yl]-15-hydroxy-3,10,12-trimethyl-4,6,8-trioxadispiro[4.1.57.35]pentadec-13-en-9-yl]-3-hydroxy-4-methyl-5-oxooctan-2-yl]-5-methyloxan-2-yl]butanoic acid
InChI:
InChI=1S/C42H70O11/c1-11-29(38(46)47)31-15-14-23(4)36(50-31)27(8)34(44)26(7)35(45)30(12-2)37-24(5)22-25(6)41(51-37)19-16-32(43)42(53-41)21-20-39(10,52-42)33-17-18-40(48,13-3)28(9)49-33/h16,19,23-34,36-37,43-44,48H,11-15,17-18,20-22H2,1-10H3,(H,46,47)/t23-,24-,25+,26-,27-,28-,29+,30-,31+,32+,33+,34+,36+,37-,39-,40+,41-,42-/m0/s1
InChI Key:
KQXDHUJYNAXLNZ-XQSDOZFQSA-N
SMILES:
CC[C@H]([C@H]1O[C@]2(C=C[C@H]([C@@]3(O2)CC[C@@](O3)(C)[C@H]2CC[C@]([C@@H](O2)C)(O)CC)O)[C@@H](C[C@@H]1C)C)C(=O)[C@H]([C@H]([C@@H]([C@@H]1O[C@H](CC[C@@H]1C)[C@H](C(=O)O)CC)C)O)C
EC Number:
258-290-1
UNII:
62UXS86T64
Properties
Complexity:
1320  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
18  
Defined Bond Stereocenter Count:
0
Exact Mass:
750.492g/mol
Formal Charge:
0
Heavy Atom Count:
53  
Hydrogen Bond Acceptor Count:
11  
Hydrogen Bond Donor Count:
4  
Isotope Atom Count:
0
Molecular Weight:
751.011g/mol
Monoisotopic Mass:
750.492g/mol
Rotatable Bond Count:
12  
Topological Polar Surface Area:
161A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
5.7  
Literature
Title Journal
Salinomycin induces primary chicken cardiomyocytes death via mitochondria mediated apoptosis. Chemico-biological interactions 20180225
Salinomycin attenuates liver cancer stem cell motility by enhancing cell stiffness and increasing F-actin formation via the FAK-ERK1/2 signalling pathway. Toxicology 20170601
Salinomycin suppresses TGF-β1-induced epithelial-to-mesenchymal transition in MCF-7 human breast cancer cells. Chemico-biological interactions 20160325
Preclinical drug metabolism and pharmacokinetics of salinomycin, a potential candidate for targeting human cancer stem cells. Chemico-biological interactions 20151005
Salinomycin exerts anticancer effects on human breast carcinoma MCF-7 cancer stem cells via modulation of Hedgehog signaling. Chemico-biological interactions 20150225
Synthesis, anticancer and antibacterial activity of salinomycin N-benzyl amides. Molecules (Basel, Switzerland) 20141125
Salinomycin induces apoptosis in cisplatin-resistant colorectal cancer cells by accumulation of reactive oxygen species. Toxicology letters 20131024
Combinatorial treatment of mammospheres with trastuzumab and salinomycin efficiently targets HER2-positive cancer cells and cancer stem cells. International journal of cancer 20121215
Antiproliferative activity of salinomycin and its derivatives. Bioorganic & medicinal chemistry letters 20121201
Exploration of natural compounds as sources of new bifunctional scaffolds targeting cholinesterases and beta amyloid aggregation: the case of chelerythrine. Bioorganic & medicinal chemistry 20121115
Effects of the veterinary pharmaceutical salinomycin and its formulation on the plant Brassica rapa. Archives of environmental contamination and toxicology 20121101
Effects of anticoccidial and antibiotic growth promoter programs on broiler performance and immune status. Research in veterinary science 20121001
Sorption and desorption of salinomycin sodium in clay, loamy sand, and sandy soils. Environmental monitoring and assessment 20120901
Detection and quantitative analysis of 21 veterinary drugs in river water using high-pressure liquid chromatography coupled to tandem mass spectrometry. Environmental science and pollution research international 20120901
Effects of nicarbazin on the blood glucose and liver glycogen statuses of male broilers. Poultry science 20120901
Salinomycin, a p-glycoprotein inhibitor, sensitizes radiation-treated cancer cells by increasing DNA damage and inducing G2 arrest. Investigational new drugs 20120801
Synthesis and antimicrobial activity of amide derivatives of polyether antibiotic-salinomycin. Bioorganic & medicinal chemistry letters 20120715
Simultaneous determination of human and veterinary antibiotics in various environmental matrices by rapid resolution liquid chromatography-electrospray ionization tandem mass spectrometry. Journal of chromatography. A 20120629
Identification of drugs including a dopamine receptor antagonist that selectively target cancer stem cells. Cell 20120608
Cancer stem cells and metastasis. Seminars in cancer biology 20120601
Effects of sodium butyrate and salinomycin upon intestinal microbiota, mucosal morphology and performance of broiler chickens. Archives of animal nutrition 20120401
Salinomycin: a new cancer drug candidate. Chemical biology & drug design 20120301
