Home Carboxys 3-Quinolinecarboxylic acid,1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-

3-Quinolinecarboxylic acid,1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-

CAS No.:
70458-92-3
Catalog Number:
AG00IC2E
Molecular Formula:
C17H20FN3O3
Molecular Weight:
333.3574
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
Product Description
Catalog Number:
AG00IC2E
Chemical Name:
3-Quinolinecarboxylic acid,1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-
CAS Number:
70458-92-3
Molecular Formula:
C17H20FN3O3
Molecular Weight:
333.3574
MDL Number:
MFCD00865015
IUPAC Name:
1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
InChI:
InChI=1S/C17H20FN3O3/c1-3-20-10-12(17(23)24)16(22)11-8-13(18)15(9-14(11)20)21-6-4-19(2)5-7-21/h8-10H,3-7H2,1-2H3,(H,23,24)
InChI Key:
FHFYDNQZQSQIAI-UHFFFAOYSA-N
SMILES:
CCn1cc(C(=O)O)c(=O)c2c1cc(N1CCN(CC1)C)c(c2)F
EC Number:
274-611-8
UNII:
2H52Z9F2Q5
Properties
Complexity:
545  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
333.149g/mol
Formal Charge:
0
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
333.363g/mol
Monoisotopic Mass:
333.149g/mol
Rotatable Bond Count:
3  
Topological Polar Surface Area:
64.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.3  
Literature
Title Journal
Emergence of resistance to fluoroquinolones among gram positive and gram negative clinical isolates. Pakistan journal of pharmaceutical sciences 20121001
Superparamagnetic surface molecularly imprinted nanoparticles for water-soluble pefloxacin mesylate prepared via surface initiated atom transfer radical polymerization and its application in egg sample analysis. Journal of chromatography. A 20120713
Triprotic site-specific acid-base equilibria and related properties of fluoroquinolone antibacterials. Journal of pharmaceutical and biomedical analysis 20120701
Development of a class-specific polyclonal antibody-based indirect competitive ELISA for detecting fluoroquinolone residues in milk. Journal of Zhejiang University. Science. B 20120701
Prevalence and antimicrobial resistance of Salmonella isolated from meat and meat products in Algiers (Algeria). Foodborne pathogens and disease 20120601
Triplet excimers of fluoroquinolones in aqueous media. The journal of physical chemistry. A 20120531
HD2C interacts with HDA6 and is involved in ABA and salt stress response in Arabidopsis. Journal of experimental botany 20120501
Levofloxacin-induced tendinopathy of the hip. The Annals of pharmacotherapy 20120501
Antibiotic susceptibility patterns of urinary pathogens in female outpatients. North American journal of medical sciences 20120401
Simultaneous determination of fluoroquinolones in foods of animal origin by a high performance liquid chromatography and a liquid chromatography tandem mass spectrometry with accelerated solvent extraction. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120215
Typhoid fever & vaccine development: a partially answered question. The Indian journal of medical research 20120201
Spectroscopic and photophysical properties of protonated forms of some fluoroquinolones in solutions. Journal of fluorescence 20120101
A sensitive chromatographic strip test for the rapid detection of enrofloxacin in chicken muscle. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101
Levofloxacin, tendon rupture and acute kidney injury: Thinking outside the box. Indian journal of nephrology 20120101
Selecting allosteric ribozymes. Methods in molecular biology (Clifton, N.J.) 20120101
Plasmid-Mediated Quinolone Resistance; Interactions between Human, Animal, and Environmental Ecologies. Frontiers in microbiology 20120101
Effects of systemic ornidazole, systemic and local compound ornidazole and pefloxacin mesylate on experimental periodontitis in rats. Medical science monitor : international medical journal of experimental and clinical research 20120101
Ammonia volatilization from urea-application influenced germination and early seedling growth of dry direct-seeded rice. TheScientificWorldJournal 20120101
Pantoea agglomerans in immunodeficient patients with different respiratory symptoms. TheScientificWorldJournal 20120101
Extrachromosomal DNA length and antibiograms of Staphylococcus aureus and Pseudomonas aeruginosa isolated from tears of HIV/AIDS patients after curing with sodium dodecyl sulphate. Global journal of health science 20120101
Antibiotic-resistant commensal Escherichia coli in faecal droplets from bats and poultry in Nigeria. Veterinaria italiana 20120101
Adherent umbilical hernia containing Meckel's diverticulum resected due to intraoperative injury. Przeglad lekarski 20120101
Quantitative evaluation of the impact of active efflux by p-glycoprotein and breast cancer resistance protein at the blood-brain barrier on the predictability of the unbound concentrations of drugs in the brain using cerebrospinal fluid concentration as a surrogate. The Journal of pharmacology and experimental therapeutics 20111201
Determination of quinolone residues in infant and young children powdered milk combining solid-phase extraction and ultra-performance liquid chromatography-tandem mass spectrometry. Journal of chromatography. A 20111021
Ionic liquid-based homogeneous liquid-liquid microextraction for the determination of antibiotics in milk by high-performance liquid chromatography. Journal of chromatography. A 20111014
Fluoroquinolone-associated myasthenia gravis exacerbation: evaluation of postmarketing reports from the US FDA adverse event reporting system and a literature review. Drug safety 20111001
Synergistic effects of baicalein with ciprofloxacin against NorA over-expressed methicillin-resistant Staphylococcus aureus (MRSA) and inhibition of MRSA pyruvate kinase. Journal of ethnopharmacology 20110901
Tattoo-associated Mycobacterium haemophilum skin infection in immunocompetent adult, 2009. Emerging infectious diseases 20110901
Oxidized multi-walled carbon nanotubes for the dispersive solid-phase extraction of quinolone antibiotics from water samples using capillary electrophoresis and large volume sample stacking with polarity switching. Journal of chromatography. A 20110805
Antibiotic utilization and Pseudomonas aeruginosa resistance in intensive care units. The new microbiologica 20110701
Quinolones: review of psychiatric and neurological adverse reactions. Drug safety 20110601
Oral toxicity of pefloxacin, norfloxacin, ofloxacin and ciprofloxacin: comparison of biomechanical and histopathological effects on Achilles tendon in rats. The Journal of toxicological sciences 20110601
Evidence-based guidelines for empirical therapy of neutropenic fever in Korea. The Korean journal of internal medicine 20110601
