4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzene-1-sulfonamide
Title | Journal |
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COX-2 inhibition by celecoxib in epithelial ovarian cancer attenuates E-cadherin suppression through reduced Snail nuclear translocation. | Chemico-biological interactions 20180825 |
Discovery of new indomethacin-based analogs with potentially selective cyclooxygenase-2 inhibition and observed diminishing to PGE2 activities. | European journal of medicinal chemistry 20171201 |
Derivation and Evaluation of Putative Adverse Outcome Pathways for the Effects of Cyclooxygenase Inhibitors on Reproductive Processes in Female Fish. | Toxicological sciences : an official journal of the Society of Toxicology 20170401 |
Involvement of COX-2 in nickel elution from a wire implanted subcutaneously in mice. | Toxicology 20160701 |
Rational Design of Small Peptides for Optimal Inhibition of Cyclooxygenase-2: Development of a Highly Effective Anti-Inflammatory Agent. | Journal of medicinal chemistry 20160428 |
The Role of Prostaglandins and COX-Enzymes in Chondrogenic Differentiation of ATDC5 Progenitor Cells. | PloS one 20160101 |
Taurocholate Induces Cyclooxygenase-2 Expression via the Sphingosine 1-phosphate Receptor 2 in a Human Cholangiocarcinoma Cell Line. | The Journal of biological chemistry 20151225 |
Celecoxib increases lung cancer cell lysis by lymphokine-activated killer cells via upregulation of ICAM-1. | Oncotarget 20151117 |
Towards a systematic analysis of human short-chain dehydrogenases/reductases (SDR): Ligand identification and structure-activity relationships. | Chemico-biological interactions 20150605 |
Systems pharmacological analysis of drugs inducing stevens-johnson syndrome and toxic epidermal necrolysis. | Chemical research in toxicology 20150518 |
Celecoxib, but not indomethacin, ameliorates the hypertensive and perivascular fibrotic actions of cyclosporine in rats: role of endothelin signaling. | Toxicology and applied pharmacology 20150401 |
The superoxide anion donor, potassium superoxide, induces pain and inflammation in mice through production of reactive oxygen species and cyclooxygenase-2. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20150401 |
MAPK pathway activation by chronic lead-exposure increases vascular reactivity through oxidative stress/cyclooxygenase-2-dependent pathways. | Toxicology and applied pharmacology 20150301 |
Arsenic sulfide combined with JQ1, chemotherapy agents, or celecoxib inhibit gastric and colon cancer cell growth. | Drug design, development and therapy 20150101 |
Effects of conventional and hydrogen sulfide-releasing non-steroidal anti-inflammatory drugs in rats with stress-induced and epinephrine-induced gastric damage. | Stress (Amsterdam, Netherlands) 20141201 |
Chrysin alleviates testicular dysfunction in adjuvant arthritic rats via suppression of inflammation and apoptosis: comparison with celecoxib. | Toxicology and applied pharmacology 20140901 |
Remedial effects of novel 2,3-disubstituted thiazolidin-4-ones in chemical mediated inflammation. | Chemico-biological interactions 20140305 |
Celecoxib offsets the negative renal influences of cyclosporine via modulation of the TGF-β1/IL-2/COX-2/endothelin ET(B) receptor cascade. | Toxicology and applied pharmacology 20140301 |
Acute exposure to lead acetate activates microglia and induces subsequent bystander neuronal death via caspase-3 activation. | Neurotoxicology 20140301 |
A correlation between the in vitro drug toxicity of drugs to cell lines that express human P450s and their propensity to cause liver injury in humans. | Toxicological sciences : an official journal of the Society of Toxicology 20140101 |
Assessing the cardiovascular risk between celecoxib and nonselective nonsteroidal antiinflammatory drugs in patients with rheumatoid arthritis and osteoarthritis. | Circulation journal : official journal of the Japanese Circulation Society 20140101 |
IL-6-mediated induction of matrix metalloproteinase-9 is modulated by JAK-dependent IL-10 expression in macrophages. | Journal of immunology (Baltimore, Md. : 1950) 20140101 |
Comparison of the efficacy and safety profiles of a pelubiprofen versus celecoxib in patients with rheumatoid arthritis: a 6-week, multicenter, randomized, double-blind, phase III, non-inferiority clinical trial. | BMC musculoskeletal disorders 20140101 |
Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11). | Toxicological sciences : an official journal of the Society of Toxicology 20131201 |
Induction but not inhibition of COX-2 confers human lung cancer cell apoptosis by celecoxib. | Journal of lipid research 20131101 |
Small molecule activators of the Nrf2-HO-1 antioxidant axis modulate heme metabolism and inflammation in BV2 microglia cells. | Pharmacological research 20131001 |
Carbonic anhydrase inhibitors: synthesis and inhibition of the human carbonic anhydrase isoforms I, II, VII, IX and XII with benzene sulfonamides incorporating 4,5,6,7-tetrabromophthalimide moiety. | Bioorganic & medicinal chemistry 20131001 |
Identification of potent Yes1 kinase inhibitors using a library screening approach. | Bioorganic & medicinal chemistry letters 20130801 |
Mercury induces proliferation and reduces cell size in vascular smooth muscle cells through MAPK, oxidative stress and cyclooxygenase-2 pathways. | Toxicology and applied pharmacology 20130415 |
Synthesis and characterization of celecoxib derivatives as possible anti-inflammatory, analgesic, antioxidant, anticancer and anti-HCV agents. | Molecules (Basel, Switzerland) 20130321 |
An emerging role for anti-inflammatory agents for chemoprevention. | Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20130101 |
COX-2 active agents in the chemoprevention of colorectal cancer. | Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer 20130101 |
Indomethacin-enhanced anticancer effect of arsenic trioxide in A549 cell line: involvement of apoptosis and phospho-ERK and p38 MAPK pathways. | BioMed research international 20130101 |
Involvement of hypothalamic cyclooxygenase-2, interleukin-1β and melanocortin in the development of docetaxel-induced anorexia in rats. | Toxicology 20121216 |
Effect of celecoxib add-on treatment on symptoms and serum IL-6 concentrations in patients with major depressive disorder: randomized double-blind placebo-controlled study. | Journal of affective disorders 20121210 |
Transgenic insulin-like growth factor-1 stimulates activation of COX-2 signaling in mammary glands. | Molecular carcinogenesis 20121201 |
Preferential killing of triple-negative breast cancer cells in vitro and in vivo when pharmacological aggravators of endoplasmic reticulum stress are combined with autophagy inhibitors. | Cancer letters 20121201 |
Synthesis, biological evaluation and molecular modeling of dihydro-pyrazolyl-thiazolinone derivatives as potential COX-2 inhibitors. | Bioorganic & medicinal chemistry 20121115 |
Effects of celecoxib on restenosis after coronary intervention and evolution of atherosclerosis (Mini-COREA) trial: celecoxib, a double-edged sword for patients with angina. | European heart journal 20121101 |
Dolastatin 15, a mollusk linear peptide, and Celecoxib, a selective cyclooxygenase-2 inhibitor, prevent preneoplastic colonic lesions and induce apoptosis through inhibition of the regulatory transcription factor NF-κB and an inflammatory protein, iNOS. | European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20121101 |
Renal effects of high-dose celecoxib in elderly men with stage D2 prostate carcinoma. | Clinical nephrology 20121101 |
Involvement of PGE2 and RANTES in Staphylococcus aureus-induced fever in rats. | Journal of applied physiology (Bethesda, Md. : 1985) 20121101 |
Synthesis and pharmacological evaluation of N-substituted 2-(2-oxo-2H-chromen-4-yloxy)propanamide as cyclooxygenase inhibitors. | Bioorganic & medicinal chemistry letters 20121101 |
Celecoxib desensitization: continued temozolomide/celecoxib chemotherapy after a celecoxib-induced hypersensitivity reaction. | Anti-cancer drugs 20121101 |
Novel 3-substituted-1-aryl-5-phenyl-6-anilinopyrazolo[3,4-d]pyrimidin-4-ones: docking, synthesis and pharmacological evaluation as a potential anti-inflammatory agents. | Bioorganic & medicinal chemistry letters 20121101 |
AEE788 potentiates celecoxib-induced growth inhibition and apoptosis in human colon cancer cells. | Life sciences 20121022 |
Silymarin potentiates the anti-inflammatory effects of Celecoxib on chemically induced osteoarthritis in rats. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20121015 |
WIN-34B, a new herbal medicine, inhibits the inflammatory response by inactivating IκB-α phosphorylation and mitogen activated protein kinase pathways in fibroblast-like synoviocytes. | Journal of ethnopharmacology 20121011 |
Release profile and characteristics of electrosprayed particles for oral delivery of a practically insoluble drug. | Journal of the Royal Society, Interface 20121007 |
Celecoxib inactivates epithelial-mesenchymal transition stimulated by hypoxia and/or epidermal growth factor in colon cancer cells. | Molecular carcinogenesis 20121001 |
Effect of celecoxib on Ca(2+) handling and viability in human prostate cancer cells (PC3). | Drug and chemical toxicology 20121001 |
Metastatic melanoma patients treated with dendritic cell vaccination, Interleukin-2 and metronomic cyclophosphamide: results from a phase II trial. | Cancer immunology, immunotherapy : CII 20121001 |
Non-selective inhibition of cyclooxygenase enzymes by aminoacetylenic isoindoline 1,3-diones. | Inflammation & allergy drug targets 20121001 |
Use of reduced-dose periarticular injection for pain management in simultaneous bilateral total knee arthroplasty. | The Journal of arthroplasty 20121001 |
Celecoxib enhances the anti-inflammatory effects of farnesylthiosalicylic acid on T cells independent of prostaglandin E(2) production. | Inflammation 20121001 |
Celecoxib enhances the effect of reboxetine and fluoxetine on cortical noradrenaline and serotonin output in the rat. | Progress in neuro-psychopharmacology & biological psychiatry 20121001 |
Cell intrinsic role of COX-2 in pancreatic cancer development. | Molecular cancer therapeutics 20121001 |
Celecoxib delays cognitive decline in an animal model of neurodegeneration. | Behavioural brain research 20121001 |
Colorectal polyps in childhood. | Current opinion in pediatrics 20121001 |
The developing Xenopus limb as a model for studies on the balance between inflammation and regeneration. | Anatomical record (Hoboken, N.J. : 2007) 20121001 |
Potent and orally efficacious benzothiazole amides as TRPV1 antagonists. | Bioorganic & medicinal chemistry letters 20121001 |
Reactivity of nonsteroidal anti-inflammatory drugs with peroxidase: a classification of nonsteroidal anti-inflammatory drugs. | The Journal of pharmacy and pharmacology 20121001 |
Cyclooxygenase-2 inhibition for the prevention of subglottic stenosis. | Archives of otolaryngology--head & neck surgery 20121001 |
[Effects of COX-2 inhibitor celecoxib on expressions of VEGF, b-FGF and TGF-β mRNA in acute leukemia cells]. | Zhongguo shi yan xue ye xue za zhi 20121001 |
Cyclooxygenase-2 inhibitors modulate skin aging in a catalytic activity-independent manner. | Experimental & molecular medicine 20120930 |
Phospholipase A₂ activities in skin physiology and pathology. | European journal of pharmacology 20120915 |
Inhibition of cyclooxygenase-2 causes regression of gastric adenomas in trefoil factor 1 deficient mice. | International journal of cancer 20120901 |
Antiangiogenic metronomic therapy for children with recurrent embryonal brain tumors. | Pediatric blood & cancer 20120901 |
The novel NF-κB inhibitor DHMEQ synergizes with celecoxib to exert antitumor effects on human liver cancer cells by a ROS-dependent mechanism. | Cancer letters 20120901 |
The use of different analgesics in orthodontic tooth movements. | The Angle orthodontist 20120901 |
A patient with Leiden V mutation, multiple sclerosis, psoriasis, and sicca syndrome: could celecoxib and fingolimod adversely affect the heart? | Cardiovascular toxicology 20120901 |
Dermal microdialysis technique to evaluate the trafficking of surface-modified lipid nanoparticles upon topical application. | Pharmaceutical research 20120901 |
Production and actions of the anandamide metabolite prostamide E2 in the renal medulla. | The Journal of pharmacology and experimental therapeutics 20120901 |
Antitumor and anti-metastatic effects of cyclooxygenase-2 inhibition by celecoxib on human colorectal carcinoma xenografts in nude mouse rectum. | Oncology reports 20120901 |
Risk factors associated with a decrease ≥2 g/dL in haemoglobin and/or ≥10% haematocrit in osteoarthritis patients taking celecoxib or a nonselective NSAID plus a PPI in a large randomised controlled trial (CONDOR). | Alimentary pharmacology & therapeutics 20120901 |
New pyrimido[5,4-e]pyrrolo[1,2-c]pyrimidines: synthesis, 2D-QSAR, anti-inflammatory, analgesic and ulcerogenicity studies. | European journal of medicinal chemistry 20120901 |
Acute Ibuprofen intoxication: report on a case and review of the literature. | The American journal of forensic medicine and pathology 20120901 |
Efficacy and safety of celecoxib versus diclofenac and omeprazole in elderly arthritis patients: a subgroup analysis of the CONDOR trial. | Current medical research and opinion 20120901 |
Efficacy and tolerability of celecoxib in the treatment of acute gouty arthritis: a randomized controlled trial. | The Journal of rheumatology 20120901 |
Safety of nonsteroidal antiinflammatory drugs and/or paracetamol in people receiving methotrexate for inflammatory arthritis: a Cochrane systematic review. | The Journal of rheumatology. Supplement 20120901 |
Use of dynamic weight bearing as a novel end-point for the assessment of Freund's Complete Adjuvant induced hypersensitivity in mice. | Neuroscience letters 20120830 |
In vitro approach to assess the potential for risk of idiosyncratic adverse reactions caused by candidate drugs. | Chemical research in toxicology 20120820 |
Predicting new indications for approved drugs using a proteochemometric method. | Journal of medicinal chemistry 20120809 |
Apricoxib upregulates 15-PGDH and PGT in tobacco-related epithelial malignancies. | British journal of cancer 20120807 |
The effects of NSAIDs on types I, II, and III collagen metabolism in a rat osteoarthritis model. | Rheumatology international 20120801 |
Dosing celecoxib in pediatric patients with juvenile rheumatoid arthritis. | Journal of clinical pharmacology 20120801 |
Cyclooxygenase-2 inhibitors and cardiovascular risk in a nation-wide cohort study after the withdrawal of rofecoxib. | European heart journal 20120801 |
Antiproliferative effects of selective cyclooxygenase-2 inhibitor modulated by nimotuzumab in estrogen-dependent breast cancer cells. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20120801 |
Combination of EGFR and COX-2 inhibitors in breast cancer patient. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20120801 |
Sustained-release celecoxib from incubated acrylic intraocular lenses suppresses lens epithelial cell growth in an ex vivo model of posterior capsule opacity. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20120801 |
Expression of selected genes in preterm premature rupture of fetal membranes. | Acta obstetricia et gynecologica Scandinavica 20120801 |
Targeting COX-2 and EP4 to control tumor growth, angiogenesis, lymphangiogenesis and metastasis to the lungs and lymph nodes in a breast cancer model. | Laboratory investigation; a journal of technical methods and pathology 20120801 |
Orally administered rubiscolin-6, a δ opioid peptide derived from Rubisco, stimulates food intake via leptomeningeal lipocallin-type prostaglandin D synthase in mice. | Molecular nutrition & food research 20120801 |
Efficient synthesis and 5-LOX/COX-inhibitory activity of some 3-hydroxybenzo[b]thiophene-2-carboxylic acid derivatives. | Bioorganic & medicinal chemistry letters 20120801 |
Development of novel antibacterial agents against methicillin-resistant Staphylococcus aureus. | Bioorganic & medicinal chemistry 20120801 |
Development of simple and rapid LC-MS/MS method for determination of celecoxib in human plasma and its application to bioequivalence study. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120801 |
Indole based cyclooxygenase inhibitors: synthesis, biological evaluation, docking and NMR screening. | European journal of medicinal chemistry 20120801 |
Reduction of DNA damage by curcumin and celecoxib in epithelial cell cultures of the oropharynx after incubation with tobacco smoke condensate. | Anticancer research 20120801 |
Association between COX-2 expression and effectiveness of COX-2 inhibitors in a phase II trial in patients with metastatic colorectal adenocarcinoma. | Anticancer research 20120801 |
Angiogenesis inhibition by green propolis and the angiogenic effect of L-lysine on bladder cancer in rats. | Acta cirurgica brasileira 20120801 |
Economic outcomes for celecoxib: a systematic review of pharmacoeconomic studies. | Expert review of pharmacoeconomics & outcomes research 20120801 |
Primary systemic therapy in HER2-amplified breast cancer: a clinical review. | Expert review of anticancer therapy 20120801 |
NSAIDs in orthodontic tooth movement. | Journal of pharmacy & bioallied sciences 20120801 |
The EP1 receptor for prostaglandin E2 promotes the development and progression of malignant murine skin tumors. | Molecular carcinogenesis 20120701 |
COX-2-independent induction of apoptosis by celecoxib and polyamine naphthalimide conjugate mediated by polyamine depression in colorectal cancer cell lines. | International journal of colorectal disease 20120701 |
Sensitivity of gait parameters to the effects of anti-inflammatory and opioid treatments in knee osteoarthritis patients. | Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20120701 |
Effect of selective and non-selective cyclooxygenase inhibitors on doxorubicin-induced cardiotoxicity and nephrotoxicity in rats. | Toxicology mechanisms and methods 20120701 |
Determination of non-steroidal anti-inflammatory drugs and their metabolites in milk by liquid chromatography-tandem mass spectrometry. | Analytical and bioanalytical chemistry 20120701 |
Role of Sulindac and Celecoxib in the regulation of angiogenesis during the early neoplasm of colon: exploring PI3-K/PTEN/Akt pathway to the canonical Wnt/β-catenin signaling. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20120701 |
Celecoxib inhibits growth of human autosomal dominant polycystic kidney cyst-lining epithelial cells through the VEGF/Raf/MAPK/ERK signaling pathway. | Molecular biology reports 20120701 |
Celecoxib enhances the radiosensitizing effect of 7-hydroxystaurosporine (UCN-01) in human lung cancer cell lines. | International journal of radiation oncology, biology, physics 20120701 |
Etodolac, a cyclooxygenase-2 inhibitor, attenuates paclitaxel-induced peripheral neuropathy in a mouse model of mechanical allodynia. | The Journal of pharmacology and experimental therapeutics 20120701 |
Nonsteroidal anti-inflammatory drug-activated gene-1 plays a role in the impairing effects of cyclooxygenase inhibitors on gastric ulcer healing. | The Journal of pharmacology and experimental therapeutics 20120701 |
Dispensed selective and nonselective nonsteroidal anti-inflammatory drugs and the risk of moderate to severe hyperkalemia: a nested case-control study. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20120701 |
Cyclooxygenase-2 inhibitors induce anoikis in osteosarcoma via PI3K/Akt pathway. | Medical hypotheses 20120701 |
New quinazolinone-pyrimidine hybrids: synthesis, anti-inflammatory, and ulcerogenicity studies. | European journal of medicinal chemistry 20120701 |
Downregulation of Prominin 1/CD133 expression in colorectal cancer by NSAIDs following short-term preoperative treatment. | International journal of oncology 20120701 |
NSAIDs induce apoptosis in nonproliferating ovarian cancer cells and inhibit tumor growth in vivo. | IUBMB life 20120701 |
Ellagic acid facilitates indomethacin-induced gastric ulcer healing via COX-2 up-regulation. | Acta biochimica et biophysica Sinica 20120701 |
Colon-specific delivery of celecoxib is a potential strategy to improve toxicological and pharmacological properties of the selective Cox-2 inhibitor: implication in treatment of familiar adenomatous polyposis. | Journal of drug targeting 20120701 |
Sulfonamides: a patent review (2008 - 2012). | Expert opinion on therapeutic patents 20120701 |
Activation of mitochondrial apoptosis pathways in cutaneous squamous cell carcinoma cells by diclofenac/hyaluronic acid is related to upregulation of Bad as well as downregulation of Mcl-1 and Bcl-w. | Experimental dermatology 20120701 |
New therapeutic agents in uveal melanoma. | Anticancer research 20120701 |
The HMGA1-COX-2 axis: a key molecular pathway and potential target in pancreatic adenocarcinoma. | Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20120701 |
Inhibition of COX-2 in colon cancer modulates tumor growth and MDR-1 expression to enhance tumor regression in therapy-refractory cancers in vivo. | Neoplasia (New York, N.Y.) 20120701 |
Use of nonsteroidal anti-inflammatory drugs and risk of basal cell carcinoma in the United States Radiologic Technologists study. | International journal of cancer 20120615 |
Cyclooxygenase-2 prostaglandins mediate anandamide-inhibitory action on nitric oxide synthase activity in the receptive rat uterus. | European journal of pharmacology 20120615 |
Determination of celecoxib in human plasma by liquid chromatography-tandem mass spectrometry. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20120615 |
Synthesis and biological evaluation of derivatives of 2-{2-fluoro-4-[(2-oxocyclopentyl)methyl]phenyl}propanoic acid: nonsteroidal anti-inflammatory drugs with low gastric ulcerogenic activity. | Journal of medicinal chemistry 20120614 |
Development and characterization of a novel drug nanocarrier for oral delivery, based on self-assembled β-casein micelles. | Journal of controlled release : official journal of the Controlled Release Society 20120610 |
(-)-Epigallocatechin-3-gallate, a green tea-derived catechin, synergizes with celecoxib to inhibit IL-1-induced tumorigenic mediators by human pancreatic adenocarcinoma cells Colo357. | European journal of pharmacology 20120605 |
Celecoxib or naproxen treatment does not benefit depressive symptoms in persons age 70 and older: findings from a randomized controlled trial. | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20120601 |
Celecoxib, a cyclooxygenase-2 inhibitor, improved upper gastrointestinal lesions in rheumatoid arthritis patients as assessed by endoscopic evaluation. | Modern rheumatology 20120601 |
Effects of selective COX-2 inhibitor and Helicobacter pylori eradication on precancerous gastric lesions. | Gut 20120601 |
A turbulent decade for NSAIDs: update on current concepts of classification, epidemiology, comparative efficacy, and toxicity. | Rheumatology international 20120601 |
Effects of antidepressants and cyclooxygenase-2 inhibitor on cytokines and kynurenines in stimulated in vitro blood culture from depressed patients. | Inflammopharmacology 20120601 |
Comparative impact on prostanoid biosynthesis of celecoxib and the novel nonsteroidal anti-inflammatory drug CG100649. | Clinical pharmacology and therapeutics 20120601 |
N-Acetylglucosaminyltransferase V regulates TGF-β response in hepatic stellate cells and the progression of steatohepatitis. | Glycobiology 20120601 |
Adherence to routine use of pharmacological prophylaxis of heterotopic ossification after total hip arthroplasty: results from an Italian multicenter, prospective, observational survey. | Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology 20120601 |
Clinical, pharmacokinetic and pharmacodynamic evaluations of metronomic UFT and cyclophosphamide plus celecoxib in patients with advanced refractory gastrointestinal cancers. | Angiogenesis 20120601 |
Retrospective evaluation of inpatient celecoxib use after total hip and knee arthroplasty at a Veterans Affairs Medical Center. | The Journal of arthroplasty 20120601 |
Recent developments and biological activities of thiazolidinone derivatives: a review. | Bioorganic & medicinal chemistry 20120601 |
Gene expression profile of coronary artery cells treated with nonsteroidal anti-inflammatory drugs reveals off-target effects. | Journal of cardiovascular pharmacology 20120601 |
Celecoxib inhibits invasion and metastasis via a cyclooxygenase 2-independent mechanism in an in vitro model of Ewing sarcoma. | Journal of pediatric surgery 20120601 |
Dual function of tributyrin emulsion: solubilization and enhancement of anticancer effect of celecoxib. | International journal of pharmaceutics 20120530 |
Hybrid nanomaterials that mimic the food effect: controlling enzymatic digestion for enhanced oral drug absorption. | Angewandte Chemie (International ed. in English) 20120529 |
Prostate cancer: celecoxib trampled in the STAMPEDE trial. | Nature reviews. Urology 20120529 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions. | Journal of medicinal chemistry 20120524 |
Celecoxib, a cyclooxygenase-2 inhibitor, potentiates the chemotherapic effect of vinorelbine in the medullary thyroid cancer TT cell line. | Molecular and cellular endocrinology 20120515 |
Synthesis and biological activity of 2-aminothiazoles as novel inhibitors of PGE2 production in cells. | Bioorganic & medicinal chemistry letters 20120515 |
Synthesis, biological evaluation and molecular modeling study of pyrazole and pyrazoline derivatives as selective COX-2 inhibitors and anti-inflammatory agents. Part 2. | Bioorganic & medicinal chemistry 20120515 |
[Inflammation-induced pain. How rheumatism patients profit from the proper NSAID choice]. | MMW Fortschritte der Medizin 20120503 |
Vascular COX-2 modulates blood pressure and thrombosis in mice. | Science translational medicine 20120502 |
Inhibition of cyclooxygenase-2 modulates phenotypic switching of vascular smooth muscle cells during increased aortic blood flow. | Heart and vessels 20120501 |
The cyclooxygenase-2 pathway via the PGE₂ EP2 receptor contributes to oligodendrocytes apoptosis in cuprizone-induced demyelination. | Journal of neurochemistry 20120501 |
Celecoxib can prevent capecitabine-related hand-foot syndrome in stage II and III colorectal cancer patients: result of a single-center, prospective randomized phase III trial. | Annals of oncology : official journal of the European Society for Medical Oncology 20120501 |
Febrile response induced by cecal ligation and puncture (CLP) in rats: involvement of prostaglandin E2 and cytokines. | Medical microbiology and immunology 20120501 |
Non-steroidal anti-inflammatory drugs use and risk of upper gastrointestinal adverse events in cirrhotic patients. | Liver international : official journal of the International Association for the Study of the Liver 20120501 |
Chronic anti-inflammatory drug therapy inhibits gel-forming mucin production in a murine xenograft model of human pseudomyxoma peritonei. | Annals of surgical oncology 20120501 |
Chemopreventive efficacy of Targretin in rodent models of urinary bladder, colon/intestine, head and neck and mammary cancers. | Oncology reports 20120501 |
N-succinylaspart-1-yl celecoxib is a potential colon-specific prodrug of celecoxib with improved therapeutic properties. | Journal of pharmaceutical sciences 20120501 |
Lansoprazole for secondary prevention of gastric or duodenal ulcers associated with long-term non-steroidal anti-inflammatory drug (NSAID) therapy: results of a prospective, multicenter, double-blind, randomized, double-dummy, active-controlled trial. | Journal of gastroenterology 20120501 |
Cyclooxygenase-2 inhibition restores ultraviolet B-induced downregulation of ATP2A2/SERCA2 in keratinocytes: possible therapeutic approach of cyclooxygenase-2 inhibition for treatment of Darier disease. | The British journal of dermatology 20120501 |
The STAMPEDE trial and celecoxib: how to adapt? | The Lancet. Oncology 20120501 |
Celecoxib plus hormone therapy versus hormone therapy alone for hormone-sensitive prostate cancer: first results from the STAMPEDE multiarm, multistage, randomised controlled trial. | The Lancet. Oncology 20120501 |
Combination chemoprevention: future direction of colorectal cancer prevention. | European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20120501 |
Design and synthesis of 4-O-methylhonokiol analogs as inhibitors of cyclooxygenase-2 (COX-2) and PGF₁ production. | Bioorganic & medicinal chemistry 20120501 |
Celecoxib induces apoptosis and cell-cycle arrest in nasopharyngeal carcinoma cell lines via inhibition of STAT3 phosphorylation. | Acta pharmacologica Sinica 20120501 |
Schizophrenia and the immune system: pathophysiology, prevention, and treatment. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20120501 |
Inducible cyclooxygenase expression mediating hypoxia/reoxygenation-induced pulmonary vasoconstriction is attenuated by a cyclooxygenase inhibitor in rats. | Transplantation proceedings 20120501 |
Italian guidelines for primary headaches: 2012 revised version. | The journal of headache and pain 20120501 |
Synthesis of novel pyrazole and dihydropyrazoles derivatives as potential anti-inflammatory and analgesic agents. | Archives of pharmacal research 20120501 |
[An experimental study on chemoprevention of esophageal adenocarcinoma by celecoxib, a selective cyclooxygenase-2 inhibitor]. | Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery 20120501 |
[Serum levels of cartilage oligomeric matrix protein in the diagnosis of knee osteoarthritis]. | Zhongguo gu shang = China journal of orthopaedics and traumatology 20120501 |
[Inhibitory effects of cyclooxygenase-2 selective inhibitor Celecoxib on human nephroblastoma]. | Zhonghua bing li xue za zhi = Chinese journal of pathology 20120501 |
Structure-activity relationship of nonacidic quinazolinone inhibitors of human microsomal prostaglandin synthase 1 (mPGES 1). | Journal of medicinal chemistry 20120426 |
Protective role of adiponectin against ethanol-induced gastric injury in mice. | American journal of physiology. Gastrointestinal and liver physiology 20120415 |
Celecoxib and tauro-ursodeoxycholic acid co-treatment inhibits cell growth in familial adenomatous polyposis derived LT97 colon adenoma cells. | Experimental cell research 20120415 |
Molecular cloning, characterization, and inhibition studies of a β-carbonic anhydrase from Malassezia globosa, a potential antidandruff target. | Journal of medicinal chemistry 20120412 |
Pyrazolo[4,3-c][1,2]benzothiazines 5,5-dioxide: a promising new class of Staphylococcus aureus NorA efflux pump inhibitors. | Journal of medicinal chemistry 20120412 |
Cytoprotective effect of nonsteroidal antiinflammatory drugs in rat brain slices subjected to reoxygenation after oxygen-glucose deprivation. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120411 |
Inclusion of celecoxib into fibrous ordered mesoporous carbon for enhanced oral bioavailability and reduced gastric irritancy. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20120411 |
A practical model of osteomyelitis-induced bone pain by intra-tibial injection of Staphylococcus aureus in rats. | Neuroscience letters 20120404 |
Enhancement of amorphous celecoxib stability by mixing it with octaacetylmaltose: the molecular dynamics study. | Molecular pharmaceutics 20120402 |
Effects of non-steroidal anti-inflammatory drug treatments on cognitive decline vary by phase of pre-clinical Alzheimer disease: findings from the randomized controlled Alzheimer's Disease Anti-inflammatory Prevention Trial. | International journal of geriatric psychiatry 20120401 |
Effect of nonselective and selective COX-2 inhibitors on memory dysfunction, glutathione system, and tumor necrosis factor alpha level against cerebral ischemia reperfusion injury. | Drug and chemical toxicology 20120401 |
Randomized phase III clinical trial of a combined treatment with carnitine + celecoxib ± megestrol acetate for patients with cancer-related anorexia/cachexia syndrome. | Clinical nutrition (Edinburgh, Scotland) 20120401 |
Small bowel injury induced by selective cyclooxygenase-2 inhibitors: a prospective, double-blind, randomized clinical trial comparing celecoxib and meloxicam. | Journal of gastroenterology 20120401 |
Concordance with guideline recommendations: previous and more recent nonsteroidal anti-inflammatory drug prescriptions in Quebec, Canada. | Pharmacoepidemiology and drug safety 20120401 |
Melatonin sensitizes human hepatoma cells to endoplasmic reticulum stress-induced apoptosis. | Journal of pineal research 20120401 |
Nonsteroidal anti-inflammatory drugs in schizophrenia: ready for practice or a good start? A meta-analysis. | The Journal of clinical psychiatry 20120401 |
Up-regulation of 12(S)-lipoxygenase induces a migratory phenotype in colorectal cancer cells. | Experimental cell research 20120401 |
Glycosylation of human cyclooxygenase-2 (COX-2) decreases the efficacy of certain COX-2 inhibitors. | Pharmacological research 20120401 |
Effects of celecoxib on prostanoid biosynthesis and circulating angiogenesis proteins in familial adenomatous polyposis. | The Journal of pharmacology and experimental therapeutics 20120401 |
Effect of non-steroidal anti-inflammatory drugs and new fenamate analogues on TRPC4 and TRPC5 channels. | Biochemical pharmacology 20120401 |
Celecoxib pathways: pharmacokinetics and pharmacodynamics. | Pharmacogenetics and genomics 20120401 |
Inflammation-induced decrease in voluntary wheel running in mice: a nonreflexive test for evaluating inflammatory pain and analgesia. | Pain 20120401 |
Mutation of active site residues Asn67 to Ile, Gln92 to Val and Leu204 to Ser in human carbonic anhydrase II: influences on the catalytic activity and affinity for inhibitors. | Bioorganic & medicinal chemistry 20120401 |
Synthesis and evaluation of fluorobenzoylated di- and tripeptides as inhibitors of cyclooxygenase-2 (COX-2). | Bioorganic & medicinal chemistry 20120401 |
Re: Preventive but not curative efficacy of celecoxib on bladder carcinogenesis in a rat model. | The Journal of urology 20120401 |
CYFRA 21-1 as a prognostic and predictive marker in advanced non-small-cell lung cancer in a prospective trial: CALGB 150304. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20120401 |
Probable celecoxib-induced hepatorenal syndrome. | The Annals of pharmacotherapy 20120401 |
Automatic filtering and substantiation of drug safety signals. | PLoS computational biology 20120401 |
Phase ii trial of a metronomic schedule of docetaxel and capecitabine with concurrent celecoxib in patients with prior anthracycline exposure for metastatic breast cancer. | Current oncology (Toronto, Ont.) 20120401 |
Role of enhanced visibility in evaluating polyposis syndromes using a newly developed contrast image capsule endoscope. | Gut and liver 20120401 |
Seeing it through: translational validation of new medical imaging modalities. | Biomedical optics express 20120401 |
Role of basic science in the development of new medicines: examples from the eicosanoid field. | The Journal of biological chemistry 20120323 |
Curcumin as anti-endometriotic agent: implication of MMP-3 and intrinsic apoptotic pathway. | Biochemical pharmacology 20120315 |
Novel 5-substituted 1H-tetrazoles as cyclooxygenase-2 (COX-2) inhibitors. | Bioorganic & medicinal chemistry letters 20120315 |
N-1 and C-3 substituted indole Schiff bases as selective COX-2 inhibitors: synthesis and biological evaluation. | Bioorganic & medicinal chemistry letters 20120315 |
Cyclooxygenase-1-selective inhibitors based on the (E)-2'-des-methyl-sulindac sulfide scaffold. | Journal of medicinal chemistry 20120308 |
Effect of celecoxib on proliferation, collagen expression, ERK1/2 and SMAD2/3 phosphorylation in NIH/3T3 fibroblasts. | European journal of pharmacology 20120305 |
Hydrophilic prodrug approach for reduced pigment binding and enhanced transscleral retinal delivery of celecoxib. | Molecular pharmaceutics 20120305 |
Non-steroidal anti-inflammatory drugs and cognitive function: are prostaglandins at the heart of cognitive impairment in dementia and delirium? | Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology 20120301 |
Spectrofluorimetric determination of aliskiren in tablets and spiked human plasma through derivatization with dansyl chloride. | Journal of fluorescence 20120301 |
In vitro characterization of chitosan gels for buccal delivery of celecoxib: influence of a penetration enhancer. | AAPS PharmSciTech 20120301 |
A randomized phase III clinical trial of a combined treatment for cachexia in patients with gynecological cancers: evaluating the impact on metabolic and inflammatory profiles and quality of life. | Gynecologic oncology 20120301 |
Celecoxib suppresses fibroblast proliferation and collagen expression by inhibiting ERK1/2 and SMAD2/3 phosphorylation. | Molecular medicine reports 20120301 |
Low-dose celecoxib improves coronary function after acute myocardial ischaemia in rabbits. | Clinical and experimental pharmacology & physiology 20120301 |
Synthesis of novel 2-mercapto benzothiazole and 1,2,3-triazole based bis-heterocycles: their anti-inflammatory and anti-nociceptive activities. | European journal of medicinal chemistry 20120301 |
The APC and PreSAP trials: a post hoc noninferiority analysis using a comprehensive new measure for gastrointestinal tract injury in 2 randomized, double-blind studies comparing celecoxib and placebo. | Clinical therapeutics 20120301 |
Role of Sulindac and Celecoxib in chemoprevention of colorectal cancer via intrinsic pathway of apoptosis: exploring NHE-1, intracellular calcium homeostasis and Calpain 9. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20120301 |
Celecoxib and Bcl-2: emerging possibilities for anticancer drug design. | Future medicinal chemistry 20120301 |
Preemptive analgesic effect of low doses of celecoxib is superior to low doses of traditional nonsteroidal anti-inflammatory drugs. | The Journal of craniofacial surgery 20120301 |
Targeted therapy for hepatocellular carcinoma: novel agents on the horizon. | Oncotarget 20120301 |
Total knee arthroplasty in rheumatoid arthritis. | Knee surgery & related research 20120301 |
Rational approaches to improving selectivity in drug design. | Journal of medicinal chemistry 20120223 |
Oxidative stress-dependent cyclooxygenase-2-derived prostaglandin f(2α) impairs endothelial function in renovascular hypertensive rats. | Antioxidants & redox signaling 20120215 |
Cloning, characterization and sulfonamide inhibition studies of an α-carbonic anhydrase from the living fossil sponge Astrosclera willeyana. | Bioorganic & medicinal chemistry 20120215 |
Aspirin, steroidal and non-steroidal anti-inflammatory drugs for the treatment of Alzheimer's disease. | The Cochrane database of systematic reviews 20120215 |
Celecoxib reduces fluidity and decreases metastatic potential of colon cancer cell lines irrespective of COX-2 expression. | Bioscience reports 20120201 |
Synthesis and biological evaluation of some novel sulfamoylphenyl-pyridazinone as anti-inflammatory agents (Part-II * ). | Journal of enzyme inhibition and medicinal chemistry 20120201 |
TERC polymorphisms are associated both with susceptibility to colorectal cancer and with longer telomeres. | Gut 20120201 |
Drug-induced hypersensitivity syndrome followed by persistent arthritis. | The Journal of dermatology 20120201 |
Polymeric nanoparticles for increased oral bioavailability and rapid absorption using celecoxib as a model of a low-solubility, high-permeability drug. | Pharmaceutical research 20120201 |
Pharmacological modulation of peritoneal injury induced by dialysis fluids: is it an option? | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20120201 |
Dimethylcelecoxib induces an inhibitory complex consisting of HDAC1/NF-κB(p65)RelA leading to transcriptional downregulation of mPGES-1 and EGR1. | Cellular signalling 20120201 |
Berberine-induced AMPK activation inhibits the metastatic potential of melanoma cells via reduction of ERK activity and COX-2 protein expression. | Biochemical pharmacology 20120201 |
Low-dosage metronomic chemotherapy and angiogenesis: topoisomerase inhibitors irinotecan and mitoxantrone stimulate VEGF-A-mediated angiogenesis. | APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20120201 |
Fixed drug eruption caused by etoricoxib with tolerance to celecoxib and parecoxib. | Contact dermatitis 20120201 |
Efficacy and safety of additional 200-mg dose of celecoxib in adult patients with postoperative pain following extraction of impacted third mandibular molar: a multicenter, randomized, double-blind, placebo-controlled, phase II study in Japan. | Clinical therapeutics 20120201 |
Early recovery after fast-track Oxford unicompartmental knee arthroplasty. 35 patients with minimal invasive surgery. | Acta orthopaedica 20120201 |
(E)-3,5-Dimethyl-1-p-tolyl-4-(p-tolyl-diazen-yl)-1H-pyrazole. | Acta crystallographica. Section E, Structure reports online 20120201 |
Ethyl 2-[(2,4-difluoro-phen-yl)hydrazinyl-idene]-3-oxobutano-ate. | Acta crystallographica. Section E, Structure reports online 20120201 |
A continuous infusion fascia iliaca compartment block in hip fracture patients: a pilot study. | Journal of clinical medicine research 20120201 |
Novel marine phenazines as potential cancer chemopreventive and anti-inflammatory agents. | Marine drugs 20120201 |
[Clinical efficacy of bushen huoxue qubi decoction on treatment of knee-osteoarthritis and its effect on hemarheology, anti-inflammation and antioxidation]. | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20120201 |
[Chemoprevention of oral cancer--clinical and experimental studies]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20120201 |
Enzymatic transformation of caffeic acid with enhanced cyclooxygenase-2 inhibitory activity. | Bioorganic & medicinal chemistry letters 20120115 |
Restoration of tumor suppressor p53 by differentially regulating pro- and anti-p53 networks in HPV-18-infected cervical cancer cells. | Oncogene 20120112 |
Diagnosis and treatment of acute ankle injuries: development of an evidence-based algorithm. | Orthopedic reviews 20120102 |
An experimental study of low-level laser therapy in rat Achilles tendon injury. | Lasers in medical science 20120101 |
Metabolism of tocotrienols in animals and synergistic inhibitory actions of tocotrienols with atorvastatin in cancer cells. | Genes & nutrition 20120101 |
Cooperative enhancement of radiosensitivity after combined treatment of 17-(allylamino)-17-demethoxygeldanamycin and celecoxib in human lung and colon cancer cell lines. | DNA and cell biology 20120101 |
The COX-2 inhibitor Celecoxib enhances the sensitivity of KB/VCR oral cancer cell lines to Vincristine by down-regulating P-glycoprotein expression and function. | Prostaglandins & other lipid mediators 20120101 |
The nonsteroidal anti-inflammatory drug celecoxib suppresses the growth and induces apoptosis of human glioblastoma cells via the NF-κB pathway. | Journal of neuro-oncology 20120101 |
Quality by design approach for developing chitosan-Ca-alginate microspheres for colon delivery of celecoxib-hydroxypropyl-β-cyclodextrin-PVP complex. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20120101 |
Nitric oxide synthase inhibition abrogates hydrogen sulfide-induced cardioprotection in mice. | Molecular and cellular biochemistry 20120101 |
Lack of a chondroprotective effect of cyclooxygenase 2 inhibition in a surgically induced model of osteoarthritis in mice. | Arthritis and rheumatism 20120101 |
Changing the outcome of osteoarthritis: still a challenge for cyclooxygenase 2 inhibitors. | Arthritis and rheumatism 20120101 |
Barrier coated drug layered particles for enhanced performance of amorphous solid dispersion dosage form. | Journal of pharmaceutical sciences 20120101 |
Utility of vascular endothelial growth factor inhibitors in the treatment of ovarian cancer: from concept to application. | Journal of oncology 20120101 |
Kv7 potassium channels in airway smooth muscle cells: signal transduction intermediates and pharmacological targets for bronchodilator therapy. | American journal of physiology. Lung cellular and molecular physiology 20120101 |
Tumor angiogenesis as a target for dietary cancer prevention. | Journal of oncology 20120101 |
Molecular pathogenesis of cholangiocarcinoma. | International journal of hepatology 20120101 |
Novel selective COX-1 inhibitors suppress neuroinflammatory mediators in LPS-stimulated N13 microglial cells. | Pharmacological research 20120101 |
Loss of the preconditioning effect of rosuvastatin during sustained therapy: a human in vivo study. | American journal of physiology. Heart and circulatory physiology 20120101 |
Lack of efficacy of combined antiangiogenic therapies in xenografted human melanoma. | Journal of oncology 20120101 |
Lipoprotein lipase as a candidate target for cancer prevention/therapy. | Biochemistry research international 20120101 |
The influence of UGT1A6 variants and aspirin use in a randomized trial of celecoxib for prevention of colorectal adenoma. | Cancer prevention research (Philadelphia, Pa.) 20120101 |
Effects of cyclooxygenase inhibition on cardiovascular function in a hypercholesterolemic swine model of chronic ischemia. | American journal of physiology. Heart and circulatory physiology 20120101 |
The in vivo expression of radiation-induced chromosomal instability has an inflammatory mechanism. | Radiation research 20120101 |
An update on the pathology and clinical management of gouty arthritis. | Clinical rheumatology 20120101 |
Prostaglandin E(2) potentiates methylmalonate-induced seizures. | Epilepsia 20120101 |
Constitutive overexpression of the oncogene Rac1 in the airway of recurrent respiratory papillomatosis patients is a targetable host-susceptibility factor. | Molecular medicine (Cambridge, Mass.) 20120101 |
Peripheral chondrosarcoma progression is associated with increased type X collagen and vascularisation. | Virchows Archiv : an international journal of pathology 20120101 |
Structure based drug design, synthesis and evaluation of 4-(benzyloxy)-1-phenylbut-2-yn-1-ol derivatives as 5-lipoxygenase inhibitors. | European journal of medicinal chemistry 20120101 |
Fragment-based design, docking, synthesis, biological evaluation and structure-activity relationships of 2-benzo/benzisothiazolimino-5-aryliden-4-thiazolidinones as cycloxygenase/lipoxygenase inhibitors. | European journal of medicinal chemistry 20120101 |
A high-fat diet induces bone loss in mice lacking the Alox5 gene. | Endocrinology 20120101 |
A comparison of the therapeutic efficacy of diclofenac in osteoarthritis: a systematic review of randomised controlled trials. | Current medical research and opinion 20120101 |
Adjunct treatments for schizophrenia and bipolar disorder: what to try when you are out of ideas. | Clinical schizophrenia & related psychoses 20120101 |
Effects of combination therapy with celecoxib and doxycycline on neointimal hyperplasia and inflammatory biomarkers in coronary artery disease patients treated with bare metal stents. | Yonsei medical journal 20120101 |
The role of nutraceuticals in chemoprevention and chemotherapy and their clinical outcomes. | Journal of oncology 20120101 |
Comparison of CD63 Upregulation Induced by NSAIDs on Basophils and Monocytes in Patients with NSAID Hypersensitivity. | Journal of allergy 20120101 |
Aspirin: pharmacology and clinical applications. | Thrombosis 20120101 |
Beneficial effect of ultra-low-dose aspirin in platelet activity alterations and haemorrhage observed in experimental portal hypertension. | Thrombosis 20120101 |
A systematic review and meta-analysis of efficacy, cost-effectiveness, and safety of selected complementary and alternative medicine for neck and low-back pain. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
Meloxicam-induced rhabdomyolysis in the context of an acute ross river viral infection. | Allergy, asthma & immunology research 20120101 |
Celecoxib may prevent lung cancer. | Cancer 20120101 |
Factors implicated in radiation therapy failure and radiosensitization of prostate cancer. | Prostate cancer 20120101 |
Effect of prostaglandin E2 injection on the structural properties of the rat patellar tendon. | Sports medicine, arthroscopy, rehabilitation, therapy & technology : SMARTT 20120101 |
Systemic arthritis in children: a review of clinical presentation and treatment. | International journal of inflammation 20120101 |
Interactions between prostaglandins, leukotrienes and HIV-1: possible implications for the central nervous system. | Retrovirology 20120101 |
A novel radioresistant mechanism of galectin-1 mediated by H-Ras-dependent pathways in cervical cancer cells. | Cell death & disease 20120101 |
A 4-trifluoromethyl analogue of celecoxib inhibits arthritis by suppressing innate immune cell activation. | Arthritis research & therapy 20120101 |
[Immunomodulation and antiangiogenesis in cancer therapy. From basic to clinical research]. | Medicina 20120101 |
Enhancement of Antinociception by Co-administrations of Nefopam, Morphine, and Nimesulide in a Rat Model of Neuropathic Pain. | The Korean journal of pain 20120101 |
The cost-effectiveness of celecoxib vs diclofenac in the treatment of osteoarthritis in the UK; an update to the NICE model using data from the CONDOR trial. | Journal of medical economics 20120101 |
Resveratrol engages AMPK to attenuate ERK and mTOR signaling in sensory neurons and inhibits incision-induced acute and chronic pain. | Molecular pain 20120101 |
Do nonsteroidal anti-inflammatory drugs affect bone healing? A critical analysis. | TheScientificWorldJournal 20120101 |
Recent advances in morphological cell image analysis. | Computational and mathematical methods in medicine 20120101 |
Expression of COX2 and p53 in Rat Esophageal Cancer Induced by Reflux of Duodenal Contents. | ISRN gastroenterology 20120101 |
Polymeric micelles based on poly(ethylene glycol) block poly(racemic amino acids) hybrid polypeptides: conformation-facilitated drug-loading behavior and potential application as effective anticancer drug carriers. | International journal of nanomedicine 20120101 |
Autocrine prostaglandin E2 signaling promotes tumor cell survival and proliferation in childhood neuroblastoma. | PloS one 20120101 |
Hepatitis C virus to hepatocellular carcinoma. | Infectious agents and cancer 20120101 |
Challenging medical ghostwriting in US courts. | PLoS medicine 20120101 |
Exhaled Eicosanoids following Bronchial Aspirin Challenge in Asthma Patients with and without Aspirin Hypersensitivity: The Pilot Study. | Journal of allergy 20120101 |
Trends in qualifying biomarkers in drug safety. Consensus of the 2011 meeting of the spanish society of clinical pharmacology. | Frontiers in pharmacology 20120101 |
Increased serum sTRAIL levels were correlated with survival in bevacizumab-treated metastatic colon cancer. | BMC cancer 20120101 |
Influence of morphine on pericyte-endothelial interaction: implications for antiangiogenic therapy. | Journal of oncology 20120101 |
Metronomic chemotherapy in advanced oral cancers. | Journal of cancer research and therapeutics 20120101 |
Modulation of CXCR3 ligand secretion by prostaglandin E2 and cyclooxygenase inhibitors in human breast cancer. | Breast cancer research : BCR 20120101 |
[A case of favorable response after combination treatment with interferon-α and cyclooxygenase-2 inhibitor against metastatic renal cell carcinoma]. | Hinyokika kiyo. Acta urologica Japonica 20120101 |
Shortening of 3'UTRs correlates with poor prognosis in breast and lung cancer. | PloS one 20120101 |
Regulation of cyclooxygenase-2 expression by heat: a novel aspect of heat shock factor 1 function in human cells. | PloS one 20120101 |
Minocycline and aspirin in the treatment of bipolar depression: a protocol for a proof-of-concept, randomised, double-blind, placebo-controlled, 2x2 clinical trial. | BMJ open 20120101 |
Hemagglutinin from the H5N1 virus activates Janus kinase 3 to dysregulate innate immunity. | PloS one 20120101 |
Arsenic trioxide enhances the radiation sensitivity of androgen-dependent and -independent human prostate cancer cells. | PloS one 20120101 |
The antinociceptive effect of electroacupuncture at different depths of acupoints and under the needling surface. | Chinese medicine 20120101 |
Who fans the flames of Alzheimer's disease brains? Misfolded tau on the crossroad of neurodegenerative and inflammatory pathways. | Journal of neuroinflammation 20120101 |
Murine models of B-cell lymphomas: promising tools for designing cancer therapies. | Advances in hematology 20120101 |
A novel LMP1 antibody synergizes with mitomycin C to inhibit nasopharyngeal carcinoma growth in vivo through inducing apoptosis and downregulating vascular endothelial growth factor. | International journal of molecular sciences 20120101 |
Endogenous opioid and cannabinoid mechanisms are involved in the analgesic effects of celecoxib in the central nervous system. | Pharmacology 20120101 |
Single dose oral celecoxib for acute postoperative pain in adults. | The Cochrane database of systematic reviews 20120101 |
Low levels of Human Cytomegalovirus Infection in Glioblastoma multiforme associates with patient survival; -a case-control study. | Herpesviridae 20120101 |
Celecoxib radiosensitizes the human cervical cancer HeLa cell line via a mechanism dependent on reduced cyclo-oxygenase-2 and vascular endothelial growth factor C expression. | The Journal of international medical research 20120101 |
Non-steroidal anti-inflammatory drugs for the treatment of pain and immobility-associated osteoarthritis: consensus guidance for primary care. | BMC family practice 20120101 |
The efficacy and safety of febuxostat for urate lowering in gout patients ≥65 years of age. | BMC geriatrics 20120101 |
Down-regulation of glucose-regulated protein (GRP) 78 potentiates cytotoxic effect of celecoxib in human urothelial carcinoma cells. | PloS one 20120101 |
Nimesulide inhibited the growth of hypopharyngeal carcinoma cells via suppressing Survivin expression. | Head & neck oncology 20120101 |
Minocycline corrects early, pre-plaque neuroinflammation and inhibits BACE-1 in a transgenic model of Alzheimer's disease-like amyloid pathology. | Journal of neuroinflammation 20120101 |
Emerging pharmacotherapies for diabetic macular edema. | Experimental diabetes research 20120101 |
Cellular-based immunotherapies for patients with glioblastoma multiforme. | Clinical & developmental immunology 20120101 |
Effect of GCSB-5, a Herbal Formulation, on Monosodium Iodoacetate-Induced Osteoarthritis in Rats. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
A randomized, double blind, placebo and active comparator controlled pilot study of UP446, a novel dual pathway inhibitor anti-inflammatory agent of botanical origin. | Nutrition journal 20120101 |
Gastrointestinal-sparing effects of novel NSAIDs in rats with compromised mucosal defence. | PloS one 20120101 |
Prostaglandins in cancer cell adhesion, migration, and invasion. | International journal of cell biology 20120101 |
Leptin in anorexia and cachexia syndrome. | International journal of peptides 20120101 |
The role of MAPK in drug-induced kidney injury. | Journal of signal transduction 20120101 |
Fraud in anaesthetic research and publication. | Indian journal of anaesthesia 20120101 |
Pathogenesis of abdominal aortic aneurysms: role of nicotine and nicotinic acetylcholine receptors. | Mediators of inflammation 20120101 |
Current trends in targeted therapies for glioblastoma multiforme. | Neurology research international 20120101 |
Tolfenamic acid induces apoptosis and growth inhibition in head and neck cancer: involvement of NAG-1 expression. | PloS one 20120101 |
Glenohumeral joint preservation: a review of management options for young, active patients with osteoarthritis. | Advances in orthopedics 20120101 |
Neuroprotective effects of meloxicam and selegiline in scopolamine-induced cognitive impairment and oxidative stress. | International journal of Alzheimer's disease 20120101 |
A further piece of the puzzle: positive FOBT, colonoscopy, aspirin and the prevention of colorectal cancer. | Digestion 20120101 |
Metronomic chemotherapy with the COMBAT regimen in advanced pediatric malignancies: a multicenter experience. | Oncology 20120101 |
Oxidative stress and microglial cells in Parkinson's disease. | Mediators of inflammation 20120101 |
Cell cycle inhibition without disruption of neurogenesis is a strategy for treatment of aberrant cell cycle diseases: an update. | TheScientificWorldJournal 20120101 |
Efficacy and Safety of Duloxetine in Patients with Chronic Low Back Pain Who Used versus Did Not Use Concomitant Nonsteroidal Anti-Inflammatory Drugs or Acetaminophen: A Post Hoc Pooled Analysis of 2 Randomized, Placebo-Controlled Trials. | Pain research and treatment 20120101 |
Health and cellular impacts of air pollutants: from cytoprotection to cytotoxicity. | Biochemistry research international 20120101 |
A chemocentric approach to the identification of cancer targets. | PloS one 20120101 |
A review: inflammatory process in Alzheimer's disease, role of cytokines. | TheScientificWorldJournal 20120101 |
Influence of Tumor Location on the Composition of Immune Infiltrate and Its Impact on Patient Survival. Lessons from DCBCL and Animal Models. | Frontiers in immunology 20120101 |
Targeting multiple-myeloma-induced immune dysfunction to improve immunotherapy outcomes. | Clinical & developmental immunology 20120101 |
Altered composition of liver proteasome assemblies contributes to enhanced proteasome activity in the exceptionally long-lived naked mole-rat. | PloS one 20120101 |
Selection of metastatic breast cancer cells based on adaptability of their metabolic state. | PloS one 20120101 |
Inhibition of EP4 signaling attenuates aortic aneurysm formation. | PloS one 20120101 |
COX-2 expression and tumor angiogenesis in thyroid carcinoma patients among northeast Chinese population-result of a single-center study. | International journal of medical sciences 20120101 |
Efficacy of etoricoxib, celecoxib, lumiracoxib, non-selective NSAIDs, and acetaminophen in osteoarthritis: a mixed treatment comparison. | The open rheumatology journal 20120101 |
Synthesis and anti-inflammatory evaluation of new substituted 1-(3-chlorophenyl)-3-(4-methoxyphenyl)-1H-pyrazole derivatives. | Acta poloniae pharmaceutica 20120101 |
Scientific evidence and rationale for the development of curcumin and resveratrol as nutraceutricals for joint health. | International journal of molecular sciences 20120101 |
Chitosan-hyaluronate hybrid gel intraarticular injection delays osteoarthritis progression and reduces pain in a rat meniscectomy model as compared to saline and hyaluronate treatment. | Advances in orthopedics 20120101 |
Antineuropathic and antinociceptive drugs combination in patients with chronic low back pain: a systematic review. | Pain research and treatment 20120101 |
Drug management of visceral pain: concepts from basic research. | Pain research and treatment 20120101 |
Adverse events in patients with blood loss: a pooled analysis of 51 clinical studies from the celecoxib clinical trial database. | The open rheumatology journal 20120101 |
Induction of selective blood-tumor barrier permeability and macromolecular transport by a biostable kinin B1 receptor agonist in a glioma rat model. | PloS one 20120101 |
Expressions of MMPs and TIMP-1 in gastric ulcers may differentiate H. pylori-infected from NSAID-related ulcers. | TheScientificWorldJournal 20120101 |
Selective COX-2 inhibitor ameliorates osteoarthritis by repressing apoptosis of chondrocyte. | Medical science monitor : international medical journal of experimental and clinical research 20120101 |
Colorectal cancer chemoprevention: is this the future of colorectal cancer prevention? | TheScientificWorldJournal 20120101 |
Low-dose chemotherapy with insulin (insulin potentiation therapy) in combination with hormone therapy for treatment of castration-resistant prostate cancer. | ISRN urology 20120101 |
Treatment-resistant Schizophrenia: Evidence-based Strategies. | Mens sana monographs 20120101 |
Effect of aspirin on cell growth of human MG-63 osteosarcoma line. | TheScientificWorldJournal 20120101 |
The yin and yang of nrf2-regulated selenoproteins in carcinogenesis. | International journal of cell biology 20120101 |
Current knowledge on pancreatic cancer. | Frontiers in oncology 20120101 |
Indomethacin reduces glomerular and tubular damage markers but not renal inflammation in chronic kidney disease patients: a post-hoc analysis. | PloS one 20120101 |
Eicosanoids and respiratory viral infection: coordinators of inflammation and potential therapeutic targets. | Mediators of inflammation 20120101 |
Therapeutic strategies based on polymeric microparticles. | Journal of biomedicine & biotechnology 20120101 |
The molecular biology of soft-tissue sarcomas and current trends in therapy. | Sarcoma 20120101 |
Impact of a preemptive multimodal analgesia plus femoral nerve blockade protocol on rehabilitation, hospital length of stay, and postoperative analgesia after primary total knee arthroplasty: a controlled clinical pilot study. | TheScientificWorldJournal 20120101 |
Modelling the effects of ageing time of starch on the enzymatic activity of three amylolytic enzymes. | TheScientificWorldJournal 20120101 |
Solitary fibrous tumor in the round ligament of the liver: a fortunate intraoperative discovery. | Case reports in oncology 20120101 |
Coauthorship and institutional collaborations on cost-effectiveness analyses: a systematic network analysis. | PloS one 20120101 |
GSK-3β: A Bifunctional Role in Cell Death Pathways. | International journal of cell biology 20120101 |
Transactivation of EGFR by LPS induces COX-2 expression in enterocytes. | PloS one 20120101 |
Topical polyethylene glycol as a novel chemopreventive agent for oral cancer via targeting of epidermal growth factor response. | PloS one 20120101 |
