(3S)-1-Chloro-3-tosylamido-7-amino-2-heptanone HCl
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Leishmania (L.) amazonensis peptidase activities inside the living cells and in their lysates. | Molecular and biochemical parasitology 20120801 |
Cysteine peptidases, secreted by Trichomonas gallinae, are involved in the cytopathogenic effects on a permanent chicken liver cell culture. | PloS one 20120101 |
Synthesis and acrosin inhibitory activities of substituted ethyl 5-(4-aminophenyl)-1H-pyrazole-3-carboxylate derivatives. | Bioorganic & medicinal chemistry letters 20111001 |
Malaria proteases mediate inside-out egress of gametocytes from red blood cells following parasite transmission to the mosquito. | Cellular microbiology 20110601 |
Expression of trypsin-like serine peptidases in pre-imaginal stages of Aedes aegypti (Diptera: Culicidae). | Archives of insect biochemistry and physiology 20110401 |
Collagenolytic activity in sonic extracts of Tannerella forsythia. | Archives of oral biology 20100801 |
Purification, characterization and substrate specificity of a trypsin from the Amazonian fish tambaqui (Colossoma macropomum). | Biochemical and biophysical research communications 20100604 |
Okadaic acid induces DNA fragmentation via caspase-3-dependent and caspase-3-independent pathways in Chinese hamster ovary (CHO)-K1 cells. | The FEBS journal 20100101 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum. | Nature chemical biology 20091001 |
Mechanisms of growth inhibition in human papillomavirus positive and negative cervical cancer cells by the chloromethyl ketone protease inhibitor, succinyl-alanine-alanine-proline-phenylalanine chloromethyl ketone. | The Journal of pharmacology and experimental therapeutics 20090701 |
Synthesis and biological evaluation of reversible inhibitors of IdeS, a bacterial cysteine protease and virulence determinant. | Bioorganic & medicinal chemistry 20090501 |
Porphyromonas gingivalis stimulates TACE production by T cells. | Oral microbiology and immunology 20090401 |
Properties of a Kunitz-type trypsin inhibitor from Delonix regia seeds against digestive proteinases of Anagasta kuehniella (Z.) and Corcyra cephalonica (S.) (Lepidoptera: Pyralidae). | Protein and peptide letters 20090101 |
Serine protease inhibitors N-alpha-tosyl-L-lysinyl-chloromethylketone (TLCK) and N-tosyl-L-phenylalaninyl-chloromethylketone (TPCK) do not inhibit caspase-3 and caspase-7 processing in cells exposed to pro-apoptotic inducing stimuli. | Journal of cellular biochemistry 20081215 |
The role of the RgpA-Kgp proteinase-adhesin complexes in the adherence of Porphyromonas gingivalis to fibroblasts. | Microbiology (Reading, England) 20081001 |
The structural basis of proteolytic activation of bovine glutamate dehydrogenase. | Protein science : a publication of the Protein Society 20080801 |
Fluorescence anisotropy assay for the traceless kinetic analysis of protein digestion. | Analytical chemistry 20080601 |
Serine protease inhibitors N-alpha-tosyl-L-lysinyl-chloromethylketone (TLCK) and N-tosyl-L-phenylalaninyl-chloromethylketone (TPCK) are potent inhibitors of activated caspase proteases. | Journal of cellular biochemistry 20080401 |
Effect of protease inhibitors on exflagellation in Plasmodium falciparum. | Molecular and biochemical parasitology 20080401 |
Two trypsin isoforms from the intestine of the grass carp (Ctenopharyngodon idellus). | Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology 20070801 |
Inhibition of human erythrocyte invasion by Babesia divergens using serine protease inhibitors. | Molecular and biochemical parasitology 20070501 |
Aspartic proteinases in the digestive tract of marine decapod crustaceans. | Journal of experimental zoology. Part A, Comparative experimental biology 20060801 |
Morphology and preliminary enzyme characterization of the salivary glands from the predatory bug Podisus nigrispinus (Heteroptera: Pentatomidae). | Bulletin of entomological research 20060601 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
Characterization of a new platelet aggregating factor from crotoxin Crotalus durissus cascavella venom. | The protein journal 20060401 |
Differentiation and protease production in Micromonospora echinospora (ATCC 15837). | Antonie van Leeuwenhoek 20060101 |
Plasmodium berghei: effect of protease inhibitors during gametogenesis and early zygote development. | Experimental parasitology 20051201 |
