Serotonin 5-HT2C receptor-mediated inhibition of the M-current in hypothalamic POMC neurons.

American journal of physiology. Endocrinology and metabolism 20120601

Effects of serotonin 2C receptor agonists on the behavioral and neurochemical effects of cocaine in squirrel monkeys.

The Journal of pharmacology and experimental therapeutics 20120501

Methamphetamine, amphetamine, MDMA ('ecstasy'), MDA and mCPP modulate electrical and cholinergic input in PC12 cells.

Neurotoxicology 20120301

Influence of serotonergic 5-HT2C receptor antagonist mesulergine in the reversal of memory deficits induced by mCPP.

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP 20120201

Estradiol increases the anorexia associated with increased 5-HT(2C) receptor activation in ovariectomized rats.

Physiology & behavior 20120118

[Behavioral effects of ketanserine in prenatally stressed female rats].

Eksperimental'naia i klinicheskaia farmakologiia 20120101

Modulation of human GABAA receptor function: a novel mode of action of drugs of abuse.

Neurotoxicology 20111201

Safety, tolerability, and pharmacokinetics of once-daily trazodone extended-release caplets in healthy subjects.

International journal of clinical pharmacology and therapeutics 20111201

Differences in serotonin receptor expression in the brainstem may explain the differential ability of a serotonin agonist to block seizure-induced sudden death in DBA/2 vs. DBA/1 mice.

Brain research 20111018

Mirtazapine antagonises the subjective, hormonal and neuronal effects of m-chlorophenylpiperazine (mCPP) infusion: a pharmacological-challenge fMRI (phMRI) study.

NeuroImage 20110915

Control of hippocampal theta rhythm by serotonin: role of 5-HT2c receptors.

Neuropharmacology 20110901

Serotonin 2C receptor activates a distinct population of arcuate pro-opiomelanocortin neurons via TRPC channels.

Neuron 20110811

Hypophagic and hypolocomotive effects of metachloro phenyl piperazine in rats treated with theophylline and caffeine.

Pakistan journal of pharmaceutical sciences 20110701

The trazodone metabolite meta-chlorophenylpiperazine can cause false-positive urine amphetamine immunoassay results.

Journal of analytical toxicology 20110701

Pharmacologically induced alcohol craving in treatment seeking alcoholics correlates with alcoholism severity, but is insensitive to acamprosate.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20110501

The autonomic stress-induced hyperthermia response is not enhanced by several anxiogenic drugs.

Physiology & behavior 20110110

Separation of positional CPP isomers by chiral HPLC-DAD of seized tablets.

International journal of legal medicine 20110101

Altered 5-HT2C receptor agonist-induced responses and 5-HT2C receptor RNA editing in the amygdala of serotonin transporter knockout mice.

BMC pharmacology 20110101

[Effects of 5-HT1 and 5-HT2 serotonin receptors on anxiety- and depression-like behavior in female rats].

Eksperimental'naia i klinicheskaia farmakologiia 20110101

[Influence of 2-ethyl-6-methyl-3-hydroxypyridine hemisuccinate on cerebral blood perfusion in rats under experimental pathology conditions].

Eksperimental'naia i klinicheskaia farmakologiia 20110101

[Cerebrovascular and antiserotoninergic activity of the combination of tropoxin and mexidol].

Eksperimental'naia i klinicheskaia farmakologiia 20110101

Dose proportionality of once-daily trazodone extended-release caplets under fasting conditions.

Journal of clinical pharmacology 20101201

Blockade of 5-HT2A/2C-type receptors impairs learning in female rats in the course of estrous cycle.

Bulletin of experimental biology and medicine 20101201

Trazodone, meta-chlorophenylpiperazine (an hallucinogenic drug and trazodone metabolite), and the hallucinogen trifluoromethylphenylpiperazine cross-react with the EMIT®II ecstasy immunoassay in urine.

Journal of analytical toxicology 20101101

[Behavioral effects of m-CPP and ketanserine during ovarian cycle in female rats].

Eksperimental'naia i klinicheskaia farmakologiia 20101101

Hypothalamic orexin and pro-opiomelanocortin activities are essential for the anorexic effects of m-chlorophenylpiperazine in mice.

The international journal of neuropsychopharmacology 20101001

Multiple anxiogenic drugs recruit a parvalbumin-containing subpopulation of GABAergic interneurons in the basolateral amygdala.

Progress in neuro-psychopharmacology & biological psychiatry 20101001

5-HT2C receptor activation prevents stress-induced enhancement of brain 5-HT turnover and extracellular levels in the mouse brain: modulation by chronic paroxetine treatment.

Journal of neurochemistry 20101001

Detection of 1-benzylpiperazine, 1-(3-trifluoromethylphenyl)-piperazine, and 1-(3-chlorophenyl)-piperazine in 3,4-methylenedioxymethamphetamine-positive urine samples.

