Nafamostat mesilate, a noncalcium compound, as an anticoagulant, induces calcium-dependent haemolysis when infused with packed erythrocytes.

Transfusion medicine (Oxford, England) 20120601

An NF-κB pathway-mediated positive feedback loop amplifies Ras activity to pathological levels in mice.

The Journal of clinical investigation 20120402

[Could nafamostat or gabexate prevent the post endoscopic retrograde cholangiopancreatography pancreatitis?].

The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20120301

Proteolytic activation of the epithelial sodium channel and therapeutic application of a serine protease inhibitor for the treatment of salt-sensitive hypertension.

Clinical and experimental nephrology 20120201

Duodenal myotomy blocks reduction of meal size and prolongation of intermeal interval by cholecystokinin.

Physiology & behavior 20120201

Antitumoral efficacy of the protease inhibitor gabexate mesilate in colon cancer cells harbouring KRAS, BRAF and PIK3CA mutations.

PloS one 20120101

Effect of synthetic protease inhibitor gabexate mesilate on attenuation of coagulant activity and cytokine release in a rat model of islet transplantation.

Transplantation proceedings 20111101

Oral delivery system for two-pulse colonic release of protein drugs and protease inhibitor/absorption enhancer compounds.

Journal of pharmaceutical sciences 20110801

Role of TRPV1 in nociception and edema induced by monosodium urate crystals in rats.

Pain 20110801

The short term satiety peptide cholecystokinin reduces meal size and prolongs intermeal interval.

Peptides 20110601

Is entirely conservative management a correct strategy for hemodynamically stable patient with a grade IV blunt pancreatic injury?

World journal of surgery 20110401

ONO 3403, a synthetic serine protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-{alpha} and nitric oxide production and protects mice from lethal endotoxic shock.

Innate immunity 20110201

[Synthetic protease inhibitors for the treatment of DIC].

Rinsho byori. The Japanese journal of clinical pathology 20110201

Gabexate mesilate inhibits the expression of HMGB1 in lipopolysaccharide-induced acute lung injury.

The Journal of surgical research 20110101

The effects of gabexate mesilate on the microsurgical reconstruction of the hepatic artery in living donor liver transplantation.

Transplantation proceedings 20101201

Effects of a synthetic protease inhibitor (gabexate mesilate) and a neutrophil elastase inhibitor (sivelestat sodium) on acid-induced lung injury in rats.

European journal of pharmacology 20100901

Regulator of calcineurin 1 controls growth plasticity of adult pancreas.

Gastroenterology 20100801

Release of interleukin-1 receptor antagonist by combining a leukocyte adsorption carrier with ulinastatin.

Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy 20100801

Refractory chronic urticaria treated effectively with the protease inhibitors, nafamostat mesilate and camostat mesilate.

Acta dermato-venereologica 20100701

Lack of therapeutic effects of gabexate mesilate on the hepatic encephalopathy in rats with acute and chronic hepatic failure.

Journal of gastroenterology and hepatology 20100701

Tumor-derived trypsin enhances proliferation of intrahepatic cholangiocarcinoma cells by activating protease-activated receptor-2.

International journal of oncology 20100401

Efficacy of camostat mesilate against dyspepsia associated with non-alcoholic mild pancreatic disease.

Journal of gastroenterology 20100301

Post-ERCP pancreatitis.

Journal of hepato-biliary-pancreatic sciences 20100101

[Treatment of disseminated intravascular coagulation].

[Rinsho ketsueki] The Japanese journal of clinical hematology 20100101

Stability of gabexate mesilate products: Influence of the addition of mannitol.

Bio-medical materials and engineering 20100101

C5a-inhibitory peptide combined with gabexate mesilate prevents the instant blood-mediated inflammatory reaction in a rat model of islet transplantation.

Transplantation proceedings 20100101

The specific inhibition of HepG2 cells proliferation by apoptosis induced by gabexate mesilate.

International journal of clinical and experimental pathology 20100101

[Treatment of DIC associated with myelogenous leukemia].

Nihon rinsho. Japanese journal of clinical medicine 20091001

Continuous regional arterial infusion therapy for acute necrotizing pancreatitis due to Mycoplasma pneumoniae infection in a child.

Cardiovascular and interventional radiology 20090501

Camostat attenuates airway epithelial sodium channel function in vivo through the inhibition of a channel-activating protease.

The Journal of pharmacology and experimental therapeutics 20090501

Active site conformational changes of prostasin provide a new mechanism of protease regulation by divalent cations.