Determination of the cytotoxic effect of Clostridium histolyticum culture supernatant on HeLa cells in the presence of protease inhibitors. | FEMS immunology and medical microbiology 20050801 |
Can application of serine protease inhibitors TPCK and TLCK provide evidence for possible involvement of serine protease Omi/HtrA2 in imatinib mesylate-induced cell death of BCR-ABL-positive human leukemia cells? | Leukemia 20050601 |
[Withdrawal of exogenous auxin induces programmed cell death of cotton embryogenic suspension cultures]. | Zhi wu sheng li yu fen zi sheng wu xue xue bao = Journal of plant physiology and molecular biology 20050201 |
Modulation of tryptase release from human tonsil mast cells by protease inhibitors. | Pharmacological reports : PR 20050101 |
N-alpha-p-tosyl-L-lysine chloromethyl ketone (TLCK) suppresses neuritic degeneration caused by different experimental paradigms including in vitro Wallerian degeneration. | Brain research 20041224 |
Modulation of tryptase and histamine release from human lung mast cells by protease inhibitors. | Asian Pacific journal of allergy and immunology 20041201 |
[Effect of tryptase inhibitors on histamine release from human colon mast cells]. | Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology 20041101 |
Do alkylating agents modify the histidine residue of the desensitized butyrylcholinesterase? | The protein journal 20041101 |
A novel 'clip-and-link' activity of repeat in toxin (RTX) proteins from gram-negative pathogens. Covalent protein cross-linking by an Asp-Lys isopeptide bond upon calcium-dependent processing at an Asp-Pro bond. | The Journal of biological chemistry 20040611 |
Proteinase inhibitors TPCK and TLCK prevent Entamoeba histolytica induced disturbance of tight junctions and microvilli in enteric cell layers in vitro. | International journal for parasitology 20040601 |
The 26S proteasome participates in the sequential inhibition of estrous behavior induced by progesterone in rats. | Endocrinology 20040501 |
Trypsin induces epidermal proliferation and inflammation in murine skin. | Experimental dermatology 20040401 |
NF-kappaB-dependent induction of osteoprotegerin by Porphyromonas gingivalis in endothelial cells. | Biochemical and biophysical research communications 20040227 |
Interaction of Porphyromonas gingivalis with low-density lipoproteins: implications for a role for periodontitis in atherosclerosis. | Journal of periodontal research 20040201 |
Indinavir alters sterol and fatty acid homeostatic mechanisms in primary rat hepatocytes by increasing levels of activated sterol regulatory element-binding proteins and decreasing cholesterol 7alpha-hydroxylase mRNA levels. | Biochemical pharmacology 20040115 |
Dual role of NF-kappaB in apoptosis of THP-1 cells during treatment with etoposide and lipopolysaccharide. | Leukemia research 20040101 |
In vitro activation of the hemolysin in Prevotella nigrescens ATCC 33563 and Prevotella intermedia ATCC 25611. | Research in microbiology 20040101 |
Characterization of a trypsin-like serine protease of activated B cells mediating the cleavage of surface proteins. | Biochimica et biophysica acta 20031205 |
Gliadin increases iNOS gene expression in interferon-gamma-stimulated RAW 264.7 cells through a mechanism involving NF-kappa B. | Naunyn-Schmiedeberg's archives of pharmacology 20030701 |
Serine protease inhibitors modulate chemotactic cytokine production by human lung fibroblasts in vitro. | American journal of physiology. Lung cellular and molecular physiology 20030501 |
Purification and characterization of PrbA, a new esterase from Enterobacter cloacae hydrolyzing the esters of 4-hydroxybenzoic acid (parabens). | The Journal of biological chemistry 20030411 |
Role of ceramide in mediating apoptosis of irradiated LNCaP prostate cancer cells. | Cell death and differentiation 20030201 |
Enzymatic digestion of adult human articular cartilage yields a small fraction of the total available cells. | Connective tissue research 20030101 |
Increased expression of the cGMP-inhibited cAMP-specific (PDE3) and cGMP binding cGMP-specific (PDE5) phosphodiesterases in models of pulmonary hypertension. | British journal of pharmacology 20021201 |
Purification and characterization of a collagenase from the mackerel, Scomber japonicus. | Journal of biochemistry and molecular biology 20021130 |