Salinomycin toxicity causes deaths of calves on two Scottish dairy farms. The Veterinary record 20120204
Salinomycin sensitizes antimitotic drugs-treated cancer cells by increasing apoptosis via the prevention of G2 arrest. Biochemical and biophysical research communications 20120203
Comparison of the oral bioavailability and tissue disposition of monensin and salinomycin in chickens and turkeys. Journal of veterinary pharmacology and therapeutics 20120201
Salinomycin inhibits prostate cancer growth and migration via induction of oxidative stress. British journal of cancer 20120103
A late-stage intermediate in salinomycin biosynthesis is revealed by specific mutation in the biosynthetic gene cluster. Chembiochem : a European journal of chemical biology 20120102
The Wnt/β-catenin signaling pathway: a potential therapeutic target in the treatment of triple negative breast cancer. Journal of cellular biochemistry 20120101
The eradication of breast cancer and cancer stem cells using octreotide modified paclitaxel active targeting micelles and salinomycin passive targeting micelles. Biomaterials 20120101
Biotic transformation of anticoccidials in soil using a lab-scale bio-reactor as a precursor-tool. Chemosphere 20120101
Simultaneous determination of five polyether ionophores using liquid chromatography with one-step fluorescent derivatization. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20120101
Report on the 3'rd scientific meeting of the 'Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie' (NEUROWIND e.V.) held in Motzen, Germany, Nov. 4'th - Nov. 6'th, 2011. Experimental & translational stroke medicine 20120101
Cancer stem cells and novel targets for antitumor strategies. Current pharmaceutical design 20120101
Correlation coefficients between different methods of expressing bacterial quantification using real time PCR. International journal of molecular sciences 20120101
Enhancing effects on vacuole-targeting fungicidal activity of amphotericin B. Frontiers in microbiology 20120101
Curcumin: updated molecular mechanisms and intervention targets in human lung cancer. International journal of molecular sciences 20120101
Anticoccidial effect of supplemental dietary Galla Rhois against infection with Eimeria tenella in chickens. Avian pathology : journal of the W.V.P.A 20120101
Quantification of ionophores in aged poultry litter using liquid chromatography tandem mass spectrometry. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20120101
Determination of narasin and monensin in bovine, swine, and chicken tissues by liquid chromatography with tandem mass spectrometry: first action 2011.24. Journal of AOAC International 20120101
Rapid method for the simultaneous determination of six ionophores in feed by liquid chromatography/mass spectrometry. Journal of AOAC International 20120101
Salinomycin induces autophagy in colon and breast cancer cells with concomitant generation of reactive oxygen species. PloS one 20120101
Impact of Salinomycin on human cholangiocarcinoma: induction of apoptosis and impairment of tumor cell proliferation in vitro. BMC cancer 20120101
Combination of salinomycin and gemcitabine eliminates pancreatic cancer cells. Cancer letters 20111227
In vitro destruction of Eimeria oocysts by essential oils. Veterinary parasitology 20111215
Salinomycin inhibits osteosarcoma by targeting its tumor stem cells. Cancer letters 20111201
Antimicrobial susceptibilities of Listeria monocytogenes isolated in Japan. The Journal of veterinary medical science 20111201
Development and validation of an UPLC-MS/MS method for the determination of ionophoric and synthetic coccidiostats in vegetables. Analytical and bioanalytical chemistry 20111201
Salinomycin toxicity in dairy calves. The Veterinary record 20111119
Lower prevalence of antibiotic-resistant Enterococci on U.S. conventional poultry farms that transitioned to organic practices. Environmental health perspectives 20111101
Species characterization and minimum inhibitory concentration patterns of Brachyspira species isolates from swine with clinical disease. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 20111101
Salinomycin can effectively kill ALDH(high) stem-like cells on gastric cancer. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20111001
Multiple-antibiotic resistance of Enterococcus faecalis and Enterococcus faecium from cecal contents in broiler chicken and turkey flocks slaughtered in Canada and plasmid colocalization of tetO and ermB genes. Journal of food protection 20111001
Salinomycin-induced apoptosis of human prostate cancer cells due to accumulated reactive oxygen species and mitochondrial membrane depolarization. Biochemical and biophysical research communications 20110916
