Home Sulfos Phenol,3-[[(4,5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino]-,monomethanesulfonate (salt)

Phenol,3-[[(4,5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino]-,monomethanesulfonate (salt)

CAS No.:
65-28-1
Catalog Number:
AG00IBFO
Molecular Formula:
C18H23N3O4S
Molecular Weight:
377.4579
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25mg
>98%(HPLC)
In Stock USA
United States
$47
- +
100mg
>98%(HPLC)
In Stock USA
United States
$99
- +
Product Description
Catalog Number:
AG00IBFO
Chemical Name:
Phenol,3-[[(4,5-dihydro-1H-imidazol-2-yl)methyl](4-methylphenyl)amino]-,monomethanesulfonate (salt)
CAS Number:
65-28-1
Molecular Formula:
C18H23N3O4S
Molecular Weight:
377.4579
MDL Number:
MFCD00134201
IUPAC Name:
3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid
InChI:
InChI=1S/C17H19N3O.CH4O3S/c1-13-5-7-14(8-6-13)20(12-17-18-9-10-19-17)15-3-2-4-16(21)11-15;1-5(2,3)4/h2-8,11,21H,9-10,12H2,1H3,(H,18,19);1H3,(H,2,3,4)
InChI Key:
OGIYDFVHFQEFKQ-UHFFFAOYSA-N
SMILES:
CS(=O)(=O)O.Cc1ccc(cc1)N(c1cccc(c1)O)CC1=NCCN1
EC Number:
200-604-6
UNII:
Y7543E5K9T
Properties
Complexity:
456  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
377.141g/mol
Formal Charge:
0
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
377.459g/mol
Monoisotopic Mass:
377.141g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
111A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
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Effect of adrenergic antagonists during phenylephrine stimulation of the mandibular gland of red kangaroos, Macropus rufus. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20020701
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The role of the sympathetic efferents in endotoxin-induced localized inflammatory hyperalgesia and cytokine upregulation. Neuropharmacology 20020501
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Enhanced contribution of NO to exercise-induced coronary responses after alpha-adrenergic receptor blockade. American journal of physiology. Heart and circulatory physiology 20020201
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Central regulation of photosensitive membrane turnover in the lateral eye of Limulus. I. Octopamine primes the retina for daily transient rhabdom shedding. Visual neuroscience 20020101
Effects of insulin on coronary blood flow in anesthetized pigs. Journal of vascular research 20020101
[Regulation of oxidative phosphorylation by liver mitochondria receptors after adaptation by rats to periodic normal pressure and acute hypoxia]. Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20020101
Centrally applied atrial natriuretic factor diminishes bile secretion in the rat. Regulatory peptides 20011215
Desensitization of insulin secretory response to imidazolines, tolbutamide, and quinine. I. Secretory and morphological studies. Biochemical pharmacology 20011215
Desensitization of insulin secretory response to imidazolines, tolbutamide, and quinine. II. Electrophysiological and fluorimetric studies. Biochemical pharmacology 20011215
Roles of norepinephrine and ATP in sympathetically evoked vasoconstriction in rat tail and hindlimb in vivo. American journal of physiology. Heart and circulatory physiology 20011201
Effects of regional phentolamine on hypoxic vasodilatation in healthy humans. The Journal of physiology 20011201
Activation of central melanocortin receptors by MT-II increases cavernosal pressure in rabbits by the neuronal release of NO. British journal of pharmacology 20011201
In vitro and in vivo impairment of alpha2-adrenergic receptor-dependent antilipolysis by fatty acids in human adipose tissue. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20011201
Effect of alpha-adrenoceptor blockade on the 0.4 Hz sympathetic rhythm in conscious rats. Clinical and experimental pharmacology & physiology 20011201
Influence of nitric oxide synthase and adrenergic inhibition on adenosine-induced myocardial hyperemia. Circulation 20011106
Neurotransmitters in the thalamus relaying visceral input to the insular cortex in the rat. American journal of physiology. Regulatory, integrative and comparative physiology 20011101
Reductions in basal limb blood flow and vascular conductance with human ageing: role for augmented alpha-adrenergic vasoconstriction. The Journal of physiology 20011101
Catecholamines abrogate antimitogenic effects of 2-hydroxyestradiol on human aortic vascular smooth muscle cells. Arteriosclerosis, thrombosis, and vascular biology 20011101