Simple, stable and sensitive electrogenerated chemiluminescence detector for high-performance liquid chromatography and its application in direct determination of multiple fluoroquinolone residues in milk. Talanta 20110515
Spectral-luminescent properties and molecular orbital treatment of some mono- and difluoroquinolones. Journal of fluorescence 20110501
Antimicrobial resistance status and prevalence rates of extended spectrum beta-lactamase (ESBL) producers isolated from a mixed human population. Bosnian journal of basic medical sciences 20110501
Clonal differences between Non-Typhoidal Salmonella (NTS) recovered from children and animals living in close contact in the Gambia. PLoS neglected tropical diseases 20110501
In vitro susceptibility of typhoidal Salmonellae against newer antimicrobial agents: a search for alternate treatment options. JPMA. The Journal of the Pakistan Medical Association 20110501
Third generation fluoroquinolones antibacterial drug based mixed-ligand Cu(II) complexes: structure, antibacterial activity, superoxide dismutase activity and DNA-interaction approach. Journal of enzyme inhibition and medicinal chemistry 20110401
Evaluation of the reproductive and developmental risks of caffeine. Birth defects research. Part B, Developmental and reproductive toxicology 20110401
Effect of different antibiotics and non-steroidal anti-inflammatory drugs on the growth of Lactobacillus casei Shirota. Current microbiology 20110301
1-Methyl-piperazine-1,4-diium dipicrate. Acta crystallographica. Section E, Structure reports online 20110201
Development of novel in silico model to predict corneal permeability for congeneric drugs: a QSPR approach. Journal of biomedicine & biotechnology 20110101
Laboratory animal models for brucellosis research. Journal of biomedicine & biotechnology 20110101
Sterilizing activity of second-line regimens containing TMC207 in a murine model of tuberculosis. PloS one 20110101
Pseudotumor cerebri and ciprofloxacin: a case report. Journal of medical case reports 20110101
Preparation and evaluation of ofloxacin-loaded palmitic acid solid lipid nanoparticles. International journal of nanomedicine 20110101
Diffusion of ofloxacin in the endocarditis vegetation assessed with synchrotron radiation UV fluorescence microspectroscopy. PloS one 20110101
A eukaryotic-type signalling system of Pseudomonas aeruginosa contributes to oxidative stress resistance, intracellular survival and virulence. BMC genomics 20110101
Detection of macrolide and disinfectant resistance genes in clinical Staphylococcus aureus and coagulase-negative staphylococci. BMC research notes 20110101
Impact of definitive therapy with beta-lactam monotherapy or combination with an aminoglycoside or a quinolone for Pseudomonas aeruginosa bacteremia. PloS one 20110101
Effect of rickettsial toxin VapC on its eukaryotic host. PloS one 20110101
Methicillin-susceptible ST398 Staphylococcus aureus responsible for bloodstream infections: an emerging human-adapted subclone? PloS one 20110101
Oxidative stress induced by fluoroquinolones on treatment for complicated urinary tract infections in Indian patients. Journal of young pharmacists : JYP 20110101
Inhibition of DNA gyrase by levofloxacin and related fluorine-containing heterocyclic compounds. Acta naturae 20110101
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. Bioorganic & medicinal chemistry letters 20101101
Preparation of high-affinity rabbit monoclonal antibodies for ciprofloxacin and development of an indirect competitive ELISA for residues in milk. Journal of Zhejiang University. Science. B 20101001
Molecular and evolutionary bases of within-patient genotypic and phenotypic diversity in Escherichia coli extraintestinal infections. PLoS pathogens 20100901
Effects of substituents on the NMR features of basic bicyclic ring systems of fluoroquinolone antibiotics and the relationships between NMR chemical shifts, molecular descriptors and drug-likeness parameters. Acta pharmaceutica (Zagreb, Croatia) 20100901
Antibiotic susceptibility pattern of urinary tract pathogens in Ibadan, Nigeria. African journal of medicine and medical sciences 20100901
Involvement of Arabidopsis histone deacetylase HDA6 in ABA and salt stress response. Journal of experimental botany 20100701
Near-infrared spectroscopy quantitative determination of pefloxacin mesylate concentration in pharmaceuticals by using partial least squares and principal component regression multivariate calibration. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100501
Selective sample pretreatment by molecularly imprinted polymer monolith for the analysis of fluoroquinolones from milk samples. Journal of chromatography. A 20100402
Effect of levofloxacin and pefloxacin on humoral immune response elicited by bovine serum albumin docked in gelatin microparticles and nanoparticles. Die Pharmazie 20100401
4-(3-Carb-oxy-1-ethyl-6-fluoro-4-oxo-1,4-dihydro-7-quinol-yl)-1-methyl-piper-azin-ium picrate. Acta crystallographica. Section E, Structure reports online 20100301
Modification of innervation pattern by fluoroquinolone treatment in the rat salivary glands. Anatomical record (Hoboken, N.J. : 2007) 20100201
An antibiotic, heavy metal resistant and halotolerant Bacillus cereus SIU1 and its thermoalkaline protease. Microbial cell factories 20100101
Biopsy proven acute interstitial nephritis after treatment with moxifloxacin. BMC nephrology 20100101
The Schnitzler syndrome. Orphanet journal of rare diseases 20100101
Susceptibility rates of pseudomonas aeruginosa strains to quinolones. Journal of laboratory physicians 20100101
Leprosy therapy, past and present: can we hope to eliminate it? Indian journal of dermatology 20100101
Mucoadhesive drug delivery system: An overview. Journal of advanced pharmaceutical technology & research 20100101
Modification of pharmacokinetics of norfloxacin following oral administration of curcumin in rabbits. Journal of veterinary science 20091201
Determination of 76 pharmaceutical drugs by liquid chromatography-tandem mass spectrometry in slaughterhouse wastewater. Journal of chromatography. A 20091120
Antimicrobial resistance and serotype distribution of Streptococcus pneumoniae strains causing childhood infection in Burkina Faso. Pakistan journal of biological sciences : PJBS 20090915
Metalloantibiotics: synthesis, characterization and antimicrobial evaluation of bismuth-fluoroquinolone complexes against Helicobacter pylori. Acta pharmaceutica (Zagreb, Croatia) 20090901
Identification of enoxacin as an inhibitor of osteoclast formation and bone resorption by structure-based virtual screening. Journal of medicinal chemistry 20090827
