Orphenadrine citrate
Title | Journal |
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Liver tumor promoting effect of orphenadrine in rats and its possible mechanism of action including CAR activation and oxidative stress. | The Journal of toxicological sciences 20130101 |
Enhanced liver tumor promotion activity in rats subjected to combined administration of phenobarbital and orphenadrine. | The Journal of toxicological sciences 20130101 |
Cu(II)-catalyzed asymmetric hydrosilylation of diaryl- and aryl heteroaryl ketones: application in the enantioselective synthesis of orphenadrine and neobenodine. | Chemistry (Weinheim an der Bergstrasse, Germany) 20120611 |
[Interaction of drugs with the primary disease - when medicines exacerbate illnesses]. | Praxis 20120314 |
Reduction of tinnitus severity by the centrally acting muscle relaxant cyclobenzaprine: an open-label pilot study. | Audiology & neuro-otology 20120101 |
Validated stability-indicating reversed-phase-HPLC method for simultaneous determination of orphenadrine citrate, caffeine and aspirin. | Chemical & pharmaceutical bulletin 20120101 |
Orphenadrine induces secondarily generalized convulsive status epilepticus in rats. | Brain research bulletin 20110405 |
A predictive ligand-based Bayesian model for human drug-induced liver injury. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
Full recovery from a potentially lethal dose of orphenadrine ingestion using conservative treatment: a case report. | Human & experimental toxicology 20101101 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
Opiate sparing effect of fixed combination of diclophenac and orphenadrine after unilateral total hip arthroplasty: A double-blind, randomized, placebo-controlled, multi-centre clinical trial. | Wiener medizinische Wochenschrift (1946) 20101101 |
Determination of orphenadrine plasma levels using HPLC with diode array detection and a novel solid-phase extraction procedure in psychiatric patients. | Journal of pharmaceutical and biomedical analysis 20091015 |
The use of antipsychotic and anticholinergic antiparkinson drugs in Norway after the withdrawal of orphenadrine. | British journal of clinical pharmacology 20090801 |
The first asymmetric halogen/metal-exchange reaction: desymmetrization of alcohols with enantiotopic bromoarene substituents. | Chemistry (Weinheim an der Bergstrasse, Germany) 20090706 |
Involvement of voltage-gated sodium channels blockade in the analgesic effects of orphenadrine. | Pain 20090401 |
The use and potential abuse of anticholinergic antiparkinson drugs in Norway: a pharmacoepidemiological study. | British journal of clinical pharmacology 20090201 |
Effects of cytochrome P450 inducers and inhibitors on the pharmacokinetics of intravenous furosemide in rats: involvement of CYP2C11, 2E1, 3A1 and 3A2 in furosemide metabolism. | The Journal of pharmacy and pharmacology 20090101 |
Influence of orphenadrine upon the protective activity of various antiepileptics in the maximal electroshock-induced convulsions in mice. | Pharmacological reports : PR 20090101 |
Pharmacokinetic, metabolism and withdrawal time of orphenadrine in camels (Camelus dromedarius) after intravenous administration. | Research in veterinary science 20081201 |
[Diclofenac/orphenadrine as a combined analgetic in post-operative relief of pain]. | Orvosi hetilap 20080928 |
Effect of warnings in a medical journal on the use of orphenadrine. | Journal of evaluation in clinical practice 20080801 |
Are there alternatives to the use of quinine to treat nocturnal leg cramps? | The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20080201 |
Effects of CYP inducers and inhibitors on the pharmacokinetics of intravenous theophylline in rats: involvement of CYP1A1/2 in the formation of 1,3-DMU. | The Journal of pharmacy and pharmacology 20080101 |
Anticholinergic antiparkinson drug orphenadrine inhibits HERG channels: block attenuation by mutations of the pore residues Y652 or F656. | Naunyn-Schmiedeberg's archives of pharmacology 20071201 |
Determination of paracetamol and orphenadrine citrate in pharmaceutical tablets by modeling of spectrophotometric data using partial least-squares and artificial neural networks. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20071001 |
Evaluation of enantioselective binding of antihistamines to human serum albumin by ACE. | Electrophoresis 20070801 |
[Enzyme kinetics of schizandrin metabolism and sex differences in rat liver microsomes]. | Yao xue xue bao = Acta pharmaceutica Sinica 20070701 |
Anticholinergic drug-induced delirium in an elderly Alzheimer's dementia patient. | Archives of gerontology and geriatrics 20070101 |
Propofol metabolism is enhanced after repetitive ketamine administration in rats: the role of cytochrome P-450 2B induction. | British journal of anaesthesia 20060901 |
Acute adverse cutaneous reaction after the concomitant use of venlafaxine and orphenadrine citrate plus paracetamol in a depressed patient. | Journal of the European Academy of Dermatology and Venereology : JEADV 20060901 |
