2-Amino-4-(butylsulfonimidoyl)butanoic acid
| Title | Journal |
|---|---|
| Establishment of a drug-induced rhabdomyolysis mouse model by co-administration of ciprofloxacin and atorvastatin. | Toxicology letters 20180701 |
| Neutrophil depletion protects against zomepirac-induced acute kidney injury in mice. | Chemico-biological interactions 20180105 |
| Establishment of a novel mouse model for pioglitazone-induced skeletal muscle injury. | Toxicology 20170501 |
| Nanotoxicity of cobalt induced by oxidant generation and glutathione depletion in MCF-7 cells. | Toxicology in vitro : an international journal published in association with BIBRA 20170401 |
| The dental monomer hydroxyethyl methacrylate (HEMA) counteracts lipopolysaccharide-induced IL-1β release-Possible role of glutathione. | Toxicology letters 20170315 |
| High-content imaging-based BAC-GFP toxicity pathway reporters to assess chemical adversity liabilities. | Archives of toxicology 20170101 |
| Osteoblasts activate the Nrf2 signalling pathway in response to arsenic trioxide treatment. | The international journal of biochemistry & cell biology 20161001 |
| MicroRNA-mediated Th2 bias in methimazole-induced acute liver injury in mice. | Toxicology and applied pharmacology 20160915 |
| Inhibition of Macrophage CD36 Expression and Cellular Oxidized Low Density Lipoprotein (oxLDL) Accumulation by Tamoxifen: A PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR (PPAR)γ-DEPENDENT MECHANISM. | The Journal of biological chemistry 20160812 |
| Chromatin remodeling by curcumin alters endogenous aryl hydrocarbon receptor signaling. | Chemico-biological interactions 20160525 |
| The role of GSH in microcystin-induced apoptosis in rat liver: Involvement of oxidative stress and NF-κB. | Environmental toxicology 20160501 |
| Kupffer cell-mediated exacerbation of methimazole-induced acute liver injury in rats. | Journal of applied toxicology : JAT 20160501 |
| Metabolic activation of furan moiety makes Diosbulbin B hepatotoxic. | Archives of toxicology 20160401 |
| Different ATM Signaling in Response to Chromium(VI) Metabolism via Ascorbate and Nonascorbate Reduction: Implications for in Vitro Models and Toxicogenomics. | Environmental health perspectives 20160101 |
| Alternatively Spliced Methionine Synthase in SH-SY5Y Neuroblastoma Cells: Cobalamin and GSH Dependence and Inhibitory Effects of Neurotoxic Metals and Thimerosal. | Oxidative medicine and cellular longevity 20160101 |
| NADPH Oxidase-Dependent Mechanism Explains How Arsenic and Other Oxidants Can Activate Aryl Hydrocarbon Receptor Signaling. | Chemical research in toxicology 20151221 |
| The role of glutathione detoxification pathway in MCLR-induced hepatotoxicity in SD rats. | Environmental toxicology 20151201 |
| Cytotoxicity of luteolin in primary rat hepatocytes: the role of CYP3A-mediated ortho-benzoquinone metabolite formation and glutathione depletion. | Journal of applied toxicology : JAT 20151101 |
| Glutathione Depletion Accelerates Cigarette Smoke-Induced Inflammation and Airspace Enlargement. | Toxicological sciences : an official journal of the Society of Toxicology 20151001 |
| Inhibition of Glutathione Production Induces Macrophage CD36 Expression and Enhances Cellular-oxidized Low Density Lipoprotein (oxLDL) Uptake. | The Journal of biological chemistry 20150904 |
| Genotoxic effect of ethacrynic acid and impact of antioxidants. | Toxicology and applied pharmacology 20150701 |
| Reactive Sulfur Species-Mediated Activation of the Keap1-Nrf2 Pathway by 1,2-Naphthoquinone through Sulfenic Acids Formation under Oxidative Stress. | Chemical research in toxicology 20150518 |
| Auranofin induces apoptosis and necrosis in HeLa cells via oxidative stress and glutathione depletion. | Molecular medicine reports 20150201 |
| Isoliquiritigenin attenuates oxidative hepatic damage induced by carbon tetrachloride with or without buthionine sulfoximine. | Chemico-biological interactions 20150105 |
| Demethylation of neferine in human liver microsomes and formation of quinone methide metabolites mediated by CYP3A4 accentuates its cytotoxicity. | Chemico-biological interactions 20141205 |
| Retinoic acid synergizes ATO-mediated cytotoxicity by precluding Nrf2 activity in AML cells. | British journal of cancer 20140826 |
| Metabolic pathways leading to detoxification of triptolide, a major active component of the herbal medicine Tripterygium wilfordii. | Journal of applied toxicology : JAT 20140801 |
| Manganese superoxide dismutase knock-down in 3T3-L1 preadipocytes impairs subsequent adipogenesis. | Molecular and cellular biochemistry 20140801 |
| Arsenic trioxide induced indirect and direct inhibition of glutathione reductase leads to apoptosis in rat hepatocytes. | Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine 20140601 |
| Sec-containing TrxR1 is essential for self-sufficiency of cells by control of glucose-derived H2O2. | Cell death & disease 20140501 |
| Cadmium selectively induces MIP-2 and COX-2 through PTEN-mediated Akt activation in RAW264.7 cells. | Toxicological sciences : an official journal of the Society of Toxicology 20140401 |
| Stress-induced stimulation of choline transport in cultured choroid plexus epithelium exposed to low concentrations of cadmium. | American journal of physiology. Regulatory, integrative and comparative physiology 20140301 |
| Involvement of the Nrf2 pathway in the regulation of pterostilbene-induced apoptosis in HeLa cells via ER stress. | Journal of pharmacological sciences 20140101 |
| In vivo roles of conjugation with glutathione and O6-alkylguanine DNA-alkyltransferase in the mutagenicity of the bis-electrophiles 1,2-dibromoethane and 1,2,3,4-diepoxybutane in mice. | Chemical research in toxicology 20131118 |
| A novel mouse model for phenytoin-induced liver injury: involvement of immune-related factors and P450-mediated metabolism. | Toxicological sciences : an official journal of the Society of Toxicology 20131101 |
| Role of drug-independent stress factors in liver injury associated with diclofenac intake. | Toxicology 20131004 |
| Inhibition of glutathione biosynthesis alters compartmental redox status and the thiol proteome in organogenesis-stage rat conceptuses. | Free radical biology & medicine 20131001 |
| Nerve growth factor exhibits an antioxidant and an autocrine activity in mouse liver that is modulated by buthionine sulfoximine, arsenic, and acetaminophen. | Free radical research 20130501 |
| Cellular glutathione plays a key role in copper uptake mediated by human copper transporter 1. | American journal of physiology. Cell physiology 20130415 |
| Sodium arsenite induces cyclooxygenase-2 expression in human uroepithelial cells through MAPK pathway activation and reactive oxygen species induction. | Toxicology in vitro : an international journal published in association with BIBRA 20130401 |
| Identification of novel liver-specific mRNAs in plasma for biomarkers of drug-induced liver injury and quantitative evaluation in rats treated with various hepatotoxic compounds. | Toxicological sciences : an official journal of the Society of Toxicology 20130301 |
| Neurotoxicity of 'ecstasy' and its metabolites in human dopaminergic differentiated SH-SY5Y cells. | Toxicology letters 20130204 |
| Copper ions stimulate the proliferation of hepatic stellate cells via oxygen stress in vitro. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20130201 |
| Protection by chrysin, apigenin, and luteolin against oxidative stress is mediated by the Nrf2-dependent up-regulation of heme oxygenase 1 and glutamate cysteine ligase in rat primary hepatocytes. | Archives of toxicology 20130101 |
| A metal mixture induces transformation upon antioxidant depletion in a hepatic cell line. | Annals of hepatology 20130101 |
| Effect of glutathione depletion on Nrf2/ARE activation by deltamethrin in PC12 Cells. | Arhiv za higijenu rada i toksikologiju 20130101 |
| Microcystin-LR induced reactive oxygen species mediate cytoskeletal disruption and apoptosis of hepatocytes in Cyprinus carpio L. | PloS one 20130101 |
| Glutathione and glutaredoxin act as a backup of human thioredoxin reductase 1 to reduce thioredoxin 1 preventing cell death by aurothioglucose. | The Journal of biological chemistry 20121102 |
| Molecular modulated cysteine-selective fluorescent probe. | Biomaterials 20121101 |
| Cadmium-induced apoptosis in the BJAB human B cell line: involvement of PKC/ERK1/2/JNK signaling pathways in HO-1 expression. | Toxicology 20121028 |
| Chimeric mice with a humanized liver as an animal model of troglitazone-induced liver injury. | Toxicology letters 20121002 |
| Th2 cytokine-mediated methimazole-induced acute liver injury in mice. | Journal of applied toxicology : JAT 20121001 |
| Buthionine sulfoximine and 1,25-dihydroxyvitamin D induce apoptosis in breast cancer cells via induction of reactive oxygen species. | Cancer investigation 20121001 |
| miR395 is a general component of the sulfate assimilation regulatory network in Arabidopsis. | FEBS letters 20120921 |
| Carnosic acid prevents 6-hydroxydopamine-induced cell death in SH-SY5Y cells via mediation of glutathione synthesis. | Chemical research in toxicology 20120917 |
| Low-dose methylmercury-induced oxidative stress, cytotoxicity, and tau-hyperphosphorylation in human neuroblastoma (SH-SY5Y) cells. | Environmental toxicology 20120901 |
| Calcineurin expression and activity is regulated by the intracellular redox status and under hypertension in human neutrophils. | The Journal of endocrinology 20120901 |
| Comparative evaluation of small-molecule chemosensitizers in reversal of cisplatin resistance in ovarian cancer cells. | Anticancer research 20120901 |
| Immunoregulatory effects of glutathione during mesenchymal stem cell differentiation to hepatocyte-like cells. | Iranian journal of immunology : IJI 20120901 |
| MMPT as a reactive oxygen species generator induces apoptosis via the depletion of intracellular GSH contents in A549 cells. | European journal of pharmacology 20120805 |
| Pro-oxidant induced DNA damage in human lymphoblastoid cells: homeostatic mechanisms of genotoxic tolerance. | Toxicological sciences : an official journal of the Society of Toxicology 20120801 |
| Involvement of reactive oxygen species and glutathione in gallic acid-induced human umbilical vein endothelial cell death. | Oncology reports 20120801 |
| Arsenic trioxide induces human pulmonary fibroblast cell death via increasing ROS levels and GSH depletion. | Oncology reports 20120801 |
| Redox state alters anti-cancer effects of wedelolactone. | Environmental and molecular mutagenesis 20120801 |
| Repair of oxidative DNA damage is delayed in the Ser326Cys polymorphic variant of the base excision repair protein OGG1. | Mutagenesis 20120701 |
| New insights into redox response modulation in Fanconi's anemia cells by hydrogen peroxide and glutathione depletors. | The FEBS journal 20120701 |
| CYP3A-mediated apoptosis of dauricine in cultured human bronchial epithelial cells and in lungs of CD-1 mice. | Toxicology and applied pharmacology 20120615 |
| Cardiovascular and renal manifestations of glutathione depletion induced by buthionine sulfoximine. | American journal of hypertension 20120601 |
| Sustained intrahepatic glutathione depletion causes proteasomal degradation of multidrug resistance-associated protein 2 in rat liver. | Biochimica et biophysica acta 20120601 |
| Phytochelatins play a key role in arsenic accumulation and tolerance in the aquatic macrophyte Wolffia globosa. | Environmental pollution (Barking, Essex : 1987) 20120601 |
| TRPM2 channel protective properties of N-acetylcysteine on cytosolic glutathione depletion dependent oxidative stress and Ca2+ influx in rat dorsal root ganglion. | Physiology & behavior 20120515 |
| Essential role of intracellular glutathione in controlling ascorbic acid transporter expression and function in rat hepatocytes and hepatoma cells. | Free radical biology & medicine 20120501 |
| Influence of glutathione chemical effectors in the response of maize to arsenic exposure. | Journal of plant physiology 20120501 |
| Quercetin enhancement of arsenic-induced apoptosis via stimulating ROS-dependent p53 protein ubiquitination in human HaCaT keratinocytes. | Experimental dermatology 20120501 |
| Reactive oxygen species regulate the replication of porcine circovirus type 2 via NF-κB pathway. | Virology 20120425 |
| Modulation of liver L-γ-glutamyl-L-cysteinylglycine homeostasis by N-acetyl-glucosamine-thiazolidine-4(R)-carboxylic acid in mice. | The American journal of the medical sciences 20120401 |
| Aluminum-induced oxidative stress and changes in antioxidant defenses in the roots of rice varieties differing in Al tolerance. | Plant cell reports 20120401 |
| Fission yeast HMT1 lowers seed cadmium through phytochelatin-dependent vacuolar sequestration in Arabidopsis. | Plant physiology 20120401 |
| Glutathione is required by Rhizobium etli for glutamine utilization and symbiotic effectiveness. | Molecular plant-microbe interactions : MPMI 20120301 |
| ZINC TOLERANCE INDUCED BY IRON 1 reveals the importance of glutathione in the cross-homeostasis between zinc and iron in Arabidopsis thaliana. | The Plant journal : for cell and molecular biology 20120301 |
| Endosulfan upregulates AP-1 binding and ARE-mediated transcription via ERK1/2 and p38 activation in HepG2 cells. | Toxicology 20120206 |
| Inhibition of glutathione synthesis reverses Krüppel-like factor 4-mediated cisplatin resistance. | Cancer chemotherapy and pharmacology 20120201 |
| Copper-induced synthesis of ascorbate, glutathione and phytochelatins in the marine alga Ulva compressa (Chlorophyta). | Plant physiology and biochemistry : PPB 20120201 |
| Oxidative stress causes mineralocorticoid receptor activation in rat cardiomyocytes: role of small GTPase Rac1. | Hypertension (Dallas, Tex. : 1979) 20120201 |
| Transport and cytotoxicity of the anticancer drug 3-bromopyruvate in the yeast Saccharomyces cerevisiae. | Journal of bioenergetics and biomembranes 20120201 |
| Intracellular GSH and ascorbate inhibit radical-induced protein chain peroxidation in HL-60 cells. | Free radical biology & medicine 20120115 |
| Simultaneous inhibition of glutathione- and thioredoxin-dependent metabolism is necessary to potentiate 17AAG-induced cancer cell killing via oxidative stress. | Free radical biology & medicine 20120115 |
| Resistance of neuroblastoma GI-ME-N cell line to glutathione depletion involves Nrf2 and heme oxygenase-1. | Free radical biology & medicine 20120115 |
| Inhibition of cyclooxygenase-2 and inducible nitric oxide synthase by silymarin in proliferating mesenchymal stem cells: comparison with glutathione modifiers. | Journal of natural medicines 20120101 |
| Oxidant-mediated modification of the cellular thiols is sufficient for arginase activation in cultured cells. | Molecular and cellular biochemistry 20120101 |
| Genomic instability induced by mutant succinate dehydrogenase subunit D (SDHD) is mediated by O2(-•) and H2O2. | Free radical biology & medicine 20120101 |
| Drought and salt stress tolerance of an Arabidopsis glutathione S-transferase U17 knockout mutant are attributed to the combined effect of glutathione and abscisic acid. | Plant physiology 20120101 |
| Dissecting the role of glutathione biosynthesis in Plasmodium falciparum. | Molecular microbiology 20120101 |
| Estrogen prevents oxidative damage to the mitochondria in Friedreich's ataxia skin fibroblasts. | PloS one 20120101 |
| Implications of altered glutathione metabolism in aspirin-induced oxidative stress and mitochondrial dysfunction in HepG2 cells. | PloS one 20120101 |
| Isoliquiritigenin treatment induces apoptosis by increasing intracellular ROS levels in HeLa cells. | Journal of Asian natural products research 20120101 |
| Multidrug resistance associated protein 1 together with glutathione plays a protective role against 4-hydroxy-2-nonenal-induced oxidative stress in bovine aortic endothelial cells. | Biological & pharmaceutical bulletin 20120101 |
| Human adipose tissue-derived multilineage progenitor cells exposed to oxidative stress induce neurite outgrowth in PC12 cells through p38 MAPK signaling. | BMC cell biology 20120101 |
| Implication of glutathione in the in vitro antiplasmodial mechanism of action of ellagic acid. | PloS one 20120101 |
| Susceptibility of human head and neck cancer cells to combined inhibition of glutathione and thioredoxin metabolism. | PloS one 20120101 |
| Inhibition of mitochondrial respiration and rapid depletion of mitochondrial glutathione by β-phenethyl isothiocyanate: mechanisms for anti-leukemia activity. | Antioxidants & redox signaling 20111215 |
| Cellular adaptive response to glutathione depletion modulates endothelial dysfunction triggered by TNF-α. | Toxicology letters 20111215 |
| Monomethylarsenic diglutathione transport by the human multidrug resistance protein 1 (MRP1/ABCC1). | Drug metabolism and disposition: the biological fate of chemicals 20111201 |
| Taurine suppresses oxidative stress-potentiated expression of lectin-like oxidized low-density lipoprotein receptor and restenosis in balloon-injured rabbit iliac artery. | Clinical and experimental pharmacology & physiology 20111201 |
| Subcellular distribution of glutathione precursors in Arabidopsis thaliana. | Journal of integrative plant biology 20111201 |
| Effects of inorganic and organic arsenic compounds on growth and apoptosis of human T-lymphoblastoid leukemia cells. | Anticancer research 20111201 |
| GSH-mediated S-transarylation of a quinone glyceraldehyde-3-phosphate dehydrogenase conjugate. | Chemical research in toxicology 20111121 |
| Protective effect of components isolated from Lindera erythrocarpa against oxidative stress-induced apoptosis of H9c2 cardiomyocytes. | Phytotherapy research : PTR 20111101 |
| The cystine/cysteine cycle and GSH are independent and crucial antioxidant systems in malignant melanoma cells and represent druggable targets. | Antioxidants & redox signaling 20111101 |
| Fluoride-induced genotoxicity in mouse bone marrow cells: effect of buthionine sulfoximine and N-acetyl-L-cysteine. | Journal of applied toxicology : JAT 20111001 |
| Regulation of the system x(C)- cystine/glutamate exchanger by intracellular glutathione levels in rat astrocyte primary cultures. | Glia 20111001 |
| The balance between 4-hydroxynonenal and intrinsic glutathione/glutathione S-transferase A4 system may be critical for the epidermal growth factor receptor phosphorylation of human esophageal squamous cell carcinomas. | Molecular carcinogenesis 20111001 |
| Enhancement of carboplatin-mediated lung cancer cell killing by simultaneous disruption of glutathione and thioredoxin metabolism. | Clinical cancer research : an official journal of the American Association for Cancer Research 20111001 |
| Accurate performance of a rat model of schizophrenia in the water maze depends on visual cue availability and stability: a distortion in cognitive mapping abilities? | Behavioural brain research 20110930 |
| Promising effects of the 4HPR-BSO combination in neuroblastoma monolayers and spheroids. | Free radical biology & medicine 20110915 |
| Preclinical evaluation of azathioprine plus buthionine sulfoximine in the treatment of human hepatocarcinoma and colon carcinoma. | World journal of gastroenterology 20110914 |
| Sex difference in susceptibility to acetaminophen hepatotoxicity is reversed by buthionine sulfoximine. | Toxicology 20110905 |
| The key enzyme of sulfate assimilation, adenosine 5'-phosphosulfate reductase, is regulated by HY5 in Arabidopsis. | The Plant journal : for cell and molecular biology 20110901 |
| Effects of glutathione-depleting drug buthionine sulfoximine and aging on activity of endothelium-derived relaxing and contracting factors in carotid artery of Sprague-Dawley rats. | Journal of cardiovascular pharmacology 20110901 |
