Home Sulfos 1-Naphthalenesulfonic acid,3,3'-[[1,1'-biphenyl]-4,4'-diylbis(azo)]bis[4-amino-, disodium salt

1-Naphthalenesulfonic acid,3,3'-[[1,1'-biphenyl]-4,4'-diylbis(azo)]bis[4-amino-, disodium salt

CAS No.:
573-58-0
Catalog Number:
AG00IA7N
Molecular Formula:
C32H22N6Na2O6S2
Molecular Weight:
696.6632
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25g
In Stock USA
United States
$41
- +
100g
In Stock USA
United States
$75
- +
500g
In Stock USA
United States
$225
- +
Product Description
Catalog Number:
AG00IA7N
Chemical Name:
1-Naphthalenesulfonic acid,3,3'-[[1,1'-biphenyl]-4,4'-diylbis(azo)]bis[4-amino-, disodium salt
CAS Number:
573-58-0
Molecular Formula:
C32H22N6Na2O6S2
Molecular Weight:
696.6632
MDL Number:
MFCD00004028
IUPAC Name:
disodium;4-amino-3-[[4-[4-[(1-amino-4-sulfonatonaphthalen-2-yl)diazenyl]phenyl]phenyl]diazenyl]naphthalene-1-sulfonate
InChI:
InChI=1S/C32H24N6O6S2.2Na/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34;;/h1-18H,33-34H2,(H,39,40,41)(H,42,43,44);;/q;2*+1/p-2
InChI Key:
IQFVPQOLBLOTPF-UHFFFAOYSA-L
SMILES:
Nc1c(/N=N/c2ccc(cc2)c2ccc(cc2)/N=N/c2cc(c3c(c2N)cccc3)S(=O)(=O)[O-])cc(c2c1cccc2)S(=O)(=O)[O-].[Na+].[Na+]
EC Number:
209-358-4
UNII:
3U05FHG59S
Properties
Complexity:
1180  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
696.084g/mol
Formal Charge:
0
Heavy Atom Count:
48  
Hydrogen Bond Acceptor Count:
12  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
696.664g/mol
Monoisotopic Mass:
696.084g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
233A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
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Inhibition of amyloid fibril formation of beta-amyloid peptides via the amphiphilic surfactants. Biochimica et biophysica acta 20050925
Effects of the sequence and size of non-polar residues on self-assembly of amphiphilic peptides. International journal of biological macromolecules 20050915
Amyloid-like fibril formation of co-chaperonin GroES: nucleation and extension prefer different degrees of molecular compactness. Journal of molecular biology 20050902
Histochemical and topo-optical investigations on tissue-isolated and in vitro amyloid fibrils. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20050901
Evidence for a mechanism of amyloid formation involving molecular reorganisation within native-like precursor aggregates. Journal of molecular biology 20050826
Aggregation and porin-like channel activity of a beta sheet peptide. Biochemistry 20050802
Beta-amyloid peptides stimulate endozepine biosynthesis in cultured rat astrocytes. Journal of neurochemistry 20050801
'Nature-inspired' drug-protein complexes as inhibitors of Abeta aggregation. Biochemical Society transactions 20050801
Thermostable direct hemolysin of Vibrio parahaemolyticus is a bacterial reversible amyloid toxin. Biochemistry 20050726
Transformation of diffuse beta-amyloid precursor protein and beta-amyloid deposits to plaques in the thalamus after transient occlusion of the middle cerebral artery in rats. Stroke 20050701
Oxidation of low-density lipoproteins induces amyloid-like structures that are recognized by macrophages. Biochemistry 20050628
Delineation of positron emission tomography imaging agent binding sites on beta-amyloid peptide fibrils. The Journal of biological chemistry 20050624
Candida albicans Pmr1p, a secretory pathway P-type Ca2+/Mn2+-ATPase, is required for glycosylation and virulence. The Journal of biological chemistry 20050617
Spectroscopic studies of the intermolecular interactions of Congo red and tinopal CBS with modified cellulose fibers. Langmuir : the ACS journal of surfaces and colloids 20050607
[Clinical features of patients with the pathological diagnosis of amyloidosis]. Revista medica de Chile 20050601
Biosorption of water-soluble dyes on magnetically modified Saccharomyces cerevisiae subsp. uvarum cells. Chemosphere 20050501
Biofilm formation, cellulose production, and curli biosynthesis by Salmonella originating from produce, animal, and clinical sources. Journal of food protection 20050501
Identification of neurite outgrowth active sites on the laminin alpha4 chain G domain. Biochemistry 20050419
Characterization of recombinant amyloidogenic chicken cystatin mutant I66Q expressed in yeast. Journal of biochemistry 20050401
Unfolding, aggregation, and seeded amyloid formation of lysine-58-cleaved beta 2-microglobulin. Biochemistry 20050322
Conjugated polyelectrolytes: conformation-sensitive optical probes for detection of amyloid fibril formation. Biochemistry 20050315
Effects of alkalinity and co-substrate on the performance of an upflow anaerobic sludge blanket (UASB) reactor through decolorization of Congo Red azo dye. Bioresource technology 20050301