A review of fetal scarless healing. | ISRN dermatology 20120101 |
Microglial KCa3.1 Channels as a Potential Therapeutic Target for Alzheimer's Disease. | International journal of Alzheimer's disease 20120101 |
Radiation, inflammation, and immune responses in cancer. | Frontiers in oncology 20120101 |
Pain from a Bullet Lingers on: An Uncommon Case of Lead Toxicity. | Case reports in gastroenterology 20120101 |
Comment on 'Accentuation of Tumor Growth Secondary to Morphine Administration: The Proneoplastic Role of Morphine besides Its Role in Pain Management'. | Journal of oncology 20120101 |
Cucurbitacin L 2-O-β-Glucoside Demonstrates Apoptogenesis in Colon Adenocarcinoma Cells (HT-29): Involvement of Reactive Oxygen and Nitrogen Species Regulation. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
Celecoxib synergizes human pancreatic ductal adenocarcinoma cells to sorafenib-induced growth inhibition. | Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20120101 |
Anxiolytic-like effects of compound zhi zhu xiang in rats. | Evidence-based complementary and alternative medicine : eCAM 20120101 |
Extra-abdominal desmoid tumors associated with familial adenomatous polyposis. | Sarcoma 20120101 |
Inhibition of ion channels and heart beat in Drosophila by selective COX-2 inhibitor SC-791. | PloS one 20120101 |
Expression of specificity protein transcription factors in pancreatic cancer and their association in prognosis and therapy. | Current medicinal chemistry 20120101 |
Selective cyclooxygenase-2 inhibitor prevents cisplatin-induced tumorigenesis in A/J mice. | Acta medica Okayama 20120101 |
Inflammation modulates expression of laminin in the central nervous system following ischemic injury. | Journal of neuroinflammation 20120101 |
Long-term disease stabilization in a patient with castration-resistant metastatic prostate cancer by the addition of lenalidomide to low-dose dexamethasone and celecoxib. | Onkologie 20120101 |
In vitro effects of VA441, a new selective cyclooxygenase-2 inhibitor, on human osteoarthritic chondrocytes exposed to IL-1β. | Journal of pharmacological sciences 20120101 |
Activation of diverse eicosanoid pathways in osteoarthritic cartilage: a lipidomic and genomic analysis. | Bulletin of the NYU hospital for joint diseases 20120101 |
Celecoxib and GABA cooperatively prevent the progression of pancreatic cancer in vitro and in xenograft models of stress-free and stress-exposed mice. | PloS one 20120101 |
Molecular mechanism of the inhibition effect of Celecoxib on corneal collagen degradation in three dimensions. | International journal of ophthalmology 20120101 |
Effects of cyclooxygenase inhibitors in combination with taxol on expression of cyclin D1 and Ki-67 in a xenograft model of ovarian carcinoma. | International journal of molecular sciences 20120101 |
In vivo optical molecular imaging of matrix metalloproteinase activity following celecoxib therapy for colorectal cancer. | Molecular imaging 20120101 |
Role of APOE and Age at Enrollment in the Alzheimer's Disease Anti-Inflammatory Prevention Trial (ADAPT). | Dementia and geriatric cognitive disorders extra 20120101 |
Efficacy and tolerability of celecoxib versus naproxen in patients with osteoarthritis of the knee: a randomized, double-blind, double-dummy trial. | The Journal of international medical research 20120101 |
Simultaneous Determination of Celecoxib, Erlotinib, and its Metabolite Desmethyl-Erlotinib (OSI-420) in Rat Plasma by Liquid chromatography/Tandem Mass Spectrometry with Positive/Negative Ion-Switching Electrospray Ionisation. | Scientia pharmaceutica 20120101 |
Comparative study of liposomes, transfersomes and ethosomes as carriers for improving topical delivery of celecoxib. | Drug delivery 20120101 |
[Chronic infection urethroprostatit: a new look at old problem]. | Urologiia (Moscow, Russia : 1999) 20120101 |
Celecoxib: a review of its use for symptomatic relief in the treatment of osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. | Drugs 20111224 |
Inhibition of cyclooxygenase-2 impacts chondrocyte hypertrophic differentiation during endochondral ossification. | European cells & materials 20111219 |
Protection against titanium particle-induced osteoclastogenesis by cyclooxygenase-2 selective inhibitor. | Journal of biomedical materials research. Part A 20111215 |
PGE(2)-induced CXCL12 production and CXCR4 expression controls the accumulation of human MDSCs in ovarian cancer environment. | Cancer research 20111215 |
COX-2 inhibition does not reverse the increased sympathetic modulation in MSG obese rats. | Autonomic neuroscience : basic & clinical 20111207 |
Chemopreventive effects of non-steroidal anti-inflammatory drugs in early neoplasm of experimental colorectal cancer: an apoptosome study. | Journal of gastrointestinal cancer 20111201 |
Cancer chemoprevention by targeting the epigenome. | Current drug targets 20111201 |
Cyclooxygenase as a target for colorectal cancer chemoprevention. | Current drug targets 20111201 |
Dual blockade of the EGFR and COX-2 pathways: a phase II trial of cetuximab and celecoxib in patients with chemotherapy refractory metastatic colorectal cancer. | American journal of clinical oncology 20111201 |
Drug-induced Sweet's syndrome by aceclofenac. | Cutaneous and ocular toxicology 20111201 |
Sweet's syndrome associated with the intake of a selective cyclooxygenase-2 (COX-2) inhibitor. | Cutaneous and ocular toxicology 20111201 |
The use of spray-drying to enhance celecoxib solubility. | Drug development and industrial pharmacy 20111201 |
Role of COX-2 in the bioactivation of methylenedianiline and in its proliferative effects in vascular smooth muscle cells. | Cardiovascular toxicology 20111201 |
Non steroidal anti-inflammatory drugs modulate the physicochemical properties of plasma membrane in experimental colorectal cancer: a fluorescence spectroscopic study. | Molecular and cellular biochemistry 20111201 |
Antiangiogenic treatment as a pre-operative management of alveolar soft-part sarcoma. | Pediatric blood & cancer 20111201 |
Celecoxib for recurrent sclerouveitis after syphilitic panuveitis. A case report. | Journal of ophthalmic inflammation and infection 20111201 |
Stroke risk and NSAIDs: a systematic review of observational studies. | Pharmacoepidemiology and drug safety 20111201 |
The role of the EP receptors for prostaglandin E2 in skin and skin cancer. | Cancer metastasis reviews 20111201 |
A fixed-dose combination of naproxen and esomeprazole magnesium has comparable upper gastrointestinal tolerability to celecoxib in patients with osteoarthritis of the knee: results from two randomized, parallel-group, placebo-controlled trials. | Annals of medicine 20111201 |
Synthesis and biological evaluation of some new 2-pyrazolines bearing benzene sulfonamide moiety as potential anti-inflammatory and anti-cancer agents. | European journal of medicinal chemistry 20111201 |
Case scenario: opioid association with serotonin syndrome: implications to the practitioners. | Anesthesiology 20111201 |
Treatment of osteoarthritis with continuous versus intermittent celecoxib. | The Journal of rheumatology 20111201 |
Analysing the role of COX-2 in acute oesophagitis and in melatonin-exerted protection against experimental reflux oesophagitis in rats. | The Journal of pharmacy and pharmacology 20111201 |
Survival and prognostic factors in chondrosarcoma: results in 115 patients with long-term follow-up. | Acta orthopaedica 20111201 |
Why still in hospital after fast-track hip and knee arthroplasty? | Acta orthopaedica 20111201 |
Single-level anterior cervical discectomy and interbody fusion using PEEK anatomical cervical cage and allograft bone. | Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology 20111201 |
Celecoxib-induced erythema multiforme-type drug eruption with a positive patch test. | The Journal of dermatology 20111201 |
Comparison and validation of data-mining indices for signal detection: using the Korean national health insurance claims database. | Pharmacoepidemiology and drug safety 20111201 |
Pragmatic decisions over nonsteroidal antiinflammatory drug treatment in osteoarthritis--continuous versus intermittent. | The Journal of rheumatology 20111201 |
Pilot study of a pediatric metronomic 4-drug regimen. | Oncotarget 20111201 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps). | PLoS computational biology 20111201 |
Roles of serotonergic and adrenergic receptors in the antinociception of selective cyclooxygenase-2 inhibitor in the rat spinal cord. | The Korean journal of pain 20111201 |
Is human cytomegalovirus a target in cancer therapy? | Oncotarget 20111201 |
A case of celecoxib induced acute generalized exanthematous pustulosis. | Annals of dermatology 20111201 |
Novel analgesic/anti-inflammatory agents: diarylpyrrole acetic esters endowed with nitric oxide releasing properties. | Journal of medicinal chemistry 20111124 |
Novel selective Cox-2 inhibitors induce apoptosis in Caco-2 colorectal carcinoma cell line. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20111120 |
COX-2 inhibitors block chemotherapeutic agent-induced apoptosis prior to commitment in hematopoietic cancer cells. | Biochemical pharmacology 20111115 |
A double prodrug system for colon targeting of benzenesulfonamide COX-2 inhibitors. | Bioorganic & medicinal chemistry letters 20111115 |
Design, synthesis and biological evaluation of pyridine acyl sulfonamide derivatives as novel COX-2 inhibitors. | Bioorganic & medicinal chemistry 20111115 |
Randomized, placebo-controlled phase III study of docetaxel plus carboplatin with celecoxib and cyclooxygenase-2 expression as a biomarker for patients with advanced non-small-cell lung cancer: the NVALT-4 study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20111110 |
Safety of non-steroidal anti-inflammatory drugs, including aspirin and paracetamol (acetaminophen) in people receiving methotrexate for inflammatory arthritis (rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, other spondyloarthritis). | The Cochrane database of systematic reviews 20111109 |
Clinical significance of vasculogenic mimicry in human gliomas. | Journal of neuro-oncology 20111101 |
Characteristics and molecular basis of celecoxib modulation on K(v)7 potassium channels. | British journal of pharmacology 20111101 |
A 13-week, multicenter, randomized, double-blind study of lumiracoxib in hip osteoarthritis. | Clinical rheumatology 20111101 |
Elevated macrophage migration inhibitory factor and decreased transforming growth factor-beta levels in major depression--no influence of celecoxib treatment. | Journal of affective disorders 20111101 |
Gastric juice prostaglandins and peptide growth factors as potential markers of chronic atrophic gastritis, intestinal metaplasia and gastric cancer: their potential clinical implications based on this pilot study. | Digestive diseases and sciences 20111101 |
Association of stem-like cells in gender-specific chemoprevention against intestinal neoplasia in MIN mouse. | Oncology reports 20111101 |
Coxibs and other nonsteroidal anti-inflammatory drugs in animal models of cancer chemoprevention. | Cancer prevention research (Philadelphia, Pa.) 20111101 |
The acid sphingomyelinase inhibitors block interferon-α-induced serotonin uptake via a COX-2/Akt/ERK/STAT-dependent pathway in T cells. | International immunopharmacology 20111101 |
A 78-year-old woman with an acute eosinophilic gastroenteritis. | Clinics and research in hepatology and gastroenterology 20111101 |
The structure of NS-398 bound to cyclooxygenase-2. | Journal of structural biology 20111101 |
Serum vascular endothelial growth factor and COX-2/5-LOX inhibition in advanced non-small cell lung cancer: Cancer and Leukemia Group B 150304. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20111101 |
Onsenal: marketing authorisation withdrawn in the European Union. Company failed to supply required data. | Prescrire international 20111101 |
[Survivin gene silencing inhibits the proliferation of human gastric cancer MGC-803 cells and enhances their sensitivity to celecoxib]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20111101 |
SHINBARO, a new herbal medicine with multifunctional mechanism for joint disease: first therapeutic application for the treatment of osteoarthritis. | Archives of pharmacal research 20111101 |
[Is retardation of radiologic progression of ankylosing spondylitis possible?]. | Vnitrni lekarstvi 20111101 |
Chemopreventive activity of vitamin E in breast cancer: a focus on γ- and δ-tocopherol. | Nutrients 20111101 |
A preliminary randomized double-blind clinical trial on the efficacy of celecoxib as an adjunct in the treatment of obsessive-compulsive disorder. | Psychiatry research 20111030 |
A novel inhibitor of focal adhesion signaling induces caspase-independent cell death in diffuse large B-cell lymphoma. | Blood 20111020 |
Use of nonaspirin nonsteroidal anti-inflammatory drugs during pregnancy and the risk of spontaneous abortion. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20111018 |
Isomeric acetoxy analogs of celecoxib and their evaluation as cyclooxygenase inhibitors. | Bioorganic & medicinal chemistry letters 20111015 |
Efficient synthesis of apricoxib, CS-706, a selective cyclooxygenase-2 inhibitor, and evaluation of inhibition of prostaglandin E2 production in inflammatory breast cancer cells. | Bioorganic & medicinal chemistry letters 20111015 |
Endocannabinoid oxygenation by cyclooxygenases, lipoxygenases, and cytochromes P450: cross-talk between the eicosanoid and endocannabinoid signaling pathways. | Chemical reviews 20111012 |
Detection of human cytomegalovirus in medulloblastomas reveals a potential therapeutic target. | The Journal of clinical investigation 20111003 |
Titanium, sinusitis, and the yellow nail syndrome. | Biological trace element research 20111001 |
Randomized controlled trial of the efficacy of isosorbide-SR addition to current treatment in medical expulsive therapy for ureteral calculi. | Urological research 20111001 |
The risk of coronary thrombosis with cyclo-oxygenase-2 inhibitors does not vary with polymorphisms in two regions of the cyclo-oxygenase-2 gene. | British journal of clinical pharmacology 20111001 |
Non-steroidal anti-inflammatory drugs and risk of lower gastrointestinal adverse events: a nationwide study in Taiwan. | Gut 20111001 |
Proton pump inhibitors exacerbate NSAID-induced small intestinal injury by inducing dysbiosis. | Gastroenterology 20111001 |
COX-2 regulates the proliferation of glioma stem like cells. | Neurochemistry international 20111001 |
Haemoglobin decreases in NSAID users over time: an analysis of two large outcome trials. | Alimentary pharmacology & therapeutics 20111001 |
Phenylethynylbenzenesulfonamide regioisomers strongly and selectively inhibit the transmembrane, tumor-associated carbonic anhydrase isoforms IX and XII over the cytosolic isoforms I and II. | Bioorganic & medicinal chemistry letters 20111001 |
Celecoxib promotes c-FLIP degradation through Akt-independent inhibition of GSK3. | Cancer research 20111001 |
A randomized controlled trial of celecoxib to prevent recurrence of nonmuscle-invasive bladder cancer. | Cancer prevention research (Philadelphia, Pa.) 20111001 |
Boxing bladder cancer with COX-2-specific inhibition. | Cancer prevention research (Philadelphia, Pa.) 20111001 |
Fluorinated COX-2 inhibitors as agents in PET imaging of inflammation and cancer. | Cancer prevention research (Philadelphia, Pa.) 20111001 |
Vascular mechanisms involved in angiotensin II-induced venoconstriction in hypertensive rats. | Peptides 20111001 |
Characterization of a new animal model for evaluation and treatment of back pain due to lumbar facet joint osteoarthritis. | Arthritis and rheumatism 20111001 |
Cutaneous reactions to non-steroidal anti-inflammatory drugs. | Journal of drugs in dermatology : JDD 20111001 |
Enhancing antitumor effects in pancreatic cancer cells by combined use of COX-2 and 5-LOX inhibitors. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20111001 |
Ethyl 2-[2-(2-meth-oxy-phen-yl)hydrazinyl-idene]-3-oxobutano-ate. | Acta crystallographica. Section E, Structure reports online 20111001 |
4-[2-(4-Chloro-phen-yl)hydrazinyl-idene]-3-methyl-5-oxo-4,5-dihydro-1H-pyrazole-1-carbothio-amide. | Acta crystallographica. Section E, Structure reports online 20111001 |
Ethyl 2-[2-(3-meth-oxy-phen-yl)hydrazinyl-idene]-3-oxobutano-ate. | Acta crystallographica. Section E, Structure reports online 20111001 |
Genome protective effect of metformin as revealed by reduced level of constitutive DNA damage signaling. | Aging 20111001 |
[Advances in gastrointestinal disorders associated with non-steroidal antiinflammatory agents and aspirin]. | Gastroenterologia y hepatologia 20111001 |
Nitric oxide-releasing aspirin but not conventional aspirin improves healing of experimental colitis. | World journal of gastroenterology 20110928 |
Chemical and in vitro enzymatic stability of newly synthesized celecoxib lipophilic and hydrophilic amides. | International journal of pharmaceutics 20110915 |
Interaction of celecoxib with different anti-cancer drugs is antagonistic in breast but not in other cancer cells. | Toxicology and applied pharmacology 20110915 |
Gastroprotective and safety effects of WIN-34B, a novel treatment for osteoarthritis, compared to NSAIDs. | Journal of ethnopharmacology 20110902 |
Efficacy of celecoxib, meloxicam and paracetamol in elderly Kashin-Beck disease (KBD) patients. | International orthopaedics 20110901 |
The use of etoricoxib and celecoxib for pain prevention after periodontal surgery: a double-masked, parallel-group, placebo-controlled, randomized clinical trial. | Journal of periodontology 20110901 |
Activation of vascular KCNQ (Kv7) potassium channels reverses spasmogen-induced constrictor responses in rat basilar artery. | British journal of pharmacology 20110901 |
Letter to the editor re Mani et al. | British journal of pharmacology 20110901 |
Inhibitory effect of celecoxib in lung carcinoma by regulation of cyclooxygenase-2/cytosolic phospholipase A₂ and peroxisome proliferator-activated receptor gamma. | Molecular and cellular biochemistry 20110901 |
Silica-lipid hybrid (SLH) versus non-lipid formulations for optimising the dose-dependent oral absorption of celecoxib. | Pharmaceutical research 20110901 |
Role of COX-2 in lymphangiogenesis and restoration of lymphatic flow in secondary lymphedema. | Laboratory investigation; a journal of technical methods and pathology 20110901 |
Effectiveness of the association micronized N-Palmitoylethanolamine (PEA)-transpolydatin in the treatment of chronic pelvic pain related to endometriosis after laparoscopic assessment: a pilot study. | European journal of obstetrics, gynecology, and reproductive biology 20110901 |
Synthesis and preliminary in vitro biological evaluation of new carbon-11-labeled celecoxib derivatives as candidate PET tracers for imaging of COX-2 expression in cancer. | European journal of medicinal chemistry 20110901 |
Benefits of prolonged postoperative cyclooxygenase-2 inhibitor administration on total knee arthroplasty recovery: a double-blind, placebo-controlled study. | The Journal of arthroplasty 20110901 |
COX-2 inhibition alters the phenotype of tumor-associated macrophages from M2 to M1 in ApcMin/+ mouse polyps. | Carcinogenesis 20110901 |
Established and novel NF-κB inhibitors lead to downregulation of TLR3 and the proliferation and cytokine secretion in HNSCC. | Oral oncology 20110901 |
Hypercholesterolemia and chronic ischemia alter myocardial responses to selective cyclooxygenase-2 inhibition. | The Journal of thoracic and cardiovascular surgery 20110901 |
Irish Medicines Board safety warnings: do they affect prescribing rates in primary care? | Pharmacoepidemiology and drug safety 20110901 |
The role of morphine in regulation of cancer cell growth. | Naunyn-Schmiedeberg's archives of pharmacology 20110901 |
Potential interaction of natural dietary bioactive compounds with COX-2. | Journal of molecular graphics & modelling 20110901 |
Randomized controlled trials of COX-2 inhibitors: an analysis of doses used and trends over time to investigate implications for comparative safety. | Drug safety 20110901 |
Cost-effectiveness of aspirin, celecoxib, and calcium chemoprevention for colorectal cancer. | Clinical therapeutics 20110901 |
Cox-2 inhibitors induce early c-Myc downregulation and lead to expression of differentiation markers in leukemia cells. | Cell cycle (Georgetown, Tex.) 20110901 |
Phased whole-genome genetic risk in a family quartet using a major allele reference sequence. | PLoS genetics 20110901 |
Cardiovascular risk with non-steroidal anti-inflammatory drugs: systematic review of population-based controlled observational studies. | PLoS medicine 20110901 |
Differential effects of treadmill exercise on cyclooxygenase-2 in the rat hippocampus at early and chronic stages of diabetes. | Laboratory animal research 20110901 |
Clinical significance of protein expression of cyclooxygenase-2 and somatostatin receptors in gastroenteropancreatic neuroendocrine tumors. | Cancer research and treatment : official journal of Korean Cancer Association 20110901 |
4-(5-Phenyl-3-trifluoro-meth-yl-1H-pyrazol-1--yl)benzene-sulfonamide. | Acta crystallographica. Section E, Structure reports online 20110901 |
Clinical significance of anti-mitochondrial antibodies in a patient with chronic graft-versus-host disease following hematopoietic stem cell transplantation. | The Korean journal of hematology 20110901 |
Analysis of angiogenic factors and cyclooxygenase-2 expression in cartilaginous tumors- clinical and histological correlation. | Clinics (Sao Paulo, Brazil) 20110901 |
Profound urinary protein loss and acute renal failure caused by cyclooxygenase-2 inhibitor. | The Chinese journal of physiology 20110831 |
Inhibition studies of the β-carbonic anhydrases from the bacterial pathogen Salmonella enterica serovar Typhimurium with sulfonamides and sulfamates. | Bioorganic & medicinal chemistry 20110815 |
Effects of β-glucosidase hydrolyzed products of harpagide and harpagoside on cyclooxygenase-2 (COX-2) in vitro. | Bioorganic & medicinal chemistry 20110815 |
Fragment-based drug design and drug repositioning using multiple ligand simultaneous docking (MLSD): identifying celecoxib and template compounds as novel inhibitors of signal transducer and activator of transcription 3 (STAT3). | Journal of medicinal chemistry 20110811 |
Postpartum mammary gland involution drives progression of ductal carcinoma in situ through collagen and COX-2. | Nature medicine 20110807 |
Preoperative chemoradiation for rectal cancer using capecitabine and celecoxib correlated with posttreatment assessment of thymidylate synthase and thymidine phosphorylase expression. | International journal of radiation oncology, biology, physics 20110801 |
Simvastatin improves learning and memory in control but not in olfactory bulbectomized rats. | Psychopharmacology 20110801 |
Clinical and immunomodulatory effects of celecoxib plus interferon-alpha in metastatic renal cell carcinoma patients with COX-2 tumor immunostaining. | Journal of clinical immunology 20110801 |
Celecoxib inhibits interleukin-6/interleukin-6 receptor-induced JAK2/STAT3 phosphorylation in human hepatocellular carcinoma cells. | Cancer prevention research (Philadelphia, Pa.) 20110801 |
Fast-track revision knee arthroplasty. A feasibility study. | Acta orthopaedica 20110801 |
Celecoxib induces cell apoptosis coupled with up-regulation of the expression of VEGF by a mechanism involving ER stress in human colorectal cancer cells. | Oncology reports 20110801 |
Control of experimental pulmonary tuberculosis depends more on immunostimulatory leukotrienes than on the absence of immunosuppressive prostaglandins. | Prostaglandins, leukotrienes, and essential fatty acids 20110801 |
Celecoxib does not alter cardiovascular and renal function during dietary salt loading. | Clinical and experimental pharmacology & physiology 20110801 |
Pharmacology of peripheral opioid receptors. | Current opinion in anaesthesiology 20110801 |
The inhibitory effect of celecoxib and rosiglitazone on experimental endometriosis. | Fertility and sterility 20110801 |
An investigation into the dissolution properties of celecoxib melt extrudates: understanding the role of polymer type and concentration in stabilizing supersaturated drug concentrations. | Molecular pharmaceutics 20110801 |
Plasma levels of vascular endothelial growth factor during and after radiotherapy in combination with celecoxib in patients with advanced head and neck cancer. | Oral oncology 20110801 |
Phase I clinical trial of nasopharyngeal radiotherapy and concurrent celecoxib for patients with locoregionally advanced nasopharyngeal carcinoma. | Oral oncology 20110801 |
Analogue-based design, synthesis and molecular docking analysis of 2,3-diaryl quinazolinones as non-ulcerogenic anti-inflammatory agents. | Bioorganic & medicinal chemistry 20110801 |
Phase II trial of neoadjuvant exemestane in combination with celecoxib in postmenopausal women who have breast cancer. | Clinical breast cancer 20110801 |
High-volume infiltration analgesia in bilateral hip arthroplasty. A randomized, double-blind placebo-controlled trial. | Acta orthopaedica 20110801 |
Multicentre trial in people with arthritis finds increased risk of clinically significant gastrointestinal events with diclofenac plus omeprazole compared with celecoxib. | Evidence-based medicine 20110801 |
Comparison of different loading dose of celecoxib on postoperative anti-inflammation and analgesia in patients undergoing endoscopic nasal surgery-200 mg is equivalent to 400 mg. | Pain medicine (Malden, Mass.) 20110801 |
Cardiovascular risk markers and mechanisms in targeting the COX pathway for colorectal cancer prevention. | Cancer prevention research (Philadelphia, Pa.) 20110801 |
C-reactive protein and risk of colorectal adenoma according to celecoxib treatment. | Cancer prevention research (Philadelphia, Pa.) 20110801 |
Nitric Oxide (NO) and Cyclooxygenase-2 (COX-2) Cross-Talk in Co-Cultures of Tumor Spheroids with Normal Cells. | Cancer microenvironment : official journal of the International Cancer Microenvironment Society 20110801 |
COX-2 inhibitor, celecoxib, may prevent lung cancer. | Oncology (Williston Park, N.Y.) 20110801 |
Up-regulation of cyclooxygenase-2-derived prostaglandin E(2) in colon cancer cells resistant to 5-fluorouracil. | Journal of the Korean Surgical Society 20110801 |
(Z)-Ethyl 2-cyano-2-{2-[5,6-dimethyl-4-(thio-phen-2-yl)-1H-pyrazolo-[3,4-b]pyridin-3-yl]hydrazinylidene}acetate. | Acta crystallographica. Section E, Structure reports online 20110801 |
Chemoprevention in familial adenomatous polyposis. | Best practice & research. Clinical gastroenterology 20110801 |
In vitro and in vivo inhibitory effect of three Cox-2 inhibitors and epithelial-to-mesenchymal transition in human bladder cancer cell lines. | British journal of cancer 20110726 |
The importance of cyclooxygenase 2-mediated oxidative stress in obesity-induced muscular insulin resistance in high-fat-fed rats. | Life sciences 20110718 |
Zinc deficiency activates S100A8 inflammation in the absence of COX-2 and promotes murine oral-esophageal tumor progression. | International journal of cancer 20110715 |
Phase 1 trial of concurrent erlotinib, celecoxib, and reirradiation for recurrent head and neck cancer. | Cancer 20110715 |
Synthesis of some new 1,3,5-trisubstituted pyrazolines bearing benzene sulfonamide as anticancer and anti-inflammatory agents. | Bioorganic & medicinal chemistry letters 20110715 |
Discovery and biological evaluation of a novel class of dual microsomal prostaglandin E2 synthase-1/5-lipoxygenase inhibitors based on 2-[(4,6-diphenethoxypyrimidin-2-yl)thio]hexanoic acid. | Journal of medicinal chemistry 20110714 |
Defects in mouse nephrogenesis induced by selective and non-selective cyclooxygenase-2 inhibitors. | British journal of pharmacology 20110701 |
Celecoxib and 2,5-dimethyl-celecoxib prevent cardiac remodeling inhibiting Akt-mediated signal transduction in an inherited dilated cardiomyopathy mouse model. | The Journal of pharmacology and experimental therapeutics 20110701 |
Efficacy of low-dose celecoxib in patients with acute pain. | The journal of pain : official journal of the American Pain Society 20110701 |
Combination of GSH trapping and time-dependent inhibition assays as a predictive method of drugs generating highly reactive metabolites. | Drug metabolism and disposition: the biological fate of chemicals 20110701 |
Effect of evening primrose oil and ω-3 polyunsaturated fatty acids on the cardiovascular risk of celecoxib in rats. | Journal of cardiovascular pharmacology 20110701 |
SOM230 combined with celecoxib prolongs the survival in nude mice with HepG-2 xenografts. | Cancer biology & therapy 20110701 |
Gastrointestinal tolerability of NSAIDs in elderly patients: a pooled analysis of 21 randomized clinical trials with celecoxib and nonselective NSAIDs. | Current medical research and opinion 20110701 |
Effect of celecoxib on survival in patients with advanced non-small cell lung cancer: a double blind randomised clinical phase III trial (CYCLUS study) by the Swedish Lung Cancer Study Group. | European journal of cancer (Oxford, England : 1990) 20110701 |
Harmful effects of NSAIDs among patients with hypertension and coronary artery disease. | The American journal of medicine 20110701 |
Risk of hospitalization for upper gastrointestinal adverse events associated with nonsteroidal anti-inflammatory drugs: a nationwide case-crossover study in Taiwan. | Pharmacoepidemiology and drug safety 20110701 |
A diazen-1-ium-1,2-diolated nitric oxide donor ester prodrug of 3-(4-hydroxymethylphenyl)-4-(4-methanesulfonylphenyl)-5H-furan-2-one: synthesis, biological evaluation and nitric oxide release studies. | Bioorganic & medicinal chemistry letters 20110701 |
A low carbohydrate, high protein diet slows tumor growth and prevents cancer initiation. | Cancer research 20110701 |
Is there a common upstream link for autophagic and apoptotic cell death in human high-grade gliomas? | Neuro-oncology 20110701 |
Treatment targets in intracerebral hemorrhage. | Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics 20110701 |
The dawn of a revolution in personalized lung cancer prevention. | Cancer prevention research (Philadelphia, Pa.) 20110701 |
Lung cancer chemoprevention with celecoxib in former smokers. | Cancer prevention research (Philadelphia, Pa.) 20110701 |
Extended results of the Alzheimer's disease anti-inflammatory prevention trial. | Alzheimer's & dementia : the journal of the Alzheimer's Association 20110701 |
Celecoxib and acetylbritannilactone interact synergistically to suppress breast cancer cell growth via COX-2-dependent and -independent mechanisms. | Cell death & disease 20110701 |
Features of microglia and neuroinflammation relevant to environmental exposure and neurotoxicity. | International journal of environmental research and public health 20110701 |
[Effects of celecoxib combined with radiotherapy on apoptosis of CNE-2Z cell lines]. | Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20110701 |
Preparation of microspheres containing low solubility drug compound by electrohydrodynamic spraying. | International journal of pharmaceutics 20110630 |
How a new stratified adaptive phase II design could improve targeting population. | Statistics in medicine 20110615 |
Mitragynine inhibits the COX-2 mRNA expression and prostaglandin E₂ production induced by lipopolysaccharide in RAW264.7 macrophage cells. | Journal of ethnopharmacology 20110614 |
Continuous low-dose cyclophosphamide and methotrexate combined with celecoxib for patients with advanced cancer. | British journal of cancer 20110607 |
Resveratrol in combination with other dietary polyphenols concomitantly enhances antiproliferation and UGT1A1 induction in Caco-2 cells. | Life sciences 20110606 |
Role of α-relaxation on crystallization of amorphous celecoxib above T(g) probed by dielectric spectroscopy. | Molecular pharmaceutics 20110606 |
Role of COX-2 in tumorospheres derived from a breast cancer cell line. | The Journal of surgical research 20110601 |
Optimization of cell-based assays to quantify the anti-inflammatory/allergic potential of test substances in 96-well format. | Inflammopharmacology 20110601 |
The effect of COX-2 inhibitor on capecitabine-induced hand-foot syndrome in patients with stage II/III colorectal cancer: a phase II randomized prospective study. | Journal of cancer research and clinical oncology 20110601 |
Incidence and influence on referral of primary stabbing headache in an outpatient headache clinic. | The journal of headache and pain 20110601 |
Investigation of atypical dissolution behavior of an encapsulated amorphous solid dispersion. | Journal of pharmaceutical sciences 20110601 |
The prostaglandin E2 receptor, EP2, regulates survivin expression via an EGFR/STAT3 pathway in UVB-exposed mouse skin. | Molecular carcinogenesis 20110601 |
All-cause mortality of elderly Australian veterans using COX-2 selective or non-selective NSAIDs: a longitudinal study. | British journal of clinical pharmacology 20110601 |
IL-17RA aptamer-mediated repression of IL-6 inhibits synovium inflammation in a murine model of osteoarthritis. | Osteoarthritis and cartilage 20110601 |
Celecoxib extends C. elegans lifespan via inhibition of insulin-like signaling but not cyclooxygenase-2 activity. | Aging cell 20110601 |
Clinical characteristics and outcomes in familial adenomatous polyposis patients with a long-term treatment of celecoxib: a matched cohort study. | Familial cancer 20110601 |
Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starting as early as 6 months after initiation of therapy: a randomised, double-blind, placebo-controlled pilot study using MRI. | Annals of the rheumatic diseases 20110601 |
COX-2-dependent and COX-2-independent mode of action of celecoxib in human liver cancer cells. | Omics : a journal of integrative biology 20110601 |
Biology of Cox-2: an application in cancer therapeutics. | Current drug targets 20110601 |
Regression of prostate tumors upon combination of hormone ablation therapy and celecoxib in vivo. | The Prostate 20110601 |
Of timing and surrogates: a way forward for cancer chemoprevention. | Clinical cancer research : an official journal of the American Association for Cancer Research 20110601 |
Five-year analysis of the prevention of colorectal sporadic adenomatous polyps trial. | The American journal of gastroenterology 20110601 |
Fixed-dose combination of enteric-coated naproxen and immediate-release esomeprazole has comparable efficacy to celecoxib for knee osteoarthritis: two randomized trials. | Current medical research and opinion 20110601 |
Preoperative taxane-based chemotherapy and celecoxib for carcinoma of the esophagus and gastroesophageal junction: results of a phase 2 trial. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20110601 |
2010 update of the ASAS/EULAR recommendations for the management of ankylosing spondylitis. | Annals of the rheumatic diseases 20110601 |
Synthesis and biological evaluation of loxoprofen derivatives. | Bioorganic & medicinal chemistry 20110601 |
Design, synthesis, and biological evaluation of substituted hydrazone and pyrazole derivatives as selective COX-2 inhibitors: Molecular docking study. | Bioorganic & medicinal chemistry 20110601 |
[Low-dose aspirin (LDA)/nonsteroidal anti-inflammatory drugs(NSAIDs)-induced gastrointestinal injury in Japan]. | Nihon rinsho. Japanese journal of clinical medicine 20110601 |
Anti-neuroinflammatory effects of psychopharmaceuticals: further than monoamine modulators. | Mini reviews in medicinal chemistry 20110601 |
[Analysis of 76 patients with urticaria and angioedema induced by non-steroidal anti-inflammatory drugs (NSAIDs) in Japan]. | Arerugi = [Allergy] 20110601 |
Combined valproic acid and celecoxib treatment induced synergistic cytotoxicity and apoptosis in neuroblastoma cells. | Anticancer research 20110601 |
(3aR,6S,7aR)-7a-Bromo-2-methyl-sulfonyl-1,2,3,6,7,7a-hexa-hydro-3a,6-ep-oxy-isoindole. | Acta crystallographica. Section E, Structure reports online 20110601 |
[Effect of IFN-α combining with celecoxib on K562/A02 cells proliferation and its mechanism]. | Zhonghua xue ye xue za zhi = Zhonghua xueyexue zazhi 20110601 |
Antibiotic treatment with ampicillin accelerates the healing of colonic damage impaired by aspirin and coxib in the experimental colitis. Importance of intestinal bacteria, colonic microcirculation and proinflammatory cytokines. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20110601 |
Kainic Acid-induced neurotoxicity: targeting glial responses and glia-derived cytokines. | Current neuropharmacology 20110601 |
Correction of endothelial dysfunction in patients with arterial hypertension. | Bulletin of experimental biology and medicine 20110601 |
Human cyclooxygenase-2 is a sequence homodimer that functions as a conformational heterodimer. | The Journal of biological chemistry 20110527 |
Divergent C-H functionalizations directed by sulfonamide pharmacophores: late-stage diversification as a tool for drug discovery. | Journal of the American Chemical Society 20110511 |
A simple QM/MM approach for capturing polarization effects in protein-ligand binding free energy calculations. | The journal of physical chemistry. B 20110505 |
Tramadol hydrochloride extended-release once-daily in the treatment of osteoarthritis of the knee and/or hip: a double-blind, randomized, dose-ranging trial. | American journal of therapeutics 20110501 |
The appropriate use of non-steroidal anti-inflammatory drugs in rheumatic disease: opinions of a multidisciplinary European expert panel. | Annals of the rheumatic diseases 20110501 |
Multi-parametric assessment of the anti-angiogenic effects of liposomal glucocorticoids. | Angiogenesis 20110501 |
Bone metabolism and quality-of-life of postmenopausal women with invasive breast cancer receiving neoadjuvant hormonal therapy: sub-analyses from celecoxib anti-aromatase neoadjuvant (CAAN) trial. | The Journal of steroid biochemistry and molecular biology 20110501 |
Effects of intervention with sulindac and inulin/VSL#3 on mucosal and luminal factors in the pouch of patients with familial adenomatous polyposis. | International journal of colorectal disease 20110501 |
Paracetamol reduces influenza-induced immunopathology in a mouse model of infection without compromising virus clearance or the generation of protective immunity. | Thorax 20110501 |
Roles of prostaglandin E2-EP3/EP4 receptor signaling in the enhancement of lymphangiogenesis during fibroblast growth factor-2-induced granulation formation. | Arteriosclerosis, thrombosis, and vascular biology 20110501 |
Enhancement of photodynamic therapy by 2,5-dimethyl celecoxib, a non-cyclooxygenase-2 inhibitor analog of celecoxib. | Cancer letters 20110501 |
Interaction between adipose tissue stromal cells and gastric cancer cells in vitro. | Cell and tissue research 20110501 |
Synthesis, anti-inflammatory activity and COX-1/COX-2 inhibition of novel substituted cyclic imides. Part 1: Molecular docking study. | European journal of medicinal chemistry 20110501 |
The potential of celecoxib-loaded hydroxyapatite-chitosan nanocomposite for the treatment of colon cancer. | Biomaterials 20110501 |
Sunitinib in relapsed or refractory diffuse large B-cell lymphoma: a clinical and pharmacodynamic phase II multicenter study of the NCIC Clinical Trials Group. | Leukemia & lymphoma 20110501 |
Efficient sequential synthesis of PET Probes of the COX-2 inhibitor [11C]celecoxib and its major metabolite [11C]SC-62807 and in vivo PET evaluation. | Bioorganic & medicinal chemistry 20110501 |
Arsenic trioxide inhibits invasion/migration in SGC-7901 cells by activating the reactive oxygen species-dependent cyclooxygenase-2/matrix metalloproteinase-2 pathway. | Experimental biology and medicine (Maywood, N.J.) 20110501 |
Aspirin and familial adenomatous polyposis: coming full circle. | Cancer prevention research (Philadelphia, Pa.) 20110501 |
Evaluation of gastrointestinal injury and blood flow of small bowel during low-dose aspirin administration. | Journal of clinical biochemistry and nutrition 20110501 |
Study on cow ghee versus soybean oil on 7,12-dimethylbenz(a)-anthracene induced mammary carcinogenesis & expression of cyclooxygenase-2 & peroxisome proliferators activated receptor-γ in rats. | The Indian journal of medical research 20110501 |
[Effect of combination of taxol and celecoxib on reversing multidrug resistance human breast cancer cells (MCF-7/ Taxol) and explore its underlying mechanism]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20110501 |
Synthesis and structure-activity relationship studies of urea-containing pyrazoles as dual inhibitors of cyclooxygenase-2 and soluble epoxide hydrolase. | Journal of medicinal chemistry 20110428 |
Suppressing inflammatory cascade by cyclo-oxygenase inhibitors attenuates quinolinic acid induced Huntington's disease-like alterations in rats. | Life sciences 20110425 |
[Effect of cycloxygenase 2 inhibitor on levels of prostaglandin E2 in plasma and in local infiltrated fluid after functional endoscopic sinus surgery]. | Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20110418 |
Celecoxib inhibits STAT3 phosphorylation and suppresses cell migration and colony forming ability in rhabdomyosarcoma cells. | Biochemical and biophysical research communications 20110415 |
Microsomal prostaglandin E synthase-1 enhances bone cancer growth and bone cancer-related pain behaviors in mice. | Life sciences 20110411 |
An straightforward entry to new pyrazolo-fused dibenzo[1,4]diazepines. | Organic & biomolecular chemistry 20110407 |
High-dose ketorolac affects adult spinal fusion: a meta-analysis of the effect of perioperative nonsteroidal anti-inflammatory drugs on spinal fusion. | Spine 20110401 |
Combination of 6-thioguanine, capecitabine, and celecoxib with temozolomide or lomustine for recurrent high-grade glioma. | Journal of neuro-oncology 20110401 |
A novel COX-2 inhibitor pyrazole derivative proven effective as an anti-inflammatory and analgesic drug. | Basic & clinical pharmacology & toxicology 20110401 |
Antiproliferative effects of COX-2 inhibitor celecoxib on human breast cancer cell lines. | Molecular and cellular biochemistry 20110401 |
'War and Peace' with Barrett's esophagus. | Digestive diseases and sciences 20110401 |
Multimodal analgesic approach incorporating paravertebral blocks for open radical retropubic prostatectomy: a randomized double-blind placebo-controlled study. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20110401 |
Potential molecular targets in chemopreventative action of celecoxib: a proteomics analysis of J774.A1 macrophage-like cell line. | Molecular bioSystems 20110401 |
COX-2 blockade suppresses gliomagenesis by inhibiting myeloid-derived suppressor cells. | Cancer research 20110401 |
Cyclooxygenase 2 promotes parathyroid hyperplasia in ESRD. | Journal of the American Society of Nephrology : JASN 20110401 |
Inhibition of highly pathogenic avian H5N1 influenza virus propagation by RNA oligonucleotides targeting the PB2 gene in combination with celecoxib. | The journal of gene medicine 20110401 |
Prescription pattern of NSAIDs and the prevalence of NSAID-induced gastrointestinal risk factors of orthopaedic patients in clinical practice in Korea. | Journal of Korean medical science 20110401 |
Newer molecules in the treatment of schizophrenia: A clinical update. | Indian journal of pharmacology 20110401 |
Effect of Phellodendron amurense in protecting human osteoarthritic cartilage and chondrocytes. | Journal of ethnopharmacology 20110324 |
Chemoprevention: First line of defence. | Nature 20110324 |
Accelerated drug approval: FDA may get tougher; companies cite hurdles. | Journal of the National Cancer Institute 20110316 |
Maturation and fertilization of nonhuman primate oocytes are compromised by oral administration of a cyclooxygenase-2 inhibitor. | Fertility and sterility 20110315 |
Syntheses and characterization of nimesulide derivatives for dual enzyme inhibitors of both cyclooxygenase-1/2 and 5-lipoxygenase. | Bioorganic & medicinal chemistry 20110315 |
A rat model of bone inflammation-induced pain by intra-tibial complete Freund's adjuvant injection. | Neuroscience letters 20110303 |
Finding drugs against CD133+ glioma subpopulations. | Journal of neurosurgery 20110301 |
Celecoxib and radioresistant glioblastoma-derived CD133+ cells: improvement in radiotherapeutic effects. Laboratory investigation. | Journal of neurosurgery 20110301 |
Value of information in the osteoarthritis setting: cost effectiveness of COX-2 selective inhibitors, traditional NSAIDs and proton pump inhibitors. | PharmacoEconomics 20110301 |
Effects of non-steroidal anti-inflammatory drugs on proliferation, differentiation and migration in equine mesenchymal stem cells. | Cell biology international 20110301 |
Cyclooxygenase-2 inhibitor blocks the production of West Nile virus-induced neuroinflammatory markers in astrocytes. | The Journal of general virology 20110301 |
Celecoxib antagonizes the cytotoxicity of cisplatin in human esophageal squamous cell carcinoma cells by reducing intracellular cisplatin accumulation. | Molecular pharmacology 20110301 |
HuR keeps an angiogenic switch on by stabilising mRNA of VEGF and COX-2 in tumour endothelium. | British journal of cancer 20110301 |
Investigations on cytotoxicity and anti-inflammatory potency of licofelone derivatives. | European journal of medicinal chemistry 20110301 |
Naproxen/esomeprazole fixed-dose combination: for the treatment of arthritic symptoms and to reduce the risk of gastric ulcers. | Drugs & aging 20110301 |
Predictors of response to cyclo-oxygenase-2 inhibitors in osteoarthritis: pooled results from two identical trials comparing etoricoxib, celecoxib, and placebo. | Pain medicine (Malden, Mass.) 20110301 |
Pharmacokinetics of a combination of Δ9-tetrahydro-cannabinol and celecoxib in a porcine model of hemorrhagic shock. | Biopharmaceutics & drug disposition 20110301 |
Mitochondrial disorders in NSAIDs-induced small bowel injury. | Journal of clinical biochemistry and nutrition 20110301 |
Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health. | Oncotarget 20110301 |
Diagnosis and treatment of degenerative joint disease in a captive male chimpanzee (Pan troglodytes). | Journal of the American Association for Laboratory Animal Science : JAALAS 20110301 |
Inflammation in depression: is adiposity a cause? | Dialogues in clinical neuroscience 20110301 |
Rat model of lumbar facet joint osteoarthritis associated with facet-mediated mechanical hyperalgesia induced by intra-articular injection of monosodium iodoacetate. | Journal of the Formosan Medical Association = Taiwan yi zhi 20110301 |
Phase I/II trial of a COX-2 inhibitor with limited field radiation for intermediate prognosis patients who have locally advanced non-small-cell lung cancer: radiation therapy oncology group 0213. | Clinical lung cancer 20110301 |
Decisions that put patients at risk. | Prescrire international 20110301 |
Analysis of Relationship between Levofloxacin and Corrected QT Prolongation Using a Clinical Data Warehouse. | Healthcare informatics research 20110301 |
Bioactive compounds from the fern Lepisorus contortus. | Journal of natural products 20110225 |
Cannabinoid system and cyclooxygenases inhibitors. | Journal of medicine and life 20110215 |
Potential role of cyclooxygenase-2 on the regulation of the drug efflux transporter ABCG2 in breast cancer cell lines. | Journal of cancer research and clinical oncology 20110201 |
Role of capsaicin-sensitive primary afferent neurons and non-protein sulphydryl groups on gastroprotective effect of amifostine against ethanol-induced gastric damage in rats. | Digestive diseases and sciences 20110201 |
Selective cyclooxygenase-2 (COX-2) inhibitors and breast cancer risk. | Breast (Edinburgh, Scotland) 20110201 |
ASAS recommendations for collecting, analysing and reporting NSAID intake in clinical trials/epidemiological studies in axial spondyloarthritis. | Annals of the rheumatic diseases 20110201 |
Evaluation of the role of oxidative stress in chemopreventive action of fish oil and celecoxib in the initiation phase of 7,12-dimethyl benz(α)anthracene-induced mammary carcinogenesis. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20110201 |
Cyclooxygenase 2 plays a role in Emdogain-induced proliferation. | Journal of periodontal research 20110201 |
Interleukin-17A induces cathepsin K and MMP-9 expression in osteoclasts via celecoxib-blocked prostaglandin E2 in osteoblasts. | Biochimie 20110201 |
Pharmacological characterization of KLYP961, a dual inhibitor of inducible and neuronal nitric-oxide synthases. | The Journal of pharmacology and experimental therapeutics 20110201 |
Further qualification of a therapeutic responder index for patients with chronic low back pain. | The Journal of rheumatology 20110201 |
Prostaglandin E₂ signaling and bacterial infection recruit tumor-promoting macrophages to mouse gastric tumors. | Gastroenterology 20110201 |
Phase II trial of Uracil/Tegafur plus leucovorin and celecoxib combined with radiotherapy in locally advanced pancreatic cancer. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20110201 |
Use of nonsteroidal antiinflammatory drugs: is there a change in patient risk profile after withdrawal of rofecoxib? | The Journal of rheumatology 20110201 |
Persistence with non-selective NSAIDs and celecoxib among patients with gastroesophageal reflux disease and osteoarthritis or rheumatoid arthritis. | Current medical research and opinion 20110201 |
The effects of oral ibuprofen and celecoxib in preventing pain, improving recovery outcomes and patient satisfaction after ambulatory surgery. | Anesthesia and analgesia 20110201 |
Celecoxib induces heme oxygenase-1 expression in macrophages and vascular smooth muscle cells via ROS-dependent signaling pathway. | Naunyn-Schmiedeberg's archives of pharmacology 20110201 |
COX-2 inhibition and inhibition of cytosolic phospholipase A2 increase CD36 expression and foam cell formation in THP-1 cells. | Lipids 20110201 |
New cancer treatment strategy using combination of green tea catechins and anticancer drugs. | Cancer science 20110201 |
Effect of Helicobacter pylori infection on Barrett's esophagus and esophageal adenocarcinoma formation in a rat model of chronic gastroesophageal reflux. | Helicobacter 20110201 |
Celecoxib impairs heart development via inhibiting cyclooxygenase-2 activity in zebrafish embryos. | Anesthesiology 20110201 |
A new β-carbonic anhydrase from Brucella suis, its cloning, characterization, and inhibition with sulfonamides and sulfamates, leading to impaired pathogen growth. | Bioorganic & medicinal chemistry 20110201 |
Inhibition of Nox2 oxidase activity ameliorates influenza A virus-induced lung inflammation. | PLoS pathogens 20110201 |
Effect of celecoxib on the antihypertensive effect of losartan in a rat model of renovascular hypertension. | Canadian journal of physiology and pharmacology 20110201 |
Effects of celecoxib in young rats: histopathological changes in tissues and alterations of oxidative stress/antioxidant defense system. | Archives of pharmacal research 20110201 |
p73 as a pharmaceutical target for cancer therapy. | Current pharmaceutical design 20110201 |
Role of nitric oxide-synthase and cyclooxygenase/lipooxygenase systems in development of experimental ulcerative colitis. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20110201 |
Nitric oxide (NO)-releasing aspirin exhibits a potent esophagoprotection in experimental model of acute reflux esophagitis. Role of nitric oxide and proinflammatory cytokines. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20110201 |
A double-blind, randomized, multicentric, placebo-controlled clinical trial of antarth, a phytomedicine, in the treatment of osteoarthritis. | Indian journal of pharmacology 20110201 |
[Effect of celecoxib on pulmonary hypertension of chronic hypoxia and hypercapnic rats]. | Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology 20110201 |
Increased 5α-reductase type 2 expression in human breast carcinoma following aromatase inhibitor therapy: the correlation with decreased tumor cell proliferation. | Hormones & cancer 20110201 |
ACP Journal Club. Celecoxib reduced GI events more than diclofenac plus omeprazole in patients with osteoarthritis or rheumatoid arthritis. | Annals of internal medicine 20110118 |
Arzanol, a prenylated heterodimeric phloroglucinyl pyrone, inhibits eicosanoid biosynthesis and exhibits anti-inflammatory efficacy in vivo. | Biochemical pharmacology 20110115 |
Gender-based effect of statins on functional decline in amyotrophic lateral sclerosis. | Journal of the neurological sciences 20110115 |
Carbonic anhydrase inhibitors. Inhibition studies with anions and sulfonamides of a new cytosolic enzyme from the scleractinian coral Stylophora pistillata. | Bioorganic & medicinal chemistry letters 20110115 |
Measurement of cyclooxygenase inhibition using liquid chromatography-tandem mass spectrometry. | Journal of pharmaceutical and biomedical analysis 20110105 |
Evaluation of management of desmoid tumours associated with familial adenomatous polyposis in Dutch patients. | British journal of cancer 20110104 |
Health-Beneficial Phenolic Aldehyde in Antigonon leptopus Tea. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
Meta-analysis of the related nutritional supplements dimethyl sulfoxide and methylsulfonylmethane in the treatment of osteoarthritis of the knee. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
Aqueous extract of brazilian green propolis: primary components, evaluation of inflammation and wound healing by using subcutaneous implanted sponges. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
Red Mold Rice Mitigates Oral Carcinogenesis in 7,12-Dimethyl-1,2-Benz[a]anthracene-Induced Oral Carcinogenesis in Hamster. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
Preventing chemoresistance of human breast cancer cell line, MCF-7 with celecoxib. | Journal of cancer research and clinical oncology 20110101 |
Antitumoral and antimetastatic effects of metronomic chemotherapy with cyclophosphamide combined with celecoxib on murine mammary adenocarcinomas. | Journal of cancer research and clinical oncology 20110101 |
Antiangiogenic combination therapy after local radiotherapy with topotecan radiosensitizer improved quality of life for children with inoperable brainstem gliomas. | Acta paediatrica (Oslo, Norway : 1992) 20110101 |
Anti-apoptotic Bcl-2 fails to form efficient complexes with pro-apoptotic Bak to protect from Celecoxib-induced apoptosis. | Biochemical pharmacology 20110101 |
Amelioration of cisplatin nephrotoxicity by genetic or pharmacologic blockade of prostaglandin synthesis. | Kidney international 20110101 |
Preclinical evaluation of a gene therapy treatment for transitional cell carcinoma. | Cancer gene therapy 20110101 |
Effects of celecoxib on major prostaglandins in asthma. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20110101 |
The endoplasmic reticulum protein folding factory and its chaperones: new targets for drug discovery? | British journal of pharmacology 20110101 |
Berberine, an isoquinoline alkaloid, inhibits melanoma cancer cell migration by reducing the expressions of cyclooxygenase-2, prostaglandin E₂ and prostaglandin E₂ receptors. | Carcinogenesis 20110101 |
Efficacy and safety of the selective cyclooxygenase-2 inhibitor celecoxib in the treatment of rheumatoid arthritis and osteoarthritis in Japan. | Digestion 20110101 |
Pharmacotherapy of low back pain: targeting nociceptive and neuropathic pain components. | Current medical research and opinion 20110101 |
Induction of a fast inactivation gating on delayed rectifier Shab K(+) channels by the anti-inflammatory drug celecoxib. | Channels (Austin, Tex.) 20110101 |
Gait analysis and pain response of two rodent models of osteoarthritis. | Pharmacology, biochemistry, and behavior 20110101 |
Kainic acid-induced neurodegenerative model: potentials and limitations. | Journal of biomedicine & biotechnology 20110101 |
Current therapeutic approaches in metastatic and recurrent ewing sarcoma. | Sarcoma 20110101 |
Coxibs strike back. | Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 20110101 |
Salvianolic Acid B, a potential chemopreventive agent, for head and neck squamous cell cancer. | Journal of oncology 20110101 |
COX-2 expression in papillary thyroid carcinoma (PTC) in cytological material obtained by fine needle aspiration biopsy (FNAB). | Thyroid research 20110101 |
Aspirin-exacerbated respiratory disease: evaluation and management. | Allergy, asthma & immunology research 20110101 |
A case of chlorpheniramine maleate-induced hypersensitivity with aspirin intolerance. | Allergy, asthma & immunology research 20110101 |
Cyclooxygenase-2 up-regulates vascular endothelial growth factor via a protein kinase C pathway in non-small cell lung cancer. | Journal of experimental & clinical cancer research : CR 20110101 |
Celecoxib can induce vascular endothelial growth factor expression and tumor angiogenesis. | Molecular cancer therapeutics 20110101 |
A human ribonuclease induces apoptosis associated with p21WAF1/CIP1 induction and JNK inactivation. | BMC cancer 20110101 |
The assessment of renal function in relation to the use of drugs in elderly in nursing homes; a cohort study. | BMC geriatrics 20110101 |
Cardiovascular safety of non-steroidal anti-inflammatory drugs: network meta-analysis. | BMJ (Clinical research ed.) 20110101 |
Hyaluronidase recruits mesenchymal-like cells to the lung and ameliorates fibrosis. | Fibrogenesis & tissue repair 20110101 |
α-Tocopheryloxyacetic acid: a novel chemotherapeutic that stimulates the antitumor immune response. | Breast cancer research : BCR 20110101 |
Effects of selective cyclooxygenase-2 and nonselective cyclooxygenase inhibition on myocardial function and perfusion. | Journal of cardiovascular pharmacology 20110101 |
Surmounting chemotherapy and radioresistance in chondrosarcoma: molecular mechanisms and therapeutic targets. | Sarcoma 20110101 |
Celecoxib enhances radiation response of secondary bone tumors of a human non-small cell lung cancer via antiangiogenesis in vivo. | Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] 20110101 |
Selective inhibition of cyclooxygenase-2 suppresses metastatic disease without affecting primary tumor growth in a murine model of Ewing sarcoma. | Journal of pediatric surgery 20110101 |
Animal products, diseases and drugs: a plea for better integration between agricultural sciences, human nutrition and human pharmacology. | Lipids in health and disease 20110101 |
Rodent preclinical models for developing novel antiarthritic molecules: comparative biology and preferred methods for evaluating efficacy. | Journal of biomedicine & biotechnology 20110101 |
Safe administration of celecoxib to a patient with repeated episodes of nephrotic syndrome induced by NSAIDs. | Clinical drug investigation 20110101 |
Animal models of colitis-associated carcinogenesis. | Journal of biomedicine & biotechnology 20110101 |
Use of non-steroidal anti-inflammatory drugs and prostate cancer risk: a population-based nested case-control study. | PloS one 20110101 |
Prostaglandin E2 synthesizing enzymes in rheumatoid arthritis B cells and the effects of B cell depleting therapy on enzyme expression. | PloS one 20110101 |
High-dose enalapril treatment reverses myocardial fibrosis in experimental uremic cardiomyopathy. | PloS one 20110101 |
Reciprocal relationship between APP positioning relative to the membrane and PS1 conformation. | Molecular neurodegeneration 20110101 |
The effect of hypoxia and cycloxygenase inhibitors on nasal polyp derived fibroblasts. | American journal of otolaryngology 20110101 |
Immunotherapy for lung cancers. | Journal of biomedicine & biotechnology 20110101 |
The endotoxin-induced neuroinflammation model of Parkinson's disease. | Parkinson's disease 20110101 |
Experimental trauma models: an update. | Journal of biomedicine & biotechnology 20110101 |
Combined effects of cyclooxygenase-1 and cyclooxygenase-2 selective inhibitors on ovarian carcinoma in vivo. | International journal of molecular sciences 20110101 |
NSAID use selectively increases the risk of non-fatal myocardial infarction: a systematic review of randomised trials and observational studies. | PloS one 20110101 |
RNAi-mediated knockdown of cyclooxygenase2 inhibits the growth, invasion and migration of SaOS2 human osteosarcoma cells: a case control study. | Journal of experimental & clinical cancer research : CR 20110101 |
EGFR and COX-2 protein expression in non-small cell lung cancer and the correlation with clinical features. | Journal of experimental & clinical cancer research : CR 20110101 |
Topical preparations for pain relief: efficacy and patient adherence. | Journal of pain research 20110101 |
Examination of thromboxane synthase as a prognostic factor and therapeutic target in non-small cell lung cancer. | Molecular cancer 20110101 |
'Gut health': a new objective in medicine? | BMC medicine 20110101 |
Chondrosarcoma: with updates on molecular genetics. | Sarcoma 20110101 |
Parkinson's disease and systemic inflammation. | Parkinson's disease 20110101 |
Sex differences in drug disposition. | Journal of biomedicine & biotechnology 20110101 |
Nuclear factor-kappa B activity regulates brain expression of P-glycoprotein in the kainic acid-induced seizure rats. | Mediators of inflammation 20110101 |
Anti-tumor activity of a novel compound-CDF is mediated by regulating miR-21, miR-200, and PTEN in pancreatic cancer. | PloS one 20110101 |
Effect of hookworm infection on wheat challenge in celiac disease--a randomised double-blinded placebo controlled trial. | PloS one 20110101 |
The cyclooxygenase-2 inhibitor celecoxib and alveolar osteitis. | Journal of the Irish Dental Association 20110101 |
Sustained remission of rheumatoid arthritis with a specific serotonin reuptake inhibitor antidepressant: a case report and review of the literature. | Journal of medical case reports 20110101 |
