N-Tosyl-L-phenylalanine chloromethyl ketone
Title | Journal |
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Nickel ion inhibits nuclear factor-kappa B activity in human oral squamous cell carcinoma. | PloS one 20130101 |
Optimization of thiazole analogues of resveratrol for induction of NAD(P)H:quinone reductase 1 (QR1). | Bioorganic & medicinal chemistry 20121215 |
Regulation of double-stranded RNA dependent protein kinase expression and attenuation of protein synthesis induced by bacterial toll-like receptors agonists in the absence of interferon. | Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 20121001 |
Identification of UV-protective activators of nuclear factor erythroid-derived 2-related factor 2 (Nrf2) by combining a chemical library screen with computer-based virtual screening. | The Journal of biological chemistry 20120921 |
TPCK inhibits AGC kinases by direct activation loop adduction at phenylalanine-directed cysteine residues. | FEBS letters 20120921 |
Anti-inflammatory sesquiterpene lactones from the flower of Vernonia cinerea. | Bioorganic & medicinal chemistry letters 20120901 |
Identification, synthesis, and biological evaluation of the metabolites of 3-amino-6-(3'-aminopropyl)-5H-indeno[1,2-c]isoquinoline-5,11-(6H)dione (AM6-36), a promising rexinoid lead compound for the development of cancer chemotherapeutic and chemopreventive agents. | Journal of medicinal chemistry 20120628 |
Optimization of the aromatase inhibitory activities of pyridylthiazole analogues of resveratrol. | Bioorganic & medicinal chemistry 20120401 |
Creation of an artificial metalloprotein with a Hoveyda-Grubbs catalyst moiety through the intrinsic inhibition mechanism of α-chymotrypsin. | Chemical communications (Cambridge, England) 20120204 |
Anti-inflammatory mechanism of 15,16-epoxy-3α-hydroxylabda-8,13(16),14-trien-7-one via inhibition of LPS-induced multicellular signaling pathways. | Journal of natural products 20120127 |
Human foetal intestinal fibroblasts are hyper-responsive to lipopolysaccharide stimulation. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20120101 |
Optimizing thiadiazole analogues of resveratrol versus three chemopreventive targets. | Bioorganic & medicinal chemistry 20120101 |
Apolipoprotein A-I stimulates cholesteryl ester transfer protein and apolipoprotein E secretion from lipid-loaded macrophages; the role of NF-κB and PKA signaling pathways. | Biochemical and biophysical research communications 20111125 |
Antimetastatic effect and mechanism of ovatodiolide in MDA-MB-231 human breast cancer cells. | Chemico-biological interactions 20111115 |
Design, synthesis, and biological evaluation of callophycin A and analogues as potential chemopreventive and anticancer agents. | Bioorganic & medicinal chemistry 20111101 |
Bortezomib: understanding the mechanism of action. | Molecular cancer therapeutics 20111101 |
Effects of β-glucosidase hydrolyzed products of harpagide and harpagoside on cyclooxygenase-2 (COX-2) in vitro. | Bioorganic & medicinal chemistry 20110815 |
HMGB-1 induces IL-6 production in human synovial fibroblasts through c-Src, Akt and NF-κB pathways. | Journal of cellular physiology 20110801 |
Experimental autoimmune encephalomyelitis: association with mutual regulation of RelA (p65)/NF-κB and phospho-IκB in the CNS. | Biochemical and biophysical research communications 20110729 |
Nuclear factor kappa B plays a pivotal role in polyinosinic-polycytidylic acid-induced expression of human β-defensin 2 in intestinal epithelial cells. | Clinical and experimental immunology 20110701 |
Expression of trypsin-like serine peptidases in pre-imaginal stages of Aedes aegypti (Diptera: Culicidae). | Archives of insect biochemistry and physiology 20110401 |
Bioactive compounds from the fern Lepisorus contortus. | Journal of natural products 20110225 |
Potential chemopreventive agents based on the structure of the lead compound 2-bromo-1-hydroxyphenazine, isolated from Streptomyces species, strain CNS284. | Journal of medicinal chemistry 20101223 |