| The role of the glutathione system in seizures induced by diphenyl diselenide in rat pups. | Chemico-biological interactions 20110815 |
| Potential contribution of oxidative stress and inflammation to anxiety and hypertension. | Brain research 20110802 |
| Critical roles of cellular glutathione homeostasis and jnk activation in andrographolide-mediated apoptotic cell death in human hepatoma cells. | Molecular carcinogenesis 20110801 |
| Vacuolar H+ -ATPase c protects glial cell death induced by sodium nitroprusside under glutathione-depleted condition. | Journal of cellular biochemistry 20110801 |
| Modulation of intracellular glutathione affects adipogenesis in 3T3-L1 cells. | Journal of cellular physiology 20110801 |
| Oxidative state and IL-6 production in intestinal myofibroblasts of Crohn's disease patients. | Inflammatory bowel diseases 20110801 |
| Glutathione modulates Ca(2+) influx and oxidative toxicity through TRPM2 channel in rat dorsal root ganglion neurons. | The Journal of membrane biology 20110801 |
| In vivo prevention of bladder urotoxicity: purified hydroxytyrosol ameliorates urotoxic effects of cyclophosphamide and buthionine sulfoximine in mice. | International journal of toxicology 20110801 |
| Osteonecrosis development in a novel rat model characterized by a single application of oxidative stress. | Arthritis and rheumatism 20110701 |
| Selective toxicity of glycyrrhetinic acid against tumorigenic r/m HM-SFME-1 cells is potentially attributed to downregulation of glutathione. | Biochimie 20110701 |
| Estrogen protection in Friedreich's ataxia skin fibroblasts. | Endocrinology 20110701 |
| Insulin-like growth factor 1 and transforming growth factor-β stimulate cystine/glutamate exchange activity in dental pulp cells. | Journal of endodontics 20110701 |
| The cap'n'collar transcription factor Nrf2 mediates both intrinsic resistance to environmental stressors and an adaptive response elicited by chemopreventive agents that determines susceptibility to electrophilic xenobiotics. | Chemico-biological interactions 20110630 |
| Glutathione is a physiologic reservoir of neuronal glutamate. | Biochemical and biophysical research communications 20110617 |
| Redox-responsive polyphosphate nanosized assemblies: a smart drug delivery platform for cancer therapy. | Biomacromolecules 20110613 |
| Differential augmentative effects of buthionine sulfoximine and ascorbic acid in As2O3-induced ovarian cancer cell death: oxidative stress-independent and -dependent cytotoxic potentiation. | International journal of oncology 20110601 |
| In vivo and in vitro assessment of the role of glutathione antioxidant system in anthracycline-induced cardiotoxicity. | Archives of toxicology 20110501 |
| Ticlopidine-induced hepatotoxicity in a GSH-depleted rat model. | Archives of toxicology 20110401 |
| Depletion of glutathione does not affect electron transport chain complex activity in brain mitochondria: Implications for Parkinson disease and postmortem studies. | Free radical biology & medicine 20110401 |
| Characterization of an Arabidopsis cadmium-resistant mutant cdr3-1D reveals a link between heavy metal resistance as well as seed development and flowering. | Planta 20110401 |
| Intracellular glutathione levels are involved in carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone-induced apoptosis in As4.1 juxtaglomerular cells. | International journal of molecular medicine 20110401 |
| Nitric oxide is the primary mediator of cytotoxicity induced by GSH depletion in neuronal cells. | Journal of cell science 20110401 |
| Redox-regulatory mechanisms induced by oxidative stress in Brassica juncea roots monitored by 2-DE proteomics. | Proteomics 20110401 |
| In vivo inhibition of l-buthionine-(S,R)-sulfoximine-induced cataracts by a novel antioxidant, N-acetylcysteine amide. | Free radical biology & medicine 20110315 |
| Oxidative stress in relation to telomere length maintenance in vascular smooth muscle cells following balloon angioplasty. | Journal of physiology and biochemistry 20110301 |
| Imaging in real-time with FRET the redox response of tumorigenic cells to glutathione perturbations in a microscale flow. | Integrative biology : quantitative biosciences from nano to macro 20110301 |
| Oxidative stress causes renal angiotensin II type 1 receptor upregulation, Na+/H+ exchanger 3 overstimulation, and hypertension. | Hypertension (Dallas, Tex. : 1979) 20110301 |
| Antimicrobial peptides increase tolerance to oxidant stress in Drosophila melanogaster. | The Journal of biological chemistry 20110225 |
| Sortin1-hypersensitive mutants link vacuolar-trafficking defects and flavonoid metabolism in Arabidopsis vegetative tissues. | Chemistry & biology 20110225 |
| Cellular glutathione content modulates the effect of andrographolide on β-naphthoflavone-induced CYP1A1 mRNA expression in mouse hepatocytes. | Toxicology 20110204 |
| The gender-dependent difference of liver GSH antioxidant system in mice and its influence on isoline-induced liver injury. | Toxicology 20110204 |
| The inhibitory effect of raloxifene on lipopolysaccharide-induced nitric oxide production in RAW264.7 cells is mediated through a ROS/p38 MAPK/CREB pathway to the up-regulation of heme oxygenase-1 independent of estrogen receptor. | Biochimie 20110201 |
| The nitric oxide prodrug JS-K is effective against non-small-cell lung cancer cells in vitro and in vivo: involvement of reactive oxygen species. | The Journal of pharmacology and experimental therapeutics 20110201 |
| Efficacy of glutathione in ameliorating sulfur mustard analog-induced toxicity in cultured skin epidermal cells and in SKH-1 mouse skin in vivo. | The Journal of pharmacology and experimental therapeutics 20110201 |
| Effect of protein S-glutathionylation on Ca2+ homeostasis in cultured aortic endothelial cells. | American journal of physiology. Heart and circulatory physiology 20110201 |
| Cellular iron depletion weakens induction of heme oxygenase-1 by cadmium. | The international journal of biochemistry & cell biology 20110101 |
| Transient alteration of cellular redox buffering before irradiation triggers apoptosis in head and neck carcinoma stem and non-stem cells. | PloS one 20110101 |
| PKCδ sensitizes neuroblastoma cells to L-buthionine-sulfoximine and etoposide inducing reactive oxygen species overproduction and DNA damage. | PloS one 20110101 |
| Ascorbic acid prevents oxidant-induced increases in endothelial permeability. | BioFactors (Oxford, England) 20110101 |
| (-)Schisandrin B ameliorates paraquat-induced oxidative stress by suppressing glutathione depletion and enhancing glutathione recovery in differentiated PC12 cells. | BioFactors (Oxford, England) 20110101 |
| Progression of ventricular remodeling and arrhythmia in the primary hyperoxidative state of glutathione-depleted rats. | Circulation journal : official journal of the Japanese Circulation Society 20110101 |
| A redox microenvironment is essential for MAPK-dependent secretion of pro-inflammatory cytokines: modulation by glutathione (GSH/GSSG) biosynthesis and equilibrium in the alveolar epithelium. | Cellular immunology 20110101 |
| Regulation of hypoxia inducible factor-1α expression by the alteration of redox status in HepG2 cells. | Journal of experimental & clinical cancer research : CR 20110101 |
| Toxicity induced by cumene hydroperoxide in PC12 cells: protective role of thiol donors. | Journal of biochemical and molecular toxicology 20110101 |
| Involvement of oxidative stress in simvastatin-induced apoptosis of murine CT26 colon carcinoma cells. | Toxicology letters 20101215 |
| The role of intracellular glutathione in the progression of Chlamydia trachomatis infection. | Free radical biology & medicine 20101215 |
| In vitro cytotoxicity assay to evaluate the toxicity of an electrophilic reactive metabolite using glutathione-depleted rat primary cultured hepatocytes. | Chemico-biological interactions 20101205 |
| Cytotoxicity of dentine bonding agents on human pulp cells is related to intracellular glutathione levels. | International endodontic journal 20101201 |
| Protective effect of sulforaphane against cisplatin-induced mitochondrial alterations and impairment in the activity of NAD(P)H: quinone oxidoreductase 1 and γ glutamyl cysteine ligase: studies in mitochondria isolated from rat kidney and in LLC-PK1 cells. | Toxicology letters 20101110 |
| Identification of a pentatricopeptide repeat protein implicated in splicing of intron 1 of mitochondrial nad7 transcripts. | The Journal of biological chemistry 20101015 |
| Nanotoxicity of pure silica mediated through oxidant generation rather than glutathione depletion in human lung epithelial cells. | Toxicology 20101009 |
| Reactive oxygen species and glutathione level changes by a proteasome inhibitor, MG132, partially affect calf pulmonary arterial endothelial cell death. | Drug and chemical toxicology 20101001 |
| Tissue-specific effects of fenthion on glutathione metabolism modulated by NAC and BSO in Oreochromis niloticus. | Drug and chemical toxicology 20101001 |
| Arabidopsis root growth dependence on glutathione is linked to auxin transport. | Plant cell reports 20101001 |
| Mechanism-based biomarker gene sets for glutathione depletion-related hepatotoxicity in rats. | Toxicology and applied pharmacology 20100915 |
| The redox state of the glutathione/glutathione disulfide couple mediates intracellular arginase activation in HCT-116 colon cancer cells. | Digestive diseases and sciences 20100901 |
| Exposure of rice seedlings to heat shock protects against subsequent Cd-induced decrease in glutamine synthetase activity and increase in specific protease activity in leaves. | Journal of plant physiology 20100901 |
| VEGF antagonists decrease barrier function of retinal pigment epithelium in vitro: possible participation of intracellular glutathione. | Investigative ophthalmology & visual science 20100901 |
| Effect of BSO-supplemented heavy metals on antioxidant enzymes in Arabidopsis thaliana. | Ecotoxicology and environmental safety 20100901 |
| Proline improves copper tolerance in chickpea (Cicer arietinum). | Protoplasma 20100901 |
| Astrocytes retain their antioxidant capacity into advanced old age. | Glia 20100901 |
| Evidence for the role of oxidative stress in the acetylation of histone H3 by ethanol in rat hepatocytes. | Alcohol (Fayetteville, N.Y.) 20100901 |
| Glutathione modulation and oxidative stress in human liver slices. | Current drug discovery technologies 20100901 |
| Role of glutaredoxin1 and glutathione in regulating the activity of the copper-transporting P-type ATPases, ATP7A and ATP7B. | The Journal of biological chemistry 20100827 |
| Combined ascorbate and glutathione deficiency leads to decreased cytochrome b5 expression and impaired reduction of sulfamethoxazole hydroxylamine. | Archives of toxicology 20100801 |
| Gallic acid-induced lung cancer cell death is related to glutathione depletion as well as reactive oxygen species increase. | Toxicology in vitro : an international journal published in association with BIBRA 20100801 |
| Effect of glutathione depletion on removal of copper from LEC rat livers by tetrathiomolybdate. | Journal of inorganic biochemistry 20100801 |
| Role of sympathetic tone in BSO-induced hypertension in mice. | American journal of hypertension 20100801 |
| Enhanced glutathione efflux from astrocytes in culture by low extracellular Ca2+ and curcumin. | Neurochemical research 20100801 |
| Chronic oxidative stress and sympathetic vasomotor tone in arterial hypertension. | American journal of hypertension 20100801 |
| Effect of glutathione redox state on Leydig cell susceptibility to acute oxidative stress. | Molecular and cellular endocrinology 20100729 |
| System x(c)- and thioredoxin reductase 1 cooperatively rescue glutathione deficiency. | The Journal of biological chemistry 20100716 |
| Inhibitory effects of glutathione on dengue virus production. | Biochemical and biophysical research communications 20100702 |
| Arsenic trioxide and ascorbic acid demonstrate promising activity against primary human CLL cells in vitro. | Leukemia research 20100701 |
| The glutaredoxin/glutathione system modulates NF-kappaB activity by glutathionylation of p65 in cinnamaldehyde-treated endothelial cells. | Toxicological sciences : an official journal of the Society of Toxicology 20100701 |
| Oxidative stress and information content of black and yellow plumage coloration: an experiment with greenfinches. | The Journal of experimental biology 20100701 |
| Methionine restriction up-regulates the expression of the pi class of glutathione S-transferase partially via the extracellular signal-regulated kinase-activator protein-1 signaling pathway initiated by glutathione depletion. | Molecular nutrition & food research 20100601 |
| Glutathione synthesis inhibitor butathione sulfoximine regulates ceruloplasmin by dual but opposite mechanism: Implication in hepatic iron overload. | Free radical biology & medicine 20100601 |
| The effects of antimycin A on endothelial cells in cell death, reactive oxygen species and GSH levels. | Toxicology in vitro : an international journal published in association with BIBRA 20100601 |
| Spinal levels of nonprotein thiols are related to nociception in mice. | The journal of pain : official journal of the American Pain Society 20100601 |
| Genetic analysis of cytoprotective functions supported by graded expression of Keap1. | Molecular and cellular biology 20100601 |
| Cytoprotective effect of (-)-deprenyl, (-)desmethyl-deprenyl and (-)deprenyl-N-oxide on glutathione depleted A-2058 melanoma cells. | Journal of neural transmission (Vienna, Austria : 1996) 20100601 |
| Acetaminophen-induced cytotoxicity on human normal liver L-02 cells and the protection of antioxidants. | Toxicology mechanisms and methods 20100601 |
| Arsenite induces oxidative injury in rat brain: synergistic effect of iron. | Annals of the New York Academy of Sciences 20100601 |
| Dual mechanisms of NF-kappaB inhibition in carnosol-treated endothelial cells. | Toxicology and applied pharmacology 20100515 |
| Oxidized low-density lipoprotein increases osteopontin expression by generation of oxidative stress. | Free radical biology & medicine 20100515 |
| Structural basis for feedback and pharmacological inhibition of Saccharomyces cerevisiae glutamate cysteine ligase. | The Journal of biological chemistry 20100507 |
| Cytotoxicity of chlorhexidine on human osteoblastic cells is related to intracellular glutathione levels. | International endodontic journal 20100501 |
| Rat brain endothelial cells are a target of manganese toxicity. | Brain research 20100422 |
| Paclitaxel combined with inhibitors of glucose and hydroperoxide metabolism enhances breast cancer cell killing via H2O2-mediated oxidative stress. | Free radical biology & medicine 20100415 |
| Moderate treadmill exercise prevents oxidative stress-induced anxiety-like behavior in rats. | Behavioural brain research 20100402 |
| The effects of N-acetyl cysteine on the MG132 proteasome inhibitor-treated lung cancer cells in relation to cell growth, reactive oxygen species and glutathione. | International journal of molecular medicine 20100401 |
| Glutathione modulators reverse the pro-tumour effect of growth factors enhancing WiDr cell response to chemotherapeutic agents. | Anticancer research 20100401 |
| The changes of reactive oxygen species and glutathione by MG132, a proteasome inhibitor affect As4.1 juxtaglomerular cell growth and death. | Chemico-biological interactions 20100330 |
| Influence of toluene co-exposure on the metabolism and genotoxicity of benzene in mice using continuous and intermittent exposures. | Chemico-biological interactions 20100319 |
| Silencing glycogen synthase kinase-3beta inhibits acetaminophen hepatotoxicity and attenuates JNK activation and loss of glutamate cysteine ligase and myeloid cell leukemia sequence 1. | The Journal of biological chemistry 20100312 |
| Differential expression of TRPM2 and TRPV4 channels and their potential role in oxidative stress-induced cell death in organotypic hippocampal culture. | Neurotoxicology 20100301 |
| Glutathione S-transferase M1 inhibits dexamethasone-induced apoptosis in association with the suppression of Bim through dual mechanisms in a lymphoblastic leukemia cell line. | Cancer science 20100301 |
| Neurotoxicity screening in a multipotent neural stem cell line established from the mouse brain. | Journal of Korean medical science 20100301 |
| Reducible poly(amido ethylenimine)-based gene delivery system for improved nucleus trafficking of plasmid DNA. | Bioconjugate chemistry 20100217 |
| Effect of antioxidants during bovine in vitro fertilization procedures on spermatozoa and embryo development. | Reproduction in domestic animals = Zuchthygiene 20100201 |
| Effects of glutathione depletion and age on skeletal muscle performance and morphology following chronic stretch-shortening contraction exposure. | European journal of applied physiology 20100201 |
| Effects of age and glutathione levels on oxidative stress in rats after chronic exposure to stretch-shortening contractions. | European journal of applied physiology 20100201 |
| Chronic oxidative stress causes increased tau phosphorylation in M17 neuroblastoma cells. | Neuroscience letters 20100114 |
| Effect of N-acetylcysteine on sympathetic hyperinnervation in post-infarcted rat hearts. | Cardiovascular research 20100101 |
| Naturally- and experimentally-designed restorations of the Parkin gene deficit in autosomal recessive juvenile parkinsonism. | Biochemical and biophysical research communications 20100101 |
| In vivo imaging of free radicals and oxygen. | Methods in molecular biology (Clifton, N.J.) 20100101 |
| In vitro and in vivo activation of astrocytes by amyloid-beta is potentiated by pro-oxidant agents. | Journal of Alzheimer's disease : JAD 20100101 |
| Developmental potential of bovine oocytes following IVM in the presence of glutathione ethyl ester. | Reproduction, fertility, and development 20100101 |
| Buthionine sulfoximine promotes methylglyoxal-induced apoptotic cell death and oxidative stress in endothelial cells. | Biological & pharmaceutical bulletin 20100101 |
| Sensitization effect of thimerosal is mediated in vitro via reactive oxygen species and calcium signaling. | Toxicology 20100101 |
| Glutathione deficiency down-regulates hepatic lipogenesis in rats. | Lipids in health and disease 20100101 |
| Exogenous coenzyme Q10 modulates MMP-2 activity in MCF-7 cell line as a breast cancer cellular model. | Nutrition journal 20100101 |
| Oxidized low density lipoprotein decreases Rankl-induced differentiation of osteoclasts by inhibition of Rankl signaling. | Journal of cellular physiology 20091201 |
| Redox-related antimelanoma activity of ATN-224. | Melanoma research 20091201 |
| Antimony-trioxide- and arsenic-trioxide-induced apoptosis in myelogenic and lymphatic cell lines, recruitment of caspases, and loss of mitochondrial membrane potential are enhanced by modulators of the cellular glutathione redox system. | Annals of hematology 20091101 |
| Generation of oxidant response to copper and iron nanoparticles and salts: Stimulation by ascorbate. | Chemico-biological interactions 20091030 |
| Manganese inhibits the ability of astrocytes to promote neuronal differentiation. | Toxicology and applied pharmacology 20091015 |
| Cadmium-induced apoptotic death of human retinal pigment epithelial cells is mediated by MAPK pathway. | Experimental eye research 20091001 |
| Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. | Nature chemical biology 20091001 |
| Glutathione modulation reverses the growth-promoting effect of growth factors, improving the 5-fluorouracil antitumour response in WiDr colon cancer cells. | Anticancer research 20091001 |
| Lack of nucleophilic addition in the isoxazole and pyrazole diketone modified analogs of curcumin; implications for their antitumor and chemosensitizing activities. | Chemico-biological interactions 20090914 |
