Home Sulfos 1-[2-(ethanesulfonyl)ethyl]-2-methyl-5-nitro-1H-imidazole

1-[2-(ethanesulfonyl)ethyl]-2-methyl-5-nitro-1H-imidazole

CAS No.:
19387-91-8
Catalog Number:
AG00I31A
Molecular Formula:
C8H13N3O4S
Molecular Weight:
247.2715
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
97%
In Stock USA
United States
$13
- +
25g
97%
In Stock USA
United States
$25
- +
100g
97%
In Stock USA
United States
$75
- +
500g
97%
In Stock USA
United States
$250
- +
Product Description
Catalog Number:
AG00I31A
Chemical Name:
1-[2-(ethanesulfonyl)ethyl]-2-methyl-5-nitro-1H-imidazole
CAS Number:
19387-91-8
Molecular Formula:
C8H13N3O4S
Molecular Weight:
247.2715
MDL Number:
MFCD00057217
IUPAC Name:
1-(2-ethylsulfonylethyl)-2-methyl-5-nitroimidazole
InChI:
InChI=1S/C8H13N3O4S/c1-3-16(14,15)5-4-10-7(2)9-6-8(10)11(12)13/h6H,3-5H2,1-2H3
InChI Key:
HJLSLZFTEKNLFI-UHFFFAOYSA-N
SMILES:
CCS(=O)(=O)CCn1c(C)ncc1[N+](=O)[O-]
EC Number:
243-014-4
UNII:
033KF7V46H
NSC Number:
758189
Properties
Complexity:
345  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
247.063g/mol
Formal Charge:
0
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
0
Isotope Atom Count:
0
Molecular Weight:
247.269g/mol
Monoisotopic Mass:
247.063g/mol
Rotatable Bond Count:
4  
Topological Polar Surface Area:
106A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-0.4  
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Bioequivalence evaluation of two different tablet formulations of tinidazole in healthy volunteers. Arzneimittel-Forschung 20080101
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The concept of personal drugs in the undergraduate pharmacology practical curriculum. Indian journal of pharmacology 20080101
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Analysis of bulk sample of salicylic Acid by application of hydrotropic solubilization method. Indian journal of pharmaceutical sciences 20080101
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A new quantitative in vitro microculture method for Giardia duodenalis trophozoites. Journal of microbiological methods 20071101
Clinical trial: knowledge of negative Helicobacter pylori status reduces subsequent dyspepsia-related resource use. Alimentary pharmacology & therapeutics 20071101
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[Treatment for Helicobacter pylori: current criteria]. Recenti progressi in medicina 20071101
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Short-term therapy for mixed vaginal infections. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20060201
Effect of probiotics and triple eradication therapy on the cyclooxygenase (COX)-2 expression, apoptosis, and functional gastric mucosal impairment in Helicobacter pylori-infected Mongolian gerbils. Helicobacter 20060201
Prevalence and treatment of Helicobacter pylori in patients with blepharitis. Investigative ophthalmology & visual science 20060201
Trichomoniasis and its treatment. Expert review of anti-infective therapy 20060201
Helicobacter pylori eradication with either 7-day or 10-day triple therapies, and with a 10-day sequential regimen. Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20060201
Clarithromycin-resistant genotypes and eradication of Helicobacter pylori. Annals of internal medicine 20060117
A study of 4- and 7-day triple therapy with rabeprazole, high-dose levofloxacin and tinidazole rescue treatment for Helicobacter pylori eradication. Alimentary pharmacology & therapeutics 20060115
Decreased susceptibility to nitroimidazoles among Bacteroides species in Brazil. Current microbiology 20060101
Efficacy of ronidazole for treatment of feline Tritrichomonas foetus infection. Journal of veterinary internal medicine 20060101
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[General malaise and diarrhea as the main manifestations of Giardia lamblia infection]. Gastroenterologia y hepatologia 20051101
Improved efficacy of 10-Day sequential treatment for Helicobacter pylori eradication in children: a randomized trial. Gastroenterology 20051101
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Recurrent fixed drug eruption due to metronidazole elicited by patch test with tinidazole. Contact dermatitis 20050901
Quadruple therapy with lactoferrin for Helicobacter pylori eradication: a randomised, multicentre study. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20050701
Management of metronidazole-resistant Trichomonas vaginalis--a new approach. International journal of STD & AIDS 20050701
High rate of Helicobacter pylori eradication with sequential therapy in elderly patients with peptic ulcer: a prospective controlled study. Alimentary pharmacology & therapeutics 20050615
[Dynamic release of tinidazole from the degradable PLLA-tinidazole blend gel]. Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20050601
Moxifloxacin-based strategies for first-line treatment of Helicobacter pylori infection. Alimentary pharmacology & therapeutics 20050515
