Home Halogens Sulfachloropyridazine

Sulfachloropyridazine

CAS No.:
80-32-0
Catalog Number:
AG00ID32
Molecular Formula:
C10H9ClN4O2S
Molecular Weight:
284.7221
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
250mg
95+%
1 week
United States
$42
- +
Product Description
Catalog Number:
AG00ID32
Chemical Name:
Sulfachloropyridazine
CAS Number:
80-32-0
Molecular Formula:
C10H9ClN4O2S
Molecular Weight:
284.7221
MDL Number:
MFCD02668080
IUPAC Name:
4-amino-N-(6-chloropyridazin-3-yl)benzenesulfonamide
InChI:
InChI=1S/C10H9ClN4O2S/c11-9-5-6-10(14-13-9)15-18(16,17)8-3-1-7(12)2-4-8/h1-6H,12H2,(H,14,15)
InChI Key:
XOXHILFPRYWFOD-UHFFFAOYSA-N
SMILES:
Nc1ccc(cc1)S(=O)(=O)Nc1ccc(nn1)Cl
EC Number:
201-269-9
UNII:
P78D9P90C0
NSC Number:
757858
Properties
Complexity:
365  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
284.013g/mol
Formal Charge:
0
Heavy Atom Count:
18  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
284.718g/mol
Monoisotopic Mass:
284.013g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
106A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1  
Literature
Title Journal
Ultrasound-assisted ionic liquid/ionic liquid-dispersive liquid-liquid microextraction for the determination of sulfonamides in infant formula milk powder using high-performance liquid chromatography. Talanta 20120915
Detection and quantitative analysis of 21 veterinary drugs in river water using high-pressure liquid chromatography coupled to tandem mass spectrometry. Environmental science and pollution research international 20120901
Development and validation of an LC-UV method for the determination of sulfonamides in animal feeds. Drug testing and analysis 20120501
Electrochemical treatment of the antibiotic sulfachloropyridazine: kinetics, reaction pathways, and toxicity evolution. Environmental science & technology 20120403
Development and validation of a multiclass method for the determination of veterinary drug residues in chicken by ultra high performance liquid chromatography-tandem mass spectrometry. Talanta 20120130
Development of an HPLC method to analyze four veterinary antibiotics in soils and aqueous media and validation through fate studies. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20120101
Sulfonamides identified as plant immune-priming compounds in high-throughput chemical screening increase disease resistance in Arabidopsis thaliana. Frontiers in plant science 20120101
Development of a high performance liquid chromatography method and a liquid chromatography-tandem mass spectrometry method with the pressurized liquid extraction for the quantification and confirmation of sulfonamides in the foods of animal origin. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110901
Studies on removing sulfachloropyridazine from groundwater with microbial bioreactors. Current microbiology 20110501
Occurrence and transport of tetracycline, sulfonamide, quinolone, and macrolide antibiotics in the Haihe River Basin, China. Environmental science & technology 20110301
Optimization and validation of the micellar electrokinetic capillary chromatographic method for simultaneous determination of sulfonamide and amphenicol-type drugs in poultry tissue. Journal of pharmaceutical and biomedical analysis 20110105
Development of a quantitative multiclass/multiresidue method for 21 veterinary drugs in shrimp. Journal of AOAC International 20110101
Lack of the delta subunit of RNA polymerase increases virulence related traits of Streptococcus mutans. PloS one 20110101
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
Multiresidue analysis of sulfonamides in meat by supramolecular solvent microextraction, liquid chromatography and fluorescence detection and method validation according to the 2002/657/EC decision. Journal of chromatography. A 20101001
Use and environmental occurrence of antibiotics in freestall dairy farms with manured forage fields. Environmental science & technology 20100901
Removal of sulfonamide antibiotics from water: Evidence of adsorption into an organophilic zeolite Y by its structural modifications. Journal of hazardous materials 20100615
Sulfonamide antibiotics embedded in high silica zeolite Y: a combined experimental and theoretical study of host-guest and guest-guest interactions. Langmuir : the ACS journal of surfaces and colloids 20100615
Development of an ultra-high-pressure liquid chromatography-tandem mass spectrometry multi-residue sulfonamide method and its application to water, manure slurry, and soils from swine rearing facilities. Journal of chromatography. A 20100219
A multivariate multianalyte screening method for sulfonamides in milk based on front-face fluorescence spectroscopy. Analytica chimica acta 20100111
Tetra-aqua-bis(pyridine-κN)cobalt(II) bis-[4-amino-N-(6-chloro-pyridazin-3-yl)benzene-sulfonamidate]. Acta crystallographica. Section E, Structure reports online 20091201