Changes in blood glucose and plasma insulin levels induced by bradykinin in anaesthetized rats. British journal of pharmacology 20011101
Epinephrine-induced digital ischemia relieved by phentolamine. Plastic and reconstructive surgery 20011101
Studies of the toxic effects of norepinephrine on isolated cardiomyocytes of guinea-pigs. Arzneimittel-Forschung 20011101
Adiponectin gene expression is inhibited by beta-adrenergic stimulation via protein kinase A in 3T3-L1 adipocytes. FEBS letters 20011026
Differential responses to ATPgammaS in the mesenteric and hindlimb vascular bed of the cat. Life sciences 20011012
Lack of alpha(2)-adrenergic antilipolytic effect during exercise in subcutaneous adipose tissue of trained men. Journal of applied physiology (Bethesda, Md. : 1985) 20011001
Synergistic effects of sildenafil on relaxation of rabbit and rat cavernosal smooth muscles when combined with various vasoactive agents. BJU international 20011001
Norepinephrine inhibits energy metabolism of human peripheral blood mononuclear cells via adrenergic receptors. Bioscience reports 20011001
Effect of sustained adrenergic receptors stimulation and blockade on lactate threshold in rats. The Journal of sports medicine and physical fitness 20010901
Effects of haloperidol and phentolamine on the crustacean cardiac ganglion. Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20010901
Troglitazone enhances glucose uptake induced by alpha-adrenoceptor stimulation via phosphatidylinositol 3-kinase in rat heart. Clinical and experimental pharmacology & physiology 20010901
[Diagnosis and assessment of pain]. Nihon rinsho. Japanese journal of clinical medicine 20010901
Characterization of alpha-adrenoceptor subtypes in smooth muscle of equine ileum. American journal of veterinary research 20010901
Adrenergic and endothelin B receptor-dependent hypertension in dopamine receptor type-2 knockout mice. Hypertension (Dallas, Tex. : 1979) 20010901
Effect of T-type selective calcium antagonist on renal microcirculation: studies in the isolated perfused hydronephrotic kidney. Hypertension (Dallas, Tex. : 1979) 20010901
Effects of pharmacological adrenergic and vagal modulation on fractal heart rate dynamics. Clinical physiology (Oxford, England) 20010901
The involvement of bradykinin in adrenaline-induced pulmonary edema in rats. Journal of medical and dental sciences 20010901
Molecular cloning and functional expression of the guinea pig alpha(1a)-adrenoceptor. European journal of pharmacology 20010831
Mechanisms of the renal vasodilation caused by insulin in anesthetized pigs. Life sciences 20010824
Synthesis and evaluation of 4-fluoro-8-substituted-2,3,4,5-tetrahydro-1H-2-benzazapines as selective inhibitors of phenylethanolamine N-methyltransferase versus the alpha(2)-adrenoceptor. Journal of medicinal chemistry 20010816
The value of sildenafil as mode of stimulation in pharmaco-penile duplex ultrasonography. International journal of impotence research 20010801
A conscious-rabbit model to study vardenafil hydrochloride and other agents that influence penile erection. International journal of impotence research 20010801
Presynaptic autoreceptors in the third decade: focus on alpha2-adrenoceptors. Journal of neurochemistry 20010801
Phentolamine suppresses the increase in arteriolar vasomotion frequency due to systemic hypoxia in hamster skeletal muscle microcirculation. Autonomic neuroscience : basic & clinical 20010720
A possible indirect sympathomimetic action of metformin in the arterial vessel wall of spontanously hypertensive rats. Life sciences 20010720
Intracavernous injection in the treatment of erectile dysfunction after radical prostatectomy: an observational study. Sao Paulo medical journal = Revista paulista de medicina 20010705
Gustatory-salivary reflexes induce non-adrenergic, non-cholinergic acinar degranulation in the rat parotid gland. Experimental physiology 20010701
Adrenergic vasoconstrictor activity in the cerebral circulation after inhibition of nitric oxide synthesis in conscious goats. Autonomic neuroscience : basic & clinical 20010620
Secondary somatosensory cortex stimulation facilitates the antinociceptive effect of the NO synthase inhibitor through suppression of spinal nociceptive neurons in the rat. Brain research 20010608
Ecstasy induced acute myocardial infarction. Heart (British Cardiac Society) 20010601