Caspase-3 triggers a TPCK-sensitive protease pathway leading to degradation of the BH3-only protein puma. | Apoptosis : an international journal on programmed cell death 20101201 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
Collagenolytic activity in sonic extracts of Tannerella forsythia. | Archives of oral biology 20100801 |
The classical NFkappaB pathway is required for phloroglucinol-induced activation of murine lymphocytes. | Biochimica et biophysica acta 20100701 |
Trypsin and chymotrypsin are involved in the progesterone-induced acrosome reaction in canine spermatozoa. | Reproduction in domestic animals = Zuchthygiene 20100601 |
TPCK targets elements of mitotic spindle and induces cell cycle arrest in prometaphase. | Biochemical and biophysical research communications 20100514 |
High glucose promotes intracellular lipid accumulation in vascular smooth muscle cells by impairing cholesterol influx and efflux balance. | Cardiovascular research 20100401 |
Cathepsin G-mediated enhanced TGF-beta signaling promotes angiogenesis via upregulation of VEGF and MCP-1. | Cancer letters 20100227 |
Okadaic acid induces DNA fragmentation via caspase-3-dependent and caspase-3-independent pathways in Chinese hamster ovary (CHO)-K1 cells. | The FEBS journal 20100101 |
Inflammatory responses in embryonal cardiomyocytes exposed to LPS challenge: an in vitro model of deciphering the effects of LPS on the heart. | Current pharmaceutical design 20100101 |
N(alpha)-tosyl-L-phenylalanine chloromethyl ketone induces caspase-dependent apoptosis in transformed human B cell lines with transcriptional down-regulation of anti-apoptotic HS1-associated protein X-1. | The Journal of biological chemistry 20091009 |
TPCK-induced apoptosis and labelling of the largest subunit of RNA polymerase II in Jurkat cells. | Apoptosis : an international journal on programmed cell death 20091001 |
N-tosyl-L-phenylalanine chloromethyl ketone inhibits NF-kappaB activation by blocking specific cysteine residues of IkappaB kinase beta and p65/RelA. | Biochemistry 20090804 |
IL1B promoter polymorphism regulates the expression of gastric acid stimulating hormone gastrin. | The international journal of biochemistry & cell biology 20090701 |
Osteopontin increases lung cancer cells migration via activation of the alphavbeta3 integrin/FAK/Akt and NF-kappaB-dependent pathway. | Lung cancer (Amsterdam, Netherlands) 20090601 |
The role of Bcl-xL and nuclear factor-kappaB in the effect of taxol on the viability of dendritic cells. | Journal of veterinary science 20090601 |
Synthesis and biological evaluation of reversible inhibitors of IdeS, a bacterial cysteine protease and virulence determinant. | Bioorganic & medicinal chemistry 20090501 |
Differential regulation of high glucose-induced glyceraldehyde-3-phosphate dehydrogenase nuclear accumulation in Müller cells by IL-1beta and IL-6. | Investigative ophthalmology & visual science 20090401 |
Cathepsin G recruits osteoclast precursors via proteolytic activation of protease-activated receptor-1. | Cancer research 20090401 |
Nuclear factor-kappaB mediates cytoprotection of hydrogen peroxide preconditioning against apoptosis induced by oxidative stress in PC12 cells. | Clinical and experimental pharmacology & physiology 20090301 |
Sodium deoxycholate causes nitric oxide mediated DNA damage in oesophageal cells. | Free radical research 20090301 |
f-Met-Leu-Phe stimulates nitric oxide production in chick embryo neurons: the role of NF-kB. | Immunopharmacology and immunotoxicology 20090101 |
Serine protease inhibitors N-alpha-tosyl-L-lysinyl-chloromethylketone (TLCK) and N-tosyl-L-phenylalaninyl-chloromethylketone (TPCK) do not inhibit caspase-3 and caspase-7 processing in cells exposed to pro-apoptotic inducing stimuli. | Journal of cellular biochemistry 20081215 |
Transcriptional and post-translational regulation of Flip, an inhibitor of Fas-mediated apoptosis, in human gut inflammation. | Gut 20081201 |