A confirmatory method for the simultaneous extraction, separation, identification and quantification of Tetracycline, Sulphonamide, Trimethoprim and Dapsone residues in muscle by ultra-high-performance liquid chromatography-tandem mass spectrometry according to Commission Decision 2002/657/EC. Journal of chromatography. A 20091113
A new and simple method to determine trace levels of sulfonamides in honey by high performance liquid chromatography with fluorescence detection. Journal of chromatography. A 20091023
Effects of oxytetracycline and sulfachloropyridazine residues on the reductive activity of Shewanella decolorationis S12. Journal of agricultural and food chemistry 20090708
Analytical method for simultaneous determination of pesticide and veterinary drug residues in milk by CE-MS. Electrophoresis 20090501
Determination of sulfonamide residues in water samples by in-line solid-phase extraction-capillary electrophoresis. Journal of chromatography. A 20090410
Determination of ten sulphonamides in egg by liquid chromatography-tandem mass spectrometry. Analytica chimica acta 20090401
Effects of agricultural conditions on the leaching behaviour of veterinary antibiotics in soils. Chemosphere 20090301
Net changes in antibiotic concentrations downstream from an effluent discharge. Journal of environmental quality 20090101
Multiresidue determination of sulfonamides in chicken meat by polymer monolith microextraction and capillary zone electrophoresis with field-amplified sample stacking. Journal of chromatography. A 20080926
Immunochemical assays for direct sulfonamide antibiotic detection in milk and hair samples using antibody derivatized magnetic nanoparticles. Journal of agricultural and food chemistry 20080213
Effects of ionic strength, temperature, and pH on degradation of selected antibiotics. Journal of environmental quality 20080101
Application of matrix solid-phase dispersion and high-performance liquid chromatography for determination of sulfonamides in honey. Journal of AOAC International 20080101
Simultaneous determination of different classes of antibiotics in fish and livestock by CE-MS. Electrophoresis 20071101
Analytical methods for multiresidue determination of sulfonamides and trimethoprim in meat and ground water samples by CE-MS and CE-MS/MS. Electrophoresis 20071101
[Simultaneous determination of nine sulfonamide residues in milk using solid phase extraction and high performance liquid chromatography]. Se pu = Chinese journal of chromatography 20070901
Monoclonal antibody-based fluorescence polarization immunoassay for sulfamethoxypyridazine and sulfachloropyridazine. Journal of agricultural and food chemistry 20070822
Pressurized liquid extraction combined with capillary electrophoresis-mass spectrometry as an improved methodology for the determination of sulfonamide residues in meat. Journal of chromatography. A 20070803
Aquatic toxicity of acetaminophen, carbamazepine, cimetidine, diltiazem and six major sulfonamides, and their potential ecological risks in Korea. Environment international 20070401
Development of an enzyme-linked immunosorbent assay for seven sulfonamide residues and investigation of matrix effects from different food samples. Journal of agricultural and food chemistry 20070321
The dissipation and transport of veterinary antibiotics in a sandy loam soil. Chemosphere 20070201
A rapid assay for dihydropteroate synthase activity suitable for identification of inhibitors. Analytical biochemistry 20070115
Simultaneous determination of 17 sulfonamides and the potentiators ormetoprim and trimethoprim in salmon muscle by liquid chromatography with tandem mass spectrometry detection. Journal of AOAC International 20070101
Determination of 10 sulfonamide residues in meat samples by liquid chromatography with ultraviolet detection. Journal of AOAC International 20070101
Application of capillary zone electrophoresis with large-volume sample stacking to the sensitive determination of sulfonamides in meat and ground water. Electrophoresis 20061001
Multiwalled carbon nanotubes as sorbent for on-line coupling of solid-phase extraction to high-performance liquid chromatography for simultaneous determination of 10 sulfonamides in eggs and pork. Journal of chromatography. A 20060915
Multiresidue determination of sulfonamides in edible catfish, shrimp and salmon tissues by high-performance liquid chromatography with postcolumn derivatization and fluorescence detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060818
Changes in antibacterial activity of triclosan and sulfa drugs due to photochemical transformations. Environmental toxicology and chemistry 20060601
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
The effect of pH and ionic strength on the sorption of sulfachloropyridazine, tylosin, and oxytetracycline to soil. Environmental toxicology and chemistry 20060401
Estimation of soil sorption coefficients of veterinary pharmaceuticals from soil properties. Environmental toxicology and chemistry 20060401