alpha-1 and alpha-2 Adrenergic antagonists relieve thermal hyperalgesia in experimental mononeuropathy from chronic constriction injury. Anesthesia and analgesia 20010601
Immunoaffinity purification and reconstitution of human alpha(2)-adrenergic receptor subtype C2 into phospholipid vesicles. Protein expression and purification 20010601
Pharmacological identification of the major subtypes of adrenoceptors involved in the canine external carotid vasoconstrictor effects of adrenaline and noradrenaline. Life sciences 20010601
Intracavernous injections: still the gold standard for treatment of erectile dysfunction in elderly men. International journal of impotence research 20010601
Paradoxical increase in microvascular resistance during tachycardia downstream from a severe stenosis in patients with coronary artery disease : reversal by angioplasty. Circulation 20010515
Responsiveness of canine bronchial vasculature to excitatory stimuli and to cooling. American journal of physiology. Lung cellular and molecular physiology 20010501
beta-Receptor agonist activity of phenylephrine in the human forearm. Journal of applied physiology (Bethesda, Md. : 1985) 20010501
Intracavernosal injection and intraurethral therapy for erectile dysfunction. The Urologic clinics of North America 20010501
Microinjection of arginine vasopressin into the central nucleus of amygdala suppressed nociceptive jaw opening reflex in freely moving rats. Brain research bulletin 20010501
[Response to intracavernous administration of 3 different drugs in the same group of patients with erectile dysfunction]. Archivos espanoles de urologia 20010501
Localisation and neural control of the release of calcitonin gene-related peptide (CGRP) from the isolated perfused porcine ileum. Regulatory peptides 20010420
A-85380 and epibatidine each interact with disparate spinal nicotinic receptor subtypes to achieve analgesia and nociception. The Journal of pharmacology and experimental therapeutics 20010401
Catecholamines play a role in the production of interleukin-6 and interleukin-1alpha in unburned skin after burn injury in mice. Critical care medicine 20010401
Role of the alpha(1)- and alpha(2)-adrenoceptors of the paraventricular nucleus on the water and salt intake, renal excretion, and arterial pressure induced by angiotensin II injection into the medial septal area. Brain research bulletin 20010401
Effects of heat exposure on adrenergic modulation of insulin and glucagon secretion in sheep. Endocrine journal 20010401
Modulation of feeding and drinking behaviour by catecholamines injected into nucleus caudatus in rats. Indian journal of physiology and pharmacology 20010401
Aviptadil (Senatek). Current opinion in investigational drugs (London, England : 2000) 20010401
Mechanical responses evoked by nerve stimulation in gastric muscles of mouse lacking inositol trisphosphate receptor. Autonomic neuroscience : basic & clinical 20010323
Inhibition by L-3,4-dihydroxyphenylalanine of hippocampal CA1 neurons with facilitation of noradrenaline and gamma-aminobutyric acid release. European journal of pharmacology 20010302
Acute pressor actions of ouabain do not enhance the actions of phenylephrine or norepinephrine in anesthetized rats. Journal of cardiovascular pharmacology 20010301
Combination of phentolamine and L-arginine or sildenafil synergistically improves neurogenic relaxation of rabbit corpus cavernosum smooth muscle. Urology 20010301
Endotoxin inhibits gastric emptying in rats via a capsaicin-sensitive afferent pathway. Naunyn-Schmiedeberg's archives of pharmacology 20010301
Depletion of brown fat norepinephrine content by acute cold exposure and adrenoceptor blockade. Pharmacology, biochemistry, and behavior 20010301
Sympathetic control of nasal blood flow in the rat mediated by alpha(1)-adrenoceptors. European journal of pharmacology 20010216
Conducted vasoconstriction in rat mesenteric arterioles: role for dihydropyridine-insensitive Ca(2+) channels. American journal of physiology. Heart and circulatory physiology 20010201
Alpha2-adrenoceptors modulating neuronal serotonin release: a study in alpha2-adrenoceptor subtype-deficient mice. British journal of pharmacology 20010201
Periovulatory changes in catfish ovarian oestradiol-17beta, oestrogen-2-hydroxylase and catechol-O-methyltransferase during GnRH analogue-induced ovulation and in vitro induction of oocyte maturation by catecholoestrogens. The Journal of endocrinology 20010201
Imidazolines inhibit secretory responses of rat colonic mucosa to calcium-dependent but not cyclic AMP-dependent secretagogues. The Journal of pharmacy and pharmacology 20010201