Apoptotic Cell Death and Inhibition of Wnt/β-Catenin Signaling Pathway in Human Colon Cancer Cells by an Active Fraction (HS7) from Taiwanofungus camphoratus. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
Antitumor activity of Noscapine in combination with Doxorubicin in triple negative breast cancer. | PloS one 20110101 |
Common secondary causes of resistant hypertension and rational for treatment. | International journal of hypertension 20110101 |
Preparation and in vitro evaluation of anti-VCAM-1-Fab'-conjugated liposomes for the targeted delivery of the poorly water-soluble drug celecoxib. | Journal of microencapsulation 20110101 |
Neurovascular dysfunction, inflammation and endothelial activation: implications for the pathogenesis of Alzheimer's disease. | Journal of neuroinflammation 20110101 |
Role of HCV Core gene of genotype 1a and 3a and host gene Cox-2 in HCV-induced pathogenesis. | Virology journal 20110101 |
Role of the kidneys in resistant hypertension. | International journal of hypertension 20110101 |
Osteoarthritis subpopulations and implications for clinical trial design. | Arthritis research & therapy 20110101 |
The cyclooxygenase-2 inhibitor celecoxib attenuates hepatocellular carcinoma growth and c-Met expression in an orthotopic mouse model. | Oncology research 20110101 |
Temporal profiles of age-dependent changes in cytokine mRNA expression and glial cell activation after status epilepticus in postnatal rat hippocampus. | Journal of neuroinflammation 20110101 |
Risk of second primary colorectal cancer among colorectal cancer cases: a population-based analysis. | Journal of carcinogenesis 20110101 |
The AOM/DSS murine model for the study of colon carcinogenesis: From pathways to diagnosis and therapy studies. | Journal of carcinogenesis 20110101 |
Clinical trials update: Tertiary prevention of colorectal cancer. | Journal of carcinogenesis 20110101 |
Prescription patterns and appropriateness of NSAID therapy according to gastrointestinal risk and cardiovascular history in patients with diagnoses of osteoarthritis. | BMC medicine 20110101 |
A novel domperidone hydrogel: preparation, characterization, pharmacokinetic, and pharmacodynamic properties. | Journal of drug delivery 20110101 |
Apoptotic sphingolipid ceramide in cancer therapy. | Journal of lipids 20110101 |
Optimization of the balanced steady state free precession (bSSFP) pulse sequence for magnetic resonance imaging of the mouse prostate at 3T. | PloS one 20110101 |
In vitro permeation and in vivo anti-inflammatory and analgesic properties of nanoscaled emulsions containing ibuprofen for topical delivery. | International journal of nanomedicine 20110101 |
A synergistic antiproliferation effect of curcumin and docosahexaenoic acid in SK-BR-3 breast cancer cells: unique signaling not explained by the effects of either compound alone. | BMC cancer 20110101 |
Etoricoxibium picrate. | Acta crystallographica. Section E, Structure reports online 20110101 |
Increased short-term variability of the QT interval in professional soccer players: possible implications for arrhythmia prediction. | PloS one 20110101 |
Vascular endothelial growth factor receptor-2 couples cyclo-oxygenase-2 with pro-angiogenic actions of leptin on human endothelial cells. | PloS one 20110101 |
Cancer stem cell subsets and their relationships. | Journal of translational medicine 20110101 |
Gene expression following exposure to celecoxib in humans: pathways of inflammation and carcinogenesis are activated in tumors but not normal tissues. | Digestion 20110101 |
Lipoxins, the novel mediators of gastroprotection and gastric adaptation to ulcerogenic action of aspirin. | Current pharmaceutical design 20110101 |
Codeine did not increase analgesic efficacy of coxibs in contrast to that of paracetamol or ibuprofen: isobolographic analysis in mice. | Neuro endocrinology letters 20110101 |
Biological Markers in DCIS and Risk of Breast Recurrence: A Systematic Review. | Journal of Cancer 20110101 |
The effect of combined tocolysis on in vitro uterine contractility in preterm labour. | Advances in medical sciences 20110101 |
Toward an anti-inflammatory strategy for depression. | Frontiers in behavioral neuroscience 20110101 |
Diclofenac epolamine topical patch relieves pain associated with ankle sprain. | Journal of pain research 20110101 |
Create a translational medicine knowledge repository--research downsizing, mergers and increased outsourcing have reduced the depth of in-house translational medicine expertise and institutional memory at many pharmaceutical and biotech companies: how will they avoid relearning old lessons? | Journal of translational medicine 20110101 |
Prostaglandin E(2) binding peptide screened by phage displaying: a new therapeutic strategy in rheumatoid arthritis. | Lipids in health and disease 20110101 |
Beyond DNA binding - a review of the potential mechanisms mediating quinacrine's therapeutic activities in parasitic infections, inflammation, and cancers. | Cell communication and signaling : CCS 20110101 |
Osteopoikilosis: pain as a presenting symptom in three family members. | Clinical medicine insights. Arthritis and musculoskeletal disorders 20110101 |
Two-stage revision surgery with preformed spacers and cementless implants for septic hip arthritis: a prospective, non-randomized cohort study. | BMC infectious diseases 20110101 |
Altered mRNA editing and expression of ionotropic glutamate receptors after kainic acid exposure in cyclooxygenase-2 deficient mice. | PloS one 20110101 |
Using clinical trial data and linked administrative health data to reduce the risk of adverse events associated with the uptake of newly released drugs by older Australians: a model process. | BMC public health 20110101 |
Nanoprodrugs of NSAIDs: Preparation and Characterization of Flufenamic Acid Nanoprodrugs. | Journal of drug delivery 20110101 |
Peripheral inflammation increases the damage in animal models of nigrostriatal dopaminergic neurodegeneration: possible implication in Parkinson's disease incidence. | Parkinson's disease 20110101 |
Do PPAR-Gamma Agonists Have a Future in Parkinson's Disease Therapy? | Parkinson's disease 20110101 |
Combined use of low level laser therapy and cyclooxygenase-2 selective inhibition on skin incisional wound reepithelialization in mice: a preclinical study. | Anais brasileiros de dermatologia 20110101 |
Intraoperative local infiltration analgesia for early analgesia after total hip arthroplasty: a randomized, double-blind, placebo-controlled trial. | Regional anesthesia and pain medicine 20110101 |
Interpreting clinical assays for histone deacetylase inhibitors. | Cancer management and research 20110101 |
Phase II study of the combination carboplatin plus celecoxib in heavily pre-treated recurrent ovarian cancer patients. | BMC cancer 20110101 |
Capecitabine in the management of colorectal cancer. | Cancer management and research 20110101 |
Importance of pre-analytical steps for transcriptome and RT-qPCR analyses in the context of the phase II randomised multicentre trial REMAGUS02 of neoadjuvant chemotherapy in breast cancer patients. | BMC cancer 20110101 |
α-Mangostin extracted from the pericarp of the mangosteen (Garcinia mangostana Linn) reduces tumor growth and lymph node metastasis in an immunocompetent xenograft model of metastatic mammary cancer carrying a p53 mutation. | BMC medicine 20110101 |
Celecoxib attenuates liver steatosis and inflammation in non-alcoholic steatohepatitis induced by high-fat diet in rats. | Molecular medicine reports 20110101 |
Dual roles of immune cells and their factors in cancer development and progression. | International journal of biological sciences 20110101 |
The Bone Niche of Chondrosarcoma: A Sanctuary for Drug Resistance, Tumour Growth and also a Source of New Therapeutic Targets. | Sarcoma 20110101 |
Evaluation of drug-excipient interaction in the formulation of celecoxib tablets. | Acta poloniae pharmaceutica 20110101 |
Cell cycle and aging, morphogenesis, and response to stimuli genes are individualized biomarkers of glioblastoma progression and survival. | BMC medical genomics 20110101 |
Combined parecoxib and I.V. paracetamol provides additional analgesic effect with better postoperative satisfaction in patients undergoing anterior cruciate ligament reconstruction. | Saudi journal of anaesthesia 20110101 |
Early and late postnatal myocardial and vascular changes in a protein restriction rat model of intrauterine growth restriction. | PloS one 20110101 |
Functional characterization of human Cd33+ and Cd11b+ myeloid-derived suppressor cell subsets induced from peripheral blood mononuclear cells co-cultured with a diverse set of human tumor cell lines. | Journal of translational medicine 20110101 |
Feasibility of Predicting MCI/AD Using Neuropsychological Tests and Serum β-Amyloid. | International journal of Alzheimer's disease 20110101 |
Aliskiren: An orally active renin inhibitor. | Journal of pharmacy & bioallied sciences 20110101 |
Hyperforin, an Anti-Inflammatory Constituent from St. John's Wort, Inhibits Microsomal Prostaglandin E(2) Synthase-1 and Suppresses Prostaglandin E(2) Formation in vivo. | Frontiers in pharmacology 20110101 |
Prostacyclin: an inflammatory paradox. | Frontiers in pharmacology 20110101 |
Selective cyclooxygenase-2 inhibitor cross-reactivity in aspirin-exacerbated respiratory disease. | Allergy and asthma proceedings 20110101 |
Efficacy of methylsulfonylmethane supplementation on osteoarthritis of the knee: a randomized controlled study. | BMC complementary and alternative medicine 20110101 |
Metformin poisoning: A complex presentation. | Indian journal of anaesthesia 20110101 |
Defining the role of polyamines in colon carcinogenesis using mouse models. | Journal of carcinogenesis 20110101 |
Perspective: Chemoprevention of colorectal neoplasia: Translating scientific promise into clinical practice. | Journal of carcinogenesis 20110101 |
Therapeutic prevention of colorectal carcinogenesis. | Journal of carcinogenesis 20110101 |
Vasectomy and vasectomy reversal: An update. | Indian journal of urology : IJU : journal of the Urological Society of India 20110101 |
The quest for targeted delivery in colon cancer: mucoadhesive valdecoxib microspheres. | International journal of nanomedicine 20110101 |
Cancer-induced bone pain sequentially activates the ERK/MAPK pathway in different cell types in the rat spinal cord. | Molecular pain 20110101 |
Atlantoaxial subluxation as an early manifestation in an adolescent with undifferentiated spondyloarthritis: a case report and review of the literature. | Journal of medical case reports 20110101 |
A rare retroperitoneal tumor. | Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20110101 |
Ayurveda GCP Guidelines: Need for freedom from RCT ascendancy in favor of whole system approach. | Journal of Ayurveda and integrative medicine 20110101 |
Cause for concern in the use of non-steroidal anti-inflammatory medications in the community--a population-based study. | BMC family practice 20110101 |
Resveratrol inhibits Cdk5 activity through regulation of p35 expression. | Molecular pain 20110101 |
Grape seed proanthocyanidins inhibit melanoma cell invasiveness by reduction of PGE2 synthesis and reversal of epithelial-to-mesenchymal transition. | PloS one 20110101 |
Regulation of bombesin-stimulated cyclooxygenase-2 expression in prostate cancer cells. | BMC molecular biology 20110101 |
Treat ankylosing spondylitis with methazolamide. | International journal of medical sciences 20110101 |
Nonsteroidal anti-inflammatory drug gastropathy: new avenues for safety. | Clinical interventions in aging 20110101 |
Safety aspects and rational use of a naproxen + esomeprazole combination in the treatment of rheumatoid disease. | Drug, healthcare and patient safety 20110101 |
Effect of 5-aminolevulinic acid-based photodynamic therapy via reactive oxygen species in human cholangiocarcinoma cells. | International journal of nanomedicine 20110101 |
Involvement of COX-2/PGE(2) Pathway in the Upregulation of MMP-9 Expression in Pancreatic Cancer. | Gastroenterology research and practice 20110101 |
Leaf Extracts of Calocedrus formosana (Florin) Induce G2/M Cell Cycle Arrest and Apoptosis in Human Bladder Cancer Cells. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
Flavocoxid inhibits phospholipase A2, peroxidase moieties of the cyclooxygenases (COX), and 5-lipoxygenase, modifies COX-2 gene expression, and acts as an antioxidant. | Mediators of inflammation 20110101 |
Glial cells in amyotrophic lateral sclerosis. | Neurology research international 20110101 |
Longitudinal numbers-needed-to-treat (NNT) for achieving various levels of analgesic response and improvement with etoricoxib, naproxen, and placebo in ankylosing spondylitis. | BMC musculoskeletal disorders 20110101 |
Medical research: Is everything all right? | Journal of anaesthesiology, clinical pharmacology 20110101 |
Effect of pretreatment with ketorolac tromethamine on operative pain during periodontal surgery: A case-control study. | Journal of Indian Society of Periodontology 20110101 |
Effects of Gum acacia aqueous extract on the histology of the intestine and enzymes of both the intestine and the pancreas of albino rats treated with Meloxicam. | Pharmacognosy research 20110101 |
Cost-Effectiveness Evaluation of Etoricoxib versus Celecoxib and Nonselective NSAIDs in the Treatment of Ankylosing Spondylitis in Norway. | International journal of rheumatology 20110101 |
Cardiorenal Effects of Newer NSAIDs (Celecoxib) versus Classic NSAIDs (Ibuprofen) in Patients with Arthritis. | Journal of toxicology 20110101 |
Anti-cancer natural products isolated from chinese medicinal herbs. | Chinese medicine 20110101 |
ZLJ-6, a novel COX/5-LOX inhibitor, attenuates TNF-α-induced endothelial E-selectin, ICAM-1 and VCAM-1 expression and monocyte-endothelial interactions via a COX/5-LOX-independent mechanism. | Vascular pharmacology 20110101 |
Bacterial carbonic anhydrases as drug targets: toward novel antibiotics? | Frontiers in pharmacology 20110101 |
Smoking and COX-2 functional polymorphisms interact to increase the risk of gastric cardia adenocarcinoma in Chinese population. | PloS one 20110101 |
Haptenation: chemical reactivity and protein binding. | Journal of allergy 20110101 |
Antiamnesic activity of an ayurvedic formulation chyawanprash in mice. | Evidence-based complementary and alternative medicine : eCAM 20110101 |
A biological pathway linking inflammation and depression: activation of indoleamine 2,3-dioxygenase. | Neuropsychiatric disease and treatment 20110101 |
Evaluation of CYP450 inhibitory effects and steady-state pharmacokinetics of genistein in combination with cholecalciferol and citrated zinc bisglycinate in postmenopausal women. | International journal of women's health 20110101 |
Colon-targeted celecoxib-loaded Eudragit® S100-coated poly-ε-caprolactone microparticles: preparation, characterization and in vivo evaluation in rats. | Drug delivery 20110101 |
A targeted lipidomics approach to the study of eicosanoid release in synovial joints. | Arthritis research & therapy 20110101 |
Molecular simulation of hydroxypropyl-beta-cyclodextrin with hydrophobic selective Cox-II chemopreventive agent using host-guest phenomena. | Acta poloniae pharmaceutica 20110101 |
Characterization of chromosomal instability in murine colitis-associated colorectal cancer. | PloS one 20110101 |
Diclofenac topical solution compared with oral diclofenac: a pooled safety analysis. | Journal of pain research 20110101 |
Spherical harmonics coefficients for ligand-based virtual screening of cyclooxygenase inhibitors. | PloS one 20110101 |
Impact of Celecoxib restrictions in medicare beneficiaries with arthritis. | The American journal of managed care 20110101 |
Drug therapy for hereditary cancers. | Hereditary cancer in clinical practice 20110101 |
Effects of Glucosamine and Chondroitin Sulfate on Cartilage Metabolism in OA: Outlook on Other Nutrient Partners Especially Omega-3 Fatty Acids. | International journal of rheumatology 20110101 |
Autoimmunity in amyotrophic lateral sclerosis: past and present. | Neurology research international 20110101 |
Bioincompatible impact of different peritoneal dialysis fluid components and therapeutic interventions as tested in a rat peritoneal dialysis model. | International journal of nephrology 20110101 |
The cyclooxygenase-2 inhibitor celecoxib and alveolar osteitis (Journal of the Irish Dental Association 2011; 57 (1): 50-53). | Journal of the Irish Dental Association 20110101 |
Peripheral anti-inflammatory effects explain the ginsenosides paradox between poor brain distribution and anti-depression efficacy. | Journal of neuroinflammation 20110101 |
Pulmonary oxidative stress is increased in cyclooxygenase-2 knockdown mice with mild pulmonary hypertension induced by monocrotaline. | PloS one 20110101 |
Morphine use in cancer surgery. | Frontiers in pharmacology 20110101 |
Apoptosis induced by piroxicam plus cisplatin combined treatment is triggered by p21 in mesothelioma. | PloS one 20110101 |
Collagen induced arthritis increases secondary metastasis in MMTV-PyV MT mouse model of mammary cancer. | BMC cancer 20110101 |
Potential applications of curcumin and its novel synthetic analogs and nanotechnology-based formulations in cancer prevention and therapy. | Chinese medicine 20110101 |
Vascular endothelial growth factor regulates melanoma cell adhesion and growth in the bone marrow microenvironment via tumor cyclooxygenase-2. | Journal of translational medicine 20110101 |
Early detection of tumor response by FLT/microPET Imaging in a C26 murine colon carcinoma solid tumor animal model. | Journal of biomedicine & biotechnology 20110101 |
Design, synthesis and biological evaluation of new 5,5-diarylhydantoin derivatives as selective cyclooxygenase-2 inhibitors. | Scientia pharmaceutica 20110101 |
Synthesis of Diarylpyrazoles Containing a Phenylsulphone or Carbonitrile Moiety and their Chalcones as Possible Anti-Inflammatory Agents. | Scientia pharmaceutica 20110101 |
Celecoxib, a selective cyclooxygenase-2 inhibitor, attenuates renal injury in a rat model of Cisplatin-induced nephrotoxicity. | Chemotherapy 20110101 |
Pregabalin in acute and chronic pain. | Journal of anaesthesiology, clinical pharmacology 20110101 |
Osteoarthritis accelerates and exacerbates Alzheimer's disease pathology in mice. | Journal of neuroinflammation 20110101 |
Single dose oral analgesics for acute postoperative pain in adults. | The Cochrane database of systematic reviews 20110101 |
Cell-specific aptamers as emerging therapeutics. | Journal of nucleic acids 20110101 |
Gene expression and biological pathways in tissue of men with prostate cancer in a randomized clinical trial of lycopene and fish oil supplementation. | PloS one 20110101 |
5-α reductase inhibitors and prostate cancer prevention: where do we turn now? | BMC medicine 20110101 |
Combinatorial effect of non-steroidal anti-inflammatory drugs and NF-κB inhibitors in ovarian cancer therapy. | PloS one 20110101 |
Regulation by glycogen synthase kinase-3 of inflammation and T cells in CNS diseases. | Frontiers in molecular neuroscience 20110101 |
Pathobiology and chemoprevention of bladder cancer. | Journal of oncology 20110101 |
Tissue factor, blood coagulation, and beyond: an overview. | International journal of inflammation 20110101 |
Meta-analysis of efficacy and safety of intravenous ferric carboxymaltose (Ferinject) from clinical trial reports and published trial data. | BMC blood disorders 20110101 |
Celecoxib: considerations regarding its potential disease-modifying properties in osteoarthritis. | Arthritis research & therapy 20110101 |
Quality of online pharmacies and websites selling prescription drugs: a systematic review. | Journal of medical Internet research 20110101 |
Skeletal muscle protein metabolism in the elderly: Interventions to counteract the 'anabolic resistance' of ageing. | Nutrition & metabolism 20110101 |
Inhibition of cyclo-oxygenase 2 reduces tumor metastasis and inflammatory signaling during blockade of vascular endothelial growth factor. | Vascular cell 20110101 |
Targeting KSHV/HHV-8 latency with COX-2 selective inhibitor nimesulide: a potential chemotherapeutic modality for primary effusion lymphoma. | PloS one 20110101 |
Hypertonic stress induces VEGF production in human colon cancer cell line Caco-2: inhibitory role of autocrine PGE₂. | PloS one 20110101 |
Serum NGAL to Clinically Distinguish Cholangiocarcinoma from Benign Biliary Tract Diseases. | International journal of hepatology 20110101 |
Osteoimmunology and osteoporosis. | Arthritis research & therapy 20110101 |
The rat intervertebral disk degeneration pain model: relationships between biological and structural alterations and pain. | Arthritis research & therapy 20110101 |
Optimizing therapeutic efficacy of chemopreventive agents: A critical review of delivery strategies in oral cancer chemoprevention clinical trials. | Journal of carcinogenesis 20110101 |
Fabrication, modeling and characterization of multi-crosslinked methacrylate copolymeric nanoparticles for oral drug delivery. | International journal of molecular sciences 20110101 |
Non-steroidal anti-inflammatory drug (NSAID) related inhibition of aldosterone glucuronidation and arterial dysfunction in patients with rheumatoid arthritis: a cross-sectional clinical study. | BMJ open 20110101 |
Complex regional pain syndrome. | Indian journal of plastic surgery : official publication of the Association of Plastic Surgeons of India 20110101 |
Buccal mucosa urethroplasty for adult urethral strictures. | Indian journal of urology : IJU : journal of the Urological Society of India 20110101 |
Green tea catechins reduce invasive potential of human melanoma cells by targeting COX-2, PGE2 receptors and epithelial-to-mesenchymal transition. | PloS one 20110101 |
Anti-inflammatory effects of fermented and non-fermented Sophora flavescens: a comparative study. | BMC complementary and alternative medicine 20110101 |
Drug discovery for Duchenne muscular dystrophy via utrophin promoter activation screening. | PloS one 20110101 |
Viscum album exerts anti-inflammatory effect by selectively inhibiting cytokine-induced expression of cyclooxygenase-2. | PloS one 20110101 |
Inhibition of HERG potassium channels by celecoxib and its mechanism. | PloS one 20110101 |
The vitamin E analog, alpha-tocopheryloxyacetic acid enhances the anti-tumor activity of trastuzumab against HER2/neu-expressing breast cancer. | BMC cancer 20110101 |
HMGA1 drives stem cell, inflammatory pathway, and cell cycle progression genes during lymphoid tumorigenesis. | BMC genomics 20110101 |
Nucleus caudalis lesioning: Case report of chronic traumatic headache relief. | Surgical neurology international 20110101 |
Lumiracoxib for acute postoperative dental pain: a systematic review of randomized clinical trials. | Sao Paulo medical journal = Revista paulista de medicina 20110101 |
Altered membrane lipid dynamics and chemoprevention by non-steroidal anti inflammatory drugs during colon carcinogenesis. | Nutricion hospitalaria 20110101 |
In situ formation of nanocrystals from a self-microemulsifying drug delivery system to enhance oral bioavailability of fenofibrate. | International journal of nanomedicine 20110101 |
Exemestane in the adjuvant treatment of breast cancer in postmenopausal women. | Breast cancer : basic and clinical research 20110101 |
Treatment with etanercept in a patient with rheumatoid arthritis-associated interstitial lung disease. | Clinical medicine insights. Case reports 20110101 |
Efficacy and Safety of COX-2 Inhibitors in the Clinical Management of Arthritis: Mini Review. | ISRN pharmacology 20110101 |
Acupuncture as analgesia for low back pain, ankle sprain and migraine in emergency departments: study protocol for a randomized controlled trial. | Trials 20110101 |
Pathway profiling and rational trial design for studies in advanced stage cervical carcinoma: a review and a perspective. | ISRN oncology 20110101 |
Low intracellular ATP levels exacerbate carcinogen-induced inflammatory stress response and inhibit in vitro tubulogenesis in human brain endothelial cells. | Journal of inflammation research 20110101 |
Systematic analyses of genes associated with radiosensitizing effect by celecoxib, a specific cyclooxygenase-2 inhibitor. | Journal of radiation research 20110101 |
Metachronous merkel cell carcinoma: a case report. | Case reports in dermatology 20110101 |
Paracetamol and the placebo effect in osteoarthritis trials: a missing link? | Pain research and treatment 20110101 |
A randomised feasibility study of EPA and Cox-2 inhibitor (Celebrex) versus EPA, Cox-2 inhibitor (Celebrex), resistance training followed by ingestion of essential amino acids high in leucine in NSCLC cachectic patients--ACCeRT study. | BMC cancer 20110101 |
Why we need easy access to all data from all clinical trials and how to accomplish it. | Trials 20110101 |
Preparation of polylactide-co-glycolide nanoparticles incorporating celecoxib and their antitumor activity against brain tumor cells. | International journal of nanomedicine 20110101 |
An observational study of the discrediting of COX-2 NSAIDs in Australia: Vioxx or class effect? | BMC public health 20110101 |
Virtual screening of 2,3-disubstituted-4(3H)-quinazolinones possessing benzenesulfonamide moiety for COX-2 inhibitor. | Bioinformation 20110101 |
Obesity, inflammation, and postmenopausal breast cancer: therapeutic implications. | TheScientificWorldJournal 20110101 |
The promise of neuroprotective agents in Parkinson's disease. | Frontiers in neurology 20110101 |
Bridging health technology assessment (HTA) with multicriteria decision analyses (MCDA): field testing of the EVIDEM framework for coverage decisions by a public payer in Canada. | BMC health services research 20110101 |
Potential Therapeutic Roles for Inhibition of the PI3K/Akt/mTOR Pathway in the Pathophysiology of Diabetic Retinopathy. | Journal of ophthalmology 20110101 |
The haematopoietic stem cell niche: new insights into the mechanisms regulating haematopoietic stem cell behaviour. | Stem cells international 20110101 |
Comparison of published orthopaedic trauma trials following registration in Clinicaltrials.gov. | BMC musculoskeletal disorders 20110101 |
[Bringing evidence to practice: obstacles and barriers]. | Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen 20110101 |
Enhanced bioavailability of sirolimus via preparation of solid dispersion nanoparticles using a supercritical antisolvent process. | International journal of nanomedicine 20110101 |
Tumor cells and tumor-associated macrophages: secreted proteins as potential targets for therapy. | Clinical & developmental immunology 20110101 |
Alzheimer's - Looking beyond plaques. | F1000 medicine reports 20110101 |
Optimal management of Barrett's esophagus: pharmacologic, endoscopic, and surgical interventions. | Therapeutics and clinical risk management 20110101 |
Mining relational paths in integrated biomedical data. | PloS one 20110101 |
Protein kinase A antagonist inhibits β-catenin nuclear translocation, c-Myc and COX-2 expression and tumor promotion in Apc(Min/+) mice. | Molecular cancer 20110101 |
The utility of Aspirin in Dukes C and High Risk Dukes B Colorectal cancer--the ASCOLT study: study protocol for a randomized controlled trial. | Trials 20110101 |
Identification and manipulation of tumor associated macrophages in human cancers. | Journal of translational medicine 20110101 |
Cannabinoid CB2 receptors contribute to upregulation of β-endorphin in inflamed skin tissues by electroacupuncture. | Molecular pain 20110101 |
Chemopreventive effects of NSAIDs on cytokines and transcription factors during the early stages of colorectal cancer. | Pharmacological reports : PR 20110101 |
Apoptosis induction and tumor cell repopulation: the yin and yang of radiotherapy. | Radiation oncology (London, England) 20110101 |
Effects on muscle performance of NSAID treatment with piroxicam versus placebo in geriatric patients with acute infection-induced inflammation. A double blind randomized controlled trial. | BMC musculoskeletal disorders 20110101 |
Differential effects of pravastatin and simvastatin on the growth of tumor cells from different organ sites. | PloS one 20110101 |
Pharmacokinetic evaluation of Paclitaxel in South Indian cancer patients: a prospective study. | Journal of young pharmacists : JYP 20110101 |
Dietary phytochemicals, HDAC inhibition, and DNA damage/repair defects in cancer cells. | Clinical epigenetics 20110101 |
Alzheimer's Disease: APP, Gamma Secretase, APOE, CLU, CR1, PICALM, ABCA7, BIN1, CD2AP, CD33, EPHA1, and MS4A2, and Their Relationships with Herpes Simplex, C. Pneumoniae, Other Suspect Pathogens, and the Immune System. | International journal of Alzheimer's disease 20110101 |
Efficacy and safety of concurrent chemoradiation with weekly cisplatin ± low-dose celecoxib in locally advanced undifferentiated nasopharyngeal carcinoma: a phase II-III clinical trial. | Journal of cancer research and therapeutics 20110101 |
Fernblock, a nutriceutical with photoprotective properties and potential preventive agent for skin photoaging and photoinduced skin cancers. | International journal of molecular sciences 20110101 |
Systematic review of herbals as potential anti-inflammatory agents: Recent advances, current clinical status and future perspectives. | Pharmacognosy reviews 20110101 |
Observation of curative efficacy and prognosis following combination chemotherapy with celecoxib in the treatment of advanced colorectal cancer. | The Journal of international medical research 20110101 |
Pain in blood cancers. | Indian journal of palliative care 20110101 |
Acute generalized exanthematous pustulosis-like, folliculitic drug reaction pattern caused by celecoxib. | Dermatologic therapy 20110101 |
A novel potent tumour promoter aberrantly overexpressed in most human cancers. | Scientific reports 20110101 |
Drug-target network in myocardial infarction reveals multiple side effects of unrelated drugs. | Scientific reports 20110101 |
Overexpression of COX-2 in oral squamous cell carcinoma patients undergoing chemoradiotherapy. | National journal of maxillofacial surgery 20110101 |
Extended hildebrand solubility approach: satranidazole in mixtures of dioxane and water. | Indian journal of pharmaceutical sciences 20110101 |
Chronic inflammation in cancer development. | Frontiers in immunology 20110101 |
Nonsurgical Management of Severe Osteonecrosis of the Knee in an HIV-Positive Patient: A Case Report. | Case reports in infectious diseases 20110101 |
The effect of Frankincense in the treatment of moderate plaque-induced gingivitis: a double blinded randomized clinical trial. | Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20110101 |
Phase I study of celecoxib with concurrent irinotecan, Cisplatin, and radiation therapy for patients with unresectable locally advanced non-small cell lung cancer. | Frontiers in oncology 20110101 |
Therapeutic targeting of cancer stem cells. | Frontiers in oncology 20110101 |
ERK/ribosomal S6 kinase (RSK) signaling positively regulates death receptor 5 expression through co-activation of CHOP and Elk1. | The Journal of biological chemistry 20101231 |
['Rheumatic pain'. Joint is painfully swollen overnight]. | MMW Fortschritte der Medizin 20101216 |
Chemoprevention, risk reduction, therapeutic prevention, or preventive therapy? | Journal of the National Cancer Institute 20101215 |
Chemoprevention of nonmelanoma skin cancer with celecoxib: a randomized, double-blind, placebo-controlled trial. | Journal of the National Cancer Institute 20101215 |
Increase of core temperature induced by corticotropin-releasing factor and urocortin: a comparative study. | Regulatory peptides 20101210 |
Inhibition of cyclooxygenase-2-dependent survivin mediates decursin-induced apoptosis in human KBM-5 myeloid leukemia cells. | Cancer letters 20101208 |
Synthesis and evaluation of the anti-inflammatory properties of selenium-derivatives of celecoxib. | Chemico-biological interactions 20101205 |
An open-label pilot study evaluating by magnetic resonance imaging the potential for a disease-modifying effect of celecoxib compared to a modelized historical control cohort in the treatment of knee osteoarthritis. | Seminars in arthritis and rheumatism 20101201 |
Continuous low-dose temozolomide and celecoxib in recurrent glioblastoma. | Journal of neuro-oncology 20101201 |
Selective COX-2 inhibition affects fatty acids, but not COX mRNA expression in patients with FAP. | Familial cancer 20101201 |
Are COX-2 inhibitors preferable to combined NSAID and PPI in countries with moderate health service expenditures? | Journal of evaluation in clinical practice 20101201 |
Effect of selective COX-2 inhibitor, celecoxib on adjuvant-induced arthritis model in irradiated rats. | International journal of radiation biology 20101201 |
Activation of ceramide synthase 6 by celecoxib leads to a selective induction of C16:0-ceramide. | Biochemical pharmacology 20101201 |
A predictive ligand-based Bayesian model for human drug-induced liver injury. | Drug metabolism and disposition: the biological fate of chemicals 20101201 |
Celecoxib blocks cardiac Kv1.5, Kv4.3 and Kv7.1 (KCNQ1) channels: effects on cardiac action potentials. | Journal of molecular and cellular cardiology 20101201 |
COX-2 is a novel target in therapy of mycosis fungoides. | Leukemia 20101201 |
Expression and possible role of non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) in the human endometrium and endometriosis. | Human reproduction (Oxford, England) 20101201 |
Synthesis and biological evaluation of some thiazolylpyrazole derivatives as dual anti-inflammatory antimicrobial agents. | European journal of medicinal chemistry 20101201 |
The novel benzopyran class of selective cyclooxygenase-2 inhibitors-part I: the first clinical candidate. | Bioorganic & medicinal chemistry letters 20101201 |
Increased expression of cyclooxygenase-2 is associated with the progression to cirrhosis. | The Korean journal of internal medicine 20101201 |
OSU-03012, a novel celecoxib derivative, induces cell swelling and shortens action potential duration in mouse ventricular cells. | Biomedical research (Tokyo, Japan) 20101201 |
[Effects of celecoxib combined with fluvastatin on tumor growth and cell apoptosis in a xenograft model of hepatocellular carcinoma]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20101201 |
Roles of opioid receptor subtype in the spinal antinociception of selective cyclooxygenase 2 inhibitor. | The Korean journal of pain 20101201 |
[Effect of cyclooxygenase-2 inhibitor on expression of matrix metalloproteinase-2 and invasion of tongue squamous cell carcinoma cell line Tca8113]. | Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20101201 |
Etoricoxib-induced life-threatening hyperkalemia and acute kidney dysfunction against the background of telmisartan and a low sodium diet. | International journal of emergency medicine 20101201 |
Development of a list of potentially inappropriate drugs for the korean elderly using the delphi method. | Healthcare informatics research 20101201 |
Formulation of microemulsion gel systems for transdermal delivery of celecoxib: In vitro permeation, anti-inflammatory activity and skin irritation tests. | Drug discoveries & therapeutics 20101201 |
Role of leukotriene B4 in celecoxib-mediated anticancer effect. | Biochemical and biophysical research communications 20101112 |
Bevacizumab in combination with biweekly capecitabine and irinotecan, as first-line treatment for patients with metastatic colorectal cancer. | British journal of cancer 20101109 |
Mechanism of K(v)2.1 channel inhibition by a selective COX-2 inhibitor SC-791-modification of gating. | Brain research 20101104 |
Evaluation of analgesic efficacy, gastrotoxicity and nephrotoxicity of fixed-dose combinations of nonselective, preferential and selective cyclooxygenase inhibitors with paracetamol in rats. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20101101 |
Celecoxib enhances radiosensitivity in medulloblastoma-derived CD133-positive cells. | Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 20101101 |
Preemptive multimodal pain regimen reduces opioid analgesia for patients undergoing robotic-assisted laparoscopic radical prostatectomy. | Urology 20101101 |
Is the sulphonamide radical in the celecoxib molecule essential for its analgesic activity? | Pharmacological research 20101101 |
Pharmacological modulation by celecoxib of cachexia associated with experimental arthritis and atherosclerosis in rabbits. | British journal of pharmacology 20101101 |
Indomethacin promotes adipogenesis of mesenchymal stem cells through a cyclooxygenase independent mechanism. | Journal of cellular biochemistry 20101101 |
Dimethylcelecoxib inhibits mPGES-1 promoter activity by influencing EGR1 and NF-κB. | Biochemical pharmacology 20101101 |
Celecoxib induces tolerance in a model of peripheral inflammatory pain in rats. | Neuropharmacology 20101101 |
Human skin retention and penetration of a copper tripeptide in vitro as function of skin layer towards anti-inflammatory therapy. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20101101 |
Mechanisms involved in IL-6-induced muscular mechanical hyperalgesia in mice. | Pain 20101101 |
Inhibitive effect of celecoxib on the adhesion and invasion of human tongue squamous carcinoma cells to extracellular matrix via down regulation of MMP-2 expression. | Prostaglandins & other lipid mediators 20101101 |
A phase I factorial design study of dose-dense temozolomide alone and in combination with thalidomide, isotretinoin, and/or celecoxib as postchemoradiation adjuvant therapy for newly diagnosed glioblastoma. | Neuro-oncology 20101101 |
Effects of selective cyclooxygenase-2 and nonselective cyclooxygenase inhibition on ischemic myocardium. | The Journal of thoracic and cardiovascular surgery 20101101 |
COX-2-mediated regulation of VEGF-C in association with lymphangiogenesis and lymph node metastasis in lung cancer. | Anatomical record (Hoboken, N.J. : 2007) 20101101 |
Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. | Bioorganic & medicinal chemistry letters 20101101 |
Use of transgenic mice as models for prostate cancer chemoprevention. | Current molecular medicine 20101101 |
Combination 5-fluorouracil, folinic acid and cisplatin (LV5FU2-CDDP) followed by gemcitabine or the reverse sequence in metastatic pancreatic cancer: final results of a randomised strategic phase III trial (FFCD 0301). | Gut 20101101 |
NS-398 (a selective cyclooxygenase-2 inhibitor) decreases agonist-induced contraction of the human ureter via calcium channel inhibition. | Journal of endourology 20101101 |
Vorinostat synergises with capecitabine through upregulation of thymidine phosphorylase. | British journal of cancer 20101101 |
Using non-steroidal anti-inflammatory drugs in the treatment of depression. | Psychiatria Danubina 20101101 |
Physicochemical characterization and drug-release properties of celecoxib hot-melt extruded glass solutions. | The Journal of pharmacy and pharmacology 20101101 |
Pyrazolobenzotriazinone derivatives as COX inhibitors: synthesis, biological activity, and molecular-modeling studies. | Archiv der Pharmazie 20101101 |
[The expression of hepatitis B virus X protein and cyclooxygenase-2 in hepatitis B virus-related hepatocellular carcinoma: correlation with microangiogenesis and metastasis, and what is the possible mechanism]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20101101 |
[Influence of celecoxib on invasiveness of human high-metastatic nasopharyngeal carcinoma cell line CNE-2Z]. | Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20101101 |
Advances in understanding and treating cardiac cachexia: highlights from the 5th Cachexia Conference. | International journal of cardiology 20101029 |
Molecular dynamics and physical stability of amorphous anti-inflammatory drug: celecoxib. | The journal of physical chemistry. B 20101014 |
Electroacupuncture versus celecoxib for neuropathic pain in rat SNL model. | Neuroscience 20101013 |
The effects of COX-2 inhibitor during osteogenic differentiation of bone marrow-derived human mesenchymal stem cells. | Stem cells and development 20101001 |
Pathological and biochemical effects of therapeutic and supratherapeutic doses of celecoxib in Wistar albino male rats. | Drug and chemical toxicology 20101001 |
Delivery of SAR 1118 to the retina via ophthalmic drops and its effectiveness in a rat streptozotocin (STZ) model of diabetic retinopathy (DR). | Investigative ophthalmology & visual science 20101001 |
The role of NF-κB and PPARγ in experimentally induced colorectal cancer and chemoprevention by cyclooxygenase-2 inhibitors. | Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20101001 |
Are Cox-2 drugs the second line option in indomethacin responsive headaches? | The journal of headache and pain 20101001 |
Celecoxib combined with atorvastatin prevents progression of atherosclerosis. | The Journal of surgical research 20101001 |
COX-2 inhibitor nimesulide analogs are aromatase suppressors in breast cancer cells. | The Journal of steroid biochemistry and molecular biology 20101001 |
ErbB4 promotes cyclooxygenase-2 expression and cell survival in colon epithelial cells. | Laboratory investigation; a journal of technical methods and pathology 20101001 |
Melatonin and celecoxib improve the outcomes in hamsters with experimental pancreatic cancer. | Journal of pineal research 20101001 |
Topical diclofenac epolamine patch 1.3% for treatment of acute pain caused by soft tissue injury. | International journal of clinical practice 20101001 |
Overexpression of COX-2 in celecoxib-resistant breast cancer cell lines. | The Journal of surgical research 20101001 |
Pre-surgical study of the biological effects of the selective cyclo-oxygenase-2 inhibitor celecoxib in patients with primary breast cancer. | Breast cancer research and treatment 20101001 |
Cyclooxygenase-independent inhibitory effects on T cell activation of novel 4,5-dihydro-3 trifluoromethyl pyrazole cyclooxygenase-2 inhibitors. | International immunopharmacology 20101001 |
Celecoxib inhibits cell proliferation through the activation of ERK and p38 MAPK in head and neck squamous cell carcinoma cell lines. | Anti-cancer drugs 20101001 |
Does administration of non-steroidal anti-inflammatory drug determine morphological changes in adrenal cortex: ultrastructural studies. | Protoplasma 20101001 |
Development of an online p38α mitogen-activated protein kinase binding assay and integration of LC-HR-MS. | Analytical and bioanalytical chemistry 20101001 |
Anti-cancer effects of celecoxib on nasopharyngeal carcinoma HNE-1 cells expressing COX-2 oncoprotein. | Cytotechnology 20101001 |
Etiology and outcome of patients with upper gastrointestinal bleeding: a study from South of Iran. | Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20101001 |
Should nonsteroidal anti-inflammatory drugs (NSAIDs) be prescribed to the older adult? | Drugs & aging 20101001 |
Low risk of thromboembolic complications after fast-track hip and knee arthroplasty. | Acta orthopaedica 20101001 |
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery. | Minerva anestesiologica 20101001 |
Are current available therapies disease-modifying in spondyloarthritis? | Best practice & research. Clinical rheumatology 20101001 |
Antiproliferative effects of rapamycin and celecoxib in angiosarcoma cell lines. | Anticancer research 20101001 |
[Effect of celecoxib and adriamycin on proliferation and apoptosis of Raji cells and its mechanism]. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20101001 |
Short-term therapy with celecoxib and lansoprazole modulates Th1/ Th2 immune response in human gastric mucosa. | Helicobacter 20101001 |
Celecoxib mitigates cigarette smoke induced oxidative stress in mice. | Indian journal of biochemistry & biophysics 20101001 |
A molecular signature of normal breast epithelial and stromal cells from Li-Fraumeni syndrome mutation carriers. | Oncotarget 20101001 |
Cyclooxygenase-2 expression and its association with thyroid lesions. | Archives of medical science : AMS 20101001 |
Selective cyclooxygenase-2 silencing mediated by engineered E. coli and RNA interference induces anti-tumour effects in human colon cancer cells. | British journal of cancer 20100928 |
Synthesis, anti-inflammatory activity, and in vitro antitumor effect of a novel class of cyclooxygenase inhibitors: 4-(aryloyl)phenyl methyl sulfones. | Journal of medicinal chemistry 20100923 |
The analgesic and anti-inflammatory effect of WIN-34B, a new herbal formula for osteoarthritis composed of Lonicera japonica Thunb and Anemarrhena asphodeloides BUNGE in vivo. | Journal of ethnopharmacology 20100915 |
Nonsteroidal anti-inflammatory drugs increase TNF production in rheumatoid synovial membrane cultures and whole blood. | Journal of immunology (Baltimore, Md. : 1950) 20100915 |
Cox-2 inhibition attenuates cardiovascular and inflammatory aspects in monosodium glutamate-induced obese rats. | Life sciences 20100911 |
A rapid recovery program: early home and pain free. | Orthopedics 20100907 |
[Comparing the analgesic efficacy of continuous femoral nerve blockade and continuous intravenous analgesia after total knee arthroplasty]. | Zhonghua yi xue za zhi 20100907 |
Celecoxib increases retinoid sensitivity in human colon cancer cell lines. | Cellular & molecular biology letters 20100901 |
Celecoxib, but not rofecoxib or naproxen, attenuates cardiac hypertrophy and fibrosis induced in vitro by angiotensin and aldosterone. | Clinical and experimental pharmacology & physiology 20100901 |
Excess risk of hospital admission for cardiovascular disease within the first 7 years from onset of inflammatory polyarthritis. | Annals of the rheumatic diseases 20100901 |
Overexpression of 5-lipoxygenase in sporadic colonic adenomas and a possible new aspect of colon carcinogenesis. | International journal of colorectal disease 20100901 |
cPLA2 is protective against COX inhibitor-induced intestinal damage. | Toxicological sciences : an official journal of the Society of Toxicology 20100901 |
Antioxidants can inhibit basal autophagy and enhance neurodegeneration in models of polyglutamine disease. | Human molecular genetics 20100901 |
IL-17A stimulates the expression of inflammatory cytokines via celecoxib-blocked prostaglandin in MC3T3-E1 cells. | Archives of oral biology 20100901 |
Targeting the prostaglandin E2 EP1 receptor and cyclooxygenase-2 in the amygdala kindling model in mice. | Epilepsy research 20100901 |
Increased risk of stroke associated with nonsteroidal anti-inflammatory drugs: a nationwide case-crossover study. | Stroke 20100901 |
Discovery and structure-activity relationships of a series of pyroglutamic acid amide antagonists of the P2X7 receptor. | Bioorganic & medicinal chemistry letters 20100901 |
Design, synthesis and biological evaluation of new (E)- and (Z)-1,2,3-triaryl-2-propen-1-ones as selective COX-2 inhibitors. | European journal of medicinal chemistry 20100901 |
Septic versus aseptic hip revision: how different? | Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology 20100901 |
Identifying early prescribers of cycloxygenase-2 inhibitors (COX-2s) in Nova Scotia, Canada: Considerations for targeted academic detailing. | Research in social & administrative pharmacy : RSAP 20100901 |
Antinociceptive Effect of Memantine and Morphine on Vincristine-induced Peripheral Neuropathy in Rats. | The Korean journal of pain 20100901 |
Spontaneous retropharyngeal hematoma - a case report -. | The Korean journal of pain 20100901 |
Loxoprofen Sodium, a Non-Selective NSAID, Reduces Atherosclerosis in Mice by Reducing Inflammation. | Journal of clinical biochemistry and nutrition 20100901 |
Design, synthesis, and biological evaluation of 1,5-diaryl-1,2,4-triazole derivatives as selective cyclooxygenase-2 inhibitors. | Archiv der Pharmazie 20100901 |
[Application and effect of auricular acupoint pressing for analgesia in perioperative period of total knee joint replacement]. | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20100901 |
Abstracts of the 5(th) Cachexia Conference, Barcelona, Spain, December 5-8, 2009. | Journal of cachexia, sarcopenia and muscle 20100901 |
Drug interaction between celecoxib and methotrexate in organic anion transporter 3-transfected renal cells and in rats in vivo. | European journal of pharmacology 20100825 |
Comparison of cyclooxygenase-1 crystal structures: cross-talk between monomers comprising cyclooxygenase-1 homodimers. | Biochemistry 20100824 |
Design, synthesis, and biological evaluation of ketoprofen analogs as potent cyclooxygenase-2 inhibitors. | Bioorganic & medicinal chemistry 20100815 |
Preventive effects of COX-2 inhibitor, celecoxib on renal tubular injury induced by shock wave lithotriptor. | Urological research 20100801 |
Suppression of human lung cancer cell growth and migration by berbamine. | Cytotechnology 20100801 |
Inhibitory effects of norcantharidin against human lung cancer cell growth and migration. | Cytotechnology 20100801 |
Celecoxib enhances the inhibitory effect of cisplatin on Tca8113 cells in human tongue squamous cell carcinoma in vivo and in vitro. | Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20100801 |
Role of COX-2 in nonsteroidal anti-inflammatory drug enteropathy in rodents. | Scandinavian journal of gastroenterology 20100801 |
Anti-inflammatory effects of celecoxib in rat lungs with smoke-induced emphysema. | American journal of physiology. Lung cellular and molecular physiology 20100801 |
Acute pain after total hip arthroplasty does not predict the development of chronic postsurgical pain 6 months later. | Journal of anesthesia 20100801 |
Do the blood pressure effects of nonsteroidal antiinflammatory drugs influence cardiovascular morbidity and mortality? | Current hypertension reports 20100801 |
Antifibrotic and fibrolytic properties of celecoxib in liver damage induced by carbon tetrachloride in the rat. | Liver international : official journal of the International Association for the Study of the Liver 20100801 |
Clinical efficacy and safety of glucosamine, chondroitin sulphate, their combination, celecoxib or placebo taken to treat osteoarthritis of the knee: 2-year results from GAIT. | Annals of the rheumatic diseases 20100801 |
A comparison of the chronic effects of human pharmaceuticals on two cladocerans, Daphnia magna and Ceriodaphnia dubia. | Chemosphere 20100801 |
Celecoxib treatment in an early stage of schizophrenia: results of a randomized, double-blind, placebo-controlled trial of celecoxib augmentation of amisulpride treatment. | Schizophrenia research 20100801 |
Celecoxib prodrugs possessing a diazen-1-ium-1,2-diolate nitric oxide donor moiety: synthesis, biological evaluation and nitric oxide release studies. | Bioorganic & medicinal chemistry letters 20100801 |
Effect of celecoxib combined with thoracic epidural analgesia on pain after thoracotomy. | British journal of anaesthesia 20100801 |
Carbonic anhydrase inhibitors. The X-ray crystal structure of human isoform II in adduct with an adamantyl analogue of acetazolamide resides in a less utilized binding pocket than most hydrophobic inhibitors. | Bioorganic & medicinal chemistry letters 20100801 |
Synthesis and biological evaluation of novel pyrazole compounds. | Bioorganic & medicinal chemistry 20100801 |
Mutation of Phe91 to Asn in human carbonic anhydrase I unexpectedly enhanced both catalytic activity and affinity for sulfonamide inhibitors. | Bioorganic & medicinal chemistry 20100801 |
The inhibitory effect of celecoxib on mouse hepatoma H22 cell line on the arachidonic acid metabolic pathway. | Biochemistry and cell biology = Biochimie et biologie cellulaire 20100801 |
The post-operative analgesic efficacy of celecoxib compared with placebo and parecoxib after total hip or knee arthroplasty. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20100801 |
[High-performance liquid chromatography for determining celecoxib concentration in hamster tongue tissue after oral local application]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20100801 |
1-(3,5-Diethyl-1H-pyrazol-1-yl)-3-phenyl-isoquinoline. | Acta crystallographica. Section E, Structure reports online 20100801 |
Combination chemotherapy for influenza. | Viruses 20100801 |
Treatment strategies for osteoarthritis patients with pain and hypertension. | Therapeutic advances in musculoskeletal disease 20100801 |
NSAIDs and risk of lower gastrointestinal bleeding. | Lancet (London, England) 20100717 |
Celecoxib versus omeprazole and diclofenac in patients with osteoarthritis and rheumatoid arthritis (CONDOR): a randomised trial. | Lancet (London, England) 20100717 |
Synthesis, characterization and preliminary analysis of in vivo biological activity of chitosan/celecoxib microcapsules. | Bioorganic & medicinal chemistry letters 20100715 |
1,5-Diarylimidazoles with strong inhibitory activity against COX-2 catalyzed PGE2 production from LPS-induced RAW 264.7 cells. | Bioorganic & medicinal chemistry letters 20100715 |
Cyclooxygenase inhibitors suppress the expression of P2X(3) receptors in the DRG and attenuate hyperalgesia following chronic constriction injury in rats. | Neuroscience letters 20100705 |
Synthesis and antitumor properties of selenocoxib-1 against rat prostate adenocarcinoma cells. | International journal of cancer 20100701 |
Vascular endothelial growth factor and not cyclooxygenase 2 promotes endothelial cell viability in the pancreatic tumor microenvironment. | Pancreas 20100701 |
Far-distant metastases along the CSF pathway of glioblastoma multiforme during continuous low-dose chemotherapy with temozolomide and celecoxib. | Neurosurgical review 20100701 |
Nanoparticles for local drug delivery to the oral mucosa: proof of principle studies. | Pharmaceutical research 20100701 |
Synergistic effect of celecoxib on TRAIL-induced apoptosis in hepatocellular carcinoma cells. | Cancer investigation 20100701 |
Translocation of cell penetrating peptide engrafted nanoparticles across skin layers. | Biomaterials 20100701 |
A multicenter randomized phase II study of sequential epirubicin/cyclophosphamide followed by docetaxel with or without celecoxib or trastuzumab according to HER2 status, as primary chemotherapy for localized invasive breast cancer patients. | Breast cancer research and treatment 20100701 |
Antitumor effects of inhibitors of nitric oxide synthase or cyclooxygenase-2 on human KB carcinoma cells overexpressing COX-2. | Oncology reports 20100701 |
Preparation and evaluation of celecoxib transdermal patches. | Pakistan journal of pharmaceutical sciences 20100701 |
Analgesic use and the risk for progression of chronic kidney disease. | Pharmacoepidemiology and drug safety 20100701 |
Increased risk of hospitalization for acute hepatitis in patients with previous exposure to NSAIDs. | Pharmacoepidemiology and drug safety 20100701 |
Serum cytokine analysis in a positive chemoprevention trial: selenium, interleukin-2, and an association with squamous preneoplastic disease. | Cancer prevention research (Philadelphia, Pa.) 20100701 |
Celecoxib treatment restores pharmacosensitivity in a rat model of pharmacoresistant epilepsy. | British journal of pharmacology 20100701 |
Apoptotic Effect of Tolfenamic Acid in KB Human Oral Cancer Cells: Possible Involvement of the p38 MAPK Pathway. | Journal of clinical biochemistry and nutrition 20100701 |
Cardiovascular safety of celecoxib on top of dual antiplatelet therapy. | Korean circulation journal 20100701 |
Celecoxib does not attenuate the antiplatelet effects of aspirin and clopidogrel in healthy volunteers. | Korean circulation journal 20100701 |
Incidence and possible risk factors for clinical upper gastrointestinal events in patients taking selective cyclooxygenase-2 inhibitors: A prospective, observational, cohort study in Taiwan. | Clinical therapeutics 20100701 |
Antiproliferative effect of a novel nitro-oxy derivative of celecoxib in human colon cancer cells: role of COX-2 and nitric oxide. | Anticancer research 20100701 |
[Effects of EGFR inhibitor AG1478 in combination with celecoxib on the growth of gastric cancer cells]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20100701 |
Exploiting cyclooxygenase-(in)dependent properties of COX-2 inhibitors for malignant glioma therapy. | Anti-cancer agents in medicinal chemistry 20100701 |
Formation of celecoxib nanoparticles from volatile microemulsions. | International journal of pharmaceutics 20100630 |
Metronomic gemcitabine suppresses tumour growth, improves perfusion, and reduces hypoxia in human pancreatic ductal adenocarcinoma. | British journal of cancer 20100629 |
Effects of treadmill exercise on cyclooxygenase-2 in the hippocampus in type 2 diabetic rats: correlation with the neuroblasts. | Brain research 20100623 |
Peripheral mu-, kappa- and delta-opioid receptors mediate the hypoalgesic effect of celecoxib in a rat model of thermal hyperalgesia. | Life sciences 20100619 |
Protection of Monascus-fermented dioscorea against DMBA-induced oral injury in hamster by anti-inflammatory and antioxidative potentials. | Journal of agricultural and food chemistry 20100609 |
Celecoxib-loaded liposomes: effect of cholesterol on encapsulation and in vitro release characteristics. | Bioscience reports 20100603 |
Anti-inflammatory treatment in AD mice protects against neuronal pathology. | Experimental neurology 20100601 |
Exemestane as first-line therapy in postmenopausal women with recurrent or metastatic breast cancer. | American journal of clinical oncology 20100601 |
Patient-reported-outcomes in subjects with painful lumbar or cervical radiculopathy treated with pregabalin: evidence from medical practice in primary care settings. | Rheumatology international 20100601 |
A phase I study of capecitabine, irinotecan, celecoxib, and radiation as neoadjuvant therapy of patients with locally advanced rectal cancer. | American journal of clinical oncology 20100601 |
Concentration-dependent differing actions of the nonsteroidal anti-inflammatory drug, celecoxib, in distearoyl phosphatidylcholine multilamellar vesicles. | Journal of liposome research 20100601 |
Cyclooxygenase-2 preserves flow-mediated remodelling in old obese Zucker rat mesenteric arteries. | Cardiovascular research 20100601 |
Protective effect of rebamipide against celecoxib-induced gastric mucosal cell apoptosis. | Biochemical pharmacology 20100601 |
Formulation, characterization and pulmonary deposition of nebulized celecoxib encapsulated nanostructured lipid carriers. | Journal of controlled release : official journal of the Controlled Release Society 20100601 |
Rofecoxib, but not celecoxib, increases the risk of thromboembolic cardiovascular events in young adults-a nationwide registry-based study. | European journal of clinical pharmacology 20100601 |
Variability among nonsteroidal antiinflammatory drugs in risk of upper gastrointestinal bleeding. | Arthritis and rheumatism 20100601 |
Focus on therapy: hemicrania continua and new daily persistent headache. | The journal of headache and pain 20100601 |
Timing of ibuprofen use and bone mineral density adaptations to exercise training. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20100601 |
The safety and efficacy of celecoxib in children with familial adenomatous polyposis. | The American journal of gastroenterology 20100601 |
Cyclooxygenase-derived mediators regulate the immunological control of Strongyloides venezuelensis infection. | FEMS immunology and medical microbiology 20100601 |
Novel anti-inflammatory functions for endothelial and myeloid cyclooxygenase-2 in a new mouse model of Crohn's disease. | American journal of physiology. Gastrointestinal and liver physiology 20100601 |
Renal hyperfiltration is a determinant of endothelial function responses to cyclooxygenase 2 inhibition in type 1 diabetes. | Diabetes care 20100601 |
Chemoprevention strategies for pancreatic cancer. | Nature reviews. Gastroenterology & hepatology 20100601 |
Update on antithrombotic therapy for stroke prevention in atrial fibrillation. | Current treatment options in cardiovascular medicine 20100601 |
A nonhormonal model for emergency contraception: prostaglandin synthesis inhibitor effects on luteal function and lifespan, a pilot study. | Contraception 20100601 |
Celecoxib may decrease some skin cancers. | The Nurse practitioner 20100601 |
Persistent cyclooxygenase-2 inhibition downregulates NF-{kappa}B, resulting in chronic intestinal inflammation in the min/+ mouse model of colon tumorigenesis. | Cancer research 20100601 |
Long-term outcome of adjunctive celecoxib treatment after paclitaxel-eluting stent implantation for the complex coronary lesions: two-year clinical follow-up of COREA-TAXUS trial. | Circulation. Cardiovascular interventions 20100601 |
Combination effects of salvianolic acid B with low-dose celecoxib on inhibition of head and neck squamous cell carcinoma growth in vitro and in vivo. | Cancer prevention research (Philadelphia, Pa.) 20100601 |
Colon carcinoma cell interaction with liver sinusoidal endothelium inhibits organ-specific antitumor immunity through interleukin-1-induced mannose receptor in mice. | Hepatology (Baltimore, Md.) 20100601 |
The effects of paracetamol, ketorolac, and paracetamol plus morphine on pain control after thyroidectomy. | The Korean journal of pain 20100601 |
Activated PI3K/Akt/COX-2 pathway induces resistance to radiation in human cervical cancer HeLa cells. | Cancer biotherapy & radiopharmaceuticals 20100601 |
Chemoprevention of colorectal cancer: systematic review and economic evaluation. | Health technology assessment (Winchester, England) 20100601 |
Neuropathologic and clinical features of human medial temporal lobe epilepsy. | Journal of clinical neurology (Seoul, Korea) 20100601 |
Effect of treatment based on syndrome differentiation by Chinese medicine on post-traumatic elbow arthritis. | Chinese journal of integrative medicine 20100601 |
Antiamnesic effect of stevioside in scopolamine-treated rats. | Indian journal of pharmacology 20100601 |