Impact of treatment for bacterial vaginosis on prematurity among Brazilian pregnant women: a retrospective cohort study. Sao Paulo medical journal = Revista paulista de medicina 20050502
Twice-daily standard dose of omeprazole achieves the necessary level of acid inhibition for Helicobacter pylori eradication. A randomized controlled trial using standard and double doses of omeprazole in triple therapy. Digestive diseases and sciences 20050301
Probing NMR parameters, structure and dynamics of 5-nitroimidazole derivatives. Density functional study of prototypical radiosensitizers. Magnetic resonance in chemistry : MRC 20050201
Chronic Lyme borreliosis at the root of multiple sclerosis--is a cure with antibiotics attainable? Medical hypotheses 20050101
Rifabutin based triple therapy for eradication of H. pylori primary and secondary resistant to tinidazole and clarithromycin. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20050101
One-week versus two-week H2-receptor antagonist in combination with amoxicillin and tinidazole for eradication of Helicobacter pylori infection. Hepato-gastroenterology 20050101
[Clinical efficacy of a novel antimicrobial drug combination containing ciprofloxacin and tinidazole in the treatment of patients with skin and soft tissue infections]. Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic] 20050101
Anaphylaxis and hypersensitivity syndrome reactions in increasing severity following repeated exposure to tinidazole. Journal of postgraduate medicine 20050101
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Effect of Lactobacillus casei supplementation on the effectiveness and tolerability of a new second-line 10-day quadruple therapy after failure of a first attempt to cure Helicobacter pylori infection. Medical science monitor : international medical journal of experimental and clinical research 20041201
Comparison of one week and two weeks of triple therapy for the eradication of Helicobacter pylori in a Sri Lankan population: a randomised, controlled study. The Ceylon medical journal 20041201
Treatment of recurrent bacterial vaginosis with tinidazole. Obstetrics and gynecology 20041101
Lewis and Secretor status and Helicobacter pylori eradication. Epidemiology and infection 20041001
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Tinidazole (Tindamax) - a new anti-protozoal drug. The Medical letter on drugs and therapeutics 20040830
Dual vs. triple therapy for childhood Helicobacter pylori gastritis: a double-blind randomized multicentre trial. Helicobacter 20040801
Helicobacter pylori eradication in children and adolescents by a once daily 6-day treatment with or without a proton pump inhibitor in a double-blind randomized trial. Alimentary pharmacology & therapeutics 20040801
A predictive model for the release of slightly water-soluble drugs from HPMC matrices. Die Pharmazie 20040801
New drugs and dosage forms. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040715
The importance of the level of metronidazole resistance for the success of Helicobacter pylori eradication. Alimentary pharmacology & therapeutics 20040615
Use of imidazole-based eradication regimens for Helicobacter pylori should be abandoned in North India regardless of in vitro antibiotic sensitivity. Journal of gastroenterology and hepatology 20040601
Treatment of metronidazole-resistant Trichomonas vaginalis with tinidazole: case reports of three patients. Sexually transmitted diseases 20040601
Effect of antibacterial therapy and salivary secretion on the efficacy of Helicobacter pylori eradication in duodenal ulcer patients. Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 20040601
An in vitro study of the susceptibility of mobile and cystic forms of Borrelia burgdorferi to tinidazole. International microbiology : the official journal of the Spanish Society for Microbiology 20040601
[Effect of tinidazole-dexamethasone-iodoform paste on controlling endodontic interappointment emergencies]. Shanghai kou qiang yi xue = Shanghai journal of stomatology 20040601
[New drugs for the treatment of human parasitic protozoa]. Parassitologia 20040601
The efficacy of some drugs with known antiprotozoal activity against Histomonas meleagridis in chickens. Veterinary parasitology 20040526
Effectiveness and pharmaceutical cost of sequential treatment for Helicobacter pylori in patients with non-ulcer dyspepsia. Alimentary pharmacology & therapeutics 20040501
Voltammetric determination of tinidazole using a glassy carbon electrode modified with single-wall carbon nanotubes. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20040501
The prolongation of triple therapy for Helicobacter pylori does not allow reaching therapeutic outcome of sequential scheme: a prospective, randomised study. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20040501
Rank order of success favors longer duration of imidazole-based therapy for Helicobacter pylori in duodenal ulcer disease: a randomized pilot study. Helicobacter 20040401