| The role of intracellular glutathione in inorganic mercury-induced toxicity in neuroblastoma cells. | Neurochemical research 20090901 |
| Suppression of acrylamide toxicity by carboxyfullerene in human neuroblastoma cells in vitro. | Archives of toxicology 20090901 |
| Characterization of the cancer chemopreventive NRF2-dependent gene battery in human keratinocytes: demonstration that the KEAP1-NRF2 pathway, and not the BACH1-NRF2 pathway, controls cytoprotection against electrophiles as well as redox-cycling compounds. | Carcinogenesis 20090901 |
| Effects of glutathione depletion on hypoxia-induced erythropoietin production in rats. | Journal of physiological anthropology 20090901 |
| Metallothionein alleviates oxidative stress-induced endoplasmic reticulum stress and myocardial dysfunction. | Journal of molecular and cellular cardiology 20090801 |
| Nrf2 is involved in inhibiting Tat-induced HIV-1 long terminal repeat transactivation. | Free radical biology & medicine 20090801 |
| Role of gamma-glutamyl transpeptidase in redox regulation of K+ channel remodeling in postmyocardial infarction rat hearts. | American journal of physiology. Cell physiology 20090801 |
| Plasmodium falciparum: effect of Solanum nudum steroids on thiol contents and beta-hematin formation in parasitized erythrocytes. | Experimental parasitology 20090801 |
| Inhibition of natriuretic factors increases blood pressure in rats. | American journal of physiology. Renal physiology 20090801 |
| The effects of N-acetyl cysteine, buthionine sulfoximine, diethyldithiocarbamate or 3-amino-1,2,4-triazole on antimycin A-treated Calu-6 lung cells in relation to cell growth, reactive oxygen species and glutathione. | Oncology reports 20090801 |
| The effects of buthionine sulfoximine, diethyldithiocarbamate or 3-amino-1,2,4-triazole on propyl gallate-treated HeLa cells in relation to cell growth, reactive oxygen species and glutathione. | International journal of molecular medicine 20090801 |
| Protective mechanism of quercetin and rutin using glutathione metabolism on HO-induced oxidative stress in HepG2 cells. | Annals of the New York Academy of Sciences 20090801 |
| Subapoptogenic oxidative stress strongly increases the activity of the glycolytic key enzyme glyceraldehyde 3-phosphate dehydrogenase. | Annals of the New York Academy of Sciences 20090801 |
| Increase in thiol oxidative stress via glutathione reductase inhibition as a novel approach to enhance cancer sensitivity to X-ray irradiation. | Free radical biology & medicine 20090715 |
| Curcumin eliminates leptin's effects on hepatic stellate cell activation via interrupting leptin signaling. | Endocrinology 20090701 |
| Metabolism-dependent hepatotoxicity of amodiaquine in glutathione-depleted mice. | Archives of toxicology 20090701 |
| Arsenic induces telomerase expression and maintains telomere length in human cord blood cells. | Toxicology 20090616 |
| Transcription factor Nrf2 mediates an adaptive response to sulforaphane that protects fibroblasts in vitro against the cytotoxic effects of electrophiles, peroxides and redox-cycling agents. | Toxicology and applied pharmacology 20090615 |
| Glutathione depletion by buthionine sulfoximine induces oxidative damage to DNA in organs of rabbits in vivo. | Biochemistry 20090609 |
| Relationship between oxidative stress and hepatic glutathione levels in ethanol-mediated apoptosis of polarized hepatic cells. | World journal of gastroenterology 20090607 |
| Antioxidant responses and NRF2 in synergistic developmental toxicity of PAHs in zebrafish. | Toxicological sciences : an official journal of the Society of Toxicology 20090601 |
| Glutamine attenuates lipopolysaccharide-induced acute lung injury. | Nutrition (Burbank, Los Angeles County, Calif.) 20090601 |
| In vivo GSH depletion induces c-myc expression by modulation of chromatin protein complexes. | Free radical biology & medicine 20090601 |
| Oxidative stress and sodium methyldithiocarbamate-induced modulation of the macrophage response to lipopolysaccharide in vivo. | Toxicological sciences : an official journal of the Society of Toxicology 20090601 |
| Characterization of antioxidant protection of cultured neural progenitor cells (NPC) against methylmercury (MeHg) toxicity. | The Journal of toxicological sciences 20090601 |
| Cytotoxicity and chromosomal aberrations induced by acrylamide in V79 cells: role of glutathione modulators. | Mutation research 20090531 |
| Differential protection by human glutathione S-transferase P1 against cytotoxicity of benzo[a]pyrene, dibenzo[a,l]pyrene, or their dihydrodiol metabolites, in bi-transgenic cell lines that co-express rat versus human cytochrome P4501A1. | Chemico-biological interactions 20090515 |
| Detection of benzo(a)pyrene diol epoxide-DNA adducts in mononuclear white blood cells by CE immunoassay and its application to studying the effect of glutathione depletion. | Electrophoresis 20090501 |
| Darinaparsin induces a unique cellular response and is active in an arsenic trioxide-resistant myeloma cell line. | Molecular cancer therapeutics 20090501 |
| Impact of glutathione on the gene expression of exoY and exoS in Pseudomonas aeruginosa. | Wei sheng wu xue bao = Acta microbiologica Sinica 20090501 |
| Influence of glutathione levels on radiation-induced chromosomal DNA damage and repair in human peripheral lymphocytes. | Mutation research 20090430 |
| The antioxidant glutathione in the fish cell lines EPC and BCF-2: response to model pro-oxidants as measured by three different fluorescent dyes. | Toxicology in vitro : an international journal published in association with BIBRA 20090401 |
| Is propylene oxide induced cell proliferation in rat nasal respiratory epithelium mediated by a severe depletion of water-soluble non-protein thiol? | Toxicology letters 20090328 |
| Redox modulation at the peripheral site alters nociceptive transmission in vivo. | Clinical and experimental pharmacology & physiology 20090301 |
| Early sensing and gene expression profiling under a low dose of cadmium exposure. | Biochimie 20090301 |
| Astrocyte-secreted GDNF and glutathione antioxidant system protect neurons against 6OHDA cytotoxicity. | Neurobiology of disease 20090301 |
| Potential of l-buthionine sulfoximine to enhance the apoptotic action of estradiol to reverse acquired antihormonal resistance in metastatic breast cancer. | The Journal of steroid biochemistry and molecular biology 20090301 |
| A(1) and A(3) adenosine receptors alter glutathione status in an organ-specific manner and influence the changes after inhibition of gamma-glutamylcysteine ligase. | Free radical research 20090301 |
| Carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone (FCCP) as an O2(*-) generator induces apoptosis via the depletion of intracellular GSH contents in Calu-6 cells. | Lung cancer (Amsterdam, Netherlands) 20090201 |
| Involvement of oxidative stress and activation of aryl hydrocarbon receptor in elevation of CYP1A1 expression and activity in lung cells and tissues by arsenic: an in vitro and in vivo study. | Toxicological sciences : an official journal of the Society of Toxicology 20090201 |
| Cyclophosphamide-evoked heart failure involves pronounced co-suppression of cytoplasmic thioredoxin reductase activity and non-protein free thiol level. | European journal of heart failure 20090201 |
| Cisplatin combined with zidovudine enhances cytotoxicity and oxidative stress in human head and neck cancer cells via a thiol-dependent mechanism. | Free radical biology & medicine 20090115 |
| Oxidative, multistep activation of the noncanonical NF-kappaB pathway via disulfide Bcl-3/p50 complex. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090101 |
| Upregulation of cellular glutathione by 3H-1,2-dithiole-3-thione as a possible treatment strategy for protecting against acrolein-induced neurocytotoxicity. | Neurotoxicology 20090101 |
| Expression of human papilloma virus type 16 E5 protein in amelanotic melanoma cells regulates endo-cellular pH and restores tyrosinase activity. | Journal of experimental & clinical cancer research : CR 20090101 |
| Intestinal barrier function in response to abundant or depleted mucosal glutathione in Salmonella-infected rats. | BMC physiology 20090101 |
| 'Shock and kill' effects of class I-selective histone deacetylase inhibitors in combination with the glutathione synthesis inhibitor buthionine sulfoximine in cell line models for HIV-1 quiescence. | Retrovirology 20090101 |
| The depletion of nuclear glutathione impairs cell proliferation in 3t3 fibroblasts. | PloS one 20090101 |
| Evaluation of lenticular antioxidant and redox system components in the lenses of acetyl-L-carnitine treatment in BSO-induced glutathione deprivation. | Molecular vision 20090101 |
| Brefeldin A activates CHOP promoter at the AARE, ERSE and AP-1 elements. | Molecular and cellular biochemistry 20081201 |
| Characterization of demethylation of methylmercury in cultured astrocytes. | Chemosphere 20081201 |
| Participation of glutathione in the elimination of Porphyromonas gingivalis in vivo. | Oral microbiology and immunology 20081201 |
| Loss of biphasic effect on Na/K-ATPase activity by angiotensin II involves defective angiotensin type 1 receptor-nitric oxide signaling. | Hypertension (Dallas, Tex. : 1979) 20081201 |
| A reducing environment stabilizes HIF-2alpha in SH-SY5Y cells under hypoxic conditions. | FEBS letters 20081126 |
| Adaptive response to GSH depletion and resistance to L-buthionine-(S,R)-sulfoximine: involvement of Nrf2 activation. | Molecular and cellular biochemistry 20081101 |
| Prevention of methylmercury-induced mitochondrial depolarization, glutathione depletion and cell death by 15-deoxy-delta-12,14-prostaglandin J(2). | Neurotoxicology 20081101 |
| Laminar shear stress inhibits lipid peroxidation induced by high glucose plus arachidonic acid in endothelial cells. | American journal of physiology. Heart and circulatory physiology 20081101 |
| Modulation of reactive oxygen species by antioxidants in chronic myeloid leukemia cells enhances imatinib sensitivity through survivin downregulation. | Anti-cancer drugs 20081101 |
| Low glutathione level favors formation of DNA adducts to 4-hydroxy-2(E)-nonenal, a major lipid peroxidation product. | Chemical research in toxicology 20081101 |
| Importance of glutathione in the nodulation process of peanut (Arachis hypogaea). | Physiologia plantarum 20081001 |
| Manipulation of oxidative stress to induce cell death in Ewing's sarcoma family of tumours. | European journal of cancer (Oxford, England : 1990) 20081001 |
| The hepatotoxic metabolite of acetaminophen directly activates the Keap1-Nrf2 cell defense system. | Hepatology (Baltimore, Md.) 20081001 |
| RLIP76 in defense of radiation poisoning. | International journal of radiation oncology, biology, physics 20081001 |
| Glutamine reduces TNF-alpha by enhancing glutathione synthesis in lipopolysaccharide-stimulated alveolar epithelial cells of rats. | Inflammation 20081001 |
| Effect of glutathione (GSH) depletion on DNA damage and blood chemistry in aged and young rats. | The Journal of toxicological sciences 20081001 |
| A carbazole derivative protects cells against endoplasmic reticulum (ER) stress and glutathione depletion. | Journal of pharmacological sciences 20081001 |
| Effects of human Werner helicase on intrachromosomal homologous recombination mediated DNA deletions in mice. | Mutation research 20080926 |
| Elevated glutathione levels confer cellular sensitization to cisplatin toxicity by up-regulation of copper transporter hCtr1. | Molecular pharmacology 20080901 |
| Elevated GSH level increases cadmium resistance through down-regulation of Sp1-dependent expression of the cadmium transporter ZIP8. | Molecular pharmacology 20080901 |
| Oxidative stress-induced renal angiotensin AT1 receptor upregulation causes increased stimulation of sodium transporters and hypertension. | American journal of physiology. Renal physiology 20080901 |
| Differential effects of ifosfamide on dendritic cell-mediated stimulation of T cell interleukin-2 production, natural killer cell cytotoxicity and interferon-gamma production. | Clinical and experimental immunology 20080901 |
| Induction of apoptosis in arsenic trioxide-treated lung cancer A549 cells by buthionine sulfoximine. | Molecules and cells 20080831 |
| Allicin inhibits cell growth and induces apoptosis through the mitochondrial pathway in HL60 and U937 cells. | The Journal of nutritional biochemistry 20080801 |
| Protective effect of thioredoxins 1 and 2 in retinal ganglion cells after optic nerve transection and oxidative stress. | Investigative ophthalmology & visual science 20080801 |
| Reversal of oxidative stress-induced anxiety by inhibition of phosphodiesterase-2 in mice. | The Journal of pharmacology and experimental therapeutics 20080801 |
| Regulation of the susceptibility to oxidative stress by cysteine availability in pancreatic beta-cells. | American journal of physiology. Cell physiology 20080801 |
| Oxidative stress regulates type 3 deiodinase and type 2 deiodinase in cultured rat astrocytes. | Endocrinology 20080701 |
| alpha(v)beta(3) Integrin-mediated drug resistance in human laryngeal carcinoma cells is caused by glutathione-dependent elimination of drug-induced reactive oxidative species. | Molecular pharmacology 20080701 |
| Buthionine sulfoximine (BSO)-mediated improvement in cultured embryo quality in vitro entails changes in ascorbate metabolism, meristem development and embryo maturation. | Planta 20080701 |
| Adaptation to chronic MG132 reduces oxidative toxicity by a CuZnSOD-dependent mechanism. | Journal of neurochemistry 20080701 |
| Alkenyl group is responsible for the disruption of microtubule network formation in human colon cancer cell line HT-29 cells. | Carcinogenesis 20080701 |
| Increased metal tolerance in Salix by nicotinamide and nicotinic acid. | Plant physiology and biochemistry : PPB 20080701 |
| Metallothionein alleviates glutathione depletion-induced oxidative cardiomyopathy in murine hearts. | Critical care medicine 20080701 |
| Enhancement of arsenic trioxide-induced apoptosis in HeLa cells by diethyldithiocarbamate or buthionine sulfoximine. | International journal of oncology 20080701 |
| Heme-oxygenase 1 gene expression is a marker for hexavalent chromium-induced stress and toxicity in human dermal fibroblasts. | Toxicological sciences : an official journal of the Society of Toxicology 20080601 |
| Combined use of sodium borocaptate and buthionine sulfoximine in boron neutron capture therapy enhanced tissue boron uptake and delayed tumor growth in a rat subcutaneous tumor model. | Cancer letters 20080518 |
| Fullerene C60 exposure elicits an oxidative stress response in embryonic zebrafish. | Toxicology and applied pharmacology 20080515 |
| Effect of glutathione depletion on Leydig cell steroidogenesis in young and old brown Norway rats. | Endocrinology 20080501 |
| Markers of electrophilic stress caused by chemically reactive metabolites in human hepatocytes. | Drug metabolism and disposition: the biological fate of chemicals 20080501 |
| Epigallocatechin-3-gallate inhibits growth of activated hepatic stellate cells by enhancing the capacity of glutathione synthesis. | Molecular pharmacology 20080501 |
| 15-Deoxy-delta12,14-prostaglandin-J(2) up-regulates cyclooxygenase-2 but inhibits prostaglandin-E(2) production through a thiol antioxidant-sensitive mechanism. | Pharmacological research 20080501 |
| Comparison of the effects of buthioninesulfoximine and phorone on the metabolism of sulfur-containing amino acids in rat liver. | Biochemical and biophysical research communications 20080418 |
| Chronic oxidative stress induces a tissue-specific reduction in telomere length in CAST/Ei mice. | Free radical biology & medicine 20080415 |
| Ascorbate interacts with reduced glutathione to scavenge phenoxyl radicals in HL60 cells. | Free radical biology & medicine 20080415 |
| Potentiation of arsenic trioxide cytotoxicity by Parthenolide and buthionine sulfoximine in murine and human leukemic cells. | Cancer chemotherapy and pharmacology 20080401 |
| Modulation of trabectedin (ET-743) hepatobiliary disposition by multidrug resistance-associated proteins (Mrps) may prevent hepatotoxicity. | Toxicology and applied pharmacology 20080401 |
| Novel functions of the alpha-ketoglutarate dehydrogenase complex may mediate diverse oxidant-induced changes in mitochondrial enzymes associated with Alzheimer's disease. | Biochimica et biophysica acta 20080401 |
| [Possible effects of ingredients in foods on brain function]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20080401 |
| A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons. | Free radical biology & medicine 20080315 |
| The cystine/cysteine cycle: a redox cycle regulating susceptibility versus resistance to cell death. | Oncogene 20080306 |
| The role of redox-sensitive transcription factors NF-kappaB and AP-1 in the modulation of the Cyp1a1 gene by mercury, lead, and copper. | Free radical biology & medicine 20080301 |
| Curcumin treatment alleviates the effects of glutathione depletion in vitro and in vivo: therapeutic implications for Parkinson's disease explained via in silico studies. | Free radical biology & medicine 20080301 |
| Supplementation with antioxidants fails to increase the total antioxidant capacity of several cell lines in culture. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20080301 |
| The influence of glutathione modulators on the course of Leishmania major infection in susceptible and resistant mice. | Parasite immunology 20080301 |
| [Arsenic trioxide combined with buthionine sulfoximine enhances apoptosis in multidrug-resistant human leukemia K562/ADM cells in vitro]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20080301 |
| Changes in antioxidant defense systems induced by thiram in V79 Chinese hamster fibroblasts. | Toxicology in vitro : an international journal published in association with BIBRA 20080201 |
| Synergistic toxicity induced by prolonged glutathione depletion and inhibition of nuclear factor-kappaB signaling in liver cells. | Toxicology in vitro : an international journal published in association with BIBRA 20080201 |
| Glucose-6-phosphate dehydrogenase plays a central role in modulating reduced glutathione levels in reed callus under salt stress. | Planta 20080201 |
| Activation of Nrf2-mediated oxidative stress response in macrophages by hypochlorous acid. | Toxicology and applied pharmacology 20080201 |
| Decreased glutathione levels potentiate the apoptotic efficacy of selenium: possible involvement of p38 and JNK MAPKs--in vitro studies. | Molecular and cellular biochemistry 20080201 |
| Mechanisms of BSO (L-buthionine-S,R-sulfoximine)-induced cytotoxic effects in neuroblastoma. | Free radical biology & medicine 20080201 |
| Oxidative stress causes renal dopamine D1 receptor dysfunction and salt-sensitive hypertension in Sprague-Dawley rats. | Hypertension (Dallas, Tex. : 1979) 20080201 |
| Ferulic acid attenuated cognitive deficits and increase in carbonyl proteins induced by buthionine-sulfoximine in mice. | Neuroscience letters 20080110 |
| Localization and thiol dependancy of endogenous nitro compounds-mediating urethral photo-relaxation. | Pflugers Archiv : European journal of physiology 20080101 |
| Neurotoxicity from glutathione depletion is mediated by Cu-dependent p53 activation. | Free radical biology & medicine 20080101 |
| Upregulation of endothelial and inducible nitric oxide synthase expression by reactive oxygen species. | American journal of hypertension 20080101 |
| GSH loss per se does not affect neuroblastoma survival and is not genotoxic. | International journal of oncology 20080101 |
| Mrp2-related efflux of scutellarin in the intestinal absorption in rats. | Die Pharmazie 20080101 |