Rapid quantification of ionophores in feeds by liquid chromatography-tandem mass spectrometry. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 20110901
Determination of eleven coccidiostats in animal feed by liquid chromatography-tandem mass spectrometry at cross contamination levels. Analytica chimica acta 20110826
Development and validation of a multi-residue liquid chromatography-tandem mass spectrometry confirmatory method for eleven coccidiostats in eggs. Analytica chimica acta 20110826
Inhibition of Wnt signaling and cancer stem cells. Oncotarget 20110801
Unraveling the complexity of basal-like breast cancer. Oncotarget 20110801
Detecting and targeting mesenchymal-like subpopulations within squamous cell carcinomas. Cell cycle (Georgetown, Tex.) 20110615
Salinomycin selectively targets 'CD133+' cell subpopulations and decreases malignant traits in colorectal cancer lines. Annals of surgical oncology 20110601
Microbial community and metabolomic comparison of irritable bowel syndrome faeces. Journal of medical microbiology 20110601
Salinomycin induces calpain and cytochrome c-mediated neuronal cell death. Cell death & disease 20110601
Anticoccidial effects of coumestans from Eclipta alba for sustainable control of Eimeria tenella parasitosis in poultry production. Veterinary parasitology 20110419
Susceptibility of Clostridium difficile toward antimicrobial agents used as feed additives for food animals. Microbial drug resistance (Larchmont, N.Y.) 20110301
Effects of salinomycin on cancer stem cell in human lung adenocarcinoma A549 cells. Medicinal chemistry (Shariqah (United Arab Emirates)) 20110301
Rapid and reliable identification of ionophore antibiotics in feeds by liquid chromatography-tandem mass spectrometry. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc 20110301
The efficacy of anticoccidial products against Eimeria spp. in northern bobwhites. Avian diseases 20110301
Salinomycin sensitizes cancer cells to the effects of doxorubicin and etoposide treatment by increasing DNA damage and reducing p21 protein. British journal of pharmacology 20110201
Eradicating cancer cells: struggle with a chameleon. Oncotarget 20110201
Megacities as sources for pathogenic bacteria in rivers and their fate downstream. International journal of microbiology 20110101
Novel Perspectives on p53 Function in Neural Stem Cells and Brain Tumors. Journal of oncology 20110101
Cooperation of cancer stem cell properties and epithelial-mesenchymal transition in the establishment of breast cancer metastasis. Journal of oncology 20110101
Activation of β-catenin and Akt pathways by Twist are critical for the maintenance of EMT associated cancer stem cell-like characters. BMC cancer 20110101
Rac1 targeting suppresses human non-small cell lung adenocarcinoma cancer stem cell activity. PloS one 20110101
Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression. Breast cancer research : BCR 20110101
Evaluation of Iron-induced Oxidative Stress and its Amelioration by Certain Herbs in Broilers. Toxicology international 20110101
Biology of the Mi-2/NuRD Complex in SLAC (Stemness, Longevity/Ageing, and Cancer). Gene regulation and systems biology 20110101
A new approach to the analysis of nicarbazin and ionophores in eggs by HPLC/MS/MS. Journal of AOAC International 20110101
Effect of Antibiotic Growth Promoters on Intestinal Microbiota in Food Animals: A Novel Model for Studying the Relationship between Gut Microbiota and Human Obesity? Frontiers in microbiology 20110101
Cd(II) and Pb(II) complexes of the polyether ionophorous antibiotic salinomycin. Chemistry Central journal 20110101
Drug-tolerant cancer cells show reduced tumor-initiating capacity: depletion of CD44 cells and evidence for epigenetic mechanisms. PloS one 20110101
Impacts of poultry house environment on poultry litter bacterial community composition. PloS one 20110101
Breast cancer epithelial-to-mesenchymal transition: examining the functional consequences of plasticity. Breast cancer research : BCR 20110101
Niclosamide suppresses cancer cell growth by inducing Wnt co-receptor LRP6 degradation and inhibiting the Wnt/β-catenin pathway. PloS one 20110101
Simultaneous determination of polyether ionophores, macrolides and lincosamides in hen eggs by liquid chromatography-electrospray ionization tandem mass spectrometry using a simple solvent extraction. Analytica chimica acta 20101203
Biodegradation of polyether algal toxins--isolation of potential marine bacteria. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20101201