Hsp20, a novel alpha-crystallin, prevents Abeta fibril formation and toxicity. Protein science : a publication of the Protein Society 20050301
Multiple ligand binding sites on A beta(1-40) fibrils. Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 20050301
Single-site mutations in a hyperthermophilic variant of the B1 domain of protein G result in self-assembled oligomers. Biochemistry 20050222
Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo. The Journal of biological chemistry 20050218
Attacking amyloid. The New England journal of medicine 20050217
Determination of nucleic acids at nanogram level using resonance light scattering technique with Congo Red. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20050114
Alzheimer's beta-amyloid: insights into fibril formation and structure from Congo red binding. Sub-cellular biochemistry 20050101
Time-lapse atomic force microscopy in the characterization of amyloid-like fibril assembly and oligomeric intermediates. Methods in molecular biology (Clifton, N.J.) 20050101
Histological staining of amyloid-beta in mouse brains. Methods in molecular biology (Clifton, N.J.) 20050101
Quantitative colorimetric analysis of aloe polysaccharides as a measure of Aloe vera quality in commercial products. Journal of AOAC International 20050101
Muscular amyloidoma presenting as inguinal masses in multiple myeloma. Scandinavian journal of rheumatology 20050101
Protective effect of zinc on amyloid-beta 25-35 and 1-40 mediated toxicity. Neurotoxicity research 20050101
A case report of dystrophic localized amyloidosis that developed in the left thigh. Pathology, research and practice 20050101
Beta-amyloid-derived pentapeptide RIIGLa inhibits Abeta(1-42) aggregation and toxicity. Biochemical and biophysical research communications 20041105
The search for biomarkers of aging: next stop INK4a/ARF locus. Science of aging knowledge environment : SAGE KE 20041103
Medicine. A wily recruiter in the battle against toxic beta amyloid aggregation. Science (New York, N.Y.) 20041029
Harnessing chaperones to generate small-molecule inhibitors of amyloid beta aggregation. Science (New York, N.Y.) 20041029
Synthesis of analogues of Congo red and evaluation of their anti-prion activity. Journal of medicinal chemistry 20041021
Amyloid fibril formation by a partially structured intermediate state of alpha-chymotrypsin. Journal of molecular biology 20040903
Cathepsin V, a novel and potent elastolytic activity expressed in activated macrophages. The Journal of biological chemistry 20040827
Formation of amyloid fibers triggered by phosphatidylserine-containing membranes. Biochemistry 20040817
Self-assembly, optical behavior, and permeability of a novel capsule based on an azo dye and polyelectrolytes. Chemistry (Weinheim an der Bergstrasse, Germany) 20040719
A severe form of amyloidotic polyneuropathy in a Costa Rican family with a rare transthyretin mutation (Glu54Lys). American journal of medical genetics. Part A 20040715
High pressure induces scrapie-like prion protein misfolding and amyloid fibril formation. Biochemistry 20040608
Structural characterization of the fibrillar form of the yeast Saccharomyces cerevisiae prion Ure2p. Biochemistry 20040504
Soluble Arctic amyloid beta protein inhibits hippocampal long-term potentiation in vivo. The European journal of neuroscience 20040501
[Therapeutic targets in polyglutamine diseases]. Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 20040501
Seeding specificity in amyloid growth induced by heterologous fibrils. The Journal of biological chemistry 20040423
The HPV16 E7 viral oncoprotein self-assembles into defined spherical oligomers. Biochemistry 20040330
Human amylin oligomer growth and fibril elongation define two distinct phases in amyloid formation. The Journal of biological chemistry 20040326
Peptide sequence and amyloid formation; molecular simulations and experimental study of a human islet amyloid polypeptide fragment and its analogs. Structure (London, England : 1993) 20040301
Pharmacokinetics and distribution of sodium 3,4-diaminonaphthalene-1-sulfonate, a Congo Red derivative active in inhibiting PrP(res) replication. The Journal of pharmacy and pharmacology 20040301
An engineered PrPsc-like molecule from the chimera of mammalian prion protein and yeast Ure2p prion-inducing domain. Acta biochimica et biophysica Sinica 20040201
Prevention by bovine milk against Helicobacter pylori-associated atrophic gastritis through its adherence inhibition. Hepato-gastroenterology 20040101
Imaging beta-amyloid plaques and neurofibrillary tangles in the aging human brain. Current pharmaceutical design 20040101