| Implications of the involvement of the endoplasmic reticulum stress pathway in drug-induced apoptosis. | Anticancer research 20080101 |
| Modulation of fenthion-induced oxidative effects by BSO in the liver of Cyprinus carpio L. | Drug and chemical toxicology 20080101 |
| NF-kappaB and AP-1 are key signaling pathways in the modulation of NAD(P)H:quinone oxidoreductase 1 gene by mercury, lead, and copper. | Journal of biochemical and molecular toxicology 20080101 |
| Boric acid inhibits LPS-induced TNF-alpha formation through a thiol-dependent mechanism in THP-1 cells. | Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 20080101 |
| Reduction of vesicant toxicity by butylated hydroxyanisole in A-431 skin cells. | Cutaneous and ocular toxicology 20080101 |
| Buthionine sulfoximine sensitizes antihormone-resistant human breast cancer cells to estrogen-induced apoptosis. | Breast cancer research : BCR 20080101 |
| Ifosfamide induces acute renal failure via inhibition of the thioredoxin reductase activity. | Free radical biology & medicine 20071215 |
| Depletion of glutathione by buthionine sulfoximine decreases random-pattern skin flap viability in rats. | The Journal of surgical research 20071201 |
| Effects of buthionine sulfoximine treatment on diaphragm contractility and SR Ca2+ pump function in rats. | Journal of applied physiology (Bethesda, Md. : 1985) 20071201 |
| Physiological role of free radicals in skeletal muscles. | Journal of applied physiology (Bethesda, Md. : 1985) 20071201 |
| Phenol-induced in vivo oxidative stress in skin: evidence for enhanced free radical generation, thiol oxidation, and antioxidant depletion. | Chemical research in toxicology 20071201 |
| Acute antihypertensive action of Tempol in the spontaneously hypertensive rat. | American journal of physiology. Heart and circulatory physiology 20071201 |
| Reduction of cis,trans,cis-[PtCl2(OCOCH3)2(NH3)2] by aqueous extracts of cancer cells. | Journal of medicinal chemistry 20071115 |
| Cytotoxicity of formaldehyde on human osteoblastic cells is related to intracellular glutathione levels. | Journal of biomedical materials research. Part B, Applied biomaterials 20071101 |
| Activation of nuclear factor (erythroid-2 like) factor 2 by toxic bile acids provokes adaptive defense responses to enhance cell survival at the emergence of oxidative stress. | Molecular pharmacology 20071101 |
| Glutathione depletion activates mitogen-activated protein kinase (MAPK) pathways that display organ-specific responses and brain protection in mice. | Free radical biology & medicine 20071101 |
| Accumulation of hypoxia-inducible factor-1alpha through a novel electrophilic, thiol antioxidant-sensitive mechanism. | Cellular signalling 20071001 |
| The mode of cisplatin-induced cell death in CYP2E1-overexpressing HepG2 cells: modulation by ERK, ROS, glutathione, and thioredoxin. | Free radical biology & medicine 20071001 |
| Buthionine sulfoximine inhibits cytopathic effects and apoptosis induced by infection with AIK-HDC strain of measles virus. | Iranian biomedical journal 20071001 |
| Atrial glutathione content, calcium current, and contractility. | The Journal of biological chemistry 20070921 |
| Lack of mitochondrial depolarization by oxidative stress is associated with resistance to buthionine sulfoximine in acute lymphoblastic leukemia cells. | Leukemia research 20070901 |
| Redox control of G(1)/S cell cycle regulators during nitric oxide-mediated cell cycle arrest. | Journal of cellular physiology 20070901 |
| Control of extracellular cysteine/cystine redox state by HT-29 cells is independent of cellular glutathione. | American journal of physiology. Regulatory, integrative and comparative physiology 20070901 |
| Novel use of the fluorescent dye 5-(and-6)-chloromethyl SNARF-1 acetate for the measurement of intracellular glutathione in leukemic cells and primary lymphocytes. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20070901 |
| Protective effects of 15-deoxy-Delta12,14-prostaglandin J2 against glutamate-induced cell death in primary cortical neuron cultures: induction of adaptive response and enhancement of cell tolerance primarily through up-regulation of cellular glutathione. | Journal of neurochemistry 20070901 |
| Involvement of glutathione in puberty and FSH release. | Neuroscience letters 20070809 |
| Role of endogenous glutathione in the secondary damage in experimental spinal cord injury in mice. | Neuroscience letters 20070809 |
| Meal cysteine improves postprandial glucose control in rats fed a high-sucrose meal. | The Journal of nutritional biochemistry 20070801 |
| Multidrug resistance protein 1 (MRP1) in rabbit conjunctival epithelial cells: its effect on drug efflux and its regulation by adenoviral infection. | Pharmaceutical research 20070801 |
| De novo synthesis of glutathione is a prerequisite for curcumin to inhibit hepatic stellate cell (HSC) activation. | Free radical biology & medicine 20070801 |
| Effects of BSO, GSH, Vit-C and DMPS on the nephrotoxicity of mercury. | Toxicology and industrial health 20070801 |
| Human p53 is inhibited by glutathionylation of cysteines present in the proximal DNA-binding domain during oxidative stress. | Biochemistry 20070703 |
| Hypoxic remodelling of Ca2+signalling in SH-SY5Y cells: influence of glutathione. | Neuroreport 20070702 |
| Glutathione and glutathione-linked enzymes in normal human aortic smooth muscle cells: chemical inducibility and protection against reactive oxygen and nitrogen species-induced injury. | Molecular and cellular biochemistry 20070701 |
| Cyclophosphamide-induced apoptosis in COV434 human granulosa cells involves oxidative stress and glutathione depletion. | Toxicological sciences : an official journal of the Society of Toxicology 20070701 |
| The interaction of chromium (VI) with macrophages: depletion of glutathione and inhibition of glutathione reductase. | Toxicology 20070701 |
| The quercetin paradox. | Toxicology and applied pharmacology 20070701 |
| [The effect of arsenic trioxide (As2O3) combined with BSO on K562/ADM cell and its mechanisms]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20070701 |
| Benzo[a]pyrene-induced elevation of GSH level protects against oxidative stress and enhances xenobiotic detoxification in human HepG2 cells. | Toxicology 20070603 |
| L-Buthionine (S,R) sulfoximine depletes hepatic glutathione but protects against ethanol-induced liver injury. | Alcoholism, clinical and experimental research 20070601 |
| Induction of colon tumorigenesis by glutathione depletion in p53-knock-out mice. | International journal of oncology 20070601 |
| [Oxidative stress on idiopathic osteonecrosis]. | Clinical calcium 20070601 |
| Enhanced Bcr-Abl-specific antileukemic activity of arsenic trioxide (Trisenox) through glutathione-depletion in imatinib-resistant cells. | Haematologica 20070601 |
| Role for glutathione in the hyposensitivity of LPS-pretreated mice to LPS anorexia. | European cytokine network 20070601 |
| Curcumin-induced GADD153 upregulation: modulation by glutathione. | Journal of cellular biochemistry 20070515 |
| Glutathione depletion induces differential apoptosis in cells of mouse retina, in vivo. | Neuroscience letters 20070507 |
| Differential effects of apolipoprotein E3 and E4 on markers of oxidative status in macrophages. | The British journal of nutrition 20070501 |
| Deficient peroxide detoxification underlies the susceptibility of oligodendrocyte progenitors to dopamine toxicity. | Neuropharmacology 20070501 |
| Oxidative stress causes renal dopamine D1 receptor dysfunction and hypertension via mechanisms that involve nuclear factor-kappaB and protein kinase C. | Journal of the American Society of Nephrology : JASN 20070501 |
| Influence of glutathione on the induction of chromosome aberrations, delay in cell cycle kinetics and cell cycle regulator proteins in irradiated mouse bone marrow cells. | International journal of radiation biology 20070501 |
| Chemoinformatics analysis identifies cytotoxic compounds susceptible to chemoresistance mediated by glutathione and cystine/glutamate transport system xc-. | Journal of medicinal chemistry 20070419 |
| Manipulation of energy and redox states in the C6 glioma cells by buthionine sulfoxamine and N-acetylcysteine and the effect on cell survival to cadmium toxicity. | Cellular and molecular biology (Noisy-le-Grand, France) 20070415 |
| Applications of DL-buthionine-[S,R]-sulfoximine deplete cellular glutathione and improve white spruce (Picea glauca) somatic embryo development. | Plant cell reports 20070401 |
| Expression and function of cystine/glutamate transporter in neutrophils. | Journal of leukocyte biology 20070401 |
| Effects of a bacterial lipid byproduct on human pulp fibroblasts in vitro. | Journal of endodontics 20070401 |
| Metabotropic glutamate receptor 3 protects neurons from glucose-induced oxidative injury by increasing intracellular glutathione concentration. | Journal of neurochemistry 20070401 |
| 2-Deoxy-D-glucose combined with cisplatin enhances cytotoxicity via metabolic oxidative stress in human head and neck cancer cells. | Cancer research 20070401 |
| Characterization of natural antimony resistance in Leishmania donovani isolates. | The American journal of tropical medicine and hygiene 20070401 |
| Chalcone inhibits the activation of NF-kappaB and STAT3 in endothelial cells via endogenous electrophile. | Life sciences 20070320 |
| Polycyclic aromatic hydrocarbon (PAH) metabolizing enzyme activities in human lung, and their inducibility by exposure to naphthalene, phenanthrene, pyrene, chrysene, and benzo(a)pyrene as shown in the rat lung and liver. | Archives of toxicology 20070301 |
| Stimulation of colonic mucosal growth associated with oxidized redox status in rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20070301 |
| Multidrug resistance related protein (ABCC1) and its role on nitrite production by the murine macrophage cell line RAW 264.7. | Biochemical pharmacology 20070301 |
| Role of glutathione in apoptosis induced by radiation as determined by 1H MR spectra of cultured tumor cells. | Radiation research 20070301 |
| A fluorescence microplate cytotoxicity assay with a 4-log dynamic range that identifies synergistic drug combinations. | Molecular cancer therapeutics 20070301 |
| Differential expression of heat shock protein mRNAs under in vivo glutathione depletion in the mouse retina. | Neuroscience letters 20070221 |
| Metabolism of glutathione in tumour cells as evidenced by 1H MRS. | FEBS letters 20070220 |
| Depletion of reduced glutathione enhances motor neuron degeneration in vitro and in vivo. | Neuroscience 20070209 |
| Buthionine sulfoximine causes endothelium dependent hyper-relaxation and hypoadiponectinemia. | Life sciences 20070206 |
| GSH-dependent regulation of Fas-mediated caspase-8 activation by acrolein. | FEBS letters 20070206 |
| The role of glutathione in the regulation of nucleotide excision repair during oxidative stress. | Toxicology letters 20070205 |
| Increased expression of the MGMT repair protein mediated by cysteine prodrugs and chemopreventative natural products in human lymphocytes and tumor cell lines. | Carcinogenesis 20070201 |
| Apoptosis induced by crocidolite asbestos in human lung epithelial cells involves inactivation of Akt and MAPK pathways. | Apoptosis : an international journal on programmed cell death 20070201 |
| Dang-Gui Buxue Tang protects against oxidant injury by enhancing cellular glutathione in H9c2 cells: role of glutathione synthesis and regeneration. | Planta medica 20070201 |
| Upregulation of endogenous glutathione system by 3H-1,2-dithiole-3-thione in pancreatic RINm5F beta-cells as a novel strategy for protecting against oxidative beta-cell injury. | Free radical research 20070201 |
| Effect of various radical generators on insulin-dependent regulation of hepatic gene expression. | Bioscience, biotechnology, and biochemistry 20070101 |
| Co-operative effect of glutathione depletion and selenium induced oxidative stress on API and NFkB expression in testicular cells in vitro: insights to regulation of spermatogenesis. | Biological research 20070101 |
| Resveratrol affords protection against peroxynitrite-mediated endothelial cell death: A role for intracellular glutathione. | Chemico-biological interactions 20061215 |
| Glutathione peroxidase 1 and a high cellular glutathione concentration are essential for effective organic hydroperoxide detoxification in astrocytes. | Glia 20061201 |
| Buthionine sulfoximine enhancement of arsenic trioxide-induced apoptosis in leukemia and lymphoma cells is mediated via activation of c-Jun NH2-terminal kinase and up-regulation of death receptors. | Cancer research 20061201 |
| Oxidative upregulation of Bcl-2 in healthy lymphocytes. | Annals of the New York Academy of Sciences 20061201 |
| Ascorbate is a pro-oxidant in chromium-treated human lung cells. | Mutation research 20061107 |
| Metal(loid)s and radionuclides cytotoxicity in Saccharomyces cerevisiae. Role of YCF1, glutathione and effect of buthionine sulfoximine. | Biochimie 20061101 |
| Cryptosporidium parvum sporozoites contain glutathione. | Parasitology 20061101 |
| Curcumin inhibits hypoxia-inducible factor-1 by degrading aryl hydrocarbon receptor nuclear translocator: a mechanism of tumor growth inhibition. | Molecular pharmacology 20061101 |
| Depletion of glutathione induces 4-hydroxynonenal protein adducts and hydroxyurea teratogenicity in the organogenesis stage mouse embryo. | The Journal of pharmacology and experimental therapeutics 20061101 |
| Effects of ageing on spermatozoal chromatin and its sensitivity to in vivo and in vitro oxidative challenge in the Brown Norway rat. | Human reproduction (Oxford, England) 20061101 |
| Subcellular compartmentalization of glutathione: correlations with parameters of oxidative stress related to genotoxicity. | Mutagenesis 20061101 |
| Reversible inhibition of mitochondrial complex I activity following chronic dopaminergic glutathione depletion in vitro: implications for Parkinson's disease. | Free radical biology & medicine 20061101 |
| Manganese-induced neurotoxicity is differentially enhanced by glutathione depletion in astrocytoma and neuroblastoma cells. | Neurochemical research 20061101 |
| Influence of the level of gamma-glutamyltranspeptidase activity on the response of poorly and moderately differentiated rhabdomyosarcoma cell lines to all-trans-retinoic acid. | Anti-cancer drugs 20061101 |
| Subchronic chloroform priming protects mice from a subsequently administered lethal dose of chloroform. | Toxicology and applied pharmacology 20061001 |
| Aqueous extract of Trigonella foenum-graecum L. ameliorates additive urotoxicity of buthionine sulfoximine and cyclophosphamide in mice. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20061001 |
| Inducible nitric oxide synthase up-regulation and mitochondrial glutathione depletion mediate cyanide-induced necrosis in mesencephalic cells. | Journal of neuroscience research 20061001 |
| Glutathione is required for efficient production of infectious picornavirus virions. | Virology 20060930 |
| Electron microscopic analysis of glucose-induced endothelial damage in primary culture: possible mechanism and prevention. | Histology and histopathology 20060901 |
| Up-regulation of P-glycoprotein expression by glutathione depletion-induced oxidative stress in rat brain microvessel endothelial cells. | Journal of neurochemistry 20060901 |
| Metallothionein, an endogenous antioxidant, protects against retinal neuron damage in mice. | Investigative ophthalmology & visual science 20060901 |
| Oxidative stress induces phosphoenolpyruvate carboxykinase expression in H4IIE cells. | Bioscience, biotechnology, and biochemistry 20060901 |
| Selenoprotein P protects endothelial cells from oxidative damage by stimulation of glutathione peroxidase expression and activity. | Free radical research 20060901 |
| Influence of cadmium on murine thymocytes: potentiation of apoptosis and oxidative stress. | Toxicology letters 20060820 |
| Thiol regulation of vascular endothelial growth factor-A and its receptors in human retinal pigment epithelial cells. | Biochemical and biophysical research communications 20060811 |
| Upregulation of endothelial heme oxygenase-1 expression through the activation of the JNK pathway by sublethal concentrations of acrolein. | Toxicology and applied pharmacology 20060801 |
| Expression of a truncated tau protein induces oxidative stress in a rodent model of tauopathy. | The European journal of neuroscience 20060801 |
| In vitro and in vivo neuroprotection by gamma-glutamylcysteine ethyl ester against MPTP: relevance to the role of glutathione in Parkinson's disease. | Neuroscience letters 20060710 |
| Regulation of osteoclast differentiation by the redox-dependent modulation of nuclear import of transcription factors. | Cell death and differentiation 20060701 |
| Liquiritigenin, an aglycone of liquiritin in Glycyrrhizae radix, prevents acute liver injuries in rats induced by acetaminophen with or without buthionine sulfoximine. | Chemico-biological interactions 20060610 |
| Consumption of redox energy by glutathione metabolism contributes to hypoxia/ reoxygenation-induced injury in astrocytes. | Molecular and cellular biochemistry 20060601 |
| Inhibition of glutathione synthesis overcomes Bcl-2-mediated topoisomerase inhibitor resistance and induces nonapoptotic cell death via mitochondrial-independent pathway. | Cancer research 20060601 |
| Utilization of a toxicogenomic biomarker for evaluation of chemical-induced glutathione deficiency in rat livers across the GeneChip data of different generations. | Toxicology letters 20060525 |
| Nitrogen monoxide (NO)-mediated iron release from cells is linked to NO-induced glutathione efflux via multidrug resistance-associated protein 1. | Proceedings of the National Academy of Sciences of the United States of America 20060516 |
| Superoxide anions and hydrogen peroxide induce hepatocyte death by different mechanisms: involvement of JNK and ERK MAP kinases. | Journal of hepatology 20060501 |
| Intracellular adaptations of glutathione content in Cucurbita pepo L. induced by treatment with reduced glutathione and buthionine sulfoximine. | Protoplasma 20060501 |
| Regulation of apoptosis/necrosis execution in cadmium-treated human promonocytic cells under different forms of oxidative stress. | Apoptosis : an international journal on programmed cell death 20060501 |
| Effect of 2-methoxyestradiol, buthionine sulfoximine and hydrogen peroxide on the viability of renal carcinoma cell lines (ACHN and ACVB). | Biological & pharmaceutical bulletin 20060501 |
| Evidence of a new dechlorinated ochratoxin A derivative formed in opossum kidney cell cultures after pretreatment by modulators of glutathione pathways: correlation with DNA-adduct formation. | Molecular nutrition & food research 20060501 |
| The novel antioxidant 3-O-caffeoyl-1-methylquinic acid induces Nrf2-dependent phase II detoxifying genes and alters intracellular glutathione redox. | Free radical biology & medicine 20060415 |
| A one-carbon modification of protein lysine associated with elevated oxidative stress in human substantia nigra. | Journal of neurochemistry 20060401 |
| Regulation of nicotine-induced cyclooxygenase-2 protein expression in human gingival fibroblasts. | Acta pharmacologica Sinica 20060401 |
| Reactive oxygen species act through p38 MAPK to limit the lifespan of hematopoietic stem cells. | Nature medicine 20060401 |
| Stem cell aging: what bleach can teach. | Nature medicine 20060401 |
| O(6)-methylguanine DNA-methyltransferase (MGMT) overexpression in melanoma cells induces resistance to nitrosoureas and temozolomide but sensitizes to mitomycin C. | Toxicology and applied pharmacology 20060301 |
| Redox control of K+ channel remodeling in rat ventricle. | Journal of molecular and cellular cardiology 20060301 |