Pharmacokinetics of pefloxacin mesylate in human urine using capillary electrophoresis electrochemiluminescence detection. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090815
Interaction of drug based binuclear mixed-ligand complexes with DNA. Bioorganic & medicinal chemistry 20090801
Quinolones: action and resistance updated. Current topics in medicinal chemistry 20090801
Investigation on enhanced chemiluminescence reaction systems with bis(hydrogenperiodato) argentate(III) complex anion for fluoroquinolones synthetic antibiotics. Talanta 20090715
Simultaneous determination of seven fluoroquinolones in royal jelly by ultrasonic-assisted extraction and liquid chromatography with fluorescence detection. Journal of separation science 20090401
[Multi-residue determination of 11 quinolones in chicken muscle by high performance liquid chromatography with fluorescence detection]. Se pu = Chinese journal of chromatography 20090301
Rapid determination of 19 quinolone residues in spiked fish and pig muscle by high-performance liquid chromatography (HPLC) tandem mass spectrometry. Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20090301
Bis[1-ethyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxyl-ato-κO,O]-copper(II). Acta crystallographica. Section E, Structure reports online 20090301
In vitro selection of allosteric ribozymes. Methods in molecular biology (Clifton, N.J.) 20090101
[Simultaneous determination of 19 quinolone residues in honey using high performance liquid chromatography-tandem mass spectrometry]. Se pu = Chinese journal of chromatography 20090101
A comparison of fluoroquinolones versus other antibiotics for treating enteric fever: meta-analysis. BMJ (Clinical research ed.) 20090101
[Study of efficacy of modern fluoroquinolones against agent of glanders in experiments in vivo]. Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20090101
[Clinical and laboratory investigation of pefloxacin used prophylactically in operations on the liver]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20090101
A seizure attributed to ofloxacine in a woman undergoing detoxification for alcohol dependence. Case reports in medicine 20090101
Increasing resistance to quinolones: A four-year prospective study of urinary tract infection pathogens. International journal of general medicine 20090101
Trace analysis of quinolone and fluoroquinolone antibiotics from wastewaters by liquid chromatography-electrospray tandem mass spectrometry. Journal of chromatography. A 20081219
Schnitzler's syndrome: increased levels of bone formation and angiogenesis factors are reduced after successful pefloxacin treatment. Clinical lymphoma & myeloma 20081201
Imipenem-resistant Pseudomonas aeruginosa: risk factors for nosocomial infections. Journal of Korean medical science 20081201
High-level resistance to fluoroquinolones and cephalosporins in Burkholderia pseudomallei and closely related species. Transactions of the Royal Society of Tropical Medicine and Hygiene 20081201
Effects of treatment with antimicrobial agents on the human colonic microflora. Therapeutics and clinical risk management 20081201
Multicomponent kinetic spectrophotometric determination of pefloxacin and norfloxacin in pharmaceutical preparations and human plasma samples with the aid of chemometrics. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20081001
Pharmacogenomics. Indian journal of pharmacology 20081001
Anti-vRE and anti-MRSA activities of new quinolones and their synergism with commercial antibiotics. Part 2. Biocontrol science 20080901
Development of an immunochromatography strip for the rapid detection of 12 fluoroquinolones in chicken muscle and liver. Journal of agricultural and food chemistry 20080723
Studies on the crystal forms of pefloxacin: preparation, characterization, and dissolution profile. Journal of pharmaceutical sciences 20080701
Tetra-kis(dihydrogen pefloxacinium) di-μ(2)-chlorido-bis-[tetra-chloridobismuthate(III)] tetra-chloride octa-hydrate. Acta crystallographica. Section E, Structure reports online 20080701
Fluoroquinolones versus beta-lactam based regimens for the treatment of osteomyelitis: a meta-analysis of randomized controlled trials. Spine 20080501
Pharmacokinetics of pefloxacin and its metabolite norfloxacin in male and female ducks. Journal of veterinary pharmacology and therapeutics 20080401
Effect of trikatu pretreatment on the pharmacokinetics of pefloxacin administered orally in mountain Gaddi goats. Journal of veterinary science 20080301
Electroanalytical investigation and determination of pefloxacin in pharmaceuticals and serum at boron-doped diamond and glassy carbon electrodes. Talanta 20080215
Fluoroquinolone-resistant group B streptococci in acute exacerbation of chronic bronchitis. Emerging infectious diseases 20080201
Aqua-bis[1-ethyl-6-fluoro-7-(4-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxyl-ato]zinc(II) dihydrate. Acta crystallographica. Section E, Structure reports online 20080201
1-Ethyl-6-fluoro-7-(4-methyl-piperazin-4-ium-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylate hexa-hydrate. Acta crystallographica. Section E, Structure reports online 20080201
Anticoagulant-induced changes on antibiotic concentrations in the serum and bones. European journal of drug metabolism and pharmacokinetics 20080101
Concentration-time courses of pefloxacin in plasma and milk of lactating she-camels (Camelus dromedarius). Berliner und Munchener tierarztliche Wochenschrift 20080101
[Biological analysis of workers in the food sector in north Lebanon]. Eastern Mediterranean health journal = La revue de sante de la Mediterranee orientale = al-Majallah al-sihhiyah li-sharq al-mutawassit 20080101
Simultaneous determination of 13 quinolones in eggs using column high-performance liquid chromatography/electrospray ionization-tandem mass spectrometry and depletion of pefloxacin methanesulfonate in eggs. Journal of AOAC International 20080101
Antiinfective agents affecting cognition: a review. Journal of chemotherapy (Florence, Italy) 20071201
Molecularly imprinted-matrix solid-phase dispersion for selective extraction of five fluoroquinolones in eggs and tissue. Analytical chemistry 20071101
Do fluoroquinolones commonly cause arthropathy in children? CJEM 20071101
Remission of steroid- and CyA-resistant nephrotic syndrome using multiple drug immunosuppression. Pediatric nephrology (Berlin, Germany) 20071001
Chronic urticaria and monoclonal IgM gammopathy (Schnitzler syndrome): report of 11 cases treated with pefloxacin. Archives of dermatology 20070801
Ocular toxicity of fluoroquinolones. Clinical & experimental ophthalmology 20070801
[Determination of 16 quinolone residues in animal tissues using high performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry]. Se pu = Chinese journal of chromatography 20070701