Protein science : a publication of the Protein Society 20090501

Camostat mesilate inhibits prostasin activity and reduces blood pressure and renal injury in salt-sensitive hypertension.

Journal of hypertension 20090101

C5a inhibitory peptide combined with gabexate mesilate is a clinically available candidate for preventing the instant blood-mediated inflammatory reaction.

Transplantation proceedings 20090101

Modelling of tumour--host coexistence In vitro in the presence of serine protease inhibitors.

In vivo (Athens, Greece) 20090101

Continuous regional arterial infusion therapy with gabexate mesilate for severe acute pancreatitis.

World journal of gastroenterology 20081107

Choledochoscope manometry about different drugs on the Sphincter of Oddi.

World journal of gastroenterology 20081014

Activation of submucosal but not myenteric plexus of the gastrointestinal tract accompanies reduction of food intake by camostat.

Regulatory peptides 20081009

The effects of a new human leukocyte elastase inhibitor (recombinant guamerin) on cerulein-induced pancreatitis in rats.

International immunopharmacology 20080701

Protective effects of amino acids against gabexate mesilate-induced cell injury in porcine aorta endothelial cells.

Journal of pharmacological sciences 20080701

Pharmacological approach to acute pancreatitis.

World journal of gastroenterology 20080521

CCK-induced pancreatic growth is not limited by mitogenic capacity in mice.

American journal of physiology. Gastrointestinal and liver physiology 20080501

Characteristics of gabexate mesilate-induced cell injury in porcine aorta endothelial cells.

Journal of pharmacological sciences 20080301

Somatostatin bolus injection for post-ERCP pancreatitis prevention: a need for further study.

Gastrointestinal endoscopy 20080101

Synthetic serine protease inhibitor, gabexate mesilate, prevents nuclear factor-kappaB activation and increases TNF-alpha-mediated apoptosis in human pancreatic cancer cells.

Digestive diseases and sciences 20071001

Early successes and late failures in the prevention of post endoscopic retrograde cholangiopancreatography.

World journal of gastroenterology 20070714

Antiproteases in preventing post-ERCP acute pancreatitis.

JOP : Journal of the pancreas 20070709

Somatostatin and gabexate for post-endoscopic retrograde cholangiopancreatography pancreatitis prevention: meta-analysis of randomized placebo-controlled trials.

Journal of gastroenterology and hepatology 20070701

Efficacy of postprocedure administration of gabexate mesylate in the prevention of post-ERCP pancreatitis: a randomized, controlled, multicenter study.

Gastrointestinal endoscopy 20070601

The proteinase inhibitor camostat mesilate suppresses pancreatic pain in rodents.

Life sciences 20070501

Translocation of pancreatic juice after ischemia and reperfusion of the intestines and the effects of gabexate mesilate (FOY) in rats.

Transplantation proceedings 20070501

Prophylactic administration of somatostatin or gabexate does not prevent pancreatitis after ERCP: an updated meta-analysis.

Gastrointestinal endoscopy 20070401

Risk for post-ERCP pancreatitis after needle knife precut sphincterotomy following repeated cannulation attempts.

Journal of clinical gastroenterology 20070401

Pancreatic diabetes in a follow-up survey of chronic pancreatitis in Japan.

Journal of gastroenterology 20070401

Prophylaxis of post-ERCP pancreatic complications with gabexate.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20070301

[Typhoid fever and acute pancreatitis: two cases].

Le infezioni in medicina : rivista periodica di eziologia, epidemiologia, diagnostica, clinica e terapia delle patologie infettive 20070301

Induction of early response genes in trypsin inhibitor-induced pancreatic growth.

American journal of physiology. Gastrointestinal and liver physiology 20070201

Evaluation of serum amylase and gabexate mesilate with endoscopic papillary balloon dilatation.

The journal of medical investigation : JMI 20070201

Gabexate in the prophylaxis of post-ERCP pancreatitis: a meta-analysis of randomized controlled trials.

BMC gastroenterology 20070101

The papilla of Vater just below the pylorus presenting as recurrent duodenal ulcer bleeding.

Internal medicine (Tokyo, Japan) 20070101

Successful intermittent application of the Pringle maneuver for 30 minutes during human hepatectomy: a clinical randomized study with use of a protease inhibitor.

Hepato-gastroenterology 20070101

Successful liver transplantation across the ABO incompatibility barrier in 6 cases of biliary atresia.

Journal of pediatric surgery 20061201

A case of feline pancreatitis.

The Journal of veterinary medical science 20061201

Boerhaave syndrome treated conservatively following early endoscopic diagnosis: a case report.