Decolorization of azo dyes under batch anaerobic and sequential anaerobic/aerobic conditions. Journal of environmental science and health. Part A, Toxic/hazardous substances & environmental engineering 20040101
Force-field parametrization and molecular dynamics simulations of Congo red. Journal of computer-aided molecular design 20040101
Evaluation of anti-prion activity of congo red and its derivatives in experimentally infected hamsters. Arzneimittel-Forschung 20040101
Lithostathine quadruple-helical filaments form proteinase K-resistant deposits in Creutzfeldt-Jakob disease. The Journal of biological chemistry 20031219
Temperature-dependent, irreversible formation of amyloid fibrils by a soluble human ataxin-3 carrying a moderately expanded polyglutamine stretch (Q36). Biochemistry 20031216
Cloning, expression, and assembly of sericin-like protein. The Journal of biological chemistry 20031114
Glycation induces formation of amyloid cross-beta structure in albumin. The Journal of biological chemistry 20031024
Biofilm formation at the air-liquid interface by the Pseudomonas fluorescens SBW25 wrinkly spreader requires an acetylated form of cellulose. Molecular microbiology 20031001
Spectroscopic investigation on gel-forming beta-sheet assemblage of peptide derivatives. Biopolymers 20031001
Suppression by polycyclic compounds of the conversion of human amylin into insoluble amyloid. The Biochemical journal 20030915
Synthesis and characterization of novel oxotechnetium (99Tc and 99mTc) and oxorhenium complexes from the 2,2'-bipyridine (NN)/thiol (S) mixed-ligand system. Inorganic chemistry 20030908
Expansion of polyglutamine induces the formation of quasi-aggregate in the early stage of protein fibrillization. The Journal of biological chemistry 20030905
A comparison of amyloid fibrillogenesis using the novel fluorescent compound K114. Journal of neurochemistry 20030901
Congo red analogues as potential anti-prion agents. Farmaco (Societa chimica italiana : 1989) 20030901
Longterm complete remission of AL-amyloid-related nephrotic syndrome. Clinical and experimental nephrology 20030901
Hydrogen exchange-mass spectrometry analysis of beta-amyloid peptide structure. Biochemistry 20030812
Assembly of the yeast prion Ure2p into protein fibrils. Thermodynamic and kinetic characterization. The Journal of biological chemistry 20030808
Effect of detergent on 'promiscuous' inhibitors. Journal of medicinal chemistry 20030731
A systematic investigation into the effect of protein destabilisation on beta 2-microglobulin amyloid formation. Journal of molecular biology 20030725
Amyloid protofilaments from the calcium-binding protein equine lysozyme: formation of ring and linear structures depends on pH and metal ion concentration. Journal of molecular biology 20030718
Local and long-range structural effects caused by the removal of the N-terminal polypeptide fragment from immunoglobulin L chain lambda. Biopolymers 20030601
Synthesis and evaluation of analogues of Congo red as potential compounds against transmissible spongiform encephalopathies. European journal of medicinal chemistry 20030601
Amphotericin B binds to amyloid fibrils and delays their formation: a therapeutic mechanism? Biochemistry 20030527
Amyloid-like fibril formation in an all beta-barrel protein. Partially structured intermediate state(s) is a precursor for fibril formation. The Journal of biological chemistry 20030516
Isolation of the MNN9 gene of Yarrowia lipolytica (YlMNN9) and phenotype analysis of a mutant ylmnn9 Delta strain. Yeast (Chichester, England) 20030501
Amyloid-enhancing factor mediates amyloid formation on fibroblasts via a nidus/template mechanism. Arthritis and rheumatism 20030501
Phenol Congo red staining enhances the diagnostic value of abdominal fat aspiration biopsy in reactive AA amyloidosis secondary to rheumatoid arthritis. Internal medicine (Tokyo, Japan) 20030501
Effects of Ocimum gratissimum L essential oil at subinhibitory concentrations on virulent and multidrug-resistant Shigella strains from Lagos, Nigeria. APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20030401
Reversible amyloid formation by the p53 tetramerization domain and a cancer-associated mutant. Journal of molecular biology 20030328
RHO1 (YlRHO1) is a non-essential gene in Yarrowia lipolytica and complements rho1Delta lethality in Saccharomyces cerevisiae. Yeast (Chichester, England) 20030301
Disaggregating effects of ethanol at low concentration on beta-poly-L-lysines. International journal of biological macromolecules 20030301
Aspirin and diabetes: inhibition of amylin aggregation by nonsteroidal anti-inflammatory drugs. Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 20030201