Involvement of proteases in the action of IFN-gamma on WISH cells. | Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20020801 |
High glucose induced nuclear factor kappa B mediated inhibition of endothelial cell migration. | Atherosclerosis 20020601 |
Purification and characterization of a collagenolytic protease from the filefish, Novoden modestrus. | Journal of biochemistry and molecular biology 20020331 |
Activation of chymotrypsin-like serine protease(s) during apoptosis detected by affinity-labeling of the enzymatic center with fluoresceinated inhibitor. | International journal of oncology 20020201 |
A critical role for ethylene in hydrogen peroxide release during programmed cell death in tomato suspension cells. | Planta 20020201 |
Suppression of sulfur mustard-increased IL-8 in human keratinocyte cell cultures by serine protease inhibitors: implications for toxicity and medical countermeasures. | Cell biology and toxicology 20020101 |
Sequential activation of caspases and serine proteases (serpases) during apoptosis. | Cell cycle (Georgetown, Tex.) 20020101 |
Combined modulation of the mesangial machinery for monocyte recruitment by inhibition of NF-kappaB. | American journal of physiology. Cell physiology 20011201 |
Nuclear factor kappa B is involved in lipopolysaccharide-stimulated induction of interferon regulatory factor-1 and GAS/GAF DNA-binding in human umbilical vein endothelial cells. | British journal of pharmacology 20011201 |
Involvement of TLCK-sensitive serine protease in colchicine-induced cell death of sympathetic neurons in culture. | Journal of neuroscience research 20011115 |
Digestive proteinases of red shrimp Pleoticus muelleri (Decapoda, Penaeoidea): partial characterization and relationship with molting. | Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20011001 |
Ethanol-induced apoptosis in hepatoma cells proceeds via intracellular Ca(2+) elevation, activation of TLCK-sensitive proteases, and cytochrome c release. | Experimental cell research 20011001 |
Fas aggregation does not correlate with Fas-mediated apoptosis. | Journal of immunology (Baltimore, Md. : 1950) 20010701 |
Homocysteine induces monocyte chemoattractant protein-1 expression by activating NF-kappaB in THP-1 macrophages. | American journal of physiology. Heart and circulatory physiology 20010601 |
Protease-active extracellular protein preparations from Porphyromonas gingivalis W83 induce N-cadherin proteolysis, loss of cell adhesion, and apoptosis in human epithelial cells. | Journal of periodontology 20010501 |
A serine protease inhibitor, N-alpha-tosyl-l-lysine chloromethyl ketone, prolongs rat hepatic allograft survival. | The Journal of surgical research 20010401 |
Effect of serine protease inhibitors on posttraumatic brain injury and neuronal apoptosis. | Experimental neurology 20010201 |
Protective action of the serine protease inhibitor N-tosyl-L-lysine chloromethyl ketone (TLCK) against acute soman poisoning. | Journal of applied toxicology : JAT 20010101 |
Coaggregation of Porphyromonas gingivalis and Prevotella intermedia. | Microbiology and immunology 20010101 |
Inhibitors of trypsin-like serine proteases prevent DNA damage-induced neuronal death by acting upstream of the mitochondrial checkpoint and of p53 induction. | Neuroscience 20010101 |
Interleukin (IL)-10 inhibits IL-6 production in microglia by preventing activation of NF-kappaB. | Brain research. Molecular brain research 20000414 |
A role for serine proteases in mediating phorbol ester-induced differentiation of HL-60 cells. | Experimental cell research 20000410 |
Evidence that non-caspase proteases are required for chromatin degradation during apoptosis. | Cell death and differentiation 19981201 |
Inhibitors and specificity of Pseudomonas aeruginosa LasA. | The Journal of biological chemistry 19970411 |
Thiol modulation of TNF alpha and IL-1 induced MnSOD gene expression and activation of NF-kappa B. | Molecular and cellular biochemistry 19950705 |
Effect of serine protease inhibitor, N-alpha-tosyl-L-lysyl-chloromethyl ketone (TLCK), on cell-mediated and cell-free HIV-1 spread. | Cellular immunology 19940415 |
Protease activities in carp retina. | Neurochemistry international 19921201 |
Different enzyme classes associated with human natural killer cells may mediate disparate functions. | Journal of immunology (Baltimore, Md. : 1950) 19840301 |