Helicobacter pylori eradication: efficacy of conventional therapy in India. Tropical doctor 20040401
[Non-equilibrium properties of drug permeation through stratum corneum in vitro]. Yao xue xue bao = Acta pharmaceutica Sinica 20040401
[Dientamoeba fragilis: possibly an important cause of persistent abdominal pain in children]. Nederlands tijdschrift voor geneeskunde 20040320
Sequential treatment for Helicobacter pylori does not share the risk factors of triple therapy failure. Alimentary pharmacology & therapeutics 20040215
HPLC and LC-MS studies on stress degradation behaviour of tinidazole and development of a validated specific stability-indicating HPLC assay method. Journal of pharmaceutical and biomedical analysis 20040127
In vitro activity of antiamoebic drugs against clinical isolates of Entamoeba histolytica and Entamoeba dispar. Annals of clinical microbiology and antimicrobials 20040101
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Quantitative description and model of molecule transport through skin. Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 20040101
Intestinal parasitic infection and total serum IgG in asymptomatic adult males in an urban slum and efficacy of antiparasitic therapy. Indian journal of medical microbiology 20040101
Oral tinidazole treatment during pregnancy and teratogenesis. International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics 20031201
Ciprofloxacin-tinidazole combination, fluconazole- azithromicin-secnidazole-kit and doxycycline- metronidazole combination therapy in syndromic management of pelvic inflammatory disease: a prospective randomized controlled trial. Indian journal of medical sciences 20031201
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Randomized study of different 'second-line' therapies for Helicobacter pylori infection after failure of the standard 'Maastricht triple therapy'. Alimentary pharmacology & therapeutics 20031015
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Lactoferrin: milking ulcers? Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20031001
Use of bovine lactoferrin for Helicobacter pylori eradication. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20031001
Effects of metronidazole and tinidazole on NTPDase1 and ecto-5'-nucleotidase from intact cells of Trichomonas vaginalis. FEMS microbiology letters 20030926
Levofloxacin-based triple therapy vs. quadruple therapy in second-line Helicobacter pylori treatment: a randomized trial. Alimentary pharmacology & therapeutics 20030915
Sequential treatment for Helicobacter pylori eradication in duodenal ulcer patients: improving the cost of pharmacotherapy. Alimentary pharmacology & therapeutics 20030915
Identification of human cytochrome P(450)s that metabolise anti-parasitic drugs and predictions of in vivo drug hepatic clearance from in vitro data. European journal of clinical pharmacology 20030901
Comparative study on the effects of ointments of tinidazole, hydrocortisone and clobetasol on animal models for inflammatory dermatitis in mice. Fukuoka igaku zasshi = Hukuoka acta medica 20030901
Primary and secondary antibiotic resistance of Helicobacter pylori strains isolated in central Italy during the years 1998-2002. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20030801
Rabeprazole in a one-week eradication therapy of Helicobacter pylori: comparison of different dosages. Journal of gastroenterology and hepatology 20030701
Efficacy of the combination of 2 g oral tinidazole and acidic buffering vaginal gel in comparison with vaginal clindamycin alone in bacterial vaginosis: a randomized, investigator-blinded, controlled trial. European journal of obstetrics, gynecology, and reproductive biology 20030701
Helicobacter pylori eradication and peptic ulcer healing: the impact of deleting the proton pump inhibitor and using a once-daily treatment. Alimentary pharmacology & therapeutics 20030701
A novel pH- and time-dependent system for colonic drug delivery. Drug development and industrial pharmacy 20030701
[Failure of Helicobacter pylori eradication--suggestions for further therapy]. Orvosi hetilap 20030629
Late recurrence of resistant Trichomonas vaginalis vaginitis: relapse or re-infection? Sexually transmitted infections 20030601
Nitroheterocyclic drugs with broad spectrum activity. Parasitology research 20030601
Comparison of chloroquine, albendazole and tinidazole in the treatment of children with giardiasis. Annals of tropical medicine and parasitology 20030601
[Oleyl pyroglutamate for use as transdermal enhancer and its enhancing mechanism]. Yao xue xue bao = Acta pharmaceutica Sinica 20030501
Efficacy and tolerability of a combination of ofloxacin and tinidazole in the management of infectious diabetic foot ulcer. Journal of the Indian Medical Association 20030501
Omeprazole plus azithromycin and either amoxicillin or tinidazole for eradication of Helicobacter pylori infection. Journal of clinical gastroenterology 20030401