Journal of analytical toxicology 20101001

mCPP: an undesired addition to the ecstasy market.

Journal of psychopharmacology (Oxford, England) 20100901

[Effect of tropoxin on cerebrovascular effects of meta-chlorophenylpiperazine and serotonin].

Eksperimental'naia i klinicheskaia farmakologiia 20100901

Fear-potentiated startle, but not light-enhanced startle, is enhanced by anxiogenic drugs.

Pharmacology, biochemistry, and behavior 20100701

Tolerance to 3,4-methylenedioxymethamphetamine is associated with impaired serotonin release.

Addiction biology 20100701

Acute SSRI-induced anxiogenic and brain metabolic effects are attenuated 6 months after initial MDMA-induced depletion.

Behavioural brain research 20100305

The effects of the 5-HT2C agonist m-chlorophenylpiperazine on elite athletes with unexplained underperformance syndrome (overtraining).

British journal of sports medicine 20100301

Acquisition session length modulates consolidation effects produced by 5-HT2C ligands in a mouse autoshaping-operant procedure.

Behavioural pharmacology 20100301

Neuronal correlates and serotonergic modulation of behavioural inhibition and reward in healthy and antisocial individuals.

Journal of psychiatric research 20100201

5-hydroxytryptamine receptor stimulation of mitochondrial biogenesis.

The Journal of pharmacology and experimental therapeutics 20100201

Role of spinal serotonergic pathways in sneeze-induced urethral continence reflex in rats.

American journal of physiology. Renal physiology 20091001

Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Nature chemical biology 20091001

Characterizing the effects of 5-HT(2C) receptor ligands on motor activity and feeding behaviour in 5-HT(2C) receptor knockout mice.

Neuropharmacology 20090901

Serotonin 5-HT2C receptor-independent expression of hypothalamic NOR1, a novel modulator of food intake and energy balance, in mice.

Biochemical and biophysical research communications 20090821

Individual differences in the sensitivity to serotonergic drugs: a pharmacobehavioural approach using rats selected on the basis of their response to novelty.

Psychopharmacology 20090801

Fluvoxamine exerts anorexic effect in 5-HT2C receptor mutant mice with heterozygous mutation of beta-endorphin gene.

The international journal of neuropsychopharmacology 20090501

Selective serotonin reuptake inhibitors modify physiological gastrointestinal motor activities via 5-HT2c receptor and acyl ghrelin.

Biological psychiatry 20090501

1-(m-Chlorophenyl)piperazine induces depressogenic-like behaviour in rodents by stimulating the neuronal 5-HT(2A) receptors: proposal of a modified rodent antidepressant assay.

European journal of pharmacology 20090417

Synergistic actions of apomorphine and m-chlorophenylpiperazine on ejaculation, but not penile erection in rats.

Biomedical research (Tokyo, Japan) 20090401

Behavioral and neurochemical profile of m-CPP following exposure to single restraint stress in rat.

Acta neurologica Belgica 20090301

Subthalamic neurons show increased firing to 5-HT2C receptor activation in 6-hydroxydopamine-lesioned rats.

Brain research 20090223

Creation and application of psychoactive designer drugs data library using liquid chromatography with photodiode array spectrophotometry detector and gas chromatography-mass spectrometry.

Talanta 20090215

Prevalence of ergot derivatives in natural ryegrass pastures: detection and pathogenicity in the horse.

Theriogenology 20090201

Distribution and neurochemical characterization of neurons within the nucleus of the solitary tract responsive to serotonin agonist-induced hypophagia.

Behavioural brain research 20090103

Trazodone generates m-CPP: in 2008 risks from m-CPP might outweigh benefits of trazodone.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 20090101

Anti-inflammatory effects of m-chlorophenylpiperazine in brain glia cells.

International immunopharmacology 20081210

Dopaminergic and serotonergic modulation of persistent behaviour in the reinforced spatial alternation model of obsessive-compulsive disorder.

Psychopharmacology 20081101

Relationship of the serotonin transporter with prolactin response to meta-chlorophenylpiperazine in cocaine dependence.

Journal of psychiatric research 20081001

Effects of chemotherapeutic agents 5-fluorouracil and methotrexate alone and combined in a mouse model of learning and memory.

Psychopharmacology 20080901

Hypersensitivity of 5-HT2 receptors in OCD patients. An increased prolactin response after a challenge with meta-chlorophenylpiperazine and pre-treatment with ritanserin and placebo.

Journal of psychiatric research 20080901

Taste-dependent sociophobia: when food and company do not mix.

Behavioural brain research 20080822

HPLC analysis of the antidepressant trazodone and its main metabolite m-CPP in human plasma.