Journal of Nippon Medical School = Nippon Ika Daigaku zasshi 20061201

Frequency of post-ERCP pancreatitis in a single tertiary referral centre without and with routine prophylaxis with gabexate: a 6-year survey and cost-effectiveness analysis.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20060801

Pharmacological prevention of post-ERCP pancreatitis--an everlasting dream?

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20060801

Serine protease inhibitors nafamostat mesilate and gabexate mesilate attenuate allergen-induced airway inflammation and eosinophilia in a murine model of asthma.

The Journal of allergy and clinical immunology 20060701

[Effects of Chinese herbal medicines on spontaneous chronic pancreatitis in rats and the pathological relationships between formulas and syndromes].

Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20060701

Activation of the mTOR signalling pathway is required for pancreatic growth in protease-inhibitor-fed mice.

The Journal of physiology 20060615

Properties of poly(lactic-co-glycolic acid) nanospheres containing protease inhibitors: camostat mesilate and nafamostat mesilate.

International journal of pharmaceutics 20060511

Effects of gabexate mesilate on ischemia-reperfusion-induced testicular injury in rats.

Pediatric surgery international 20060501

Calcineurin-dependent and calcineurin-independent signal transduction pathways activated as part of pancreatic growth.

Pancreas 20060401

Efficacy of camostat mesilate compared with famotidine for treatment of functional dyspepsia: is camostat mesilate effective?

Journal of gastroenterology and hepatology 20060401

Evidence-based treatment of acute pancreatitis: a look at established paradigms.

Annals of surgery 20060201

Effects of gabexate mesilate on serum inflammatory cytokines in rats with acute necrotizing pancreatitis.

Cytokine 20060121

New approaches for the treatment of acute pancreatitis.

JOP : Journal of the pancreas 20060111

Evaluation of a protease inhibitor in the prevention of ischemia and reperfusion injury in hepatectomy under intermittent Pringle maneuver.

American journal of surgery 20060101

Clinical trial of gabexate in the prophylaxis of post-endoscopic retrograde cholangiopancreatography pancreatitis.

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20060101

A case of severe acute pancreatitis, in overlap syndrome of systemic sclerosis and systemic lupus erythematosus, successfully treated with plasmapheresis.

Modern rheumatology 20060101

Beneficial effect of gabexate mesilate on microscopic polyangiitis with renal dysfunction and pulmonary hemorrhage: A case report.

Angiology 20060101

Pharmacological management of pancreatitis.

Current opinion in pharmacology 20051201

Camostat, an oral trypsin inhibitor, reduces pancreatic fibrosis induced by repeated administration of a superoxide dismutase inhibitor in rats.

Journal of gastroenterology and hepatology 20050601

Water and enzyme secretion are tightly coupled in pancreatic secretion stimulated by food or CCK-58 but not by CCK-8.

American journal of physiology. Gastrointestinal and liver physiology 20050501

Synthetic protease inhibitor camostat prevents and reverses dyslipidemia, insulin secretory defects, and histological abnormalities of the pancreas in genetically obese and diabetic rats.

Metabolism: clinical and experimental 20050501

Effects of gabexate mesilate (FOY) on amylase and phospholipase A2 in human serum and pancreatic juice.

Digestive diseases and sciences 20050501

Gabexate mesilate and acute pancreatitis: an experience of evidence based drug information for improving rational drug use.

Pharmacy world & science : PWS 20050401

Gabexate mesilate, a synthetic protease inhibitor, attenuates carbon tetrachloride-induced liver injury in rats.

Journal of gastroenterology 20050301

Effect of synthetic protease inhibitor gabexate mesilate on the attenuation of ischemia/reperfusion injury in canine kidney autotransplantation.

Surgery 20050201

Preventive and therapeutic effects of the protease inhibitor camostat on pancreatic fibrosis and atrophy in CCK-1 receptor-deficient rats.

Pancreas 20050101

Antimetastatic activity of a synthetic serine protease inhibitor, FOY-305 (Foypan).

In vivo (Athens, Greece) 20050101

Gabexate mesilate hastens recovery from vecuronium-induced neuromuscular blockade.

European journal of anaesthesiology 20050101

Use of low dose dopamine, gabexate mesilate and ulinastatin reduces the water balance and pulmonary complication in thoracic esophagectomy patients.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20050101

[Hepatic portal venous gas--a report of two cases successfully treated with conservative management].

Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20041210

[Essential therapeutic strategies for acute pancreatitis--guidelines for initial treatment and their significance].