Efficacy and safety of combined piroxicam, dexamethasone, orphenadrine, and cyanocobalamin treatment in mandibular molar surgery. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20060901 |
Pharmacokinetic study of orphenadrine using high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060724 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
Torsades de pointes in congenital long QT syndrome following low-dose orphenadrine. | International journal of clinical practice 20060501 |
Catanionic mixtures involving a drug: a rather general concept that can be utilized for prolonged drug release from gels. | Journal of pharmaceutical sciences 20060401 |
Dimemorfan N-demethylation by mouse liver microsomal cytochrome P450 enzymes. | Life sciences 20050701 |
Comparison of the analgesic effects of a fixed-dose combination of orphenadrine and diclofenac (Neodolpasse) with its single active ingredients diclofenac and orphenadrine: a placebo-controlled study using laser-induced somatosensory-evoked potentials from capsaicin-induced hyperalgesic human skin. | Drugs in R&D 20050101 |
Rhythm-specific pharmacological modulation of subthalamic activity in Parkinson's disease. | Experimental neurology 20041001 |
Objective high-frequency tinnitus of middle-ear myoclonus. | The Journal of laryngology and otology 20040301 |
[Diclofenac 75mg. and 30 mg. orfenadine (Neodolpasse) versus placebo and piroxicam in postoperative analgesia after arthroscopy]. | Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca 20040101 |
Analgesic effects of low-dose intravenous orphenadrine in the state of capsaicin hyperalgesia. A randomised, placebo-controlled, double-blind cross-over study using laser somatosensory evoked potentials obtained from capsaicin-irritated skin in healthy volunteers. | Arzneimittel-Forschung 20040101 |
Upregulation of cytochromes P450 2B in rat liver by orphenadrine. | British journal of pharmacology 20030601 |
Neuronal sensitization and its behavioral correlates in a rat model of neuropathy are prevented by a cyclic analog of orphenadrine. | Journal of neurotrauma 20030601 |
Therapeutic response of benzodiazepine, orphenadrine citrate and occlusal splint association in TMD pain. | Cranio : the journal of craniomandibular practice 20030401 |
Affinity and specificity of N-methyl- D-aspartate channel blockers affect their ability to disrupt prepulse inhibition of acoustic startle in rats. | Psychopharmacology 20030201 |
Spectrophotometric determination of phenylephrine HCl and orphenadrine citrate in pure and in dosage forms. | Journal of pharmaceutical and biomedical analysis 20021107 |
Nefopam, an analogue of orphenadrine, protects against both NMDA receptor-dependent and independent veratridine-induced neurotoxicity. | Amino acids 20020101 |
Acute intoxication with orphenadrine and clozapine. | Forensic science international 20011115 |
Non-sustained ventricular tachycardia due to low-dose orphenadrine. | The American journal of medicine 20011001 |
Cytochrome P4502B6 and 2C9 do not metabolize midazolam: kinetic analysis and inhibition study with monoclonal antibodies. | British journal of anaesthesia 20010401 |
Orphenadrine prevents 3-nitropropionic acid-induced neurotoxicity in vitro and in vivo. | British journal of pharmacology 20010201 |
[Experience gained with the drug amizon in the treatment of patients with mumps, with special reference to its effects on some biochemical markers]. | Likars'ka sprava 20010101 |
[Diagnostic image (17). Acute dystonia induced by prochlorperazine]. | Nederlands tijdschrift voor geneeskunde 20001223 |
Examination of purported probes of human CYP2B6. | Pharmacogenetics 19970601 |
Reversal of orphenadrine-induced ventricular tachycardia with physostigmine. | The Journal of emergency medicine 19910101 |
Mental impairment in Parkinson's disease. The role of anticholinergic drugs. | Acta psychiatrica Belgica 19840101 |
[Orphenadrine poisoning]. | Ugeskrift for laeger 19810316 |
An extrapyramidal syndrome after lithium therapy. | The British journal of psychiatry : the journal of mental science 19800201 |
A comparative trial of orphenadrine and tofenacin in the control of depression and extrapyramidal side-effects associated with fluphenazine decanoate therapy. | The Journal of international medical research 19760101 |
Visual hallucinations and delirium during treatment with amantadine (Symmetrel). | Journal of the American Geriatrics Society 19750501 |
[Pilot study on the effects of an antiparkinson anticholinergic agent during depressive conditions]. | L'Encephale 19750101 |
Abnormal involuntary movements induced by anticholinergic therapy. | Acta neurologica Scandinavica 19740101 |
Fluphenazine enanthate and fluphenazine decanoate: a comparison of their duration of action and motor side effects. | The American journal of psychiatry 19730701 |
Haloperidol-desipramine interaction in mice, rats and man. | Chemico-biological interactions 19700801 |
A controlled trial of anti-Parkinson drugs in drug-induced Parkinsonism. | The British journal of psychiatry : the journal of mental science 19660601 |