| Oxidative stress by glutathione depletion induces osteonecrosis in rats. | Rheumatology (Oxford, England) 20060301 |
| Opposing effects of glutathione depletion and follicle-stimulating hormone on reactive oxygen species and apoptosis in cultured preovulatory rat follicles. | Endocrinology 20060301 |
| Non-destructive micromethod for MRP1 functional assay in human lung tumor cells. | Archives of toxicology 20060301 |
| Increased cellular glutathione and protection by bone marrow stromal cells account for the resistance of non-acute promylocytic leukemia acute myeloid leukemia cells to arsenic trioxide in vivo. | Leukemia & lymphoma 20060301 |
| Enzymic systems proposed to be involved in the dissimilatory reduction of selenite in the purple non-sulfur bacteria Rhodospirillum rubrum and Rhodobacter capsulatus. | Microbiology (Reading, England) 20060301 |
| Overexpression of CYP2E1 in mitochondria sensitizes HepG2 cells to the toxicity caused by depletion of glutathione. | The Journal of biological chemistry 20060224 |
| Glutathione depletion in vivo enhances contraction and attenuates endothelium-dependent relaxation of isolated rat aorta. | Free radical biology & medicine 20060215 |
| Involvement of NF-kappaB and glutathione in cytotoxic effects of nitric oxide and taxol on human leukemia cells. | Leukemia research 20060201 |
| Glutathione depletion by buthionine sulfoximine induces DNA deletions in mice. | Carcinogenesis 20060201 |
| Minimal ovarian upregulation of glutamate cysteine ligase expression in response to suppression of glutathione by buthionine sulfoximine. | Reproductive toxicology (Elmsford, N.Y.) 20060201 |
| Piceatannol upregulates endothelial heme oxygenase-1 expression via novel protein kinase C and tyrosine kinase pathways. | Pharmacological research 20060201 |
| Mechanisms of gamma-glutamylcysteine ligase regulation. | Biochimica et biophysica acta 20060201 |
| Synaptic plasticity impairment and hypofunction of NMDA receptors induced by glutathione deficit: relevance to schizophrenia. | Neuroscience 20060201 |
| TFAM-dependent and independent dynamics of mtDNA levels in C2C12 myoblasts caused by redox stress. | Biochimica et biophysica acta 20060201 |
| Inhibition of glutamate cysteine ligase activity sensitizes human breast cancer cells to the toxicity of 2-deoxy-D-glucose. | Cancer research 20060201 |
| Beta2-adrenoreceptor agonist-enhanced recovery of locomotor function after spinal cord injury is glutathione dependent. | Journal of neurotrauma 20060201 |
| Antimony trioxide-induced apoptosis is dependent on SEK1/JNK signaling. | Toxicology letters 20060105 |
| Oxidative stress and apoptosis: a new treatment paradigm in cancer. | Frontiers in bioscience : a journal and virtual library 20060101 |
| Beta-amyloid and oxidative stress jointly induce neuronal death, amyloid deposits, gliosis, and memory impairment in the rat brain. | Pharmacology 20060101 |
| Relief of arsenate toxicity by Cd-stimulated phytochelatin synthesis in the green alga Chlamydomonas reinhardtii. | Marine biotechnology (New York, N.Y.) 20060101 |
| Adaptive cellular protection against UVA-1-induced lipid peroxidation in human dermal fibroblasts shows donor-to-donor variability and is glutathione dependent. | Archives of dermatological research 20060101 |
| Glutathione in cancer biology and therapy. | Critical reviews in clinical laboratory sciences 20060101 |
| Direct measurement of the rate of glutathione synthesis in 1-chloro-2,4-dinitrobenzene treated human erythrocytes. | Redox report : communications in free radical research 20060101 |
| Euonymus alatus (Thunb.) Sieb induces apoptosis via mitochondrial pathway as prooxidant in human uterine leiomyomal smooth muscle cells. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20060101 |
| Indirect antioxidant protection against photooxidative processes initiated in retinal pigment epithelial cells by a lipofuscin pigment. | Rejuvenation research 20060101 |
| Schisandrin B-induced increase in cellular glutathione level and protection against oxidant injury are mediated by the enhancement of glutathione synthesis and regeneration in AML12 and H9c2 cells. | BioFactors (Oxford, England) 20060101 |
| [Mechanisms of 232Th effects on Chlorella vulgaris Beljer and modifications of it's toxic effect with caffeine and buthionine sulfoximine]. | Radiatsionnaia biologiia, radioecologiia 20060101 |
| Glutathione depletion modulates gene expression in HepG2 cells via activation of protein kinase C alpha. | Toxicology 20051215 |
| An in vitro approach to detect metabolite toxicity due to CYP3A4-dependent bioactivation of xenobiotics. | Toxicology 20051215 |
| The role of low molecular weight thiols in T lymphocyte proliferation and IL-2 secretion. | Journal of immunology (Baltimore, Md. : 1950) 20051215 |
| Inhibition of interferon-gamma signaling by a mercurio-substituted dihydropsoralen in murine keratinocytes. | Biochemical pharmacology 20051205 |
| Transport deficient (TR-) hyperbilirubinemic rats are resistant to acetaminophen hepatotoxicity. | Biochemical pharmacology 20051205 |
| The role of oxidative stress in the modulation of aryl hydrocarbon receptor-regulated genes by As3+, Cd2+, and Cr6+. | Free radical biology & medicine 20051201 |
| Effect of nitric oxide on gamma-ray-induced micronucleus frequency in RAW264.7 cells. | Radiation research 20051201 |
| Sodium stibogluconate resistance in Leishmania donovani correlates with greater tolerance to macrophage antileishmanial responses and trivalent antimony therapy. | Parasitology 20051201 |
| Protective effect of KR-31378 on oxidative stress in cardiac myocytes. | Archives of pharmacal research 20051201 |
| Synthesis and bioactivity of new phosphorylated R,R'-substituted sulfoximines. | Molecules (Basel, Switzerland) 20051130 |
| Arsenite enhances tumor necrosis factor-alpha-induced expression of vascular cell adhesion molecule-1. | Toxicology and applied pharmacology 20051115 |
| Renal ischemia induces an increase in nitric oxide levels from tissue stores. | American journal of physiology. Regulatory, integrative and comparative physiology 20051101 |
| Metabolic alterations in K562 cells exposed to taxol and tyrphostin AG957: 1H NMR and biochemical studies. | Cell biology international 20051101 |
| Hepatocyte growth factor protects RPE cells from apoptosis induced by glutathione depletion. | Investigative ophthalmology & visual science 20051101 |
| Goniothalamin induces cell cycle-specific apoptosis by modulating the redox status in MDA-MB-231 cells. | European journal of pharmacology 20051017 |
| Aging reduces responsiveness to BSO- and heat stress-induced perturbations of glutathione and antioxidant enzymes. | American journal of physiology. Regulatory, integrative and comparative physiology 20051001 |
| Iron accelerates the conversion of dopamine-oxidized intermediates into melanin and provides protection in SH-SY5Y cells. | Journal of neuroscience research 20051001 |
| Estrogen receptor alpha mediates neuronal differentiation and neuroprotection in PC12 cells: critical role of the A/B domain of the receptor. | Journal of molecular endocrinology 20051001 |
| Pharmacological studies on mechanisms of aminophylline-induced seizures in rats. | Indian journal of experimental biology 20051001 |
| Measurement of radical-scavenging ability in hepatic metallothionein of rat using in vivo electron spin resonance spectroscopy. | Toxicology 20050915 |
| Interaction of radiation- and bleomycin-induced lesions and influence of glutathione level on the interaction. | Mutagenesis 20050901 |
| [Experimental study on the effects of BSO, GSH, vitamin C and DMPS on the nephrotoxicity induced by mercury]. | Wei sheng yan jiu = Journal of hygiene research 20050901 |
| Characterization and regulation of the gene encoding monothiol glutaredoxin 3 in the fission yeast Schizosaccharomyces pombe. | Molecules and cells 20050831 |
| Cystine-glutamate transporter SLC7A11 in cancer chemosensitivity and chemoresistance. | Cancer research 20050815 |
| Cardiomyocyte apoptosis induced by short-term diabetes requires mitochondrial GSH depletion. | American journal of physiology. Heart and circulatory physiology 20050801 |
| Role of glutathione in reproductive tract secretions on mouse preimplantation embryo development. | Biology of reproduction 20050801 |
| Preventive mechanism of cellular glutathione in monomethylarsonic acid-induced cytolethality. | Toxicology and applied pharmacology 20050801 |
| Differential effects of l-DOPA on monoamine metabolism, cell survival and glutathione production in midbrain neuronal-enriched cultures from parkin knockout and wild-type mice. | Journal of neurochemistry 20050801 |
| Hydrogen sulfide protects colon cancer cells from chemopreventative agent beta-phenylethyl isothiocyanate induced apoptosis. | World journal of gastroenterology 20050714 |
| Garlic oil and DDB, comprised in a pharmaceutical composition for the treatment of patients with viral hepatitis, prevents acute liver injuries potentiated by glutathione deficiency in rats. | Chemico-biological interactions 20050630 |
| Chronic depletion of glutathione (GSH) and minimal modification of LDL in vivo: its prevention by glutathione mono ester (GME) therapy. | Biochimica et biophysica acta 20050630 |
| Modulatory effect of glutathione status and antioxidants on methylmercury-induced free radical formation in primary cultures of cerebral astrocytes. | Brain research. Molecular brain research 20050613 |
| Apoptosis vs. necrosis: glutathione-mediated cell death during rewarming of rat hepatocytes. | Biochimica et biophysica acta 20050610 |
| Effect of ribose cysteine pretreatment on hepatic and renal acetaminophen metabolite formation and glutathione depletion. | Basic & clinical pharmacology & toxicology 20050601 |
| Gamma-glutamylcysteine synthetase and L-buthionine-(S,R)-sulfoximine: a new selection strategy for gene-transduced neural and hematopoietic stem/progenitor cells. | Human gene therapy 20050601 |
| Selenoprotein W as molecular target of methylmercury in human neuronal cells is down-regulated by GSH depletion. | Biochemical and biophysical research communications 20050520 |
| Dental adhesive compounds alter glutathione levels but not glutathione redox balance in human THP-1 monocytic cells. | Journal of biomedical materials research. Part B, Applied biomaterials 20050501 |
| Hydrogen peroxide overload increases adriamycin-induced apoptosis of SaOS(2)FM, a manganese superoxide dismutase-overexpressing human osteosarcoma cell line. | International journal of oncology 20050501 |
| Reactive oxygen species mediate high glucose-induced plasminogen activator inhibitor-1 up-regulation in mesangial cells and in diabetic kidney. | Kidney international 20050501 |
| Role of glutathione in intracellular amyloid-alpha precursor protein/carboxy-terminal fragment aggregation and associated cytotoxicity. | Journal of neurochemistry 20050501 |
| Gene expression of energy and protein metabolism in hearts of hypertensive nitric oxide- or GSH-depleted mice. | European journal of pharmacology 20050418 |
| Involvement of protein kinase A in cannabinoid receptor-mediated protection from oxidative neuronal injury. | The Journal of pharmacology and experimental therapeutics 20050401 |
| Heme oxygenase-2 protects against glutathione depletion-induced neuronal apoptosis mediated by bilirubin and cyclic GMP. | Current neurovascular research 20050401 |
| Glutathione synthesis in Streptococcus agalactiae. One protein accounts for gamma-glutamylcysteine synthetase and glutathione synthetase activities. | The Journal of biological chemistry 20050325 |
| Reduced clastogenic activity of maleic hydrazide in Vicia faba seedlings grown in a situation of overcrowding stress. | Mutation research 20050307 |
| Manganese potentiates in vitro production of proinflammatory cytokines and nitric oxide by microglia through a nuclear factor kappa B-dependent mechanism. | Toxicological sciences : an official journal of the Society of Toxicology 20050301 |
| Simultaneous and ultrarapid determination of reactive oxygen species and reduced glutathione in apoptotic leukemia cells by microchip electrophoresis. | Electrophoresis 20050301 |
| Super-induction of HO-1 in macrophages stimulated with lipopolysaccharide by prior depletion of glutathione decreases iNOS expression and NO production. | Nitric oxide : biology and chemistry 20050301 |
| Glutathione and homoglutathione play a critical role in the nodulation process of Medicago truncatula. | Molecular plant-microbe interactions : MPMI 20050301 |
| Up-regulation of glutathione biosynthesis in NIH3T3 cells transformed with the ETV6-NTRK3 gene fusion. | Molecules and cells 20050227 |
| Mutagenicity of the mycotoxin patulin in cultured Chinese hamster V79 cells, and its modulation by intracellular glutathione. | Archives of toxicology 20050201 |
| Role of glutathione in reduction of arsenate and of gamma-glutamyltranspeptidase in disposition of arsenite in rats. | Toxicology 20050201 |
| Redox regulation of nerve growth factor-induced neuronal differentiation of PC12 cells through modulation of the nerve growth factor receptor, TrkA. | Archives of biochemistry and biophysics 20050201 |
| Malignant ascites increases the antioxidant ability of human ovarian (SKOV-3) and gastric adenocarcinoma (KATO-III) cells. | Gynecologic oncology 20050201 |
| Pro- and anti-apoptotic roles of c-Jun N-terminal kinase (JNK) in ethanol and acetaldehyde exposed rat hepatocytes. | European journal of pharmacology 20050131 |
| Kinetic characteristics of native gamma-glutamylcysteine ligase in the aging housefly, Musca domestica L. | Biochemical and biophysical research communications 20050121 |
| Differential effects of glucose deprivation on the cellular sensitivity towards photodynamic treatment-based production of reactive oxygen species and apoptosis-induction. | FEBS letters 20050103 |
| Tumor necrosis factor-alpha mediates osteopenia caused by depletion of antioxidants. | Endocrinology 20050101 |
| Glutathione depletion enhances the formation of endogenous cyclic DNA adducts derived from t-4-hydroxy-2-nonenal in rat liver. | Chemical research in toxicology 20050101 |
| Antiapoptotic response to induced GSH depletion: involvement of heat shock proteins and NF-kappaB activation. | Antioxidants & redox signaling 20050101 |
| The responses of Ht22 cells to oxidative stress induced by buthionine sulfoximine (BSO). | BMC neuroscience 20050101 |
| Effect of sulphur mustard on human skin cell lines with differential agent sensitivity. | Journal of applied toxicology : JAT 20050101 |
| Glutathione-related enzymes contribute to resistance of tumor cells and low toxicity in normal organs to artesunate. | In vivo (Athens, Greece) 20050101 |
| Arsenic trioxide circumvents multidrug resistance based on different mechanisms in human leukemia cell lines. | Anticancer research 20050101 |
| Cisplatin-induced cytotoxicity in BSO-exposed renal proximal tubular epithelial cells: sex, age, and species. | Renal failure 20050101 |
| Intracellular glutathione levels determine cell sensitivity to apoptosis induced by the antineoplasic agent N-(4-hydroxyphenyl) retinamide. | Anticancer research 20050101 |
| Two major branches of anti-cadmium defense in the mouse: MTF-1/metallothioneins and glutathione. | Nucleic acids research 20050101 |
| Modes of action of alpha-hederin and thymoquinone, active constituents of Nigella sativa, against HEp-2 cancer cells. | Anticancer research 20050101 |
| The effect of buthionine sulfoximine on the glutathione level in goldfish tissues. | Ukrains'kyi biokhimichnyi zhurnal (1999 ) 20050101 |
| Differential regulation of three genes encoding glutathione S-transferases in Schizosaccharomyces pombe. | Molecules and cells 20041231 |
| Mistargeted MRPdeltaF728 mutant is rescued by intracellular GSH. | FEBS letters 20041203 |
| Enhancement of sodium borocaptate (BSH) uptake by tumor cells induced by glutathione depletion and its radiobiological effect. | Cancer letters 20041108 |
| Differential multidrug resistance-associated protein 1 through 6 isoform expression and function in human intestinal epithelial Caco-2 cells. | The Journal of pharmacology and experimental therapeutics 20041101 |
| Reversible cigarette smoke extract-induced DNA damage in human lung fibroblasts. | American journal of respiratory cell and molecular biology 20041101 |
| Compartmentation of Nrf-2 redox control: regulation of cytoplasmic activation by glutathione and DNA binding by thioredoxin-1. | Toxicological sciences : an official journal of the Society of Toxicology 20041101 |
| Antioxidants and ocular cell type differences in cytoprotection from formic acid toxicity in vitro. | Toxicological sciences : an official journal of the Society of Toxicology 20041101 |
| Biphasic induction of heme oxygenase-1 expression in macrophages stimulated with lipopolysaccharide. | Biochemical pharmacology 20041101 |
| Role of extracellular signal-regulated protein kinase in neuronal cell death induced by glutathione depletion in neuron/glia mesencephalic cultures. | Journal of neurochemistry 20041101 |
| The gamma-glutamylcysteine synthetase and glutathione regulate asbestos-induced expression of activator protein-1 family members and activity. | Cancer research 20041101 |
| Alpha-tocotrienol provides the most potent neuroprotection among vitamin E analogs on cultured striatal neurons. | Neuropharmacology 20041101 |
| Regulation of interleukin-6 expression by arecoline in human buccal mucosal fibroblasts is related to intracellular glutathione levels. | Oral diseases 20041101 |
| Induction of PR-1 accumulation accompanied by runaway cell death in the lsd1 mutant of Arabidopsis is dependent on glutathione levels but independent of the redox state of glutathione. | Plant & cell physiology 20041101 |
| Role of glutathione in the adaptive tolerance to H2O2. | Free radical biology & medicine 20041015 |
| Spatial activities and induction of glutamate-cysteine ligase (GCL) in the postimplantation rat embryo and visceral yolk sac. | Toxicological sciences : an official journal of the Society of Toxicology 20041001 |
| Glutathione depletion up-regulates Bcl-2 in BSO-resistant cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20041001 |
| Progressive iron accumulation induces a biphasic change in the glutathione content of neuroblastoma cells. | Free radical biology & medicine 20041001 |
| Evaluation of glutathione deficiency in rat livers by microarray analysis. | Biochemical pharmacology 20041001 |
| Cystamine increases L-cysteine levels in Huntington's disease transgenic mouse brain and in a PC12 model of polyglutamine aggregation. | Journal of neurochemistry 20041001 |
| N-acetylcysteine enhances multidrug resistance-associated protein 1 mediated doxorubicin resistance. | European journal of clinical investigation 20041001 |
| Free radical formation in cerebral cortical astrocytes in culture induced by methylmercury. | Brain research. Molecular brain research 20040910 |
| The emerging role of reactive oxygen species in cancer therapy. | European journal of cancer (Oxford, England : 1990) 20040901 |
| Glutathione depletion in CYP2E1-expressing liver cells induces toxicity due to the activation of p38 mitogen-activated protein kinase and reduction of nuclear factor-kappaB DNA binding activity. | Molecular pharmacology 20040901 |
| Effect of curcumin on normal and tumor cells: role of glutathione and bcl-2. | Molecular cancer therapeutics 20040901 |
| Argininosuccinate synthetase is reversibly inactivated by S-nitrosylation in vitro and in vivo. | The Journal of biological chemistry 20040827 |
| Glutathione regulates telomerase activity in 3T3 fibroblasts. | The Journal of biological chemistry 20040813 |
| beta-D-Glucoside suppresses tumor necrosis factor-induced activation of nuclear transcription factor kappaB but potentiates apoptosis. | The Journal of biological chemistry 20040806 |