Treatment with N-tosyl-l-phenylalanine chloromethyl ketone after the onset of collagen-induced arthritis reduces joint erosion and NF-kappaB activation. | European journal of pharmacology 20081024 |
Treatment of cells with n-alpha-tosyl-L-phenylalanine-chloromethyl ketone induces the proteolytic loss of STAT6 transcription factor. | Molecular immunology 20080901 |
Na-Tosyl-Phe chloromethyl ketone prevents granule movement and mast cell synergistic degranulation elicited by costimulation of antigen and adenosine. | Life sciences 20080815 |
Pentoxifylline downregulates alpha (I) collagen expression by the inhibition of Ikappabalpha degradation in liver stellate cells. | Cell biology and toxicology 20080801 |
Development of a cell death-based method for the screening of nuclear factor-kappaB inhibitors. | Journal of immunological methods 20080601 |
Rapidly alternating transmission mode electron-transfer dissociation and collisional activation for the characterization of polypeptide ions. | Analytical chemistry 20080501 |
Serine protease inhibitors N-alpha-tosyl-L-lysinyl-chloromethylketone (TLCK) and N-tosyl-L-phenylalaninyl-chloromethylketone (TPCK) are potent inhibitors of activated caspase proteases. | Journal of cellular biochemistry 20080401 |
Effect of protease inhibitors on exflagellation in Plasmodium falciparum. | Molecular and biochemical parasitology 20080401 |
Comparison of suppressive effects of demethoxycurcumin and bisdemethoxycurcumin on expressions of inflammatory mediators in vitro and in vivo. | Archives of pharmacal research 20080401 |
Myricetin down-regulates phorbol ester-induced cyclooxygenase-2 expression in mouse epidermal cells by blocking activation of nuclear factor kappa B. | Journal of agricultural and food chemistry 20071114 |
On-plate digestion of proteins using novel trypsin-immobilized magnetic nanospheres for MALDI-TOF-MS analysis. | Proteomics 20071001 |
NF-kappaB pathway is involved in griseofulvin-induced G2/M arrest and apoptosis in HL-60 cells. | Journal of cellular biochemistry 20070801 |
Probing the structure and activity of trypsin with amidination. | Analytical biochemistry 20070801 |
Investigation of interleukin 1beta-mediated regulation of NF-kappaB activation in colonic cells reveals divergence between PKB and PDK-transduced events. | Molecular and cellular biochemistry 20070601 |
Inhibition of human erythrocyte invasion by Babesia divergens using serine protease inhibitors. | Molecular and biochemical parasitology 20070501 |
[Effect of N-tosyl-L-phenylalnylchloromethyl ketone and dexamethasone on expression of nuclear transcription factor-kappaB in childhood acute lymphoblastic leukemia and its significance]. | Zhongguo shi yan xue ye xue za zhi 20070401 |
N-tosyl-L-phenylalanyl-chloromethyl ketone reduces ceramide during hypoxic-ischemic brain injury in newborn rat. | European journal of pharmacology 20061203 |
Macrophage-activating lipopeptide-2 induces cyclooxygenase-2 and prostaglandin E(2) via toll-like receptor 2 in human placental trophoblast cells. | Journal of reproductive immunology 20061201 |
Nitric oxide-induced down-regulation of beta-catenin in colon cancer cells by a proteasome-independent specific pathway. | Gastroenterology 20061001 |
Genetic and environmental influences on therapeutic and toxicity outcomes: studies with CYP2A6. | Current clinical pharmacology 20060901 |
TNF-alpha-independent IL-8 expression: alterations in bacterial challenge dose cause differential human monocytic cytokine response. | Journal of immunology (Baltimore, Md. : 1950) 20060715 |
Aspirin and PPAR-alpha activators inhibit monocyte chemoattractant protein-1 expression induced by high glucose concentration in human endothelial cells. | Vascular pharmacology 20060601 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
Cross-interaction between PAR-activation and tyrosine kinase in the modulation of rat ileum smooth muscle contraction. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20060401 |
Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARalpha and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways. | Journal of cellular biochemistry 20060201 |