Journal of pharmaceutical and biomedical analysis 20080805

High throughput and sensitive determination of trazodone and its primary metabolite, m-chlorophenylpiperazine, in human plasma by liquid chromatography-tandem mass spectrometry.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20080801

Exercise is associated with reduction in the anxiogenic effect of mCPP on acoustic startle.

Behavioral neuroscience 20080801

5-HT(2C) receptor activation is a common mechanism on proerectile effects of apomorphine, oxytocin and melanotan-II in rats.

European journal of pharmacology 20080728

Serotonin systems upregulate the expression of hypothalamic NUCB2 via 5-HT2C receptors and induce anorexia via a leptin-independent pathway in mice.

Biochemical and biophysical research communications 20080718

Behavioral effects of 1-(m-chlorophenyl)piperazine (m-CPP) in a rat model of tardive dyskinesia.

Pakistan journal of pharmaceutical sciences 20080701

Antagonism of AMPA receptors produces anxiolytic-like behavior in rodents: effects of GYKI 52466 and its novel analogues.

Psychopharmacology 20080601

Rikkunshito, an herbal medicine, suppresses cisplatin-induced anorexia in rats via 5-HT2 receptor antagonism.

Gastroenterology 20080601

Acute chlorophenylpiperazine overdose: a case report and review of the literature.

Therapeutic drug monitoring 20080601

Detection of novel reactive metabolites of trazodone: evidence for CYP2D6-mediated bioactivation of m-chlorophenylpiperazine.

Drug metabolism and disposition: the biological fate of chemicals 20080501

Effects of a Cannabinoid1 receptor antagonist and Serotonin2C receptor agonist alone and in combination on motivation for palatable food: a dose-addition analysis study in mice.

The Journal of pharmacology and experimental therapeutics 20080501

Behavioral characterization of serotonergic activation in the flatworm Planaria.

Behavioural pharmacology 20080501

m-CPP induced hypolocomotion does not interfere in the assessment of memory functions in rats.

Pakistan journal of pharmaceutical sciences 20080401

Stereotypic behaviour in the deer mouse: pharmacological validation and relevance for obsessive compulsive disorder.

Progress in neuro-psychopharmacology & biological psychiatry 20080215

5-HT2 receptor activation in the midbrain periaqueductal grey (PAG) reduces anxiety-like behaviour in mice.

Behavioural brain research 20080211

Ejaculatory response induced by a 5-HT2 receptor agonist m-CPP in rats: differential roles of 5-HT2 receptor subtypes.

Pharmacology, biochemistry, and behavior 20080201

Serotonin 2C receptor agonists improve type 2 diabetes via melanocortin-4 receptor signaling pathways.

Cell metabolism 20071107

MDMA-like behavioral effects of N-substituted piperazines in the mouse.

Pharmacology, biochemistry, and behavior 20071101

Fluvoxamine, a selective serotonin reuptake inhibitor, and 5-HT2C receptor inactivation induce appetite-suppressing effects in mice via 5-HT1B receptors.

The international journal of neuropsychopharmacology 20071001

Behavioural effects of rapid intravenous administration of meta-chlorophenylpiperazine (m-CPP) in patients with generalized social anxiety disorder, panic disorder and healthy controls.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20071001

Adrenergic and serotoninergic regulation of myocardial contractility in patients with various morphofunctional changes in the heart resulting from chronic heart failure.

Bulletin of experimental biology and medicine 20071001

Proof of a 1-(3-chlorophenyl)piperazine (mCPP) intake: use as adulterant of cocaine resulting in drug-drug interactions?

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070815

Trazodone inhibits T-type calcium channels.

Neuropharmacology 20070801

Possible involvement of spinal noradrenergic mechanisms in the antiallodynic effect of intrathecally administered 5-HT2C receptor agonists in the rats with peripheral nerve injury.

European journal of pharmacology 20070712

Amygdala-prefrontal disconnection in borderline personality disorder.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20070701

Neurochemical and behavioral effects of m-CPP in a rat model of tardive dyskinesia.

Pakistan journal of pharmaceutical sciences 20070701

5-HT2 modulation of AY-9944 induced atypical absence seizures.

Neuroscience letters 20070511

High-throughput quantitation of nefazodone and its metabolites in human plasma by high flow direct-injection LC-MS/MS.

Journal of pharmaceutical and biomedical analysis 20070411

Anxiogenic-like effects of mCPP microinfusions into the amygdala (but not dorsal or ventral hippocampus) in mice exposed to elevated plus-maze.

Behavioural brain research 20070312

5-Hydroxytryptamine2C receptor contribution to m-chlorophenylpiperazine and N-methyl-beta-carboline-3-carboxamide-induced anxiety-like behavior and limbic brain activation.