| Topoisomerase I-DNA complexes contribute to arsenic trioxide-induced apoptosis. | The Journal of biological chemistry 20040806 |
| Arabidopsis thaliana glutamate-cysteine ligase: functional properties, kinetic mechanism, and regulation of activity. | The Journal of biological chemistry 20040806 |
| Cysteine/cystine couple is a newly recognized node in the circuitry for biologic redox signaling and control. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040801 |
| Role of glutathione in dimethylarsinic acid-induced apoptosis. | Toxicology and applied pharmacology 20040801 |
| Modulation of resistance to regional chemotherapy in the extremity melanoma model. | Surgery 20040801 |
| Influence of glutathione depletion on plasma membrane cholesterol esterification and on Tc-99m-sestamibi and Tc-99m-tetrofosmin uptakes: a comparative study in sensitive U-87-MG and multidrug-resistant MRP1 human glioma cells. | Cancer biotherapy & radiopharmaceuticals 20040801 |
| Effects of BSO and L-cysteine on drug-induced cytotoxicity in primary cell cultures: drug-, cell type-, and species-specific difference. | Drug and chemical toxicology 20040801 |
| Role for PKC-epsilon in neuronal death induced by oxidative stress. | Biochemical and biophysical research communications 20040730 |
| Pantothenic acid and pantothenol increase biosynthesis of glutathione by boosting cell energetics. | FEBS letters 20040702 |
| Effective treatment of advanced solid tumors by the combination of arsenic trioxide and L-buthionine-sulfoximine. | Cell death and differentiation 20040701 |
| A critical role of glutathione in determining apoptosis sensitivity and resistance in leukemia cells. | Cell death and differentiation 20040701 |
| Redox state regulates HIF-1alpha and its DNA binding and phosphorylation in salmonid cells. | Journal of cell science 20040701 |
| Alteration of cellular phenotype and responses to oxidative stress by manganese superoxide dismutase and a superoxide dismutase mimic in RWPE-2 human prostate adenocarcinoma cells. | Antioxidants & redox signaling 20040601 |
| Effects of cyclophosphamide and buthionine sulfoximine on ovarian glutathione and apoptosis. | Free radical biology & medicine 20040601 |
| Enhancement of arsenic trioxide-induced apoptosis in renal cell carcinoma cells by L-buthionine sulfoximine. | International journal of oncology 20040601 |
| Cysteine but not glutathione modulates the radiosensitivity of human melanoma cells by affecting both survival and DNA damage. | Pigment cell research 20040601 |
| Buthionine sulfoximine inhibits cytopathic effect and apoptosis induced by infection with human echovirus 9. | Archives of virology 20040601 |
| Identification of multidrug resistance-associated protein 1 and glutathione as multidrug resistance mechanisms in human prostate cancer cells: chemosensitization with leukotriene D4 antagonists and buthionine sulfoximine. | BJU international 20040601 |
| Promoting effects of polyunsaturated fatty acids on chromosomal giant DNA fragmentation associated with cell death induced by glutathione depletion. | Free radical research 20040601 |
| Glutamate modulation of human lymphocyte growth: in vitro studies. | Biochemical and biophysical research communications 20040528 |
| Critical roles of intracellular thiols and calcium in parthenolide-induced apoptosis in human colorectal cancer cells. | Cancer letters 20040528 |
| 15-deoxy-delta 12,14-prostaglandin J2 induces heme oxygenase-1 gene expression in a reactive oxygen species-dependent manner in human lymphocytes. | The Journal of biological chemistry 20040521 |
| Validation of Trypanosoma brucei trypanothione synthetase as drug target. | Free radical biology & medicine 20040515 |
| 1-Benzyl-1,2,3,4-tetrahydroisoquinoline, a Parkinsonism-inducing endogenous toxin, increases alpha-synuclein expression and causes nuclear damage in human dopaminergic cells. | Journal of neuroscience research 20040515 |
| JNK activation is a mediator of arsenic trioxide-induced apoptosis in acute promyelocytic leukemia cells. | Blood 20040501 |
| The chemopreventive agent phenethyl isothiocyanate sensitizes cells to Fas-mediated apoptosis. | Carcinogenesis 20040501 |
| Chronic oxidative stress compromises telomere integrity and accelerates the onset of senescence in human endothelial cells. | Journal of cell science 20040501 |
| Glutathione depletion induced by c-Myc downregulation triggers apoptosis on treatment with alkylating agents. | Neoplasia (New York, N.Y.) 20040501 |
| Glutathione depletion modulates methanol, formaldehyde and formate toxicity in cultured rat conceptuses. | Cell biology and toxicology 20040501 |
| GSH depletion enhances adenoviral bax-induced apoptosis in lung cancer cells. | Cancer gene therapy 20040401 |
| Role of reactive oxygen species, glutathione and NF-kappaB in apoptosis induced by 3,4-methylenedioxymethamphetamine ('Ecstasy') on hepatic stellate cells. | Biochemical pharmacology 20040315 |
| Modulation of rat erythrocyte antioxidant defense system by buthionine sulfoximine and its reversal by glutathione monoester therapy. | Biochimica et biophysica acta 20040302 |
| Acute and severe hypobaric hypoxia-induced muscle oxidative stress in mice: the role of glutathione against oxidative damage. | European journal of applied physiology 20040301 |
| Intracellular glutathione in stretch-induced cytokine release from alveolar type-2 like cells. | Respirology (Carlton, Vic.) 20040301 |
| Influence of polyethylene-glycol-superoxide dismutase and combined depletion and repletion of antioxidants on nitrergic relaxation in the pig gastric fundus. | European journal of pharmacology 20040220 |
| Cellular carbonyl stress enhances the expression of plasminogen activator inhibitor-1 in rat white adipocytes via reactive oxygen species-dependent pathway. | The Journal of biological chemistry 20040206 |
| Dipyridamole is neuroprotective for cultured rat embryonic cortical neurons. | Biochemical and biophysical research communications 20040206 |
| Copper-inducible transcription: regulation by metal- and oxidative stress-responsive pathways. | American journal of physiology. Cell physiology 20040201 |
| Increased prooxidant production and enhanced susceptibility to glutathione depletion in HepG2 cells co-expressing HCV core protein and CYP2E1. | Journal of medical virology 20040201 |
| Low brain glutathione and ascorbic acid associated with dopamine uptake inhibition during rat's development induce long-term cognitive deficit: relevance to schizophrenia. | Neurobiology of disease 20040201 |
| Reduced glutathione is a novel regulator of vernalization-induced bolting in the rosette plant Eustoma grandiflorum. | Plant & cell physiology 20040201 |
| [CD59 mutation and DNA oxidative damage in A(L) cells induced by crocidolite fibers]. | Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases 20040201 |
| Heme oxygenase-1 protects HepG2 cells against cytochrome P450 2E1-dependent toxicity. | Free radical biology & medicine 20040201 |
| 12-O-tetradecanoylphorbol-13-acetate may both potentiate and decrease the generation of apoptosis by the antileukemic agent arsenic trioxide in human promonocytic cells. Regulation by extracellular signal-regulated protein kinases and glutathione. | The Journal of biological chemistry 20040130 |
| Oxidative stress mediates toxicity of pyridoxal isonicotinoyl hydrazone analogs. | Archives of biochemistry and biophysics 20040101 |
| The liver-selective nitric oxide donor O2-vinyl 1-(pyrrolidin-1-yl)diazen-1-ium-1,2-diolate (V-PYRRO/NO) protects HepG2 cells against cytochrome P450 2E1-dependent toxicity. | Molecular pharmacology 20040101 |
| Toxicity of glutathione depletion in mesencephalic cultures: a role for arachidonic acid and its lipoxygenase metabolites. | The European journal of neuroscience 20040101 |
| An animal model with relevance to schizophrenia: sex-dependent cognitive deficits in osteogenic disorder-Shionogi rats induced by glutathione synthesis and dopamine uptake inhibition during development. | Neuroscience 20040101 |
| Vitamin E prevents buthionine sulfoximine-induced biochemical disorders in the rat. | The Journal of pharmacy and pharmacology 20040101 |
| Effects of buthionine sulfoximine nifurtimox and benznidazole upon trypanothione and metallothionein proteins in Trypanosoma cruzi. | Biological research 20040101 |
| Effects of the polyacetylene capillin on human tumour cell lines. | Anticancer research 20040101 |
| Protecting against peroxynitrite-mediated cytotoxicity in vascular smooth muscle cells via upregulating endogenous glutathione biosynthesis by 3H-1,2-dithiole-3-thione. | Cardiovascular toxicology 20040101 |
| Involvement of reactive oxygen species in adaphostin-induced cytotoxicity in human leukemia cells. | Blood 20031215 |
| Mechanisms of suppression of neoplastic transformation in vitro by low doses of low LET radiation. | Carcinogenesis 20031201 |
| A novel model of continuous depletion of glutathione in mice treated with L-buthionine (S,R)-sulfoximine. | The Journal of toxicological sciences 20031201 |
| Coordinate induction of glutathione biosynthesis and glutathione-metabolizing enzymes is correlated with salt tolerance in tomato. | FEBS letters 20031120 |
| Induction of cortical cataracts in cultured mouse lenses with H-89, an inhibitor of protein kinase A. | Current eye research 20031101 |
| Adenovirus-mediated expression of Cu/Zn- or Mn-superoxide dismutase protects against CYP2E1-dependent toxicity. | Hepatology (Baltimore, Md.) 20031101 |
| Effects of glutathione on antioxidant response element-mediated gene expression and apoptosis elicited by sulforaphane. | Cancer research 20031101 |
| The role of a formaldehyde dehydrogenase-glutathione pathway in protein S-nitrosation in mammalian cells. | Nitric oxide : biology and chemistry 20031101 |
| Cadmium-induced non-apoptotic cell death mediated by oxidative stress under the condition of sulfhydryl deficiency. | Toxicology letters 20031015 |
| Role of glutathione redox cycle and catalase in defense against oxidative stress induced by endosulfan in adrenocortical cells of rainbow trout (Oncorhynchus mykiss). | Toxicology and applied pharmacology 20031015 |
| Multidrug-resistant tumor cells remain sensitive to a recombinant interleukin-4-Pseudomonas exotoxin, except when overexpressing the multidrug resistance protein MRP1. | Clinical cancer research : an official journal of the American Association for Cancer Research 20031015 |
| Down-regulation of glutathione and Bcl-2 synthesis in mouse B16 melanoma cells avoids their survival during interaction with the vascular endothelium. | The Journal of biological chemistry 20031010 |
| Gene knockdown of gamma-glutamylcysteine synthetase by RNAi in the parasitic protozoa Trypanosoma brucei demonstrates that it is an essential enzyme. | The Journal of biological chemistry 20031010 |
| Mitochondrial glutathione content determines the rate of liver regeneration after partial hepatectomy in eu- and hypothyroid rats. | Journal of hepatology 20031001 |
| Inhibition of CDK5 is protective in necrotic and apoptotic paradigms of neuronal cell death and prevents mitochondrial dysfunction. | Molecular and cellular neurosciences 20031001 |
| Prooxidant effects of NGF withdrawal and MEK inhibition in sympathetic neurons. | Antioxidants & redox signaling 20031001 |
| N-(4-Hydroxyphenyl)retinamide (4-HPR) induces leukemia cell death via generation of reactive oxygen species. | International journal of hematology 20031001 |
| Rapid stimulation of free glucuronate formation by non-glucuronidable xenobiotics in isolated rat hepatocytes. | The Journal of biological chemistry 20030919 |
| Glutathione synthesis during in vitro maturation of buffalo (Bubalus bubalis) oocytes: effects of cysteamine on embryo development. | Theriogenology 20030915 |
| A crucial role for thiol antioxidants in estrogen-deficiency bone loss. | The Journal of clinical investigation 20030915 |
| Oxidative stimuli affect polyglutamine aggregation and cell death in human mutant ataxin-1-expressing cells. | Neuroscience letters 20030904 |
| Repeated inhalation exposures to the bioactivated cytotoxicant naphthalene (NA) produce airway-specific Clara cell tolerance in mice. | Toxicological sciences : an official journal of the Society of Toxicology 20030901 |
| Role of PKC-delta activity in glutathione-depleted neuroblastoma cells. | Free radical biology & medicine 20030901 |
| ars1, an Arabidopsis mutant exhibiting increased tolerance to arsenate and increased phosphate uptake. | The Plant journal : for cell and molecular biology 20030901 |
| Cooperative interaction between ascorbate and glutathione during mitochondrial impairment in mesencephalic cultures. | Journal of neurochemistry 20030901 |
| Regulation of glutathione in cardiac myocytes. | Journal of molecular and cellular cardiology 20030901 |
| Transduction of green fluorescent protein increased oxidative stress and enhanced sensitivity to cytotoxic drugs in neuroblastoma cell lines. | Molecular cancer therapeutics 20030901 |
| Induction of glia maturation factor-beta in proximal tubular cells leads to vulnerability to oxidative injury through the p38 pathway and changes in antioxidant enzyme activities. | The Journal of biological chemistry 20030829 |
| Inhibition of liver trans-sulphuration pathway by propargylglycine mimics gene expression changes found in the mammary gland of weaned lactating rats: role of glutathione. | The Biochemical journal 20030801 |
| Differential role of glutaredoxin and thioredoxin in metabolic oxidative stress-induced activation of apoptosis signal-regulating kinase 1. | The Biochemical journal 20030801 |
| Glutathione depletion exacerbates methylenedianiline toxicity to biliary epithelial cells and hepatocytes in rats. | Toxicological sciences : an official journal of the Society of Toxicology 20030801 |
| Modulation of benzo[a]pyrene-induced p53 DNA activity by acrolein. | Carcinogenesis 20030801 |
| The selection between apoptosis and necrosis is differentially regulated in hydrogen peroxide-treated and glutathione-depleted human promonocytic cells. | Cell death and differentiation 20030801 |
| Requirement of intracellular free thiols for hydrogen peroxide-induced hypertrophy in cardiomyocytes. | Journal of cellular biochemistry 20030801 |
| Effect of glutathione depletion and hydrophilic bile acids on hepatic acute phase reaction in rats with extrahepatic cholestasis. | Scandinavian journal of gastroenterology 20030801 |
| Covalent binding to glutathione of the DNA-alkylating antitumor agent, S23906-1. | European journal of biochemistry 20030701 |
| Role of PPAR-gamma ligands in neuroprotection against glutamate-induced cytotoxicity in retinal ganglion cells. | Investigative ophthalmology & visual science 20030701 |
| Cigarette smoke extract induces oxidative stress and apoptosis in human lung fibroblasts. | American journal of physiology. Lung cellular and molecular physiology 20030601 |
| Induction of hepatic heme oxygenase-1 by diclofenac in rodents: role of oxidative stress and cytochrome P-450 activity. | Journal of hepatology 20030601 |
| Proteasome inhibition potentiates CYP2E1-mediated toxicity in HepG2 cells. | Hepatology (Baltimore, Md.) 20030601 |
| [Redox-dependent changes in structure and function of hHSF1]. | Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica 20030601 |
| Difference in uptake and toxicity of trivalent and pentavalent inorganic arsenic in rat heart microvessel endothelial cells. | Archives of toxicology 20030601 |
| Relationship between gluconeogenesis and glutathione redox state in rabbit kidney-cortex tubules. | Metabolism: clinical and experimental 20030601 |
| Regulation of the gene encoding glutathione synthetase from the fission yeast. | Journal of biochemistry and molecular biology 20030531 |
| Cisplatin-induced genotoxic effects and endogenous glutathione levels in mice bearing ascites Dalton's lymphoma. | Mutation research 20030515 |
| Glutathione depletion increases nitric oxide-induced oxidative stress in primary rat hepatocyte cultures: involvement of low-molecular-weight iron. | Free radical biology & medicine 20030515 |
| The role of thiol reduction in hydroquinone-induced apoptosis in HEK293 cells. | Chemico-biological interactions 20030506 |
| Chloroform, carbon tetrachloride and glutathione depletion induce secondary genotoxicity in liver cells via oxidative stress. | Toxicology 20030503 |
| Thioredoxin peroxidases can foster cytoprotection or cell death in response to different stressors: over- and under-expression of thioredoxin peroxidase in Drosophila cells. | The Biochemical journal 20030501 |
| Inactivation of deoxycytidine kinase and overexpression of P-glycoprotein in AraC and daunorubicin double resistant leukemic cell lines. | Leukemia research 20030501 |
| Vitamin C metabolomic mapping in the lens with 6-deoxy-6-fluoro-ascorbic acid and high-resolution 19F-NMR spectroscopy. | Investigative ophthalmology & visual science 20030501 |
| Neurotrophic factor effects on oxidative stress-induced neuronal death. | Neurochemical research 20030501 |
| Effect of losartan on oxidative stress-induced hypertension in Sprague-Dawley rats. | American journal of hypertension 20030501 |
| Glutathione depletion overcomes resistance to arsenic trioxide in arsenic-resistant cell lines. | Leukemia 20030501 |
| Effect of prooxidant agents added at the morula/blastocyst stage on bovine embryo development, cell death and glutathione content. | Zygote (Cambridge, England) 20030501 |
| Influence of changes in glutathione concentration on body temperature and tolerance to cerebral ischemia. | Biochemistry. Biokhimiia 20030501 |
| Synthesis and antifilarial evaluation of N1,Nn- xylofuranosylated diaminoalkanes. | Bioorganic & medicinal chemistry 20030417 |
| Reactive oxygen species-mediated regulation of eNOS and iNOS expression in multicellular prostate tumor spheroids. | International journal of cancer 20030410 |
| Hepatic glutathione and nitric oxide are critical for hepatic insulin-sensitizing substance action. | American journal of physiology. Gastrointestinal and liver physiology 20030401 |
| Radiation response of cells during altered protein thiol redox. | Radiation research 20030401 |
| Antagonism of buthionine sulfoximine cytotoxicity for human neuroblastoma cell lines by hypoxia is reversed by the bioreductive agent tirapazamine. | Cancer research 20030401 |
| Maturation-dependent thiol loss increases chondrocyte susceptibility to apoptosis. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20030401 |
| Neuroprotective effects of alpha-tocopherol on oxidative stress in rat striatal cultures. | European journal of pharmacology 20030328 |
| Neurotoxicity from glutathione depletion is dependent on extracellular trace copper. | Journal of neuroscience research 20030315 |
| Glutathione depletion-induced apoptosis of Ha-ras-transformed NIH3T3 cells can be prevented by melatonin. | Oncogene 20030306 |
| The up-regulation of cyclooxygenase-2 expression in human buccal mucosal fibroblasts by arecoline: a possible role in the pathogenesis of oral submucous fibrosis. | Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20030301 |
| Autoxidation of extracellular hydroquinones is a causative event for the cytotoxicity of menadione and DMNQ in A549-S cells. | Archives of biochemistry and biophysics 20030301 |
| Vitamin C and vitamin E restore the resistance of GSH-depleted lens cells to H2O2. | Free radical biology & medicine 20030301 |
| Sulfate conjugating and transport functions of MDCK distal tubular cells. | Kidney international 20030301 |
| Synergy between sulforaphane and selenium in the induction of thioredoxin reductase 1 requires both transcriptional and translational modulation. | Carcinogenesis 20030301 |
| Oxidative modulation of the glutathione-redox couple enhances lipopolysaccharide-induced interleukin 12 P40 production by a mouse macrophage cell line, J774A.1. | Free radical research 20030301 |