Triplet excited fluoroquinolones as mediators for thymine cyclobutane dimer formation in DNA. The journal of physical chemistry. B 20070628
Effective separation and simultaneous determination of seven fluoroquinolones by capillary electrophoresis with diode-array detector. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070601
Spectrophotometric determination of pefloxacin mesylate in pharmaceuticals. Acta pharmaceutica (Zagreb, Croatia) 20070601
Update on fluoroquinolone resistance in Helicobacter pylori: new mutations leading to resistance and first description of a gyrA polymorphism associated with hypersusceptibility. International journal of antimicrobial agents 20070401
Use of 27 parenteral antimicrobial agents in north of France hospitals. Medecine et maladies infectieuses 20070201
The potential role of concentrated animal feeding operations in infectious disease epidemics and antibiotic resistance. Environmental health perspectives 20070201
Antimicrobial therapy for acute cholangitis: Tokyo Guidelines. Journal of hepato-biliary-pancreatic surgery 20070101
Antimicrobial therapy for acute cholecystitis: Tokyo Guidelines. Journal of hepato-biliary-pancreatic surgery 20070101
Meta-analysis of prophylactic parenteral antibiotic use in acute necrotizing pancreatitis. Medicina (Kaunas, Lithuania) 20070101
[Using cluster analysis for evaluation of sensitivity to antibiotics of pathogens isolated from women with genital inflammatory diseases]. Mikrobiolohichnyi zhurnal (Kiev, Ukraine : 1993) 20070101
In vitro study of staphylococci susceptibility to gatifloxacin. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20070101
[Chemotherapy activity and pharmacokinetics of the fluoroquinolones generics Ofloxacin-PhPO and Pefloxacin-genova]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20070101
[Fluoroquinolones: antimicrobial activity and chemotherapeutic efficacy with respect to various pathogens in highly dangerous diseases]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20070101
Interaction between fluoroquinolones and bovine serum albumin studied by affinity capillary electrophoresis. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20061201
Plasmid determined resistance to quinolones in clinical isolates of Gram-negative bacilli. African journal of medicine and medical sciences 20061201
Intracellular demography and the dynamics of Salmonella enterica infections. PLoS biology 20061101
Lepromatous leprosy: a review and case report. Medicina oral, patologia oral y cirugia bucal 20061101
Preparation of anti-pefloxacin antibody and development of an indirect competitive enzyme-linked immunosorbent assay for detection of pefloxacin residue in chicken liver. Journal of agricultural and food chemistry 20060920
Effects of subchronic malathion exposure on the pharmacokinetic disposition of pefloxacin. Environmental toxicology and pharmacology 20060901
Quinolones for uncomplicated acute cystitis in women. The Cochrane database of systematic reviews 20060719
Age-dependent effects on redox status, oxidative stress, mitochondrial activity and toxicity induced by fluoroquinolones on primary cultures of rabbit tendon cells. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20060601
Binding interactions of pefloxacin mesylate with bovine lactoferrin and human serum albumin. Journal of Zhejiang University. Science. B 20060601
Preparation and characterization of inclusion complexes of pefloxacin mesylate with three kinds of cyclodextrins. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20060501
Particularities of bacterial ecology of acute otitis media in an African subtropical country (Cote d'Ivoire). International journal of pediatric otorhinolaryngology 20060501
Interactive alterations of arsenic and malathion in the disposition kinetics of pefloxacin. Archives of environmental contamination and toxicology 20060501
Comparative evaluation of possible ocular photochemical toxicity of fluoroquinolones meant for ocular use in experimental models. Indian journal of experimental biology 20060501
Simultaneous determination of (fluoro)quinolone antibiotics in kidney, marine products, eggs, and muscle by enzyme-linked immunosorbent assay (ELISA). Journal of agricultural and food chemistry 20060419
Role of excited state intramolecular charge transfer in the photophysical properties of norfloxacin and its derivatives. The journal of physical chemistry. A 20060302
A clinical trial of ethionamide and prothionamide for treatment of lepromatous leprosy. The American journal of tropical medicine and hygiene 20060301
Prulifloxacin: a new antibacterial fluoroquinolone. Expert review of anti-infective therapy 20060201
JPN Guidelines for the management of acute pancreatitis: medical management of acute pancreatitis. Journal of hepato-biliary-pancreatic surgery 20060201
Residues of fluoroquinolone drugs in the cloacal gland and other tissues of Japanese quail. British poultry science 20060201
[Cholera epidemic of 2004 in Dakar, Senegal: epidemiologic, clinical and therapeutic aspects]. Medecine tropicale : revue du Corps de sante colonial 20060201
Quantitative determination of gatifloxacin, levofloxacin, lomefloxacin and pefloxacin fluoroquinolonic antibiotics in pharmaceutical preparations by high-performance liquid chromatography. Journal of pharmaceutical and biomedical analysis 20060123
Efficient approach for the reliable quantification and confirmation of antibiotics in water using on-line solid-phase extraction liquid chromatography/tandem mass spectrometry. Journal of chromatography. A 20060120
Comparative study of antibiotic-containing polymethylmetacrylate capsules and beads. Chemotherapy 20060101
Ion-activated, Gelrite-based in situ ophthalmic gels of pefloxacin mesylate: comparison with conventional eye drops. Drug delivery 20060101
Effects of pefloxacin in multi drug resistant typhoid fever. Pakistan journal of pharmaceutical sciences 20060101
Beta-lactam antibiotic-induced release of lipoteichoic acid from Staphylococcus aureus leads to activation of neutrophil granulocytes. Annals of clinical microbiology and antimicrobials 20060101
Questions about the use of antibiotics in acute pancreatitis. World journal of emergency surgery : WJES 20060101
Evaluation of carbopol-methyl cellulose based sustained-release ocular delivery system for pefloxacin mesylate using rabbit eye model. Pharmaceutical development and technology 20060101
Genital tuberculosis in a tamoxifen-treated postmenopausal woman with breast cancer and bloody vaginal discharge. Annals of clinical microbiology and antimicrobials 20060101