The Journal of pharmacology and experimental therapeutics 20070301

Effect of meta-chlorophenylpiperazine and cholecystokinin on food intake of Osborne-Mendel and S5B/P1 rats.

Obesity (Silver Spring, Md.) 20070301

Influence of diltiazem on the behavior of zolpidem-treated mice in the elevated-plus maze test.

Journal of neural transmission (Vienna, Austria : 1996) 20070201

Amphetamine and mCPP effects on dopamine and serotonin striatal in vivo microdialysates in an animal model of hyperactivity.

Neurotoxicity research 20070201

Anxiolytic activity of a novel potent serotonin 5-HT2C receptor antagonist FR260010: a comparison with diazepam and buspirone.

European journal of pharmacology 20061228

Hyperphagia alters expression of hypothalamic 5-HT2C and 5-HT1B receptor genes and plasma des-acyl ghrelin levels in Ay mice.

Endocrinology 20061201

Serotonin dysfunction in pathological gamblers: increased prolactin response to oral m-CPP versus placebo.

CNS spectrums 20061201

Polymorphism in the serotonin transporter gene and moderators of prolactin response to meta-chlorophenylpiperazine in African-American cocaine abusers and controls.

Psychiatry research 20061115

[Role of the serotonergic nervous system in anxiety disorders and the anxiolytic mechanism of selective serotonin reuptake inhibitors].

Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology 20061101

Role of the 5-HT2C receptor in improving weight-supported stepping in adult rats spinalized as neonates.

Brain research 20060927

Relationship of prolactin response to meta-chlorophenylpiperazine with severity of drug use in cocaine dependence.

Human psychopharmacology 20060801

Functional magnetic resonance imaging and c-Fos mapping in rats following an anorectic dose of m-chlorophenylpiperazine.

NeuroImage 20060701

Effects of soybean food pellets on m-CPP-induced anxiety model of mice.

Biological & pharmaceutical bulletin 20060701

Pharmacological evaluation of the stress-induced social avoidance model of anxiety.

Brain research bulletin 20060331

Childhood sexual abuse in relation to neurobiological challenge tests in patients with borderline personality disorder and normal controls.

Psychiatry research 20060330

A negative feedback system between brain serotonin systems and plasma active ghrelin levels in mice.

Biochemical and biophysical research communications 20060317

Relationship of disinhibition and aggression to blunted prolactin response to meta-chlorophenylpiperazine in cocaine-dependent patients.

Psychopharmacology 20060301

Serotonin 1B and 2C receptor interactions in the modulation of feeding behaviour in the mouse.

Psychopharmacology 20060301

5-HT2c receptor activation induces grooming behaviour in rats: possible correlations with obsessive-compulsive disorder.

Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology 20060301

Does meta-chlorophenylpiperazine (mCPP) activate human platelets?

Platelets 20060201

gamma-Aminobutyric acid-serotonin interactions in healthy men: implications for network models of psychosis and dissociation.

Biological psychiatry 20060115

Medial parabrachial nucleus neurons modulate d-fenfluramine-induced anorexia through 5HT2C receptors.

Brain research 20060105

Discriminative stimulus effects of 3,4-methylenedioxymethamphetamine (MDMA) in humans trained to discriminate among d-amphetamine, meta-chlorophenylpiperazine and placebo.

Drug and alcohol dependence 20060104

Effects of mu-CPP and mesulergine on dietary choices in deprived rats: possible mechanisms of their action.

Progress in neuro-psychopharmacology & biological psychiatry 20060101

[Metachlorophenylpiperazine (mCPP): a new designer drug].

Therapie 20060101

Development of a solid phase extraction for 13 'new' generation antidepressants and their active metabolites for gas chromatographic-mass spectrometric analysis.

Journal of chromatography. A 20051209

Estradiol supplementation modulates neuroendocrine response to M-chlorophenylpiperazine in menstrual status migrainosus triggered by oral contraception-free interval.

Human reproduction (Oxford, England) 20051201

Selective and nonselective serotonin antagonists block the aversive stimulus properties of MK212 and m-chlorophenylpiperazine (mCPP) in mice.

Neuropharmacology 20051201

Methylone and mCPP, two new drugs of abuse?

Addiction biology 20051201

Ethanol substitutes for the discriminative stimulus effects of m-chlorophenylpiperazine.

Brain research 20051116

m-Chlorophenylpiperazine exacerbates perception of salicylate-induced tinnitus in rats.

The European journal of neuroscience 20051101

Effect of 5-hydroxytryptamine on neurogenic vasoconstriction in the isolated, autoperfused hindquarters of the rat.

Clinical and experimental pharmacology & physiology 20051001

Association of the promoter polymorphism -1438G/A of the 5-HT2A receptor gene with behavioral impulsiveness and serotonin function in women with bulimia nervosa.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 20050805

Serotonergic/glutamatergic interactions: potentiation of phencyclidine-induced stimulus control by citalopram.