Differentiation and protease production in Micromonospora echinospora (ATCC 15837). | Antonie van Leeuwenhoek 20060101 |
Plasmodium berghei: effect of protease inhibitors during gametogenesis and early zygote development. | Experimental parasitology 20051201 |
Suppression of urokinase receptor expression by thalidomide is associated with inhibition of nuclear factor kappaB activation and subsequently suppressed ovarian cancer dissemination. | Cancer research 20051115 |
4-Hydroxyestradiol induces oxidative stress and apoptosis in human mammary epithelial cells: possible protection by NF-kappaB and ERK/MAPK. | Toxicology and applied pharmacology 20051001 |
Simvastatin induces interleukin-18 production in human peripheral blood mononuclear cells. | Clinical immunology (Orlando, Fla.) 20050901 |
Characterization of a monolithic immobilized trypsin microreactor with on-line coupling to ESI-MS. | Journal of separation science 20050901 |
Human immunodeficiency virus-1 Tat protein up-regulates interleukin-6 and interleukin-8 expression in human breast cancer cells. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20050901 |
Pancreatic trypsin activates human promatrix metalloproteinase-2. | Journal of molecular biology 20050722 |
A biphasic role of nuclear transcription factor (NF)-kappaB in the islet beta-cell apoptosis induced by interleukin (IL)-1beta. | Journal of cellular physiology 20050701 |
Can application of serine protease inhibitors TPCK and TLCK provide evidence for possible involvement of serine protease Omi/HtrA2 in imatinib mesylate-induced cell death of BCR-ABL-positive human leukemia cells? | Leukemia 20050601 |
Thalidomide inhibits tumor necrosis factor-alpha-induced interleukin-8 expression in endometriotic stromal cells, possibly through suppression of nuclear factor-kappaB activation. | The Journal of clinical endocrinology and metabolism 20050501 |
Potential mechanism of blood vessel protection by resveratrol, a component of red wine. | Annals of the New York Academy of Sciences 20050501 |
Direct effects of polymyxin B on human dendritic cells maturation. The role of IkappaB-alpha/NF-kappaB and ERK1/2 pathways and adhesion. | The Journal of biological chemistry 20050408 |
Another biological effect of tosylphenylalanylchloromethane (TPCK): it prevents p47phox phosphorylation and translocation upon neutrophil stimulation. | The Biochemical journal 20050315 |
Manganese potentiates in vitro production of proinflammatory cytokines and nitric oxide by microglia through a nuclear factor kappa B-dependent mechanism. | Toxicological sciences : an official journal of the Society of Toxicology 20050301 |
Differential effect of LFA703, pravastatin, and fluvastatin on production of IL-18 and expression of ICAM-1 and CD40 in human monocytes. | Journal of leukocyte biology 20050301 |
Mechanism of concentration-dependent induction of heme oxygenase-1 by resveratrol in human aortic smooth muscle cells. | Biochemical pharmacology 20050101 |
alpha1-Adrenergic receptor antagonists induce production of IL-18 and expression of ICAM-1 and CD40 in human monocytes. | Journal of immunotherapy (Hagerstown, Md. : 1997) 20050101 |
Caspase-independent retinal ganglion cell death after target ablation in the neonatal rat. | The European journal of neuroscience 20050101 |
Modulation of tryptase release from human tonsil mast cells by protease inhibitors. | Pharmacological reports : PR 20050101 |
Pro- and anti-apoptotic effects of an inhibitor of chymotrypsin-like serine proteases. | Cell cycle (Georgetown, Tex.) 20041201 |
Modulation of tryptase and histamine release from human lung mast cells by protease inhibitors. | Asian Pacific journal of allergy and immunology 20041201 |
Expression of anti-apoptotic factors in cells parasitized by second-generation schizonts of Eimeria tenella and Eimeria necatrix. | Veterinary parasitology 20041110 |
Do alkylating agents modify the histidine residue of the desensitized butyrylcholinesterase? | The protein journal 20041101 |