| Metallothionein 2A induction by zinc protects HEPG2 cells against CYP2E1-dependent toxicity. | Free radical biology & medicine 20030215 |
| Capacity of adult and prepubertal mouse oocytes to undergo embryo development in the presence of cysteamine. | Molecular reproduction and development 20030201 |
| Glutamine deprivation facilitates tumour necrosis factor induced bacterial translocation in Caco-2 cells by depletion of enterocyte fuel substrate. | Gut 20030201 |
| Enhancement of diethylstilbestrol induced cytotoxicity by bcl-2 antisense oligodeoxynucleotides and a glutathione depletor for prostate cancer. | The Journal of urology 20030201 |
| Induction of c-fos expression by nicotine in human periodontal ligament fibroblasts is related to cellular thiol levels. | Journal of periodontal research 20030201 |
| Level of haem oxygenase does not obligatorily reflect the sensitivity of PC12 cells to an oxidative shock induced by glutathione depletion. | Journal of neurochemistry 20030201 |
| Cytosolic and mitochondrial glutathione in microglial cells are differentially affected by oxidative/nitrosative stress. | Nitric oxide : biology and chemistry 20030201 |
| The role of oxidative stress on the effect of 1,4,7,10,13,16-hexathiacyclooctadecane on copper and zinc toxicity in HepG2 cells. | Human & experimental toxicology 20030201 |
| Fructose-1,6-bisphosphate preserves intracellular glutathione and protects cortical neurons against oxidative stress. | Brain research 20030117 |
| gamma-Glutamylcysteine synthetase in lung cancer. Effect on cell viability. | Methods in molecular medicine 20030101 |
| Evaluation of fluorescent dyes for measuring intracellular glutathione content in primary cultures of human neurons and neuroblastoma SH-SY5Y. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20030101 |
| Retroviral transfer of MRP1 and gamma-glutamyl cysteine synthetase modulates cell sensitivity to L-buthionine-S,R-sulphoximine (BSO): new rationale for the use of BSO in cancer therapy. | European journal of cancer (Oxford, England : 1990) 20030101 |
| [Effect of agents changing the intracellular level of reactive oxygen species on the cell cycle phase distribution in 3T3 and 3T3SV40 cell lines]. | Tsitologiia 20030101 |
| Mediation of cadmium-induced oxidative damage and glucose-6-phosphate dehydrogenase expression through glutathione depletion. | Journal of biochemical and molecular toxicology 20030101 |
| The role of chemically induced glutathione and glutathione S-transferase in protecting against 4-hydroxy-2-nonenal-mediated cytotoxicity in vascular smooth muscle cells. | Cardiovascular toxicology 20030101 |
| Photodynamic therapy with photofrin in combination with Buthionine Sulfoximine (BSO) of human glioma in the nude rat. | Lasers in medical science 20030101 |
| Glutathione depletion or radiation treatment alters respiration and induces apoptosis in R3230Ac mammary carcinoma. | Advances in experimental medicine and biology 20030101 |
| [The correlation of tolerance to cerebral ischemia and body temperature with glutathione concentration]. | Biomeditsinskaia khimiia 20030101 |
| Mechanism of 5-fluorouracil required resistance in human hepatocellular carcinoma cell line Bel(7402). | World journal of gastroenterology 20021215 |
| New model of glutathione deficit during development: Effect on lipid peroxidation in the rat brain. | Journal of neuroscience research 20021215 |
| Role of antioxidants in the O-hydroxyethyl-D-(Ser)8-cyclosporine A (SDZ IMM125)-induced apoptosis in rat hepatocytes. | Biochemical pharmacology 20021215 |
| Superoxide anions mediate veratridine-induced cytochrome c release and caspase activity in bovine chromaffin cells. | British journal of pharmacology 20021201 |
| Control of demand-driven biosynthesis of glutathione in green Arabidopsis suspension culture cells. | Plant physiology 20021201 |
| 2,3,7,8-tetrachlorobenzo-p-dioxin inhibits proliferation of SK-N-SH human neuronal cells through decreased production of reactive oxygen species. | Free radical research 20021201 |
| Enhancement of lipid peroxidation and of the antitumor effect of hyperthermia upon combination with oral eicosapentaenoic acid. | Cancer letters 20021128 |
| Electrophile response element-mediated induction of the cystine/glutamate exchange transporter gene expression. | The Journal of biological chemistry 20021122 |
| Acute inhibition of glutathione biosynthesis alters endothelial function and blood pressure in rats. | European journal of pharmacology 20021115 |
| Synthetic ceramides induce growth arrest or apoptosis by altering cellular redox status. | Archives of biochemistry and biophysics 20021101 |
| Development of an in vitro chemo-radiation response assay for cervical carcinoma. | Gynecologic oncology 20021101 |
| A role for the myoglobin redox cycle in the induction of endothelial cell apoptosis. | Free radical biology & medicine 20021015 |
| Buthionine sulfoximine embryotoxicity is associated with prolonged AP-1 activation. | Teratology 20021001 |
| Pre-treatment with R-lipoic acid alleviates the effects of GSH depletion in PC12 cells: implications for Parkinson's disease therapy. | Neurotoxicology 20021001 |
| Inhibition of glutathione-related enzymes augments LPS-mediated cytokine biosynthesis: involvement of an IkappaB/NF-kappaB-sensitive pathway in the alveolar epithelium. | International immunopharmacology 20021001 |
| Phosphine-induced oxidative damage in rats: role of glutathione. | Toxicology 20020930 |
| Roles of endogenous glutathione levels on 6-hydroxydopamine-induced apoptotic neuronal cell death in human neuroblastoma SK-N-SH cells. | Neuropharmacology 20020901 |
| Altered patterns of phosphorylation in cultured mouse lenses during development of buthionine sulfoximine cataracts. | Experimental eye research 20020901 |
| Proapoptotic and redox state-related signaling of reactive oxygen species generated by transformed fibroblasts. | Oncogene 20020829 |
| Aminopeptidase inhibitors bestatin and actinonin inhibit cell proliferation of myeloma cells predominantly by intracellular interactions. | Cancer letters 20020828 |
| Glutathione levels and BAX activation during apoptosis due to oxidative stress in cells expressing wild-type and mutant cystic fibrosis transmembrane conductance regulator. | The Journal of biological chemistry 20020802 |
| Glutathione depletion enforces the mitochondrial permeability transition and causes cell death in Bcl-2 overexpressing HL60 cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20020801 |
| Redox signaling of cardiac HSF1 DNA binding. | American journal of physiology. Cell physiology 20020801 |
| Glutathione prevents inhibition of fibroblast-mediated collagen gel contraction by cigarette smoke. | American journal of physiology. Lung cellular and molecular physiology 20020801 |
| Cytotoxicity of arsenic trioxide to transitional carcinoma cells. | Urology 20020801 |
| Effect of palm oil on oxidative stress-induced hypertension in Sprague-Dawley rats. | American journal of hypertension 20020801 |
| A novel model of acetaminophen-induced acute hepatic failure in rabbits. | The Journal of surgical research 20020801 |
| Glutathione depletion with L-buthionine-(S,R)-sulfoximine demonstrates deleterious effects in acute pancreatitis of the rat. | Digestive diseases and sciences 20020801 |
| Contribution of glutathione and metallothioneins to protection against copper toxicity and redox cycling: quantitative analysis using MT+/+ and MT-/- mouse lung fibroblast cells. | Chemical research in toxicology 20020801 |
| Synergistic cytotoxicity of buthionine sulfoximine (BSO) and intensive melphalan (L-PAM) for neuroblastoma cell lines established at relapse after myeloablative therapy. | Bone marrow transplantation 20020801 |
| The effect of modulation of glutathione cellular content on busulphan-induced cytotoxicity on hematopoietic cells in vitro and in vivo. | Bone marrow transplantation 20020801 |
| Mechanisms of cytotoxicity of nicotine in human periodontal ligament fibroblast cultures in vitro. | Journal of periodontal research 20020801 |
| Composition of seed storage proteins changed by glutathione treatment of soybeans. | Bioscience, biotechnology, and biochemistry 20020801 |
| Neuroprotective effect of intermittent hypoxia on iron-induced oxidative injury in rat brain. | Experimental neurology 20020801 |
| Apoptosis of oligodendrocytes in secondary cultures from neonatal rat brains. | Neuroscience letters 20020719 |
| Increased macrophage glutathione content reduces cell-mediated oxidation of LDL and atherosclerosis in apolipoprotein E-deficient mice. | Atherosclerosis 20020701 |
| CD95/CD95 ligand-independent potentiation of treosulfan cytotoxicity by BSO in malignant glioma cells in vitro and in vivo. | International journal of oncology 20020701 |
| Blockade of P-selectin does not affect reperfusion injury in hamsters subjected to glutathione inhibition. | Microvascular research 20020701 |
| Antioxidant and pro-oxidant effects of a manganese porphyrin complex against CYP2E1-dependent toxicity. | Free radical biology & medicine 20020701 |
| Inhibition of glutamine synthetase in a549 cells during hyperoxia. | American journal of respiratory cell and molecular biology 20020701 |
| Overexpression of gamma-glutamylcysteine synthetase in human malignant mesothelioma. | Human pathology 20020701 |
| Recognition of a cysteine substrate by E. coli gamma-glutamylcysteine synthetase probed by sulfoximine-based transition-state analogue inhibitors. | Bioscience, biotechnology, and biochemistry 20020701 |
| Interleukin-6 protects PC12 cells from 4-hydroxynonenal-induced cytotoxicity by increasing intracellular glutathione levels. | Free radical biology & medicine 20020615 |
| Thiourea toxicity in mouse C3H/10T1/2 cells expressing human flavin-dependent monooxygenase 3. | Biochemical pharmacology 20020601 |
| Modulation of the multidrug resistance of glioma by glutathione levels depletion--interaction with Tc-99M-Sestamibi and Tc-99M-Tetrofosmin. | Cancer biotherapy & radiopharmaceuticals 20020601 |
| alpha-tocopherol increases the intracellular glutathione level in HaCaT keratinocytes. | Free radical research 20020601 |
| Glutathione depletion in nigrostriatal slice cultures: GABA loss, dopamine resistance and protection by the tetrahydrobiopterin precursor sepiapterin. | Brain research 20020510 |
| Determination of glutamate-cysteine ligase (gamma-glutamylcysteine synthetase) activity by high-performance liquid chromatography and electrochemical detection. | Analytical biochemistry 20020501 |
| Cellular glutathione content, in vitro chemoresponse, and the effect of BSO modulation in samples derived from patients with advanced ovarian cancer. | Gynecologic oncology 20020501 |
| Increasing the DNA damage threshold in breast cancer cells. | Toxicology and applied pharmacology 20020501 |
| Dexamethasone-resistant human Pre-B leukemia 697 cell line evolving elevation of intracellular glutathione level: an additional resistance mechanism. | Japanese journal of cancer research : Gann 20020501 |
| Protection against 3,4-methylenedioxymethamphetamine-induced neurodegeneration produced by glutathione depletion in rats is mediated by attenuation of hyperthermia. | Journal of neurochemistry 20020501 |
| Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
| Roles of oxidative stress and glutathione depletion in JP-8 jet fuel-induced apoptosis in rat lung epithelial cells. | Toxicology and applied pharmacology 20020415 |
| Impairment of mineralocorticoid receptor (MR)-dependent biological response by oxidative stress and aging: correlation with post-translational modification of MR and decreased ADP-ribosylatable level of elongating factor 2 in kidney cells. | The Journal of biological chemistry 20020405 |
| The influence of P-glycoprotein on morphine transport in Caco-2 cells. Comparison with paclitaxel. | European journal of pharmacology 20020405 |
| Hepatic xenobiotic metabolism of cylindrospermopsin in vivo in the mouse. | Toxicon : official journal of the International Society on Toxinology 20020401 |
| Adenovirus-mediated overexpression of catalase in the cytosolic or mitochondrial compartment protects against toxicity caused by glutathione depletion in HepG2 cells expressing CYP2E1. | The Journal of pharmacology and experimental therapeutics 20020401 |
| Exogenous cysteine and cystine promote cell proliferation in CaCo-2 cells. | Cell proliferation 20020401 |
| The contribution of 2,3,5-trichlorophenyl methyl sulfone, a metabolite of 1,2,4-trichlorobenzene, to the delta-aminolevulinic acid synthetase induction by 1,2,4-trichlorobenzene in rat liver. | Chemosphere 20020401 |
| Role of glutathione in metabolic degradation of dichloromethane in rats. | Toxicology letters 20020324 |
| Effect of glutathione synthesis stimulation during in vitro maturation of ovine oocytes on embryo development and intracellular peroxide content. | Theriogenology 20020315 |
| Arsenic trioxide-induced apoptosis and its enhancement by buthionine sulfoximine in hepatocellular carcinoma cell lines. | Biochemical and biophysical research communications 20020308 |
| Involvement of p38 mitogen-activated protein kinase in PLL-AGE-induced cyclooxgenase-2 expression. | European journal of pharmacology 20020308 |
| Redox regulation of TNF-alpha biosynthesis: augmentation by irreversible inhibition of gamma-glutamylcysteine synthetase and the involvement of an IkappaB-alpha/NF-kappaB-independent pathway in alveolar epithelial cells. | Cellular signalling 20020301 |
| Elevation of glutathione induced by low-dose gamma rays and its involvement in increased natural killer activity. | Radiation research 20020301 |
| Role of glutathione depletion and reactive oxygen species generation in apoptotic signaling in a human B lymphoma cell line. | Cell death and differentiation 20020301 |
| Nitric oxide synthase expression in hypertension induced by inhibition of glutathione synthase. | The Journal of pharmacology and experimental therapeutics 20020301 |
| Role of gamma-glutamyltranspeptidase on the response of poorly and moderately differentiated rhabdomyosarcoma cell lines to buthionine sulfoximine-induced inhibition of glutathione synthesis. | Anti-cancer drugs 20020301 |
| Arsenic trioxide as a novel anticancer agent against human transitional carcinoma--characterizing its apoptotic pathway. | Anti-cancer drugs 20020301 |
| Modulation of DNA single-strand breaks by intracellular glutathione in human lung cells exposed to asbestos fibers. | Mutation research 20020215 |
| Acrylamide-induced cellular transformation. | Toxicological sciences : an official journal of the Society of Toxicology 20020201 |
| Inhibition of cell proliferation and AP-1 activity by acrolein in human A549 lung adenocarcinoma cells due to thiol imbalance and covalent modifications. | Chemical research in toxicology 20020201 |
| Anti-cancer action of 4-iodo-3-nitrobenzamide in combination with buthionine sulfoximine: inactivation of poly(ADP-ribose) polymerase and tumor glycolysis and the appearance of a poly(ADP-ribose) polymerase protease. | Biochemical pharmacology 20020201 |
| Influence of antioxidant depletion on nitrergic relaxation in the pig gastric fundus. | British journal of pharmacology 20020201 |
| Redox signaling-mediated regulation of lipopolysaccharide-induced proinflammatory cytokine biosynthesis in alveolar epithelial cells. | Antioxidants & redox signaling 20020201 |
| Fructose inhibits apoptosis induced by reoxygenation in rat hepatocytes by decreasing reactive oxygen species via stabilization of the glutathione pool. | Biochimica et biophysica acta 20020130 |
| Prior induction of heme oxygenase-1 with glutathione depletor ameliorates the renal ischemia and reperfusion injury in the rat. | FEBS letters 20020116 |
| Antiproliferative and cytotoxic effect of a novel organotin compound on mammalian cells both in vitro and in vivo. | Mutation research 20020115 |
| Activation of transcription factors by drugs inducing oxidative stress in rat liver. | Biochemical pharmacology 20020115 |
| The involvement of L-gamma-glutamyl-L-cysteinyl-glycine (glutathione/GSH) in the mechanism of redox signaling mediating MAPK(p38)-dependent regulation of pro-inflammatory cytokine production. | Biochemical pharmacology 20020115 |
| Drosophila melanogaster glutamate-cysteine ligase activity is regulated by a modifier subunit with a mechanism of action similar to that of the mammalian form. | The Journal of biological chemistry 20020111 |
| Escherichia coli gamma-glutamylcysteine synthetase. Two active site metal ions affect substrate and inhibitor binding. | The Journal of biological chemistry 20020104 |
| Glutathione might exert an important function in caerulein-stimulated amylase release in isolated rat pancreatic acini. | Pancreas 20020101 |
| Toxicity by pyruvate in HepG2 cells depleted of glutathione: role of mitochondria. | Free radical biology & medicine 20020101 |
| Noninvasive imaging of tumor redox status and its modification by tissue glutathione levels. | Cancer research 20020101 |
| gamma-Glutamyl transpeptidase overexpression increases metastatic growth of B16 melanoma cells in the mouse liver. | Hepatology (Baltimore, Md.) 20020101 |
| Cystathionine pathway-dependent cytotoxicities of diethyl maleate and diamide in rat and human hepatoma-derived cell cultures. | Alternatives to laboratory animals : ATLA 20020101 |
| Cytotoxicity of amino alcohols to rat hepatoma-derived Fa32 cells. | Alternatives to laboratory animals : ATLA 20020101 |
| Arsenic induces oxidative DNA damage in mammalian cells. | Molecular and cellular biochemistry 20020101 |
| Lipopolysaccharide prevents cell death caused by glutathione depletion: possible mechanisms of protection. | Neuroscience 20020101 |
| Arsenic induces oxidative stress and activates stress gene expressions in cultured lung epithelial cells. | Journal of cellular biochemistry 20020101 |
| Disulfiram induces apoptosis in human melanoma cells: a redox-related process. | Molecular cancer therapeutics 20020101 |
| The glutathione system in alkylator resistance. | Cancer treatment and research 20020101 |
| Efficacy of a whey protein concentrate on the inhibition of stomach ulcerative lesions caused by ethanol ingestion. | Journal of medicinal food 20020101 |
| Induction of vascular endothelial growth factor expression and hypoxia-inducible factor 1alpha protein by the oxidative stressor arsenite. | The Journal of biological chemistry 20011221 |
| Altered differentiation in rat and rabbit limb bud micromass cultures by glutathione modulating agents. | Free radical biology & medicine 20011215 |
| Effect of glutathione depletion on antitumor drug toxicity (apoptosis and necrosis) in U-937 human promonocytic cells. The role of intracellular oxidation. | The Journal of biological chemistry 20011214 |
| Redox cycling of diaspirin cross-linked hemoglobin induces G2/M arrest and apoptosis in cultured endothelial cells. | Blood 20011201 |
| Ceramide-mediated apoptosis in lung epithelial cells is regulated by glutathione. | American journal of respiratory cell and molecular biology 20011201 |
| Quantitative imaging of glutathione in hippocampal neurons and glia in culture using monochlorobimane. | Journal of neuroscience research 20011201 |
| Glutathione depletion switches nitric oxide neurotrophic effects to cell death in midbrain cultures: implications for Parkinson's disease. | Journal of neurochemistry 20011201 |
| GSH is required to recycle ascorbic acid in cultured liver cell lines. | Antioxidants & redox signaling 20011201 |
| Activation or detoxification of mutagenic and carcinogenic compounds in transgenic Drosophila expressing human glutathione S-transferase. | Mutation research 20011115 |
| Restoration of glutathione levels in vascular smooth muscle cells exposed to high glucose conditions. | Free radical biology & medicine 20011115 |