Pharmacology, biochemistry, and behavior 20050701

Brain angiotensin and anxiety-related behavior: the transgenic rat TGR(ASrAOGEN)680.

Brain research 20050607

The use of sudden darkness in mice: a behavioural and pharmacological approach.

Psychopharmacology 20050601

Effects of 5,7-dihydroxytryptamine lesion of the dorsal raphe nucleus on ethanol discrimination in the rat.

Alcohol (Fayetteville, N.Y.) 20050601

Reinforced spatial alternation as an animal model of obsessive-compulsive disorder (OCD): investigation of 5-HT2C and 5-HT1D receptor involvement in OCD pathophysiology.

Biological psychiatry 20050515

Trazodone and its active metabolite m-chlorophenylpiperazine as partial agonists at 5-HT1A receptors assessed by [35S]GTPgammaS binding.

Journal of psychopharmacology (Oxford, England) 20050501

Effects of serotonin and serotonergic agonists and antagonists on the production of tumor necrosis factor alpha and interleukin-6.

Psychiatry research 20050430

Effect of the activation of central 5-HT2C receptors by the 5-HT2C agonist mCPP on blood pressure and heart rate in rats.

Brain research 20050408

Measurement and characterization of energy intake in the mouse.

Current protocols in pharmacology 20050401

Agonist diversity in 5-HT(2C) receptor-mediated weight control in rats.

Psychopharmacology 20050301

m-CPP, a 5-HT2C receptor agonist that modifies the perfusion pressure of the hindquarter vascular bed of anesthetized rat.

Pharmacology 20050201

Serotonergic systems associated with arousal and vigilance behaviors following administration of anxiogenic drugs.

Neuroscience 20050101

Anxiety-like state associates with taste to produce conditioned taste aversion.

Biological psychiatry 20041201

Neuroimaging and 5-HT2C receptor polymorphism: a HMPAO-SPECT study in healthy male probands using mCPP-challenge of the 5-HT2C receptor.

Pharmacopsychiatry 20041101

Reduced hypophagic effects of d-fenfluramine and the 5-HT2C receptor agonist mCPP in 5-HT1B receptor knockout mice.

Psychopharmacology 20041001

Behavioural effects of rapid intravenous administration of meta-chlorophenylpiperazine in patients with panic disorder and controls.

European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 20041001

Increased repetitive behaviours and prolactin responsivity to oral m-chlorophenylpiperazine in adults with autism spectrum disorders.

The international journal of neuropsychopharmacology 20040901

Differential effects of 5-HT1 and 5-HT2 receptor agonists on hindlimb movements in paraplegic mice.

Progress in neuro-psychopharmacology & biological psychiatry 20040901

A 5-HT2C agonist elicits hyperactivity and oral dyskinesia with hypophagia in rabbits.

Physiology & behavior 20040801

Chronic treatment with fluvoxamine desensitizes 5-HT2C receptor-mediated hypolocomotion in rats.

Pharmacology, biochemistry, and behavior 20040801

Pharmacokinetics of m-chlorophenylpiperazine after intravenous and oral administration in healthy male volunteers: implication for the pharmacodynamic profile.

Pharmacopsychiatry 20040701

Vasoconstrictor responses to 5-hydroxytryptamine in the autoperfused hindquarters of spontaneously hypertensive rats.

Pharmacology 20040601

Serotonin function, personality-trait variations, and childhood abuse in women with bulimia-spectrum eating disorders.

The Journal of clinical psychiatry 20040601

mCPP-induced hyperactivity in 5-HT2C receptor mutant mice is mediated by activation of multiple 5-HT receptor subtypes.

Neuropharmacology 20040401

The application of the principles of clinical drug development to pharmacological challenge tests of the serotonergic system.

Journal of psychopharmacology (Oxford, England) 20040301

m-Chlorophenylpiperazine (mCPP) modulates the discriminative stimulus effects of cocaine through actions at the 5-HT2C receptor.

Behavioral neuroscience 20040201

Neurobiological correlates of diagnosis and underlying traits in patients with borderline personality disorder compared with normal controls.

Psychiatry research 20040101

Modification of human 5-HT(2C) receptor function by Cys23Ser, an abundant, naturally occurring amino-acid substitution.

Molecular psychiatry 20040101

Bulimia nervosa with co-morbid avoidant personality disorder: behavioural characteristics and serotonergic function.

Psychological medicine 20040101

Serotonergic dissection of obsessive compulsive symptoms: a challenge study with m-chlorophenylpiperazine and sumatriptan.

Neuropsychobiology 20040101

5-HT2C receptors inhibit and 5-HT1A receptors activate the generation of spike-wave discharges in a genetic rat model of absence epilepsy.