On the hydrolytic behavior of tinidazole, metronidazole, and ornidazole. Journal of pharmaceutical sciences 20030401
Two stability-indicating UV spectrophotometric methods for the analysis of hydrolyzed tinidazole. Journal of pharmaceutical and biomedical analysis 20030310
Effects of metronidazole and tinidazole ointments on models for inflammatory dermatitis in mice. Archives of dermatological research 20030301
High eradication rates of Helicobacter pylori with a new sequential treatment. Alimentary pharmacology & therapeutics 20030301
Triple eradication therapy counteracts functional impairment associated with Helicobacter pylori infection in Mongolian gerbils. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20030301
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[Antiprotozoal drugs]. Nihon rinsho. Japanese journal of clinical medicine 20030201
[The clinical evaluation of tinidazole-iodoform root canal paste on treatment of chronic periapical periodontitis associated with ectopic sinus]. Shanghai kou qiang yi xue = Shanghai journal of stomatology 20030201
[The state of immune system and effects of current therapy and immunomodulators]. Klinicheskaia meditsina 20030101
Use of lactoferrin for Helicobacter pylori eradication. Preliminary results. Journal of clinical gastroenterology 20030101
Triple therapy for 7 days vs. triple therapy for 7 days plus omeprazole for 21 days in treatment of active duodenal ulcer with Helicobacter pylori infection. A double blind placebo controlled trial. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20030101
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Serum mineral levels in children with intestinal parasitic infection. Digestive diseases (Basel, Switzerland) 20030101
One-week low-dose triple therapy without anti-acid treatment has sufficient efficacy on Helicobacter pylori eradication and ulcer healing. Hepato-gastroenterology 20030101
Pharmacokinetic evaluation of guar gum-based colon-targeted drug delivery systems of tinidazole in healthy human volunteers. Drug delivery 20030101
[Usefulness of 2 coproparasitological methods and their utilization in an antigiardiasis therapeutic trial]. Revista cubana de medicina tropical 20030101
Levofloxacin based regimens for the eradication of Helicobacter pylori. European journal of gastroenterology & hepatology 20021201
Design and in vitro evaluation of oral colon targeted drug delivery systems for tinidazole. Journal of drug targeting 20021201
Single-dose therapy for giardiasis in school-age children. The Southeast Asian journal of tropical medicine and public health 20021201
Effect of different probiotic preparations on anti-helicobacter pylori therapy-related side effects: a parallel group, triple blind, placebo-controlled study. The American journal of gastroenterology 20021101
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[Double blind randomized multicentre study of a seven-day eradication regime of Helicobacter pylori by omeprazole, clarithromycin and ornidazole vs. omeprazole, clarithromycin and metronidazole]. Vnitrni lekarstvi 20021001
In vitro activity of therapeutic drugs against Histomonas meleagridis (Smith, 1895). Poultry science 20020801
Validated HPLC method for the determination of tinidazole in human serum and its application in a clinical pharmacokinetic study. Die Pharmazie 20020801
DNA single strand breaks in peripheral blood lymphocytes induced by three nitroimidazole derivatives. Toxicology letters 20020614
Spectrophotometric determination of metronidazole and tinidazole in pharmaceutical preparations. Journal of pharmaceutical and biomedical analysis 20020515
Vitamin B12 and folic acid in children with intestinal parasitic infection. Journal of the American College of Nutrition 20020401
The cost-effectiveness of population Helicobacter pylori screening and treatment: a Markov model using economic data from a randomized controlled trial. Alimentary pharmacology & therapeutics 20020301
[Pharmacotherapeutic aspects of early postoperative period in patients with complicated gastroduodenal ulcer]. Klinichna khirurhiia 20020201
Efficacy of low-dose clarithromycin triple therapy and tinidazole-containing triple therapy for Helicobacter pylori eradication. Alimentary pharmacology & therapeutics 20020101
Gastric adenocarcinoma in a patient re-infected with H. pylori after regression of MALT lymphoma with successful anti-H. pylori therapy and gastric resection: a case report. BMC gastroenterology 20020101
Gateways to clinical trials. Methods and findings in experimental and clinical pharmacology 20020101
Recurrent isosporiasis over a decade in an immunocompetent host successfully treated with pyrimethamine. Scandinavian journal of infectious diseases 20020101
A simple and rapid liquid chromatographic method for the determination of metronidazole and its hydroxymetabolite in plasma and cutaneous microdialysates. Acta poloniae pharmaceutica 20020101