Effects of ionophores on liver CYP1A and 3A in male broilers. Journal of veterinary pharmacology and therapeutics 20101201
Accidental salinomycin intoxication in calves. The Canadian veterinary journal = La revue veterinaire canadienne 20101001
Kitlow stem cells cause resistance to Kit/platelet-derived growth factor alpha inhibitors in murine gastrointestinal stromal tumors. Gastroenterology 20100901
Identification and quantification of salinomycin in intoxicated human plasma by liquid chromatography-electrospray tandem mass spectrometry. Analytical and bioanalytical chemistry 20100901
Comparison of Eimeria species distribution and salinomycin resistance in commercial broiler operations utilizing different coccidiosis control strategies. Avian diseases 20100901
Selection of single chain variable fragment (scFv) antibodies from a hyperimmunized phage display library for the detection of the antibiotic monensin. Journal of immunological methods 20100831
Anticoccidial activity of maslinic acid against infection with Eimeria tenella in chickens. Parasitology research 20100801
The cancer stem cell selective inhibitor salinomycin is a p-glycoprotein inhibitor. Blood cells, molecules & diseases 20100615
Interference free detection for small molecules: probing the Mn2+-doped effect and cysteine capped effect on the ZnS nanoparticles for coccidiostats and peptide analysis in SALDI-TOF MS. The Analyst 20100501
Salinomycin overcomes ABC transporter-mediated multidrug and apoptosis resistance in human leukemia stem cell-like KG-1a cells. Biochemical and biophysical research communications 20100416
The effect of composting on the degradation of a veterinary pharmaceutical. Bioresource technology 20100401
The effect of commonly used anticoccidials and antibiotics in a subclinical necrotic enteritis model. Avian pathology : journal of the W.V.P.A 20100201
Synthesis of natural products containing spiroketals via intramolecular hydrogen abstraction. Organic & biomolecular chemistry 20100107
Veterinary pharmaceuticals and antibiotic resistance of Escherichia coli isolates in poultry litter from commercial farms and controlled feeding trials. Poultry science 20100101
Retrospective study of salinomycin toxicosis in 66 cats. Veterinary medicine international 20100101
Comparative efficacy of an organic Acid blend and bacitracin methylene disalicylate as growth promoters in broiler chickens: effects on performance, gut histology, and small intestinal milieu. Veterinary medicine international 20100101
Biosynthesis and molecular genetics of polyketides in marine dinoflagellates. Marine drugs 20100101
Pathway signature and cellular differentiation in clear cell renal cell carcinoma. PloS one 20100101
Isolation of deoxynivalenol-transforming bacteria from the chicken intestines using the approach of PCR-DGGE guided microbial selection. BMC microbiology 20100101
Cancerous stem cells: deviant stem cells with cancer-causing misbehavior. Stem cell research & therapy 20100101
Targeting breast cancer stem cells: fishing season open! Breast cancer research : BCR 20100101
Increasing CD44+/CD24(-) tumor stem cells, and upregulation of COX-2 and HDAC6, as major functions of HER2 in breast tumorigenesis. Molecular cancer 20100101
The regulation of miRNA-211 expression and its role in melanoma cell invasiveness. PloS one 20100101
Modeling the clonal heterogeneity of stem cells. Theoretical biology & medical modelling 20100101
Oxidative stress induced by lead and antioxidant potential of certain adaptogens in poultry. Toxicology international 20100101
Markers of tumor-initiating cells predict chemoresistance in breast cancer. PloS one 20100101
Salinomycin in cancer: A new mission for an old agent. Molecular medicine reports 20100101
Salinomycin induces apoptosis and overcomes apoptosis resistance in human cancer cells. Biochemical and biophysical research communications 20091218
Effects and mechanisms of action of ionophorous antibiotics valinomycin and salinomycin-Na on Babesia gibsoni in vitro. The Journal of parasitology 20091201
Validation of a multi-residue liquid chromatography-tandem mass spectrometry confirmatory method for 10 anticoccidials in eggs according to Commission Decision 2002/657/EC. Journal of chromatography. A 20091113
Multi-residue confirmatory method for the determination of twelve coccidiostats in chicken liver using liquid chromatography tandem mass spectrometry. Journal of chromatography. A 20091113
High-throughput screening finds potential killer of cancer stem cells. Journal of the National Cancer Institute 20091104