Experimental neurology 20031201

Implications of compulsive and impulsive traits for serotonin status in women with bulimia nervosa.

Psychiatry research 20031015

A PET study after treatment with an anxiety-provoking agent, m-chlorophenyl-piperazine, in conscious rhesus monkeys.

Journal of nuclear medicine : official publication, Society of Nuclear Medicine 20030901

Central 5-HT2B/2C and 5-HT3 receptor stimulation decreases salt intake in sodium-depleted rats.

Brain research 20030815

Discriminative stimulus effects of m-chlorophenylpiperazine as a model of the role of serotonin receptors in anxiety.

Life sciences 20030801

Serotonin in the dorsal periaqueductal gray modulates inhibitory avoidance and one-way escape behaviors in the elevated T-maze.

European journal of pharmacology 20030725

Neuroendocrine response to the serotonin agonist M-chlorophenylpiperazine in women with menstrual status migrainosus.

Neuroendocrinology 20030701

m-CPP-induced self-grooming is mediated by 5-HT2C receptors.

Behavioural brain research 20030616

Effects of single and repeated electroconvulsive shock on the social and agonistic behaviour of resident rats.

Neuropharmacology 20030601

Oral administration of the 5-HT2Creceptor agonist, mCPP, reduces body weight gain in rats over 28 days as a result of maintained hypophagia.

Psychopharmacology 20030501

Experimental anxiety and antiepileptics: the effects of valproate and vigabatrin in the mirrored chamber test.

Methods and findings in experimental and clinical pharmacology 20030501

Effects of m-CPP in altering neuronal function: blocking depolarization in invertebrate motor and sensory neurons but exciting rat dorsal horn neurons.

Brain research 20030418

Neurogenic dural protein extravasation induced by meta-chlorophenylpiperazine (mCPP) involves nitric oxide and 5-HT2B receptor activation.

Cephalalgia : an international journal of headache 20030301

Reduced social interaction following 3,4-methylenedioxymethamphetamine is not associated with enhanced 5-HT 2C receptor responsivity.

Neuropharmacology 20030301

Induction of c-Fos expression in specific areas of the fear circuitry in rat forebrain by anxiogenic drugs.

Biological psychiatry 20030215

Effect of repeated administration of dexfenfluramine on feeding and brain Fos in mice.

Physiology & behavior 20030201

Central serotonergic effects of m-chlorophenylpiperazine (mCPP) among normal control adolescents.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20030101

5-HT1B receptor knockout mice show a compensatory reduction in 5-HT2C receptor function.

The European journal of neuroscience 20030101

Piperazine-derived designer drug 1-(3-chlorophenyl)piperazine (mCPP): GC-MS studies on its metabolism and its toxicological detection in rat urine including analytical differentiation from its precursor drugs trazodone and nefazodone.

Journal of analytical toxicology 20030101

Anxiolytic-like profile of propofol, a general anesthetic, in the plus-maze test in mice.

Polish journal of pharmacology 20030101

Neuroendocrine response to meta-chlorophenylpiperazine and ipsapirone in relation to anxiety and aggression.

Psychiatry research 20021215

Sleep-wake effects of meta-chlorophenyl piperazine and mianserin in the behaviorally depressed rat.

European journal of pharmacology 20021122

2'-NH(2)-MPTP [1-methyl-4-(2'-aminophenyl)-1,2,3,6-tetrahydropyridine] depletes serotonin and norepinephrine in rats: a comparison with 2'-CH(3)-MPTP [1-methyl-4-(2'-methylphenyl)-1,2,3,6-tetrahydropyridine].

The Journal of pharmacology and experimental therapeutics 20021101

5-HT2C receptor mediation of unconditioned escape behaviour in the unstable elevated exposed plus maze.

Psychopharmacology 20021101

The effects of gender and gonadal steroids on the neuroendocrine and temperature response to m-chlorophenylpiperazine in leuprolide-induced hypogonadism in women and men.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20021101

Allelic variants of the serotonin(2C) receptor and neuroendocrinological responses to the serotonin(2C) receptor agonist m-chlorophenylpiperazine in healthy male volunteers.

Pharmacopsychiatry 20021101

Effects of GABA(A) compounds on mCPP drug discrimination in rats.

Life sciences 20021018

mCPP-induced hypophagia in rats is unaffected by the profile of dietary unsaturated fatty acids.

Pharmacology, biochemistry, and behavior 20021001

p-Methylthioamphetamine and 1-(m-chlorophenyl)piperazine, two non-neurotoxic 5-HT releasers in vivo, differ from neurotoxic amphetamine derivatives in their mode of action at 5-HT nerve endings in vitro.

Journal of neurochemistry 20020901

5-HT(2C) receptor activation by m-chlorophenylpiperazine detected in humans with fMRI.