Efficacy of the triple therapy: proton pomp inhibitors, amoxicillin and tynidazole in Helicobacter pylori infection treatment. Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20020101
Helicobacter pylori eradication does not exacerbate reflux symptoms in gastroesophageal reflux disease. Gastroenterology 20011101
Two new treatment regimens for Helicobacter pylori eradication: a randomised study. Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20011101
Retrospective analysis of drug-induced urticaria and angioedema: a survey of 2287 patients. Immunopharmacology and immunotoxicology 20011101
Tinidazole therapy for metronidazole-resistant vaginal trichomoniasis. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20011015
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[Diarrhea due to a toxin of Clostridium difficile in hemato-oncological patients]. Nederlands tijdschrift voor geneeskunde 20010908
Remission of a high-grade gastric mucosa associated lymphoid tissue (MALT) lymphoma following Helicobacter pylori eradication and highly active antiretroviral therapy in a patient with AIDS. The American journal of medicine 20010901
Evaluation of diazotized 4-amino-3,5-dinitrobenzoic acid (ADBA) as a new derivatizing reagent. African journal of medicine and medical sciences 20010901
A triple therapy regimen after failed Helicobacter pylori treatments. Alimentary pharmacology & therapeutics 20010801
Famotidine versus omeprazole, in combination with amoxycillin and tinidazole, for eradication of Helicobacter pylori infection. European journal of gastroenterology & hepatology 20010801
Diagnostic advantages and therapeutic options for giardiasis. Expert opinion on investigational drugs 20010801
Ranitidine bismuth citrate-based triple therapies after failure of the standard 'Maastricht triple therapy': a promising alternative to the quadruple therapy? Alimentary pharmacology & therapeutics 20010701
Efficacy of a nitroimidazole containing tripletherapy regime in Singapore. Singapore medical journal 20010701
Evaluation of genetic damage induced by a nitroimidazole derivative in human lymphocytes: Tinidazole (TNZ). Toxicology in vitro : an international journal published in association with BIBRA 20010601
[Role of Helicobacter pylori infection in insulin-dependent diabetes mellitus]. Minerva medica 20010601
Lansoprazole-based triple therapy versus ranitidine bismuth citrate-based dual therapy in the eradication of Helicobacter pylori in patients with duodenal ulcer: a multicenter, randomized, double-dummy study. Clinical therapeutics 20010501
[Dental status and efficacy of Helicobacter pylori eradication]. Polskie Archiwum Medycyny Wewnetrznej 20010401
The effect of oral administration of Lactobacillus GG on antibiotic-associated gastrointestinal side-effects during Helicobacter pylori eradication therapy. Alimentary pharmacology & therapeutics 20010201
Prevalence of 5-nitroimidazole-resistant trichomonas vaginalis in Oviedo, Spain. Sexually transmitted diseases 20010201
[Study of bacteriology on local application of Tinidazole stilus in treatment for periodontitis]. Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20010201
Long-term follow-up and serologic assessment after triple therapy with omeprazole or lansoprazole of Helicobacter-associated duodenal ulcer. Journal of clinical gastroenterology 20010101
Effect of Lactobacillus GG supplementation on antibiotic-associated gastrointestinal side effects during Helicobacter pylori eradication therapy: a pilot study. Digestion 20010101
[In vitro measurement of nitazoxanide sensitivity of 4 Giardia duodenalis isolates obtained from different hosts]. Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20010101
Factors affecting Helicobacter pylori eradication using a seven-day triple therapy with a proton pump inhibitor, tinidazole and clarithromycin, in Brazilian patients with peptic ulcer. Revista do Hospital das Clinicas 20010101
Efficacy and tolerability of antibiotics in patients undergoing H. pylori eradication. Hepato-gastroenterology 20010101
Prevalence and characteristics of nim genes encoding 5-nitroimidazole resistance among Bacteroides strains isolated in Morocco. Microbial drug resistance (Larchmont, N.Y.) 20010101
Efficacy of Helicobacter pylori eradication therapies: a single centre observational study. BMC gastroenterology 20010101
Six regimens for the eradication of Helicobacter pylori (Hp) in duodenal ulcer patients: three consecutive trials (1995-1999). Journal of physiology, Paris 20010101
Guar gum as a carrier for colon specific delivery; influence of metronidazole and tinidazole on in vitro release of albendazole from guar gum matrix tablets. Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20010101
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The incidence of non ulcer dyspepsia and its response to treatment. Journal of Ayub Medical College, Abbottabad : JAMC 20010101
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