Vasomax for the treatment of male erectile dysfunction. World journal of urology 20010201
Differences in parasympathetic vasodilator and salivary responses in the cat submandibular gland between lingual and chorda-lingual nerve stimulation. Journal of dental research 20010201
Phentolamine mesylate relaxes rabbit corpus cavernosum by a nonadrenergic, noncholinergic mechanism. Fundamental & clinical pharmacology 20010201
Unexpected and pronounced antinociceptive synergy between spinal acetaminophen (paracetamol) and phentolamine. European journal of pharmacology 20010126
Phentolamine inhibits exocytosis of glucagon by Gi2 protein-dependent activation of calcineurin in rat pancreatic alpha -cells. The Journal of biological chemistry 20010112
Frequency dependent alpha(2)-adrenoceptor mediated modulation of excitatory junction potentials in guinea-pig mesenteric artery. European journal of pharmacology 20010105
Evidence of alpha-adrenoceptor-mediated chronotropic action in children. Pediatric cardiology 20010101
Electrical activation of endothelium evokes vasodilation and hyperpolarization along hamster feed arteries. American journal of physiology. Heart and circulatory physiology 20010101
Activation of extracellular signal-regulated kinases, NF-kappa B, and cyclic adenosine 5'-monophosphate response element-binding protein in lung neutrophils occurs by differing mechanisms after hemorrhage or endotoxemia. Journal of immunology (Baltimore, Md. : 1950) 20010101
In vivo demonstration of alpha(1A)-adrenoceptor subtype selectivity of KMD-3213 in rat tissues. The Journal of pharmacology and experimental therapeutics 20010101
Assessment of autonomic cardiovascular indices in non-stationary data in rats. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 20010101
Enhanced Ca2+-induced contractions and attenuated alpha-adrenoceptor responses in resistance arteries from rats with congestive heart failure. European journal of heart failure 20010101
Different alpha1-adrenoceptor-induced inositol phosphate formation in the two portions of rat vas deferens. Naunyn-Schmiedeberg's archives of pharmacology 20010101
Alpha2-adrenoceptor-mediated inhibition of cultured sympathetic neurons: changes in alpha2A/D-adrenoceptor-deficient mice. Naunyn-Schmiedeberg's archives of pharmacology 20010101
[Effects of infrasound and noise on contractility of lymphatic vessels (an experimental study)]. Meditsina truda i promyshlennaia ekologiia 20010101
Effects of adrenergic agonists and antagonists on tetrodotoxin-induced nerve block. Regional anesthesia and pain medicine 20010101
Phentolamine reduces myocardial injury and mortality in a rat model of phenylpropanolamine poisoning. Journal of toxicology. Clinical toxicology 20010101
Nisoxetine infusion into the olfactory bulb enhances the capacity for male rats to identify conspecifics. Neuroscience 20010101
Phentolamine use in a neonate for the prevention of dermal necrosis caused by dopamine: a case report. Journal of perinatology : official journal of the California Perinatal Association 20010101
Role of the enteric nervous plexus in rectal motile activity: an experimental study. Journal of investigative surgery : the official journal of the Academy of Surgical Research 20010101
Effect of progesterone on peripheral blood flow in prepubertal female anesthetized pigs. Journal of vascular research 20010101
Lipopolysaccharide-induced tumor necrosis factor-alpha release is controlled by the central nervous system. Neuroimmunomodulation 20010101
Effect of adrenergic agonists and antagonists on renin release. Proceedings of the Western Pharmacology Society 20010101
A clinical comparative study on effects of intracavernous injection of sodium nitroprusside and papaverine/phentolamine in erectile dysfunction patients. Asian journal of andrology 20001201
Pharmacological examination of contractile responses of the guinea-pig isolated ileum produced by mu-opioid receptor antagonists in the presence of, and following exposure to, morphine. British journal of pharmacology 20001101
Cocaine-induced hypertension: role of the peripheral sympathetic system. Pharmacological research 19990801
Progressive treatment of erectile dysfunction with intracorporeal injections of different combinations of vasoactive agents. International journal of impotence research 19990201