[Bacteriological evaluation in chronic otitis media]. Otolaryngologia polska = The Polish otolaryngology 20060101
Antimicrobial susceptibility pattern of Klebsiella species from Ebonyi State University Teaching Hospital Abakaliki, Nigeria. Nigerian journal of clinical practice 20051201
[Intracranial hypertension in an infant treated with fluoroquinolone in Madagascar]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 20051001
Musculoskeletal injury associated with fluoroquinolone antibiotics. Clinics in plastic surgery 20051001
Pharmacokinetics and tissue residues of pefloxacin and its metabolite norfloxacin in broiler chickens. British poultry science 20051001
Effects of pefloxacin in multi drug resistant typhoid Fever. Pakistan journal of pharmaceutical sciences 20051001
Ocular inserts for controlled delivery of pefloxacin mesylate: preparation and evaluation. Acta pharmaceutica (Zagreb, Croatia) 20050901
A chiral benzoquinolizine-2-carboxylic acid arginine salt active against vancomycin-resistant Staphylococcus aureus. Journal of medicinal chemistry 20050811
Synthesis and antibacterial activity of the 4-quinolone-3-carboxylic acid derivatives having a trifluoromethyl group as a novel N-1 substituent. Journal of medicinal chemistry 20050505
Clonal comparison of Staphylococcus aureus isolates from healthy pig farmers, human controls, and pigs. Emerging infectious diseases 20050501
[Drug tendon disorders]. La Tunisie medicale 20050501
[Pharmacoeconomic profile of antibiotics used in the treatment of lower respiratory tract infections in geriatric patients]. Ceska a Slovenska farmacie : casopis Ceske farmaceuticke spolecnosti a Slovenske farmaceuticke spolecnosti 20050301
Spectrofluorimetric study of the charge-transfer complexation of certain fluoroquinolones with 7,7,8,8-tetracyanoquinodimethane. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050101
Spectroscopic and voltammetric studies of pefloxacin bound to calf thymus double-stranded DNA. Analytical and bioanalytical chemistry 20050101
A comparison of effects of fluoroquinolones on fracture healing (an experimental study in rats). Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES 20050101
Outcome of infections due to pandrug-resistant (PDR) Gram-negative bacteria. BMC infectious diseases 20050101
The bacteriology of diabetic foot ulcers in Port Harcourt, Nigeria. Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria 20050101
Flow-injection electrogenerated chemiluminescence determination of fluoroquinolones based on its sensitizing effect. Luminescence : the journal of biological and chemical luminescence 20050101
[Properties of the Burkholderia pseudomallei insertional mutants deficient in membrane proteins production]. Molekuliarnaia genetika, mikrobiologiia i virusologiia 20050101
Multiresidue determination of eleven quinolones in milk by liquid chromatography with fluorescence detection. Journal of AOAC International 20050101
[Susceptibility to norfloxacin of some bacterial strains causing urinary infections]. Revista medico-chirurgicala a Societatii de Medici si Naturalisti din Iasi 20050101
[Activity of 22 antibacterials against O1 and O139 serogroup Vibrio cholerae strains isolated from humans within 1927-2005 in various regions of the world]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20050101
[Cholera in Rio Grande do Norte State--Brazil: sorology and sensitivity of Vibrio cholerae to different antimicrobials]. Acta cirurgica brasileira 20050101
[The use of fluoroquinolone plasma levels by physicians]. Presse medicale (Paris, France : 1983) 20041204
A clinical trial of pefloxacin and ofloxacin in lepromatous leprosy. Leprosy review 20041201
Isolation of E. coli from foam and effects of fluoroquinolones on E. coli and foam production in male Japanese quail. Theriogenology 20041101
Models for time-varying covariates in population pharmacokinetic-pharmacodynamic analysis. British journal of clinical pharmacology 20041001
[Resistance to linezolid in Staphylococcus aureus before its release]. Pathologie-biologie 20041001
Fluoroquinolones in children: poorly defined risk of joint damage. Prescrire international 20041001
[Study on fluorescence characteristics of pefloxacin-La(III) complex and its application]. Guang pu xue yu guang pu fen xi = Guang pu 20040901
A three-way comparative study on the efficacy of twin sol to gel systems and marketed eye drops of pefloxacin mesylate. Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20040801
[A 4-year study of Pseudomonas aeruginosa susceptibility to antibiotics (1998-2001) in northern Lebanon]. Medecine et maladies infectieuses 20040701
[The fluorescence characteristics of micelle inclusion of pefloxacin and its application]. Guang pu xue yu guang pu fen xi = Guang pu 20040701
Antimicrobial resistance in commensal flora of pig farmers. Emerging infectious diseases 20040501
[Pharmacokinetics and dose adaptation of ofloxacine, pefloxacine and ciprofloxacine during haemodialysis and continuous ambulatory peritoneal dialysis]. Annales pharmaceutiques francaises 20040501
[Study on fluorescence characteristics of pefloxacin based on charge transfer reaction]. Guang pu xue yu guang pu fen xi = Guang pu 20040501
[Staphylococcus aureus bacteremia in the Dakar Fann University Hospital]. Medecine et maladies infectieuses 20040501
Mycobacterium tuberculosis DNA gyrase: interaction with quinolones and correlation with antimycobacterial drug activity. Antimicrobial agents and chemotherapy 20040401
Effects of acetyl salicylate and ibuprofen on fluoroquinolone MICs on Salmonella enterica serovar typhimurium in vitro. Journal of chemotherapy (Florence, Italy) 20040401
Mechanisms of pefloxacin-induced pain. Bulletin of experimental biology and medicine 20040401
Extension of the isobolographic approach to interactions studies between more than two drugs: illustration with the convulsant interaction between pefloxacin, norfloxacin, and theophylline in rats. Journal of pharmaceutical sciences 20040301
Changing patterns in sensitivity of causative organisms of septicaemia in children: the need for quinolones. African journal of medicine and medical sciences 20040301
In vitro discrimination of fluoroquinolones toxicity on tendon cells: involvement of oxidative stress. The Journal of pharmacology and experimental therapeutics 20040101
Effect of pefloxacin on the urinary excretion of rifampicin. American journal of therapeutics 20040101
Some plasma and saliva pharmacokinetics parameters of rifampicin in the presence of pefloxacin. American journal of therapeutics 20040101
Antibiotics for preventing recurrent urinary tract infection in non-pregnant women. The Cochrane database of systematic reviews 20040101