| Unique action determinants of double acting topoisomerase inhibitor, TAS-103. | International journal of oncology 20011101 |
| Therapeutic efficacy of aortic administration of N-acetylcysteine as a chemoprotectant against bone marrow toxicity after intracarotid administration of alkylators, with or without glutathione depletion in a rat model. | Cancer research 20011101 |
| Long-term smoking causes nitroglycerin resistance in platelets by depletion of intraplatelet glutathione. | Arteriosclerosis, thrombosis, and vascular biology 20011101 |
| Increasing the glutathione content in a chilling-sensitive maize genotype using safeners increased protection against chilling-induced injury. | Plant physiology 20011101 |
| Role of reactive oxygen species and glutathione in inorganic mercury-induced injury in human glioma cells. | Neurochemical research 20011101 |
| Buthionine sulfoximine and myeloablative concentrations of melphalan overcome resistance in a melphalan-resistant neuroblastoma cell line. | Journal of pediatric hematology/oncology 20011101 |
| Dual role of glutathione in modulating camptothecin activity: depletion potentiates activity, but conjugation enhances the stability of the topoisomerase I-DNA cleavage complex. | Molecular cancer therapeutics 20011101 |
| TNFalpha-induced glutathione depletion lies downstream of cPLA(2) in L929 cells. | FEBS letters 20011026 |
| Cold-induced apoptosis in isolated rat hepatocytes: protective role of glutathione. | Free radical biology & medicine 20011015 |
| Hydrogen peroxide detoxification in the midgut of the blood-sucking insect, Rhodnius prolixus. | Archives of insect biochemistry and physiology 20011001 |
| Induction of mild intracellular redox imbalance inhibits proliferation of CaCo-2 cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011001 |
| Effect of advanced glycation end products on oxidative stress in endothelial cells in culture: a warning on the use of cells studied in serum-free media. | Diabetologia 20011001 |
| Endothelium-dependent vasorelaxation in inhibited by in vivo depletion of vascular thiol levels: role of endothelial nitric oxide synthase. | Free radical research 20011001 |
| Enhanced sensitivity of insulin-resistant adipocytes to vanadate is associated with oxidative stress and decreased reduction of vanadate (+5) to vanadyl (+4). | The Journal of biological chemistry 20010921 |
| Enhancement of the activity of doxorubicin by inhibition of glutamate transporter. | Toxicology letters 20010915 |
| Glutathione peroxidase-1 overexpression prevents ceramide production and partially inhibits apoptosis in doxorubicin-treated human breast carcinoma cells. | Molecular pharmacology 20010901 |
| [Oxidative metabolism of HIV-infected macrophages: the role of glutathione and a pharmacologic approach]. | Pathologie-biologie 20010901 |
| Glutathione depletion restores the susceptibility of cisplatin-resistant chronic myelogenous leukemia cell lines to Natural Killer cell-mediated cell death via necrosis rather than apoptosis. | European journal of cell biology 20010901 |
| Contrasting effects of thiol-modulating agents on endothelial NO bioactivity. | American journal of physiology. Cell physiology 20010801 |
| L-DOPA and glia-conditioned medium have additive effects on tyrosine hydroxylase expression in human catecholamine-rich neuroblastoma NB69 cells. | Journal of neurochemistry 20010801 |
| In vitro toxicity assessment of a new series of high energy compounds. | The Science of the total environment 20010702 |
| Differential effects of buthionine sulphoximine in hypoxic and non-hypoxic regions of human cervical carcinoma xenografts. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20010701 |
| Effects of cellular redox balance on induction of apoptosis by eicosapentaenoic acid in HT29 colorectal adenocarcinoma cells and rat colon in vivo. | Gut 20010701 |
| Resolution, detection, and characterization of redox conformers of human HSF1. | The Journal of biological chemistry 20010629 |
| Thiram-induced cytotoxicity is accompanied by a rapid and drastic oxidation of reduced glutathione with consecutive lipid peroxidation and cell death. | Toxicology 20010621 |
| The role of glutathione in the toxicity of smoke condensates from cigarettes that burn or heat tobacco. | Free radical biology & medicine 20010615 |
| Reduced glutathione protect cells from ouabain toxicity. | Biochimica et biophysica acta 20010615 |
| Astrocytes protect neurons from nitric oxide toxicity by a glutathione-dependent mechanism. | Journal of neurochemistry 20010601 |
| DL-Buthionine-S,R-sulfoximine affects intestinal alkaline phosphatase activity. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20010601 |
| Assessment of DNA damage in C6 glioma cells after antidepressant treatment using an alkaline comet assay. | Archives of toxicology 20010601 |
| Down-regulation of intrinsic P-glycoprotein expression in multicellular prostate tumor spheroids by reactive oxygen species. | The Journal of biological chemistry 20010518 |
| Cysteine regulates expression of cysteine dioxygenase and gamma-glutamylcysteine synthetase in cultured rat hepatocytes. | American journal of physiology. Endocrinology and metabolism 20010501 |
| How protein kinase C activation protects nerve cells from oxidative stress-induced cell death. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20010501 |
| Cytotoxicity of reactive oxygen species and related agents toward undifferentiated and differentiated rat phenochromocytoma PC12 cells. | Biological & pharmaceutical bulletin 20010501 |
| Association of glutathione with flowering in Arabidopsis thaliana. | Plant & cell physiology 20010501 |
| Glutathione deficiency intensifies ischaemia-reperfusion induced cardiac dysfunction and oxidative stress. | Acta physiologica Scandinavica 20010501 |
| [Mechanisms of arsenic trioxide-induced apoptosis in myeloma cells]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20010501 |
| Modulation of cisplatin cytotoxicity and cisplatin-induced DNA cross-links in HepG2 cells by regulation of glutathione-related mechanisms. | Molecular pharmacology 20010401 |
| Regulation of thioltransferase expression in human lens epithelial cells. | Investigative ophthalmology & visual science 20010401 |
| Programmed cell death induced by glutathione depletion in PC 12 cells is blocked by inhibitors of 12 lipoxygenase, but does not appear to be mediated through the formation of 12 HETE derivatives. | Free radical biology & medicine 20010401 |
| Endogenous glutathione and platelet function in platelet concentrates stored in plasma or platelet additive solution. | Transfusion medicine (Oxford, England) 20010401 |
| Diesel exhaust particle-induced cell death of human leukemic promyelocytic cells HL-60 and their variant cells HL-NR6. | Biological & pharmaceutical bulletin 20010401 |
| Astrocytes as a predominant cellular site of (99m)Tc-HMPAO retention. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20010401 |
| Removal of glutathione produces apoptosis and necrosis in HepG2 cells overexpressing CYP2E1. | Alcoholism, clinical and experimental research 20010401 |
| The role of intracellular oxidation in death induction (apoptosis and necrosis) in human promonocytic cells treated with stress inducers (cadmium, heat, X-rays). | European journal of cell biology 20010401 |
| Astrocytes overexpressing Cu,Zn superoxide dismutase have increased resistance to oxidative injury. | Glia 20010315 |
| Peptide transport by the multidrug resistance protein MRP1. | Cancer research 20010315 |
| Rescue from enhanced alkylator-induced cell death with low molecular weight sulfur-containing chemoprotectants. | The Journal of pharmacology and experimental therapeutics 20010301 |
| Oxidative stress and induction of heme oxygenase-1 in the kidney in sickle cell disease. | The American journal of pathology 20010301 |
| Depletion of glutathione up-regulates mitochondrial complex I expression in glial cells. | Journal of neurochemistry 20010301 |
| Sequence-selective DNA binding drugs mithramycin A and chromomycin A3 are potent inhibitors of neuronal apoptosis induced by oxidative stress and DNA damage in cortical neurons. | Annals of neurology 20010301 |
| Glutathione content is correlated with the sensitivity of lines of PC12 cells to cisplatin without a corresponding change in the accumulation of platinum. | Molecular and cellular biochemistry 20010301 |
| The role of glutathione in the neurotoxicity of artemisinin derivatives in vitro. | Biochemical pharmacology 20010215 |
| Vitamin D is a prooxidant in breast cancer cells. | Cancer research 20010215 |
| GSH role on platelet-derived growth factor receptor tyrosine phosphorylation induced by H2O2. | Biochemical and biophysical research communications 20010209 |
| Modulation of the stress response during apoptosis and necrosis induction in cadmium-treated U-937 human promonocytic cells. | Biochimica et biophysica acta 20010205 |
| L-buthionine sulfoximine potentiates the antitumor effect of 4-hydroperoxycyclophosphamide when administered locally in a rat glioma model. | Neurosurgery 20010201 |
| Mechanism and significance of increased glutathione level in human hepatocellular carcinoma and liver regeneration. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010101 |
| Intracellular glutathione regulates tumour necrosis factor-alpha-induced p38 MAP kinase activation and RANTES production by human bronchial epithelial cells. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20010101 |
| p-Aminophenol-induced liver toxicity: tentative evidence of a role for acetaminophen. | Journal of biochemical and molecular toxicology 20010101 |
| CYP2E1-dependent toxicity and up-regulation of antioxidant genes. | Journal of biomedical science 20010101 |
| NF kappa b signaling in posthypoxic endothelial cells: relevance to E-selectin expression and neutrophil adhesion. | Journal of vascular research 20010101 |
| Reactive oxygen species uncouple external horizontal cells in the carp retina and glutathione couples them again. | Neuroscience 20010101 |
| Simultaneous treatment with 1-beta-D-arabinofuranosylcytosine and daunorubicin induces cross-resistance to both drugs due to a combination-specific mechanism in HL60 cells. | Cancer research 20010101 |
| Decreased oxidant buffering impairs NF-kappaB activation and ICAM-1 transcription in endothelial cells. | Shock (Augusta, Ga.) 20010101 |
| Importance of dose intensity in neuro-oncology clinical trials: summary report of the Sixth Annual Meeting of the Blood-Brain Barrier Disruption Consortium. | Neuro-oncology 20010101 |
| Changes in the levels of glutathione after cellular and cutaneous damage induced by squalene monohydroperoxide. | Journal of biochemical and molecular toxicology 20010101 |
| Dual role of the NF-kappaB transcription factor in the death of immature neurons. | Neuroscience 20010101 |
| Metabolic cooperation of ascorbic acid and glutathione in normal and vitamin C-deficient ODS rats. | Physiological chemistry and physics and medical NMR 20010101 |
| Arsenic trioxide induces multiple myeloma cell apoptosis via disruption of mitochondrial transmembrane potentials and activation of caspase-3. | Chinese medical journal 20010101 |
| L-Buthionine-(S,R)-sulfoximine, an irreversible inhibitor of gamma-glutamylcysteine synthetase, augments LPS-mediated pro-inflammatory cytokine biosynthesis: evidence for the implication of an IkappaB-alpha/NF-kappaB insensitive pathway. | European cytokine network 20010101 |
| Hematotoxicity and blood glutathione levels after cisplatin treatment of tumor-bearing mice. | Cell biology and toxicology 20010101 |
| Increased lipid peroxidation in the liver and kidney and their mitochondrial fractions following buthionine sulfoximine induced glutathione depletion in guinea pigs. | Research communications in molecular pathology and pharmacology 20010101 |
| Antioxidants may contribute in the fight against ageing: an in vitro model. | Mechanisms of ageing and development 20001220 |
| Glutathione depletion induces apoptosis of rat hepatocytes through activation of protein kinase C novel isoforms and dependent increase in AP-1 nuclear binding. | Free radical biology & medicine 20001215 |
| Establishment of a human hepatoma cell line, HLE/2E1, suitable for detection of p450 2E1-related cytotoxicity. | In vitro cellular & developmental biology. Animal 20001001 |
| Inducers of gamma-glutamylcysteine synthetase and their effects on glutathione synthetase expression. | Biochimica et biophysica acta 20000907 |
| [Effect of thiabendazole (TBZ) on glutathione (GSH) and GSH related enzymes in mice liver]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20000901 |
| Neuroprotective effect of cyclic GMP against radical-induced toxicity in cultured spinal motor neurons. | Journal of neuroscience research 20000815 |
| The protective effect of glutathione administration on adriamycin-induced acute cardiac toxicity in rats. | Pharmacological research 20000801 |
| Elevated airway GSH resynthesis confers protection to Clara cells from naphthalene injury in mice made tolerant by repeated exposures. | The Journal of pharmacology and experimental therapeutics 20000801 |
| Hepatocellular response to chemical stress in CD-1 mice: induction of early genes and gamma-glutamylcysteine synthetase. | Hepatology (Baltimore, Md.) 20000801 |
| Induction of oxidative stress by glutathione depletion causes severe hypertension in normal rats. | Hypertension (Dallas, Tex. : 1979) 20000701 |
| Arsenic trioxide-induced apoptosis and differentiation are associated respectively with mitochondrial transmembrane potential collapse and retinoic acid signaling pathways in acute promyelocytic leukemia. | Leukemia 20000201 |
| Simultaneous inhibition of renal phospholipase A(2) and glutathione synthesis by manoalide and DL-buthionine sulfoximine induces acute tubular dysfunction in rats. | Experimental nephrology 20000101 |
| Differential role of ethanol and acetaldehyde in the induction of oxidative stress in HEP G2 cells: effect on transcription factors AP-1 and NF-kappaB. | Hepatology (Baltimore, Md.) 19991201 |
| Arsenic trioxide sensitivity is associated with low level of glutathione in cancer cells. | British journal of cancer 19991101 |
| CYP2E1-mediated oxidative stress induces collagen type I expression in rat hepatic stellate cells. | Hepatology (Baltimore, Md.) 19991001 |
| Stable overexpression of manganese superoxide dismutase in mitochondria identifies hydrogen peroxide as a major oxidant in the AP-1-mediated induction of matrix-degrading metalloprotease-1. | The Journal of biological chemistry 19990903 |
| Glutathione modulates rat and mouse hepatocyte sensitivity to tumor necrosis factor toxicity. | Gastroenterology 19981101 |
| Down-regulation of cytochrome P450 1A1 gene promoter by oxidative stress. Critical contribution of nuclear factor 1. | The Journal of biological chemistry 19981009 |
| Regenerative response in acute renal failure due to vitamin E deficiency and glutathione depletion in rats. | Biochemical pharmacology 19980815 |
| Characterization of antioxidant properties of natural killer-enhancing factor-B and induction of its expression by hydrogen peroxide. | Toxicology and applied pharmacology 19971101 |
| Hepatic fatty acid synthase gene transcription is induced by a dietary copper deficiency. | The American journal of physiology 19970601 |
| Effect of thiols on cadmium-induced expression of metallothionein and other oxidant stress genes in rat lung epithelial cells. | Toxicology 19970516 |
| Inhibition of cell growth and sensitization to oxidative damage by overexpression of manganese superoxide dismutase in rat glioma cells. | Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 19960901 |
| Chromium induces a persistent activation of mitogen-activated protein kinases by a redox-sensitive mechanism in H4 rat hepatoma cells. | Cancer research 19960501 |
| Reversion in Chinese hamster lines amplified at the AMPD2 locus: spontaneous and benzamide-stimulated gradual loss of amplified alleles of marker genes. | Mutation research 19960117 |
| Naphthylisothiocyanate disposition in bile and its relationship to liver glutathione and toxicity. | Biochemical pharmacology 19951026 |
| Differential activation of heat-shock and oxidation-specific stress genes in chemically induced oxidative stress. | The Biochemical journal 19950715 |
| Induction of c-fos and c-jun proto-oncogene expression by asbestos is ameliorated by N-acetyl-L-cysteine in mesothelial cells. | Cancer research 19950515 |
| Mechanism of cross-resistance to cisplatin in a mitomycin C-resistant human bladder cancer cell line. | International journal of cancer 19950504 |
| Regulation of hepatic nitric oxide synthase by reactive oxygen intermediates and glutathione. | Archives of biochemistry and biophysics 19950201 |
| Regulation of [Ah] gene battery enzymes and glutathione levels by 5,10-dihydroindeno[1,2-b]indole in mouse hepatoma cell lines. | Carcinogenesis 19941001 |
| Glutathione precursor and antioxidant activities of N-acetylcysteine and oxothiazolidine carboxylate compared in in vitro studies of HIV replication. | AIDS research and human retroviruses 19940801 |
| p-Dichlorobenzene-induced hepatotoxicity in mice depleted of glutathione by treatment with buthionine sulfoximine. | Toxicology 19940101 |
| Nephrotoxicity and covalent binding of 1,1-dichloroethylene in buthionine sulphoximine-treated mice. | Archives of toxicology 19930101 |
| Possible role of thioformamide as a proximate toxicant in the nephrotoxicity of thiabendazole and related thiazoles in glutathione-depleted mice: structure-toxicity and metabolic studies. | Chemical research in toxicology 19930101 |
| Influence of modulators of epoxide metabolism on the cytotoxicity of trans-anethole in freshly isolated rat hepatocytes. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 19920601 |
| An improved model of acetaminophen-induced fulminant hepatic failure in dogs. | Hepatology (Baltimore, Md.) 19920201 |
| In vivo nephrotoxicity induced in mice by chromium(VI). Involvement of glutathione and chromium(V). | Biological trace element research 19911001 |
| The site specificity and sensitivity of the rat liver to butylated hydroxytoluene-induced damage. | Toxicology and applied pharmacology 19910315 |
| Nephrotoxicity of thiabendazole in mice depleted of glutathione by treatment with DL-buthionine sulphoximine. | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 19900301 |
| 1,2-Dichloropropane (DCP) toxicity is correlated with DCP-induced glutathione (GSH) depletion and is modulated by factors affecting intracellular GSH. | Archives of toxicology 19900101 |
| Enhancement of cisplatin toxicity by buthionine sulfoximine, a glutathione-depleting agent, in mice. | Research communications in chemical pathology and pharmacology 19900101 |
| Injurious effect of buthionine sulfoximine, an inhibitor of glutathione biosynthesis, on the lethality and urotoxicity of cyclophosphamide in mice. | Japanese journal of pharmacology 19890901 |
| Modification of cyclophosphamide-induced urotoxicity by buthionine sulfoximine and disulfiram in mice. | Research communications in chemical pathology and pharmacology 19890801 |
| Influence of buthionine sulfoximine on the lethality of ifosfamide and ifosfamide-induced urotoxicity in mice. | Research communications in chemical pathology and pharmacology 19890301 |
| Radiosensitizing effect of misonidazole in combination with an inhibitor of glutathione synthesis in murine tumors. | International journal of radiation oncology, biology, physics 19860901 |
| Enhancement in the aerobic toxicity of misonidazole and SR-2508 by buthionine sulfoximine and 4-hydroxypyrazole: the role of hydrogen peroxide. | International journal of radiation oncology, biology, physics 19860701 |
| Effects of oxidative stress caused by hyperoxia and diquat. A study in isolated hepatocytes. | Free radical research communications 19860101 |