The native-like conformation of Ure2p in fibrils assembled under physiologically relevant conditions switches to an amyloid-like conformation upon heat-treatment of the fibrils. Journal of structural biology 20030201
Conformational restriction via cyclization in beta-amyloid peptide Abeta(1-28) leads to an inhibitor of Abeta(1-28) amyloidogenesis and cytotoxicity. Chemistry & biology 20030201
Pivotal role of oligomerization in expanded polyglutamine neurodegenerative disorders. Nature 20030123
Probing the role of backbone hydrogen bonding in beta-amyloid fibrils with inhibitor peptides containing ester bonds at alternate positions. Biochemistry 20030121
Pinacyanol as effective probe of fibrillar beta-amyloid peptide: comparative study with Congo Red. Biopolymers 20030101
In vitro evaluation of the anti-prionic activity of newly synthesized congo red derivatives. Arzneimittel-Forschung 20030101
Amyloid fibril formation by a synthetic peptide from a region of human acetylcholinesterase that is homologous to the Alzheimer's amyloid-beta peptide. Biochemistry 20021119
pH-responsive molecular nanocarriers based on dendritic core-shell architectures. Angewandte Chemie (International ed. in English) 20021115
Evidence for early cytotoxic aggregates in transgenic mice for human transthyretin Leu55Pro. The American journal of pathology 20021101
Ile-Lys-Val-Ala-Val (IKVAV)-containing laminin alpha1 chain peptides form amyloid-like fibrils. FEBS letters 20021023
Evaluation of different detection methods of biofilm formation in Staphylococcus aureus. Medical microbiology and immunology 20021001
Amyloid fibril formation by pentapeptide and tetrapeptide fragments of human calcitonin. The Journal of biological chemistry 20020920
DNA-induced partial unfolding of prion protein leads to its polymerisation to amyloid. Journal of molecular biology 20020906
Imaging Abeta plaques in living transgenic mice with multiphoton microscopy and methoxy-X04, a systemically administered Congo red derivative. Journal of neuropathology and experimental neurology 20020901
Discovery of natural products from Curcuma longa that protect cells from beta-amyloid insult: a drug discovery effort against Alzheimer's disease. Journal of natural products 20020901
A prionogenic peptide derived from Sup35 can force the whole GST fusion protein to show amyloid characteristics. Protein and peptide letters 20020801
Kinetics and energetics of assembly, nucleation, and growth of aggregates and fibrils for an amyloidogenic protein. Insights into transition states from pressure, temperature, and co-solute studies. The Journal of biological chemistry 20020726
Filipin prevents pathological prion protein accumulation by reducing endocytosis and inducing cellular PrP release. The Journal of biological chemistry 20020712
Regulation of yeast protein kinase C activity by interaction with the small GTPase Rho1p through its amino-terminal HR1 domain. Molecular microbiology 20020501
Purification, characterization, and modification of T lymphocyte-stimulating polysaccharide from spores of Ganoderma lucidum. Chemical & pharmaceutical bulletin 20020501
Long-term follow-up of systemic reactive AA amyloidosis secondary to rheumatoid arthritis: successful treatment with intermediate-dose corticosteroid. Internal medicine (Tokyo, Japan) 20020501
A common mechanism underlying promiscuous inhibitors from virtual and high-throughput screening. Journal of medicinal chemistry 20020411
Inhibition of transthyretin amyloid fibril formation by 2,4-dinitrophenol through tetramer stabilization. Archives of biochemistry and biophysics 20020401
Determination of sodium 3,4-diaminonaphthalene-1-sulfonate, a Congo Red derivative, in plasma and brain of hamsters by high-performance liquid chromatography after solid-phase extraction and ultraviolet absorbance. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020325
Macromolecular crowding accelerates amyloid formation by human apolipoprotein C-II. The Journal of biological chemistry 20020308
Familial Danish dementia: a novel form of cerebral amyloidosis associated with deposition of both amyloid-Dan and amyloid-beta. Journal of neuropathology and experimental neurology 20020301
Anaerobic reduction of a sulfonated azo dye, Congo Red, by sulfate-reducing bacteria. Applied biochemistry and biotechnology 20020301
Low levels of asparagine deamidation can have a dramatic effect on aggregation of amyloidogenic peptides: implications for the study of amyloid formation. Protein science : a publication of the Protein Society 20020201
Human stefin B readily forms amyloid fibrils in vitro. Biochimica et biophysica acta 20020131