Prulifloxacin. Drugs 20040101
Primary lymphocutaneous nocardiosis in an immunocompetent patient. Annals of clinical microbiology and antimicrobials 20040101
Cost-effectiveness analysis of switching from intravenous to oral administration of antibiotics in elderly patients. Bratislavske lekarske listy 20040101
Light induced changes in quinolone levels in rat serum and tissues. European journal of drug metabolism and pharmacokinetics 20040101
The resistance of Pseudomonas aeruginosa strains to fluoroquinolone group of antibiotics. Indian journal of medical microbiology 20040101
Dose ranging pharmacokinetics and brain distribution of norfloxacin using microdialysis in rats. Journal of pharmaceutical sciences 20031201
Activity of combinations of ceftazidime, imipenem and pefloxacin against Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa. International journal of antimicrobial agents 20031201
X-ray powder diffraction patterns for certain fluoroquinolone antibiotic drugs. Acta pharmaceutica (Zagreb, Croatia) 20031201
Reappraisal with meta-analysis of the addition of Gram-positive prophylaxis to fluoroquinolone in neutropenic patients. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20031115
Spectrofluorometric determination of certain quinolone antibacterials using metal chelation. Talanta 20030727
Fluoroquinolone-associated tendinopathy: a critical review of the literature. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20030601
Pharmacokinetics and tissue penetration of pefloxacin plus metronidazole after administration as surgical prophylaxis in colorectal surgery. International journal of clinical pharmacology and therapeutics 20030601
Molecular epidemiology of ampicillin-resistant clinical isolates of Salmonella enterica serovar Typhimurium. International journal of medical microbiology : IJMM 20030601
Antimicrobial sensitivity pattern of organisms causing urinary tract infection in children with sickle cell anaemia in Ibadan, Nigeria. West African journal of medicine 20030601
Staphylococcus aureus carriage in selected communities and their antibiotic susceptibility patterns. The Medical journal of Malaysia 20030601
Determination of the antibiotic drug pefloxacin in bulk form, tablets and human serum using square wave cathodic adsorptive stripping voltammetry. Journal of pharmaceutical and biomedical analysis 20030410
The effect of nitric oxide combined with fluoroquinolones against Salmonella enterica serovar Typhimurium in vitro. Memorias do Instituto Oswaldo Cruz 20030401
[Study of filter-paper-substrate delay fluorescence of three quinolones]. Guang pu xue yu guang pu fen xi = Guang pu 20030401
A microarray-based antibiotic screen identifies a regulatory role for supercoiling in the osmotic stress response of Escherichia coli. Genome research 20030201
Activities of 13 quinolones by three susceptibility testing methods against a collection of Haemophilus influenzae isolates with different levels of susceptibility to ciprofloxacin: evidence for cross-resistance. The Journal of antimicrobial chemotherapy 20030101
Adverse drug reactions related to the use of fluoroquinolone antimicrobials: an analysis of spontaneous reports and fluoroquinolone consumption data from three italian regions. Drug safety 20030101
[Experience in using the new drug moxifloxacin (Avelox, 'Bayer', Germaniia) in urologic practice]. Urologiia (Moscow, Russia : 1999) 20030101
[Drug sensitivity of Ureaplasma urealyticum, persisting in patients with chronic inflammatory diseases of the urogenital tract]. Zhurnal mikrobiologii, epidemiologii, i immunobiologii 20030101
[Formation of virulent antigen-modified mutants (Fra-, Fra-Tox-) of plague bacteria resistant to rifampicin and quinolones]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20030101
[Enterobacterial susceptibility to antibiotics in northern Lebanon (1998-2001)]. Sante (Montrouge, France) 20030101
[Antibiotherapy in osteoarticular infections in children suffering from hemoglobinopathy in the University Teaching Hospital of Yopougon]. Sante (Montrouge, France) 20030101
Efficacy of pefloxacin in the treatment of patients with acute infectious diarrhoea. Clinical drug investigation 20030101
Y. enterocolitica gastroenteritis - a prospective study. Indian journal of medical microbiology 20030101
[Diagnosis and treatment of legionella pneumonia]. Pneumologie (Stuttgart, Germany) 20021101
[Tenotoxic potential of fluoroquinolones in the choice of surgical antibiotic prophylaxis in ophthalmology]. Journal francais d'ophtalmologie 20021101
Antibiotic sensitivity and resistance profile of the micro-organisms responsible for urinary tract infection observed in Kashmir, India. Journal of the Indian Medical Association 20021101
Pharmacokinetics and tissue distribution of intravenous pefloxacin for antibiotic prophylaxis in biliary surgery. Biopharmaceutics & drug disposition 20021001
Some pharmacokinetic parameters of pefloxacin in lactating goats. Veterinary research communications 20021001
Optimization and validation of a CZE method for rufloxacin hydrochloride determination in coated tablets. Journal of pharmaceutical and biomedical analysis 20020615
Differences in caffeine and paraxanthine metabolism between human and murine CYP1A2. Biochemical pharmacology 20020615
The choice of antibiotic in open fractures in a teaching hospital in a developing country. International journal of clinical practice 20020601
Spectrophotometric determination of enrofloxacin and pefloxacin through ion-pair complex formation. Journal of pharmaceutical and biomedical analysis 20020401
Bacterial resistance to quinolone antibiotics in Poland. Journal of veterinary medicine. B, Infectious diseases and veterinary public health 20020401
Susceptibility of Enterobacteriaceae to beta-lactam agents and fluoroquinolones: a 3-year survey in France. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20020401
Emergence and rapid spread of tetracycline-resistant Vibrio cholerae strains, Madagascar. Emerging infectious diseases 20020301
Mechanisms of resistance to fluoroquinolones in Coxiella burnetii. The Journal of antimicrobial chemotherapy 20020201
Ciprofloxacin induces apoptosis and inhibits proliferation of human colorectal carcinoma cells. British journal of cancer 20020201
Pharmacokinetics of pefloxacin in goats after intravenous or oral administration. Veterinary research communications 20020201
Spectrophotometric determination of ciprofloxacin, enrofloxacin and pefloxacin through charge transfer complex formation. Journal of pharmaceutical and biomedical analysis 20020101
Influence of CO(2) incubation on quinolone activity against Streptococcus pneumoniae and Haemophilus influenzae. Diagnostic microbiology and infectious disease 20020101
