Home Halogens 5,6-Dichlorobenzimidazole

5,6-Dichlorobenzimidazole

CAS No.:
6478-73-5
Catalog Number:
AG00IBEL
Molecular Formula:
C7H4Cl2N2
Molecular Weight:
187.0261
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1g
97%
In Stock USA
United States
$94
- +
5g
97%
In Stock USA
United States
$388
- +
10g
97%
In Stock USA
United States
$725
- +
25g
97%
In Stock USA
United States
$1400
- +
Product Description
Catalog Number:
AG00IBEL
Chemical Name:
5,6-Dichlorobenzimidazole
CAS Number:
6478-73-5
Molecular Formula:
C7H4Cl2N2
Molecular Weight:
187.0261
MDL Number:
MFCD00211325
IUPAC Name:
5,6-dichloro-1H-benzimidazole
InChI:
InChI=1S/C7H4Cl2N2/c8-4-1-6-7(2-5(4)9)11-3-10-6/h1-3H,(H,10,11)
InChI Key:
IPRDZAMUYMOJTA-UHFFFAOYSA-N
SMILES:
Clc1cc2[nH]cnc2cc1Cl
NSC Number:
326397
Properties
Complexity:
153  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
185.975g/mol
Formal Charge:
0
Heavy Atom Count:
11  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
187.023g/mol
Monoisotopic Mass:
185.975g/mol
Rotatable Bond Count:
0
Topological Polar Surface Area:
28.7A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.7  
Literature
Title Journal
SUMO modification of the neuroprotective protein TDP1 facilitates chromosomal single-strand break repair. Nature communications 20120313
Synthesis and biological evaluation of benzo[d]imidazole derivatives as potential anti-cancer agents. Bioorganic & medicinal chemistry letters 20120201
Paraoxonases-2 and -3 Are Important Defense Enzymes against Pseudomonas aeruginosa Virulence Factors due to Their Anti-Oxidative and Anti-Inflammatory Properties. Journal of lipids 20120101
Implication of the ERK pathway on the post-transcriptional regulation of VEGF mRNA stability. Methods in molecular biology (Clifton, N.J.) 20100101
Rates of in situ transcription and splicing in large human genes. Nature structural & molecular biology 20091101
Determination of benzimidazole- and bicyclic hydantoin-derived selective androgen receptor antagonists and agonists in human urine using LC-MS/MS. Analytical and bioanalytical chemistry 20080501
The polyglutamine-expanded protein ataxin-3 decreases bcl-2 mRNA stability. Biochemical and biophysical research communications 20080111
Identification of metabolites with anticancer properties by computational metabolomics. Molecular cancer 20080101
Selective androgen receptor modulators in preclinical and clinical development. Nuclear receptor signaling 20080101
Role of glucocorticoid receptor and CCAAT/enhancer-binding protein alpha in the feed-forward induction of 11beta-hydroxysteroid dehydrogenase type 1 expression by cortisol in human amnion fibroblasts. The Journal of endocrinology 20071101
Synthesis and SAR of potent and selective androgen receptor antagonists: 5,6-Dichloro-benzimidazole derivatives. Bioorganic & medicinal chemistry letters 20070201
Molecular modeling of some 1H-benzimidazole derivatives with biological activity against Entamoeba histolytica: a comparative molecular field analysis study. Bioorganic & medicinal chemistry 20070115
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Ligand-induced estrogen receptor alpha degradation by the proteasome: new actors? Nuclear receptor signaling 20060101
Intergenic transcription is not required in Th2 cells to maintain histone acetylation and transcriptional permissiveness at the Il4-Il13 locus. Journal of immunology (Baltimore, Md. : 1950) 20051215
Casein kinase II (CK2) enhances death-inducing signaling complex (DISC) activity in TRAIL-induced apoptosis in human colon carcinoma cell lines. Oncogene 20050317
Influence of casein kinase II in tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human rhabdomyosarcoma cells. Clinical cancer research : an official journal of the American Association for Cancer Research 20041001
Effects of macromolecule synthesis inhibitors on light-induced phase shift of the circadian rhythm in melatonin release from the cultured pineal organ of a teleost, ayu (Plecoglossus altivelis). Zoological science 20031101
Synthesis of photoactivable inhibitors of osteoclast vacuolar ATPase. Bioorganic & medicinal chemistry 20030515
Low density lipoproteins downregulate lysyl oxidase in vascular endothelial cells and the arterial wall. Arteriosclerosis, thrombosis, and vascular biology 20020901
Synthesis and antiparasitic activity of 1H-benzimidazole derivatives. Bioorganic & medicinal chemistry letters 20020819
Post-transcriptional regulation of the AT1 receptor mRNA. Identification of the mRNA binding motif and functional characterization. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010601
Up-regulation of cyclooxygenase-1 in neuroblastoma cell lines by retinoic acid and corticosteroids. Journal of neurochemistry 20010401
Properties