Home Sulfos 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,3,3-dimethyl-6-[[[[[[[3-(methylsulfonyl)-2-oxo-1-imidazolidinyl]carbonyl]amino]carbonyl]amino]phenylacetyl]amino]-7-oxo-, monosodium salt,[2S-[2a,5a,6b(S*)]]-

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,3,3-dimethyl-6-[[[[[[[3-(methylsulfonyl)-2-oxo-1-imidazolidinyl]carbonyl]amino]carbonyl]amino]phenylacetyl]amino]-7-oxo-, monosodium salt,[2S-[2a,5a,6b(S*)]]-

CAS No.:
59798-30-0
Catalog Number:
AG00IALY
Molecular Formula:
Molecular Weight:
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
100mg
97%
In Stock USA
United States
$78
- +
1g
97%
In Stock USA
United States
$135
- +
5g
97%
In Stock USA
United States
$508
- +
25g
97%
In Stock USA
United States
$1241
- +
Product Description
Catalog Number:
AG00IALY
Chemical Name:
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid,3,3-dimethyl-6-[[[[[[[3-(methylsulfonyl)-2-oxo-1-imidazolidinyl]carbonyl]amino]carbonyl]amino]phenylacetyl]amino]-7-oxo-, monosodium salt,[2S-[2a,5a,6b(S*)]]-
CAS Number:
59798-30-0
MDL Number:
MFCD07793332
IUPAC Name:
sodium;(2S,5R,6R)-3,3-dimethyl-6-[[(2R)-2-[(3-methylsulfonyl-2-oxoimidazolidine-1-carbonyl)amino]-2-phenylacetyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
InChI:
InChI=1S/C21H25N5O8S2.Na/c1-21(2)14(18(29)30)26-16(28)13(17(26)35-21)22-15(27)12(11-7-5-4-6-8-11)23-19(31)24-9-10-25(20(24)32)36(3,33)34;/h4-8,12-14,17H,9-10H2,1-3H3,(H,22,27)(H,23,31)(H,29,30);/q;+1/p-1/t12-,13-,14+,17-;/m1./s1
InChI Key:
GTGQRSIMEUWHPA-ZBJAFUORSA-M
EC Number:
255-640-5
UNII:
RX227TP94U
Properties
Complexity:
1090  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
4  
Defined Bond Stereocenter Count:
0
Exact Mass:
561.096g/mol
Formal Charge:
0
Heavy Atom Count:
37  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
561.56g/mol
Monoisotopic Mass:
561.096g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
210A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
Title Journal
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). PLoS computational biology 20111201
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals 20101201
Effects of prophylactic antibiotic therapy with mezlocillin plus sulbactam on the incidence and height of fever after severe acute ischemic stroke: the Mannheim infection in stroke study (MISS). Stroke 20080401
Antibiotic therapy for preterm premature rupture of membranes - results of a multicenter study. Journal of perinatal medicine 20060101
Clinical determinants for the recovery of fungal and mezlocillin-resistant pathogens from bile specimens. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020401
[Analysis of prophylactic antibiotics for cesarean section]. Zhonghua fu chan ke za zhi 20020101
Efficacy of oral ofloxacin for single-dose perioperative prophylaxis in general surgery--a controlled randomized clinical study. Langenbeck's archives of surgery 20011101
Pharmacokinetic basis for oral perioperative prophylaxis with ofloxacin in general surgery. Infection 20010801
In vitro activity of mezlocillin, meropenem, aztreonam, vancomycin, teicoplanin, ribostamycin and fusidic acid against Borrelia burgdorferi. International journal of antimicrobial agents 20010301
Treatment of accidental high dose intraventricular mezlocillin application by cerebrospinal fluid exchange. Journal of neurology, neurosurgery, and psychiatry 19980301
A prospective randomized trial of ceftazidime versus netilmicin plus mezlocillin in the empirical therapy of presumed sepsis in cirrhotic patients. Hepatology (Baltimore, Md.) 19970401
Pharmacokinetics of mezlocillin and sulbactam under continuous veno-venous hemodialysis (CVVHD) in intensive care patients with acute renal failure. European journal of clinical pharmacology 19970101
Severe cholestatic jaundice caused by mezlocillin. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 19920701
A controlled study of the nephrotoxicity of mezlocillin and gentamicin plus ampicillin in the neonate. The Journal of pediatrics 19871201
Acute interstitial nephritis associated with mezlocillin, nafcillin, and gentamicin treatment for Pseudomonas infection. Archives of internal medicine 19850701
Properties