Nihon rinsho. Japanese journal of clinical medicine 20041101

[Treatment of acute pancreatitis with protease inhibitor, H2 receptor antagonist and somatostatin analogue].

Nihon rinsho. Japanese journal of clinical medicine 20041101

Treatment of acute pancreatitis with protease inhibitors: a meta-analysis.

European journal of gastroenterology & hepatology 20041101

The effect of continuous arterial infusion of gabexate mesilate (FOY-007) on experimental acute pancreatitis.

The journal of medical investigation : JMI 20040801

Gabexate mesilate inhibits colon cancer growth, invasion, and metastasis by reducing matrix metalloproteinases and angiogenesis.

Clinical cancer research : an official journal of the American Association for Cancer Research 20040701

Tumor protein p53-induced nuclear protein 1 (TP53INP1) in spontaneous chronic pancreatitis in the WBN/Kob rat: drug effects on its expression in the pancreas.

JOP : Journal of the pancreas 20040701

Calcineurin mediates pancreatic growth in protease inhibitor-treated mice.

American journal of physiology. Gastrointestinal and liver physiology 20040501

[Changes in coagulation, fibrinolysis and platelet functions during extracorporeal circulation].

Nihon rinsho. Japanese journal of clinical medicine 20040501

Gabexate mesilate and heparin responsiveness in coronary patients.

Medical science monitor : international medical journal of experimental and clinical research 20040301

[Autoimmune pancreatitis].

Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20040110

Preparation and characterization of starch/cyclodextrin bioadhesive microspheres as platform for nasal administration of Gabexate Mesylate (Foy) in allergic rhinitis treatment.

Biomaterials 20040101

Circulating ethanol does not stimulate pancreatic secretion in conscious rats.

Pancreas 20031101

[A case of severe Chlamydia pneumoniae pneumonia requiring mechanical ventilation and complicated with disseminated intravascular coagulation].

Nihon Kokyuki Gakkai zasshi = the journal of the Japanese Respiratory Society 20031101

CCK-58 is the only detectable endocrine form of cholecystokinin in rat.

American journal of physiology. Gastrointestinal and liver physiology 20030801

Involvement of proteinase-activated receptor-2 in mast cell tryptase-induced barrier dysfunction in bovine aortic endothelial cells.

Cellular signalling 20030801

Nafamostat mesilate is an extremely potent inhibitor of human tryptase.

Journal of pharmacological sciences 20030801

[Prevention of hemorrhage occurring in patients with leukemia].

Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 20030610

Use of gabexate mesylate in Italian hospitals: a multicentre observational study.

Journal of clinical pharmacy and therapeutics 20030601

Effects of bioactive agents on biliary motor function.

Current gastroenterology reports 20030401

Gabexate mesilate, a synthetic protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production by inhibiting activation of both nuclear factor-kappaB and activator protein-1 in human monocytes.

The Journal of pharmacology and experimental therapeutics 20030401

Gabexate mesilate, a synthetic anticoagulant, inhibits the expression of endothelial leukocyte adhesion molecules in vitro.

Critical care medicine 20030401

Systematic skepticism.

Critical care medicine 20030401

Changes in blood viscosity with synthetic protease inhibitors.

Journal of pharmacological sciences 20030401

Morphological relationship between intercalated duct and pancreatic islet in streptozotocin and/or camostat mesilate administrations in the chicken.

Anatomia, histologia, embryologia 20030401

Results of treating severe acute pancreatitis with gabexate is associated with neutrophil apoptosis activity.

Hepato-gastroenterology 20030101

Does gabexate mesilate affect serum concentrations of acute phase proteins after endoscopic retrograde cholangiopancreatography examination?

Hepato-gastroenterology 20030101

Acute pancreatitis occurring in the early postpartum period: a case report.

Journal of perinatal medicine 20030101

Gabexate mesilate (FOY) inhibition of amylase and phospholipase A(2) activity in sow pancreatic juice.

Journal of investigative surgery : the official journal of the Academy of Surgical Research 20030101

A possible defensive mechanism in the basal region of gastric mucosa and the healing of erosions.

Clinical hemorheology and microcirculation 20030101

Gabexate mesilate and/or octreotide in human immunodeficiency virus-associated pancreatic abnormalities.

Alimentary pharmacology & therapeutics 20021001

Gabexate or somatostatin administration before ERCP in patients at high risk for post-ERCP pancreatitis: a multicenter, placebo-controlled, randomized clinical trial.

Gastrointestinal endoscopy 20021001

Biological phenotype determination with ex vivo model in gastric cancer for matrix-metalloproteinase inhibitor treatment.