The activity and compatibility of the antibiotic tiamulin with other drugs in poultry medicine--A review. Poultry science 20091101
New drug against cancer stem cells may prevent disease recurrence and spread. ONS connect 20091101
[Determination of 5 polyether antibiotics in chicken tissues by liquid chromatography-electrospray ionization tandem mass spectrometry]. Se pu = Chinese journal of chromatography 20091101
Evaluation of PCR and DNA sequencing for direct detection of Clostridium perfringens in the intestinal tract of broilers. Avian diseases 20090901
Determination of veterinary pharmaceuticals in poultry litter and soil by methanol extraction and liquid chromatography-tandem mass spectrometry. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20090901
Identification of selective inhibitors of cancer stem cells by high-throughput screening. Cell 20090821
Taking aim at aggressive cancer cells. Cancer biology & therapy 20090801
The role of probiotics in the poultry industry. International journal of molecular sciences 20090801
Genotype comparison of sorbitol-negative Escherichia coli isolates from healthy broiler chickens from different commercial farms. Poultry science 20090701
Incidence of animal poisoning cases in the Czech Republic: current situation. Interdisciplinary toxicology 20090601
Fast liquid chromatography/multiple-stage mass spectrometry of coccidiostats. Rapid communications in mass spectrometry : RCM 20090501
Disruption of a mitochondrial MutS DNA repair enzyme homologue confers drug resistance in the parasite Toxoplasma gondii. Molecular microbiology 20090401
Diversity and susceptibility of Enterococcus isolated from cattle before and after harvest. Journal of food protection 20090401
Monoclonal antibody production and immunochemical detection of polyether antibiotics. Archives of pharmacal research 20090301
Fate and antibacterial potency of anticoccidial drugs and their main abiotic degradation products. Environmental pollution (Barking, Essex : 1987) 20090201
Synergistic fungicidal activities of polymyxin B and ionophores, and their dependence on direct disruptive action of polymyxin B on fungal vacuole. The Journal of antibiotics 20090201
Effects of salinomycin on cell-mediated immunity of broiler chickens against hydropericardium syndrome and Newcastle disease viruses. Poultry science 20090101
Role of sgcR3 in positive regulation of enediyne antibiotic C-1027 production of Streptomyces globisporus C-1027. BMC microbiology 20090101
Occurrence and elimination of antibiotics at four sewage treatment plants in Japan and their effects on bacterial ammonia oxidation. Water science and technology : a journal of the International Association on Water Pollution Research 20090101
Dietary supplementation of mannan-oligosaccharide enhances neonatal immune responses in chickens during natural exposure to Eimeria spp. Acta veterinaria Scandinavica 20090101
Responses of plasma acetate metabolism to hop (Humulus lupulus L.) in sheep. International journal of biological sciences 20090101
Synthetic lethality: a framework for the development of wiser cancer therapeutics. Genome medicine 20090101
Epithelial to mesenchymal transition and breast cancer. Breast cancer research : BCR 20090101
[Salinomycin and semduramicin in different concentrations on the broilers eimeriosis control]. Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria 20090101
Compatibility of a combination of tiamulin and chlortetracycline with salinomycin in feed during a pulsed medication program coadministration in broilers. Poultry science 20081201
Characterization of Streptomyces spp. isolated from the sea surface microlayer in the Trondheim Fjord, Norway. Marine drugs 20081201
Investigation of chicken intestinal bacterial communities by 16S rRNA targeted fluorescence in situ hybridization. Antonie van Leeuwenhoek 20081001
Determination of ionophore coccidiostats in feedingstuffs by liquid chromatography-tandem mass spectrometry Part I. Application to targeted feed. Journal of pharmaceutical and biomedical analysis 20080805
Compatibility of a combination of tiamulin plus chlortetracycline with salinomycin in feed during a long-term co-administration in broilers. Poultry science 20080801
Pharmacological evaluation of contractile activity of the dog heartworm Dirofilaria immitis. Veterinary research communications 20080301
Natural Products and Medicinal Chemistry--the 22nd Mona Symposium. IDrugs : the investigational drugs journal 20080301
Conformation and location of membrane-bound salinomycin-sodium complex deduced from NMR in isotropic bicelles. Journal of the American Chemical Society 20071205
