Home Halogens Cyclohexane, 1,2-dibromo-4-(1,2-dibromoethyl)-

Cyclohexane, 1,2-dibromo-4-(1,2-dibromoethyl)-

CAS No.:
3322-93-8
Catalog Number:
AG00I6H4
Molecular Formula:
C8H12Br4
Molecular Weight:
427.7969
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Product Description
Catalog Number:
AG00I6H4
Chemical Name:
Cyclohexane, 1,2-dibromo-4-(1,2-dibromoethyl)-
CAS Number:
3322-93-8
Molecular Formula:
C8H12Br4
Molecular Weight:
427.7969
MDL Number:
MFCD00086864
IUPAC Name:
1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane
InChI:
InChI=1S/C8H12Br4/c9-4-8(12)5-1-2-6(10)7(11)3-5/h5-8H,1-4H2
InChI Key:
PQRRSJBLKOPVJV-UHFFFAOYSA-N
SMILES:
BrCC(C1CCC(C(C1)Br)Br)Br
EC Number:
222-036-8
Properties
Complexity:
139  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
427.763g/mol
Formal Charge:
0
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
0
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
427.8g/mol
Monoisotopic Mass:
423.767g/mol
Rotatable Bond Count:
2  
Topological Polar Surface Area:
0A^2
Undefined Atom Stereocenter Count:
4  
Undefined Bond Stereocenter Count:
0
XLogP3:
4.6  
Literature
Title Journal
Toxicologic effects of 28-day dietary exposure to the flame retardant 1,2-dibromo-4-(1,2-dibromoethyl)-cyclohexane (TBECH) in F344 rats. Toxicology 20170215
TBECH, 1,2-dibromo-4-(1,2 dibromoethyl) cyclohexane, alters androgen receptor regulation in response to mutations associated with prostate cancer. Toxicology and applied pharmacology 20160915
The Effects of the Organic Flame-Retardant 1,2-Dibromo-4-(1,2-dibromoethyl) Cyclohexane (TBECH) on Androgen Signaling in Human Prostate Cancer Cell Lines. Journal of biochemical and molecular toxicology 20160501
Use of a Novel Double-Crested Cormorant ToxChip PCR Array and the EROD Assay to Determine Effects of Environmental Contaminants in Primary Hepatocytes. Environmental science & technology 20160315
1,2-Dibromo-4-(1,2-dibromoethyl)-cyclohexane and tris(methylphenyl) phosphate cause significant effects on development, mRNA expression, and circulating bile acid concentrations in chicken embryos. Toxicology and applied pharmacology 20140615
1,2-Dibromo-4-(1,2 dibromoethyl) cyclohexane (TBECH)-mediated steroid hormone receptor activation and gene regulation in chicken LMH cells. Environmental toxicology and chemistry 20140401
Use of an avian hepatocyte assay and the avian Toxchip Polymerse chain reaction array for testing prioritization of 16 organic flame retardants. Environmental toxicology and chemistry 20140301
The brominated flame retardant TBECH activates the zebrafish (Danio rerio) androgen receptor, alters gene transcription and causes developmental disturbances. Aquatic toxicology (Amsterdam, Netherlands) 20131015
Alpha and beta isomers of tetrabromoethylcyclohexane (TBECH) flame retardant: depletion and metabolite formation in vitro using a model rat microsomal assay. Environmental science & technology 20120918
Emerging brominated flame retardants in the sediment of the Great Lakes. Environmental science & technology 20120320
Liquid chromatography/tandem mass spectrometry for analysis of 1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane (TBECH) and 1,2,5,6-tetrabromocyclooctane (TBCO). Rapid communications in mass spectrometry : RCM 20110215
Toxicokinetics of tetrabromoethylcyclohexane (TBECH) in juvenile brown trout (Salmo trutta) and effects on plasma sex hormones. Aquatic toxicology (Amsterdam, Netherlands) 20110125
Accumulation of polybrominated diphenyl ethers, hexabromobenzene, and 1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane in earthworm (Eisenia fetida). Effects of soil type and aging. Environmental science & technology 20101201
Brominated flame retardants in the Arctic environment--trends and new candidates. The Science of the total environment 20100701
Biodegradation kinetics of selected brominated flame retardants in aerobic and anaerobic soil. Environmental pollution (Barking, Essex : 1987) 20100601
Diastereomers of the brominated flame retardant 1,2-dibromo-4-(1,2 dibromoethyl)cyclohexane induce androgen receptor activation in the hepg2 hepatocellular carcinoma cell line and the lncap prostate cancer cell line. Environmental health perspectives 20091201
Uptake and biotransformation of structurally diverse brominated flame retardants in zebrafish (Danio rerio) after dietary exposure. Environmental toxicology and chemistry 20090501
Temporal trends and spatial distribution of non-polybrominated diphenyl ether flame retardants in the eggs of colonial populations of Great Lakes herring gulls. Environmental science & technology 20090115
In vitro biologic activities of the antimicrobials triclocarban, its analogs, and triclosan in bioassay screens: receptor-based bioassay screens. Environmental health perspectives 20080901
Structure characterization and thermal stabilities of the isomers of the brominated flame retardant 1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane. Chemosphere 20080701
Identilication of the novel cycloaliphatic brominated flame retardant 1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane in Canadian Arctic beluga (Delphinapterus leucas). Environmental science & technology 20080115
Identification of the brominated flame retardant 1,2-dibromo-4-(1,2-dibromoethyl)cyclohexane as an androgen agonist. Journal of medicinal chemistry 20061214
Microsphere-based protease assays and screening application for lethal factor and factor Xa. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501
Properties