L-ascorbic acid represses constitutive activation of NF-kappaB and COX-2 expression in human acute myeloid leukemia, HL-60. | Journal of cellular biochemistry 20041001 |
Lipopolysaccharide-promoted proliferation of endometriotic stromal cells via induction of tumor necrosis factor alpha and interleukin-8 expression. | Fertility and sterility 20041001 |
Multiple effects of N-alpha-tosyl-L-phenylalanyl chloromethyl ketone (TPCK) on apoptotic pathways in human prostatic carcinoma cell lines. | Cancer biology & therapy 20040801 |
On the trail of cell death pathways in prostate cancer. | Cancer biology & therapy 20040801 |
Reactive oxygen species mediate chloroquine-induced expression of chemokines by human astroglial cells. | Glia 20040701 |
A novel 'clip-and-link' activity of repeat in toxin (RTX) proteins from gram-negative pathogens. Covalent protein cross-linking by an Asp-Lys isopeptide bond upon calcium-dependent processing at an Asp-Pro bond. | The Journal of biological chemistry 20040611 |
Proteinase inhibitors TPCK and TLCK prevent Entamoeba histolytica induced disturbance of tight junctions and microvilli in enteric cell layers in vitro. | International journal for parasitology 20040601 |
Neuregulin signaling on glucose transport in muscle cells. | The Journal of biological chemistry 20040326 |
A reporter-based assay for identifying hepatitis C virus inhibitors based on subgenomic replicon cells. | Journal of virological methods 20040301 |
Poly(ethylene glycol)-supported enzyme inactivators. Efficient identification of the site of covalent attachment to alpha-chymotrypsin by PEG-TPCK. | Bioconjugate chemistry 20040101 |
Possible role of NF-kappaB in Bcl-X(L) protection against hydrogen peroxide-induced PC12 cell death. | Redox report : communications in free radical research 20040101 |
Effect of N-tosyl-L-phenylalanylchloromethyl ketone on tumor necrosis factor-alpha -induced NF-kappaB activation and apoptosis in U937 cell line. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20040101 |
Toll-like receptor 4-dependent activation of macrophages by polysaccharide isolated from the radix of Platycodon grandiflorum. | International immunopharmacology 20031201 |
Induction of RANTES/CCL5 by herpes simplex virus is regulated by nuclear factor kappa B and interferon regulatory factor 3. | The Journal of general virology 20030901 |
Integrins induce expression of monocyte chemoattractant protein-1 via focal adhesion kinase in mesangial cells. | Kidney international 20030801 |
The role of nuclear factor-kappa B in interleukin-8 expression by human adenoidal fibroblasts. | The Laryngoscope 20030801 |
Dephosphorylation of p53 during cell death by N-alpha-tosyl-L-phenylalanyl chloromethyl ketone. | Biochemical and biophysical research communications 20030711 |
Alcohol consumption decreases IL-2-induced NF-kappaB activity in enriched NK cells from C57BL/6 mice. | Toxicological sciences : an official journal of the Society of Toxicology 20030501 |
Effect of protease-activated receptors on guinea-pig ileum contraction in vitro. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20030401 |
Tumor necrosis factor-alpha-induced interleukin-8 (IL-8) expression in endometriotic stromal cells, probably through nuclear factor-kappa B activation: gonadotropin-releasing hormone agonist treatment reduced IL-8 expression. | The Journal of clinical endocrinology and metabolism 20030201 |
Treatment of hypoxic-ischemic brain injury in newborn rats with TPCK 3 h after hypoxia decreases caspase-9 activation and improves neuropathologic outcome. | Developmental neuroscience 20030101 |
Inhibitor of nuclear factor-Kappa B activation attenuates venular constriction, leukocyte rolling-adhesion and microvessel rupture induced by ethanol in intact rat brain microcirculation: relation to ethanol-induced brain injury. | Neuroscience letters 20021206 |
Increased expression of the cGMP-inhibited cAMP-specific (PDE3) and cGMP binding cGMP-specific (PDE5) phosphodiesterases in models of pulmonary hypertension. | British journal of pharmacology 20021201 |