Effects of polyether ionophores on the protective immune responses of broiler chickens against Angara disease and Newcastle disease viruses. Veterinary research communications 20071001
Liquid chromatography-tandem mass spectrometric assays for salinomycin in mouse plasma, liver, brain and small intestinal contents and in OptiMEM cell culture medium. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070815
Salinomycin toxicosis in horses. Journal of the American Veterinary Medical Association 20070615
Direct-fed microbial PrimaLac and salinomycin modulate whole-body and intestinal oxygen consumption and intestinal mucosal cytokine production in the broiler chick. Poultry science 20070601
Microarchitecture and spatial relationship between bacteria and ileal, cecal, and colonic epithelium in chicks fed a direct-fed microbial, PrimaLac, and salinomycin. Poultry science 20070601
An integrated sample preparation to determine coccidiostats and emerging Fusarium-mycotoxins in various poultry tissues with LC-MS/MS. Molecular nutrition & food research 20070501
Efficacy of some anticoccidial drugs for treating coccidial enteritis of the common carp caused by Goussia carpelli (Apicomplexa: Eimeriidae). Acta veterinaria Hungarica 20070301
Evaluation of the efficacy of a probiotic containing Lactobacillus, Bifidobacterium, Enterococcus, and Pediococcus strains in promoting broiler performance and modulating cecal microflora composition and metabolic activities. Poultry science 20070201
Impact of salinomycin on the intestinal microflora of broiler chickens. Acta veterinaria Scandinavica 20070101
Multiple regulatory genes in the salinomycin biosynthetic gene cluster of Streptomyces albus CCM 4719. Folia microbiologica 20070101
Prevalence and antimicrobial resistance of enterococci isolated from retail fruits, vegetables, and meats. Journal of food protection 20061201
Persistence of antibiotics such as macrolides, tiamulin and salinomycin in soil. Environmental pollution (Barking, Essex : 1987) 20061001
Increased level of Eimeria sensitivity to diclazuril after using a live coccidial vaccine. Avian diseases 20060901
Elimination of macrolides, tiamulin, and salinomycin during manure storage. Archives of environmental contamination and toxicology 20060701
Occurrence of ionophore antibiotics in water and sediments of a mixed-landscape watershed. Water research 20060701
Microbial community composition of the ileum and cecum of broiler chickens as revealed by molecular and culture-based techniques. Poultry science 20060701
Evaluation of a Bacillus stearothermophilus tube test as a screening tool for anticoccidial residues in poultry. Journal of veterinary science 20060601
Effect of dietary zinc level on serum carotenoid levels, body and shank pigmentation of chickens after experimental infection with coccidia. Archives of animal nutrition 20060601
Simultaneous determination of four coccidiostats in eggs and broiler meat: validation of an LC-MS/MS method. Food additives and contaminants 20060501
A case of salinomycin intoxication in turkeys. The Canadian veterinary journal = La revue veterinaire canadienne 20060301
Stereoselective synthesis of the western hemisphere of salinomycin. Organic letters 20060202
Tiamulin resistance in porcine Brachyspira pilosicoli isolates. Research in veterinary science 20060201
Determination of monensin, narasin, and salinomycin in mineral premixes, supplements, and animal feeds by liquid chromatography and post-column derivatization: collaborative study. Journal of AOAC International 20060101
Combined effect of salinomycin and feeding on whole body glucose kinetics in sheep fed a high-concentrate diet. Reproduction, nutrition, development 20060101
[The effect of betain on biology and morphology of developmental stages of Eimeria acervulina in broiler chicks experimentally infected]. Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria 20060101
Antiparasitic and immunomodulatory effect of innovative treatments against Myxobolus sp. infection in Diplodus puntazzo. Veterinary parasitology 20051210
Incidence of residues of nine anticoccidials in eggs. Food additives and contaminants 20051101
HPLC determination of salinomycin and related compounds in fermentation media of Streptomyces albus and premixes. Journal of pharmaceutical and biomedical analysis 20050915
Synthesis and SAR of 2,3-diarylpyrrole inhibitors of parasite cGMP-dependent protein kinase as novel anticoccidial agents. Bioorganic & medicinal chemistry letters 20050701