Treating men with predominantly nonpsychogenic erectile dysfunction with intracavernosal vasoactive intestinal polypeptide and phentolamine mesylate in a novel auto-injector system: a multicentre double-blind placebo-controlled study. BJU international 19990201
Tizanidine protects mice against convulsions induced by lidocaine: involvement of alpha 2-adrenoceptors. Pharmacology & toxicology 19990101
Role of sympathetic nervous system in experimental hypertension and diabetes mellitus. Clinical and experimental hypertension (New York, N.Y. : 1993) 19990101
Effects of centrally of peripherally injected adrenomedullin on reserpine-induced gastric lesions. European journal of pharmacology 19981030
Transurethral alprostadil as therapy for patients who withdrew from or failed prior intracavernous injection therapy. Urology 19980501
The role of endogenous bradykinin in blood pressure homeostasis in spontaneously hypertensive rats. British journal of pharmacology 19960801
Spinal anesthesia attenuates myocardial ischemia during coronary artery spasm induced by intraaortic methacholine in rats. Acta anaesthesiologica Scandinavica 19950801
Effects of chronic NO synthase inhibition in rats on renin-angiotensin system and sympathetic nervous system. The American journal of physiology 19950601
Involvement of the sympathetic postganglionic neuron in capsaicin-induced secondary hyperalgesia in the rat. Neuroscience 19950301
Comparison of a mixture of papaverine, phentolamine and prostaglandin E1 with other intracavernous injections. European urology 19940101
[Effectiveness and safety of cavernous body auto-injection therapy with papaverine/phentolamine. Study group]. Der Urologe. Ausg. A 19931101
The involvement of noradrenaline, 5-hydroxytryptamine and acetylcholine in imipramine-induced seizures in mice. Experientia 19931015
Presynaptic alpha 2-autoreceptors in brain cortex: alpha 2D in the rat and alpha 2A in the rabbit. Naunyn-Schmiedeberg's archives of pharmacology 19930701
Sodium bicarbonate alleviates penile pain induced by intracavernous injections for erectile dysfunction. The Journal of urology 19930501
Neural mechanism of hypertension by nitric oxide synthase inhibitor in dogs. Hypertension (Dallas, Tex. : 1979) 19930101
Intracavernosal papaverine and phentolamine for the medical management of erectile dysfunction in a genitourinary clinic. International journal of STD & AIDS 19930101
Naloxone-induced bradycardia in pithed rats: evidence for an interaction with the peripheral sympathetic nervous system and alpha-2 adrenoceptors. The Journal of pharmacology and experimental therapeutics 19921201
Use of phentolamine for cocaine-induced myocardial ischemia. The New England journal of medicine 19920730
The role of intracavernous injection of vasoactive medications for the restoration of erection in spinal cord injured males: a three year follow up. Paraplegia 19920201
Long-term results of corpus cavernosum autoinjection therapy for chronic erectile dysfunction. Andrologia 19920101
[Long-term results of corpus cavernosum auto-injection therapy in treatment of patients with chronic erectile dysfunction]. Der Urologe. Ausg. A 19920101
An improved vasoactive drug combination for a pharmacological erection program. The Journal of urology 19911201
Pharmacologically induced erections among geriatric men. The Journal of urology 19911001
Treatment of pharmacological priapism with phenylephrine. The Journal of urology 19910801
Effects of selective adrenoceptor agonists and antagonists on aggressive behavior elicited by apomorphine, DL-dopa and fusaric acid in REM-sleep-deprived rats. Physiology & behavior 19910701
Features of the acute hypotensive action of carvedilol and its ameliorating effect on myocardial ischemia. Journal of cardiovascular pharmacology 19910101
Sexual, psychological, and marital impact of self-injection of papaverine and phentolamine: a long-term prospective study. Journal of sex & marital therapy 19910101
Intracavernous injection of prostaglandin E1 in combination with papaverine: enhanced effectiveness in comparison with papaverine plus phentolamine and prostaglandin E1 alone. The Journal of urology 19910101
[Intracavernous pharmacotherapy for organic impotence in the elderly]. Harefuah 19900801
Intracavernous injection therapy: analysis of results and complications. The Journal of urology 19900601
Cocaine-induced changes in perfusion pressure and bile flow in perfused rat livers. Biochemical pharmacology 19890701
Treatment of peripheral ischemia secondary to lidocaine containing epinephrine. Annals of plastic surgery 19890701