Constitutively active NFkappa B is required for the survival of S-type neuroblastoma. | The Journal of biological chemistry 20021101 |
N-tosyl-L-phenylalanyl-chloromethyl ketone eliminates the increase in caspase-3 and bcl-2 caused by brain injury in the newborn rat. | Pharmacology 20021101 |
CancerB increases production of nitric oxide and tumor necrosis factor-alpha in peritoneal macrophages. | Clinica chimica acta; international journal of clinical chemistry 20020801 |
PS-341, a novel proteasome inhibitor, induces Bcl-2 phosphorylation and cleavage in association with G2-M phase arrest and apoptosis. | Molecular cancer therapeutics 20020801 |
NF-kappaB p50 and p52 expression is not required for RANK-expressing osteoclast progenitor formation but is essential for RANK- and cytokine-mediated osteoclastogenesis. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20020701 |
Lipopolysaccharide down regulates both scavenger receptor B1 and ATP binding cassette transporter A1 in RAW cells. | Infection and immunity 20020601 |
IL-17 stimulates inflammatory responses via NF-kappaB and MAP kinase pathways in human colonic myofibroblasts. | American journal of physiology. Gastrointestinal and liver physiology 20020601 |
Indomethacin lowers the threshold thermal exposure for hyperthermic radiosensitization and heat-shock inhibition of ionizing radiation-induced activation of NF-kappaB. | International journal of radiation biology 20020601 |
TLR4-dependent lipopolysaccharide signalling in epithelial cells is independent of extracellular protease activity. | Cellular microbiology 20020501 |
Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells. | The Journal of biological chemistry 20020419 |
Activation of chymotrypsin-like serine protease(s) during apoptosis detected by affinity-labeling of the enzymatic center with fluoresceinated inhibitor. | International journal of oncology 20020201 |
MCP-1 but not CINC synthesis is increased in rat pancreatic acini in response to cerulein hyperstimulation. | American journal of physiology. Gastrointestinal and liver physiology 20020101 |
Mutational analysis of the C-domain in nonribosomal peptide synthesis. | European journal of biochemistry 20020101 |
Sequential activation of caspases and serine proteases (serpases) during apoptosis. | Cell cycle (Georgetown, Tex.) 20020101 |
NF-kappaB activation for constitutive expression of VCAM-1 and ICAM-1 on B lymphocytes and plasma cells. | Biochemical and biophysical research communications 20011214 |
Involvement of TLCK-sensitive serine protease in colchicine-induced cell death of sympathetic neurons in culture. | Journal of neuroscience research 20011115 |
Digestive proteinases of red shrimp Pleoticus muelleri (Decapoda, Penaeoidea): partial characterization and relationship with molting. | Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20011001 |
Multiple caspases are involved in beta-amyloid-induced neuronal apoptosis. | Journal of neuroscience research 20010701 |
High constitutive level of NF-kappaB is crucial for viability of adenocarcinoma cells. | Cell death and differentiation 20010601 |
Disruption of 3-phosphoinositide-dependent kinase 1 (PDK1) signaling by the anti-tumorigenic and anti-proliferative agent n-alpha-tosyl-l-phenylalanyl chloromethyl ketone. | The Journal of biological chemistry 20010413 |
Human immunodeficiency virus type 1 Tat protein decreases cyclic AMP synthesis in rat microglia cultures. | Journal of neurochemistry 20010401 |
Cell-specific caspase expression by different neuronal phenotypes in transient retinal ischemia. | Journal of neurochemistry 20010401 |
Induction of IRF-3/-7 kinase and NF-kappaB in response to double-stranded RNA and virus infection: common and unique pathways. | Genes to cells : devoted to molecular & cellular mechanisms 20010401 |
Stromal cell-derived factor 1 alpha-induced chemotaxis in T cells is mediated by nitric oxide signaling pathways. | Journal of immunology (Baltimore, Md. : 1950) 20010301 |