Effects of Natustat supplementation on performance, feed efficiency and intestinal lesion scores in broiler chickens challenged with Eimeria acervulina, Eimeria maxima and Eimeria tenella. Veterinary parasitology 20050630
Rapid analysis of trace levels of antibiotic polyether ionophores in surface water by solid-phase extraction and liquid chromatography with ion trap tandem mass spectrometric detection. Journal of chromatography. A 20050218
Performance and nutrient retention responses of broilers to dietary oxyhalogenic and ionic salts. Poultry science 20050201
Determination of the ionophoric coccidiostats narasin, monensin, lasalocid and salinomycin in eggs by liquid chromatography/tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20050101
The impact of a successful anti-myxosporean treatment on the phagocyte functions of juvenile and adult Sparus aurata L. International journal of immunopathology and pharmacology 20050101
Efficient and sensitive detection of residues of nine coccidiostats in egg and muscle by liquid chromatography-electrospray tandem mass spectrometry. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041225
Efficacy and toxicity of orally administrated anti-coccidial drugs for innovative treatments of Myxobolus sp. infection in Puntazzo puntazzo. Diseases of aquatic organisms 20041213
Development of multiclass methods for drug residues in eggs: silica SPE cleanup and LC-MS/MS analysis of ionophore and macrolide residues. Journal of agricultural and food chemistry 20041117
An unaddressed issue of agricultural terrorism: a case study on feed security. Journal of animal science 20041101
Radical oxidative cyclization of spiroacetals to bis-spiroacetals: an overview. Molecules (Basel, Switzerland) 20040531
Coccidiosis control by administering toltrazuril in the drinking water for a 2-day period. Veterinary parasitology 20040507
The effects of salinomycin and roxarsone on the performance of broilers when included in the feed for four, five, or six weeks and infected with Eimeria species during the starter or grower phase of production. Poultry science 20040501
Rapid time-resolved fluoroimmunoassay for the screening of narasin and salinomycin residues in poultry and eggs. Journal of agricultural and food chemistry 20040407
Further characterization of porcine Brachyspira hyodysenteriae isolates with decreased susceptibility to tiamulin. Journal of medical microbiology 20040401
[Inhibitory effect of zinc on beta-hexosaminidase release from RBL-2H3 cells by synthetic chemicals]. Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20040401
A case of human poisoning by salinomycin, an agricultural antibiotic. The New Zealand medical journal 20040312
Isolation and selection of ionophore-tolerant Eimeria precocious lines: E. tenella, E. maxima and E. acervulina. Veterinary parasitology 20040206
A field study on the effect of the dietary use of a clinoptilolite-rich tuff, alone or in combination with certain antimicrobials, on the health status and performance of weaned, growing and finishing pigs. Research in veterinary science 20040201
Susceptibility of Clostridium perfringens strains from broiler chickens to antibiotics and anticoccidials. Avian pathology : journal of the W.V.P.A 20040201
Evaluation of zinc against salinomycin toxicity in broilers. Indian journal of physiology and pharmacology 20040101
Inhibition of resistance plasmid transfer in Escherichia coli by ionophores, chlortetracycline, bacitracin, and ionophore/antimicrobial combinations. Avian diseases 20040101
Comparison of microwave assisted extraction with conventional (homogenization, vortexing) for the determination of incurred salinomycin in chicken eggs and tissues. Journal of environmental science and health. Part. B, Pesticides, food contaminants, and agricultural wastes 20040101
Growth enhancement in broiler chickens receiving CHEMEQRTM polymeric antimicrobial. Avian pathology : journal of the W.V.P.A 20031201
Identification of new leishmanicidal peptide lead structures by automated real-time monitoring of changes in intracellular ATP. The Biochemical journal 20031001
Ionophores: their use as ruminant growth promotants and impact on food safety. Current issues in intestinal microbiology 20030901
Cloning of modular type I polyketide synthase genes from salinomycin producing strain of Streptomyces albus. Bioorganic & medicinal chemistry 20030805
Resistance to anticoccidial drugs of Dutch avian Eimeria spp. field isolates originating from 1996, 1999 and 2001. Avian pathology : journal of the W.V.P.A 20030801