[Risk of anastomotic leakage in postoperative treatment with non-steroidal anti-inflammatory drugs]. | Ugeskrift for laeger 20100531 |
Colloid formation by drugs in simulated intestinal fluid. | Journal of medicinal chemistry 20100527 |
Wettability and surface chemistry of crystalline and amorphous forms of a poorly water soluble drug. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20100512 |
Microsomal prostaglandin E synthase-1 inhibition blocks proliferation and enhances apoptosis in oesophageal adenocarcinoma cells without affecting endothelial prostacyclin production. | International journal of cancer 20100501 |
Treatment of atypical central neurocytoma in a child with high dose chemotherapy and autologous stem cell rescue. | Journal of neuro-oncology 20100501 |
Synergistic anticancer effects of combined gamma-tocotrienol and celecoxib treatment are associated with suppression in Akt and NFkappaB signaling. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100501 |
Infliximab for the treatment of refractory scleritis. | The British journal of ophthalmology 20100501 |
TLR4-dependent induction of vascular adhesion molecule-1 in rheumatoid arthritis synovial fibroblasts: Roles of cytosolic phospholipase A(2)alpha/cyclooxygenase-2. | Journal of cellular physiology 20100501 |
Delivery of celecoxib for treating diseases of the eye: influence of pigment and diabetes. | Expert opinion on drug delivery 20100501 |
Synthesis of new 2,3-dihydroquinazolin-4(1H)-one derivatives for analgesic and anti-inflammatory evaluation. | Archiv der Pharmazie 20100501 |
Pharmacotherapy for inherited colorectal cancer. | Expert opinion on pharmacotherapy 20100501 |
Statin use and colorectal adenoma risk: results from the adenoma prevention with celecoxib trial. | Cancer prevention research (Philadelphia, Pa.) 20100501 |
Statins and the colorectum: hope for chemoprevention? | Cancer prevention research (Philadelphia, Pa.) 20100501 |
Balancing gastrointestinal benefit-risk in individuals who are prescribed NSAIDs for arthritis. | Rheumatology (Oxford, England) 20100501 |
Patient benefit-risk in arthritis--a rheumatologist's perspective. | Rheumatology (Oxford, England) 20100501 |
Identifying and assessing benefit-risk in primary care--a family physician's perspective. | Rheumatology (Oxford, England) 20100501 |
A review of the gastrointestinal safety data--a gastroenterologist's perspective. | Rheumatology (Oxford, England) 20100501 |
Genomic characterization of the inflammatory response initiated by surgical intervention and the effect of perioperative cyclooxygenase 2 blockade. | The Journal of thoracic and cardiovascular surgery 20100501 |
Effects of short-term celecoxib treatment in patients with invasive transitional cell carcinoma of the urinary bladder. | Molecular cancer therapeutics 20100501 |
Progression from chronic atrophic gastritis to gastric cancer; tangle, toggle, tackle with Korea red ginseng. | Journal of clinical biochemistry and nutrition 20100501 |
Deciphering diseases and biological targets for environmental chemicals using toxicogenomics networks. | PLoS computational biology 20100501 |
The effects of lumiracoxib 100 mg once daily vs. ibuprofen 600 mg three times daily on the blood pressure profiles of hypertensive osteoarthritis patients taking different classes of antihypertensive agents. | International journal of clinical practice 20100501 |
Incidence of gastroduodenal ulcers during treatment with celecoxib or diclofenac: pooled results from three 12-week trials in Chinese patients with osteoarthritis or rheumatoid arthritis. | International journal of rheumatic diseases 20100501 |
Diffuse rash and cough in elderly woman with a UTI. | The Journal of family practice 20100501 |
Metronomic cyclophosphamide in elderly patients with advanced, castration-resistant prostate cancer. | Journal of the American Geriatrics Society 20100501 |
Inflammatory pathogenesis of prostate cancer and celecoxib. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20100420 |
Celecoxib activates PI-3K/Akt and mitochondrial redox signaling to enhance heme oxygenase-1-mediated anti-inflammatory activity in vascular endothelium. | Free radical biology & medicine 20100415 |
Megestrol acetate versus metronomic cyclophosphamide in patients having exhausted all effective therapies under standard care. | British journal of cancer 20100413 |
Silica nanoparticles to control the lipase-mediated digestion of lipid-based oral delivery systems. | Molecular pharmaceutics 20100405 |
Celecoxib inhibits MDR1 expression through COX-2-dependent mechanism in human hepatocellular carcinoma (HepG2) cell line. | Cancer chemotherapy and pharmacology 20100401 |
Single circulating tumor cell detection and overall survival in nonmetastatic breast cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20100401 |
Biotransformation of celecoxib using microbial cultures. | Applied biochemistry and biotechnology 20100401 |
Effect of AEE788 and/or Celecoxib on colon cancer cell morphology using advanced microscopic techniques. | Micron (Oxford, England : 1993) 20100401 |
Compressive force induces osteoclast differentiation via prostaglandin E(2) production in MC3T3-E1 cells. | Connective tissue research 20100401 |
Prostaglandin E2 prevents Helicobacter-induced gastric preneoplasia and facilitates persistent infection in a mouse model. | Gastroenterology 20100401 |
A phase 2 pilot trial of low-dose, continuous infusion, or 'metronomic' paclitaxel and oral celecoxib in patients with metastatic melanoma. | Cancer 20100401 |
Celecoxib activates Stat5 and restores or increases the expression of growth hormone-regulated genes in hepatocarcinogenesis. | Anti-cancer drugs 20100401 |
A prospective evaluation of 2 different pain management protocols for total hip arthroplasty. | The Journal of arthroplasty 20100401 |
Dextran carrier macromolecule for colon specific delivery of celecoxib. | Current drug delivery 20100401 |
Hypertrophic cranial pachymeningitis induced by long-term administration of nonsteroidal antiinflammatory drugs. | The Annals of pharmacotherapy 20100401 |
Synthesis and biological evaluation of N-difluoromethyl-1,2-dihydropyrid-2-one acetic acid regioisomers: dual inhibitors of cyclooxygenases and 5-lipoxygenase. | Bioorganic & medicinal chemistry letters 20100401 |
The effects of radix curcumae extract on expressions of VEGF, COX-2 and PCNA in gastric mucosa of rats fed with MNNG. | Current pharmaceutical biotechnology 20100401 |
Phase II trial of gemcitabine, irinotecan, and celecoxib in patients with advanced pancreatic cancer. | Journal of clinical gastroenterology 20100401 |
Novel combination of celecoxib and proteasome inhibitor MG132 provides synergistic antiproliferative and proapoptotic effects in human liver tumor cells. | Cell cycle (Georgetown, Tex.) 20100401 |
Effect of recombinant human epidermal growth factor against cutaneous scar formation in murine full-thickness wound healing. | Journal of Korean medical science 20100401 |
Comparison of the causes and clinical features of drug rash with eosinophilia and systemic symptoms and stevens-johnson syndrome. | Allergy, asthma & immunology research 20100401 |
Nonsteroidal anti-inflammatory therapy and recurrent acute anterior uveitis. | Ocular immunology and inflammation 20100401 |
Chemoprophylaxis in colorectal cancer: current concepts and a practical algorithm for use. | Expert opinion on investigational drugs 20100401 |
[Influence of celecoxib combined with IFN-alpha on proliferation, apoptosis, cell cycle and CD117 expression of K562 cells]. | Zhongguo shi yan xue ye xue za zhi 20100401 |
Cdh11 acts as a tumor suppressor in a murine retinoblastoma model by facilitating tumor cell death. | PLoS genetics 20100401 |
The analgesic and anti-inflammatory effects of 7-oxosandaracopimaric acid isolated from the roots of Aralia cordata. | Archives of pharmacal research 20100401 |
Effect of non-steroidal anti-inflammatory drugs on behavioral actions of diazepam in mice. | Neurosciences (Riyadh, Saudi Arabia) 20100401 |
The PI3K/Akt/FOXO3a/p27Kip1 signaling contributes to anti-inflammatory drug-suppressed proliferation of human osteoblasts. | Biochemical pharmacology 20100315 |
Cloning, characterization, and inhibition studies of a beta-carbonic anhydrase from Brucella suis. | Journal of medicinal chemistry 20100311 |
Rosuvastatin prevents conduit artery endothelial dysfunction induced by ischemia and reperfusion by a cyclooxygenase-2-dependent mechanism. | Journal of the American College of Cardiology 20100309 |
Inhibition of secretion of interleukin (IL)-12/IL-23 family cytokines by 4-trifluoromethyl-celecoxib is coupled to degradation via the endoplasmic reticulum stress protein HERP. | The Journal of biological chemistry 20100305 |
Potential Use of Plectranthus amboinicus in the Treatment of Rheumatoid Arthritis. | Evidence-based complementary and alternative medicine : eCAM 20100301 |
Hematopoietic progenitor kinase 1 is a critical component of prostaglandin E2-mediated suppression of the anti-tumor immune response. | Cancer immunology, immunotherapy : CII 20100301 |
Clinical relevance of C-reactive protein in ankylosing spondylitis and evaluation of the NSAIDs/coxibs' treatment effect on C-reactive protein. | Rheumatology (Oxford, England) 20100301 |
Preliminary assessment of celecoxib and microdiode pulse laser treatment of diabetic macular edema. | Retina (Philadelphia, Pa.) 20100301 |
In vitro and in vivo evaluation of proniosomes containing celecoxib for oral administration. | AAPS PharmSciTech 20100301 |
Uterine-specific p53 deficiency confers premature uterine senescence and promotes preterm birth in mice. | The Journal of clinical investigation 20100301 |
Markedly reduced toxicity of a hydrogen sulphide-releasing derivative of naproxen (ATB-346). | British journal of pharmacology 20100301 |
Synthesis and biological evaluation of novel pyrazolyl-2,4-thiazolidinediones as anti-inflammatory and neuroprotective agents. | Bioorganic & medicinal chemistry 20100301 |
Cyclooxygenase-2 inhibition does not improve the reduction in ductal carcinoma in situ proliferation with aromatase inhibitor therapy: results of the ERISAC randomized placebo-controlled trial. | Clinical cancer research : an official journal of the American Association for Cancer Research 20100301 |
Chronic cyclooxygenase-2 inhibition promotes myofibroblast-associated intestinal fibrosis. | Cancer prevention research (Philadelphia, Pa.) 20100301 |
Risk factors of drug interaction between warfarin and nonsteroidal anti-inflammatory drugs in practical setting. | Journal of Korean medical science 20100301 |
Effect of celecoxib on proliferation, apoptosis, and survivin expression in human glioma cell line U251. | Chinese journal of cancer 20100301 |
Celecoxib in a 12-year-old boy with familial adenomatous polyposis. | International journal of clinical pharmacology and therapeutics 20100301 |
Antiangiogenic activities of 2,5-dimethyl-celecoxib on the tumor vasculature. | Molecular cancer therapeutics 20100301 |
Hospitalizations for gastrointestinal and cardiovascular events in the CADEUS cohort of traditional or Coxib NSAID users. | British journal of clinical pharmacology 20100301 |
Aspirin-triggered lipoxin in patients treated with aspirin and selective vs. nonselective COX-2 inhibitors. | British journal of clinical pharmacology 20100301 |
[Celecoxib induces cell cycle arrest and apoptosis in human tongue squamous carcinoma cell line Tca8113]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20100301 |
Cyclooxygenase-2 expression in retinoblastoma: an immunohistochemical analysis. | Current eye research 20100301 |
Cyclooxygenase and neuroinflammation in Parkinson's disease neurodegeneration. | Current neuropharmacology 20100301 |
Enhancement of anti-tumor activity by low-dose combination of the recombinant urokinase kringle domain and celecoxib in a glioma model. | Cancer letters 20100227 |
Anti-cancer effects of celecoxib in head and neck carcinoma. | Molecules and cells 20100227 |
Celecoxib inhibits Helicobacter pylori colonization-related factors. | World journal of gastroenterology 20100221 |
Reversal of gene expression changes in the colorectal normal-adenoma pathway by NS398 selective COX2 inhibitor. | British journal of cancer 20100216 |
Synergistic actions of atorvastatin with gamma-tocotrienol and celecoxib against human colon cancer HT29 and HCT116 cells. | International journal of cancer 20100215 |
The effects of nepafenac and amfenac on retinal angiogenesis. | Brain research bulletin 20100215 |
Celecoxib analogs possessing a N-(4-nitrooxybutyl)piperidin-4-yl or N-(4-nitrooxybutyl)-1,2,3,6-tetrahydropyridin-4-yl nitric oxide donor moiety: synthesis, biological evaluation and nitric oxide release studies. | Bioorganic & medicinal chemistry letters 20100215 |
Proteomic analysis in NSAIDs-treated primary cardiomyocytes. | Journal of proteomics 20100210 |
Responder analysis for pain relief and numbers needed to treat in a meta-analysis of etoricoxib osteoarthritis trials: bridging a gap between clinical trials and clinical practice. | Annals of the rheumatic diseases 20100201 |
A COX-2 inhibitor reduces muscle soreness, but does not influence recovery and adaptation after eccentric exercise. | Scandinavian journal of medicine & science in sports 20100201 |
Comparison of mechanical allodynia and the affective component of inflammatory pain in rats. | Neuropharmacology 20100201 |
Cytotoxic effects of celecoxib on Raji lymphoma cells correlate with aggravated endoplasmic reticulum stress but not with inhibition of cyclooxygenase-2. | Leukemia research 20100201 |
Effect of a cyclooxygenase-2 inhibitor on postexercise muscle protein synthesis in humans. | American journal of physiology. Endocrinology and metabolism 20100201 |
COX-2 expression in chondrosarcoma: a role for celecoxib treatment? | European journal of cancer (Oxford, England : 1990) 20100201 |
Recruited bone marrow cells expressing the EP3 prostaglandin E receptor subtype enhance angiogenesis during chronic inflammation. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100201 |
Cytokine profiles induced by the novel swine-origin influenza A/H1N1 virus: implications for treatment strategies. | The Journal of infectious diseases 20100201 |
Host prostaglandin EP3 receptor signaling relevant to tumor-associated lymphangiogenesis. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20100201 |
Suppressive effect of COX2 inhibitor on the progression of adipose inflammation in high-fat-induced obese rats. | European journal of clinical investigation 20100201 |
Influence of LOX/COX inhibitors on cell differentiation induced by all-trans retinoic acid in neuroblastoma cell lines. | International journal of molecular medicine 20100201 |
Pharmacophore modeling and virtual screening for designing potential 5-lipoxygenase inhibitors. | Bioorganic & medicinal chemistry letters 20100201 |
Absorption and distribution of etoricoxib in plasma, CSF, and wound tissue in patients following hip surgery--a pilot study. | Naunyn-Schmiedeberg's archives of pharmacology 20100201 |
Design, synthesis and biological evaluation of new 2,3-diarylquinoline derivatives as selective cyclooxygenase-2 inhibitors. | Bioorganic & medicinal chemistry 20100201 |
Severe adverse skin reactions to nonsteroidal antiinflammatory drugs: A review of the literature. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20100201 |
Biological activity of celecoxib in the bronchial epithelium of current and former smokers. | Cancer prevention research (Philadelphia, Pa.) 20100201 |
Cyclooxygenase-2 inhibition for the prophylaxis and treatment of preinvasive breast cancer in a her-2/neu mouse model. | Cancer prevention research (Philadelphia, Pa.) 20100201 |
Assessing efficacy in early-phase cancer prevention clinical trials: the case of ki-67 in the lung. | Cancer prevention research (Philadelphia, Pa.) 20100201 |
Celecoxib-induced apoptosis is enhanced by ABT-737 and by inhibition of autophagy in human colorectal cancer cells. | Autophagy 20100201 |
Nonsteroidal antiinflammatory drugs and prostaglandin E(2) modulate the synthesis of osteoprotegerin and RANKL in the cartilage of patients with severe knee osteoarthritis. | Arthritis and rheumatism 20100201 |
[Selective inhibitors of cyclooxygenase-2 (COX-2), celecoxib and parecoxib: a systematic review]. | Drugs of today (Barcelona, Spain : 1998) 20100201 |
Biomarkers of inflammation in cattle determining the effectiveness of anti-inflammatory drugs. | Journal of veterinary pharmacology and therapeutics 20100201 |
Naproxen aggravates doxorubicin-induced cardiomyopathy in rats. | Indian journal of pharmacology 20100201 |
Prostaglandin E2 upregulates survivin expression via the EP1 receptor in hepatocellular carcinoma cells. | Life sciences 20100130 |
Novel ester and acid derivatives of the 1,5-diarylpyrrole scaffold as anti-inflammatory and analgesic agents. Synthesis and in vitro and in vivo biological evaluation. | Journal of medicinal chemistry 20100128 |
Toward safer processes for C-C biaryl bond construction: catalytic direct C-H arylation and tin-free radical coupling in the synthesis of pyrazolophenanthridines. | The Journal of organic chemistry 20100115 |
Discovery of 3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide as a novel dual cyclooxygenase/5-lipoxygenase inhibitor that also inhibits tumor necrosis factor-alpha production. | Bioorganic & medicinal chemistry 20100115 |
Cardiotoxicity of anticancer drugs: the need for cardio-oncology and cardio-oncological prevention. | Journal of the National Cancer Institute 20100106 |
[11C]-PK11195 PET: quantification of neuroinflammation and a monitor of anti-inflammatory treatment in Parkinson's disease? | Parkinsonism & related disorders 20100101 |
Celecoxib prevents tumor growth in an animal model by a COX-2 independent mechanism. | Cancer chemotherapy and pharmacology 20100101 |
Nanoemulsion: a promising tool for solubility and dissolution enhancement of celecoxib. | Pharmaceutical development and technology 20100101 |
Celecoxib reduces the effects of acute and chronic UVB exposure in mice treated with therapeutically relevant immunosuppressive drugs. | International journal of cancer 20100101 |
Differential effects of anti-apoptotic Bcl-2 family members Mcl-1, Bcl-2, and Bcl-xL on celecoxib-induced apoptosis. | Biochemical pharmacology 20100101 |
Short-term celecoxib to regress long-term persistent gastric intestinal metaplasia after Helicobacter pylori eradication. | Journal of gastroenterology and hepatology 20100101 |
Phase II nonrandomized study of the efficacy and safety of COX-2 inhibitor celecoxib on patients with cancer cachexia. | Journal of molecular medicine (Berlin, Germany) 20100101 |
A novel composite endpoint to evaluate the gastrointestinal (GI) effects of nonsteroidal antiinflammatory drugs through the entire GI tract. | The Journal of rheumatology 20100101 |
KO-202125, a sauristolactam derivate, induces apoptosis to prevent KB human oral squamous carcinoma cells through inhibition of cyclooxygenase-2 expression. | European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20100101 |
Criterion for excipients screening in the development of nanoemulsion formulation of three anti-inflammatory drugs. | Pharmaceutical development and technology 20100101 |
The murine cerebral malaria phenomenon. | Trends in parasitology 20100101 |
Mechanisms of Kv2.1 channel inhibition by celecoxib--modification of gating and channel block. | British journal of pharmacology 20100101 |
Basal cell carcinoma chemoprevention with nonsteroidal anti-inflammatory drugs in genetically predisposed PTCH1+/- humans and mice. | Cancer prevention research (Philadelphia, Pa.) 20100101 |
Overexpression of cyclooxygenase-2 in rat oral cancers and prevention of oral carcinogenesis in rats by selective and nonselective COX inhibitors. | Cancer prevention research (Philadelphia, Pa.) 20100101 |
Atorvastatin and celecoxib in combination inhibits the progression of androgen-dependent LNCaP xenograft prostate tumors to androgen independence. | Cancer prevention research (Philadelphia, Pa.) 20100101 |
Effectiveness of diclofenac versus acetaminophen in primary care patients with knee osteoarthritis: [NTR1485], DIPA-trial: design of a randomized clinical trial. | BMC musculoskeletal disorders 20100101 |
Water displacement leg volumetry in clinical studies--a discussion of error sources. | BMC medical research methodology 20100101 |
Antivascular therapy for epithelial ovarian cancer. | Journal of oncology 20100101 |
Celecoxib inhibits CD133-positive cell migration via reduction of CCR2 in Helicobacter pylori-infected Mongolian gerbils. | Digestion 20100101 |
Progressive changes in microglia and macrophages in spinal cord and peripheral nerve in the transgenic rat model of amyotrophic lateral sclerosis. | Journal of neuroinflammation 20100101 |
Synergistic effect of gefitinib and rofecoxib in mesothelioma cells. | Molecular cancer 20100101 |
Chronic infection during placental malaria is associated with up-regulation of cycloxygenase-2. | Malaria journal 20100101 |
Reduced levels of hydroxylated, polyunsaturated ultra long-chain fatty acids in the serum of colorectal cancer patients: implications for early screening and detection. | BMC medicine 20100101 |
In-vivo transfection of pcDNA3.1-IGFBP7 inhibits melanoma growth in mice through apoptosis induction and VEGF downexpression. | Journal of experimental & clinical cancer research : CR 20100101 |
Progress in COX-2 inhibitors: a journey so far. | Current medicinal chemistry 20100101 |
Acute NMDA toxicity in cultured rat cerebellar granule neurons is accompanied by autophagy induction and late onset autophagic cell death phenotype. | BMC neuroscience 20100101 |
Prevalence of genetic polymorphisms in the promoter region of the alpha-1 antitrypsin (SERPINA1) gene in chronic liver disease: a case control study. | BMC gastroenterology 20100101 |
Elevated ratio of urinary metabolites of thromboxane and prostacyclin is associated with adverse cardiovascular events in ADAPT. | PloS one 20100101 |
Effects of Liver x receptor agonist treatment on signal transduction pathways in acute lung inflammation. | Respiratory research 20100101 |
Insight in modulation of inflammation in response to diclofenac intervention: a human intervention study. | BMC medical genomics 20100101 |
Cyclooxygenase-2 enhances alpha2beta1 integrin expression and cell migration via EP1 dependent signaling pathway in human chondrosarcoma cells. | Molecular cancer 20100101 |
[Reducing effect of curcumin on expressions of TNF-alpha, IL-6 and IL-8 in rats with chronic nonbacterial prostatitis]. | Zhonghua nan ke xue = National journal of andrology 20100101 |
Nonsteroidal Anti-Inflammatory Drugs: A survey of practices and concerns of pediatric medical and surgical specialists and a summary of available safety data. | Pediatric rheumatology online journal 20100101 |
Low direct cytotoxicity of loxoprofen on gastric mucosal cells. | Biological & pharmaceutical bulletin 20100101 |
Prescriptions for selective cyclooxygenase-2 inhibitors, non-selective non-steroidal anti-inflammatory drugs, and risk of breast cancer in a population-based case-control study. | Breast cancer research : BCR 20100101 |
Cost effectiveness of etoricoxib versus celecoxib and non-selective NSAIDS in the treatment of ankylosing spondylitis. | PharmacoEconomics 20100101 |
Multimodal therapy for synergic inhibition of tumour cell invasion and tumour-induced angiogenesis. | BMC cancer 20100101 |
Downregulation of Epidermal Growth Factor Receptor Expression Contributes to alpha-TEA's Proapoptotic Effects in Human Ovarian Cancer Cell Lines. | Journal of oncology 20100101 |
A phase II study of high-dose celecoxib and metronomic 'low-dose' cyclophosphamide and methotrexate in patients with relapsed and refractory lymphoma. | Hematology/oncology and stem cell therapy 20100101 |
Reduced uptake of the proliferation-seeking radiotracer technetium-99m-labelled pentavalent dimercaptosuccinic acid in a 47-year-old woman with severe breast epithelial hyperplasia taking ibuprofen: a case report. | Journal of medical case reports 20100101 |
The cytoprotective drug amifostine modifies both expression and activity of the pro-angiogenic factor VEGF-A. | BMC medicine 20100101 |
The role of cyclooxygenase-2 in cell proliferation and cell death in human malignancies. | International journal of cell biology 20100101 |
Expression and prognostic significance of Cox-2 and p-53 in Hodgkin lymphomas: a retrospective study. | Diagnostic pathology 20100101 |
Tamoxifen enhances the Hsp90 molecular chaperone ATPase activity. | PloS one 20100101 |
Reporting bias in medical research - a narrative review. | Trials 20100101 |
Cyclooxygenase-2 expression in oligodendrocytes increases sensitivity to excitotoxic death. | Journal of neuroinflammation 20100101 |
Effect of celecoxib, a selective cyclooxygenase-2 inhibitor on carbon tetrachloride intoxication in rats. | Biological & pharmaceutical bulletin 20100101 |
Antiangiogenic therapy and mechanisms of tumor resistance in malignant glioma. | Journal of oncology 20100101 |
Effects of selective and non-selective cyclooxygenase (COX) inhibitors on postoperative adhesion formation in a rat uterine horn model. | Clinical and experimental obstetrics & gynecology 20100101 |
Tumor tissue-derived formaldehyde and acidic microenvironment synergistically induce bone cancer pain. | PloS one 20100101 |
BCAN Think Tank session 3: Prevention of bladder cancer. | Urologic oncology 20100101 |
[The assessment of oral NSAID use in patients with rheumatoid arthritis in Hungary--a cross sectional non interventional study]. | Acta pharmaceutica Hungarica 20100101 |
Architectural heterogeneity in tumors caused by differentiation alters intratumoral drug distribution and affects therapeutic synergy of antiangiogenic organoselenium compound. | Journal of oncology 20100101 |
Enhancement of ATRA-induced differentiation of neuroblastoma cells with LOX/COX inhibitors: an expression profiling study. | Journal of experimental & clinical cancer research : CR 20100101 |
The effects of COX-2 anti-inflammatory drugs on soft tissue healing: a review of the literature. | Journal of biological regulators and homeostatic agents 20100101 |
Etoricoxib--preemptive and postoperative analgesia (EPPA) in patients with laparotomy or thoracotomy--design and protocols. | Trials 20100101 |
COX-2 as a target for cancer chemotherapy. | Pharmacological reports : PR 20100101 |
Optical tomographic imaging discriminates between disease-modifying anti-rheumatic drug (DMARD) and non-DMARD efficacy in collagen antibody-induced arthritis. | Arthritis research & therapy 20100101 |
Role and rationale for the use of milnacipran in the management of fibromyalgia. | Neuropsychiatric disease and treatment 20100101 |
Design of group IIA secreted/synovial phospholipase A(2) inhibitors: an oxadiazolone derivative suppresses chondrocyte prostaglandin E(2) secretion. | PloS one 20100101 |
Use of nonsteroidal anti-inflammatory drugs in patients with cardiovascular disease: a cautionary tale. | Cardiology in review 20100101 |
Targeting the tumor microenvironment using photodynamic therapy combined with inhibitors of cyclooxygenase-2 or vascular endothelial growth factor. | Methods in molecular biology (Clifton, N.J.) 20100101 |
Presenilin/gamma-Secretase and Inflammation. | Frontiers in aging neuroscience 20100101 |
Curcumin mediated suppression of nuclear factor-κB promotes chondrogenic differentiation of mesenchymal stem cells in a high-density co-culture microenvironment. | Arthritis research & therapy 20100101 |
A female with rash and facial swelling. | Journal of emergencies, trauma, and shock 20100101 |
Single dose oral lumiracoxib for postoperative pain in adults. | The Cochrane database of systematic reviews 20100101 |
Influence of cyclodextrin complexation with NSAIDs on NSAID/cold stress-induced gastric ulceration in rats. | International journal of medical sciences 20100101 |
Therapeutic cancer vaccines in combination with conventional therapy. | Journal of biomedicine & biotechnology 20100101 |
RNAi-based strategies for cyclooxygenase-2 inhibition in cancer. | Journal of biomedicine & biotechnology 20100101 |
Establishing a distributed system for the simple representation and integration of diverse scientific assertions. | Journal of biomedical semantics 20100101 |
Decreased risk of squamous cell carcinoma of the head and neck in users of nonsteroidal anti-inflammatory drugs. | International journal of otolaryngology 20100101 |
Comparison of glucose derivatives effects on cartilage degradation. | BMC musculoskeletal disorders 20100101 |
Vane's blood-bathed organ technique adapted to examine the endothelial effects of cardiovascular drugs in vivo. | Pharmacological reports : PR 20100101 |
The Analgesic Activity of Bestatin as a Potent APN Inhibitor. | Frontiers in neuroscience 20100101 |
The role of prostaglandin E2 (PGE 2) in toll-like receptor 4 (TLR4)-mediated colitis-associated neoplasia. | BMC gastroenterology 20100101 |
Current implications of cyclophilins in human cancers. | Journal of experimental & clinical cancer research : CR 20100101 |
Caffeine: a potential complexing agent for solubility and dissolution enhancement of celecoxib. | Pharmaceutical biology 20100101 |
Rhizoma Coptidis inhibits LPS-induced MCP-1/CCL2 production in murine macrophages via an AP-1 and NFkappaB-dependent pathway. | Mediators of inflammation 20100101 |
Price regulation, new entry, and information shock on pharmaceutical market in Taiwan: a nationwide data-based study from 2001 to 2004. | BMC health services research 20100101 |
Pharmacologic inhibition of COX-1 and COX-2 in influenza A viral infection in mice. | PloS one 20100101 |
Association of sulfotransferase SULT1A1 with breast cancer risk: a meta-analysis of case-control studies with subgroups of ethnic and menopausal statue. | Journal of experimental & clinical cancer research : CR 20100101 |
Subchondral bone microstructural damage by increased remodelling aggravates experimental osteoarthritis preceded by osteoporosis. | Arthritis research & therapy 20100101 |
Role of COX-2 in cough reflex sensitivity to inhaled capsaicin in patients with sinobronchial syndrome. | Cough (London, England) 20100101 |
Targeting DNA damage and repair by curcumin. | Breast cancer : basic and clinical research 20100101 |
Parthenolide induces proliferation inhibition and apoptosis of pancreatic cancer cells in vitro. | Journal of experimental & clinical cancer research : CR 20100101 |
Are NSAIDs useful to treat Alzheimer's disease or mild cognitive impairment? | Frontiers in aging neuroscience 20100101 |
A multiparameter approach to monitor disease activity in collagen-induced arthritis. | Arthritis research & therapy 20100101 |
Gefitinib radiosensitizes non-small cell lung cancer cells through inhibition of ataxia telangiectasia mutated. | Molecular cancer 20100101 |
Tumour suppressor function of MDA-7/IL-24 in human breast cancer. | Cancer cell international 20100101 |
Rationale of using different biological therapies in rheumatoid arthritis. | Arthritis research & therapy 20100101 |
Neuroinflammation, microglia and implications for anti-inflammatory treatment in Alzheimer's disease. | International journal of Alzheimer's disease 20100101 |
Animal models of ischemic stroke. Part one: modeling risk factors. | The open neurology journal 20100101 |
COX-2 inhibition improves immunotherapy and is associated with decreased numbers of myeloid-derived suppressor cells in mesothelioma. Celecoxib influences MDSC function. | BMC cancer 20100101 |
Small-bowel capsule endoscopy in patients with suspected Crohn's disease-diagnostic value and complications. | Diagnostic and therapeutic endoscopy 20100101 |
Primary stabbing headache. | Handbook of clinical neurology 20100101 |
Saccharomyces cerevisiae β-carbonic anhydrase: inhibition and activation studies. | Current pharmaceutical design 20100101 |
Coordinated increased expression of Cyclooxygenase2 and nuclear factor κB is a steady feature of urinary bladder carcinogenesis. | Advances in urology 20100101 |
The ketogenic diet reverses gene expression patterns and reduces reactive oxygen species levels when used as an adjuvant therapy for glioma. | Nutrition & metabolism 20100101 |
Regulation of heparin-binding EGF-like growth factor by miR-212 and acquired cetuximab-resistance in head and neck squamous cell carcinoma. | PloS one 20100101 |
Inhibitory effect of selective cyclooxygenase-2 inhibitor lumiracoxib on human organic anion transporters hOAT1 and hOAT3. | Drug metabolism and pharmacokinetics 20100101 |
The use of in vitro technologies coupled with high resolution accurate mass LC-MS for studying drug metabolism in equine drug surveillance. | Drug testing and analysis 20100101 |
Evaluation of the effect of intrathecal clonidine to decrease shoulder tip pain in laparoscopy under spinal anaesthesia. | Indian journal of anaesthesia 20100101 |
Curcumin protects intestinal mucosal barrier function of rat enteritis via activation of MKP-1 and attenuation of p38 and NF-κB activation. | PloS one 20100101 |
Curcumin, the golden spice from Indian saffron, is a chemosensitizer and radiosensitizer for tumors and chemoprotector and radioprotector for normal organs. | Nutrition and cancer 20100101 |
Celecoxib inhibits β-catenin-dependent survival of the human osteosarcoma MG-63 cell line. | The Journal of international medical research 20100101 |
Efficacy of a multimodal analgesia protocol in total knee arthroplasty: a randomized, controlled trial. | The Journal of international medical research 20100101 |
Combined inhibitory effects of celecoxib and fluvastatin on the growth of human hepatocellular carcinoma xenografts in nude mice. | The Journal of international medical research 20100101 |
Effects of Garlic on Cytochromes P450 2C9- and 3A4-Mediated Drug Metabolism in Human Hepatocytes. | Scientia pharmaceutica 20100101 |
Materials for pharmaceutical dosage forms: molecular pharmaceutics and controlled release drug delivery aspects. | International journal of molecular sciences 20100101 |
Abalone visceral extract inhibit tumor growth and metastasis by modulating Cox-2 levels and CD8+ T cell activity. | BMC complementary and alternative medicine 20100101 |
Comparing etoricoxib and celecoxib for preemptive analgesia for acute postoperative pain in patients undergoing arthroscopic anterior cruciate ligament reconstruction: a randomized controlled trial. | BMC musculoskeletal disorders 20100101 |
α-TEA-induced death receptor dependent apoptosis involves activation of acid sphingomyelinase and elevated ceramide-enriched cell surface membranes. | Cancer cell international 20100101 |
Alkylation of the tumor suppressor PTEN activates Akt and β-catenin signaling: a mechanism linking inflammation and oxidative stress with cancer. | PloS one 20100101 |
Feasibility of incorporating genomic knowledge into electronic medical records for pharmacogenomic clinical decision support. | BMC bioinformatics 20100101 |
Old and new insights in the treatment of thyroid carcinoma. | Journal of thyroid research 20100101 |
Effects of alpha-calcitonin gene-related peptide on osteoprotegerin and receptor activator of nuclear factor-κB ligand expression in MG-63 osteoblast-like cells exposed to polyethylene particles. | Journal of orthopaedic surgery and research 20100101 |
Effects of capecitabine and celecoxib in experimental pancreatic cancer. | Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20100101 |
Synergistic effect of celecoxib on 5-fluorouracil-induced apoptosis in hepatocellular carcinoma patients. | Annals of hepatology 20100101 |
Comparative efficacy and tolerability of 5-Loxin and AflapinAgainst osteoarthritis of the knee: a double blind, randomized, placebo controlled clinical study. | International journal of medical sciences 20100101 |
25-Hydroxycholesterol exerts both a cox-2-dependent transient proliferative effect and cox-2-independent cytotoxic effect on bovine endothelial cells in a time- and cell-type-dependent manner. | Journal of angiogenesis research 20100101 |
Curcumin activates the p38MPAK-HSP25 pathway in vitro but fails to attenuate diabetic nephropathy in DBA2J mice despite urinary clearance documented by HPLC. | BMC complementary and alternative medicine 20100101 |
COX-2 activation is associated with Akt phosphorylation and poor survival in ER-negative, HER2-positive breast cancer. | BMC cancer 20100101 |
Could chiropractors screen for adverse drug events in the community? Survey of US chiropractors. | Chiropractic & osteopathy 20100101 |
Combining nitric oxide release with anti-inflammatory activity preserves nigrostriatal dopaminergic innervation and prevents motor impairment in a 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine model of Parkinson's disease. | Journal of neuroinflammation 20100101 |
Defining a minimal clinically important difference for endometriosis-associated pelvic pain measured on a visual analog scale: analyses of two placebo-controlled, randomized trials. | Health and quality of life outcomes 20100101 |
Maintenance therapy of celecoxib for major depression with mimicking neuropsychological dysfunction. | General hospital psychiatry 20100101 |
Topical piroxicam in vitro release and in vivo anti-inflammatory and analgesic effects from palm oil esters-based nanocream. | International journal of nanomedicine 20100101 |
[Prevention of NSAID gastropathy: the difference between a coxibs and the addition of a PPI]. | Nederlands tijdschrift voor geneeskunde 20100101 |
The effect of phosphorylated Akt inhibition on posterior capsule opacification in an ex vivo canine model. | Molecular vision 20100101 |
Deciphering the pathogenesis of tendinopathy: a three-stages process. | Sports medicine, arthroscopy, rehabilitation, therapy & technology : SMARTT 20100101 |
Changes in Physical Activity Involvement and Attitude to Physical Activity in a 16-Year Follow-Up Study among the Elderly. | Journal of aging research 20100101 |
Existing data sources for clinical epidemiology: Aarhus University Prescription Database. | Clinical epidemiology 20100101 |
Cyclin D1 expression and the inhibitory effect of celecoxib on ovarian tumor growth in vivo. | International journal of molecular sciences 20100101 |
Efficacy of intra-articular injection of celecoxib in a rabbit model of osteoarthritis. | International journal of molecular sciences 20100101 |
Staging anti-inflammatory therapy in Alzheimer's disease. | Frontiers in aging neuroscience 20100101 |
Efficacy and safety of Ayurvedic medicines: Recommending equivalence trial design and proposing safety index. | International journal of Ayurveda research 20100101 |
DNA aptamers as molecular probes for colorectal cancer study. | PloS one 20100101 |
Pharmacophore elucidation and molecular docking studies on 5-phenyl-1-(3-pyridyl)-1h-1,2,4-triazole-3-carboxylic acid derivatives as COX-2 inhibitors. | Scientia pharmaceutica 20100101 |
Preparation and in vivo evaluation of indomethacin loaded true nanoemulsions. | Scientia pharmaceutica 20100101 |
Optimal management of cancer anorexia-cachexia syndrome. | Cancer management and research 20100101 |
Suppression of tumorigenesis: modulation of inflammatory cytokines by oral administration of microencapsulated probiotic yogurt formulation. | International journal of inflammation 20100101 |
Anticonvulsant effect of celecoxib on pentylenetetrazole-induced convulsion: Modulation by NO pathway. | Acta neurobiologiae experimentalis 20100101 |
Intravenous ibuprofen: the first injectable product for the treatment of pain and fever. | Journal of pain research 20100101 |
Pilot study: rapidly cycling hypobaric pressure improves pain after 5 days in adiposis dolorosa. | Journal of pain research 20100101 |
Investigational pharmacology for low back pain. | Journal of pain research 20100101 |
Topical nonsteroidal anti-inflammatory drugs for the treatment of pain due to soft tissue injury: diclofenac epolamine topical patch. | Journal of pain research 20100101 |
Natural anti-inflammatory agents for pain relief. | Surgical neurology international 20100101 |
Treatment of cachexia in oncology. | Indian journal of palliative care 20100101 |
Formulation and evaluation of extended-release solid dispersion of metformin hydrochloride. | Journal of young pharmacists : JYP 20100101 |
COX-2 Inhibition by Use of Rofecoxib or High Dose Aspirin Enhances ADP-Induced Platelet Aggregation in Fresh Blood. | The open cardiovascular medicine journal 20100101 |
Cytotoxicity of apigenin on leukemia cell lines: implications for prevention and therapy. | Cell death & disease 20100101 |
Preventive but not curative efficacy of celecoxib on bladder carcinogenesis in a rat model. | Mediators of inflammation 20100101 |
Cyclooxygenase-2 inhibition restored endothelium-mediated relaxation in old obese zucker rat mesenteric arteries. | Frontiers in physiology 20100101 |
Vitamin B12 Deficiency due to Chlorofluorocarbon: A Case Report. | Case reports in medicine 20100101 |
Mechanism of dissolution enhancement and bioavailability of poorly water soluble celecoxib by preparing stable amorphous nanoparticles. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20100101 |
Docosahexaenoic acid reduces amyloid-β(1-42) secretion in human AβPP-transfected CHO-cells by mechanisms other than inflammation related to PGE₂. | Journal of Alzheimer's disease : JAD 20100101 |
Revisiting the association between candidal infection and carcinoma, particularly oral squamous cell carcinoma. | Journal of oral microbiology 20100101 |
Ayurveda-modern medicine interface: A critical appraisal of studies of Ayurvedic medicines to treat osteoarthritis and rheumatoid arthritis. | Journal of Ayurveda and integrative medicine 20100101 |
Colon delivery of budesonide using solid dispersion in dextran for the treatment and secondary prevention of ulcerative colitis in rat. | International journal of preventive medicine 20100101 |
New and improved strategies for the treatment of gout. | International journal of nephrology and renovascular disease 20100101 |
The Murine Angiotensin II-Induced Abdominal Aortic Aneurysm Model: Rupture Risk and Inflammatory Progression Patterns. | Frontiers in pharmacology 20100101 |
Risk of Upper Gastrointestinal Bleeding in a Cohort of New Users of Low-Dose ASA for Secondary Prevention of Cardiovascular Outcomes. | Frontiers in pharmacology 20100101 |
Cognitive psychiatry in India. | Indian journal of psychiatry 20100101 |
Microsomal prostaglandin e synthase-1 in rheumatic diseases. | Frontiers in pharmacology 20100101 |
Curcumin-the paradigm of a multi-target natural compound with applications in cancer prevention and treatment. | Toxins 20100101 |
Recent trends in the impurity profile of pharmaceuticals. | Journal of advanced pharmaceutical technology & research 20100101 |
Might salicylate exert benefits against childhood cancer? | Ecancermedicalscience 20100101 |
Lidocaine 5% patch for localized neuropathic pain: progress for the patient, a new approach for the physician. | Clinical pharmacology : advances and applications 20100101 |
The effect of full length and mature NAG-1 protein overexpression on cytotoxicity of celecoxib, tamoxifen and doxorubicin in HT1080. | Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences 20100101 |
A protocol for labrador retrievers? | Lancet (London, England) 20091219 |
Matrix metalloproteinase (MMP)-1 and MMP-3 induce macrophage MMP-9: evidence for the role of TNF-alpha and cyclooxygenase-2. | Journal of immunology (Baltimore, Md. : 1950) 20091215 |
NSAID prescribing precautions. | American family physician 20091215 |
Novel nitro-oxy derivatives of celecoxib for the regulation of colon cancer cell growth. | Chemico-biological interactions 20091210 |
[Rheumatoid arthritis and depression]. | MMW Fortschritte der Medizin 20091210 |
Synthesis, biological evaluation, and molecular modeling of oleuropein and its semisynthetic derivatives as cyclooxygenase inhibitors. | Journal of agricultural and food chemistry 20091209 |
Spectroscopic study on the interaction of celecoxib with human carbonic anhydrase II: thermodynamic characterization of the binding process. | Journal of photochemistry and photobiology. B, Biology 20091202 |
Protective effect of cyclooxygenase (COX)-inhibitors against drug-induced catatonia and MPTP-induced striatal lesions in rats. | Pharmacology, biochemistry, and behavior 20091201 |
Celecoxib treatment reduces peritoneal fibrosis and angiogenesis and prevents ultrafiltration failure in experimental peritoneal dialysis. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20091201 |
Cyclooxygenase-2 plays a critical role in retinal ganglion cell death after transient ischemia: real-time monitoring of RGC survival using Thy-1-EGFP transgenic mice. | Neuroscience research 20091201 |
Cyclooxygenase-2 inhibitor: a potential therapeutic strategy for ultrafiltration failure in peritoneal dialysis. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20091201 |
Complement C5a stimulates food intake via a prostaglandin D(2)- and neuropeptide Y-dependent mechanism in mice. | Prostaglandins & other lipid mediators 20091201 |
PC-407, a celecoxib derivative, inhibited the growth of colorectal tumor in vitro and in vivo. | Cancer science 20091201 |
NSAID switching and short-term gastrointestinal outcome rates after the withdrawal of rofecoxib. | Pharmacoepidemiology and drug safety 20091201 |
Carbonic anhydrase inhibitors. Characterization and inhibition studies of the most active beta-carbonic anhydrase from Mycobacterium tuberculosis, Rv3588c. | Bioorganic & medicinal chemistry letters 20091201 |
Discovery of benzo[g]indol-3-carboxylates as potent inhibitors of microsomal prostaglandin E(2) synthase-1. | Bioorganic & medicinal chemistry 20091201 |
Do COX-2 inhibitors raise blood pressure more than nonselective NSAIDs and placebo? An updated meta-analysis. | Journal of hypertension 20091201 |
High celecoxib-loaded nanoparticles prepared by a vibrating nozzle device. | Journal of microencapsulation 20091201 |
Update on the management of pain in arthritis and the use of cyclooxygenase-2 inhibitors. | Current pain and headache reports 20091201 |
Pregabalin, celecoxib, and their combination for treatment of chronic low-back pain. | Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology 20091201 |
COX-2 inhibitors are contraindicated for treatment of combined injury. | Radiation research 20091201 |
Risk of upper gastrointestinal complications associated with cyclooxygenase-2 selective and nonselective nonsteroidal antiinflammatory drugs. | Pharmacotherapy 20091201 |
The effect of cyclooxygenase-2 expression on tumor volume response in patients treated with radiotherapy for uterine cervical cancer. | Journal of Korean medical science 20091201 |
A comparison of cost effectiveness using data from randomized trials or actual clinical practice: selective cox-2 inhibitors as an example. | PLoS medicine 20091201 |
Inhibitory Effect of IFN-beta, on the Antitumor Activity of Celecoxib in U87 Glioma Model. | Journal of Korean Neurosurgical Society 20091201 |
Gastrointestinal and cardiovascular risk of non-selective NSAIDs and COX-2 inhibitors in elderly patients with knee osteoarthritis. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20091201 |
New insights into the structural features and functional relevance of human cytochrome P450 2C9. Part I. | Current drug metabolism 20091201 |
Potential of ezetimibe in memory deficits associated with dementia of Alzheimer's type in mice. | Indian journal of pharmacology 20091201 |
[Celecoxib increased cellular ATRA sensitivity of human colon cancer cell lines through COX-2-independent mechanisms]. | Yao xue xue bao = Acta pharmaceutica Sinica 20091201 |
Promising therapy for Alzheimer's disease targeting angiotensinconverting enzyme and the cyclooxygense-2 isoform. | Drug discoveries & therapeutics 20091201 |
COX-2 inhibitors in patients with sensitivity to nonselective NSAIDs. | The New England journal of medicine 20091126 |
Protective activity of Theobroma cacao L. phenolic extract on AML12 and MLP29 liver cells by preventing apoptosis and inducing autophagy. | Journal of agricultural and food chemistry 20091125 |
Clinical trial: the impact of cyclooxygenase inhibitors on gastrointestinal recovery after major surgery - a randomized double blind controlled trial of celecoxib or diclofenac vs. placebo. | Alimentary pharmacology & therapeutics 20091115 |
Silibinin prevents TPA-induced MMP-9 expression by down-regulation of COX-2 in human breast cancer cells. | Journal of ethnopharmacology 20091112 |
Celecoxib induces hepatic stellate cell apoptosis through inhibition of Akt activation and suppresses hepatic fibrosis in rats. | Gut 20091101 |
Inhibition of 12-LOX and COX-2 reduces the proliferation of human epidermoid carcinoma cells (A431) by modulating the ERK and PI3K-Akt signalling pathways. | Experimental dermatology 20091101 |
Comparison of microsomal prostaglandin E synthase-1 deletion and COX-2 inhibition in acute cardiac ischemia in mice. | Prostaglandins & other lipid mediators 20091101 |
Celecoxib in the management of acute renal colic: a randomized controlled clinical trial. | Urology 20091101 |
Differential effects of selective cyclooxygenase-2 inhibitors on vascular smooth muscle ion channels may account for differences in cardiovascular risk profiles. | Molecular pharmacology 20091101 |
Non-aspirin NSAIDs, cyclooxygenase-2 inhibitors and risk for cardiovascular events-stroke, acute myocardial infarction, and death from coronary heart disease. | Pharmacoepidemiology and drug safety 20091101 |
Inhibition of prostaglandin E(2) signaling through the EP(1) receptor does not affect prostacyclin production in human endothelial cells. | Prostaglandins & other lipid mediators 20091101 |
An ion channel hypothesis to explain divergent cardiovascular safety of cyclooxygenase-2 inhibitors: the answer to a hotly debated puzzle? | Molecular pharmacology 20091101 |
Nature meets nurture: molecular genetics of gastric cancer. | Human genetics 20091101 |
Prolonged low-dose administration of the cyclooxygenase-2 inhibitor celecoxib enhances the antitumor activity of irinotecan against neuroblastoma xenografts. | Cancer science 20091101 |
Synthesis of carbon-11 labeled celecoxib derivatives as new candidate PET radioligands for imaging of inflammation. | Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 20091101 |
APC10.1 cells as a model for assessing the efficacy of potential chemopreventive agents in the Apc(Min) mouse model in vivo. | European journal of cancer (Oxford, England : 1990) 20091101 |
The use of selective cyclooxygenase-2 inhibitors and the risk of acute myocardial infarction in Saskatchewan, Canada. | Pharmacoepidemiology and drug safety 20091101 |
Double blind randomized phase II study with radiation+5-fluorouracil+/-celecoxib for resectable rectal cancer. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20091101 |
Chemoprevention of colonic polyps with balsalazide: an exploratory, double-blind, placebo-controlled study. | Digestive diseases and sciences 20091101 |
Genome wide analysis and comparative docking studies of new diaryl furan derivatives against human cyclooxygenase-2, lipoxygenase, thromboxane synthase and prostacyclin synthase enzymes involved in inflammatory pathway. | Journal of molecular graphics & modelling 20091101 |
Synergistic effects of lovastatin and celecoxib on caveolin-1 and its down-stream signaling molecules: Implications for colon cancer prevention. | International journal of oncology 20091101 |
Effect of celecoxib on emotional stress and pain-related behaviors evoked by experimental tooth movement in the rat. | The Angle orthodontist 20091101 |
Pharmacological inhibition of 5-lipoxygenase accelerates and enhances fracture-healing. | The Journal of bone and joint surgery. American volume 20091101 |
Effects of No.2 Renal Failure Recipe on expressions of cyclooxygenase-2 and -1 mRNAs in rats with chronic renal failure. | Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20091101 |
[Inhibitory effects of COX-2 inhibitor on migration of human tongue squamous cell carcinoma Tca8113 cells]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20091101 |
[Celecoxib inhibits gastric adenocarcinoma growth via inducing expression of human nonsteroidal anti-inflammatory drug activated gene]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20091101 |
Changes in physicians' practice of prescribing cyclooxygenase-2 inhibitor after market withdrawal of rofecoxib: a retrospective study of physician-patient pairs in Taiwan. | Clinical therapeutics 20091101 |
Metabolomics in drug intolerance. | Current drug metabolism 20091101 |
The effect of dietary and topical celecoxib on 4-nitroquinoline-1-oxide-induced lingual epithelium alternations in rat. | JPMA. The Journal of the Pakistan Medical Association 20091101 |
Short-term celecoxib intervention is a safe and effective chemopreventive for gastric carcinogenesis based on a Mongolian gerbil model. | World journal of gastroenterology 20091021 |
Tom MacDonald replies to Marisa de Andrade. | BMJ (Clinical research ed.) 20091021 |
Informative clinical investigation: a demanding taskmaster. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091020 |
Phase II, randomized, placebo-controlled trial of neoadjuvant celecoxib in men with clinically localized prostate cancer: evaluation of drug-specific biomarkers. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20091020 |
NFAT signalling is a novel target of oncogenic BRAF in metastatic melanoma. | British journal of cancer 20091020 |
Inhibition of azoxymethane-induced colorectal cancer by CP-31398, a TP53 modulator, alone or in combination with low doses of celecoxib in male F344 rats. | Cancer research 20091015 |
Pyridine analogues of nimesulide: design, synthesis, and in vitro and in vivo pharmacological evaluation as promising cyclooxygenase 1 and 2 inhibitors. | Journal of medicinal chemistry 20091008 |
Capecitabine in combination with irinotecan (XELIRI), administered as a 2-weekly schedule, as first-line chemotherapy for patients with metastatic colorectal cancer: a phase II study of the Spanish GOTI group. | British journal of cancer 20091006 |
Effects of chronic celecoxib on testicular function in normal and lipopolysaccharide-treated rats. | International journal of andrology 20091001 |
Parecoxib has non-significant long-term effects on bone healing in rats when administered for a short period after fracture. | Archives of orthopaedic and trauma surgery 20091001 |
Patient preferences for the chemoprevention of colorectal cancer. | Digestive diseases and sciences 20091001 |
Regulation of peroxisome proliferator-activated receptor-beta/delta by the APC/beta-CATENIN pathway and nonsteroidal antiinflammatory drugs. | Molecular carcinogenesis 20091001 |
Dystrophic (senescent) rather than activated microglial cells are associated with tau pathology and likely precede neurodegeneration in Alzheimer's disease. | Acta neuropathologica 20091001 |
Selective and non-selective non-steroidal anti-inflammatory drugs and the risk of acute kidney injury. | Pharmacoepidemiology and drug safety 20091001 |
Cellular membranes function as a storage compartment for celecoxib. | Journal of molecular medicine (Berlin, Germany) 20091001 |
Inhibition of cyclooxygenase-2 suppresses lymph node metastasis via VEGF-C. | Anatomical record (Hoboken, N.J. : 2007) 20091001 |
Celecoxib reduces symptoms in men with difficult chronic pelvic pain syndrome (Category IIIA). | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20091001 |
The effects of celecoxib, a COX-2 selective inhibitor, on acute inflammation induced in irradiated rats. | Inflammopharmacology 20091001 |
Differential effects of non-steroidal anti-inflammatory drugs on mitochondrial dysfunction during oxidative stress. | Archives of biochemistry and biophysics 20091001 |
[Inhibiting cyclooxygenase and 5-lipoxygenase activities is an anti-inflammatory mechanism of Huzhang Gout Granule]. | Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20091001 |
Cyclin-mediated G1 arrest by celecoxib differs in low-versus high-grade bladder cancer. | Anticancer research 20091001 |
Delayed onset nodules from liquid injectable silicone: report of a case, evaluation of associated histopathology and results of treatment with minocycline and celocoxib. | Journal of drugs in dermatology : JDD 20091001 |
A comparison of the effects of ibuprofen and rofecoxib on rabbit fibula osteotomy healing. | Acta orthopaedica 20091001 |
A reciprocal relationship exists between non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) and cyclooxygenase-2. | Cancer letters 20090918 |
Adjuvant therapy with oral sodium clodronate in locally advanced and metastatic prostate cancer: long-term overall survival results from the MRC PR04 and PR05 randomised controlled trials. | The Lancet. Oncology 20090909 |
Enhanced killing of chemo-resistant breast cancer cells via controlled aggravation of ER stress. | Cancer letters 20090908 |
Therapeutic effect of Aralia cordata extracts on cartilage protection in collagenase-induced inflammatory arthritis rabbit model. | Journal of ethnopharmacology 20090907 |
Research Ethics . In clear sight. | BMJ (Clinical research ed.) 20090902 |
The role of celecoxib in Rad51 expression and cell survival affected by gefitinib in human non-small cell lung cancer cells. | Lung cancer (Amsterdam, Netherlands) 20090901 |
Kaposiform hemangioendothelioma in multiple spinal levels without skin changes. | Clinical orthopaedics and related research 20090901 |
Fenbufen based 3-[5-(substituted aryl)-1,3,4-oxadiazol-2-yl]-1-(biphenyl-4-yl)propan-1-ones as safer antiinflammatory and analgesic agents. | European journal of medicinal chemistry 20090901 |
Prediction of food effects on the absorption of celecoxib based on biorelevant dissolution testing coupled with physiologically based pharmacokinetic modeling. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20090901 |
Recruitment strategies for a lung cancer chemoprevention trial involving ex-smokers. | Contemporary clinical trials 20090901 |
Celecoxib enhanced the sensitivity of cancer cells to anticancer drugs by inhibition of the expression of P-glycoprotein through a COX-2-independent manner. | Journal of cellular biochemistry 20090901 |
The search for new COX-2 inhibitors: a review of 2002 - 2008 patents. | Expert opinion on therapeutic patents 20090901 |
Anti-inflammatory, anti-proliferative and antioxidant profiles of selective cyclooxygenase-2 inhibition as chemoprevention for rat bladder carcinogenesis. | Cancer biology & therapy 20090901 |
Adding gabapentin to a multimodal regimen does not reduce acute pain, opioid consumption or chronic pain after total hip arthroplasty. | Acta anaesthesiologica Scandinavica 20090901 |
Effect of selective inhibitors of inflammation on oral mucositis: preclinical studies. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20090901 |
Early response to COX-2 inhibitors as a predictor of overall response in osteoarthritis: pooled results from two identical trials comparing etoricoxib, celecoxib and placebo. | Rheumatology (Oxford, England) 20090901 |
Preparation and evaluation of celecoxib-loaded microcapsules with self-microemulsifying core. | Journal of microencapsulation 20090901 |
Modulation of ionizing radiation-induced G2 arrest by cyclooxygenase-2 and its inhibitor celecoxib. | International journal of radiation oncology, biology, physics 20090901 |
Structure activity relationship of antiproliferative agents using multiple linear regression. | Chemical biology & drug design 20090901 |
Study on mechanism for amorphous drug stabilization using gelucire 50/13. | Chemical & pharmaceutical bulletin 20090901 |
18F-FLT and 18F-FDG PET to measure response to radiotherapy combined with celecoxib in two colorectal xenograft models. | International journal of radiation biology 20090901 |
Regression of recurrent respiratory papillomatosis with celecoxib and erlotinib combination therapy. | Chest 20090901 |
Cost-utility of celecoxib use in different treatment strategies for osteoarthritis and rheumatoid arthritis from the Quebec healthcare system perspective. | Journal of medical economics 20090901 |
Celecoxib antagonizes perifosine's anticancer activity involving a cyclooxygenase-2-dependent mechanism. | Molecular cancer therapeutics 20090901 |
Cyclooxygenase 2 modulates killing of cytotoxic T lymphocytes by colon cancer cells. | Journal of clinical biochemistry and nutrition 20090901 |
Preliminary trial of rebamipide for prevention of low-dose aspirin-induced gastric injury in healthy subjects: a randomized, double-blind, placebo-controlled, cross-over study. | Journal of clinical biochemistry and nutrition 20090901 |
[Chemoprevention of Barrett's esophagus by celecoxib in rats]. | Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20090901 |
The impact of neuroimmune dysregulation on neuroprotection and neurotoxicity in psychiatric disorders--relation to drug treatment. | Dialogues in clinical neuroscience 20090901 |
Trial publication after registration in ClinicalTrials.Gov: a cross-sectional analysis. | PLoS medicine 20090901 |
Genetic polymorphism of the human cytochrome P450 2C9 gene and its clinical significance. | Current drug metabolism 20090901 |
[The effect of simultaneously blocking target epidermal growth factor receptor tyrosine kinase and cyclooxygenase-2 on the growth of NPC cell]. | Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 20090901 |
Synthesis, ex vivo and in vitro hydrolysis study of an indoline derivative designed as an anti-inflammatory with reduced gastric ulceration properties. | Molecules (Basel, Switzerland) 20090826 |
Celecoxib-induced cholestatic liver failure requiring orthotopic liver transplantation. | World journal of gastroenterology 20090821 |
Two phase II trials of temozolomide with interferon-alpha2b (pegylated and non-pegylated) in patients with recurrent glioblastoma multiforme. | British journal of cancer 20090818 |