Important role of prodromal viral infections responsible for inhibition of xenobiotic metabolizing enzymes in the pathomechanism of idiopathic Reye's syndrome, Stevens-Johnson syndrome, autoimmune hepatitis, and hepatotoxicity of the therapeutic doses of acetaminophen used in genetically predisposed persons. American journal of therapeutics 20020101
Clinical role of protein binding of quinolones. Clinical pharmacokinetics 20020101
[Bacteriologic examination of gallbladder contents]. Medicinski pregled 20020101
[Pefloxacin in the treatment of patients with mucoviscidosis]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20020101
In vitro antimicrobial interactions of arthemeter with some 4-quinolones. Bollettino chimico farmaceutico 20020101
[On fluoroquinolones treatment safety in children (clinical, morphological and catamnesis data)]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20020101
Microbial isolates in open fractures seen in the accident and emergency unit of a teaching hospital in a developing country. West African journal of medicine 20020101
[Efficacy of some new antibiotics in treating experimental brucellosis]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20020101
[Pefloxacin (Abaktal)--efficacy in treating severe infections, optimization of treatment based on pharmacokinetic and pharmacodynamic parameters]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20020101
[Susceptibility to antibiotics of Ureaplasma urealiticum strains isolated at the primorye region]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20020101
[Ofloxacin efficacy in the prophylaxis and treatment of experimental plague due to antigen complete and defective strains of the pathogen]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20020101
[Efficacy of administration of 0.3% pefloxacin solution in the treatment of acute diffuse inflammation of the auditory canal]. Lijecnicki vjesnik 20020101
Quinolones and false-positive urine screening for opiates by immunoassay technology. JAMA 20011226
[Hemoptysis in a patient with post-obstructive pneumonia due to a broncholith]. Recenti progressi in medicina 20011201
[Tendinopathy associated with fluoroquinolones: individuals at risk, incriminated physiopathologic mechanisms, therapeutic management]. Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie 20011201
[The activity of four fluoroquinolones against strains of Pseudomonas aeruginosa with a different sensitivity pattern to ceftazidime and imipenem]. Enfermedades infecciosas y microbiologia clinica 20011101
Pharmacokinetics of fluoroquinolones in uncompensated cirrhosis: the significance of penetration in the ascitic fluid. International journal of antimicrobial agents 20011101
Retrospective analysis of drug-induced urticaria and angioedema: a survey of 2287 patients. Immunopharmacology and immunotoxicology 20011101
In vitro selection of allosteric ribozymes: theory and experimental validation. Journal of molecular biology 20011005
Trends in quinolone susceptibility of Enterobacteriaceae among inpatients of a large university hospital: 1992-98. Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20011001
[Comparative study of the bacteriostatic and bactericidal activity of levofloxacin against Pasteurella strains isolated from man]. Pathologie-biologie 20011001
Comparison of minimum inhibitory concentration values for fluoroquinolones against Escherichia coli causing urinary tract infection in both hospitalized patients and outpatients. Saudi medical journal 20011001
[Study of pefloxacin concentration in blood and sputum in the aged pneumonia patients with impairment of renal function]. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20011001
Cognitive toxicity of drugs used in the elderly. Dialogues in clinical neuroscience 20010901
Pefloxacin and ciprofloxacin increase UVA-induced edema and immune suppression. Photodermatology, photoimmunology & photomedicine 20010801
Interaction between biofilms formed by Staphylococcus epidermidis and quinolones. Diagnostic microbiology and infectious disease 20010701
[Application of new strategies in the treatment of patients with purulent sepsis complications]. Klinichna khirurhiia 20010701
Tendon disorders attributed to fluoroquinolones: a study on 42 spontaneous reports in the period 1988 to 1998. Arthritis and rheumatism 20010601
In vitro susceptibility to 15 antibiotics of vibrios isolated from penaeid shrimps in Northwestern Mexico. International journal of antimicrobial agents 20010501
[An experimental study on the release of endotoxin from gram negative bacteria induced by antibiotics]. Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20010401
Treatment of focal segmental glomerulosclerosis. Current opinion in nephrology and hypertension 20010301
Pharmacokinetics of pefloxacin and its interaction with cyclosporin A, a P-glycoprotein modulator, in rat blood, brain and bile, using simultaneous microdialysis. British journal of pharmacology 20010301
Pharmacokinetics of intravenously administered pefloxacin in the prostate; perspectives for its application in surgical prophylaxis. International journal of antimicrobial agents 20010301
[Effect of subinhibitory levels of aminoglycosides and fluoroquinolines on hydrophobicity and motility of Serratia marcescens]. Epidemiologie, mikrobiologie, imunologie : casopis Spolecnosti pro epidemiologii a mikrobiologii Ceske lekarske spolecnosti J.E. Purkyne 20010201
[Antibiotic resistance of Staphylococcus aureus in urban experience: 6 month study in Aquitaine]. Pathologie-biologie 20010201
Selective separation and simultaneous determination of trace levels of five types of fluorinated quinolone drugs by thin-layer chromatography/fluorescence densitometry. Journal of AOAC International 20010101
Occurrence of variants with temperature-dependent susceptibility (TDS) to antibiotics among Stenotrophomonas maltophilia clinical strains. Folia microbiologica 20010101
[Comparative efficacy and safety of ciprofloxacin, ofloxacin, and pefloxacin in treatment of respiratory infections in children with cystic fibrosis]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20010101
History of quinolones and their side effects. Chemotherapy 20010101
Comparison of side effects of levofloxacin versus other fluoroquinolones. Chemotherapy 20010101
Evidence of different profiles of side effects and drug-drug interactions among the quinolones--the pharmacokinetic standpoint. Chemotherapy 20010101
[Effect of pefloxacin on immune response]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20010101
[Pefloxacin (abactal) efficacy in severe pneumonia]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20010101