Neuroreport 20020827

Relationship between plasma concentrations of trazodone and its active metabolite, m-chlorophenylpiperazine, and its clinical effect in depressed patients.

Therapeutic drug monitoring 20020801

Metachlorophenylpiperazine (m-CPP) induced intracavernous pressure responses in anaesthetized rats.

International journal of impotence research 20020801

The effects of serotonin agonists on the hypothalamic regulation of sexual receptivity in Syrian hamsters.

Hormones and behavior 20020801

Central administration of mCPP, a serotonin 5-HT(2B/2C) agonist, decreases water intake in rats.

Pharmacology, biochemistry, and behavior 20020701

Blunted prefrontal cortical 18fluorodeoxyglucose positron emission tomography response to meta-chlorophenylpiperazine in impulsive aggression.

Archives of general psychiatry 20020701

Ritanserin antagonism of m-chlorophenylpiperazine effects in neuroleptic-free schizophrenics patients: support for serotonin-2 receptor modulation of schizophrenia symptoms.

Psychopharmacology 20020601

Ethopharmacological analysis of the unstable elevated exposed plus maze, a novel model of extreme anxiety: predictive validity and sensitivity to anxiogenic agents.

Psychopharmacology 20020501

Altered prolactin response to M-chlorophenylpiperazine in monkeys previously treated with 3,4-methylenedioxymethamphetamine (MDMA) or fenfluramine.

Synapse (New York, N.Y.) 20020401

Serotonin 2C receptor agonists and the behavioural satiety sequence in mice.

Pharmacology, biochemistry, and behavior 20020401

Alteration in 5-hydroxytryptamine agonist-induced behaviour following a corticosterone implant in adult rats.

Pharmacology, biochemistry, and behavior 20020401

Role of 5-hT2C receptors in the hypophagic effect of m-CPP, ORG 37684 and CP-94,253 in the rat.

Progress in neuro-psychopharmacology & biological psychiatry 20020401

Comparison of the potency of MDL 100,907 and SB 242084 in blocking the serotonin (5-HT)(2) receptor agonist-induced increases in rat serum corticosterone concentrations: evidence for 5-HT(2A) receptor mediation of the HPA axis.

Neuropharmacology 20020201

Effects of fenfluramine, m-CPP and triazolam on repeated-acquisition in squirrel monkeys before and after neurotoxic MDMA administration.

Psychopharmacology 20020201

Perturbations of plasma cortisol and DHEA-S following discontinuation of cocaine use in cocaine addicts.

Psychoneuroendocrinology 20020101

The subjective effects of MDMA and mCPP in moderate MDMA users.

Drug and alcohol dependence 20011201

The effect of olanzapine treatment on m-chlorophenylpiperazine-induced hormone release in schizophrenia.

Journal of clinical psychopharmacology 20011201

The 5-HT2C/2B receptor agonist m-chlorophenylpiperazine (mCPP) inhibits 2-deoxy-D-glucose (2-DG)-induced hyperphagia in rats.

Biological & pharmaceutical bulletin 20011201

Anxiety-like effects induced by acute fluoxetine, sertraline or m-CPP treatment are reversed by pretreatment with the 5-HT2C receptor antagonist SB-242084 but not the 5-HT1A receptor antagonist WAY-100635.

The international journal of neuropsychopharmacology 20011201

m-CPP hypolocomotion is selectively antagonized by compounds with high affinity for 5-HT(2C) receptors but not 5-HT(2A) or 5-HT(2B) receptors.

Behavioural pharmacology 20011201

Altered responsiveness to 5-HT at the crayfish neuromuscular junction due to chronic p-CPA and m-CPP treatment.

Brain research 20011019

Association of serotonin and cortisol indices with childhood abuse in bulimia nervosa.

Archives of general psychiatry 20010901

Mapping of brain activation in response to pharmacological agents using fMRI in the rat.

Magnetic resonance imaging 20010901

Agonist-induced functional desensitization of recombinant human 5-HT2 receptors expressed in CHO-K1 cells.

Biochemical pharmacology 20010815

Self-destructiveness and serotonin function in bulimia nervosa.

Psychiatry research 20010805

Pedophilia is accompanied by increased plasma concentrations of catecholamines, in particular epinephrine.

Psychiatry research 20010805

Tryptophan hydroxylase gene and major psychoses.

Psychiatry research 20010805

Altered response to meta-chlorophenylpiperazine in anorexia nervosa: support for a persistent alteration of serotonin activity after short-term weight restoration.

The International journal of eating disorders 20010701

Effect of a low tryptophan diet on the prolactin responses to the 5-HT2A agonist DOI in the rat.

Pharmacopsychiatry 20010701

The serotonergic 5-HT(2C) agonist m-chlorophenylpiperazine increases weight-supported locomotion without development of tolerance in rats with spinal transections.