Effects of short-term acetaminophen and celecoxib treatment on orthodontic tooth movement and neuronal activation in rat. | Brain research bulletin 20090814 |
Regulation of the apoptosis-inducing kinase DRAK2 by cyclooxygenase-2 in colorectal cancer. | British journal of cancer 20090804 |
Celecoxib and exemestane versus placebo and exemestane in postmenopausal metastatic breast cancer patients: a double-blind phase III GINECO study. | Breast cancer research and treatment 20090801 |
Topical chemoprevention of skin cancer in mice, using combined inhibitors of 5-lipoxygenase and cyclo-oxygenase-2. | The Journal of laryngology and otology 20090801 |
Eggshell membrane in the treatment of pain and stiffness from osteoarthritis of the knee: a randomized, multicenter, double-blind, placebo-controlled clinical study. | Clinical rheumatology 20090801 |
Global variation in CYP2C8-CYP2C9 functional haplotypes. | The pharmacogenomics journal 20090801 |
Metronomic chemotherapy-induced bilateral subdural hematoma in a child with meningeal carcinomatosis. | Pediatric blood & cancer 20090801 |
Inflammation and the phenomenology, pathophysiology, comorbidity, and treatment of bipolar disorder: a systematic review of the literature. | The Journal of clinical psychiatry 20090801 |
Subcellular movement and expression of HSP27, alphaB-crystallin, and HSP70 after two bouts of eccentric exercise in humans. | Journal of applied physiology (Bethesda, Md. : 1985) 20090801 |
Inability of celecoxib to prevent fibrosis in bile duct-ligated rat liver. | Liver international : official journal of the International Association for the Study of the Liver 20090801 |
Identification of [4-[4-(methylsulfonyl)phenyl]-6-(trifluoromethyl)-2-pyrimidinyl] amines and ethers as potent and selective cyclooxygenase-2 inhibitors. | Bioorganic & medicinal chemistry letters 20090801 |
The hepatic safety and tolerability of the cyclooxygenase-2 selective NSAID celecoxib: pooled analysis of 41 randomized controlled trials. | Current medical research and opinion 20090801 |
An update on the efficacy of non-steroidal anti-inflammatory drugs in Alzheimer's disease. | Expert opinion on investigational drugs 20090801 |
Design and synthesis of new 1,3-benzthiazinan-4-one derivatives as selective cyclooxygenase (COX-2) inhibitors. | Bioorganic & medicinal chemistry 20090801 |
Clinical and pharmacodynamic evaluation of metronomic cyclophosphamide, celecoxib, and dexamethasone in advanced hormone-refractory prostate cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090801 |
First experiences with low-dose anti-angiogenic treatment in gliomatosis cerebri with signs of angiogenic activity. | Anticancer research 20090801 |
Cyclooxygenase-2 (COX-2) negatively regulates expression of epidermal growth factor receptor and causes resistance to gefitinib in COX-2-overexpressing cancer cells. | Molecular cancer research : MCR 20090801 |
Regression of follicular lymphoma with Devil's Claw: coincidence or causation? | Current oncology (Toronto, Ont.) 20090801 |
Selective cyclooxygenase-2 inhibition reduces endothelial dysfunction and improves inflammatory status in patients with intermittent claudication. | Revista espanola de cardiologia 20090801 |
Celecoxib potentiates the anticancer effect of cisplatin on vulvar cancer cells independently of cyclooxygenase. | Annals of the New York Academy of Sciences 20090801 |
[Multimodal effect of celecoxib on the perioperative analgesia in orthopaedic surgery]. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20090801 |
[Effect of Celecoxib on cycloxygenase-2 expression and inducing apoptosis in Tca8113 cell lines]. | Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology 20090801 |
[Effects of celecoxib on the proliferation and apoptosis of human nasopharyngeal carcinoma cell line CNE-2]. | Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 20090801 |
Anti-inflammatory effects of low molecular weight heparin derivative in a rat model of carrageenan-induced pleurisy. | Journal of cellular and molecular medicine 20090801 |
1-(3,5-Dimethyl-1H-pyrazol-1-yl)-3-phenyl-isoquinoline. | Acta crystallographica. Section E, Structure reports online 20090801 |
Kinetic cell-based morphological screening: prediction of mechanism of compound action and off-target effects. | Chemistry & biology 20090731 |
Etoricoxib: a review of its use in the symptomatic treatment of osteoarthritis, rheumatoid arthritis, ankylosing spondylitis and acute gouty arthritis. | Drugs 20090730 |
Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-carboxymethylphenyl)-1-(4-methanesulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its aminosulfonyl analog: Synthesis, biological evaluation and nitric oxide release studies. | Bioorganic & medicinal chemistry 20090715 |
Carbonic anhydrase inhibitors. Inhibition studies of a coral secretory isoform by sulfonamides. | Bioorganic & medicinal chemistry 20090715 |
Synthesis, biological evaluation and docking studies of novel benzopyranone congeners for their expected activity as anti-inflammatory, analgesic and antipyretic agents. | Bioorganic & medicinal chemistry 20090715 |
Synthesis and biological evaluation of new 4-carboxyl quinoline derivatives as cyclooxygenase-2 inhibitors. | Bioorganic & medicinal chemistry 20090715 |
Advantages of celecoxib nanosuspension formulation and transformation into tablets. | International journal of pharmaceutics 20090706 |
Anticancer effect of celecoxib via COX-2 dependent and independent mechanisms in human gastric cancers cells. | Digestive diseases and sciences 20090701 |
Mechanism of action of celecoxib on normal and acid-challenged gastric mucosa. | Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie 20090701 |
Antagonism by haloperidol and its metabolites of mechanical hypersensitivity induced by intraplantar capsaicin in mice: role of sigma-1 receptors. | Psychopharmacology 20090701 |
Synergistic inhibition effect of tumor growth by using celecoxib in combination with oxaliplatin. | Cancer investigation 20090701 |
Down-regulation of the HGF/MET autocrine loop induced by celecoxib and mediated by P-gp in MDR-positive human hepatocellular carcinoma cell line. | Biochemical pharmacology 20090701 |
Carbonic anhydrase inhibitors. Inhibition and homology modeling studies of the fungal beta-carbonic anhydrase from Candida albicans with sulfonamides. | Bioorganic & medicinal chemistry 20090701 |
Chronic pretreatment with celecoxib reduces infarct size. | Journal of cardiovascular pharmacology 20090701 |
Prostaglandin E(2) synthase inhibition as a therapeutic target. | Expert opinion on therapeutic targets 20090701 |
Effects of steroidal and nonsteroidal drugs on tooth movement and root resorption in the rat molar. | The Angle orthodontist 20090701 |
Effect of cyclooxygenase-2 on ischemic preconditioning of skin flaps. | Annals of plastic surgery 20090701 |
Lymphoblastic T-cell lymphoma in mice is unaffected by Celecoxib as single agent or in combination with cyclophosphamide. | Leukemia & lymphoma 20090701 |
Cyclooxygenase-2 up-regulates ataxia telangiectasia and Rad3 related through extracellular signal-regulated kinase activation. | Molecular cancer research : MCR 20090701 |
Harvesting candidate genes responsible for serious adverse drug reactions from a chemical-protein interactome. | PLoS computational biology 20090701 |
[Study on the mechanism of preventing alcholic liver disease by selective cyclooxygenase 2 inhibitor]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20090701 |
Cardiovascular safety of celecoxib in acute myocardial infarction patients: a nested case-control study. | Heart international 20090630 |
Protective effects of butanol fraction from Betula platyphyla var. japonica on cartilage alterations in a rabbit collagenase-induced osteoarthritis. | Journal of ethnopharmacology 20090625 |
Dipyridamole inhibits cobalt chloride-induced osteopontin expression in NRK52E cells. | European journal of pharmacology 20090624 |
Pharmacological modulation of movement-evoked pain in a rat model of osteoarthritis. | European journal of pharmacology 20090624 |
Comparing safety and efficacy of first-line irinotecan/fluoropyrimidine combinations in elderly versus nonelderly patients with metastatic colorectal cancer: findings from the bolus, infusional, or capecitabine with camptostar-celecoxib study. | Cancer 20090615 |
Design and synthesis of 3-alkyl-2-aryl-1,3-thiazinan-4-one derivatives as selective cyclooxygenase (COX-2) inhibitors. | Bioorganic & medicinal chemistry letters 20090615 |
Pattern recognition analysis for the prediction of adverse effects by nonsteroidal anti-inflammatory drugs using 1H NMR-based metabolomics in rats. | Analytical chemistry 20090615 |
Changes in gene expression predicting local control in cervical cancer: results from Radiation Therapy Oncology Group 0128. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090615 |
Anti-Helicobacter pylori therapy followed by celecoxib on progression of gastric precancerous lesions. | World journal of gastroenterology 20090614 |
Chronic treatment with celecoxib reverses chronic unpredictable stress-induced depressive-like behavior via reducing cyclooxygenase-2 expression in rat brain. | European journal of pharmacology 20090610 |
T-regulatory cell modulation: the future of cancer immunotherapy? | British journal of cancer 20090602 |
A multicenter phase II study of the combination of oxaliplatin, irinotecan and capecitabine in the first-line treatment of metastatic colorectal cancer. | British journal of cancer 20090602 |
Treatment in advanced colorectal cancer: what, when and how? | British journal of cancer 20090602 |
Enhancement of the action of the antivascular drug 5,6-dimethylxanthenone-4-acetic acid (DMXAA; ASA404) by non-steroidal anti-inflammatory drugs. | Investigational new drugs 20090601 |
Efficacy of signal pathway inhibitors alone and in combination with Cisplatin varies between human non-small cell lung cancer lines. | The Journal of surgical research 20090601 |
Experimental rat bladder urothelial cell carcinoma models. | World journal of urology 20090601 |
Cytochrome P450 2C9 variants influence response to celecoxib for prevention of colorectal adenoma. | Gastroenterology 20090601 |
Functional coupling expression of COX-2 and cPLA2 induced by ATP in rat vascular smooth muscle cells: role of ERK1/2, p38 MAPK, and NF-kappaB. | Cardiovascular research 20090601 |
COX-2-mediated inflammation in fat is crucial for obesity-linked insulin resistance and fatty liver. | Obesity (Silver Spring, Md.) 20090601 |
The impact of selective and non-selective non-steroid anti-inflammatory drugs on secondary hemostasis in healthy volunteers. | Thrombosis research 20090601 |
Anti-tumoral effect of a celecoxib low dose on a model of human medullary thyroid cancer in nude mice. | Thyroid : official journal of the American Thyroid Association 20090601 |
Hepatic stellate cells promote hepatocyte engraftment in rat liver after prostaglandin-endoperoxide synthase inhibition. | Gastroenterology 20090601 |
Desmoids: a revelation in biology and treatment. | Annals of surgical oncology 20090601 |
Genetically based impairment in CYP2C8- and CYP2C9-dependent NSAID metabolism as a risk factor for gastrointestinal bleeding: is a combination of pharmacogenomics and metabolomics required to improve personalized medicine? | Expert opinion on drug metabolism & toxicology 20090601 |
Cyclo-oxygenase 2 inhibitors and the risk of anastomotic leakage after fast-track colonic surgery. | The British journal of surgery 20090601 |
Nonsteroidal anti-inflammatory drugs and lower gastrointestinal complications. | Gastroenterology clinics of North America 20090601 |
Gastrocnemius vs. soleus strain: how to differentiate and deal with calf muscle injuries. | Current reviews in musculoskeletal medicine 20090601 |
What is the optimal therapy for patients with H5N1 influenza? | PLoS medicine 20090601 |
Trends in the molecular pathogenesis and clinical therapeutics of common neurodegenerative disorders. | International journal of molecular sciences 20090601 |
Epidemiology of Alzheimer's disease: occurrence, determinants, and strategies toward intervention. | Dialogues in clinical neuroscience 20090601 |
Mechanism-based treatments for Alzheimer's disease. | Dialogues in clinical neuroscience 20090601 |
The effects of cardiovascular risk factors on cognitive compromise. | Dialogues in clinical neuroscience 20090601 |
[Celecoxib promotes apoptosis of breast cancer cell line MDA-MB-231 through down-regulation of the NF-kappaB pathway]. | Ai zheng = Aizheng = Chinese journal of cancer 20090601 |
Celecoxib in the treatment of primary dysmenorrhea: results from two randomized, double-blind, active- and placebo-controlled, crossover studies. | Clinical therapeutics 20090601 |
3-(3-Chloro-anilino)-1-(3,5-dimethyl-1H-pyrazol-1-yl)propan-1-one. | Acta crystallographica. Section E, Structure reports online 20090601 |
Celecoxib enhances the detoxification of diethylnitrosamine in rat liver cancer. | World journal of gastroenterology 20090521 |
Prophylactic ciprofloxacin treatment prevented high mortality, and modified systemic and intestinal immune function in tumour-bearing rats receiving dose-intensive CPT-11 chemotherapy. | British journal of cancer 20090519 |
Effect of dietary and topical Celecoxib on expression of bcl-2, bax, c-erb-B2 and Ki67 in carcinogen-induced tongue carcinoma in rat. | Pakistan journal of biological sciences : PJBS 20090515 |
Carbonic anhydrase inhibitors. Cloning, characterization, and inhibition studies of a new beta-carbonic anhydrase from Mycobacterium tuberculosis. | Journal of medicinal chemistry 20090514 |
Cyclooxygenase inhibitors differentially modulate p73 isoforms in neuroblastoma. | Oncogene 20090514 |
The balance between severe cardiovascular and gastrointestinal events among users of selective and non-selective non-steroidal anti-inflammatory drugs. | Annals of the rheumatic diseases 20090501 |
Phase I and pharmacokinetic study of mitomycin C and celecoxib as potential modulators of tumor resistance to irinotecan in patients with solid malignancies. | Cancer chemotherapy and pharmacology 20090501 |
Salvianolic acid B inhibits growth of head and neck squamous cell carcinoma in vitro and in vivo via cyclooxygenase-2 and apoptotic pathways. | International journal of cancer 20090501 |
Synthesis, pharmacological evaluation and docking studies of new sulindac analogues. | European journal of medicinal chemistry 20090501 |
Characterization and pharmacological evaluation of febrile response on zymosan-induced arthritis in rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20090501 |
Inflammatory mediators released following application of irritants on the rat injured incisors. The effect of treatment with anti-inflammatory drugs. | Cytokine 20090501 |
Phase II study of celecoxib with cisplatin plus etoposide in extensive-stage small cell lung cancer. | Cancer investigation 20090501 |
Postoperative recovery profile after elective abdominal hysterectomy: a prospective, observational study of a multimodal anaesthetic regime. | European journal of anaesthesiology 20090501 |
The additional loss of Bak and not the lack of the protein tyrosine kinase p56/Lck in one JCaM1.6 subclone caused pronounced apoptosis resistance in response to stimuli of the intrinsic pathway. | Apoptosis : an international journal on programmed cell death 20090501 |
The importance of brain PGE2 inhibition versus paw PGE2 inhibition as a mechanism for the separation of analgesic and antipyretic effects of lornoxicam in rats with paw inflammation. | The Journal of pharmacy and pharmacology 20090501 |
Subacute pain and function after fast-track hip and knee arthroplasty. | Anaesthesia 20090501 |
Effects of non-cytotoxic drugs on the growth of multidrug-resistance human gastric carcinoma cell line. | Journal of digestive diseases 20090501 |
Spindle epithelial tumor with thymus-like elements of the thyroid: a multi-institutional case series and review of the literature. | Journal of pediatric surgery 20090501 |
A randomized controlled trial investigating the effects of celecoxib in patients with localized prostate cancer. | Anticancer research 20090501 |
Cyclooxygenase-2 inhibitor celecoxib in a rat model of hindlimb ischemia reperfusion. | Canadian journal of physiology and pharmacology 20090501 |
Cardiovascular risks of nonsteroidal antiinflammatory drugs in patients after hospitalization for serious coronary heart disease. | Circulation. Cardiovascular quality and outcomes 20090501 |
Importance of cyclooxygenase 2-mediated low-grade inflammation in the development of fructose-induced insulin resistance in rats. | The Chinese journal of physiology 20090430 |
Anti-inflammatory drugs suppress proliferation and induce apoptosis through altering expressions of cell cycle regulators and pro-apoptotic factors in cultured human osteoblasts. | Toxicology 20090428 |
Molecular cloning, characterization, and inhibition studies of the Rv1284 beta-carbonic anhydrase from Mycobacterium tuberculosis with sulfonamides and a sulfamate. | Journal of medicinal chemistry 20090423 |
Effects of celecoxib on volumes of hematoma and edema in patients with primary intracerebral hemorrhage. | Journal of the neurological sciences 20090415 |
Synthesis and anti-inflammatory activity of the major metabolites of imrecoxib. | Bioorganic & medicinal chemistry letters 20090415 |
Determination of two COX-2 inhibitors in serum and synovial fluid of patients with inflammatory arthritis by ultra performance liquid chromatography-inductively coupled plasma mass spectroscopy and quadrupole time-of-flight mass spectrometry. | Journal of pharmaceutical and biomedical analysis 20090405 |
The chondroprotective effect of selective COX-2 inhibition in osteoarthritis: ex vivo evaluation of human cartilage tissue after in vivo treatment. | Osteoarthritis and cartilage 20090401 |
Celecoxib exacerbates hepatic fibrosis and induces hepatocellular necrosis in rats treated with porcine serum. | Prostaglandins & other lipid mediators 20090401 |
COX-2 expression in highly aggressive thyroid malignancies - indication for a possible therapeutic option? | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20090401 |
Evaluation of different methods used to assess disease activity in rheumatoid arthritis: analyses of abatacept clinical trial data. | Annals of the rheumatic diseases 20090401 |
Prediction of the effects of genetic polymorphism on the pharmacokinetics of CYP2C9 substrates from in vitro data. | Pharmaceutical research 20090401 |
Mechanisms operated by endothelin ETA and ETB receptors in the trigeminal ganglion contribute to orofacial thermal hyperalgesia induced by infraorbital nerve constriction in rats. | Neuropeptides 20090401 |
Gemcitabine, irinotecan and celecoxib in patients with biliary cancer. | Anti-cancer drugs 20090401 |
A randomized, placebo-controlled study of the effects of naproxen, aspirin, celecoxib or clopidogrel on gastroduodenal mucosal healing. | Alimentary pharmacology & therapeutics 20090401 |
Role of systemic and local administration of selective inhibitors of cyclo-oxygenase 1 and 2 in an experimental model of periodontal disease in rats. | Journal of periodontal research 20090401 |
Role of combination therapy with aromatase and cyclooxygenase-2 inhibitors in patients with metastatic breast cancer. | Annals of oncology : official journal of the European Society for Medical Oncology 20090401 |
Mechanisms underlying the nociceptive responses induced by platelet-activating factor (PAF) in the rat paw. | Biochemical pharmacology 20090401 |
Celecoxib-associated anaphylaxis. | The Annals of pharmacotherapy 20090401 |
Induction of prostaglandin E2 pathway promotes gastric hamartoma development with suppression of bone morphogenetic protein signaling. | Cancer research 20090401 |
The human cytomegalovirus-encoded chemokine receptor US28 promotes angiogenesis and tumor formation via cyclooxygenase-2. | Cancer research 20090401 |
Rationale, design, and governance of Prospective Randomized Evaluation of Celecoxib Integrated Safety versus Ibuprofen Or Naproxen (PRECISION), a cardiovascular end point trial of nonsteroidal antiinflammatory agents in patients with arthritis. | American heart journal 20090401 |
New, long-term insights from the Adenoma Prevention with Celecoxib Trial on a promising but troubled class of drugs. | Cancer prevention research (Philadelphia, Pa.) 20090401 |
Levels of prostaglandin E metabolite and leukotriene E(4) are increased in the urine of smokers: evidence that celecoxib shunts arachidonic acid into the 5-lipoxygenase pathway. | Cancer prevention research (Philadelphia, Pa.) 20090401 |
Five-year efficacy and safety analysis of the Adenoma Prevention with Celecoxib Trial. | Cancer prevention research (Philadelphia, Pa.) 20090401 |
Cyclooxygenase-2 (cox-2) blockade in the chemoprevention of cancers of the colon, breast, prostate, and lung. | Inflammopharmacology 20090401 |
Etodolac attenuates mechanical allodynia in a mouse model of neuropathic pain. | Journal of pharmacological sciences 20090401 |
Can treatment with nonsteroidal anti-inflammatory drugs protect from dementia? | Archives of neurology 20090401 |
Economic evaluation of nonsteroidal anti-inflammatory drug strategies in rheumatoid arthritis. | International journal of technology assessment in health care 20090401 |
Prevention of seizure-induced up-regulation of endothelial P-glycoprotein by COX-2 inhibition. | Neuropharmacology 20090401 |
Enhanced anti-inflammatory effects of celecoxib from a transdermally applied nanoemulsion. | Die Pharmazie 20090401 |
[Short-term preoperative treatment of celecoxib, a selective cyclooxygenase-2 inhibitor, on E-cadherin expression in gastric carcinoma tissues]. | Ai zheng = Aizheng = Chinese journal of cancer 20090401 |
Cases of pediatric ingestion of celecoxib reported to Texas poison control centers in 2000-2007. | Human & experimental toxicology 20090401 |
Matrine suppresses breast cancer cell proliferation and invasion via VEGF-Akt-NF-kappaB signaling. | Cytotechnology 20090401 |
A role for cyclooxygenase-1 in beta-amyloid-induced neuroinflammation. | Aging 20090401 |
AMP kinase/cyclooxygenase-2 pathway regulates proliferation and apoptosis of cancer cells treated with quercetin. | Experimental & molecular medicine 20090331 |
Synthesis of celecoxib analogues possessing a N-difluoromethyl-1,2-dihydropyrid-2-one 5-lipoxygenase pharmacophore: biological evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity. | Journal of medicinal chemistry 20090326 |
A phase II study of celecoxib in combination with paclitaxel, carboplatin, and radiotherapy for patients with inoperable stage IIIA/B non-small cell lung cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20090315 |
Prominent celecoxib researcher admits fabricating data in 21 articles. | BMJ (Clinical research ed.) 20090309 |
Non-steroidal anti-inflammatory drug use does not appear to be associated with increased cardiovascular mortality in patients with inflammatory polyarthritis: results from a primary care based inception cohort of patients. | Annals of the rheumatic diseases 20090301 |
In vitro and in vivo inhibitory effect evaluation of cyclooxygenase-2 inhibitors, antisense cyclooxygenase-2 cDNA, and their combination on the growth of human bladder cancer cells. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20090301 |
Anti-gastric cancer effects of celecoxib, a selective COX-2 inhibitor, through inhibition of Akt signaling. | Journal of gastroenterology and hepatology 20090301 |
Combined action of celecoxib and ionizing radiation in prostate cancer cells is independent of pro-apoptotic Bax. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20090301 |
Mechanisms involved in the rat peritoneal leukocyte migration induced by a Kunitz-type inhibitor isolated from Dimorphandra mollis seeds. | Toxicon : official journal of the International Society on Toxinology 20090301 |
Cyclooxygenase-2 mediates dialysate-induced alterations of the peritoneal membrane. | Journal of the American Society of Nephrology : JASN 20090301 |
The analgesic actions of centrally administered celecoxib are mediated by endogenous opioids. | Pain 20090301 |
Inhibition of iNOS and COX-2 in human whole blood ex vivo and monocyte-macrophage J774 cells by a new group of aminothiopyrimidone derivatives. | Bioorganic & medicinal chemistry 20090301 |
Pooled analysis of GI tolerability of 21 randomized controlled trials of celecoxib and nonselective NSAIDs. | Current medical research and opinion 20090301 |
Meeting the challenge of influenza pandemic preparedness in developing countries. | Emerging infectious diseases 20090301 |
Molecular targets for cancer chemoprevention. | Nature reviews. Drug discovery 20090301 |
Synthesis and biological evaluation of novel pyrazole derivatives as anti-inflammatory antimicrobial agents. | Medicinal chemistry (Shariqah (United Arab Emirates)) 20090301 |
Efficacy of celecoxib on controlling irregular uterine bleeding secondary to Jadelle use. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20090301 |
[Effects of celecoxib on PGE2 synthesis and COX-2 and VEGF-C mRNA expression in Tca8113 cell lines]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20090301 |
Nitrooxymethyl-substituted analogues of celecoxib: synthesis and pharmacological characterization. | Chemistry & biodiversity 20090301 |
Alzheimer's Disease Anti-inflammatory Prevention Trial: design, methods, and baseline results. | Alzheimer's & dementia : the journal of the Alzheimer's Association 20090301 |
Selective cyclooxygenase-2 inhibition protects against myocardial damage in experimental acute ischemia. | Clinics (Sao Paulo, Brazil) 20090301 |
Celecoxib does not delay cutaneous wound healing in haemophilia B mice. | Haemophilia : the official journal of the World Federation of Hemophilia 20090301 |
Comparison of the effectiveness of six and two acupuncture point regimens in osteoarthritis of the knee: a randomised trial. | Acupuncture in medicine : journal of the British Medical Acupuncture Society 20090301 |
[Celecoxib enhances the lethal effects of bleomycin in human tongue squamous carcinoma cell line Tca8113]. | Zhonghua kou qiang yi xue za zhi = Zhonghua kouqiang yixue zazhi = Chinese journal of stomatology 20090301 |
Prostaglandin involvement in hyperthermia induced by sleep deprivation: a pharmacological and autoradiographic study. | Life sciences 20090227 |
Reactions of functionalized sulfonamides: application to lowering the lipophilicity of cytosolic phospholipase A2alpha inhibitors. | Journal of medicinal chemistry 20090226 |
Celecoxib does not appear to affect prosthesis fixation in total knee replacement: A randomized study using radiostereometry in 50 patients. | Acta orthopaedica 20090226 |
Silica-lipid hybrid (SLH) microcapsules: a novel oral delivery system for poorly soluble drugs. | Journal of controlled release : official journal of the Controlled Release Society 20090220 |
Up-regulation of S100P expression by non-steroidal anti-inflammatory drugs and its role in anti-tumorigenic effects. | The Journal of biological chemistry 20090213 |
Non-steroidal anti-inflammatory drugs and risk of gastric and oesophageal adenocarcinomas: results from a cohort study and a meta-analysis. | British journal of cancer 20090210 |
Effects of nonselective and selective cyclooxygenase inhibitors on small intestinal motility in the horse. | Research in veterinary science 20090201 |
Raft aggregation with specific receptor recruitment is required for microglial phagocytosis of Abeta42. | Glia 20090201 |
Inflammatory processes of prostate tissue microenvironment drive rat prostate carcinogenesis: preventive effects of celecoxib. | The Prostate 20090201 |
Cyclooxygenase-2 inhibition increases lipopolysaccharide-induced atherosclerosis in mice. | Cardiovascular research 20090201 |
Mechanism of drug release from polymethacrylate-based extrudates and milled strands prepared by hot-melt extrusion. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20090201 |
Effects of nicotine and lipopolysaccharide on the expression of matrix metalloproteinases, plasminogen activators, and their inhibitors in human osteoblasts. | Archives of oral biology 20090201 |
Risk of myocardial infarction and death associated with the use of nonsteroidal anti-inflammatory drugs (NSAIDs) among healthy individuals: a nationwide cohort study. | Clinical pharmacology and therapeutics 20090201 |
Effect of diabetes on transscleral delivery of celecoxib. | Pharmaceutical research 20090201 |
Systemic therapy for advancing or metastatic prostate cancer (STAMPEDE): a multi-arm, multistage randomized controlled trial. | BJU international 20090201 |
Efficacy and mechanism of action of KHBJ-9B, a new herbal medicine, and its major compound triterpenoids in human cartilage culture and in a rabbit model of collagenase-induced osteoarthritis. | International immunopharmacology 20090201 |
Carbonic anhydrase inhibitors: inhibition of the beta-class enzyme from the yeast Saccharomyces cerevisiae with sulfonamides and sulfamates. | Bioorganic & medicinal chemistry 20090201 |
Synthesis of 1-(methanesulfonyl- and aminosulfonylphenyl)acetylenes that possess a 2-(N-difluoromethyl-1,2-dihydropyridin-2-one) pharmacophore: evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity. | Bioorganic & medicinal chemistry letters 20090201 |
Antinociceptive effect of a novel tosylpyrazole compound in mice. | Basic & clinical pharmacology & toxicology 20090201 |
Synthesis and cyclooxygenase inhibition of various (aryl-1,2,3-triazole-1-yl)-methanesulfonylphenyl derivatives. | Bioorganic & medicinal chemistry 20090201 |
Prospective randomized study of 2 different techniques for endoscopic iliopsoas tendon release in the treatment of internal snapping hip syndrome. | Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association 20090201 |
Prevention of tumorigenesis in p53-null mammary epithelium by rexinoid bexarotene, tyrosine kinase inhibitor gefitinib, and celecoxib. | Cancer prevention research (Philadelphia, Pa.) 20090201 |
Identification of modulated genes by three classes of chemopreventive agents at preneoplastic stages in a p53-null mouse mammary tumor model. | Cancer prevention research (Philadelphia, Pa.) 20090201 |
Combination therapies that inhibit cyclooxygenase-2 and leukotriene synthesis prevent disease in murine collagen induced arthritis. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20090201 |
Inflammatory and oxidative stress markers in experimental crystalopathy: their modification by photostimulation. | Photomedicine and laser surgery 20090201 |
A short-term rat mammary carcinogenesis model for the prevention of hormonally responsive and nonresponsive in situ carcinomas. | Cancer prevention research (Philadelphia, Pa.) 20090201 |
Impressive regression of visceral and cerebral melanoma metastases under combination treatment including dacarbacine, radiotherapy and celecoxib. | International journal of dermatology 20090201 |
Colon cancer: preventive agents and the present status of chemoprevention. | Expert opinion on pharmacotherapy 20090201 |
Estrogen sulfotransferases in breast and endometrial cancers. | Annals of the New York Academy of Sciences 20090201 |
Bartter's syndrome with type 2 diabetes mellitus. | Journal of the Chinese Medical Association : JCMA 20090201 |
Celecoxib administration exhibits tissue specific effect on 3H-benzo(a)pyrene-DNA adduct formation in cigarette smoke inhaling mice. | Indian journal of experimental biology 20090201 |
[Effect of cyclooxygenase-2 on vascular endothelial cell apoptosis induced by cigarette smoke extract]. | Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases 20090201 |
Cyclooxygenase-1 null mice show reduced neuroinflammation in response to beta-amyloid. | Aging 20090201 |
Cyclo-oxygenase-1-selective inhibitor SC-560. | Acta crystallographica. Section E, Structure reports online 20090201 |
Kinetic modelling of NSAID action on COX-1: focus on in vitro/in vivo aspects and drug combinations. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20090131 |
Increased mortality and cardiovascular morbidity associated with use of nonsteroidal anti-inflammatory drugs in chronic heart failure. | Archives of internal medicine 20090126 |
Treatment for familial amyotrophic lateral sclerosis/motor neuron disease. | The Cochrane database of systematic reviews 20090121 |
Celecoxib plays a multiple role to peripheral blood lymphocytes and allografts in acute rejection in rats after cardiac transplantation. | Chinese medical journal 20090120 |
Differences in long-term disease activity and treatment of adult patients with childhood- and adult-onset systemic lupus erythematosus. | Arthritis and rheumatism 20090115 |
[Effects of perioperative administration of celecoxib on pain management and recovery of function after total knee replacement]. | Zhonghua wai ke za zhi [Chinese journal of surgery] 20090115 |
The antecedents of biliary cancer: a primary care case-control study in the United Kingdom. | British journal of cancer 20090113 |
Increased phospholipase A2 activity and inflammatory response but decreased nerve growth factor expression in the olfactory bulbectomized rat model of depression: effects of chronic ethyl-eicosapentaenoate treatment. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20090107 |
Suppression of Wnt/beta-catenin signaling inhibits prostate cancer cell proliferation. | European journal of pharmacology 20090105 |
The anti-inflammatory effect of celecoxib does not prevent liver fibrosis in bile duct-ligated rats. | Liver international : official journal of the International Association for the Study of the Liver 20090101 |
Potent cell growth inhibitory effects in hepatitis B virus X protein positive hepatocellular carcinoma cells by the selective cyclooxygenase-2 inhibitor celecoxib. | Molecular carcinogenesis 20090101 |
Celecoxib inhibits serum amyloid a-induced matrix metalloproteinase-10 expression in human endothelial cells. | Journal of vascular research 20090101 |
Inhibition of cyclooxygenase 2 expression by diallyl sulfide on joint inflammation induced by urate crystal and IL-1beta. | Osteoarthritis and cartilage 20090101 |
The selective COX-2 inhibitor celecoxib modulates sphingolipid synthesis. | Journal of lipid research 20090101 |
Combined preoperative use of celecoxib and gabapentin in the management of postoperative pain. | Aesthetic plastic surgery 20090101 |
Prostaglandin E2 acts via multiple receptors to regulate plasminogen-dependent proteolysis in the primate periovulatory follicle. | Endocrinology 20090101 |
Reversibility of aberrant global DNA and estrogen receptor-alpha gene methylation distinguishes colorectal precancer from cancer. | International journal of clinical and experimental pathology 20090101 |
Vascular permeability, neutrophil migration and edematogenic effects induced by the latex of Cryptostegia grandiflora. | Toxicon : official journal of the International Society on Toxinology 20090101 |
Synthesis and antiinflammatory activity of some new 1,3,5-trisubstituted pyrazolines bearing benzene sulfonamide. | Bioorganic & medicinal chemistry letters 20090101 |
A prospective study comparing celecoxib with naproxen in children with juvenile rheumatoid arthritis. | The Journal of rheumatology 20090101 |
Modeling using baseline characteristics in a small multicenter clinical trial for Barrett's esophagus. | Contemporary clinical trials 20090101 |
Discovery of novel analgesic and anti-inflammatory 3-arylamine-imidazo[1,2-a]pyridine symbiotic prototypes. | Bioorganic & medicinal chemistry 20090101 |
Expression pattern and functional relevance of epidermal growth factor receptor and cyclooxygenase-2: novel chemotherapeutic targets in pancreatic endocrine tumors? | The American journal of gastroenterology 20090101 |
Progression of pancreatic adenocarcinoma is significantly impeded with a combination of vaccine and COX-2 inhibition. | Journal of immunology (Baltimore, Md. : 1950) 20090101 |
Immune complex/Ig negatively regulate TLR4-triggered inflammatory response in macrophages through Fc gamma RIIb-dependent PGE2 production. | Journal of immunology (Baltimore, Md. : 1950) 20090101 |
Frequency of ill-founded off-label prescribing in Dutch general practice. | Pharmacoepidemiology and drug safety 20090101 |
Death following bilateral complete Achilles tendon rupture in a patient on fluoroquinolone therapy: a case report. | Journal of medical case reports 20090101 |
A review of the benefits and risks of nonsteroidal anti-inflammatory drugs in the management of mild-to-moderate osteoarthritis. | Osteopathic medicine and primary care 20090101 |
Hypothesis: primary antiangiogenic method proposed to treat early stage breast cancer. | BMC cancer 20090101 |
Augmented lung inflammation protects against influenza A pneumonia. | PloS one 20090101 |
Dramatic pain relief and resolution of bone inflammation following pamidronate in 9 pediatric patients with persistent chronic recurrent multifocal osteomyelitis (CRMO). | Pediatric rheumatology online journal 20090101 |
n3 and n6 polyunsaturated fatty acids differentially modulate prostaglandin E secretion but not markers of lipogenesis in adipocytes. | Nutrition & metabolism 20090101 |
Recent advances of novel targeted therapy in non-small cell lung cancer. | Journal of hematology & oncology 20090101 |
A randomized, multicentre, double-blind, parallel-group study to assess the adverse event-related discontinuation rate with celecoxib and diclofenac in elderly patients with osteoarthritis. | Scandinavian journal of rheumatology 20090101 |
Porcine sclera as a model of human sclera for in vitro transport experiments: histology, SEM, and comparative permeability. | Molecular vision 20090101 |
Amyotrophic lateral sclerosis. | Orphanet journal of rare diseases 20090101 |
Effects of celecoxib and nordihydroguaiaretic acid on puromycin aminonucleoside-induced nephrosis in the rat. | Journal of Korean medical science 20090101 |
The effect of selective cyclooxygenase-2 inhibitor on human osteoclast precursors to influence osteoclastogenesis in vitro. | Modern rheumatology 20090101 |
Does celecoxib have a role in the treatment of patients with colorectal cancer? | Clinical colorectal cancer 20090101 |
Developments in the clinical understanding of osteoarthritis. | Arthritis research & therapy 20090101 |
Metabolic profiling of the response to an oral glucose tolerance test detects subtle metabolic changes. | PloS one 20090101 |
Systematic review on quality control for drug management programs: is quality reported in the literature? | BMC health services research 20090101 |
Capecitabine and celecoxib as second-line treatment of advanced pancreatic and biliary tract cancers. | Oncology 20090101 |
Relationship between the expression of cyclooxygenase-2 and survivin in primary pterygium. | Molecular vision 20090101 |
Information about ADRs explored by pharmacovigilance approaches: a qualitative review of studies on antibiotics, SSRIs and NSAIDs. | BMC clinical pharmacology 20090101 |
A MT1-MMP/NF-kappaB signaling axis as a checkpoint controller of COX-2 expression in CD133+ U87 glioblastoma cells. | Journal of neuroinflammation 20090101 |
Asthmatic reaction induced by celecoxib in a patient with aspirin-induced asthma. | Journal of investigational allergology & clinical immunology 20090101 |
The immune tolerance of cancer is mediated by IDO that is inhibited by COX-2 inhibitors through regulatory T cells. | Journal of immunotherapy (Hagerstown, Md. : 1997) 20090101 |
Celecoxib and melatonin in prevention of female rat mammary carcinogenesis. | Neoplasma 20090101 |
Identification of novel cyclooxygenase-2-dependent genes in Helicobacter pylori infection in vivo. | Molecular cancer 20090101 |
Anti-inflammatory and antiarthritic effects of piperine in human interleukin 1beta-stimulated fibroblast-like synoviocytes and in rat arthritis models. | Arthritis research & therapy 20090101 |
Effects of celecoxib on the expression of osteoprotegerin, energy metabolism and cell viability in cultured human osteoblastic cells. | Clinical and experimental rheumatology 20090101 |
Passage and concentration-dependent effects of Indomethacin on tendon derived cells. | Journal of orthopaedic surgery and research 20090101 |
Competition between COX-2 inhibitors and some other drugs for binding sites on human serum albumin. | Drug metabolism and drug interactions 20090101 |
Effects of naltrexone on pain sensitivity and mood in fibromyalgia: no evidence for endogenous opioid pathophysiology. | PloS one 20090101 |
Antibiotic and anti-inflammatory use and the risk of prostate cancer. | BMC research notes 20090101 |
Prophylaxis of heterotopic ossification - an updated review. | Journal of orthopaedic surgery and research 20090101 |
Iatrogenic effects of COX-2 inhibitors in the US population: findings from the Medical Expenditure Panel Survey. | Drug safety 20090101 |
Interleukin-1beta and fibroblast growth factor receptor 1 cooperate to induce cyclooxygenase-2 during early mammary tumourigenesis. | Breast cancer research : BCR 20090101 |
t10c12 conjugated linoleic acid suppresses HER2 protein and enhances apoptosis in SKBr3 breast cancer cells: possible role of COX2. | PloS one 20090101 |
Apigenin, a non-mutagenic dietary flavonoid, suppresses lupus by inhibiting autoantigen presentation for expansion of autoreactive Th1 and Th17 cells. | Arthritis research & therapy 20090101 |
Data mining in pharmacovigilance--detecting the unexpected: the role of index of suspicion of the reporter. | Drug safety 20090101 |
[The effects of Celebrex on mammary tumorigenesis and aging in HER2/neu transgenic mice]. | Voprosy onkologii 20090101 |
Regular use of traditional analgesics predicts major coronary events: A cohort study. | Therapeutics and clinical risk management 20090101 |
Treatment and chemoprevention of NSAID-associated gastrointestinal complications. | Therapeutics and clinical risk management 20090101 |
Progress in spondylarthritis. Mechanisms of new bone formation in spondyloarthritis. | Arthritis research & therapy 20090101 |
IL-1beta stimulates the expression of prostaglandin receptor EP4 in human chondrocytes by increasing production of prostaglandin E2. | Connective tissue research 20090101 |
Label-free global serum proteomic profiling reveals novel celecoxib-modulated proteins in familial adenomatous polyposis patients. | Cancer genomics & proteomics 20090101 |
A gene expression profiling approach assessing celecoxib in a randomized controlled trial in prostate cancer. | Cancer genomics & proteomics 20090101 |
A phase II experience with neoadjuvant irinotecan (CPT-11), 5-fluorouracil (5-FU) and leucovorin (LV) for colorectal liver metastases. | BMC cancer 20090101 |
Pharmacological Treatment of Alzheimer's Disease: Is it Progressing Adequately? | The open neurology journal 20090101 |
The effect of newer anti-rheumatic drugs on osteogenic cell proliferation: an in-vitro study. | Journal of orthopaedic surgery and research 20090101 |
Multifocal fixed drug eruption due to celecoxib. | Dermatitis : contact, atopic, occupational, drug 20090101 |
Bilateral infraorbital nerve blocks decrease postoperative pain but do not reduce time to discharge following outpatient nasal surgery. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20090101 |
Role of aliskiren in cardio-renal protection and use in hypertensives with multiple risk factors. | Vascular health and risk management 20090101 |
Twelve years' experience with direct-to-consumer advertising of prescription drugs in Canada: a cautionary tale. | PloS one 20090101 |
Clinical trial of adjunctive celecoxib treatment in patients with major depression: a double blind and placebo controlled trial. | Depression and anxiety 20090101 |
Chemoprevention by celecoxib in reflux-induced gastric adenocarcinoma in Wistar rats that underwent gastrojejunostomy. | Acta cirurgica brasileira 20090101 |
Effects of rich-in-fat diets and highly selective COX-2 inhibitors on 7,12-dimethylbenz-(A)-anthracene-induced tumor growth. | International journal of immunopathology and pharmacology 20090101 |
Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. | Current medicinal chemistry 20090101 |
Issues in applying multi-arm multi-stage methodology to a clinical trial in prostate cancer: the MRC STAMPEDE trial. | Trials 20090101 |
Epidemiological studies in incidence, prevalence, mortality, and comorbidity of the rheumatic diseases. | Arthritis research & therapy 20090101 |
Ultra low-dose naloxone and tramadol/acetaminophen in elderly patients undergoing joint replacement surgery: a pilot study. | Pain research & management 20090101 |
Preclinical safety pharmacological studies on the amorphous formulation of celecoxib. | Arzneimittel-Forschung 20090101 |
Discrepancy among observational studies: example of naproxen-associated adverse events. | The open rheumatology journal 20090101 |
Gabapentin decreases morphine consumption and improves functional recovery following total knee arthroplasty. | Pain research & management 20090101 |
Treatment of pediatric pulmonary hypertension. | Vascular health and risk management 20090101 |
Eggshell membrane: a possible new natural therapeutic for joint and connective tissue disorders. Results from two open-label human clinical studies. | Clinical interventions in aging 20090101 |
Barrett's esophagus: where do we stand? | Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association 20090101 |
Essentials for starting a pediatric clinical study (4): Clinical pediatric safety planning based on preclinical toxicity studies and pediatric pharmacovigilance guidance. | The Journal of toxicological sciences 20090101 |
Whole genome expression analysis within the angiotensin II-apolipoprotein E deficient mouse model of abdominal aortic aneurysm. | BMC genomics 20090101 |
Single dose oral etodolac for acute postoperative pain in adults. | The Cochrane database of systematic reviews 20090101 |
Molecular fingerprinting of radiation resistant tumors: can we apprehend and rehabilitate the suspects? | BMC cancer 20090101 |
Molecular therapies for systemic lupus erythematosus: clinical trials and future prospects. | Arthritis research & therapy 20090101 |
Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations. | Journal of translational medicine 20090101 |
Cost effectiveness of COX 2 selective inhibitors and traditional NSAIDs alone or in combination with a proton pump inhibitor for people with osteoarthritis. | BMJ (Clinical research ed.) 20090101 |
Examination of effects of GSK3beta phosphorylation, beta-catenin phosphorylation, and beta-catenin degradation on kinetics of Wnt signaling pathway using computational method. | Theoretical biology & medical modelling 20090101 |
An exploration of the ability of tepoxalin to ameliorate the degradation of articular cartilage in a canine in vitro model. | BMC veterinary research 20090101 |
Gastroesophageal reflux leads to esophageal cancer in a surgical model with mice. | BMC gastroenterology 20090101 |
TNF-alpha mediated apoptosis plays an important role in the development of early diabetic retinopathy and long-term histopathological alterations. | Molecular vision 20090101 |
Breast-cancer-associated metastasis is significantly increased in a model of autoimmune arthritis. | Breast cancer research : BCR 20090101 |
Are all n-3 polyunsaturated fatty acids created equal? | Lipids in health and disease 20090101 |
Antisense gapmers selectively suppress individual oncogenic p73 splice isoforms and inhibit tumor growth in vivo. | Molecular cancer 20090101 |
A novel approach to management of nocturia in patients with benign prostatic hyperplasia. | Indian journal of urology : IJU : journal of the Urological Society of India 20090101 |
Multiparameter phospho-flow analysis of lymphocytes in early rheumatoid arthritis: implications for diagnosis and monitoring drug therapy. | PloS one 20090101 |
Biomolecular markers in cancer of the tongue. | Journal of oncology 20090101 |
Enhanced sensitivity of celecoxib in human glioblastoma cells: Induction of DNA damage leading to p53-dependent G1 cell cycle arrest and autophagy. | Molecular cancer 20090101 |
Rho iso-alpha acids from hops inhibit the GSK-3/NF-kappaB pathway and reduce inflammatory markers associated with bone and cartilage degradation. | Journal of inflammation (London, England) 20090101 |
Health-state utilities in a prisoner population: a cross-sectional survey. | Health and quality of life outcomes 20090101 |
Effects of genetic deficiency of cyclooxygenase-1 or cyclooxygenase-2 on functional and histological outcomes following traumatic brain injury in mice. | BMC neuroscience 20090101 |
Effect of Genistein on vasculogenic mimicry formation by human uveal melanoma cells. | Journal of experimental & clinical cancer research : CR 20090101 |
Potential prescription patterns and errors in elderly adult patients attending public primary health care centers in Mexico City. | Clinical interventions in aging 20090101 |
Suppressive effect of secretory phospholipase A2 inhibitory peptide on interleukin-1beta-induced matrix metalloproteinase production in rheumatoid synovial fibroblasts, and its antiarthritic activity in hTNFtg mice. | Arthritis research & therapy 20090101 |
Efficacy of antibiotic therapy for SAPHO syndrome is lost after its discontinuation: an interventional study. | Arthritis research & therapy 20090101 |
Suppression of growth, migration and invasion of highly-metastatic human breast cancer cells by berbamine and its molecular mechanisms of action. | Molecular cancer 20090101 |
Drugs associated with more suicidal ideations are also associated with more suicide attempts. | PloS one 20090101 |
Chemopreventive effect of nonsteroidal anti-inflammatory drugs on 9,10-dimethylbenz[a]anthracene-induced lung carcinogenesis in mice. | Oncology research 20090101 |
Tumor-shed PGE(2) impairs IL2Rgammac-signaling to inhibit CD4 T cell survival: regulation by theaflavins. | PloS one 20090101 |
Bradykinin receptor antagonists and cyclooxygenase inhibitors in vincristine- and streptozotocin-induced hyperalgesia. | Pharmacological reports : PR 20090101 |
Role of lipoxygenases and the lipoxin A(4)/annexin 1 receptor in ischemia-reperfusion-induced gastric mucosal damage in rats. | Pharmacology 20090101 |
Familial adenomatous polyposis. | Orphanet journal of rare diseases 20090101 |
Evaluation of Mangosteen juice blend on biomarkers of inflammation in obese subjects: a pilot, dose finding study. | Nutrition journal 20090101 |
Role of lipoxygenases and lipoxin A(4)/annexin-1 receptor in gastric protection induced by 20% ethanol or sodium salicylate in rats. | Pharmacology 20090101 |
Memantine: a review of studies into its safety and efficacy in treating Alzheimer's disease and other dementias. | Clinical interventions in aging 20090101 |
Guaifenesin enhances the analgesic potency of ibuprofen, nimesulide and celecoxib in mice. | Neuro endocrinology letters 20090101 |
Microstructure and mineral composition of dystrophic calcification associated with the idiopathic inflammatory myopathies. | Arthritis research & therapy 20090101 |
Study of the expression of CD30 in pterygia compared to healthy conjunctivas. | Molecular vision 20090101 |
Insulin-like growth factor binding protein-3 has dual effects on gastrointestinal stromal tumor cell viability and sensitivity to the anti-tumor effects of imatinib mesylate in vitro. | Molecular cancer 20090101 |
Efficacy of epicutaneous Diractin (ketoprofen in Transfersome gel) for the treatment of pain related to eccentric muscle contractions. | Drug design, development and therapy 20090101 |
Cyclooxygenase-2 mediated regulation of E-cadherin occurs in conventional but not early-onset gastric cancer cell lines. | Cellular oncology : the official journal of the International Society for Cellular Oncology 20090101 |
Celecoxib in arthritis: relative risk management profile and implications for patients. | Therapeutics and clinical risk management 20090101 |
Prediction of pharmacological and xenobiotic responses to drugs based on time course gene expression profiles. | PloS one 20090101 |
Efficacy of plasma vascular endothelial growth factor in monitoring first-line chemotherapy in patients with advanced non-small cell lung cancer. | BMC cancer 20090101 |
Drug-induced hematologic syndromes. | Advances in hematology 20090101 |
Current and emerging treatments for amyotrophic lateral sclerosis. | Neuropsychiatric disease and treatment 20090101 |
Eradication of intracellular Francisella tularensis in THP-1 human macrophages with a novel autophagy inducing agent. | Journal of biomedical science 20090101 |
Phytalgic, a food supplement, vs placebo in patients with osteoarthritis of the knee or hip: a randomised double-blind placebo-controlled clinical trial. | Arthritis research & therapy 20090101 |
Association of KCNB1 to rheumatoid arthritis via interaction with HLA-DRB1. | BMC proceedings 20090101 |
[Effect of sutent and celecoxib on the properties of endothelial cells in vitro]. | Voprosy onkologii 20090101 |
MMP9 but Not EGFR, MET, ERCC1, P16, and P-53 Is Associated with Response to Concomitant Radiotherapy, Cetuximab, and Weekly Cisplatin in Patients with Locally Advanced Head and Neck Cancer. | Journal of oncology 20090101 |
Safety, tolerability and biological effects of long-term metronomic administration of non-cytotoxic anti-angiogenic agents. | Oncology 20090101 |
Myeloperoxidase content is a marker of systemic inflammation in a chronic condition: the example given by the periodontal disease in rats. | Mediators of inflammation 20090101 |
The effectiveness of a weak opioid medication versus a cyclo-oxygenase-2 (COX-2) selective non-steroidal anti-inflammatory drug in treating flare-up of chronic low-back pain: results from two randomized, double-blind, 6-week studies. | The Journal of international medical research 20090101 |
Efficacy and safety of celecoxib in the treatment of acute pain due to ankle sprain in a Latin American and Middle Eastern population. | The Journal of international medical research 20090101 |
Development and evaluation of transdermal patches of celecoxib. | PDA journal of pharmaceutical science and technology 20090101 |
IL-1beta suppresses the formation of osteoclasts by increasing OPG production via an autocrine mechanism involving celecoxib-related prostaglandins in chondrocytes. | Mediators of inflammation 20090101 |
Na(+)-stimulated Na+/H+ exchange and an unfavorable Ca2+ homeostasis initiate the cycloxygenase-2 inhibitors-induced apoptotic signals in colonic epithelial cells during the early stage of colon carcinogenesis. | Oncology research 20090101 |
Joint assessment of intended and unintended effects of medications: an example using vascular endothelial growth factor inhibitors for neovascular age-related macular degeneration. | Journal of ophthalmology 20090101 |
Role of neo-adjuvant hormonal therapy in the treatment of breast cancer: a review of clinical trials. | International journal of general medicine 20090101 |
Stabilization of quinapril by incorporating hydrogen bonding interactions. | Indian journal of pharmaceutical sciences 20090101 |
Neurobiology of inflammation-associated anorexia. | Frontiers in neuroscience 20090101 |
Targeted therapies in the management of colorectal carcinoma: role of bevacizumab. | OncoTargets and therapy 20090101 |
Current status of treatment of metastatic colorectal cancer with special reference to cetuximab and elderly patients. | OncoTargets and therapy 20090101 |
Targeted therapy in the treatment of malignant gliomas. | OncoTargets and therapy 20090101 |
Management of Barrett's oesophagus. | F1000 medicine reports 20090101 |
Recent advances in peptic ulcer bleeding. | F1000 medicine reports 20090101 |
Effects of celecoxib and ly117018 combination on human breast cancer cells in vitro. | Breast cancer : basic and clinical research 20090101 |
Enhanced dissolution rate of felodipine using spherical agglomeration with Inutec SP1 by quasi emulsion solvent diffusion method. | Research in pharmaceutical sciences 20090101 |
Developments in treating metastatic colorectal cancer: Recent international reports from ASCO 2007 and 2008. | Clinical and experimental gastroenterology 20090101 |
Prevention of NSAID-related upper gastrointestinal toxicity: a meta-analysis of traditional NSAIDs with gastroprotection and COX-2 inhibitors. | Drug, healthcare and patient safety 20090101 |
Phase II study of 'high-dose' celecoxib and metronomic 'low-dose' cyclophosphamide and methotrexate in patients with relapsed and refractory lymphoma. | Ecancermedicalscience 20090101 |
Role of traditional and new biomarkers in breast carcinogenesis. | Ecancermedicalscience 20090101 |
Stability of celecoxib oral suspension. | The Canadian journal of hospital pharmacy 20090101 |
Celecoxib-induced degradation of T-cell factors-1 and -4 in human colon cancer cells. | Biochemical and biophysical research communications 20081226 |
Pirinixic acid derivatives as novel dual inhibitors of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase. | Journal of medicinal chemistry 20081225 |
Enhanced surface attachment of protein-type targeting ligands to poly(lactide-co-glycolide) nanoparticles using variable expression of polymeric acid functionality. | Journal of biomedical materials research. Part A 20081215 |
OSU03012 activates Erk1/2 and Cdks leading to the accumulation of cells in the S-phase and apoptosis. | International journal of cancer 20081215 |
Sensitivity to the non-COX inhibiting celecoxib derivative, OSU03012, is p21(WAF1/CIP1) dependent. | International journal of cancer 20081215 |
2,3,5-Substituted tetrahydrofurans: COX-2 inhibitory activities of 5-hydroxymethyl-/carboxyl-2,3-diaryl-tetrahydro-furan-3-ols. | European journal of medicinal chemistry 20081201 |
Pancreatic cancer: from molecular signature to target therapy. | Critical reviews in oncology/hematology 20081201 |
Long-term NSAID treatment directly decreases COX-2 and mPGES-1 production in the articular cartilage of patients with osteoarthritis. | Osteoarthritis and cartilage 20081201 |
NFAT regulates induction of COX-2 and apoptosis of keratinocytes in response to ultraviolet radiation exposure. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20081201 |
Effects of a selective cyclooxygenase-2 inhibitor on endometrial epithelial cells from patients with endometriosis. | Human reproduction (Oxford, England) 20081201 |
The risk of acute myocardial infarction with etodolac is not increased compared to naproxen: a historical cohort analysis of a generic COX-2 selective inhibitor. | Journal of cardiovascular pharmacology and therapeutics 20081201 |
Induction of multidrug resistance proteins in lymphocytes from patients with arthritic disorders. | Clinical and experimental medicine 20081201 |
Inflammatory mediators involved in the nociceptive and oedematogenic responses induced by Tityus serrulatus scorpion venom injected into rat paws. | Toxicon : official journal of the International Society on Toxinology 20081201 |
Selective COX-2 inhibitors modulate cellular senescence in human dermal fibroblasts in a catalytic activity-independent manner. | Mechanisms of ageing and development 20081201 |
Synthesis of celecoxib analogs that possess a N-hydroxypyrid-2(1H)one 5-lipoxygenase pharmacophore: biological evaluation as dual inhibitors of cyclooxygenases and 5-lipoxygenase with anti-inflammatory activity. | Bioorganic & medicinal chemistry letters 20081201 |
Small-molecule inhibitors of PDK1. | ChemMedChem 20081201 |
Celecoxib nanoemulsion: skin permeation mechanism and bioavailability assessment. | Journal of drug targeting 20081201 |
Postdischarge complications and rehabilitation after ambulatory surgery. | Current opinion in anaesthesiology 20081201 |
Prioritizing future research on off-label prescribing: results of a quantitative evaluation. | Pharmacotherapy 20081201 |
Nonselective and cyclooxygenase-2-selective NSAIDs and acute kidney injury. | The American journal of medicine 20081201 |
Cognitive and cerebral metabolic effects of celecoxib versus placebo in people with age-related memory loss: randomized controlled study. | The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 20081201 |
Nifedipine enhances the relaxant effects of cyclo-oxygenase inhibitors on the bovine ciliary muscle. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20081201 |
Glutathione Peroxidase 2 Inhibits Cyclooxygenase-2-Mediated Migration and Invasion of HT-29 Adenocarcinoma Cells but Supports Their Growth as Tumors in Nude Mice. | Cancer research 20081201 |
Phase II study of celecoxib and docetaxel in non-small cell lung cancer (NSCLC) patients with progression after platinum-based therapy. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20081201 |
A phase I study of gefitinib, capecitabine, and celecoxib in patients with advanced solid tumors. | Molecular cancer therapeutics 20081201 |
Cyclooxygenase inhibitors: instrumental drugs to understand cardiovascular homeostasis and arterial thrombosis. | Cardiovascular & hematological disorders drug targets 20081201 |
Low-level laser therapy improves bone repair in rats treated with anti-inflammatory drugs. | Journal of oral rehabilitation 20081201 |
Combination of an EGFR blocker and a COX-2 inhibitor for the treatment of advanced cutaneous squamous cell carcinoma. | Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 20081201 |
[Effect of a selective COX-2 inhibitor on cell proliferation and apoptosis in human gastric cancer cell line BGC-823]. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20081201 |
[COX-2 or nNOS mediates cardioprotection during the final stage of the late phase of ischemic preconditioning]. | Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20081201 |
Comparison of the effectiveness and tolerability of lidocaine patch 5% versus celecoxib for osteoarthritis-related knee pain: post hoc analysis of a 12 week, prospective, randomized, active-controlled, open-label, parallel-group trial in adults. | Clinical therapeutics 20081201 |