Inhibitors of fibril formation and cytotoxicity of beta-amyloid peptide composed of KLVFF recognition element and flexible hydrophilic disrupting element. Biochemical and biophysical research communications 20020111
Neurodegeneration with tau accumulation in a transgenic mouse expressing V337M human tau. The Journal of neuroscience : the official journal of the Society for Neuroscience 20020101
A partially structured species of beta 2-microglobulin is significantly populated under physiological conditions and involved in fibrillogenesis. The Journal of biological chemistry 20011214
Solution conditions can promote formation of either amyloid protofilaments or mature fibrils from the HypF N-terminal domain. Protein science : a publication of the Protein Society 20011201
Inhibition of polyglutamine aggregation in R6/2 HD brain slices-complex dose-response profiles. Neurobiology of disease 20011201
Formation of filamentous tau aggregations in transgenic mice expressing V337M human tau. Neurobiology of disease 20011201
Enhanced anti-Shigella activity of erythromycin supplemented with sulfadiazine. FEMS immunology and medical microbiology 20011201
Shaping of colony elements in Laomedea flexuosa Hinks (Hydrozoa, Thecaphora) includes a temporal and spatial control of skeleton hardening. The Biological bulletin 20011201
Intra- and intermolecular beta-pleated sheet formation in glutamine-repeat inserted myoglobin as a model for polyglutamine diseases. The Journal of biological chemistry 20011130
Islet amyloid and type 2 diabetes: from molecular misfolding to islet pathophysiology. Biochimica et biophysica acta 20011129
Early formation of mature amyloid-beta protein deposits in a mutant APP transgenic model depends on levels of Abeta(1-42). Journal of neuroscience research 20011115
Chaperonin-mediated de novo generation of prion protein aggregates. Journal of molecular biology 20011102
Beta(2)-microglobulin and its deamidated variant, N17D form amyloid fibrils with a range of morphologies in vitro. Journal of molecular biology 20011026
Florid plaques in ovine PrP transgenic mice infected with an experimental ovine BSE. EMBO reports 20011015
A novel action of alzheimer's amyloid beta-protein (Abeta): oligomeric Abeta promotes lipid release. The Journal of neuroscience : the official journal of the Society for Neuroscience 20010915
Analysis of the minimal amyloid-forming fragment of the islet amyloid polypeptide. An experimental support for the key role of the phenylalanine residue in amyloid formation. The Journal of biological chemistry 20010907
Conformational intermediate of the amyloidogenic protein beta 2-microglobulin at neutral pH. The Journal of biological chemistry 20010831
Non-fibrillar oligomeric species of the amyloid ABri peptide, implicated in familial British dementia, are more potent at inducing apoptotic cell death than protofibrils or mature fibrils. Journal of molecular biology 20010629
Is Congo red an amyloid-specific dye? The Journal of biological chemistry 20010622
A new method for assessing foliar uptake of fungicides using Congo Red as a tracer. Pest management science 20010601
Self-assembly and gelation of oxidized glutathione in organic solvents. Journal of the American Chemical Society 20010516
Encystation of Acanthamoeba castellanii: dye uptake for assessment by flow cytometry and confocal laser scanning microscopy. Journal of applied microbiology 20010501
Pseudomonas aeruginosa protease IV enzyme assays and comparison to other Pseudomonas proteases. Analytical biochemistry 20010301
Phenotypic consequences of red-white colony type variation in Mycobacterium avium. Microbiology (Reading, England) 20010301
A cell-based method for the detection of nanomolar concentrations of bioactive amyloid. Analytical biochemistry 20010215
Regional distribution of amyloid-Bri deposition and its association with neurofibrillary degeneration in familial British dementia. The American journal of pathology 20010201
Age-dependent induction of congophilic neurofibrillary tau inclusions in tau transgenic mice. The American journal of pathology 20010201
Apolipoprotein A-I-derived amyloid in atherosclerosis. Its association with plasma levels of apolipoprotein A-I and cholesterol. American journal of clinical pathology 20010201
Spectroscopic evidence for amyloid-like interfacial self-assembly of hydrophobin Sc3. Biochemical and biophysical research communications 20010112
Genotypic and phenotypic characterization of potential virulence of intestinal avian Escherichia coli strains isolated in Algeria. Avian diseases 20010101
Selective inhibition of Abeta fibril formation. The Journal of biological chemistry 19960223
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