[Papaverine-induced priapism. Experiences with a new urologic emergency]. Deutsche medizinische Wochenschrift (1946) 19890210
Side effects of self-administration of intracavernous papaverine and phentolamine for the treatment of impotence. The Journal of urology 19890101
Efficiency and side effects of prostaglandin E1 in the treatment of erectile dysfunction. The Journal of urology 19880901
Alpha 2-adrenoceptor activity exerts dual control of coronary blood flow in canine coronary artery. The American journal of physiology 19880801
Therapeutic roles of intracavernosal papaverine. Cardiovascular and interventional radiology 19880801
Mid-term results of autoinjection therapy for erectile dysfunction. Urology 19880601
Prostaglandins inhibit endogenous pain control mechanisms by blocking transmission at spinal noradrenergic synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience 19880401
Involvement of beta 2-adrenoceptor-mediated mechanisms in the cardiovascular responses to alpha 1- and alpha 2-adrenoceptor antagonism in conscious, unrestrained, Long Evans and Brattleboro rats. British journal of pharmacology 19880101
Fibrosis of tunica albuginea: complication of long-term intracavernous pharmacological self-injection. The Journal of urology 19870801
Antagonism of cocaine-induced hepatotoxicity by the alpha adrenergic antagonists phentolamine and yohimbine. The Journal of pharmacology and experimental therapeutics 19870801
Pharmacological erection: diagnosis and treatment applications in 69 patients. The Journal of urology 19870701
Pharmacologic erection program for the treatment of male impotence. Southern medical journal 19870401
Enhanced stimulus-induced neurotransmitter overflow in epinephrine-induced hypertensive rats is not mediated by prejunctional beta-adrenoceptor activation. Journal of hypertension. Supplement : official journal of the International Society of Hypertension 19861201
Adrenergic control of lipolysis and metabolic responses in obesity. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 19861001
[Metaraminol--an antidote in corpus cavernosum autoinjection therapy-induced prolonged erection]. Der Urologe. Ausg. A 19860501
Ventricular tachycardia induced by clonidine withdrawal. British heart journal 19850601
Dissociation of epinephrine's hyperglycemic and anorectic effect. Physiology & behavior 19850301
[Hemodynamic and respiratory effects of phentolamine in pulmonary hypertension secondary to chronic obstructive syndrome]. Schweizerische medizinische Wochenschrift 19850119
Ketanserin: a possible tool for studying the role of serotonin in hypertension. Journal of cardiovascular pharmacology 19850101
The effect of peripherally administered GABA on noradrenaline-induced reflex vagal bradycardia in urethane anaesthetized rats. General pharmacology 19850101
Mechanisms of central prostaglandin E2 hypertension in conscious dogs, sheep, and calves. The American journal of physiology 19840801
In vitro and in vivo studies of 3,4-dihydro-6-[4-(3,4-dimethoxybenzoyl)-1-piperazinyl]-2(1H)- quinolinone (OPC-8212), a novel positive inotropic drug, in various animals. Arzneimittel-Forschung 19840101
Autonomic and baroreflex function after captopril in hypertension. American heart journal 19830601
A nonhuman primate model for evaluating the potential of antihypertensive drugs to cause orthostatic hypotension. Journal of pharmacological methods 19830501
Some functional changes in experimentally induced cardiac overload. Acta physiologica et pharmacologica Bulgarica 19830101
Examinations on contribution of bradykinin in the action of dopamine in circulatory system of rats. I. Influence of bradykinin in the action of dopamine on arterial blood pressure of rats. Archivum immunologiae et therapiae experimentalis 19830101
Urethane inhibits cardiovascular responses mediated by the stimulation of alpha-2 adrenoceptors in the rat. The Journal of pharmacology and experimental therapeutics 19821101
Receptor interactions of imidazolines. IX. Cirazoline is an alpha-1 adrenergic agonist and an alpha-2 adrenergic antagonist. The Journal of pharmacology and experimental therapeutics 19820701
The effects of cigarette smoke and nicotine on platelet thrombus formation in stenosed dog coronary arteries: inhibition with phentolamine. Circulation 19820301
Alpha-adrenoceptor blockade by phentolamine causes beta-adrenergic vasodilation by increased catecholamine release due to presynaptic alpha-blockade. Journal of cardiovascular pharmacology 19820101