Effect of celecoxib on anticonvulsant activity of carbamazepine against maximal electroshock-induced convulsions in mice. | Methods and findings in experimental and clinical pharmacology 20081201 |
Systems biology: a therapeutic target for tumor therapy. | Cancer microenvironment : official journal of the International Cancer Microenvironment Society 20081201 |
Current migraine management - patient acceptability and future approaches. | Neuropsychiatric disease and treatment 20081201 |
Renin inhibition with aliskiren in hypertension: focus on aliskiren/hydrochlorothiazide combination therapy. | Vascular health and risk management 20081201 |
Topical nepafenac in the treatment of diabetic macular edema. | Clinical ophthalmology (Auckland, N.Z.) 20081201 |
The target of arachidonic acid pathway is a new anticancer strategy for human prostate cancer. | Biologics : targets & therapy 20081201 |
First-line therapeutic strategies in metastatic colorectal cancer. | Oncology (Williston Park, N.Y.) 20081130 |
Co-localization of glucocorticoid metabolizing and prostaglandin synthesizing enzymes in rat kidney and liver. | Life sciences 20081121 |
Differential involvement of cyclooxygenase isoforms in neutrophil migration in vivo and in vitro. | European journal of pharmacology 20081119 |
Changing perceptions and practices regarding aspirin, nonsteroidal anti-inflammatory drugs, and cyclooxygenase-2 selective nonsteroidal anti-inflammatory drugs among US primary care providers. | Alimentary pharmacology & therapeutics 20081115 |
Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 5-(4-hydroxymethylphenyl)-1-(4-aminosulfonylphenyl)-3-trifluoromethyl-1H-pyrazole and its methanesulfonyl analog: synthesis, biological evaluation and nitric oxide release studies. | Bioorganic & medicinal chemistry 20081115 |
OSU-03012, a novel celecoxib derivative, induces reactive oxygen species-related autophagy in hepatocellular carcinoma. | Cancer research 20081115 |
Responder analysis and correlation of outcome measures: pooled results from two identical studies comparing etoricoxib, celecoxib, and placebo in osteoarthritis. | Osteoarthritis and cartilage 20081101 |
Intraperitoneal inflammation decreases endometriosis in a mouse model. | Human reproduction (Oxford, England) 20081101 |
COX-1, and not COX-2 activity, regulates airway function: relevance to aspirin-sensitive asthma. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20081101 |
Non-steroidal anti-inflammatory drugs and cardiac failure: meta-analyses of observational studies and randomised controlled trials. | European journal of heart failure 20081101 |
Altered gene expression profiles define pathways in colorectal cancer cell lines affected by celecoxib. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20081101 |
Phase II study of docetaxel and celecoxib, a cyclooxygenase-2 inhibitor, in elderly or poor performance status (PS2) patients with advanced non-small cell lung cancer. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20081101 |
Cyclooxygenase-2 inhibitor inhibits hippocampal synaptic reorganization in pilocarpine-induced status epilepticus rats. | Journal of Zhejiang University. Science. B 20081101 |
Selective COX2 inhibition improves whole body and muscular insulin resistance in fructose-fed rats. | European journal of clinical investigation 20081101 |
Importance of Bak for celecoxib-induced apoptosis. | Biochemical pharmacology 20081030 |
Celecoxib induces p53-PUMA pathway for apoptosis in human colorectal cancer cells. | Chemico-biological interactions 20081022 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1. | Journal of medicinal chemistry 20081009 |
Insights into inflammation and influenza. | The New England journal of medicine 20081009 |
Single dose oral celecoxib for acute postoperative pain in adults. | The Cochrane database of systematic reviews 20081008 |
Cytokine-induced neutrophil chemoattractant (CINC)-1 induces fever by a prostaglandin-dependent mechanism in rats. | Brain research 20081003 |
Celecoxib inhibits growth of tumors in a syngeneic rat liver metastases model for colorectal cancer. | Cancer chemotherapy and pharmacology 20081001 |
Celecoxib inhibits 5-lipoxygenase. | Biochemical pharmacology 20081001 |
Celecoxib for treatment of nocturia caused by benign prostatic hyperplasia: a prospective, randomized, double-blind, placebo-controlled study. | Urology 20081001 |
Hospitalization for peptic ulcer and bleeding in users of selective COX-2 inhibitors and nonselective NSAIDs with special reference to celecoxib. | Pharmacoepidemiology and drug safety 20081001 |
STAMPEDE: Systemic Therapy for Advancing or Metastatic Prostate Cancer--a multi-arm multi-stage randomised controlled trial. | Clinical oncology (Royal College of Radiologists (Great Britain)) 20081001 |
Dopaminergic but not glutamatergic neurotransmission is increased in the striatum after selective cyclooxygenase-2 inhibition in normal and hemiparkinsonian rats. | Basic & clinical pharmacology & toxicology 20081001 |
In-vivo effects and mechanisms of celecoxib-reduced growth of cyclooxygenase-2 (COX-2)-expressing versus COX-2-deleted human HCC xenografts in nude mice. | Anti-cancer drugs 20081001 |
Chemoprevention and Barrett's esophagus: decisions, decisions. | The American journal of gastroenterology 20081001 |
Patient preferences for the chemoprevention of esophageal adenocarcinoma in Barrett's esophagus. | The American journal of gastroenterology 20081001 |
Synthesis of new 4-[2-(4-methyl(amino)sulfonylphenyl)-5-trifluoromethyl-2H-pyrazol-3-yl]-1,2,3,6-tetrahydropyridines: a search for novel nitric oxide donor anti-inflammatory agents. | Bioorganic & medicinal chemistry 20081001 |
Prostaglandin E2 exerts catabolic effects in osteoarthritis cartilage: evidence for signaling via the EP4 receptor. | Journal of immunology (Baltimore, Md. : 1950) 20081001 |
Effect of celecoxib and the novel anti-cancer agent, dimethylamino-parthenolide, in a developmental model of pancreatic cancer. | Pancreas 20081001 |
The effect of glucosamine and/or chondroitin sulfate on the progression of knee osteoarthritis: a report from the glucosamine/chondroitin arthritis intervention trial. | Arthritis and rheumatism 20081001 |
The effects of selective COX-2 inhibitor/celecoxib and omega-3 fatty acid on matrix metalloproteinases, TIMP-1, and laminin-5gamma2-chain immunolocalization in experimental periodontitis. | Journal of periodontology 20081001 |
A pilot surrogate endpoint biomarker study of celecoxib in oral premalignant lesions. | Cancer prevention research (Philadelphia, Pa.) 20081001 |
The renin angiotensin system in the development of cardiovascular disease: role of aliskiren in risk reduction. | Vascular health and risk management 20081001 |
Intrathecal corticosteroids might slow Alzheimer's disease progression. | Neuropsychiatric disease and treatment 20081001 |
Risk management profile of etoricoxib: an example of personalized medicine. | Therapeutics and clinical risk management 20081001 |
[Postoperative analgesia after laparoscopic cholecystectomy: comparison of the preoperative administration of celecoxib with paracetamol?]. | La Tunisie medicale 20081001 |
Neuropharmacology. | Indian journal of pharmacology 20081001 |
Synergistic anti-hyperalgesia of electroacupuncture and low dose of celecoxib in monoarthritic rats: involvement of the cyclooxygenase activity in the spinal cord. | Brain research bulletin 20080930 |
Electrochemical detection of celecoxib at a polyaniline grafted multiwall carbon nanotubes modified electrode. | Analytica chimica acta 20080919 |
Review: celecoxib increases risk for cardiovascular events; risks are greatest with higher doses. | ACP journal club 20080916 |
Ibuprofen administration attenuates serum TNF-alpha levels, hepatic glutathione depletion, hepatic apoptosis and mouse mortality after Fas stimulation. | Toxicology and applied pharmacology 20080915 |
Characterization of eltenac and novel COX-2 selective thiopheneacetic acid analogues in vitro and in vivo. | Biochemical pharmacology 20080915 |
TRAIL-mediated apoptosis in malignant glioma cells is augmented by celecoxib through proteasomal degradation of survivin. | Neuroscience letters 20080912 |
Speeding up the evaluation of new agents in cancer. | Journal of the National Cancer Institute 20080903 |
Molecular pathways involved in the synergistic interaction of the PKC beta inhibitor enzastaurin with the antifolate pemetrexed in non-small cell lung cancer cells. | British journal of cancer 20080902 |
Impact of celecoxib on capecitabine tolerability and activity in pretreated metastatic breast cancer: results of a phase II study with biomarker evaluation. | Cancer chemotherapy and pharmacology 20080901 |
Celecoxib has potent antitumour effects as a single agent and in combination with BCG immunotherapy in a model of urothelial cell carcinoma. | European urology 20080901 |
Editorial comment on: celecoxib has potent antitumour effects as a single agent and in combination with BCG immunotherapy in a model of urothelial cell carcinoma. | European urology 20080901 |
Effects of short- and long-term celecoxib on orthodontic tooth movement. | The Angle orthodontist 20080901 |
The use of medication and nutritional supplements during FIFA World Cups 2002 and 2006. | British journal of sports medicine 20080901 |
Celecoxib but not the combination of celecoxib+atorvastatin prevents the development of monocrotaline-induced pulmonary hypertension in the rat. | Naunyn-Schmiedeberg's archives of pharmacology 20080901 |
Combination regimen with statins and NSAIDs: a promising strategy for cancer chemoprevention. | International journal of cancer 20080901 |
Cyclooxygenase 2-selective and nonselective nonsteroidal anti-inflammatory drugs induce oxidative stress by up-regulating vascular NADPH oxidases. | The Journal of pharmacology and experimental therapeutics 20080901 |
Cyclooxygenase inhibitors down regulate P-glycoprotein in human colorectal Caco-2 cell line. | Pharmaceutical research 20080901 |
Cancer is a preventable disease that requires major lifestyle changes. | Pharmaceutical research 20080901 |
Celecoxib potently inhibits TNFalpha-induced nuclear translocation and activation of NF-kappaB. | Biochemical pharmacology 20080901 |
CTLA-4 blockade with ipilimumab induces significant clinical benefit in a female with melanoma metastases to the CNS. | Nature clinical practice. Oncology 20080901 |
Novel chemotherapy approaches in chemoradiation protocols. | Gynecologic oncology 20080901 |
Adaptation of Bayesian data mining algorithms to longitudinal claims data: coxib safety as an example. | Medical care 20080901 |
Synthesis, in vitro, and in vivo biological evaluation and molecular docking simulations of chiral alcohol and ether derivatives of the 1,5-diarylpyrrole scaffold as novel anti-inflammatory and analgesic agents. | Bioorganic & medicinal chemistry 20080901 |
Celecoxib for lupus. | Arthritis and rheumatism 20080901 |
Anti-inflammatory drugs fall short in Alzheimer's disease. | Nature medicine 20080901 |
A ligand-based approach to mining the chemogenomic space of drugs. | Combinatorial chemistry & high throughput screening 20080901 |
[Controlled clinical trials on the effects of Chinese traditional medicine for the treatment of osteoarthritis of knee joint at early stage and its MRI changes]. | Zhongguo gu shang = China journal of orthopaedics and traumatology 20080901 |
Celecoxib, NSAIDs and the skeleton. | Drugs of today (Barcelona, Spain : 1998) 20080901 |
Synthesis, biological evaluation, and enzyme docking simulations of 1,5-diarylpyrrole-3-alkoxyethyl ethers as selective cyclooxygenase-2 inhibitors endowed with anti-inflammatory and antinociceptive activity. | Journal of medicinal chemistry 20080814 |
Possible glutamatergic and lipid signalling mechanisms in ECT-induced retrograde amnesia: experimental evidence for involvement of COX-2, and review of literature. | Journal of psychiatric research 20080801 |
Effects of selective vs. nonselective cyclooxygenase inhibition on dynamic renal potassium excretion: a randomized trial. | Clinical pharmacology and therapeutics 20080801 |
The pattern of use of non-steroidal anti-inflammatory drugs (NSAIDs) from 1997 to 2005: a nationwide study on 4.6 million people. | Pharmacoepidemiology and drug safety 20080801 |
Atorvastatin and celecoxib: a future role in cancer chemoprevention. | International journal of cancer 20080801 |
Was the thrombotic risk of rofecoxib predictable from the French Pharmacovigilance Database before 30 September 2004? | European journal of clinical pharmacology 20080801 |
Short-term administration of non-selective and selective COX-2 NSAIDs do not interfere with bone repair in rats. | Journal of molecular histology 20080801 |
Can drug removals involving cyclooxygenase-2 inhibitors be avoided? A plea for human pharmacology. | Trends in pharmacological sciences 20080801 |
A novel, efficient, randomized selection trial comparing combinations of drug therapy for ALS. | Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20080801 |
Improvement of thyroid eye disease following treatment with the cyclooxygenase-2 selective inhibitor celecoxib. | Thyroid : official journal of the American Thyroid Association 20080801 |
Celecoxib pre-treatment in human colorectal adenocarcinoma patients is associated with gene expression alterations suggestive of diminished cellular proliferation. | European journal of cancer (Oxford, England : 1990) 20080801 |
[Analgesic effects of electroacupuncture combined with Celebrex on rats with tibial cancer pain]. | Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine 20080801 |
Progressive metaplastic and dysplastic changes in mouse pancreas induced by cyclooxygenase-2 overexpression. | Neoplasia (New York, N.Y.) 20080801 |
Suppression of tumor formation by a cyclooxygenase-2 inhibitor and a peroxisome proliferator-activated receptor gamma agonist in an in vivo mouse model of spontaneous breast cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080801 |
Celecoxib upregulates multidrug resistance proteins in colon cancer: lack of synergy with standard chemotherapy. | Current cancer drug targets 20080801 |
Cyclooxygenase-2 inhibitors in colorectal cancer prevention: point. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080801 |
Histological analysis of orthodontic root resorption in rats treated with the cyclooxygenase-2 (COX-2) inhibitor celecoxib. | Orthodontics & craniofacial research 20080801 |
The combined effects of celecoxib and minocycline hydrochloride on inhibiting the osseous metastasis of breast cancer in nude mice. | Cancer biotherapy & radiopharmaceuticals 20080801 |
Cardiovascular and gastrointestinal toxicity of selective cyclo-oxygenase-2 inhibitors in man. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20080801 |
In vitro inhibition of CYP1A2 by model inhibitors, anti-inflammatory analgesics and female sex steroids: predictability of in vivo interactions. | Basic & clinical pharmacology & toxicology 20080801 |
[Xiaojin Wan inhibits the expression of COX-2 in prostate tissues of prostatitis pain rats]. | Zhonghua nan ke xue = National journal of andrology 20080801 |
Present and prospective clinical therapeutic regimens for Alzheimer's disease. | Neuropsychiatric disease and treatment 20080801 |
[Efficacy of Lugua polypeptide injection on active rheumatoid arthritis]. | Zhongguo gu shang = China journal of orthopaedics and traumatology 20080801 |
Combination chemoprevention of HER2/neu-induced breast cancer using a cyclooxygenase-2 inhibitor and a retinoid X receptor-selective retinoid. | Cancer prevention research (Philadelphia, Pa.) 20080801 |
Comment re: 'Sporadic aberrant crypt foci are not a surrogate endpoint for colorectal adenoma prevention' and 'Aberrant crypt foci in the adenoma prevention with celecoxib trial'. | Cancer prevention research (Philadelphia, Pa.) 20080801 |
Allosteric modulation of SULT2A1 by celecoxib and nimesulide: computational analyses. | Drug metabolism letters 20080801 |
Celecoxib-related gastroduodenal ulcer and cardiovascular events in a randomized trial for gastric cancer prevention. | World journal of gastroenterology 20080728 |
Effects of celecoxib on ionic currents and spontaneous firing in rat retinal neurons. | Neuroscience 20080717 |
Reduced expression of cyclooxygenase-2 in primary breast cancer. | Journal of the National Cancer Institute 20080716 |
The anti-proliferative potency of celecoxib is not a class effect of coxibs. | Biochemical pharmacology 20080715 |
[American judge preserves confidentiality in the peer review process]. | Nederlands tijdschrift voor geneeskunde 20080712 |
Efficacy and safety of a novel synergistic drug candidate, CRx-102, in hand osteoarthritis. | Annals of the rheumatic diseases 20080701 |
Celecoxib-induced growth inhibition in SW480 colon cancer cells is associated with activation of protein kinase G. | Molecular carcinogenesis 20080701 |
Late-onset celecoxib-induced combined hepato-nephrotoxicity. | British journal of clinical pharmacology 20080701 |
Perioperative use of beta-blockers and COX-2 inhibitors may improve immune competence and reduce the risk of tumor metastasis. | Annals of surgical oncology 20080701 |
A celecoxib derivative inhibits focal adhesion signaling and induces caspase-8-dependent apoptosis in human acute myeloid leukemia cells. | International journal of cancer 20080701 |
Nonaspirin NSAIDs, cyclooxygenase 2 inhibitors, and the risk for stroke. | Stroke 20080701 |
Evidence for the role of neurogenic inflammation components in trypsin-elicited scratching behaviour in mice. | British journal of pharmacology 20080701 |
Cognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT): results of a randomized, controlled trial of naproxen and celecoxib. | Archives of neurology 20080701 |
Dimethylcelecoxib inhibits prostaglandin E2 production. | Biochemical pharmacology 20080701 |
Anticholinergic activity of 107 medications commonly used by older adults. | Journal of the American Geriatrics Society 20080701 |
Diazen-1-ium-1,2-diolated nitric oxide donor ester prodrugs of 1-(4-methanesulfonylphenyl)-5-aryl-1H-pyrazol-3-carboxylic acids: synthesis, nitric oxide release studies and anti-inflammatory activities. | Bioorganic & medicinal chemistry 20080701 |
Celecoxib anti-aromatase neoadjuvant (CAAN) trial for locally advanced breast cancer. | The Journal of steroid biochemistry and molecular biology 20080701 |
Celecoxib as an in vivo probe of cyclooxygenase-2 mechanisms underlying retrograde amnesia in an animal model of ECT. | Journal of neural transmission (Vienna, Austria : 1996) 20080701 |
Involvement of subcellular organelles in inflammatory pain-induced oxidative stress and apoptosis in the rat hepatocytes. | Archives of Iranian medicine 20080701 |
The safety of celecoxib in ankylosing spondylitis treatment. | Expert opinion on drug safety 20080701 |
A new knee surgery model in rats to evaluate functional measures of postoperative pain. | Anesthesia and analgesia 20080701 |
Therapeutic effect of Siegesbeckia pubescens on cartilage protection in a rabbit collagenase-induced model of osteoarthritis. | Journal of pharmacological sciences 20080701 |
Cyclooxygenase inhibitors block uterine tumorigenesis in HMGA1a transgenic mice and human xenografts. | Molecular cancer therapeutics 20080701 |
Metronomic etoposide/cyclophosphamide/celecoxib regimen given to children and adolescents with refractory cancer: a preliminary monocentric study. | Clinical therapeutics 20080701 |
Effects of a cyclooxygenase 2 inhibitor on fracture healing in a rat model. | American journal of orthopedics (Belle Mead, N.J.) 20080701 |
Metastatic hepatic epithelioid hemangioendothelioma in a teenage girl. | Journal of pediatric hematology/oncology 20080701 |
Indole cytosolic phospholipase A2 alpha inhibitors: discovery and in vitro and in vivo characterization of 4-{3-[5-chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic acid, efipladib. | Journal of medicinal chemistry 20080626 |
[A phase II clinical trial of celecoxib combined with platinum-based chemotherapy in the treatment of patients with advanced NSCLC as first-line treatment.]. | Zhongguo fei ai za zhi = Chinese journal of lung cancer 20080620 |
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2). | Journal of medicinal chemistry 20080612 |
Drugs to prevent colon cancer show promise, but hurdles remain for chemoprevention. | Journal of the National Cancer Institute 20080604 |
[Postoperative inconveniences after breast cancer surgery]. | Ugeskrift for laeger 20080602 |
[Multimodal treatment of pain and nausea in breast cancer surgery]. | Ugeskrift for laeger 20080602 |
Exploration of physicochemical properties and molecular modelling studies of 2-sulfonyl-phenyl-3-phenyl-indole analogs as cyclooxygenase-2 inhibitors. | European journal of medicinal chemistry 20080601 |
Celecoxib inhibits production of MMP and NO via down-regulation of NF-kappaB and JNK in a PGE2 independent manner in human articular chondrocytes. | Rheumatology international 20080601 |
Imatinib-resistant K562 cells are more sensitive to celecoxib, a selective COX-2 inhibitor: role of COX-2 and MDR-1. | Leukemia research 20080601 |
Development and validation of a sensitive LC-MS/MS method with electrospray ionization for quantitation of rhein in human plasma: application to a pharmacokinetic study. | Biomedical chromatography : BMC 20080601 |
Validating the effects of drug treatment on blood pressure in the General Practice Research Database. | Pharmacoepidemiology and drug safety 20080601 |
Exploitation of HIV protease inhibitor Indinavir as a memory restorative agent in experimental dementia. | Pharmacology, biochemistry, and behavior 20080601 |
Inhibition of mouse osteoblast proliferation and prostaglandin E2 synthesis by Ulmus davidiana Planch (Ulmaceae). | Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20080601 |
Risk of ischaemic cardiovascular events from selective cyclooxygenase-2 inhibitors in osteoarthritis. | Pharmacoepidemiology and drug safety 20080601 |
Selective COX-2 inhibitors, NSAIDs and congestive heart failure: differences between new and recurrent cases. | British journal of clinical pharmacology 20080601 |
Renal hemodynamic effect of cyclooxygenase 2 inhibition in young men and women with uncomplicated type 1 diabetes mellitus. | American journal of physiology. Renal physiology 20080601 |
Phase II study of temozolomide, thalidomide, and celecoxib for newly diagnosed glioblastoma in adults. | Neuro-oncology 20080601 |
Central ghrelin gastroprotection involves nitric oxide/prostaglandin cross-talk. | British journal of pharmacology 20080601 |
Basic evidence of molecular targeted therapy for oral cancer and salivary gland cancer. | Head & neck 20080601 |
Comparative inhibitory activity of etoricoxib, celecoxib, and diclofenac on COX-2 versus COX-1 in healthy subjects. | Journal of clinical pharmacology 20080601 |
Towards the first inhibitors of trihydroxynaphthalene reductase from Curvularia lunata: synthesis of artificial substrate, homology modelling and initial screening. | Bioorganic & medicinal chemistry 20080601 |
Does celecoxib have pre-emptive analgesic effect after Caesarean section surgery? | British journal of anaesthesia 20080601 |
Current methods for predicting human food effect. | The AAPS journal 20080601 |
Clinical trials update from the American College of Cardiology 2008: CARISMA, TRENDS, meta-analysis of Cox-2 studies, HAT, ON-TARGET, HYVET, ACCOMPLISH, MOMENTUM, PROTECT, HORIZON-HF and REVERSE. | European journal of heart failure 20080601 |
Multimodal analgesia without parenteral narcotics for total knee arthroplasty. | The Journal of arthroplasty 20080601 |
Modulation of the expression of the invasion-suppressor CRMP-1 by cyclooxygenase-2 inhibition via reciprocal regulation of Sp1 and C/EBPalpha. | Molecular cancer therapeutics 20080601 |
Apoptosis-inducing effect of erlotinib is potentiated by 3,3'-diindolylmethane in vitro and in vivo using an orthotopic model of pancreatic cancer. | Molecular cancer therapeutics 20080601 |
Selective inhibition of cyclooxygenase-2 suppresses the growth of pancreatic cancer cells in vitro and in vivo. | The Tohoku journal of experimental medicine 20080601 |
Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) syndrome induced by celecoxib and anti-tuberculosis drugs. | Journal of Korean medical science 20080601 |
Celecoxib: new indication. Ankylosing spondylitis: no pain justifies the use of a cox-2 inhibitor. Patients still exposed to unjustified risks. | Prescrire international 20080601 |
[Effects of a selective cyclooxygenase 2 inhibitor celecoxib on the proliferation and apoptosis of human prostate cancer cell line PC-3]. | Zhonghua nan ke xue = National journal of andrology 20080601 |
Antiatherosclerotic activity of ibuprofen, a non-selective COX inhibitor--an animal study. | Indian journal of experimental biology 20080601 |
Cardiovascular co-morbidity in rheumatic diseases. | Vascular health and risk management 20080601 |
[Celecoxib induces apoptosis and inhibits angiogenesis in gastric cancer]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20080601 |
Aberrant crypt foci in the adenoma prevention with celecoxib trial. | Cancer prevention research (Philadelphia, Pa.) 20080601 |
Musculoskeletal performance and hydration status. | Current reviews in musculoskeletal medicine 20080601 |
Heterogeneous gene expression changes in colorectal cancer cells share the WNT pathway in response to growth suppression by APHS-mediated COX-2 inhibition. | Biologics : targets & therapy 20080601 |
Evaluation of antidepressant activity of tramadol in mice. | Indian journal of pharmacology 20080601 |
Circulating neutrophils maintain physiological blood pressure by suppressing bacteria and IFNgamma-dependent iNOS expression in the vasculature of healthy mice. | Blood 20080515 |
Novel anti-inflammatory agents based on pyridazinone scaffold; design, synthesis and in vivo activity. | Bioorganic & medicinal chemistry 20080515 |
TTX-R Na+ current-reduction by celecoxib correlates with changes in PGE(2) and CGRP within rat DRG neurons during acute incisional pain. | Brain research 20080513 |
Advanced small cell carcinoma of the ovary in a seventeen-year-old female, successfully treated with surgery and multi-agent chemotherapy. | Pediatric blood & cancer 20080501 |
Arachidonic acid pathway activates multidrug resistance related protein in cultured human lung cells. | Archives of toxicology 20080501 |
The select cyclooxygenase-2 inhibitor celecoxib reduced the extent of atherosclerosis in apo E-/- mice. | The Journal of surgical research 20080501 |
Pharmaceutical particle engineering via spray drying. | Pharmaceutical research 20080501 |
Irinotecan combined with infusional 5-fluorouracil/folinic acid or capecitabine plus celecoxib or placebo in the first-line treatment of patients with metastatic colorectal cancer. EORTC study 40015. | Annals of oncology : official journal of the European Society for Medical Oncology 20080501 |
Celecoxib, a cyclooxygenase-2 inhibitor, induces apoptosis in human osteosarcoma cell line MG-63 via down-regulation of PI3K/Akt. | Cell biology international 20080501 |
Seizure-induced up-regulation of P-glycoprotein at the blood-brain barrier through glutamate and cyclooxygenase-2 signaling. | Molecular pharmacology 20080501 |
Combination of atorvastatin and celecoxib synergistically induces cell cycle arrest and apoptosis in colon cancer cells. | International journal of cancer 20080501 |
Celecoxib is a CYP1A2 inhibitor in vitro but not in vivo. | European journal of clinical pharmacology 20080501 |
Predictors of orphan drug approval in the European Union. | European journal of clinical pharmacology 20080501 |
Changes in gene expression induced by chemoradiation in advanced cervical carcinoma: a microarray study of RTOG C-0128. | Gynecologic oncology 20080501 |
Evaluating drug toxicity signals: is a hierarchical classification of evidence useful or a hindrance? | Pharmacoepidemiology and drug safety 20080501 |
Safety, efficacy and anti-inflammatory activity of rho iso-alpha-acids from hops. | Phytochemistry 20080501 |
Diacerein has a weak effect on the catabolic pathway of human osteoarthritis synovial fibroblast--comparison to its effects on osteoarthritic chondrocytes. | Rheumatology (Oxford, England) 20080501 |
Exploring the mechanisms behind S-adenosylmethionine (SAMe) in the treatment of osteoarthritis. | Critical reviews in food science and nutrition 20080501 |
Can celecoxib affect P-glycoprotein-mediated drug efflux? A microPET study. | Nuclear medicine and biology 20080501 |
By the way, doctor. Celebrex and bleeding. | Harvard health letter 20080501 |
Celecoxib and ankylosing spondylitis. | Expert review of clinical immunology 20080501 |
Preserving confidentiality in the peer review process. | JAMA 20080423 |
Phellinus linteus suppresses growth, angiogenesis and invasive behaviour of breast cancer cells through the inhibition of AKT signalling. | British journal of cancer 20080422 |
A pharmacokinetic and pharmacodynamic study on metronomic irinotecan in metastatic colorectal cancer patients. | British journal of cancer 20080422 |
Cardiovascular risk of celecoxib in 6 randomized placebo-controlled trials: the cross trial safety analysis. | Circulation 20080422 |
Posttranscriptional regulation of the telomerase hTERT by gambogic acid in human gastric carcinoma 823 cells. | Cancer letters 20080418 |
Celecoxib and a novel COX-2 inhibitor ON09310 upregulate death receptor 5 expression via GADD153/CHOP. | Oncogene 20080417 |
Development of a rapidly dispersing tablet of a poorly wettable compound: formulation DOE and mechanistic study of effect of formulation excipients on wetting of celecoxib. | International journal of pharmaceutics 20080402 |
GSK-3beta regulates cyclin D1 expression: a new target for chemotherapy. | Cellular signalling 20080401 |
Modulation of dopaminergic neurotransmission in rat striatum upon in vitro and in vivo diclofenac treatment. | Journal of neurochemistry 20080401 |
OSU-03012 stimulates PKR-like endoplasmic reticulum-dependent increases in 70-kDa heat shock protein expression, attenuating its lethal actions in transformed cells. | Molecular pharmacology 20080401 |
[Changes in quality of life in patients with osteoarthritis treated with celecoxib: the Qualice study]. | Presse medicale (Paris, France : 1983) 20080401 |
Cardiac remodelling hinders activation of cyclooxygenase-2, diminishing protection by delayed pharmacological preconditioning: role of HIF1 alpha and CREB. | Cardiovascular research 20080401 |
Design, synthesis, and biological evaluation of 1-(4-sulfamylphenyl)-3-trifluoromethyl-5-indolyl pyrazolines as cyclooxygenase-2 (COX-2) and lipoxygenase (LOX) inhibitors. | Bioorganic & medicinal chemistry 20080401 |
Effect of phenytoin on celecoxib pharmacokinetics in patients with glioblastoma. | Neuro-oncology 20080401 |
The relative efficacies of gastroprotective strategies in chronic users of nonsteroidal anti-inflammatory drugs. | Gastroenterology 20080401 |
Celecoxib modulates hypertrophic signalling and prevents load-induced cardiac dysfunction. | European journal of heart failure 20080401 |
Pharmacological treatment of heterotopic ossification following hip and acetabular surgery. | Expert opinion on pharmacotherapy 20080401 |
A prospective randomized trial on the role of perioperative celecoxib administration for total knee arthroplasty: improving clinical outcomes. | Anesthesia and analgesia 20080401 |
Stimulating catheters for continuous femoral nerve blockade after total knee arthroplasty: a randomized, controlled, double-blinded trial. | Anesthesia and analgesia 20080401 |
The antiplatelet effect of six non-steroidal anti-inflammatory drugs and their pharmacodynamic interaction with aspirin in healthy volunteers. | The American journal of cardiology 20080401 |
Celecoxib and hypertension-insights from the effect of celecoxib on restenosis after coronary angioplasty with a taxus stent trial. | The American journal of cardiology 20080401 |
Gefitinib plus celecoxib in chemotherapy-naïve patients with stage IIIB/IV non-small cell lung cancer: a phase II study from the Hoosier Oncology Group. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080401 |
The potential predictive value of cyclooxygenase-2 expression and increased risk of gastrointestinal hemorrhage in advanced non-small cell lung cancer patients treated with erlotinib and celecoxib. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080401 |
Pilot randomized phase II study of celecoxib in oral premalignant lesions. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080401 |
Gemcitabine plus celecoxib in patients with advanced or metastatic pancreatic adenocarcinoma: results of a phase II trial. | American journal of clinical oncology 20080401 |
Chemoprevention of colorectal neoplasia: the potential for personalized medicine. | Gastroenterology 20080401 |
Cyclooxygenase-2 selective non-steroidal anti-inflammatory drugs (etodolac, meloxicam, celecoxib, rofecoxib, etoricoxib, valdecoxib and lumiracoxib) for osteoarthritis and rheumatoid arthritis: a systematic review and economic evaluation. | Health technology assessment (Winchester, England) 20080401 |
Cyclooxygenase-2 dependent and independent antitumor effects induced by celecoxib in urinary bladder cancer cells. | Molecular cancer therapeutics 20080401 |
[Mechanism of exacerbation of colonic damage in experimental colitis treated with celecoxib]. | Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences 20080401 |
Applying blood-brain barrier in vitro models to study the influence of drugs on endothelial cells--effects of selected COX-inhibitors. | Die Pharmazie 20080401 |
Review of the cardiovascular safety of COXIBs compared to NSAIDS. | Cardiovascular journal of Africa 20080401 |
Celecoxib: still around, unfortunately. | Prescrire international 20080401 |
[Tolerance to celecoxib and meloxicam in patients with intolerance to nonsteroidal anti-inflammatory drugs]. | Anales de medicina interna (Madrid, Spain : 1984) 20080401 |
Efficacy and tolerability of lumiracoxib, a highly selective cyclo-oxygenase-2 (COX2) inhibitor, in the management of pain and osteoarthritis. | Therapeutics and clinical risk management 20080401 |
Altered GABAergic neurotransmission is associated with increased kainate-induced seizure in prostaglandin-endoperoxide synthase-2 deficient mice. | Brain research bulletin 20080328 |
CS-706, a novel cyclooxygenase-2 selective inhibitor, prolonged the survival of tumor-bearing mice when treated alone or in combination with anti-tumor chemotherapeutic agents. | International journal of cancer 20080315 |
Diazen-1-ium-1,2-diolated and nitrooxyethyl nitric oxide donor ester prodrugs of anti-inflammatory (E)-2-(aryl)-3-(4-methanesulfonylphenyl)acrylic acids: synthesis, cyclooxygenase inhibition, and nitric oxide release studies. | Bioorganic & medicinal chemistry 20080315 |
Cytotoxicity and proteomics analyses of OSU03013 in lung cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20080315 |
Treatment of advanced hormone-sensitive breast cancer in postmenopausal women with exemestane alone or in combination with celecoxib. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080310 |
Crunch time for peer review in lawsuit. | Nature 20080306 |
Synthesis and biological evaluation of some thiazolyl and thiadiazolyl derivatives of 1H-pyrazole as anti-inflammatory antimicrobial agents. | European journal of medicinal chemistry 20080301 |
Comparison of two different dosages of celecoxib with diclofenac for the treatment of active ankylosing spondylitis: results of a 12-week randomised, double-blind, controlled study. | Annals of the rheumatic diseases 20080301 |
Endoscopic ulcer rates in healthy subjects associated with use of aspirin (81 mg q.d.) alone or coadministered with celecoxib or naproxen: a randomized, 1-week trial. | Digestive diseases and sciences 20080301 |
Cyclooxygenase-2 mediates the delayed cardioprotection induced by hydrogen sulfide preconditioning in isolated rat cardiomyocytes. | Pflugers Archiv : European journal of physiology 20080301 |
Pro-inflammatory effect in mice of CvL, a lectin from the marine sponge Cliona varians. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20080301 |
Prevention of upper aerodigestive tract cancer in zinc-deficient rodents: inefficacy of genetic or pharmacological disruption of COX-2. | International journal of cancer 20080301 |
Clinical use and pharmacological properties of selective COX-2 inhibitors. | European journal of clinical pharmacology 20080301 |
The effects of COX-1 and COX-2 inhibitors on prostaglandin synthesis and the formation of heterotopic bone in a rat model. | Archives of orthopaedic and trauma surgery 20080301 |
Selective COX-2 inhibitors. Part 2: synthesis and biological evaluation of 4-benzylideneamino- and 4-phenyliminomethyl-benzenesulfonamides. | Bioorganic & medicinal chemistry 20080301 |
A COX-2 inhibitor combined with chemoradiation of locally advanced rectal cancer: a phase II trial. | International journal of colorectal disease 20080301 |
The effect of cyclooxygenase-2 inhibition on renal hemodynamic function in humans with type 1 diabetes. | Diabetes 20080301 |
Celecoxib modulates adhesion of HT29 colon cancer cells to vascular endothelial cells by inhibiting ICAM-1 and VCAM-1 expression. | British journal of pharmacology 20080301 |
Celecoxib decreases expression of the adhesion molecules ICAM-1 and VCAM-1 in a colon cancer cell line (HT29). | British journal of pharmacology 20080301 |
The effects of cyclooxygenase-2 expression in prostate cancer cells: modulation of response to cytotoxic agents. | The Journal of pharmacology and experimental therapeutics 20080301 |
Celecoxib as an adjunct in the treatment of depressive or mixed episodes of bipolar disorder: a double-blind, randomized, placebo-controlled study. | Human psychopharmacology 20080301 |
Endothelin-1 increases expression of cyclooxygenase-2 and production of interlukin-8 in hunan pulmonary epithelial cells. | Peptides 20080301 |
NSAIDs and breast cancer: a possible prevention and treatment strategy. | International journal of clinical practice 20080301 |
Modulation of celecoxib- and streptozotocin-induced experimental dementia of Alzheimer's disease by pitavastatin and donepezil. | Journal of psychopharmacology (Oxford, England) 20080301 |
A study of the pharmacokinetic interactions of the direct renin inhibitor aliskiren with allopurinol, celecoxib and cimetidine in healthy subjects. | Current medical research and opinion 20080301 |
Cyclooxygenase-2/PGE2 pathway facilitates pentylenetetrazol-induced seizures. | Epilepsy research 20080301 |
Perioperative versus postoperative celecoxib on patient outcomes after major plastic surgery procedures. | Anesthesia and analgesia 20080301 |
The effects of intrathecal cyclooxygenase-1, cyclooxygenase-2, or nonselective inhibitors on pain behavior and spinal Fos-like immunoreactivity. | Anesthesia and analgesia 20080301 |
Impact of prescriber nonresponse on patient representativeness. | Epidemiology (Cambridge, Mass.) 20080301 |
Celecoxib inhibits tumor growth and angiogenesis in an orthotopic implantation tumor model of human colon cancer. | Experimental oncology 20080301 |
Informatic tools and approaches in postmarketing pharmacovigilance used by FDA. | The AAPS journal 20080301 |
Pharmacogenetic and metabolic differences between dog breeds: their impact on canine medicine and the use of the dog as a preclinical animal model. | The AAPS journal 20080301 |
Novel strategies for the treatment of lung cancer: modulation of eicosanoids. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080220 |
Eicosanoid modulation in advanced lung cancer: cyclooxygenase-2 expression is a positive predictive factor for celecoxib + chemotherapy--Cancer and Leukemia Group B Trial 30203. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20080220 |
Synthesis and cyclooxygenase inhibitory activities of linear 1-(methanesulfonylphenyl or benzenesulfonamido)-2-(pyridyl)acetylene regioisomers. | Bioorganic & medicinal chemistry 20080215 |
Design and synthesis of 1,3-diarylurea derivatives as selective cyclooxygenase (COX-2) inhibitors. | Bioorganic & medicinal chemistry letters 20080215 |
Cyclooxygenase-2 inhibition inhibits c-Met kinase activity and Wnt activity in colon cancer. | Cancer research 20080215 |
Involvement of endogenous prostaglandin F2alpha on kainic acid-induced seizure activity through FP receptor: the mechanism of proconvulsant effects of COX-2 inhibitors. | Brain research 20080208 |
Alterations in spontaneous contractions of rat ileum and jejunum after peritonitis. | European journal of pharmacology 20080202 |
Phase-II study of dose attenuated schedule of irinotecan, capecitabine, and celecoxib in advanced colorectal cancer. | Cancer chemotherapy and pharmacology 20080201 |
A comparison of the effectiveness of selected non-steroidal anti-inflammatory drugs and their derivatives against cancer cells in vitro. | Cancer chemotherapy and pharmacology 20080201 |
Dose-dependent reduction of 3,2'-dimethyl-4-aminobiphenyl-derived DNA adducts in colon and liver of rats administered celecoxib. | Mutation research 20080201 |
5-Lipoxygenase and anandamide hydrolase (FAAH) mediate the antitumor activity of cannabidiol, a non-psychoactive cannabinoid. | Journal of neurochemistry 20080201 |
Celecoxib inhibits proliferation of retinal pigment epithelial and choroid-retinal endothelial cells by a cyclooxygenase-2-independent mechanism. | The Journal of pharmacology and experimental therapeutics 20080201 |
Morphine and ABT-594 (a nicotinic acetylcholine agonist) exert centrally mediated antinociception in the rat cyclophosphamide cystitis model of visceral pain. | The journal of pain : official journal of the American Pain Society 20080201 |
Vitamin E analog, alpha-tocopherol ether-linked acetic acid analog, alone and in combination with celecoxib, reduces multiplicity of ultraviolet-induced skin cancers in mice. | Anti-cancer drugs 20080201 |
Biologic markers of angiogenesis: circulating endothelial cells in patients with advanced malignancies treated on phase I protocol with metronomic chemotherapy and celecoxib. | Cancer investigation 20080201 |
Celecoxib to prevent restenosis--results from the COREA-TAXUS trial. | Expert opinion on pharmacotherapy 20080201 |
Differential effects of selective cyclooxygenase-2 inhibitors in inhibiting proliferation and induction of apoptosis in oral squamous cell carcinoma. | Oncology reports 20080201 |
Antiproliferative and proapoptotic effects of rapamycin and celecoxib in malignant melanoma cell lines. | Oncology reports 20080201 |
Cyclooxygenase-2 deficiency enhances Th2 immune responses and impairs neutrophil recruitment in hepatic ischemia/reperfusion injury. | Journal of immunology (Baltimore, Md. : 1950) 20080201 |
Pharmacogenetics: data, concepts and tools to improve drug discovery and drug treatment. | European journal of clinical pharmacology 20080201 |
Celecoxib analogs that lack COX-2 inhibitory function: preclinical development of novel anticancer drugs. | Expert opinion on investigational drugs 20080201 |
Erectile dysfunction induced probably by celecoxib. | Pharmacoepidemiology and drug safety 20080201 |
Aggravated endoplasmic reticulum stress as a basis for enhanced glioblastoma cell killing by bortezomib in combination with celecoxib or its non-coxib analogue, 2,5-dimethyl-celecoxib. | Cancer research 20080201 |
Metformin-induced lactic acidosis and acute pancreatitis precipitated by diuretic, celecoxib, and candesartan-associated acute kidney dysfunction. | Clinical toxicology (Philadelphia, Pa.) 20080201 |
Oral celecoxib versus oral diclofenac for post-perineal repair analgesia after spontaneous vaginal birth: a randomised trial. | The Australian & New Zealand journal of obstetrics & gynaecology 20080201 |
[Pre-clinical and clinical profiles of celecoxib, a new specific cyclooxygenase-2 inhibitor]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20080201 |
Update on rifampin and rifabutin drug interactions. | The American journal of the medical sciences 20080201 |
Cyclooxygenase (COX) and 5-lipoxygenase (5-LOX) selectivity of COX inhibitors. | Prostaglandins, leukotrienes, and essential fatty acids 20080201 |
Recurrent postoperative CRPS I in patients with abnormal preoperative sympathetic function. | The Journal of hand surgery 20080201 |
Effects of selective and non-selective COX inhibitors on antigen-induced release of prostanoid mediators and bronchoconstriction in the isolated perfused and ventilated guinea pig lung. | Prostaglandins, leukotrienes, and essential fatty acids 20080201 |
Tumor response to combination celecoxib and erlotinib therapy in non-small cell lung cancer is associated with a low baseline matrix metalloproteinase-9 and a decline in serum-soluble E-cadherin. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20080201 |
Inhibition of delayed rectifier potassium channels and induction of arrhythmia: a novel effect of celecoxib and the mechanism underlying it. | The Journal of biological chemistry 20080118 |
[Allergic reactions to nonsteroidal anti-inflammatory drugs]. | Revue medicale suisse 20080116 |
Celecoxib transiently inhibits cellular protein synthesis. | Biochemical pharmacology 20080115 |
Interaction between celecoxib and docetaxel or cisplatin in human cell lines of ovarian cancer and colon cancer is independent of COX-2 expression levels. | Biochemical pharmacology 20080115 |
New celecoxib derivatives as anti-inflammatory agents. | Journal of medicinal chemistry 20080110 |
Mathematical analysis of involvement ratio between central and peripheral COX-2 in rat pain models with two types of COX-2 inhibitors with different distribution, celecoxib and CIAA. | European journal of pharmacology 20080106 |
Preclinical pharmacology profile of CS-706, a novel cyclooxygenase-2 selective inhibitor, with potent antinociceptive and anti-inflammatory effects. | European journal of pharmacology 20080106 |
Nanostructured lipid carrier (NLC) based gel of celecoxib. | International journal of pharmaceutics 20080104 |
2-Amino-5-thiazolyl motif: a novel scaffold for designing anti-inflammatory agents of diverse structures. | European journal of medicinal chemistry 20080101 |
Synthesis and release of human cartilage matrix proteoglycans are differently regulated by nitric oxide and prostaglandin-E2. | Annals of the rheumatic diseases 20080101 |
Prostaglandin E2 systemic production in patients with asthma with and without aspirin hypersensitivity. | Thorax 20080101 |
Results of a pilot study of the effects of celecoxib on cancer cachexia in patients with cancer of the head, neck, and gastrointestinal tract. | Head & neck 20080101 |
Chemoprevention with special reference to inherited colorectal cancer. | Familial cancer 20080101 |
Involvement of LTB4 in zymosan-induced joint nociception in mice: participation of neutrophils and PGE2. | Journal of leukocyte biology 20080101 |
Lumiracoxib 400 mg compared with celecoxib 400 mg and placebo for treating pain following dental surgery: a randomized, controlled trial. | The journal of pain : official journal of the American Pain Society 20080101 |
Synthesis and biological evaluation of 2-trifluoromethyl/sulfonamido-5,6-diaryl substituted imidazo[2,1-b]-1,3,4-thiadiazoles: a novel class of cyclooxygenase-2 inhibitors. | Bioorganic & medicinal chemistry 20080101 |
The resistance to the tumor suppressive effects of COX inhibitors and COX-2 gene disruption in TRAMP mice is associated with the loss of COX expression in prostate tissue. | Carcinogenesis 20080101 |
Celecoxib disrupts the canonical apoptotic network in HTLV-I cells through activation of Bax and inhibition of PKB/Akt. | Apoptosis : an international journal on programmed cell death 20080101 |
Effect of cyclooxygenase and nitric oxide synthase inhibitors on streptozotocin-induced hyperalgesia in rats. | Pharmacology 20080101 |
Effects of nonsteroidal anti-inflammatory drugs on the expression of urokinase plasminogen activator and inhibitor and gelatinases in the early osteoarthritic knee of humans. | Clinical biochemistry 20080101 |
Celecoxib induced tumor cell radiosensitization by inhibiting radiation induced nuclear EGFR transport and DNA-repair: a COX-2 independent mechanism. | International journal of radiation oncology, biology, physics 20080101 |
Renal functional responses to ischaemia-reperfusion injury in normotensive and hypertensive rats following non-selective and selective cyclo-oxygenase inhibition with nitric oxide donation. | Clinical and experimental pharmacology & physiology 20080101 |
The effects of prostaglandin inhibition on whole-body ischemia-reperfusion in swine. | The American journal of emergency medicine 20080101 |
Prostaglandin inhibition and ischemia: where are the data? | The American journal of emergency medicine 20080101 |
Chemoprevention of arylamine-induced colorectal aberrant crypts. | Experimental biology and medicine (Maywood, N.J.) 20080101 |
Use of selective cyclooxygenase-2 inhibitors and nonselective nonsteroidal antiinflammatory drugs in high doses increases mortality and risk of reinfarction in patients with prior myocardial infarction. | The Journal of cardiovascular nursing 20080101 |
The effect of a selective cyclooxygenase-2 inhibitor (celecoxib) on chronic periodontitis. | Journal of periodontology 20080101 |
Response to Ray and colleagues: the called-for large clinical trial is already ongoing. | Gastroenterology 20080101 |
Modeling of corneal and retinal pharmacokinetics after periocular drug administration. | Investigative ophthalmology & visual science 20080101 |
Effect of eye pigmentation on transscleral drug delivery. | Investigative ophthalmology & visual science 20080101 |
Selective COX-2 inhibitor celecoxib combined with EGFR-TKI ZD1839 on non-small cell lung cancer cell lines: in vitro toxicity and mechanism study. | Medical oncology (Northwood, London, England) 20080101 |
Urinary human L-FABP is a potential biomarker to predict COX-inhibitor-induced renal injury. | Nephron. Experimental nephrology 20080101 |
Etoricoxib-induced erythema-multiforme-like eruption. | Dermatology (Basel, Switzerland) 20080101 |
Use of cox-2 inhibitors in patients with retinal venous occlusive disease. | Retina (Philadelphia, Pa.) 20080101 |
Interpleural analgesia in breast reconstruction. | Scandinavian journal of plastic and reconstructive surgery and hand surgery 20080101 |
Costs and effects of various analgesic treatments for patients with rheumatoid arthritis and osteoarthritis in the Netherlands. | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20080101 |
Prevalence of anaemia in older persons: systematic review. | BMC geriatrics 20080101 |
Rethinking the threats to scientific balance in contexts of litigation and regulation. | Environmental health perspectives 20080101 |
Faecal blood loss with aspirin, nonsteroidal anti-inflammatory drugs and cyclo-oxygenase-2 selective inhibitors: systematic review of randomized trials using autologous chromium-labelled erythrocytes. | Arthritis research & therapy 20080101 |
Key regulatory molecules of cartilage destruction in rheumatoid arthritis: an in vitro study. | Arthritis research & therapy 20080101 |
No effect of one-year treatment with indomethacin on Alzheimer's disease progression: a randomized controlled trial. | PloS one 20080101 |
Intracellular effects of NSAIDs/ASA in oxidatively stressed human lens epithelial cells in culture. | Ophthalmic research 20080101 |
Cyclooxygenase-2 overexpression is common in serrated and non-serrated colorectal adenoma, but uncommon in hyperplastic polyp and sessile serrated polyp/adenoma. | BMC cancer 20080101 |
Neoadjuvant therapy with celecoxib to women with early stage breast cancer. | Neoplasma 20080101 |
Are N-of-1 trials an economically viable option to improve access to selected high cost medications? The Australian experience. | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20080101 |
NF-kappa B genes have a major role in inflammatory breast cancer. | BMC cancer 20080101 |
What do we know about communicating risk? A brief review and suggestion for contextualising serious, but rare, risk, and the example of cox-2 selective and non-selective NSAIDs. | Arthritis research & therapy 20080101 |
OTC analgesics and drug interactions: clinical implications. | Osteopathic medicine and primary care 20080101 |
Protective effects of cyclooxygenase-2 inhibitors on narrow-band ultraviolet B-irradiated epidermal Ia+ Langerhans cells and Thy-1+ dendritic epidermal T cells in mice. | Photochemistry and photobiology 20080101 |
Cyclooxygenase-2 inhibitor nimesulide blocks ultraviolet B-induced photocarcinogenesis in SKH-1 hairless mice. | Photochemistry and photobiology 20080101 |
Celecoxib concentration predicts decrease in prostaglandin E2 concentrations in nipple aspirate fluid from high risk women. | BMC cancer 20080101 |
Design, power, and interpretation of studies in the standard murine model of ALS. | Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases 20080101 |
Chemopreventive effects of celecoxib are limited to hormonally responsive mammary carcinomas in the neu-induced retroviral rat model. | Breast cancer research : BCR 20080101 |
Comparison of protein expression by isotope-coded affinity tag labeling. | Methods in molecular biology (Clifton, N.J.) 20080101 |
Compositions for treatment of cancer and inflammation. | Recent patents on anti-cancer drug discovery 20080101 |
Selective cyclooxygenase-2 inhibitor prevents reduction of trabecular bone mass in collagen-induced arthritic mice in association with suppression of RANKL/OPG ratio and IL-6 mRNA expression in synovial tissues but not in bone marrow cells. | Journal of bone and mineral metabolism 20080101 |
The role of interleukin-1 in neuroinflammation and Alzheimer disease: an evolving perspective. | Journal of neuroinflammation 20080101 |
Preoperative treatment with a non-steroidal anti-inflammatory drug (NSAID) increases tumor tissue infiltration of seemingly activated immune cells in colorectal cancer. | Cancer immunity 20080101 |
Cardiovascular disease in patients with rheumatoid arthritis: results from the QUEST-RA study. | Arthritis research & therapy 20080101 |
Long-term retention on treatment with lumiracoxib 100 mg once or twice daily compared with celecoxib 200 mg once daily: a randomised controlled trial in patients with osteoarthritis. | BMC musculoskeletal disorders 20080101 |
Nimesulide is a selective COX-2 inhibitory, atypical non-steroidal anti-inflammatory drug. | Current medicinal chemistry 20080101 |
Effect of circulation on the disposition and ocular tissue distribution of 20 nm nanoparticles after periocular administration. | Molecular vision 20080101 |
Preclinical and clinical studies of novel breast cancer drugs targeting molecules involved in protein kinase C signaling, the putative metastasis-suppressor gene Cap43 and the Y-box binding protein-1. | Current medicinal chemistry 20080101 |
Analgesic effectiveness of celecoxib and diclofenac in patients with osteoarthritis of the hip requiring joint replacement surgery: a 12-week, multicenter, randomized, double-blind, parallel-group, double-dummy, noninferiority study. | Clinical therapeutics 20080101 |
Malignant transformation of normal enterocytes following downregulation of Bak expression. | Digestion 20080101 |
Extract of radix curcumae prevents gastric cancer in rats. | Digestion 20080101 |
Interventions designed to improve the quality and efficiency of medication use in managed care: a critical review of the literature - 2001-2007. | BMC health services research 20080101 |
Effect of nonsteroidal anti-inflammatory drugs and the procarcinogen 1,2-dimethylhydrazine on the antioxidant defense system. | International journal of toxicology 20080101 |
Diabetic retinopathy: an update. | Indian journal of ophthalmology 20080101 |
Discontinuation rates in clinical trials in musculoskeletal pain: meta-analysis from etoricoxib clinical trial reports. | Arthritis research & therapy 20080101 |
Phase II trial of isoflavone in prostate-specific antigen recurrent prostate cancer after previous local therapy. | BMC cancer 20080101 |
Dissemination of Strongyloides stercoralis in a patient with systemic lupus erythematosus after initiation of albendazole: a case report. | Journal of medical case reports 20080101 |
COX-2 inhibition is neither necessary nor sufficient for celecoxib to suppress tumor cell proliferation and focus formation in vitro. | Molecular cancer 20080101 |
Neuroinflammatory response to lipopolysaccharide is exacerbated in mice genetically deficient in cyclooxygenase-2. | Journal of neuroinflammation 20080101 |
Molecular analysis of the effects of Piroxicam and Cisplatin on mesothelioma cells growth and viability. | Journal of translational medicine 20080101 |
Patients with rheumatoid arthritis have an altered circulatory aggrecan profile. | BMC musculoskeletal disorders 20080101 |
Perioperative celecoxib administration for pain management after total knee arthroplasty - a randomized, controlled study. | BMC musculoskeletal disorders 20080101 |
Quantitative endoscopy in the chemoprevention of Barrett's Esophagus Trial. | Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20080101 |
Use and misuse of the p-value. | Bulletin of the NYU hospital for joint diseases 20080101 |
Superiority, equivalence, and non-inferiority trials. | Bulletin of the NYU hospital for joint diseases 20080101 |
Antioxidative effects of nonsteroidal anti-inflammatory drugs during the initiation stages of experimental colon carcinogenesis in rats. | Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20080101 |
Peroxisome proliferator-activated receptors and progression of colorectal cancer. | PPAR research 20080101 |
Episode-specific differential gene expression of peripheral blood mononuclear cells in rapid cycling supports novel treatment approaches. | Molecular medicine (Cambridge, Mass.) 20080101 |
Fibrin sealant does not decrease seroma output or time to drain removal following inguino-femoral lymph node dissection in melanoma patients: a randomized controlled trial (NCT00506311). | World journal of surgical oncology 20080101 |
Quality of anticoagulation and use of warfarin-interacting medications in long-term care: a chart review. | BMC geriatrics 20080101 |
Effect of different non-steroidal anti-inflammatory drugs, aspirin, nimesulide and celecoxib on the disaccharide hydrolases and histoarchitecture of the rat intestinal brush border membrane. | Nutricion hospitalaria 20080101 |
Skin permeation mechanism and bioavailability enhancement of celecoxib from transdermally applied nanoemulsion. | Journal of nanobiotechnology 20080101 |
Cancer chemoprevention: a summary of the current evidence. | Anticancer research 20080101 |
Pro-apoptotic effect of nonsteroidal anti-inflammatory drugs on synovial fibroblasts. | Modern rheumatology 20080101 |
PPAR Ligands as Potential Modifiers of Breast Carcinoma Outcomes. | PPAR research 20080101 |
A pharmacological analysis of the possible role of vasoactive mediators in compensatory coronary blood flow. | Experimental and clinical cardiology 20080101 |
A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin for treatment of osteoarthritis of the knee. | Arthritis research & therapy 20080101 |
Clinical effects of Garcinia kola in knee osteoarthritis. | Journal of orthopaedic surgery and research 20080101 |
Role of peroxisome proliferator-activated receptor alpha in the control of cyclooxygenase 2 and vascular endothelial growth factor: involvement in tumor growth. | PPAR research 20080101 |
Effects of COX-2 inhibition on expression of vascular endothelial growth factor and interleukin-8 in lung cancer cells. | BMC cancer 20080101 |
Virtual screening for novel COX-2 inhibitors using the ZINC database. | Bioinformation 20080101 |
Ameliorative role of Atorvastatin and Pitavastatin in L-Methionine induced vascular dementia in rats. | BMC pharmacology 20080101 |
Cigarette smoke induces endoplasmic reticulum stress and the unfolded protein response in normal and malignant human lung cells. | BMC cancer 20080101 |
Similar reductions in the risk of human colon cancer by selective and nonselective cyclooxygenase-2 (COX-2) inhibitors. | BMC cancer 20080101 |
Micro-CT imaging analysis for the effect of celecoxib, a cyclooxygenase-2 inhibitor, on inflammatory bone destruction in adjuvant arthritis rats. | Journal of bone and mineral metabolism 20080101 |
Upregulated miR-146a expression in peripheral blood mononuclear cells from rheumatoid arthritis patients. | Arthritis research & therapy 20080101 |
Anti-inflammatory effects of Radix Gentianae Macrophyllae (Qinjiao), Rhizoma Coptidis (Huanglian) and Citri Unshiu Pericarpium (Wenzhou migan) in animal models. | Chinese medicine 20080101 |
Potential effects of chondroitin sulfate on joint swelling: a GAIT report. | Osteoarthritis and cartilage 20080101 |
A 6-week, multicentre, randomised, double-blind, double-dummy, active-controlled, clinical safety study of lumiracoxib and rofecoxib in osteoarthritis patients. | BMC musculoskeletal disorders 20080101 |
Fast track open partial nephrectomy: reduced postoperative length of stay with a goal-directed pathway does not compromise outcome. | Advances in urology 20080101 |
Long-term efficacy and safety of lumiracoxib 100 mg: an open-label extension of a 13-week randomized controlled trial in patients with primary osteoarthritis of the knee. | Clinical and experimental rheumatology 20080101 |
Non-steroidal anti-inflammatory drugs, Cyclooxygenase-2 inhibitors and paracetamol use in Queensland and in the whole of Australia. | BMC health services research 20080101 |
Lipooxygenase inhibition in osteoarthritis: a potential symptomatic and disease modifying effect? | Arthritis research & therapy 20080101 |
Effects of celecoxib and nimesulide on the proliferation of ectopic endometrial stromal cells in vitro. | The Journal of international medical research 20080101 |
Anti cancer effects of curcumin: cycle of life and death. | Cell division 20080101 |