Cell transformation induced by hepatitis C virus NS3 serine protease. | Journal of viral hepatitis 20010301 |
Prostaglandin levels in stimulated macrophages are controlled by phospholipase A2-activating protein and by activation of phospholipase C and D. | The Journal of biological chemistry 20010223 |
Effect of serine protease inhibitors on posttraumatic brain injury and neuronal apoptosis. | Experimental neurology 20010201 |
Relationship between NF-kappaB and trypsinogen activation in rat pancreas after supramaximal caerulein stimulation. | Biochemical and biophysical research communications 20010112 |
Effect of enzyme inhibitors on protein quaternary structure determined by on-line size exclusion chromatography-microelectrospray ionization mass spectrometry. | Journal of the American Society for Mass Spectrometry 20010101 |
Inhibitors of caspase homologues suppress an apoptotic phenotype in cultured rabbit corpora lutea. | Reproduction, fertility, and development 20010101 |
Selective involvement of reactive oxygen intermediates in platelet-activating factor-mediated activation of NF-kappaB. | Inflammation 20001001 |
Interleukin (IL)-10 inhibits IL-6 production in microglia by preventing activation of NF-kappaB. | Brain research. Molecular brain research 20000414 |
A role for serine proteases in mediating phorbol ester-induced differentiation of HL-60 cells. | Experimental cell research 20000410 |
NF-kappa B modulates TNF-alpha production by alveolar macrophages in asymptomatic HIV-seropositive individuals. | Journal of immunology (Baltimore, Md. : 1950) 20000201 |
Effects of retinoic acid on N-glycosylation and mRNA stability of the liver/bone/kidney alkaline phosphatase in neuronal cells. | Journal of cellular physiology 20000101 |
Effect of the serine protease inhibitor N-tosyl-l-phenylalanine-chloromethyl ketone (TPCK) on MCF-7 mammary tumour cells growth and differentiation. | Cell biology international 20000101 |
Tumor necrosis factor induces DNA replication in hepatic cells through nuclear factor kappaB activation. | Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 19991201 |
Expression and release of chemokines associated with apoptotic cell death in human promonocytic U937 cells and peripheral blood mononuclear cells. | European journal of immunology 19991001 |
Overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma is regulated by constitutively activated RelA. | Oncogene 19990812 |
The host environment promotes the constitutive activation of nuclear factor-kappaB and proinflammatory cytokine expression during metastatic tumor progression of murine squamous cell carcinoma. | Cancer research 19990715 |
N-acetylcysteine blocks apoptosis induced by N-alpha-tosyl-L-phenylalanine chloromethyl ketone in transformed T-cells. | Cell death and differentiation 19990401 |
Evidence that non-caspase proteases are required for chromatin degradation during apoptosis. | Cell death and differentiation 19981201 |
Distinct steps in DNA fragmentation pathway during camptothecin-induced apoptosis involved caspase-, benzyloxycarbonyl- and N-tosyl-L-phenylalanylchloromethyl ketone-sensitive activities. | Cancer research 19980715 |
Proteolytic cleavage of HsRad51 during apoptosis. | FEBS letters 19980508 |
Tyrosine phosphatase-dependent/tyrosine kinase-independent induction of nuclear factor-kappa B by tumor necrosis factor-alpha: effects on prostaglandin endoperoxide synthase-2 mRNA accumulation. | The Journal of pharmacology and experimental therapeutics 19980501 |
Cryptosporidium parvum metalloaminopeptidase inhibitors prevent in vitro excystation. | Antimicrobial agents and chemotherapy 19961201 |
Role of serine and ICE-like proteases in induction of apoptosis by etoposide in human leukemia HL-60 cells. | Leukemia 19960501 |
Thiol modulation of TNF alpha and IL-1 induced MnSOD gene expression and activation of NF-kappa B. | Molecular and cellular biochemistry 19950705 |
Murine epidermal xanthine oxidase activity: correlation with degree of hyperplasia induced by tumor promoters. | Cancer research 19871201 |