International journal of molecular medicine 20020901

Early capillary no-reflow during low-flow reperfusion after hind limb ischemia in the rat.

Annals of plastic surgery 20020801

Modulation of L-arginine transport and nitric oxide production by gabexate mesylate.

Biochemical pharmacology 20020715

Hepatocyte protection by a protease inhibitor against ischemia/reperfusion injury of human liver.

Journal of the American College of Surgeons 20020701

Different effects of oral administration of synthetic trypsin inhibitor on the pancreas between cholecystokinin-A receptor gene knockout mice and wild type mice.

Japanese journal of pharmacology 20020701

Predicting and preventing post-ERCP pancreatitis.

Current gastroenterology reports 20020401

Effects of gabexate mesilate, a protease inhibitor, on human sphincter of Oddi motility.

Digestive diseases and sciences 20020401

Novel trial for the treatment of steroid dependency in minimal change disease: combined therapy of camostat mesilate and glycyrrhizin.

Nephron 20020301

Protease inhibition in the intestinal lumen: attenuation of systemic inflammation and early indicators of multiple organ failure in shock.

Shock (Augusta, Ga.) 20020301

[Thoracic aortic aneurysm with chronic disseminated intravascular coagulation treated successfully with orally administered camostat mesilate, warfarin and aspirin].

[Rinsho ketsueki] The Japanese journal of clinical hematology 20020301

Differential cytokine response in host defence mechanisms triggered by gram-negative and gram-positive bacteria, and the roles of gabexate mesilate, a synthetic protease inhibitor.

The Journal of international medical research 20020101

A case of primary Sjögren's syndrome associated with low titer cold agglutinin disease.

Clinical and experimental rheumatology 20020101

Inhibition of natural killer cytotoxicity in vitro by clinical grade serine protease inhibitors.

Haematologia 20020101

Fatal cases of gabexate mesilate-induced anaphylaxis.

International journal of clinical pharmacology research 20020101

Combinatorial synthesis of SSAO inhibitors using sonogashira coupling: SAR of aryl propargylic amines.

Bioorganic & medicinal chemistry letters 20011008

Granulomatous tubulointerstitial nephritis induced by all-trans retinoic acid.

Anti-cancer drugs 20010901

Regional effects of nafamostat, a novel potent protease and complement inhibitor, on severe necrotizing pancreatitis.

Surgery 20010801

Successful treatment of DIC with a serine proteinase inhibitor.

The American journal of emergency medicine 20010701

Prevention of rat hepatic fibrosis by the protease inhibitor, camostat mesilate, via reduced generation of active TGF-beta.

Gastroenterology 20010601

Effects of synthetic serine protease inhibitors on proliferation and collagen synthesis of human pancreatic periacinar fibroblast-like cells.

Pancreas 20010401

Selective inhibition of human mast cell tryptase by gabexate mesylate, an antiproteinase drug.

Biochemical pharmacology 20010201

Preparation and characterization of biodegradable or enteric-coated microspheres containing the protease inhibitor camostat.

The Journal of pharmacy and pharmacology 20010201

[Can post-ERCP acute pancreatitis be predicted and prevented?].

Gastroenterologie clinique et biologique 20010101

[Gabexate mesilate vs gabexate mesilate combined with octreotide in the prevention of postoperative complications of pancreatic surgery: preliminary results].

Chirurgia italiana 20010101

Gabexate mesilate in acute pancreatitis: miracle or mirage?

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20010101

Multicentre comparative study of two schedules of gabexate mesilate in the treatment of acute pancreatitis. Italian Acute Pancreatitis Study Group.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20010101

Inhibition of pig liver and Zea mays L. polyamine oxidase: a comparative study.

Journal of enzyme inhibition 20010101

Continuous regional arterial infusion (CRAI) therapy reduces the mortality rate of acute necrotizing pancreatitis: results of a cooperative survey in Japan.

Journal of hepato-biliary-pancreatic surgery 20010101

Gabexate mesilate in acute pancreatitis: neither a miracle nor a mirage, merely the search of optimal dosage.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20010101

Acceleration of ulcer healing by cholecystokinin (CCK): role of CCK-A receptors, somatostatin, nitric oxide and sensory nerves.

Regulatory peptides 19990630

Gabexate mesylate inhibition of serine proteases: thermodynamic and computer-graphics analysis.

Journal of pharmaceutical sciences 19861201

Synthetic inhibitors of trypsin, plasmin, kallikrein, thrombin, C1r-, and C1 esterase.

Biochimica et biophysica acta 19771013