Concomitant use of gastroprotective drugs among elderly NSAID/COX-2 selective inhibitor users: a nationwide register-based study. | Clinical drug investigation 20080101 |
NSAID use in individuals at risk of renal adverse events: an observational study to investigate trends in Australian veterans. | Drug safety 20080101 |
Takotsubo cardiomyopathy associated with anesthesia: three case reports. | Cases journal 20080101 |
Three-dimensional growth as multicellular spheroid activates the proangiogenic phenotype of colorectal carcinoma cells via LFA-1-dependent VEGF: implications on hepatic micrometastasis. | Journal of translational medicine 20080101 |
uPA is upregulated by high dose celecoxib in women at increased risk of developing breast cancer. | BMC cancer 20080101 |
HPV16 E7-dependent transformation activates NHE1 through a PKA-RhoA-induced inhibition of p38alpha. | PloS one 20080101 |
Finding multiple target optimal intervention in disease-related molecular network. | Molecular systems biology 20080101 |
Celecoxib inhibits apurinic/apyrimidinic endonuclease-1 expression and prevents gastric cancer in Helicobacter pylori-infected mongolian gerbils. | Digestion 20080101 |
Antitumor enhancement of celecoxib, a selective Cyclooxygenase-2 inhibitor, in a Lewis lung carcinoma expressing Cyclooxygenase-2. | Journal of experimental & clinical cancer research : CR 20080101 |
Combination chemoprevention of intestinal carcinogenesis in a murine model of familial adenomatous polyposis. | Nutrition and cancer 20080101 |
New horizons and perspectives in the treatment of osteoarthritis. | Arthritis research & therapy 20080101 |
Nitric oxide and cardiovascular effects: new insights in the role of nitric oxide for the management of osteoarthritis. | Arthritis research & therapy 20080101 |
Inflammaging as a prodrome to Alzheimer's disease. | Journal of neuroinflammation 20080101 |
Cost-effectiveness analysis for joint pain treatment in patients with osteoarthritis treated at the Instituto Mexicano del Seguro Social (IMSS): Comparison of nonsteroidal anti-inflammatory drugs (NSAIDs) vs. cyclooxygenase-2 selective inhibitors. | Cost effectiveness and resource allocation : C/E 20080101 |
Celecoxib accelerates functional recovery after sciatic nerve crush in the rat. | Journal of brachial plexus and peripheral nerve injury 20080101 |
PPARgamma and Agonists against Cancer: Rational Design of Complementation Treatments. | PPAR research 20080101 |
Discrepancies in sample size calculations and data analyses reported in randomised trials: comparison of publications with protocols. | BMJ (Clinical research ed.) 20080101 |
The NIH Glucosamine/Chondroitin Arthritis Intervention Trial (GAIT). | Journal of pain & palliative care pharmacotherapy 20080101 |
Effect of cyclooxygenase and nitric oxide synthase inhibitors on vincristine induced hyperalgesia in rats. | Pharmacological reports : PR 20080101 |
Overuse of non-prescription analgesics by dental clinic patients. | BMC oral health 20080101 |
Incremental cost effectiveness of proton pump inhibitors for the prevention of non-steroidal anti-inflammatory drug ulcers: a pharmacoeconomic analysis linked to a case-control study. | Arthritis research & therapy 20080101 |
Quantitative effects of tumescent infiltration and bupivicaine injection in decreasing postoperative pain in submuscular breast augmentation. | Aesthetic surgery journal 20080101 |
Evaluation of symptomatic slow-acting drugs in osteoarthritis using the GRADE system. | BMC musculoskeletal disorders 20080101 |
Evaluation of GW406381 for treatment of osteoarthritis of the knee: two randomized, controlled studies. | Medscape journal of medicine 20080101 |
[Cardiovascular risk of cyclooxygenase selective inhibitors]. | Revista medica del Instituto Mexicano del Seguro Social 20080101 |
Effect of non-steroidal anti-inflammatory drugs and the pro-carcinogen 1,2 dimethylhydrazine on the rat intestinal membrane structure and function. | Nutricion hospitalaria 20080101 |
Low-dose oral metronomic chemotherapy prevents mobilization of endothelial progenitor cells into the blood of cancer patients. | In vivo (Athens, Greece) 20080101 |
Factors influencing effects of specific COX-2 inhibitor NSAIDs on growth and differentiation of mouse osteoblasts on titanium surfaces. | The International journal of oral & maxillofacial implants 20080101 |
Combination Therapy of PPARgamma Ligands and Inhibitors of Arachidonic Acid in Lung Cancer. | PPAR research 20080101 |
Influence of COX-2-induced PGE2 on the initiation and progression of tail regeneration in Northern House Gecko, Hemidactylus flaviviridis. | Folia biologica 20080101 |
FTIR studies on differential intermolecular association in crystalline and amorphous states of structurally related non-steroidal anti-inflammatory drugs. | Molecular pharmaceutics 20080101 |
Local massage with topical analgesic, a novel treatment modality for temporomandibular muscular pain, a case study report of 5 consecutive cases. | The open orthopaedics journal 20080101 |
Continuing medical education. | Indian journal of psychiatry 20080101 |
Antidepressant-like activity of tramadol in mice. | Indian journal of psychiatry 20080101 |
Molecular mechanisms underlying electroconvulsive therapy-induced amnestic deficits: A decade of research. | Indian journal of psychiatry 20080101 |
Antiinflammatory, analgesic and antipyretic activity of certain thiazolidinones. | Indian journal of pharmaceutical sciences 20080101 |
Dose-response assessment of the anti-cancer efficacy of soy isoflavones in dimethylhydrazine-treated rats fed 6% fructooligosaccharide. | Nutrition research and practice 20080101 |
Novel colon targeted drug delivery system using natural polymers. | Indian journal of pharmaceutical sciences 20080101 |
Psychological factors in asthma. | Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20080101 |
Aspirin-exacerbated asthma. | Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20080101 |
Relationship between arachidonic acid pathway and human renal cell carcinoma. | OncoTargets and therapy 20080101 |
Preemptive versus postoperative lumiracoxib for analgesia in ambulatory arthroscopic knee surgery. | Journal of pain research 20080101 |
Response Surface Methodology for the Optimization of Celecoxib Self-microemulsifying Drug delivery System. | Indian journal of pharmaceutical sciences 20080101 |
Potential contribution of aspirin to cancer control programmes. | Ecancermedicalscience 20080101 |
Rethinking statistical approaches to evaluating drug safety. | Yonsei medical journal 20071231 |
Sulindac prevents esophageal adenocarcinomas induced by gastroduodenal reflux in rats. | Yonsei medical journal 20071231 |
Pharmacological nature of nicotine-induced contraction in the rat basilar artery: involvement of arachidonic acid metabolites. | European journal of pharmacology 20071222 |
Are COX-2 inhibitors preferable to non-selective non-steroidal anti-inflammatory drugs in patients with risk of cardiovascular events taking low-dose aspirin? | Lancet (London, England) 20071222 |
Selective inhibition of cyclooxygenase-2 exacerbates methamphetamine-induced dopamine depletion in the striatum in rats. | Neuroscience 20071219 |
Response to dual blockade of epidermal growth factor receptor (EGFR) and cycloxygenase-2 in nonsmall cell lung cancer may be dependent on the EGFR mutational status of the tumor. | Cancer 20071215 |
Structure-based design, synthesis, and biological evaluation of indomethacin derivatives as cyclooxygenase-2 inhibiting nitric oxide donors. | Journal of medicinal chemistry 20071213 |
Direct non-cyclooxygenase-2 targets of celecoxib and their potential relevance for cancer therapy. | British journal of cancer 20071203 |
COX-2 inhibitor celecoxib prevents chronic morphine-induced promotion of angiogenesis, tumour growth, metastasis and mortality, without compromising analgesia. | British journal of cancer 20071203 |
Osteoid osteoma of the dens axis. | European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society 20071201 |
A comparison of the efficacy and safety of celecoxib 200 mg and celecoxib 400 mg once daily in treating the signs and symptoms of psoriatic arthritis. | Seminars in arthritis and rheumatism 20071201 |
Low-intensity pulsed ultrasound and nonsteroidal anti-inflammatory drugs have opposing effects during stress fracture repair. | Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20071201 |
Protective effects of cyclooxygenase-2 gene inactivation against peripheral nerve dysfunction and intraepidermal nerve fiber loss in experimental diabetes. | Diabetes 20071201 |
Carbonic anhydrase inhibitors: cloning, characterization, and inhibition studies of the cytosolic isozyme III with sulfonamides. | Bioorganic & medicinal chemistry 20071201 |
Orthodontic tooth movement after different coxib therapies. | European journal of orthodontics 20071201 |
Potent inhibition of in vivo angiogenesis and tumor growth by a novel cyclooxygenase-2 inhibitor, enoic acanthoic acid. | Cancer science 20071201 |
The what, why and how of aromatase inhibitors: hormonal agents for treatment and prevention of breast cancer. | International journal of clinical practice 20071201 |
Effects of selective COX-2 inhibition on prostanoids and platelet physiology in young healthy volunteers. | Journal of thrombosis and haemostasis : JTH 20071201 |
Effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs on urinary sodium excretion, blood pressure, and other renal function indicators in elderly subjects consuming a controlled sodium diet. | Journal of clinical pharmacology 20071201 |
Synthesis, in vitro inhibitory activity towards COX-2 and haemolytic activity of derivatives of esculentoside A. | Bioorganic & medicinal chemistry letters 20071201 |
Early detection of adverse drug events within population-based health networks: application of sequential testing methods. | Pharmacoepidemiology and drug safety 20071201 |
Patterns of analgesic and anti-inflammatory medicine use by Australian veterans. | Internal medicine journal 20071201 |
A randomized trial of a 6-week course of celecoxib on proteinuria in diabetic kidney disease. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20071201 |
Cardiovascular thromboembolic adverse effects associated with cyclooxygenase-2 selective inhibitors and nonselective antiinflammatory drugs. | Anesthesia and analgesia 20071201 |
Lipoperoxidation and cyclooxygenase enzyme inhibitory piperidine alkaloids from Cassia spectabilis green fruits. | Journal of natural products 20071201 |
Hyperexpression of cyclooxygenase 2 in the lupus immune system and effect of cyclooxygenase 2 inhibitor diet therapy in a murine model of systemic lupus erythematosus. | Arthritis and rheumatism 20071201 |
Collagen-induced arthritis as a model of hyperalgesia: functional and cellular analysis of the analgesic actions of tumor necrosis factor blockade. | Arthritis and rheumatism 20071201 |
Metronomic antiangiogenic therapy with capecitabine and celecoxib in advanced tumor patients--results of a phase II study. | Onkologie 20071201 |
Aliskiren--an orally active renin inhibitor. Review of pharmacology, pharmacodynamics, kinetics, and clinical potential in the treatment of hypertension. | Vascular health and risk management 20071201 |
Glucosamine hydrochloride for the treatment of osteoarthritis symptoms. | Clinical interventions in aging 20071201 |
The effects of some nonsteroidal anti-inflammatory drugs on experimental induced gastric ulcers in rats. | Inflammopharmacology 20071201 |
[What is new about nonsteroidal antiinflamatory drugs?]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20071201 |
Update on the treatment of ankylosing spondylitis. | Therapeutics and clinical risk management 20071201 |
Anti-inflammatory and immune therapy for Alzheimer's disease: current status and future directions. | Current neuropharmacology 20071201 |
Cyclooxygenase-2 overexpression abrogates the antiproliferative effects of TGF-beta. | British journal of cancer 20071119 |
Hospitalization for gastrointestinal adverse events attributable to the use of low-dose aspirin among patients 50 years or older also using non-steroidal anti-inflammatory drugs: a retrospective cohort study. | Alimentary pharmacology & therapeutics 20071115 |
Gene expression analysis proposes alternative pathways for the mechanism by which celecoxib selectively inhibits the growth of transformed but not normal enterocytes. | Clinical cancer research : an official journal of the American Association for Cancer Research 20071115 |
Weekly administration of docetaxel in combination with estramustine and celecoxib in patients with advanced hormone-refractory prostate cancer: final results from a phase II study. | British journal of cancer 20071105 |
Role of oxidative stress in celecoxib-induced renal damage in wistar rats. | Digestive diseases and sciences 20071101 |
What happened to the prescribing of other COX-2 inhibitors, paracetamol and non-steroidal anti-inflammatory drugs when rofecoxib was withdrawn in Australia? | Pharmacoepidemiology and drug safety 20071101 |
2-amino-N-{4-[5-(2-phenanthrenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]-phenyl} acetamide (OSU-03012), a celecoxib derivative, directly targets p21-activated kinase. | Molecular pharmacology 20071101 |
CCAAT/enhancer binding protein homologous protein-dependent death receptor 5 induction and ubiquitin/proteasome-mediated cellular FLICE-inhibitory protein down-regulation contribute to enhancement of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by dimethyl-celecoxib in human non small-cell lung cancer cells. | Molecular pharmacology 20071101 |
Inhibition of RIP and c-FLIP enhances TRAIL-induced apoptosis in pancreatic cancer cells. | Cellular signalling 20071101 |
Novel therapeutic strategies combining antihormonal and biological targeted therapies in breast cancer: focus on clinical trials and perspectives. | Critical reviews in oncology/hematology 20071101 |
Effects of anti-inflammatory drugs on proliferation, cytotoxicity and osteogenesis in bone marrow mesenchymal stem cells. | Biochemical pharmacology 20071101 |
Apoptosis of murine lupus T cells induced by the selective cyclooxygenase-2 inhibitor celecoxib: molecular mechanisms and therapeutic potential. | International immunopharmacology 20071101 |
Influence of polymers on the bioavailability of microencapsulated celecoxib. | Journal of microencapsulation 20071101 |
Celecoxib after the onset of reperfusion reduces apoptosis in the amygdala. | Apoptosis : an international journal on programmed cell death 20071101 |
Cytometric assessment of DNA damage by exogenous and endogenous oxidants reports aging-related processes. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20071101 |
Electrical impedance myography to assess outcome in amyotrophic lateral sclerosis clinical trials. | Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology 20071101 |
Cardiovascular effects of cyclooxygenase-2 inhibitors. | Current opinion in gastroenterology 20071101 |
Action of celecoxib on hepatic metabolic changes induced by the Walker-256 tumour in rats. | Basic & clinical pharmacology & toxicology 20071101 |
CYP2C9 structure-metabolism relationships: substrates, inhibitors, and metabolites. | Journal of medicinal chemistry 20071101 |
Cyclooxygenase-2 inhibitors. 1,5-diarylpyrrol-3-acetic esters with enhanced inhibitory activity toward cyclooxygenase-2 and improved cyclooxygenase-2/cyclooxygenase-1 selectivity. | Journal of medicinal chemistry 20071101 |
Effect of celecoxib and novel agent LC-1 in a hamster model of lung cancer. | The Journal of surgical research 20071101 |
Preoperative growth inhibition of human gastric adenocarcinoma treated with a combination of celecoxib and octreotide. | Acta pharmacologica Sinica 20071101 |
Celecoxib prevented development of heterotopic ossification better than Ibuprofen after total hip replacement. | The Journal of bone and joint surgery. American volume 20071101 |
Clinical inquiries. Do COX-2 inhibitors worsen renal function? | The Journal of family practice 20071101 |
Liver transplantation for nonsteroidal anti-inflammatory drug-induced liver failure: nimesulide as the first implicated compound. | European journal of gastroenterology & hepatology 20071101 |
Effects of aspirin and celecoxib on rigidity in a rat model of Parkinson's disease. | Pakistan journal of biological sciences : PJBS 20071101 |
Randomized, controlled trial of irinotecan plus infusional, bolus, or oral fluoropyrimidines in first-line treatment of metastatic colorectal cancer: results from the BICC-C Study. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20071020 |
The effect of celecoxib on tissue factor expression in pancreatic cancer cells. | Chinese medical journal 20071020 |
In vitro and in vivo reversal of resistance to 5-fluorouracil in colorectal cancer cells with a novel stealth double-liposomal formulation. | British journal of cancer 20071008 |
Cultivars of apple fruits that are not marketed with potential for anthocyanin production. | Journal of agricultural and food chemistry 20071003 |
Relative non-steroidal anti-inflammatory drug (NSAID) antiproliferative activity is mediated through p21-induced G1 arrest and E2F inhibition. | Molecular carcinogenesis 20071001 |
Combined use of crystalline salt forms and precipitation inhibitors to improve oral absorption of celecoxib from solid oral formulations. | Journal of pharmaceutical sciences 20071001 |
Covalent binding of rofecoxib, but not other cyclooxygenase-2 inhibitors, to allysine aldehyde in elastin of human aorta. | Drug metabolism and disposition: the biological fate of chemicals 20071001 |
The cardioprotection of the late phase of ischemic preconditioning is enhanced by postconditioning via a COX-2-mediated mechanism in conscious rats. | American journal of physiology. Heart and circulatory physiology 20071001 |
Effects of celecoxib on the reversal of multidrug resistance in human gastric carcinoma by downregulation of the expression and activity of P-glycoprotein. | Anti-cancer drugs 20071001 |
COX-2 inhibitor. | Rheumatology (Oxford, England) 20071001 |
Radiosensitization of human glioma cells by cyclooxygenase-2 (COX-2) inhibition: independent on COX-2 expression and dependent on the COX-2 inhibitor and sequence of administration. | International journal of radiation biology 20071001 |
Effect of hypericin-mediated photodynamic therapy on the expression of vascular endothelial growth factor in human nasopharyngeal carcinoma. | International journal of molecular medicine 20071001 |
Preliminary results of the Prostacox phase II trial in hormonal refractory prostate cancer. | BJU international 20071001 |
Celecoxib versus magnesium sulfate to arrest preterm labor: randomized trial. | The journal of obstetrics and gynaecology research 20071001 |
Exisulind in combination with celecoxib modulates epidermal growth factor receptor, cyclooxygenase-2, and cyclin D1 against prostate carcinogenesis: in vivo evidence. | Clinical cancer research : an official journal of the American Association for Cancer Research 20071001 |
Targeting cyclooxygenase-2 and the epidermal growth factor receptor for the prevention and treatment of intestinal cancer. | Cancer research 20071001 |
Celecoxib plus aspirin versus naproxen and lansoprazole plus aspirin: a randomized, double-blind, endoscopic trial. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20071001 |
COX-2 and NF-KB overexpression is common in pancreatic cancer but does not predict for COX-2 inhibitors activity in combination with gemcitabine and oxaliplatin. | American journal of clinical oncology 20071001 |
[Current issues of NSAID-induced gastrointestinal ulcer in Japan]. | Nihon rinsho. Japanese journal of clinical medicine 20071001 |
[The choice of selective COX-2 inhibitors]. | Nihon rinsho. Japanese journal of clinical medicine 20071001 |
[Inhibitory effects of cyclooxygenase-2 inhibitor celecoxib on the proliferation of hepatocellular carcinoma cells]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20071001 |
Effects of celecoxib on blood loss, pain, and recovery of function after total knee replacement: a randomized placebo-controlled trial. | Acta orthopaedica 20071001 |
Niosomal gel for site-specific sustained delivery of anti-arthritic drug: in vitro-in vivo evaluation. | Current drug delivery 20071001 |
Selective COX-2 inhibitors, NSAIDs and cardiovascular events - is celecoxib the safest choice? | Therapeutics and clinical risk management 20071001 |
Progress update: Pharmacological treatment of Alzheimer's disease. | Neuropsychiatric disease and treatment 20071001 |
Celecoxib induces MRP-4 in lung cancer cells: therapeutic implications. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20070920 |
A cyclooxygenase-2 inhibitor ameliorates behavioral impairments induced by striatal administration of epidermal growth factor. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20070919 |
'Bridged' stilbene derivatives as selective cyclooxygenase-1 inhibitors. | Bioorganic & medicinal chemistry 20070915 |
Atorvastatin and celecoxib inhibit prostate PC-3 tumors in immunodeficient mice. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070915 |
PDK-1/AKT pathway as a novel therapeutic target in rhabdomyosarcoma cells using OSU-03012 compound. | British journal of cancer 20070911 |
CYP2C9 structure-metabolism relationships: optimizing the metabolic stability of COX-2 inhibitors. | Journal of medicinal chemistry 20070906 |
Efficacy and safety of epicutaneous ketoprofen in Transfersome (IDEA-033) versus oral celecoxib and placebo in osteoarthritis of the knee: multicentre randomised controlled trial. | Annals of the rheumatic diseases 20070901 |
The ubiquitin- and proteasome-dependent degradation of COX-2 is regulated by the COP9 signalosome and differentially influenced by coxibs. | Journal of molecular medicine (Berlin, Germany) 20070901 |
Aggravation by selective COX-1 and COX-2 inhibitors of dextran sulfate sodium (DSS)-induced colon lesions in rats. | Digestive diseases and sciences 20070901 |
Reduced survivin expression and tumor cell survival during chronic hypoxia and further cytotoxic enhancement by the cyclooxygenase-2 inhibitor celecoxib. | Journal of biomedical science 20070901 |
Efficacy and patterns of failure for locally advanced cancer of the cervix treated with celebrex (celecoxib) and chemoradiotherapy in RTOG 0128. | International journal of radiation oncology, biology, physics 20070901 |
Selective COX-2 inhibitors, eicosanoid synthesis and clinical outcomes: a case study of system failure. | Lipids 20070901 |
Signaling pathways involved in cyclooxygenase-2 induction by hepatocyte growth factor in non small-cell lung cancer. | Molecular pharmacology 20070901 |
DNA-PKcs-dependent modulation of cellular radiosensitivity by a selective cyclooxygenase-2 inhibitor. | International journal of radiation oncology, biology, physics 20070901 |
Obturator versus femoral nerve block for analgesia after total knee arthroplasty. | Anesthesia and analgesia 20070901 |
Effects of celecoxib on voltage-gated calcium channel currents in rat pheochromocytoma (PC12) cells. | Pharmacological research 20070901 |
OARSI recommendations for the management of hip and knee osteoarthritis, part I: critical appraisal of existing treatment guidelines and systematic review of current research evidence. | Osteoarthritis and cartilage 20070901 |
Randomised, open label, controlled trial of celecoxib in the treatment of acute migraine. | Singapore medical journal 20070901 |
Safety of intravitreal injections in patients receiving warfarin anticoagulation. | American journal of ophthalmology 20070901 |
Development of spray-dried co-precipitate of amorphous celecoxib containing storage and compression stabilizers. | Acta pharmaceutica (Zagreb, Croatia) 20070901 |
Design, development and evaluation of novel nanoemulsion formulations for transdermal potential of celecoxib. | Acta pharmaceutica (Zagreb, Croatia) 20070901 |
Resolution of hydronephrosis due to massive mesenteric fibromatosis using cyclo-oxygenase 2 inhibitors. | Urology 20070901 |
Rosiglitazone: a disappointing DREAM. | Future cardiology 20070901 |
Cyclooxygenase-2 promotes cell proliferation, migration and invasion in U2OS human osteosarcoma cells. | Experimental & molecular medicine 20070831 |
COX2 genetic variation, NSAIDs, and advanced prostate cancer risk. | British journal of cancer 20070820 |
Coronary restenosis: a new strategy for the future? | Lancet (London, England) 20070818 |
Effect of celecoxib on restenosis after coronary angioplasty with a Taxus stent (COREA-TAXUS trial): an open-label randomised controlled study. | Lancet (London, England) 20070818 |
Synergistic antitumor effects of celecoxib with 5-fluorouracil depend on IFN-gamma. | International journal of cancer 20070815 |
OSU-03012, a novel celecoxib derivative, is cytotoxic to myeloma cells and acts through multiple mechanisms. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070815 |
Cyclooxygenase-2 inhibitor ameliorates ureteric damage in rats with obstructed uropathy. | European journal of pharmacology 20070813 |
Cyclovirobuxine D ameliorates acute myocardial ischemia by K(ATP) channel opening, nitric oxide release and anti-thrombosis. | European journal of pharmacology 20070813 |
CCR1 and CCR5 chemokine receptors are involved in fever induced by LPS (E. coli) and RANTES in rats. | Brain research 20070803 |
Channelling of COX-2 inhibitors to patients at higher gastrointestinal risk but not at lower cardiovascular risk: the Cox2 inhibitors and tNSAIDs description of users (CADEUS) study. | Pharmacoepidemiology and drug safety 20070801 |
Cyclo-oxygenase-independent inhibition of apoptosis and stimulation of proliferation by leptin in human colon cancer cells. | Digestive diseases and sciences 20070801 |
Dipyrone elicits substantial inhibition of peripheral cyclooxygenases in humans: new insights into the pharmacology of an old analgesic. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20070801 |
Antiinflammatory effects of a combined herbal preparation (RAH13) of Phellodendron amurense and Coptis chinensis in animal models of inflammation. | Phytotherapy research : PTR 20070801 |
The effects of common anti-inflammatory drugs on the healing rat patellar tendon. | The American journal of sports medicine 20070801 |
Possible cross-regulation of the E prostanoid receptors. | Molecular carcinogenesis 20070801 |
Effects of nimesulide on pain and on synovial fluid concentrations of substance P, interleukin-6 and interleukin-8 in patients with knee osteoarthritis: comparison with celecoxib. | International journal of clinical practice 20070801 |
Design, synthesis and pharmacological evaluation of 4-[2-alkylthio-5(4)-(4-substitutedphenyl)imidazole-4(5)yl]benzenesulfonamides as selective COX-2 inhibitors. | Acta pharmacologica Sinica 20070801 |
Celebrex: new ad, with questionable claims. | Consumer reports 20070801 |
Subclinical carotid atherosclerosis in a patient with systemic lupus erythematosus. | Nature clinical practice. Rheumatology 20070801 |
Genetic susceptibility to nonsteroidal anti-inflammatory drug-related gastroduodenal bleeding: role of cytochrome P450 2C9 polymorphisms. | Gastroenterology 20070801 |
Clinical pharmacology of celecoxib, a COX-2 selective inhibitor. | Expert opinion on pharmacotherapy 20070801 |
Multivesicular liposomes bearing celecoxib-beta-cyclodextrin complex for transdermal delivery. | Drug delivery 20070801 |
Phase II testing of sunitinib: the National Cancer Institute of Canada Clinical Trials Group IND Program Trials IND.182-185. | Current oncology (Toronto, Ont.) 20070801 |
[Induction of NAG-1 gene expression in colon cancer cells by non-steroidal anti-inflammatory drugs]. | Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi 20070801 |
Estimation of proinflammatory biomarkers of skin irritation by dermal microdialysis following exposure with irritant chemicals. | Toxicology 20070731 |
The pain game. | Nature 20070726 |
Celecoxib dilates guinea-pig coronaries and rat aortic rings and amplifies NO/cGMP signaling by PDE5 inhibition. | Cardiovascular research 20070715 |
Expression of a cyclo-oxygenase-2 transgene in murine liver causes hepatitis. | Gut 20070701 |
The anti-cancer effect of COX-2 inhibitors on gastric cancer cells. | Digestive diseases and sciences 20070701 |
Cholesterol-like effects of selective cyclooxygenase inhibitors and fibrates on cellular membranes and amyloid-beta production. | Molecular pharmacology 20070701 |
Phase II study of metronomic chemotherapy for recurrent malignant gliomas in adults. | Neuro-oncology 20070701 |
Risk of myocardial infarction associated with selective COX-2 inhibitors: meta-analysis of randomised controlled trials. | Pharmacoepidemiology and drug safety 20070701 |
Tolerance to coxibs in patients with intolerance to non-steroidal anti-inflammatory drugs (NSAIDs): a systematic structured review of the literature. | Archives of dermatological research 20070701 |
Concurrent celecoxib versus placebo in patients with stage II-III non-small cell lung cancer: a randomised phase II trial. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20070701 |
Activation of p38 mitogen-activated protein kinase by celecoxib oppositely regulates survivin and gamma-H2AX in human colorectal cancer cells. | Toxicology and applied pharmacology 20070701 |
Gastrointestinal safety of cyclooxygenase-2 inhibitors: a Cochrane Collaboration systematic review. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20070701 |
Survivin is a downstream target and effector of sulindac-sensitive oncogenic Stat3 signalling in head and neck cancer. | International journal of oral and maxillofacial surgery 20070701 |
Evaluating the analgesic efficacy of administering celecoxib as a component of multimodal analgesia for outpatient anterior cruciate ligament reconstruction surgery. | Anesthesia and analgesia 20070701 |
The effect of initiating a preventive multimodal analgesic regimen on long-term patient outcomes for outpatient anterior cruciate ligament reconstruction surgery. | Anesthesia and analgesia 20070701 |
Administration of cyclooxygenase-2 inhibitor reduces joint inflammation but exacerbates osteopenia in IL-1 alpha transgenic mice due to GM-CSF overproduction. | Journal of immunology (Baltimore, Md. : 1950) 20070701 |
Up-to-date information on gastric mucosal lesions from long-term NSAID therapy in orthopedic outpatients: a study using logistic regression analysis. | Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association 20070701 |
A retrospective analysis of cardiovascular morbidity in metastatic hormone-refractory prostate cancer patients on high doses of the selective COX-2 inhibitor celecoxib. | Expert opinion on pharmacotherapy 20070701 |
[Selective COX-2 inhibitor delays experimental gastric ulcer healing by stimulating gastric acid secretion in rats]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20070701 |
[Celecoxib-induced apoptosis in acute promyelocytic leukemia cell line MR2 and its mechanism]. | Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20070701 |
Celecoxib induces apoptosis in COX-2 deficient human gastric cancer cells through Akt/GSK3beta/NAG-1 pathway. | Cancer letters 20070628 |
[Effective also in Bechterew disease]. | MMW Fortschritte der Medizin 20070621 |
Pressure application measurement (PAM): a novel behavioural technique for measuring hypersensitivity in a rat model of joint pain. | Journal of neuroscience methods 20070615 |
Celecoxib induces apoptosis by inhibiting the expression of survivin in HeLa cells. | Biochemical and biophysical research communications 20070615 |
Do proton-pump inhibitors confer additional gastrointestinal protection in patients given celecoxib? | Arthritis and rheumatism 20070615 |
A phase II trial of continuous low-dose oral cyclophosphamide and celecoxib in patients with renal cell carcinoma. | Cancer chemotherapy and pharmacology 20070601 |
The effects of COX-2 selective and non-selective NSAIDs on the initiation and progression of atherosclerosis in ApoE-/- mice. | Journal of molecular medicine (Berlin, Germany) 20070601 |
Depletion of CD4+ cells exacerbates the cutaneous response to acute and chronic UVB exposure. | The Journal of investigative dermatology 20070601 |
Characterizing early prescribers of newly marketed drugs in Canada: a population-based study. | European journal of clinical pharmacology 20070601 |
New diagnosis of hypertension among celecoxib and nonselective NSAID users: a population-based cohort study. | The Annals of pharmacotherapy 20070601 |
Chemoprevention of colorectal cancer - a new target needed? | Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland 20070601 |
Spherical crystals of celecoxib to improve solubility, dissolution rate and micromeritic properties. | Acta pharmaceutica (Zagreb, Croatia) 20070601 |
Balancing the risks and benefits of celecoxib. | The American journal of medicine 20070601 |
Induction of apoptosis by celecoxib in cell culture: an uncertain role for cyclooxygenase-2. | Cancer research 20070601 |
Preliminary development of a responder index for chronic low back pain. | The Journal of rheumatology 20070601 |
Influence of He-Ne laser therapy on the dynamics of wound healing in mice treated with anti-inflammatory drugs. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20070601 |
Effect of a selective nonsteroidal anti-inflammatory drug, celecoxib, on the reproductive function of female mice. | Journal of the Chinese Medical Association : JCMA 20070601 |
[The growth inhibitory effect of non-steroid anti-inflammatory drugs on ovarian cancer]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20070601 |
The National Cancer Institute of Canada Clinical Trials Group MAP.3 trial: an international breast cancer prevention trial. | Current oncology (Toronto, Ont.) 20070601 |
Canadian recommendations for the treatment of glioblastoma multiforme. | Current oncology (Toronto, Ont.) 20070601 |
Neuropsychiatric manifestations of depression in multiple sclerosis: neuroinflammatory, neuroendocrine, and neurotrophic mechanisms in the pathogenesis of immune-mediated depression. | Dialogues in clinical neuroscience 20070601 |
Tourette's syndrome: clinical features, pathophysiology, and therapeutic approaches. | Dialogues in clinical neuroscience 20070601 |
Hypoxia-Inducible Factor (HIF)-1 regulatory pathway and its potential for therapeutic intervention in malignancy and ischemia. | The Yale journal of biology and medicine 20070601 |
Formulation and development of floating capsules of celecoxib: in vitro and in vivo evaluation. | AAPS PharmSciTech 20070601 |
Incidence of spontaneous notifications of adverse reactions with aceclofenac, meloxicam, and rofecoxib during the first year after marketing in the United Kingdom. | Therapeutics and clinical risk management 20070601 |
Tramadol extended-release in the management of chronic pain. | Therapeutics and clinical risk management 20070601 |
A review of the role of capecitabine in the treatment of colorectal cancer. | Therapeutics and clinical risk management 20070601 |
Current aproach to cancer pain management: Availability and implications of different treatment options. | Therapeutics and clinical risk management 20070601 |
Targeting inhibition of COX-2: a review of patents, 2002-2006. | Recent patents on inflammation & allergy drug discovery 20070601 |
Naproxen and celecoxib do not prevent AD in early results from a randomized controlled trial. | Neurology 20070522 |
A phase II study of biweekly dose-intensified oral capecitabine plus irinotecan (bXELIRI) for patients with advanced or metastatic gastric cancer. | British journal of cancer 20070521 |
Small bowel mucosal injury is reduced in healthy subjects treated with celecoxib compared with ibuprofen plus omeprazole, as assessed by video capsule endoscopy. | Alimentary pharmacology & therapeutics 20070515 |
Enhancement of docetaxel-induced cytotoxicity by blocking epidermal growth factor receptor and cyclooxygenase-2 pathways in squamous cell carcinoma of the head and neck. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070515 |
P-glycoprotein mediates celecoxib-induced apoptosis in multiple drug-resistant cell lines. | Cancer research 20070515 |
Combination of a cyclo-oxygenase-2 inhibitor and a proton-pump inhibitor for prevention of recurrent ulcer bleeding in patients at very high risk: a double-blind, randomised trial. | Lancet (London, England) 20070512 |
[Cardiovascular and gastrointestinal risks associated with selective and non-selective NSAIDs]. | Nederlands tijdschrift voor geneeskunde 20070512 |
Involvement of up-regulation of PUMA in non-steroidal anti-inflammatory drug-induced apoptosis. | Biochemical and biophysical research communications 20070511 |
Celecoxib inhibits Na+ currents in rat dorsal root ganglion neurons. | Brain research 20070507 |
A preclinical evaluation of pemetrexed and irinotecan combination as second-line chemotherapy in pancreatic cancer. | British journal of cancer 20070507 |
Association between nonnaproxen NSAIDs, COX-2 inhibitors and hospitalization for acute myocardial infarction among the elderly: a retrospective cohort study. | Pharmacoepidemiology and drug safety 20070501 |
The CADEUS study: methods and logistics. | Pharmacoepidemiology and drug safety 20070501 |
Use of calcined Mg-Al-hydrotalcite to enhance the stability of celecoxib in the amorphous form. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20070501 |
Determination of lefucoxib in rat plasma, urine, and feces by high-performance liquid chromatography with fluorescence detection: application in pharmacokinetic studies. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070501 |
Celecoxib inhibits the expression of survivin via the suppression of promoter activity in human colon cancer cells. | Biochemical pharmacology 20070501 |
R-Etodolac decreases beta-catenin levels along with survival and proliferation of hepatoma cells. | Journal of hepatology 20070501 |
Increased expression of cyclooxygenase-2 correlates with resistance to radiation in human prostate adenocarcinoma cells. | The Journal of urology 20070501 |
A shot in the dark: failing to recognize the link between physical and mental illness. | Journal of general internal medicine 20070501 |
Celecoxib decreases fatty acid synthase expression via down-regulation of c-Jun N-terminal kinase-1. | Experimental biology and medicine (Maywood, N.J.) 20070501 |
The role of the Back Rx exercise program in diskogenic low back pain: a prospective randomized trial. | Archives of physical medicine and rehabilitation 20070501 |
Effect of short-term postoperative celecoxib administration on patient outcome after outpatient laparoscopic surgery. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20070501 |
Simultaneous measurements of K+ and calcein release from liposomes and the determination of pore size formed in a membrane. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20070501 |
No proof of cross-reactivity between celecoxib and antibiotic sulfonamides. | Internal medicine journal 20070501 |
Assessment of comparative pain relief and tolerability of SKI306X compared with celecoxib in patients with rheumatoid arthritis: a 6-week, multicenter, randomized, double-blind, double-dummy, phase III, noninferiority clinical trial. | Clinical therapeutics 20070501 |
JP-8 jet fuel exposure rapidly induces high levels of IL-10 and PGE2 secretion and is correlated with loss of immune function. | Toxicology and industrial health 20070501 |
Risk of congestive heart failure with nonsteroidal antiinflammatory drugs and selective Cyclooxygenase 2 inhibitors: a class effect? | Arthritis and rheumatism 20070415 |
Celecoxib toxicity is cell cycle phase specific. | Cancer research 20070415 |
Celecoxib attenuates 5-fluorouracil-induced apoptosis in HCT-15 and HT-29 human colon cancer cells. | World journal of gastroenterology 20070407 |
[Further definition of the role of COX-2 inhibitors and NSAIDs in patients with nociceptive pain]. | Nederlands tijdschrift voor geneeskunde 20070407 |
NO-donor COX-2 inhibitors. New nitrooxy-substituted 1,5-diarylimidazoles endowed with COX-2 inhibitory and vasodilator properties. | Journal of medicinal chemistry 20070405 |
Lipoperoxidation and cyclooxygenases 1 and 2 inhibitory compounds from Iryanthera juruensis. | Journal of agricultural and food chemistry 20070404 |
Secondary chemoprevention of Barrett's esophagus with celecoxib: results of a randomized trial. | Journal of the National Cancer Institute 20070404 |
Quantitative assessment of the gastrointestinal and cardiovascular risk-benefit of celecoxib compared to individual NSAIDs at the population level. | Pharmacoepidemiology and drug safety 20070401 |
A phase I/II trial of celecoxib with chemotherapy and radiotherapy in the treatment of patients with locally advanced oesophageal cancer. | Investigational new drugs 20070401 |
Characterizing new users of NSAIDs before and after rofecoxib withdrawal. | British journal of clinical pharmacology 20070401 |
Celecoxib and CVS risk--lessons from the APC and PreSAP studies. | Rheumatology (Oxford, England) 20070401 |
Structural pathology in a rodent model of osteoarthritis is associated with neuropathic pain: increased expression of ATF-3 and pharmacological characterisation. | Pain 20070401 |
Surface phospholipids in gastric injury and protection when a selective cyclooxygenase-2 inhibitor (Coxib) is used in combination with aspirin. | British journal of pharmacology 20070401 |
MR monitoring of cyclooxygenase-2 inhibition of angiogenesis in a human breast cancer model in rats. | Radiology 20070401 |
Failure of apoptosis and activation on NFkappaB by celecoxib and aspirin in lung cancer cell lines. | Oncology reports 20070401 |
Combinatorial prevention of carcinogenic risk in a model for familial colon cancer. | Oncology reports 20070401 |
Down-regulation of PGE2 by physiologic levels of celecoxib is not sufficient to induce apoptosis or inhibit cell proliferation in human colon carcinoma cell lines. | Digestive diseases and sciences 20070401 |
In vivo effects of amtolmetin guacyl on lipid peroxidation and antioxidant defence systems. Comparison with non-selective and COX-2 selective NSAIDs. | Autonomic & autacoid pharmacology 20070401 |
A reduction of cyclooxygenase 2 gene dosage counters the ovarian morphological aging and tumor phenotype in Wv mice. | The American journal of pathology 20070401 |
Angiogenic inhibition reduces germinal matrix hemorrhage. | Nature medicine 20070401 |
Phase II study of gefitinib, an epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI), and celecoxib, a cyclooxygenase-2 (COX-2) inhibitor, in patients with platinum refractory non-small cell lung cancer (NSCLC). | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20070401 |
[Effects of selective cyclooxygenase-2 inhibitor on proliferation and apoptosis of human bladder cancer cell line T24]. | Ai zheng = Aizheng = Chinese journal of cancer 20070401 |
Calcium-activated endoplasmic reticulum stress as a major component of tumor cell death induced by 2,5-dimethyl-celecoxib, a non-coxib analogue of celecoxib. | Molecular cancer therapeutics 20070401 |
The effect of 2 Hz and 100 Hz electrical stimulation of acupoint on ankle sprain in rats. | Journal of Korean medical science 20070401 |
Cyclooxygenase-2 induction by arsenite through the IKKbeta/NFkappaB pathway exerts an antiapoptotic effect in mouse epidermal Cl41 cells. | Environmental health perspectives 20070401 |
Effect of low-level laser therapy on hemorrhagic lesions induced by immune complex in rat lungs. | Photomedicine and laser surgery 20070401 |
Letter by Cen regarding article, 'Effect of celecoxib on cardiovascular events and blood pressure in two trials for the prevention of colorectal adenomas'. | Circulation 20070327 |
Sulfonation of 17beta-estradiol and inhibition of sulfotransferase activity by polychlorobiphenylols and celecoxib in channel catfish, Ictalurus punctatus. | Aquatic toxicology (Amsterdam, Netherlands) 20070310 |
Efficacy and safety of etoricoxib 30 mg and celecoxib 200 mg in the treatment of osteoarthritis in two identically designed, randomized, placebo-controlled, non-inferiority studies. | Rheumatology (Oxford, England) 20070301 |
Adjusted indirect comparison of celecoxib versus rofecoxib on cardiovascular risk. | Rheumatology international 20070301 |
Up-regulation of 150-kDa oxygen-regulated protein by celecoxib in human gastric carcinoma cells. | Molecular pharmacology 20070301 |
Inflammation induces mitochondrial dysfunction and dopaminergic neurodegeneration in the nigrostriatal system. | Journal of neurochemistry 20070301 |
Risks and benefits of COX-2 inhibitors vs non-selective NSAIDs: does their cardiovascular risk exceed their gastrointestinal benefit? A retrospective cohort study. | Rheumatology (Oxford, England) 20070301 |
Design, synthesis, and biological evaluation of substituted 2-alkylthio-1,5-diarylimidazoles as selective COX-2 inhibitors. | Bioorganic & medicinal chemistry 20070301 |
Enhancement of glioblastoma radioresponse by a selective COX-2 inhibitor celecoxib: inhibition of tumor angiogenesis with extensive tumor necrosis. | International journal of radiation oncology, biology, physics 20070301 |
Cyclooxygenase-2 inhibition increases gastric tone and delays gastric emptying in rats. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20070301 |
When is a neoplasm not a neoplasm? When it is a desmoid. | Journal of surgical oncology 20070301 |
Dose and time-dependent effects of cyclooxygenase-2 inhibition on fracture-healing. | The Journal of bone and joint surgery. American volume 20070301 |
Combined inhibitory effects of green tea polyphenols and selective cyclooxygenase-2 inhibitors on the growth of human prostate cancer cells both in vitro and in vivo. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070301 |
Does the consumption of green tea reduce the risk of lung cancer among smokers? | Evidence-based complementary and alternative medicine : eCAM 20070301 |
The selective cyclooxygenase-2 inhibitor celecoxib reduces bone resorption, but not bone formation, in ovariectomized mice in vivo. | The Tohoku journal of experimental medicine 20070301 |
Short-term efficacy of rofecoxib and diclofenac in acute shoulder pain: a placebo-controlled randomized trial. | PLoS clinical trials 20070301 |
Dynamic simulations on the arachidonic acid metabolic network. | PLoS computational biology 20070301 |
Adenoviral pneumonia during etanercept treatment in a patient with rheumatoid arthritis. | The Korean journal of internal medicine 20070301 |
[Role of cyclooxygenase-2 in pulmonary microcirculation disorder in rats with acute pancreatitis]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20070301 |
Eosinophilic fasciitis in a 57-year-old Japanese-American woman. | Hawaii medical journal 20070301 |
Selective inhibition of prostacyclin synthase activity by rofecoxib. | Journal of cellular and molecular medicine 20070301 |
Expression of cyclooxygenase-2 in osteosarcoma of bone. | Applied immunohistochemistry & molecular morphology : AIMM 20070301 |
A randomized, double-blind, celecoxib- and placebo-controlled study of the effectiveness of CS-706 in acute postoperative dental pain. | Clinical therapeutics 20070301 |
Acetaminophen is as good as celecoxib for degenerative joint disease. | The Journal of family practice 20070301 |
Determination of the optimal combination chemotherapy regimen for treatment of platinum-resistant ovarian cancer in nude mouse model. | Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners 20070301 |
[Antitumor effects of specific cyclooxygenase inhibitors combined with chemotherapeutic agents on gastric cancer cells in vitro]. | Zhonghua zhong liu za zhi [Chinese journal of oncology] 20070301 |
Motexafin gadolinium injection for the treatment of brain metastases in patients with non-small cell lung cancer. | International journal of nanomedicine 20070301 |
Activity and potential role of licofelone in the management of osteoarthritis. | Clinical interventions in aging 20070301 |
3-Phosphoinositide-dependent protein kinase-1/Akt signalling and inhibition in a canine prostate carcinoma cell line. | Veterinary and comparative oncology 20070301 |
Studies in 3,4-diaryl-1,2,5-oxadiazoles and their N-oxides: search for better COX-2 inhibitors. | Acta pharmaceutica (Zagreb, Croatia) 20070301 |
Physicochemical characterization and in vitro dissolution behaviour of celecoxib-beta-cyclodextrin inclusion complexes. | Acta pharmaceutica (Zagreb, Croatia) 20070301 |
Cyclooxygenase-2 inhibition: effects on tumour growth, cell cycling and lymphangiogenesis in a xenograft model of breast cancer. | British journal of cancer 20070226 |
5-Heteroatom substituted pyrazoles as canine COX-2 inhibitors. Part III: molecular modeling studies on binding contribution of 1-(5-methylsulfonyl)pyrid-2-yl and 4-nitrile. | Bioorganic & medicinal chemistry letters 20070215 |
A novel copper complex of 3-benzoyl-alpha methyl benzene acetic acid with antitumor activity mediated via cyclooxygenase pathway. | International journal of cancer 20070215 |
Synthesis and biological evaluation of some 5-ethoxycarbonyl-6-isopropylamino-4-(substitutedphenyl)aminopyrimidines as potent analgesic and anti-inflammatory agents. | Bioorganic & medicinal chemistry letters 20070215 |
Chronic celecoxib users more often show regression of gastric intestinal metaplasia after Helicobacter pylori eradication. | Alimentary pharmacology & therapeutics 20070215 |
Cyclooxygenase inhibitors and cardiovascular risk. | JAMA 20070214 |
Targeting EGF-receptor-signalling in squamous cell carcinomas of the head and neck. | British journal of cancer 20070212 |
Additive interaction of intraperitoneal dexmedetomidine and topical nimesulide, celecoxib, and DFU for antinociception. | European journal of pharmacology 20070205 |
Hospitalization for gastrointestinal bleeding associated with non-steroidal anti-inflammatory drugs among elderly patients using low-dose aspirin: a retrospective cohort study. | Rheumatology (Oxford, England) 20070201 |
The coronary risk of cyclo-oxygenase-2 inhibitors in patients with a previous myocardial infarction. | Heart (British Cardiac Society) 20070201 |
Revised statistical motor unit number estimation in the Celecoxib/ALS trial. | Muscle & nerve 20070201 |
Risk and risk reduction involving arginine intake and meat consumption in colorectal tumorigenesis and survival. | International journal of cancer 20070201 |
Elevated expression of cyclooxygenase-2 is a negative prognostic factor for overall survival in intrahepatic cholangiocarcinoma. | Virchows Archiv : an international journal of pathology 20070201 |
Celecoxib inhibits meningioma tumor growth in a mouse xenograft model. | Cancer 20070201 |
Chemoprevention by cyclooxygenase-2 inhibition reduces immature myeloid suppressor cell expansion. | International immunopharmacology 20070201 |
Inhibition of cyclooxygenase-2 activity by celecoxib does not lead to radiosensitization of human prostate cancer cells in vitro. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20070201 |
Celecoxib as adjunctive therapy in schizophrenia: a double-blind, randomized and placebo-controlled trial. | Schizophrenia research 20070201 |
Effect of celecoxib on E-cadherin, VEGF, Microvessel density and apoptosis in gastric cancer. | Cancer biology & therapy 20070201 |
Effect of different cyclooxygenase inhibitors on gastric adaptive cytoprotection induced by 20% ethanol. | Digestive diseases and sciences 20070201 |
Effects of cyclooxygenase-2 inhibitor on glucagon-induced delayed gastric emptying and gastric dysrhythmia in dogs. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20070201 |
Racial/ethnic differences in the use of complementary and alternative medicine in patients with arthritis. | Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20070201 |
Celecoxib and mucosal protection: translation from an animal model to a phase I clinical trial of celecoxib, irinotecan, and 5-fluorouracil. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070201 |
Celecoxib prevents neuroblastoma tumor development and potentiates the effect of chemotherapeutic drugs in vitro and in vivo. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070201 |
RE: 'Transfer of celecoxib into human milk'. | Journal of human lactation : official journal of International Lactation Consultant Association 20070201 |
The adenoma prevention with celecoxib and prevention of colorectal sporadic adenomatous polyps trials: stepping stones to progress. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20070201 |
COX-2 inhibition: a possible role in the management of prostate cancer? | Journal of chemotherapy (Florence, Italy) 20070201 |
The coxibs and traditional nonsteroidal anti-inflammatory drugs: a current perspective on cardiovascular risks. | The Canadian journal of cardiology 20070201 |
Celecoxib versus ibuprofen in the prevention of heterotopic ossification following total hip replacement: a prospective randomised trial. | The Journal of bone and joint surgery. British volume 20070201 |
Chemopreventive effect of celecoxib in gastric cancer. | Inflammopharmacology 20070201 |
NSAIDs modulate CDKN2A, TP53, and DNA content risk for progression to esophageal adenocarcinoma. | PLoS medicine 20070201 |
12 things you should know about pain relievers. A dozen take-home messages about the pills that take the hurt away. | Harvard health letter 20070201 |
Evaluation of the cancer chemopreventive efficacy of rice bran in genetic mouse models of breast, prostate and intestinal carcinogenesis. | British journal of cancer 20070129 |
Cyclooxygenase-2 inhibition increases mortality, enhances left ventricular remodeling, and impairs systolic function after myocardial infarction in the pig. | Circulation 20070123 |
Cyclooxygenase inhibition and adverse remodeling during healing after myocardial infarction. | Circulation 20070123 |
Combined neuroprotective effects of celecoxib and memantine in experimental intracerebral hemorrhage. | Neuroscience letters 20070116 |
Synthesis and biological evaluation of quinoline salicylic acids as P-selectin antagonists. | Journal of medicinal chemistry 20070111 |
Mucosal acid causes gastric mucosal microcirculatory disturbance in nonsteroidal anti-inflammatory drug-treated rats. | European journal of pharmacology 20070105 |
Thalidomide and celecoxib as potential modulators of irinotecan's activity in cancer patients. | Cancer chemotherapy and pharmacology 20070101 |
Celecoxib compared with sustained-release paracetamol for osteoarthritis: a series of n-of-1 trials. | Rheumatology (Oxford, England) 20070101 |
A prospective randomised multicentre study comparing continuous and intermittent treatment with celecoxib in patients with osteoarthritis of the knee or hip. | Annals of the rheumatic diseases 20070101 |
Phase II study of an optimized 5-fluorouracil-oxaliplatin strategy (OPTIMOX2) with celecoxib in metastatic colorectal cancer: a GERCOR study. | Annals of oncology : official journal of the European Society for Medical Oncology 20070101 |
Inflammation-induced reduction of spontaneous activity by adjuvant: A novel model to study the effect of analgesics in rats. | The Journal of pharmacology and experimental therapeutics 20070101 |
A prospective phase I-II trial of the cyclooxygenase-2 inhibitor celecoxib in patients with carcinoma of the cervix with biomarker assessment of the tumor microenvironment. | International journal of radiation oncology, biology, physics 20070101 |
Long-term efficacy and safety of celecoxib in Alzheimer's disease. | Dementia and geriatric cognitive disorders 20070101 |
A Phase II study of acute toxicity for Celebrex (celecoxib) and chemoradiation in patients with locally advanced cervical cancer: primary endpoint analysis of RTOG 0128. | International journal of radiation oncology, biology, physics 20070101 |
Celecoxib enhances doxorubicin-induced cytotoxicity in MDA-MB231 cells by NF-kappaB-mediated increase of intracellular doxorubicin accumulation. | European journal of cancer (Oxford, England : 1990) 20070101 |
Sulfonamide allergy without cross-reactivity to celecoxib. | Allergy 20070101 |
Pharmacodynamic of cyclooxygenase inhibitors in humans. | Prostaglandins & other lipid mediators 20070101 |
GADD153 mediates celecoxib-induced apoptosis in cervical cancer cells. | Carcinogenesis 20070101 |
FDA advisers endorse Celebrex for juvenile rheumatoid arthritis: lack of studies in children raises safety concerns. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20070101 |
Risk of cardiovascular events in patients receiving celecoxib: a meta-analysis of randomized clinical trials. | The American journal of cardiology 20070101 |
Potential antioxidant activity of celecoxib and amtolmetin guacyl: in vitro studies. | Autonomic & autacoid pharmacology 20070101 |
Radiosensitization by 2-benzoyl-3-phenyl-6,7-dichloroquinoxaline 1,4-dioxide under oxia and hypoxia in human colon cancer cells. | Radiation oncology (London, England) 20070101 |
Review: risk for cardiovascular events is increased with rofecoxib, diclofenac, and indomethacin but not celecoxib. | ACP journal club 20070101 |
Modification of the crystal habit of celecoxib for improved processability. | The Journal of pharmacy and pharmacology 20070101 |
Intra-articular injection of a nutritive mixture solution protects articular cartilage from osteoarthritic progression induced by anterior cruciate ligament transection in mature rabbits: a randomized controlled trial. | Arthritis research & therapy 20070101 |
The efficacy of oral nonsteroidal anti-inflammatory medication (NSAID) in the treatment of plantar fasciitis: a randomized, prospective, placebo-controlled study. | Foot & ankle international 20070101 |
Early onset pauciarticular arthritis is the major risk factor for naproxen-induced pseudoporphyria in juvenile idiopathic arthritis. | Arthritis research & therapy 20070101 |
Evaluation of the patient acceptable symptom state in a pooled analysis of two multicentre, randomised, double-blind, placebo-controlled studies evaluating lumiracoxib and celecoxib in patients with osteoarthritis. | Arthritis research & therapy 20070101 |
Effects of specific inhibition of cyclooxygenease-2 on kidney in bilateral adrenalectomized rats. | International urology and nephrology 20070101 |
Antinociceptive efficacy of lacosamide in the monosodium iodoacetate rat model for osteoarthritis pain. | Arthritis research & therapy 20070101 |
[COX-2 and HO-1 are involved in the delayed preconditioning elicited by bradykinin in rat hearts]. | Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20070101 |
Thromboembolic cardiovascular risk among arthritis patients using cyclooxygenase-2-selective inhibitor or nonselective cyclooxygenase inhibitor nonsteroidal anti-inflammatory drugs. | American journal of therapeutics 20070101 |
COX-2 inhibitors celecoxib and parecoxib: valuable options for postoperative pain management. | Current topics in medicinal chemistry 20070101 |
Unilateral conjunctival chemosis as a unique symptom of nonsteroidal anti-inflammatory drug intolerance. | Journal of investigational allergology & clinical immunology 20070101 |
Handgrip performance in relation to self-perceived fatigue, physical functioning and circulating IL-6 in elderly persons without inflammation. | BMC geriatrics 20070101 |
Use of celecoxib immediately post marketing in Canada: acute or chronic pain? | The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20070101 |
An exploratory study of primary care physician decision making regarding total joint arthroplasty. | Journal of general internal medicine 20070101 |
Cell culture model for colon cancer prevention and therapy: an alternative approach to animal experimentation. | ALTEX 20070101 |
Effects of celecoxib on migration, proliferation and collagen expression of tendon cells. | Connective tissue research 20070101 |
Tyrosine kinase inhibitor SU6668 represses chondrosarcoma growth via antiangiogenesis in vivo. | BMC cancer 20070101 |
Evidence for placebo effects on physical but not on biochemical outcome parameters: a review of clinical trials. | BMC medicine 20070101 |
Effect of celecoxib on fasciocutaneous flap survival and revascularization. | Archives of facial plastic surgery 20070101 |
Maintenance treatment with esomeprazole following initial relief of non-steroidal anti-inflammatory drug-associated upper gastrointestinal symptoms: the NASA2 and SPACE2 studies. | Arthritis research & therapy 20070101 |
Apoptotic effect of celecoxib dependent upon p53 status in human ovarian cancer cells. | Annals of the New York Academy of Sciences 20070101 |
The cyclooxygenase-2 selective inhibitor celecoxib suppresses proliferation and invasiveness in the human oral squamous carcinoma. | Annals of the New York Academy of Sciences 20070101 |
[The best of clinical pharmacology in 2006]. | Archives des maladies du coeur et des vaisseaux 20070101 |
Effects of celecoxib on human chondrocytes--enhanced production of chemokines. | Clinical and experimental rheumatology 20070101 |
Decisions by regulatory agencies: are they evidence-based? | Trials 20070101 |
Celecoxib prevents juxta-articular osteopenia and growth plate destruction adjacent to inflamed joints in rats with collagen-induced arthritis. | Modern rheumatology 20070101 |
Polymeric nanoparticle-encapsulated curcumin ('nanocurcumin'): a novel strategy for human cancer therapy. | Journal of nanobiotechnology 20070101 |
Protective role of fish oil (Maxepa) on early events of rat mammary carcinogenesis by modulation of DNA-protein crosslinks, cell proliferation and p53 expression. | Cancer cell international 20070101 |
Inhibition of Akt pathways in the treatment of prostate cancer. | Prostate cancer and prostatic diseases 20070101 |
Development and evaluation of a gastroretentive drug delivery system for the low-absorption-window drug celecoxib. | PDA journal of pharmaceutical science and technology 20070101 |
Celecoxib:nicotinamide dissociation: using excipients to capture the cocrystal's potential. | Molecular pharmaceutics 20070101 |
Dual carbonic anhydrase--cyclooxygenase-2 inhibitors. | Current topics in medicinal chemistry 20070101 |