[Efficacy of pefoxacin (abactal) in the complex treatment of patients with pancreonecrosis]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20010101
Studies on the significance of positive bacterial semen cultures in male fertility in Nigeria. International journal of fertility and women's medicine 20010101
Eradicative effect of cotrimoxazole and quinolones on non-typhoid salmonellae. Bratislavske lekarske listy 20010101
Comparative in-vitro activities of commonly available quinolones and other antibiotics on bacterial isolates in Ibadan, Nigeria. African journal of medicine and medical sciences 20010101
Prediction of quinolone activity against Mycobacterium avium by molecular topology and virtual computational screening. Antimicrobial agents and chemotherapy 20001001
Anti-toxoplasma activities of 24 quinolones and fluoroquinolones in vitro: prediction of activity by molecular topology and virtual computational techniques. Antimicrobial agents and chemotherapy 20001001
Pefloxacin in steroid dependent and resistant idiopathic nephrotic syndrome. Journal of nephrology 20000101
Purification and inhibition by quinolones of DNA gyrases from Mycobacterium avium, Mycobacterium smegmatis and Mycobacterium fortuitum bv. peregrinum. Microbiology (Reading, England) 19990901
The 2-pyridone antibacterial agents: 8-position modifications. Current pharmaceutical design 19990701
A new approach for early assessment of the epileptogenic potential of quinolones. Antimicrobial agents and chemotherapy 19981001
Correlation between quinolone susceptibility patterns and sequences in the A and B subunits of DNA gyrase in mycobacteria. Antimicrobial agents and chemotherapy 19980801
[Benign intracranial hypertension after treatment with pefloxacin]. Archives de pediatrie : organe officiel de la Societe francaise de pediatrie 19980801
Fluoroquinolones: a new treatment for tuberculosis? The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 19980401
Interaction between pefloxacin and aminophylline in genetically epilepsy-prone rats. The Journal of pharmacy and pharmacology 19971001
Pharmacokinetic-pharmacodynamic contributions to the convulsant activity of pefloxacin and norfloxacin in rats. The Journal of pharmacology and experimental therapeutics 19970201
Pefloxacin in adriamycin induced nephrotic syndrome in the rat. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 19970201
[Surgically treated chronic bilateral Achilles tendon disease, without spontaneous rupture, caused by perfloxacin]. Presse medicale (Paris, France : 1983) 19960629
An acute psychotic disorder caused by pefloxacin: a case report. Progress in neuro-psychopharmacology & biological psychiatry 19960201
Clinical and microbiological evaluation of pefloxacin in lower respiratory tract infections. The Journal of international medical research 19960101
New drugs for tuberculosis. The European respiratory journal. Supplement 19950901
Comparative in vitro activity of fluoroquinolones against Mycobacterium tuberculosis. The Indian journal of medical research 19950401
Preliminary study of the in vitro activity of irloxacin against mycobacteria. Chemotherapy 19950101
In vitro model to assess effect of antimicrobial agents on Encephalitozoon cuniculi. Antimicrobial agents and chemotherapy 19941001
Effects of some quinolones on imipenem-induced seizures in DBA/2 mice. General pharmacology 19940301
Grand mal seizures as a complication of treatment with pefloxacin in patients with cirrhosis. A report of three cases. Journal of hepatology 19931101
Activity of topoisomerase inhibitors against Pneumocystis carinii in vitro and in an inoculated mouse model. Antimicrobial agents and chemotherapy 19930701
Peripheral neuropathy associated with fluoroquinolones. Lancet (London, England) 19920711
Multiple intra-articular treatment of rheumatoid arthritis: a randomized prospective study comparing rifamycin SV with pefloxacin. The Journal of international medical research 19920201
Use of fluoroquinolones for prophylaxis of murine Pneumocystis carinii pneumonia. Antimicrobial agents and chemotherapy 19920201
[Neurologic side effects of fluoroquinolones. Apropos of 9 cases concerning pefloxacin]. Therapie 19920101
Non-nephrotoxic empiric antimicrobial therapy in febrile neutropenic cancer patients. European journal of cancer (Oxford, England : 1990) 19920101
Activities of pefloxacin and ofloxacin against mycobacteria: in vitro and mouse experiments. Tubercle 19910301
Central nervous system toxicity of quinolones: human and animal findings. The Journal of antimicrobial chemotherapy 19901001
Pefloxacin: safety in man. The Journal of antimicrobial chemotherapy 19901001
Comparative in-vitro activities of ten fluoroquinolones and fusidic acid against Mycobacterium spp. The Journal of antimicrobial chemotherapy 19900901
Epileptic attacks associated with pefloxacin treatment in a patient on CAPD. Clinical nephrology 19890701
[In vitro determination of the sensitivity of mycobacteria to fluoroquinolones]. Pathologie-biologie 19890501
Comparative antimycobacterial activities of difloxacin, temafloxacin, enoxacin, pefloxacin, reference fluoroquinolones, and a new macrolide, clarithromycin. Antimicrobial agents and chemotherapy 19890401
Mycobacteria and the new quinolones. Antimicrobial agents and chemotherapy 19890101
Comparative in-vitro activity of fleroxacin and other 6-fluoroquinolones against mycobacteria. The Journal of antimicrobial chemotherapy 19881001
In vitro activity of pefloxacin compared with five other quinolones on nalidixic acid-resistant proteae species. Chemioterapia : international journal of the Mediterranean Society of Chemotherapy 19881001
Neurological toxicity related to pefloxacin. The Journal of antimicrobial chemotherapy 19880601
Efficacy of pefloxacin-fosfomycin in experimental endocarditis caused by methicillin-resistant Staphylococcus aureus. Antimicrobial agents and chemotherapy 19880601
Activity of five fluoroquinolones against Mycobacterium avium-intracellulare complex and M. xenopi. Annales de l'Institut Pasteur. Microbiology 19880101
In vitro activity of five new quinolones against cultivable mycobacteria. European journal of clinical microbiology 19871001
In vitro activity of four fluoroquinolones against eighty-six isolates of mycobacteria. European journal of clinical microbiology 19871001
Critical risk/benefit analysis of pefloxacine use in children under 15 years--the problem of arthralgias. International journal of clinical pharmacology, therapy, and toxicology 19870601
Comparative in-vitro activity of five fluoroquinolones against mycobacteria. The Journal of antimicrobial chemotherapy 19870501
Properties