Central cholinergic mechanisms in L-DOPA induced hyperactive urinary bladder of the rat. Urological research 19820101
Hypertensive crisis resulting from avocados and a MAO inhibitor. Drug intelligence & clinical pharmacy 19811101
Noninvasive assessment of load reduction in chronic congestive heart failure patients. Angiology 19810801
Plasma noradrenaline concentration and alpha-adrenoceptor-mediated vasoconstriction in normotensive and hypertensive man. Clinical science (London, England : 1979) 19810501
Mediation of renin release in essential hypertension by alpha-adrenoreceptors. Journal of cardiovascular pharmacology 19810101
Indomethacin and cerebrovascular permeability to albumin in acute hypertension and cerebral embolism in the rat. Experimental brain research 19810101
Effect of beta-receptor-blocking agents on cardiovascular structural changes in spontaneous and noradrenaline-induced hypertension in rats. Clinical science (London, England : 1979) 19801201
Effects of clonidine on canine cardiac neuroeffector structures controlling heart rate. British journal of pharmacology 19801001
the role of differential blockade of alpha-adrenergic agonists in chlorpromazine-induced hypotension. Archives internationales de pharmacodynamie et de therapie 19800901
Noradrenergic influences on sound-induced seizures. The Journal of pharmacology and experimental therapeutics 19800801
The role of alpha receptors in the facilitation of the chemoreflex and inhibition of the carotid occlusion reflex by clonidine. Clinical and experimental hypertension 19800101
Plasma noradrenaline correlates with alpha-adrenoreceptor-mediated vasoconstriction and blood pressure in patients with essential hypertension. Clinical science (London, England : 1979) 19791201
Effects of pretreatment with 6-hydroxydopamine or noradrenergic receptor blockers on the clonidine-induced distruption of conditioned avoidance responding. European journal of pharmacology 19790901
Chronic treatment with antidepressant drugs: potentiation of apomorphine-induced aggressive behaviour in rats. Neuroscience letters 19790801
Oral therapy with phentolamine in chronic congestive heart failure. Chest 19790401
Central action of narcotic analgesics. Part III. The role of endogenous noradrenaline in hyperactivity induced by morphine or fentanyl in mice. Polish journal of pharmacology and pharmacy 19780101
Evidence for separate peptide sequences related to the lipolytic and magnesium-accumulating activities of ACTH. Analogy with adrenergic receptors. Journal of medicinal chemistry 19770401
[Effect of several neuroleptic, adreno-, sympatho- and cholinolytic substances on the development of experimental cerebral edema induced by nicotine]. Farmakologiia i toksikologiia 19770101
Interaction of adrenergic antagonists with prostaglandin E2 and tetrahydrocannabinol in the eye. Investigative ophthalmology 19760201
Centrally mediated increased reflex vagal bradycardia after L-dopa in monoamine oxidase-inhibited anesthetized dogs. The Journal of pharmacology and experimental therapeutics 19760201
Paradoxical rise in blood pressure during propranolol treatment. British medical journal 19751213
Regional vascular influences on tail-cuff measurements of drug-induced changes in systolic pressure. Journal of applied physiology 19751101
Effects of phentolamine, dihydroergocristine and isoxsuprine on the blood pressure and heart rate in normotensive, hypotensive and hypertensive rats. Naunyn-Schmiedeberg's archives of pharmacology 19750101
Use of phentolamine in acute myocardial infarction associated with hypertension and left ventricular failure. Circulation 19730401
Pharmacology of AH 5158; a drug which blocks both - and -adrenoceptors. British journal of pharmacology 19720801
[Mechanism of the ventricular fibrillation following intravenous adrenaline administration under halothane anesthesia]. Kumamoto Igakkai zasshi. The Journal of the Kumamoto Medical Society 19710125
Monoamine oxidase inhibitors and L-dopa. British medical journal 19700815
Positive phentolamine test in hypertension induced by a nasal decongestant. The New England journal of medicine 19690417
[Mechanism of inversion by demethylimipramine of motor depression induced by tetrabenazine]. Farmakologiia i toksikologiia 19690101
A receptor mechanism for the inhibition of insulin release by epinephrine in man. The Journal of clinical investigation 19670101
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