Determination of antibiotics from soil by pressurized liquid extraction and liquid chromatography-tandem mass spectrometry. Journal of chromatography. A 20030627
Efficacy of selected oral chemotherapeutants against Ichthyophthirius multifiliis (Ciliophora: Ophyroglenidae) infecting rainbow trout Oncorhynchus mykiss. Diseases of aquatic organisms 20030620
Pancreatic lipase activity as influenced by unconjugated bile acids and pH, measured in vitro and in vivo. The Journal of nutritional biochemistry 20030501
Antimicrobial growth promoters and Salmonella spp., Campylobacter spp. in poultry and swine, Denmark. Emerging infectious diseases 20030401
Determination of antibiotics such as macrolides, ionophores and tiamulin in liquid manure by HPLC-MS/MS. Analytical and bioanalytical chemistry 20030401
LC determination of salinomycin in fermentation broths and premixes. Journal of pharmaceutical and biomedical analysis 20030226
Fragmentation study of salinomycin and monensin A antibiotics using electrospray quadrupole time-of-flight mass spectrometry. Rapid communications in mass spectrometry : RCM 20030101
Degradation of tryptophan and related indolic compounds by ruminal bacteria, protozoa and their mixture in vitro. Amino acids 20030101
Antimicrobial susceptibilities of Staphylococcus aureus isolated from commercial broilers in northeastern Georgia. Avian diseases 20030101
Coccidiosis control with toltrazuril in conjunction with anticoccidial medicated or nonmedicated feed. Avian diseases 20030101
Beneficial effect of beta-mannanase feed enzyme on performance of chicks challenged with Eimerla sp. and Clostridium perfringens. Avian diseases 20030101
A new method for in vitro detection of microbially produced mitochondrial toxins. Toxicology in vitro : an international journal published in association with BIBRA 20030101
[Effects of veterinary drugs on beta-hexosaminidase release from rat basophilic leukemia cells (RBL-2H3)]. Shokuhin eiseigaku zasshi. Journal of the Food Hygienic Society of Japan 20021001
Effects of orally administered chemotherapeutics (quinine, salinomycin) against Henneguya sp. Thelohán, 1892 (Myxozoa: Myxobolidae), a gill parasite in the tapir fish Gnathonemus petersii Günther, 1862 (Teleostei). Parasitology research 20020901
Potentiometric determination of polyether ionophores growth promotors in animal feed preparations. Journal of pharmaceutical and biomedical analysis 20020720
The determination of 5 anticoccidial drugs (nicarbazin, lasalocid, monensin, salinomycin and narasin) in animal livers and eggs by liquid chromatography linked with tandem mass spectrometry (LC-MS-MS). The Analyst 20020601
The use of diclazuril in extended withdrawal anticoccidial programs: 1. Efficacy against Eimeria spp. in broiler chickens in floor pens. Poultry science 20020301
Effect of antibiotics on in vitro and in vivo avian cartilage degradation. Avian diseases 20020101
Recovery of injured adrenal medulla by differentiation of pre-existing undifferentiated chromaffin cells. Toxicologic pathology 20020101
Study of resistance against some ionophores in Eimeria tenella field isolates. Veterinary parasitology 20011203
Efficient and sensitive screening and confirmation of residues of selected polyether ionophore antibiotics in liver and eggs by liquid chromatography-electrospray tandem mass spectrometry. The Analyst 20011101
Salinomycin poisoning in veal calves. The Veterinary record 20010811
The effect of salinomycin on certain blood parameters and milk quality of lactating sows. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20010801
The effect of salinomycin on health status and performance of sows and their litters: a dose titration study. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20010601
Use of anticoccidial drugs in broiler chickens in the USA: analysis for the years 1995 to 1999. Poultry science 20010501
Efficacy of diclazuril in comparison with chemical and ionophorous anticoccidials against Eimeria spp. in broiler chickens in floor pens. Poultry science 20010401
Polyether antibiotic CP44,161. Acta crystallographica. Section C, Crystal structure communications 20010101
[Oxadin effect on actinomycetes strains]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20010101
LC/MS confirmation of ionophores in animal feeds. Journal of AOAC International 20010101
Comparative investigation of salinomycin and flavophospholipol in sheep fed different composed diets. Archiv fur Tierernahrung 20010101
Anticryptosporidial activity of lasalocid and other ionophorous antibiotics in immunosuppressed rats. The Journal of infectious diseases 19931201
Properties