Simultaneous extraction and analysis of 11 tetracycline and sulfonamide antibiotics in influent and effluent domestic wastewater by solid-phase extraction and liquid chromatography-electrospray ionization tandem mass spectrometry. Journal of chromatography. A 20051202
In vitro toxicity of antimicrobials on RTG-2 and RTL-W1 fish cell lines. Environmental toxicology and pharmacology 20050701
Triplet-sensitized photodegradation of sulfa drugs containing six-membered heterocyclic groups: identification of an SO2 extrusion photoproduct. Environmental science & technology 20050515
Effects of sulfachlorpyridazine in MS.3-arable land: a multispecies soil system for assessing the environmental fate and effects of veterinary medicines. Environmental toxicology and chemistry 20050401
Evaluation of a lower tier exposure assessment model for veterinary medicines. Journal of agricultural and food chemistry 20050323
A lysimeter experiment to investigate the leaching of veterinary antibiotics through a clay soil and comparison with field data. Environmental pollution (Barking, Essex : 1987) 20050301
Sustained availability of trimethoprim in drinking water to achieve higher plasma sulphonamide-trimethoprim antibacterial activity in broilers. British poultry science 20050201
Analysis of Pneumocystis jirovecii DHPS alleles implicated in sulfamethoxazole resistance using an Escherichia coli model system. Microbial drug resistance (Larchmont, N.Y.) 20050101
Simultaneous determination of 16 sulfonamides in honey by liquid chromatography/tandem mass spectrometry. Journal of AOAC International 20050101
Ultrasonic extraction of veterinary antibiotics from soils and pig slurry with SPE clean-up and LC-UV and fluorescence detection. Talanta 20041115
Quantitative analysis of twelve sulfonamides in honey after acidic hydrolysis by high-performance liquid chromatography with post-column derivatization and fluorescence detection. Journal of chromatography. A 20040820
Fast and robust simultaneous determination of three veterinary antibiotics in groundwater and surface water using a tandem solid-phase extraction with high-performance liquid chromatography-UV detection. Journal of chromatography. A 20040806
Fate of veterinary antibiotics in a macroporous tile drained clay soil. Environmental toxicology and chemistry 20040501
Validation of a confirmatory method for the determination of sulphonamides in muscle according to the European Union regulation 2002/657/EC. Journal of chromatography. A 20040402
Pollution-induced community tolerance of soil microbial communities caused by the antibiotic sulfachloropyridazine. Environmental science & technology 20040215
Analysis in Escherichia coli of Plasmodium falciparum dihydropteroate synthase (DHPS) alleles implicated in resistance to sulfadoxine. International journal for parasitology 20040101
Antimicrobial use in the treatment of calf diarrhea. Journal of veterinary internal medicine 20040101
Quantitative determination of trace concentrations of tetracycline and sulfonamide antibiotics in surface water using solid-phase extraction and liquid chromatography/ion trap tandem mass spectrometry. Rapid communications in mass spectrometry : RCM 20040101
Determination of sulfonamide residues in the tissues of food animals using automated precolumn derivatization and liquid chromatography with fluorescence detection. Journal of AOAC International 20040101
Preliminary evaluation of a lateral flow immunoassay device for screening urine samples for the presence of sulphamethazine. Journal of immunological methods 20030701
Liquid chromatography-fluorescence detection for simultaneous analysis of sulfonamide residues in honey. Analytical and bioanalytical chemistry 20030601
Comparison of a liquid chromatographic method with ultraviolet and ion-trap tandem mass spectrometric detection for the simultaneous determination of sulfadiazine and trimethoprim in plasma from dogs. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030505
In vitro susceptibility of Ornithobacterium rhinotracheale to several antimicrobial drugs. Avian diseases 20030101
The sorption and transport of a sulphonamide antibiotic in soil systems. Toxicology letters 20020510
Liquid chromatographic determination of multiple sulfonamides, nitrofurans, and chloramphenicol residues in pasteurized milk. Journal of AOAC International 20020101
Stability of sulfonamides, nitrofurans, and chloramphenicol residues in preserved raw milk samples measured by liquid chromatography. Journal of AOAC International 20020101
Development of an ELISA for sulfachlorpyridazine and investigation of matrix effects from different sample extraction procedures. Food additives and contaminants 20010101
Monodrug efficacies of sulfonamides in prophylaxis for Pneumocystis carinii pneumonia. Antimicrobial agents and chemotherapy 19960401
Inhibition of recombinant Pneumocystis carinii dihydropteroate synthetase by sulfa drugs. Antimicrobial agents and chemotherapy 19950801
Drugs as allergens: detection and combining site specificities of IgE antibodies to sulfamethoxazole. Molecular immunology 19881201
Properties