Experimental neurology 20010601

A neurotoxic dose of 3,4-methylenedioxymethamphetamine (MDMA; ecstasy) to rats results in a long-term defect in thermoregulation.

Psychopharmacology 20010601

1-(m-chlorophenyl)piperazine (mCPP) dissociates in vivo serotonin release from long-term serotonin depletion in rat brain.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010501

Dissociation of systemic and hippocampal modulation of rat locomotor activity by 5-HT(2C) receptors.

Neuroscience research 20010501

Decreased tryptophan availability but normal post-synaptic 5-HT2c receptor sensitivity in chronic fatigue syndrome.

Psychological medicine 20010501

Effects of genetic polymorphism of CYP1A2 inducibility on the steady-state plasma concentrations of trazodone and its active metabolite m-chlorophenylpiperazine in depressed Japanese patients.

Pharmacology & toxicology 20010501

Effect of aerobic exercise on behavioral and neuroendocrine responses to meta-chlorophenylpiperazine and to ipsapirone in untrained healthy subjects.

Psychopharmacology 20010501

Neuroendocrine and behavioral responses to mCPP in Obsessive-Compulsive Disorder.

Psychoneuroendocrinology 20010201

Increased m-CPP-induced oral dyskinesia after lesion of serotonergic neurons.

Pharmacology, biochemistry, and behavior 20010201

Investigations into migraine pathogenesis: time course for effects of m-CPP, BW723C86 or glyceryl trinitrate on appearance of Fos-like immunoreactivity in rat trigeminal nucleus caudalis (TNC).

Cephalalgia : an international journal of headache 20010201

Low versus standard dose mCPP challenge in obsessive-compulsive patients.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010101

Lower baseline plasma cortisol and prolactin together with increased body temperature and higher mCPP-induced cortisol responses in men with pedophilia.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20010101

Implications of impulsive and affective symptoms for serotonin function in bulimia nervosa.

Psychological medicine 20010101

Evidence that orexin-A-evoked grooming in the rat is mediated by orexin-1 (OX1) receptors, with downstream 5-HT2C receptor involvement.

Psychopharmacology 20010101

m-Chlorophenylpiperazine excites non-dopaminergic neurons in the rat substantia nigra and ventral tegmental area by activating serotonin-2C receptors.

Neuroscience 20010101

Cloning, expression, and characterization of ferret 5-HT(3) receptor subunit.

European journal of pharmacology 20000707

Serotonin(2C) receptors appear to mediate genetic sensitivity to cocaine-induced convulsions.

Psychopharmacology 19991001

Nefazodone, meta-chlorophenylpiperazine, and their metabolites in vitro: cytochromes mediating transformation, and P450-3A4 inhibitory actions.

Psychopharmacology 19990701

Trazodone is metabolized to m-chlorophenylpiperazine by CYP3A4 from human sources.

Drug metabolism and disposition: the biological fate of chemicals 19980601

Effect of fenfluramine challenge on cocaine craving in addicted male users.

The American journal on addictions 19980101

The putative 5-HT1A receptor antagonist DU125530 blocks the discriminative stimulus of the 5-HT1A receptor agonist flesinoxan in pigeons.

European journal of pharmacology 19970501

SB 242084, a selective and brain penetrant 5-HT2C receptor antagonist.

Neuropharmacology 19970101

In vitro and in vivo profile of SB 206553, a potent 5-HT2C/5-HT2B receptor antagonist with anxiolytic-like properties.

British journal of pharmacology 19960201

Post-synaptic 5-HT1A receptor involvement in yawning and penile erections induced by apomorphine, physostigmine and mCPP in rats.

Psychopharmacology 19950801

Trazodone treatment increases plasma prolactin concentrations in depressed patients.

International clinical psychopharmacology 19950601

Penile erection and yawning induced by 5-HT1C receptor agonists in male rats: relationship with dopaminergic and oxytocinergic transmission.

European journal of pharmacology 19940811

Prolonged penile erections induced by hydroxyzine: possible mechanism of action.

Neuropsychobiology 19940101

d-Fenfluramine- and d-norfenfluramine-induced hypophagia: differential mechanisms and involvement of postsynaptic 5-HT receptors.

European journal of pharmacology 19930921

Trazodone induction of migraine headache through mCPP.

The American journal of psychiatry 19920501

A pilot placebo-controlled study of chronic m-CPP administration in Alzheimer's disease.

Biological psychiatry 19910715

Serotonergic responsivity in obsessive-compulsive disorder. Effects of chronic clomipramine treatment.

Archives of general psychiatry 19880201

1-m-Chlorophenylpiperazine is an active metabolite common to the psychotropic drugs trazodone, etoperidone and mepiprazole.

The Journal of pharmacy and pharmacology 19821001