Effect of celecoxib on cyclooxygenase-2 expression and possible variants in a patient with Barrett's esophagus. | Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20070101 |
Cyclooxygenase 2 expression in pterygium. | Molecular vision 20070101 |
Proton-pump inhibitors are associated with a reduced risk for bleeding and perforated gastroduodenal ulcers attributable to non-steroidal anti-inflammatory drugs: a nested case-control study. | Arthritis research & therapy 20070101 |
Generic drug policy in Australia: a community pharmacy perspective. | Australia and New Zealand health policy 20070101 |
Simultaneous inhibition of COX-2 and 5-LOX activities augments growth arrest and death of premalignant and malignant human lung cell lines. | Journal of experimental therapeutics & oncology 20070101 |
Arthritis and pain. Future targets to control osteoarthritis pain. | Arthritis research & therapy 20070101 |
Prevention of posterior capsular opacification through cyclooxygenase-2 inhibition. | Molecular vision 20070101 |
Reduced risk of human lung cancer by selective cyclooxygenase 2 (COX-2) blockade: results of a case control study. | International journal of biological sciences 20070101 |
Celebrex approved for juvenile arthritis. | FDA consumer 20070101 |
Bayesian confidence propagation neural network. | Drug safety 20070101 |
An economic model of long-term use of celecoxib in patients with osteoarthritis. | BMC gastroenterology 20070101 |
The flavonoid luteolin worsens chemical-induced colitis in NF-kappaB(EGFP) transgenic mice through blockade of NF-kappaB-dependent protective molecules. | PloS one 20070101 |
Cyclooxygenase-2 (cox-2) and the inflammogenesis of cancer. | Sub-cellular biochemistry 20070101 |
Strategies for colon cancer prevention: combination of chemopreventive agents. | Sub-cellular biochemistry 20070101 |
Adenovirus type 5 E1A-induced apoptosis in COX-2-overexpressing breast cancer cells. | Breast cancer research : BCR 20070101 |
Findings in patients with chronic intestinal dysmotility investigated by capsule endoscopy. | BMC gastroenterology 20070101 |
Inflammation and breast cancer. Cyclooxygenase/prostaglandin signaling and breast cancer. | Breast cancer research : BCR 20070101 |
The cytotoxicity of celecoxib towards cardiac myocytes is cyclooxygenase-2 independent. | Cardiovascular toxicology 20070101 |
Chronic administration of R-flurbiprofen attenuates learning impairments in transgenic amyloid precursor protein mice. | BMC neuroscience 20070101 |
Anti-inflammatory and side effects of cyclooxygenase inhibitors. | Pharmacological reports : PR 20070101 |
Glucosamine and chondroitin sulfate as therapeutic agents for knee and hip osteoarthritis. | Drugs & aging 20070101 |
Safety of celecoxib in patients with cutaneous reactions due to ASA-NSAIDs intolerance. | Allergologia et immunopathologia 20070101 |
Medical treatment and other combination regimens. | Tumori 20070101 |
Cyclo-oxygenase-2 selective inhibitors and nonsteroidal anti-inflammatory drugs: balancing gastrointestinal and cardiovascular risk. | BMC musculoskeletal disorders 20070101 |
Exploring effects of different nonsteroidal antiinflammatory drugs on lipid peroxidation. Part II. 4-HNE profile. | Acta poloniae pharmaceutica 20070101 |
Celecoxib increased expression of 14-3-3sigma and induced apoptosis of glioma cells. | Anticancer research 20070101 |
Atypical antipsychotics in bipolar disorder: systematic review of randomised trials. | BMC psychiatry 20070101 |
Effectiveness of compression stockings to prevent the post-thrombotic syndrome (the SOX Trial and Bio-SOX biomarker substudy): a randomized controlled trial. | BMC cardiovascular disorders 20070101 |
Effect of the COX-2 inhibitor celecoxib on behavioural and immune changes in an olfactory bulbectomised rat model of depression. | Neuroimmunomodulation 20070101 |
Anithrombotic prevention in vascular disease: bases for a new strategy in antithrombotic therapy. | Thrombosis journal 20070101 |
Celecoxib combined with esomeprazole prevented recurrent ulcer bleeding in patients with previous NSAID-induced ulcer bleeding. | ACP journal club 20070101 |
Enhanced retention of celecoxib-loaded solid lipid nanoparticles after intra-articular administration. | Drugs in R&D 20070101 |
The tell-tale heart: population-based surveillance reveals an association of rofecoxib and celecoxib with myocardial infarction. | PloS one 20070101 |
Effect of hydroalcoholic extract of Zingiber officinalis rhizomes on LPS-induced rat airway hyperreactivity and lung inflammation. | Prostaglandins, leukotrienes, and essential fatty acids 20070101 |
[Acute pancreatitis after treatment by celecoxib]. | Gastroenterologie clinique et biologique 20070101 |
Effects of eicosapentaenoic and docosahexaenoic n-3 fatty acids from fish oil and preferential Cox-2 inhibition on systemic syndromes in patients with advanced lung cancer. | Nutrition and cancer 20070101 |
Chemopreventive effects of nonsteroidal anti-inflammatory drugs in the membrane lipid composition and fluidity parameters of the 1,2-dimethylhydrazine-induced colon carcinogenesis in rats. | Drug and chemical toxicology 20070101 |
Single dose oral lumiracoxib for postoperative pain. | The Cochrane database of systematic reviews 20070101 |
Inflammatory response and meningioma tumorigenesis and the effect of cyclooxygenase-2 inhibitors. | Neurosurgical focus 20070101 |
Intestinal toxicity of non-steroidal anti-inflammatory drugs with differential cyclooxygenase inhibition selectivity. | Nutricion hospitalaria 20070101 |
Comparison of glucosamine sulfate and a polyherbal supplement for the relief of osteoarthritis of the knee: a randomized controlled trial [ISRCTN25438351]. | BMC complementary and alternative medicine 20070101 |
Celecoxib: a review of its use in the management of arthritis and acute pain. | Drugs 20070101 |
Cells of the synovium in rheumatoid arthritis. Chondrocytes. | Arthritis research & therapy 20070101 |
Effects of acetylsalicylic acid and celecoxib on the N-nitrosodiethylamine induced carcinogenesis in rat liver and esophagus. | Bulletin of experimental biology and medicine 20070101 |
Transcriptional profiling of non-small cell lung cancer cells with activating EGFR somatic mutations. | PloS one 20070101 |
Mechanical properties during healing of Achilles tendon ruptures to predict final outcome: a pilot Roentgen stereophotogrammetric analysis in 10 patients. | BMC musculoskeletal disorders 20070101 |
The effects of a cyclooxygenase-2 (COX-2) expression and inhibition on human uveal melanoma cell proliferation and macrophage nitric oxide production. | Journal of carcinogenesis 20070101 |
Preparation and physicochemical and preclinical evaluations of recrystallized celecoxib. | PDA journal of pharmaceutical science and technology 20070101 |
Bortezomib in combination with celecoxib in patients with advanced solid tumors: a phase I trial. | BMC cancer 20070101 |
Apoptosis is not the major death mechanism induced by celecoxib on rheumatoid arthritis synovial fibroblasts. | Arthritis research & therapy 20070101 |
Cyclooxygenase inhibition lowers prostaglandin E2 release from articular cartilage and reduces apoptosis but not proteoglycan degradation following an impact load in vitro. | Arthritis research & therapy 20070101 |
Adverse drug interactions involving common prescription and over-the-counter analgesic agents. | Clinical therapeutics 20070101 |
Analgesic efficacy of celecoxib in postoperative oral surgery pain: a single-dose, two-center, randomized, double-blind, active- and placebo-controlled study. | Clinical therapeutics 20070101 |
Cells of the synovium in rheumatoid arthritis. Synovial fibroblasts. | Arthritis research & therapy 20070101 |
Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy. | Experimental diabetes research 20070101 |
[Reactivity and communication of Health Authorities toward health professionals: a public health priority]. | Therapie 20070101 |
The immune response is involved in atherosclerotic plaque calcification: could the RANKL/RANK/OPG system be a marker of plaque instability? | Clinical & developmental immunology 20070101 |
Comparison of antinociceptive efficacy and gastroprotection between celecoxib and diclofenac plus misoprostol in rats. | Proceedings of the Western Pharmacology Society 20070101 |
[Articular cartilage in osteoarthritic patients: effects of diclofenac, celecoxib and glucosamine sulfate on inflammatory markers]. | Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina) 20070101 |
Cyclooxygenase-2 (COX-2) in carcinogenesis and selective COX-2 inhibitors for chemoprevention in gastrointestinal cancers. | Journal of gastrointestinal cancer 20070101 |
Chemopreventive effects of nonsteroidal anti-inflammatory drugs on 1,2-dimethylhydrazine-induced colon carcinogenesis in rats. | Toxicology mechanisms and methods 20070101 |
Alterations in the lipid profile and membrane dynamics of rat intestinal brush border membrane induced by different classes of nonsteroidal anti-inflammatory drugs. | Toxicology mechanisms and methods 20070101 |
Nonsteroidal anti-inflammatory drug hypersensitivity in preschool children. | Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20070101 |
Clinical management of adult patients with a history of nonsteroidal anti-inflammatory drug-induced urticaria/angioedema: update. | Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology 20070101 |
Statistical fallacies in orthopedic research. | Indian journal of orthopaedics 20070101 |
Lumiracoxib: the evidence of its clinical impact on the treatment of osteoarthritis. | Core evidence 20070101 |
Adalimumab in ankylosing spondylitis: an evidence-based review of its place in therapy. | Core evidence 20070101 |
Microscopic modes and free energies of 3-phosphoinositide-dependent kinase-1 (PDK1) binding with celecoxib and other inhibitors. | The journal of physical chemistry. B 20061228 |
Nitric oxide deficiency promotes vascular side effects of cyclooxygenase inhibitors. | Blood 20061215 |
Intestinal effects of nonselective and selective cyclooxygenase inhibitors in the rat. | European journal of pharmacology 20061215 |
Stability of the patient acceptable symptomatic state over time in outcome criteria in ankylosing spondylitis. | Arthritis and rheumatism 20061215 |
[The inhibitive effects of celecoxib combined with octreotide on the metastasis of human gastric cancer in vivo]. | Zhonghua yi xue za zhi 20061212 |
Effects of non-steroidal anti-inflammatory drugs on cell proliferation and death in cultured epiphyseal-articular chondrocytes of fetal rats. | Toxicology 20061207 |
Risk of upper gastrointestinal ulcer bleeding associated with selective cyclo-oxygenase-2 inhibitors, traditional non-aspirin non-steroidal anti-inflammatory drugs, aspirin and combinations. | Gut 20061201 |
Prostaglandin E2 is a potent inhibitor of epithelial-to-mesenchymal transition: interaction with hepatocyte growth factor. | American journal of physiology. Renal physiology 20061201 |
Synthesis and biological evaluation of a novel class of rofecoxib analogues as dual inhibitors of cyclooxygenases (COXs) and lipoxygenases (LOXs). | Bioorganic & medicinal chemistry 20061201 |
Design, synthesis, and biological evaluation of (E)-3-(4-methanesulfonylphenyl)-2-(aryl)acrylic acids as dual inhibitors of cyclooxygenases and lipoxygenases. | Bioorganic & medicinal chemistry 20061201 |
Comparison of antinociceptive actions of standard analgesics in attenuating capsaicin and nerve-injury-induced mechanical hypersensitivity. | Neuroscience 20061201 |
Low-grade systemic inflammation causes endothelial dysfunction in patients with Hashimoto's thyroiditis. | The Journal of clinical endocrinology and metabolism 20061201 |
Temozolomide in combination with celecoxib in patients with advanced melanoma. A phase II study of the Hellenic Cooperative Oncology Group. | Annals of oncology : official journal of the European Society for Medical Oncology 20061201 |
Coupled atomic charge selectivity for optimal ligand-charge distributions at protein binding sites. | Journal of computational chemistry 20061201 |
The impact of NSAID or COX-2 inhibitor use on the initiation of antihypertensive therapy. | Pharmacoepidemiology and drug safety 20061201 |
Use of cyclo-oxygenase 2 inhibitors (COX-2) and prescription non-steroidal anti-inflammatory drugs (NSAIDS) in UK and USA populations. Implications for COX-2 cardiovascular profile. | Pharmacoepidemiology and drug safety 20061201 |
Cyclooxygenase-2 inhibition attenuates antibody responses against human papillomavirus-like particles. | Journal of immunology (Baltimore, Md. : 1950) 20061201 |
Safety and efficacy of short-term celecoxib before elective percutaneous coronary intervention for stable angina pectoris. | The American journal of cardiology 20061201 |
Platelet-derived growth factor receptor-beta in Gorham's disease. | Nature clinical practice. Oncology 20061201 |
Cellular FLICE-inhibitory protein down-regulation contributes to celecoxib-induced apoptosis in human lung cancer cells. | Cancer research 20061201 |
Conformal radiotherapy of the dominant liver metastasis: a viable strategy for treatment of unresectable chemotherapy refractory colorectal cancer liver metastases. | American journal of clinical oncology 20061201 |
Chemoprevention of colorectal cancer: two steps forward, one step back? | Future oncology (London, England) 20061201 |
Clinical activity of celecoxib in metastatic malignant melanoma. | Cancer investigation 20061201 |
Assessment of celecoxib pharmacodynamics in pancreatic cancer. | Molecular cancer therapeutics 20061201 |
Do selective COX-2 inhibitors increase the risk of cerebrovascular events? A meta-analysis of randomized controlled trials. | Journal of clinical pharmacy and therapeutics 20061201 |
The cyclooxygenase 2 genetic variant -765G>C does not modulate the effects of celecoxib on prostaglandin E2 production. | Clinical pharmacology and therapeutics 20061201 |
Is the demonstration of adenoma reduction with rofecoxib a pyrrhic victory? | Gastroenterology 20061201 |
The suspension of treatments in ADAPT: concerns beyond the cardiovascular safety of celecoxib or naproxen. | PLoS clinical trials 20061201 |
Pro- and anti-inflammatory activities of the latex from Calotropis procera (Ait.) R.Br. are triggered by compounds fractionated by dialysis. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20061201 |
Dissolution of celecoxib from mucoadhesive disks based on polyaspartamide derivatives. | Acta pharmaceutica (Zagreb, Croatia) 20061201 |
Risks and benefits of celecoxib to prevent colorectal adenomas. | The New England journal of medicine 20061130 |
9-cis-Retinoic acid inhibition of lung carcinogenesis in the A/J mouse model is accompanied by increased expression of RAR-beta but no change in cyclooxygenase-2. | Cancer letters 20061128 |
Acute pulmonary inflammation induced by exposure of the airways to staphylococcal enterotoxin type B in rats. | Toxicology and applied pharmacology 20061115 |
Gene expression profiling in R-flurbiprofen-treated prostate cancer: R-Flurbiprofen regulates prostate stem cell antigen through activation of AKT kinase. | Biochemical pharmacology 20061115 |
Outcome of peptic ulcer bleeding among users of traditional non-steroidal anti-inflammatory drugs and selective cyclo-oxygenase-2 inhibitors. | Alimentary pharmacology & therapeutics 20061115 |
Efficacy of celecoxib in the treatment of CNS lymphomas: an in vivo model. | Neurosurgical focus 20061115 |
Nonsteroidal anti-inflammatory drug use in ankylosing spondylitis--a population-based survey. | Clinical rheumatology 20061101 |
A randomized double-blind placebo-controlled phase II trial of the cyclooxygenase-2 inhibitor Celecoxib in the treatment of cervical dysplasia. | Gynecologic oncology 20061101 |
Simultaneous quantitation of rosuvastatin and gemfibrozil in human plasma by high-performance liquid chromatography and its application to a pharmacokinetic study. | Biomedical chromatography : BMC 20061101 |
Overcoming trastuzumab resistance in HER2-overexpressing breast cancer cells by using a novel celecoxib-derived phosphoinositide-dependent kinase-1 inhibitor. | Molecular pharmacology 20061101 |
Urine PGE-M: A metabolite of prostaglandin E2 as a potential biomarker of advanced colorectal neoplasia. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20061101 |
Association of selective and conventional nonsteroidal antiinflammatory drugs with acute renal failure: A population-based, nested case-control analysis. | American journal of epidemiology 20061101 |
Celecoxib reduces microvessel density in patients treated with nasopharyngeal carcinoma and induces changes in gene expression. | Annals of oncology : official journal of the European Society for Medical Oncology 20061101 |
Does celecoxib have an adverse effect on bone remodeling and ingrowth in humans? | Clinical orthopaedics and related research 20061101 |
A feasibility study of the efficacy and tolerability of the combination of Exemestane with the COX-2 inhibitor Celecoxib in post-menopausal patients with advanced breast cancer. | European journal of cancer (Oxford, England : 1990) 20061101 |
Celecoxib allergies and cross-reactivity. | Internal medicine journal 20061101 |
The analgesic efficacy of celecoxib, pregabalin, and their combination for spinal fusion surgery. | Anesthesia and analgesia 20061101 |
Transcriptional profiling of tumor biopsies in oncology trials--a 'window' of opportunity for evaluating new drugs in nasopharyngeal cancer? | Annals of oncology : official journal of the European Society for Medical Oncology 20061101 |
Is ranitidine therapy sufficient for healing peptic ulcers associated with non-steroidal anti-inflammatory drug use? | International journal of clinical practice 20061101 |
Case of acrodermatitis continua accompanied by psoriatic arthritis. | The Journal of dermatology 20061101 |
Simultaneous assessment of short-term gastrointestinal benefits and cardiovascular risks of selective cyclooxygenase 2 inhibitors and nonselective nonsteroidal antiinflammatory drugs: an instrumental variable analysis. | Arthritis and rheumatism 20061101 |
The use of celecoxib and dexamethasone for the prevention and control of postoperative pain after periodontal surgery. | Journal of periodontology 20061101 |
[Chemopreventive effect of tamoxifen combined with celecoxib on DMBA-induced breast cancer in rats]. | Ai zheng = Aizheng = Chinese journal of cancer 20061101 |
Cardiovascular and cerebrovascular events in the randomized, controlled Alzheimer's Disease Anti-Inflammatory Prevention Trial (ADAPT). | PLoS clinical trials 20061101 |
ADAPT: the wrong way to stop a clinical trial. | PLoS clinical trials 20061101 |
A pilot pharmacokinetic and antiangiogenic biomarker study of celecoxib and low-dose metronomic vinblastine or cyclophosphamide in pediatric recurrent solid tumors. | Journal of pediatric hematology/oncology 20061101 |
[Chemopreventive effect of celecoxib against DMBA-induced breast cancer and its mechanism]. | Nan fang yi ke da xue xue bao = Journal of Southern Medical University 20061101 |
Inhibition of 5-lipoxygenase by MK886 augments the antitumor activity of celecoxib in human colon cancer cells. | Molecular cancer therapeutics 20061101 |
Nonsteroidal anti-inflammatory drugs: cyclooxygenase 2 inhibitors. | Jornal de pediatria 20061101 |
Cardiovascular events associated with the use of four nonselective NSAIDs (etodolac, nabumetone, ibuprofen, or naproxen) versus a cyclooxygenase-2 inhibitor (celecoxib): a population-based analysis in Taiwanese adults. | Clinical therapeutics 20061101 |
Inhibitors of cyclooxygenases: mechanisms, selectivity and uses. | Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20061101 |
[Inhibited proliferation and expression of human nasopharyngeal carcinoma line induced by celecoxib in vitro]. | Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery 20061101 |
[Non-steroidal anti-inflammatory drug induced gastropathy and preventive effects of teprenone on the gastropathy in rats]. | Zhonghua yi xue za zhi 20061031 |
Tolerance to celecoxib in patients with a history of adverse reactions to nonsteroidal anti-inflammatory drugs. | Swiss medical weekly 20061028 |
Differential effect of celecoxib on tissue factor expression in human endothelial and vascular smooth muscle cells. | Biochemical and biophysical research communications 20061020 |
Did targeted therapy fail cyclooxygenase too? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061020 |
Randomized phase II trial of docetaxel/irinotecan and gemcitabine/irinotecan with or without celecoxib in the second-line treatment of non-small-cell lung cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20061020 |
Effect of simultaneous inhibition of epidermal growth factor receptor and cyclooxygenase-2 in HER-2/neu-positive breast cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20061015 |
Celecoxib could reverse the hypoxia-induced Angiopoietin-2 upregulation in gastric cancer. | Cancer letters 20061008 |
Cardiovascular risk and inhibition of cyclooxygenase: a systematic review of the observational studies of selective and nonselective inhibitors of cyclooxygenase 2. | JAMA 20061004 |
Adverse effects of cyclooxygenase 2 inhibitors on renal and arrhythmia events: meta-analysis of randomized trials. | JAMA 20061004 |
Simultaneous estimation of six anti-diabetic drugs--glibenclamide, gliclazide, glipizide, pioglitazone, repaglinide and rosiglitazone: development of a novel HPLC method for use in the analysis of pharmaceutical formulations and its application to human plasma assay. | Biomedical chromatography : BMC 20061001 |
GADD153 mediates celecoxib-induced apoptosis in cervical cancer cells. | Carcinogenesis 20061001 |
Roles of COX-2 and iNOS in the bony repair of the injured growth plate cartilage. | Journal of cellular biochemistry 20061001 |
Docosahexaenoic acid in combination with celecoxib modulates HSP70 and p53 proteins in prostate cancer cells. | International journal of cancer 20061001 |
Inhibition profiling of human carbonic anhydrase II by high-throughput screening of structurally diverse, biologically active compounds. | Journal of biomolecular screening 20061001 |
Neutrophil migration in mice induced by a mannose-binding lectin isolated from Annona coriacea seeds. | Toxicon : official journal of the International Society on Toxinology 20061001 |
Risk of hospitalization for angio-oedema among users of newer COX-2 selective inhibitors and other nonsteroidal anti-inflammatory drugs. | British journal of clinical pharmacology 20061001 |
Cardiorenal effects of celecoxib as compared with the nonsteroidal anti-inflammatory drugs diclofenac and ibuprofen. | Kidney international 20061001 |
Can the blood pressure effects of COX-2 selective inhibitors be explained by changes in plasma aldosterone levels? | Journal of hypertension 20061001 |
Cyclooxygenase-2 directly regulates gene expression of P450 Cyp19 aromatase promoter regions pII, pI.3 and pI.7 and estradiol production in human breast tumor cells. | Prostaglandins & other lipid mediators 20061001 |
Nonsteroidal antiinflammatory drugs and acute myocardial infarction in patients with no major risk factors. | Pharmacotherapy 20061001 |
The associations between severity of early postoperative pain, chronic postsurgical pain and plasma concentration of stable nitric oxide products after breast surgery. | Anesthesia and analgesia 20061001 |
Extent of renal effect of cyclo-oxygenase-2-selective inhibitors is pharmacokinetic dependent. | Clinical and experimental pharmacology & physiology 20061001 |
Bovine and porcine transscleral solute transport: influence of lipophilicity and the Choroid-Bruch's layer. | Investigative ophthalmology & visual science 20061001 |
Chemopreventive effect of celecoxib in oral precancers and cancers. | The Laryngoscope 20061001 |
COX-2 inhibitors and cardiovascular risk. Inferences based on biology and clinical studies. | Thrombosis and haemostasis 20061001 |
Does a coxib-associated thrombotic risk limit the clinical use of the compounds as analgesic anti-inflammatory drugs? Arguments in favor. | Thrombosis and haemostasis 20061001 |
Selective COX-2 inhibitors and risk of thromboembolic events - regulatory aspects. | Thrombosis and haemostasis 20061001 |
Therapeutic levels of aspirin and salicylate directly inhibit a model of angiogenesis through a Cox-independent mechanism. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20061001 |
Cyclooxygenase-2 inhibition and regression of metastatic melanoma. | Melanoma research 20061001 |
Involvement of mitochondrial and Akt signaling pathways in augmented apoptosis induced by a combination of low doses of celecoxib and N-(4-hydroxyphenyl) retinamide in premalignant human bronchial epithelial cells. | Cancer research 20061001 |
Different eicosanoid profile of the hypersensitivity reactions triggered by aspirin and celecoxib in a patient with sinusitis, asthma, and urticaria. | The Journal of allergy and clinical immunology 20061001 |
Inhibition of the cyclooxygenase pathway attenuates morphine-induced conditioned place preference in mice. | Pharmacology, biochemistry, and behavior 20061001 |
[Prophylactic effect of a selective COX-2 inhibitor celecoxib on carcinogen-induced gastric premalignant lesions in rats]. | Ai zheng = Aizheng = Chinese journal of cancer 20061001 |
Trying times for painkiller choices. Vioxx, Bextra, and Celebrex can increase the risk for heart attack and other cardiovascular problems. So can the old standbys, like ibuprofen and acetaminophen. | Harvard heart letter : from Harvard Medical School 20061001 |
Increased Leishmania replication in HIV-1-infected macrophages is mediated by tat protein through cyclooxygenase-2 expression and prostaglandin E2 synthesis. | The Journal of infectious diseases 20060915 |
CCL3/macrophage inflammatory protein-1alpha induces fever and increases prostaglandin E2 in cerebrospinal fluid of rats: effect of antipyretic drugs. | Brain research 20060913 |
Inhibition of cyclooxygenase (COX)-2 affects endothelial progenitor cell proliferation. | Experimental cell research 20060910 |
Effect of celecoxib on cardiovascular events and blood pressure in two trials for the prevention of colorectal adenomas. | Circulation 20060905 |
Cardiovascular risk of selective cyclooxygenase-2 inhibitors and other non-aspirin non-steroidal anti-inflammatory medications. | Pharmacoepidemiology and drug safety 20060901 |
Celecoxib inhibits nitric oxide production in chondrocytes of ligament-damaged osteoarthritic rat joints. | Rheumatology international 20060901 |
Effect of COX-2 inhibitors and non-steroidal anti-inflammatory drugs on a mouse fracture model. | Injury 20060901 |
Involvement of the 5-lipoxygenase/leukotriene A4 hydrolase pathway in 7,12-dimethylbenz[a]anthracene (DMBA)-induced oral carcinogenesis in hamster cheek pouch, and inhibition of carcinogenesis by its inhibitors. | Carcinogenesis 20060901 |
Role of the cyclooxygenase pathway in the protection against postischemic stunning in conscious sheep. | Molecular and cellular biochemistry 20060901 |
Cycloxygenase-2 activity promotes cognitive deficits but not increased amyloid burden in a model of Alzheimer's disease in a sex-dimorphic pattern. | Neuroscience 20060901 |
Tumour necrosis factor-alpha blockers: potential limitations in the management of advanced endometriosis? A case report. | Human reproduction (Oxford, England) 20060901 |
Design and synthesis of new water-soluble tetrazolide derivatives of celecoxib and rofecoxib as selective cyclooxygenase-2 (COX-2) inhibitors. | Bioorganic & medicinal chemistry letters 20060901 |
Selective COX-2 inhibitors. Part 1: synthesis and biological evaluation of phenylazobenzenesulfonamides. | Bioorganic & medicinal chemistry letters 20060901 |
Inhalation delivery and anti-tumor activity of celecoxib in human orthotopic non-small cell lung cancer xenograft model. | Pharmaceutical research 20060901 |
Celecoxib in the treatment of haemophilic synovitis, target joints, and pain in adults and children with haemophilia. | Haemophilia : the official journal of the World Federation of Hemophilia 20060901 |
Cyclooxygenase-2 inhibitors and coronary occlusion--exploring dose-response relationships. | British journal of clinical pharmacology 20060901 |
The effect of the withdrawal of rofecoxib on prescribing patterns of COX-2 inhibitors in Scotland. | British journal of clinical pharmacology 20060901 |
High-Dose celecoxib and metronomic 'low-dose' cyclophosphamide is an effective and safe therapy in patients with relapsed and refractory aggressive histology non-Hodgkin's lymphoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060901 |
Celecoxib, ibuprofen, and the antiplatelet effect of aspirin in patients with osteoarthritis and ischemic heart disease. | Clinical pharmacology and therapeutics 20060901 |
Is celecoxib an inducer of cytochrome P450 3A4 in subjects carrying the CYP2C9*3 allele? | Clinical pharmacology and therapeutics 20060901 |
Cyclooxygenase-2 plays an essential part in cardioprotection of delayed phase of recombinant human erythropoietin preconditioning in rats. | Postgraduate medical journal 20060901 |
Are COX-2 inhibitors safe for anyone. | Inflammatory bowel diseases 20060901 |
Celecoxib is efficacious and well tolerated in treating signs and symptoms of ankylosing spondylitis. | The Journal of rheumatology 20060901 |
Liquid-chromatographic separation and determination of process-related impurities, including a regio-specific isomer of celecoxib on reversed-phase C18 column dynamically coated with hexamethyldisilazane. | Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20060901 |
Proteomic profiling identifies cyclooxygenase-2-independent global proteomic changes by celecoxib in colorectal cancer cells. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20060901 |
Valdecoxib does not interfere with the CYP2D6 substrate metoprolol. | International journal of clinical pharmacology and therapeutics 20060901 |
[A case of complete regression of hepatocellular carcinoma during administration of COX-2 inhibitor]. | The Korean journal of hepatology 20060901 |
Impact of cyclooxygenase inhibitors in the Women's Health Initiative hormone trials: secondary analysis of a randomized trial. | PLoS clinical trials 20060901 |
Influence of hydrophilic polymers on celecoxib complexation with hydroxypropyl beta-cyclodextrin. | AAPS PharmSciTech 20060901 |
[Effects of nonsteroidal anti-inflammatory drug celecoxib on expression of cyclooxygenase-2 (COX-2) in ovarian carcinoma cell]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20060901 |
Predictors of the selection of coxibs over nonselective NSAIDs in an older Medicaid cohort. | The American journal of geriatric pharmacotherapy 20060901 |
[What do we know about the cardiovascular toxicity of the NSAIDs?]. | Presse medicale (Paris, France : 1983) 20060901 |
[Are there any differences in the cardiovascular tolerance between classical NSAIDs and coxibs?]. | Presse medicale (Paris, France : 1983) 20060901 |
Paired drugs give advanced lung cancer a double punch. | Health news (Waltham, Mass.) 20060901 |
Critical appraisal of C-reactive protein throughout the spectrum of cardiovascular disease. | Vascular health and risk management 20060901 |
[What do we know about the cardiovascular toxicity of the NSAIDs?]. | Presse medicale (Paris, France : 1983) 20060901 |
[Are there any differences in the cardiovascular tolerance between classical NSAIDs and coxibs?]. | Presse medicale (Paris, France : 1983) 20060901 |
Prophylaxis of migraine. | Neuropsychiatric disease and treatment 20060901 |
Celecoxib for the prevention of sporadic colorectal adenomas. | The New England journal of medicine 20060831 |
Celecoxib for the prevention of colorectal adenomatous polyps. | The New England journal of medicine 20060831 |
Risks and benefits of celecoxib to prevent recurrent adenomas. | The New England journal of medicine 20060831 |
Cyclooxygenase-2 inhibitor enhances the efficacy of a breast cancer vaccine: role of IDO. | Journal of immunology (Baltimore, Md. : 1950) 20060815 |
Radiosensitivity enhancement by combined treatment of celecoxib and gefitinib on human lung cancer cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060815 |
Ariad Pharmaceuticals wins first round over Eli Lilly, patents on methods can be far-reaching. | Journal of the National Cancer Institute 20060802 |
Long term NSAID treatment inhibits COX-2 synthesis in the knee synovial membrane of patients with osteoarthritis: differential proinflammatory cytokine profile between celecoxib and aceclofenac. | Annals of the rheumatic diseases 20060801 |
Reversible binding of celecoxib and valdecoxib with human serum albumin using fluorescence spectroscopic technique. | Pharmacological research 20060801 |
Prevention of nephrolithiasis by Lactobacillus in stone-forming rats: a preliminary study. | Urological research 20060801 |
Covalent binding of radioactivity from [14C]rofecoxib, but not [14C]celecoxib or [14C]CS-706, to the arterial elastin of rats. | Drug metabolism and disposition: the biological fate of chemicals 20060801 |
N-acylated sulfonamide sodium salt: a prodrug of choice for the bifunctional 2-hydroxymethyl-4-(5-phenyl-3-trifluoromethyl-pyrazol-1-yl) benzenesulfonamide class of COX-2 inhibitors. | Bioorganic & medicinal chemistry letters 20060801 |
Cyclooxygenase-2 inhibitor, celecoxib, inhibits the altered hippocampal neurogenesis with attenuation of spontaneous recurrent seizures following pilocarpine-induced status epilepticus. | Neurobiology of disease 20060801 |
Celecoxib inhibits cellular growth, decreases Ki-67 expression and modifies apoptosis in ovarian cancer cell lines. | Archives of medical research 20060801 |
Selective COX-2 inhibitor celecoxib prevents experimental autoimmune encephalomyelitis through COX-2-independent pathway. | Brain : a journal of neurology 20060801 |
Prevention of intra-abdominal adhesions using the antiangiogenic COX-2 inhibitor celecoxib. | Annals of surgery 20060801 |
Perioperative cyclooxygenase 2 inhibition to reduce tumor cell adhesion and metastatic potential of circulating tumor cells in non-small cell lung cancer. | The Journal of thoracic and cardiovascular surgery 20060801 |
The COX-2 inhibitors--an update. | American heart journal 20060801 |
CD24 is a new oncogene, early at the multistep process of colorectal cancer carcinogenesis. | Gastroenterology 20060801 |
Molecular responses of rectal cancer to preoperative chemoradiation. | Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20060801 |
Interaction of macrophages with apoptotic cells enhances HIV Type 1 replication through PGE2, PAF, and vitronectin receptor. | AIDS research and human retroviruses 20060801 |
Fracture risk associated with use of nonsteroidal anti-inflammatory drugs, acetylsalicylic acid, and acetaminophen and the effects of rheumatoid arthritis and osteoarthritis. | Calcified tissue international 20060801 |
How specific are 'target-specific' drugs? Celecoxib as a case in point. | Molecular interventions 20060801 |
Celecoxib-loaded poly(D,L-lactide-co-glycolide) nanoparticles prepared using a novel and controllable combination of diffusion and emulsification steps as part of the salting-out procedure. | Journal of microencapsulation 20060801 |
Hepatic disorders in patients treated with COX-2 selective inhibitors or nonselective NSAIDs: a case/noncase analysis of spontaneous reports. | Clinical therapeutics 20060801 |
Interleukin-13 enhances cyclooxygenase-2 expression in activated rat brain microglia: implications for death of activated microglia. | Journal of immunology (Baltimore, Md. : 1950) 20060715 |
Cyclooxygenase-2 inhibition induces apoptosis signaling via death receptors and mitochondria in hepatocellular carcinoma. | Cancer research 20060715 |
Chemoprevention of familial adenomatous polyposis by low doses of atorvastatin and celecoxib given individually and in combination to APCMin mice. | Cancer research 20060715 |
Therapy switching and associated costs in elderly patients receiving COX-2 selective inhibitors or non-selective non-steroidal anti-inflammatory drugs in Quebec, Canada. | Rheumatology (Oxford, England) 20060701 |
Green tea polyphenol stimulates cancer preventive effects of celecoxib in human lung cancer cells by upregulation of GADD153 gene. | International journal of cancer 20060701 |
Low-intensity pulsed ultrasound accelerates and a nonsteroidal anti-inflammatory drug delays knee ligament healing. | The American journal of sports medicine 20060701 |
Cyclooxygenase-2 selective inhibition suppresses restoration of tibial trabecular bone formation in association with restriction of osteoblast maturation in skeletal reloading after hindlimb elevation of mice. | Bone 20060701 |
The cyclooxygenase-2 inhibitor celecoxib has therapeutic effects in major depression: results of a double-blind, randomized, placebo controlled, add-on pilot study to reboxetine. | Molecular psychiatry 20060701 |
Improved solubilization of Celecoxib in U-type nonionic microemulsions and their structural transitions with progressive aqueous dilution. | Journal of colloid and interface science 20060701 |
Orofacial cold hyperalgesia due to infraorbital nerve constriction injury in rats: reversal by endothelin receptor antagonists but not non-steroidal anti-inflammatory drugs. | Pain 20060701 |
Endogenous opioids mediate the hypoalgesia induced by selective inhibitors of cyclo-oxygenase 2 in rat paws treated with carrageenan. | Neuropharmacology 20060701 |
Cyclooxygenase-2 selective nonsteroidal anti-inflammatory drugs and the risk of ischemic stroke: a nested case-control study. | Stroke 20060701 |
NSAID use and the risk of hospitalization for first myocardial infarction in the general population: a nationwide case-control study from Finland. | European heart journal 20060701 |
Trial of celecoxib in amyotrophic lateral sclerosis. | Annals of neurology 20060701 |
Newer cyclo-oxygenase-2 selective inhibitors, other non-steroidal anti-inflammatory drugs and the risk of acute pancreatitis. | Alimentary pharmacology & therapeutics 20060701 |
Increases in circulating VEGF levels during COX-2 inhibitor treatment in breast cancer patients. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20060701 |
Gastric mucosal cell model for estimating relative gastrointestinal toxicity of non-steroidal anti-inflammatory drugs. | Prostaglandins, leukotrienes, and essential fatty acids 20060701 |
Celecoxib. | Journal of the Royal Society of Medicine 20060701 |
The crucial role of cyclooxygenase-2 in osteopontin-induced protein kinase C alpha/c-Src/IkappaB kinase alpha/beta-dependent prostate tumor progression and angiogenesis. | Cancer research 20060701 |
Gene expression differences in normal esophageal mucosa associated with regression and progression of mild and moderate squamous dysplasia in a high-risk Chinese population. | Cancer research 20060701 |
Development and in vitro evaluation of oral controlled release formulations of celecoxib using optimization techniques. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20060701 |
Rofecoxib 12.5 mg, rofecoxib 25 mg, and celecoxib 200 mg in the treatment of symptomatic osteoarthritis: results of two similarly designed studies. | Current medical research and opinion 20060701 |
Celecoxib treatment alters the gene expression profile of normal colonic mucosa. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20060701 |
Determine whether perioperative celecoxib administration would reduce opioid consumption and provide effective pain relief in patients undergoing arthroscopic knee surgery. | Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association 20060701 |
Combined biodifferentiating and antiangiogenic oral metronomic therapy is feasible and effective in relapsed solid tumors in children: single-center pilot study. | Onkologie 20060701 |
[Effects of selective and non-selective cyclooxygenase-2 inhibitor on the growth of colon cancer cells]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20060701 |
Celecoxib can induce cell death independently of cyclooxygenase-2, p53, Mdm2, c-Abl and reactive oxygen species. | Anti-cancer drugs 20060701 |
[Cyclooxygenase inhibitors: a never ending story?]. | Giornale italiano di cardiologia (2006) 20060701 |
Subacute toxicity of celecoxib on thyroid and testis of rats: Hormonal and histopathological changes. | Environmental toxicology and pharmacology 20060701 |
Heterogeneous nuclear ribonuclear protein C is increased in the celecoxib-induced growth inhibition of human oral squamous cell carcinoma. | Experimental & molecular medicine 20060630 |
Role of p21CIP1 as a determinant of SC-560 response in human HCT116 colon carcinoma cells. | Experimental & molecular medicine 20060630 |
Risk of death or reinfarction associated with the use of selective cyclooxygenase-2 inhibitors and nonselective nonsteroidal antiinflammatory drugs after acute myocardial infarction. | Circulation 20060627 |
Cyclooxygenase-2 selective inhibitors and prostate cancer: what is the clinical benefit? | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060620 |
Celecoxib versus placebo for men with prostate cancer and a rising serum prostate-specific antigen after radical prostatectomy and/or radiation therapy. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20060620 |
Changes in antitumor response in C57BL/6J-Min/+ mice during long-term administration of a selective cyclooxygenase-2 inhibitor. | Cancer research 20060615 |
Increased expression of cyclooxygenase-2 mediates enhanced contraction to endothelin ETA receptor stimulation in endothelial nitric oxide synthase knockout mice. | Circulation research 20060609 |
Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors. | Journal of the National Cancer Institute 20060607 |
Pharmacological separation between peripheral and central functions of cyclooxygenase-2 with CIAA, a novel cyclooxygenase-2 inhibitor. | European journal of pharmacology 20060606 |
The effects of celecoxib augmentation on cytokine levels in schizophrenia. | The international journal of neuropsychopharmacology 20060601 |
Heregulin-alpha and heregulin-beta expression is linked to a COX-2-PGE2 pathway in human gastric fibroblasts. | American journal of physiology. Gastrointestinal and liver physiology 20060601 |
Oncogenic RAS mutations in myeloma cells selectively induce cox-2 expression, which participates in enhanced adhesion to fibronectin and chemoresistance. | Blood 20060601 |
Phase II study of celecoxib in metastatic differentiated thyroid carcinoma. | The Journal of clinical endocrinology and metabolism 20060601 |
Luminal delivery and dosing considerations of local celecoxib administration to colorectal cancer. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20060601 |
Getting it right: being smarter about clinical trials. | PLoS medicine 20060601 |
Interferon-alpha resistance can be reversed by inhibition of IFN-alpha-induced COX-2 expression potentially via STAT1 activation in A549 cells. | Oncology reports 20060601 |
A phase I trial to determine the optimal biological dose of celecoxib when combined with erlotinib in advanced non-small cell lung cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060601 |
Design and evaluation of celecoxib porous particles using melt sonocrystallization. | Pharmaceutical research 20060601 |
Efficacy and tolerability of celecoxib compared with diclofenac slow release in the treatment of acute ankle sprain in an Asian population. | Singapore medical journal 20060601 |
Retrospective study of capecitabine and celecoxib in metastatic colorectal cancer: potential benefits and COX-2 as the common mediator in pain, toxicities and survival? | American journal of clinical oncology 20060601 |
Effect of indomethacin and selective cyclooxygenase-2 inhibitors on proteinuria and renal function in patients with AA type renal amyloidosis. | Nephrology (Carlton, Vic.) 20060601 |
FOLFIRI with or without celecoxib in advanced colorectal cancer: a randomized phase II study of the Gruppo Oncologico dell'Italia Meridionale (GOIM). | Annals of oncology : official journal of the European Society for Medical Oncology 20060601 |
Analgesic efficacy of perioperative celecoxib in ambulatory arthroscopic knee surgery: a double-blind, placebo-controlled study. | Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association 20060601 |
Ankylosing spondylitis and symptom-modifying vs disease-modifying therapy. | Best practice & research. Clinical rheumatology 20060601 |
Low-intensity electromagnetic millimeter waves for pain therapy. | Evidence-based complementary and alternative medicine : eCAM 20060601 |
Cyclooxygenase-2 inhibitors: a painful lesson. | Cardiovascular & hematological disorders drug targets 20060601 |
Use of accelerating solvent extraction for detecting non-steroidal anti-inflammatory drugs in horse feces. | Journal of analytical toxicology 20060601 |
[Molecular-targeted therapy for hormone-refractory prostate cancer]. | Hinyokika kiyo. Acta urologica Japonica 20060601 |
Changes in the immune system in depression and dementia: causal or coincidental effects? | Dialogues in clinical neuroscience 20060601 |
Detection of overexpressed COX-2 in precancerous lesions of hamster pancreas and lungs by molecular imaging: implications for early diagnosis and prevention. | ChemMedChem 20060601 |
Risk of cardiovascular events and cyclooxygenase-2 inhibitors. | Vascular health and risk management 20060601 |
Clinical implications of angiogenesis in cancers. | Vascular health and risk management 20060601 |
Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer-Part 2. | Current oncology (Toronto, Ont.) 20060601 |
Inhibition of phorbol ester-induced mouse skin tumor promotion and COX-2 expression by celecoxib: C/EBP as a potential molecular target. | Cancer research and treatment : official journal of Korean Cancer Association 20060601 |
[Cytotoxic activities of Celecoxib on leukemic cells and the synergistic effects of Celecoxib with Imatinib thereupon]. | Zhonghua yi xue za zhi 20060530 |
Time variations in the risk of myocardial infarction among elderly users of COX-2 inhibitors. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20060523 |
Celecoxib shown effective in preventing colon polyps. | Journal of the National Cancer Institute 20060517 |
Celecoxib induces anoikis in human colon carcinoma cells associated with the deregulation of focal adhesions and nuclear translocation of p130Cas. | International journal of cancer 20060515 |
The impact of low-dose aspirin on endoscopic gastric and duodenal ulcer rates in users of a non-selective non-steroidal anti-inflammatory drug or a cyclo-oxygenase-2-selective inhibitor. | Alimentary pharmacology & therapeutics 20060515 |
Cyclooxygenase-2-dependent regulation of E-cadherin: prostaglandin E(2) induces transcriptional repressors ZEB1 and snail in non-small cell lung cancer. | Cancer research 20060515 |
HER-2/neu status is a determinant of mammary aromatase activity in vivo: evidence for a cyclooxygenase-2-dependent mechanism. | Cancer research 20060515 |
Influence of modified cyclodextrins on solubility and percutaneous absorption of celecoxib through human skin. | International journal of pharmaceutics 20060511 |
RNA interference as a key to knockdown overexpressed cyclooxygenase-2 gene in tumour cells. | British journal of cancer 20060508 |
Phase I and pharmacokinetic study of docetaxel, irinotecan, and celecoxib in patients with advanced non-small cell lung cancer. | Investigational new drugs 20060501 |
Short-term dietary administration of celecoxib enhances the efficacy of tumor lysate-pulsed dendritic cell vaccines in treating murine breast cancer. | International journal of cancer 20060501 |
Combination chemotherapy with 13-cis-retinoic acid and celecoxib in the treatment of glioblastoma multiforme. | Journal of neuro-oncology 20060501 |
Celecoxib inhibits interleukin-12 alphabeta and beta2 folding and secretion by a novel COX2-independent mechanism involving chaperones of the endoplasmic reticulum. | Molecular pharmacology 20060501 |
Selective cyclooxygenase-2 inhibition with celecoxib decreases angiotensin II-induced abdominal aortic aneurysm formation in mice. | Arteriosclerosis, thrombosis, and vascular biology 20060501 |
Simple and rapid high-performance liquid chromatographic method for determination of celecoxib in plasma using UV detection: application in pharmacokinetic studies. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060501 |
Update on nonsteriodal anti-inflammatory drugs. | Current opinion in rheumatology 20060501 |
Microsphere-based protease assays and screening application for lethal factor and factor Xa. | Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501 |
COX-2 in cardiovascular disease. | Arteriosclerosis, thrombosis, and vascular biology 20060501 |
A randomized database study in general practice yielded quality data but patient recruitment in routine consultation was not practical. | Journal of clinical epidemiology 20060501 |
Neuroprotective agents in schizophrenia and affective disorders. | Expert opinion on pharmacotherapy 20060501 |
Cardiovascular outcomes in new users of coxibs and nonsteroidal antiinflammatory drugs: high-risk subgroups and time course of risk. | Arthritis and rheumatism 20060501 |
A phase II study with antioxidants, both in the diet and supplemented, pharmaconutritional support, progestagen, and anti-cyclooxygenase-2 showing efficacy and safety in patients with cancer-related anorexia/cachexia and oxidative stress. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20060501 |
Motexafin gadolinium modulates levels of phosphorylated Akt and synergizes with inhibitors of Akt phosphorylation. | Molecular cancer therapeutics 20060501 |
Celecoxib exposures reported to Texas poison control centers from 1999 to 2004. | Human & experimental toxicology 20060501 |
Simultaneous determination of celecoxib, meloxicam, and rofecoxib using capillary electrophoresis with surfactant and application in drug formulations. | Journal of separation science 20060501 |
The role of the New Zealand Intensive Medicines Monitoring Programme in identification of previously unrecognised signals of adverse drug reactions. | Current drug safety 20060501 |
Use of first- and second-generation cyclooxygenase-2-selective nonsteroidal antiinflammatory drugs and risk of acute myocardial infarction. | Circulation 20060425 |
COX-2-mediated stimulation of the lymphangiogenic factor VEGF-C in human breast cancer. | British journal of cancer 20060424 |
Bile acid-mediated induction of cyclooxygenase-2 and Mcl-1 in hepatic stellate cells. | Biochemical and biophysical research communications 20060421 |
Design, synthesis, and biological evaluation of substituted 3-alkylthio-4,5-diaryl-4H-1,2,4-triazoles as selective COX-2 inhibitors. | Bioorganic & medicinal chemistry 20060415 |
Prevention of azoxymethane-induced colon cancer by combination of low doses of atorvastatin, aspirin, and celecoxib in F 344 rats. | Cancer research 20060415 |
Antitumor properties of dimethyl-celecoxib, a derivative of celecoxib that does not inhibit cyclooxygenase-2: implications for glioma therapy. | Neurosurgical focus 20060415 |
Differential regulation of anti-inflammatory proteins in human rheumatoid synoviocyte MH7A cell by celecoxib and ibuprofen. | Life sciences 20060404 |
Immune modulatory effects of cyclooxygenase type 2 inhibitors in HIV patients on combination antiretroviral treatment. | AIDS (London, England) 20060404 |
COX-2 inhibitors and pain after oral surgery - pertinent papers 2002-2003. | The British journal of oral & maxillofacial surgery 20060401 |
Roles of cyclooxygenase 2 and microsomal prostaglandin E synthase 1 in rat acid reflux oesophagitis. | Gut 20060401 |
Inhibition of COX-2 by celecoxib in the canine groove model of osteoarthritis. | Rheumatology (Oxford, England) 20060401 |
5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-trifluoromethylpyrazole acts in a reactive oxygen species-dependent manner to suppress human lung cancer growth. | Journal of cancer research and clinical oncology 20060401 |
COX-2 induces IL-11 production in human breast cancer cells. | The Journal of surgical research 20060401 |
Cytotoxicity of a non-cyclooxygenase-2 inhibitory derivative of celecoxib in non-small-cell lung cancer A549 cells. | Lung cancer (Amsterdam, Netherlands) 20060401 |
Selective cyclo-oxygenase 2 inhibition affects ileal but not colonic anastomotic healing in the early postoperative period. | The British journal of surgery 20060401 |
Effect of cyclooxygenase inhibitors on the micturition reflex in rats: correlation with inhibition of cyclooxygenase isozymes. | BJU international 20060401 |
Tolerance of diclofenac after hypersensitivity to celecoxib and to nabumetone. | British journal of clinical pharmacology 20060401 |
Antitumor effects of celecoxib on K562 leukemia cells are mediated by cell-cycle arrest, caspase-3 activation, and downregulation of Cox-2 expression and are synergistic with hydroxyurea or imatinib. | American journal of hematology 20060401 |
Arthritis supplement combination falls short in study. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20060401 |
COX-2 induction in mice with experimental nutritional steatohepatitis: Role as pro-inflammatory mediator. | Hepatology (Baltimore, Md.) 20060401 |
Unconvincing Pfizer and uncertain crucifixions. | Journal of the Royal Society of Medicine 20060401 |
Effects of selective cyclooxygenase-2 inhibitor and omega-3 fatty acid on serum interleukin-1beta, osteocalcin, and C-reactive protein levels in rats. | Journal of periodontology 20060401 |
Cardiovascular risk with cyclooxygenase inhibitors: general problem with substance specific differences? | Naunyn-Schmiedeberg's archives of pharmacology 20060401 |
Discordance between availability of pharmacogenetics studies and pharmacogenetics-based prescribing information for the top 200 drugs. | The Annals of pharmacotherapy 20060401 |
Disease mongering in drug promotion: do governments have a regulatory role? | PLoS medicine 20060401 |
COX-2 inhibitors and the heart: are all coxibs the same? | Postgraduate medical journal 20060401 |
Celecoxib up-regulates the expression of the zeta chain of T cell receptor complex in tumor-infiltrating lymphocytes in human cervical cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060401 |
Phase II trial of celecoxib in prostate-specific antigen recurrent prostate cancer after definitive radiation therapy or radical prostatectomy. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060401 |
[Inhibitory effects of cyclooxygenase-2 inhibitor celecoxib on growth and angiogenesis of human liver cancer HepG2 cell xenografts in small nude mice]. | Ai zheng = Aizheng = Chinese journal of cancer 20060401 |
Effects of cyclooxygenase-2 inhibition on serum and tumor gastrins and expression of apoptosis-related proteins in colorectal cancer. | Digestive diseases and sciences 20060401 |
Side-locked headache as the chief complaint of inflammatory orbital pseudotumor (myositic form): a case report. | Headache 20060401 |
[Three-dimensional trabecular bone microarchitecture in inflammatory bone destruction]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20060401 |
COX-2 has a critical role during incorporation of structural bone allografts. | Annals of the New York Academy of Sciences 20060401 |
Are there differences in the renal effects of selective cyclo-oxygenase 2 inhibitors? | Nature clinical practice. Nephrology 20060401 |
Genetic tools to tailor cancer prevention by NSAIDs. | Discovery medicine 20060401 |
Raltitrexed-eloxatin salvage chemotherapy in gemcitabine-resistant metastatic pancreatic cancer. | British journal of cancer 20060327 |
Promotion of prostatic metastatic migration towards human bone marrow stoma by Omega 6 and its inhibition by Omega 3 PUFAs. | British journal of cancer 20060327 |
Effect of glutamate receptor antagonists and antirheumatic drugs on proliferation of synoviocytes in vitro. | European journal of pharmacology 20060327 |
[Intestinal side effects of COX-2 inhibitors]. | Ugeskrift for laeger 20060327 |
Glycine-extended gastrin stimulates proliferation and inhibits apoptosis in colon cancer cells via cyclo-oxygenase-independent pathways. | Regulatory peptides 20060315 |
Molecular dynamics simulations of arachidonic acid-derived pentadienyl radical intermediate complexes with COX-1 and COX-2: insights into oxygenation regio- and stereoselectivity. | Biochemistry 20060314 |
Glycine-extended gastrin inhibits apoptosis in colon cancer cells via separate activation of Akt and JNK pathways. | Molecular and cellular endocrinology 20060309 |
Synthesis and structure-activity relationship studies of 1,3-diarylprop-2-yn-1-ones: dual inhibitors of cyclooxygenases and lipoxygenases. | Journal of medicinal chemistry 20060309 |
Role of cyclooxygenase-2 in the carcinogenesis of gastrointestinal tract cancers: a review and report of personal experience. | World journal of gastroenterology 20060307 |
Indomethacin and celecoxib impair rotator cuff tendon-to-bone healing. | The American journal of sports medicine 20060301 |
Kynurenic acid, an endogenous constituent of rheumatoid arthritis synovial fluid, inhibits proliferation of synoviocytes in vitro. | Rheumatology international 20060301 |
Involvement of cyclooxygenase-2 in gastric mucosal hypertrophy in gastrin transgenic mice. | American journal of physiology. Gastrointestinal and liver physiology 20060301 |
A time course analysis of cyclooxygenase-2 suggests a role in spatial memory retrieval in rats. | Neuroscience research 20060301 |
Influence of plasma protein on the potencies of inhibitors of cyclooxygenase-1 and -2. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20060301 |
Utilization and cost comparison of current and optimal prescribing of nonsteroidal antiinflammatory drugs in Quebec, Canada. | The Journal of rheumatology 20060301 |
Cyclooxygenase-2 inhibitors: what went wrong? | Current opinion in clinical nutrition and metabolic care 20060301 |
Celecoxib versus naproxen and diclofenac in osteoarthritis patients: SUCCESS-I Study. | The American journal of medicine 20060301 |
Single periocular injection of celecoxib-PLGA microparticles inhibits diabetes-induced elevations in retinal PGE2, VEGF, and vascular leakage. | Investigative ophthalmology & visual science 20060301 |
Risk of cardiovascular events and celecoxib: a systematic review and meta-analysis. | Journal of the Royal Society of Medicine 20060301 |
Accumulation of celecoxib with a 7-fold higher drug exposure in individuals homozygous for CYP2C9*3. | Clinical pharmacology and therapeutics 20060301 |
Glucosamine & chondroitin use questioned in mild cases. Drug combo benefits moderate-to-severe knee osteoarthritis, but not so with lesser cases. | Health news (Waltham, Mass.) 20060301 |
Anti-cancer effect of celecoxib and aerosolized docetaxel against human non-small cell lung cancer cell line, A549. | The Journal of pharmacy and pharmacology 20060301 |
Cyclooxygenase-2 inhibitors in human skeletal fracture healing. | Orthopedics 20060301 |
Determination of valdecoxib in serum using a HPLC-diode array detector and its application in a pharmacokinetic study. | Die Pharmazie 20060301 |
[COX-2 mediates U50488H-induced delayed cardioprotection in isolated rat heart]. | Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences 20060301 |
Non-steroidal antiinflammatory drugs and the risk of acute myocardial infarction. | Basic & clinical pharmacology & toxicology 20060301 |
Chronic effects of celecoxib, a cyclooxygenase-2 inhibitor, cause enhanced alcohol-induced liver steatosis in rats. | Inflammopharmacology 20060301 |
Etoricoxib for arthritis and pain management. | Therapeutics and clinical risk management 20060301 |
[Clinical management of adenomatous polyposis in patients with hereditary non-polyposis colorectal cancer and familial adenomatous polyposis]. | Zhonghua yi xue za zhi 20060227 |
Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. | The New England journal of medicine 20060223 |
Celecoxib upregulates endoplasmic reticulum chaperones that inhibit celecoxib-induced apoptosis in human gastric cells. | Oncogene 20060216 |
Adenocarcina of the mouse prostate growth inhibition by celecoxib: downregulation of transcription factors involved in COX-2 inhibition. | The Prostate 20060215 |
Deficient E-cadherin adhesion in C57BL/6J-Min/+ mice is associated with increased tyrosine kinase activity and RhoA-dependent actomyosin contractility. | Experimental cell research 20060215 |
Retrospective analysis of utilization patterns and cost implications of coxibs among seniors in Quebec, Canada: what is the potential impact of the withdrawal of rofecoxib? | Arthritis and rheumatism 20060215 |
COX inhibitors and breast cancer. | British journal of cancer 20060213 |
Targeting prostaglandin E2 receptors as an alternative strategy to block cyclooxygenase-2-dependent extracellular matrix-induced matrix metalloproteinase-9 expression by macrophages. | The Journal of biological chemistry 20060210 |
Bcl-2 switches the type of demise from apoptosis to necrosis via cyclooxygenase-2 upregulation in HeLa cell induced by hydrogen peroxide. | Cancer letters 20060208 |
Lumiracoxib is effective in the treatment of osteoarthritis of the knee: a prospective randomized 13-week study versus placebo and celecoxib. | Clinical rheumatology 20060201 |
The renal effects of the addition of low-dose aspirin to COX-2 selective and nonselective antiinflammatory drugs. | Clinical rheumatology 20060201 |
Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARalpha and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways. | Journal of cellular biochemistry 20060201 |
Curcumin synergistically potentiates the growth-inhibitory and pro-apoptotic effects of celecoxib in osteoarthritis synovial adherent cells. | Rheumatology (Oxford, England) 20060201 |
Characterization of a novel polymorphic form of celecoxib. | Journal of pharmaceutical sciences 20060201 |
Maximal COX-2 immunostaining and clinical response to celecoxib and interferon alpha therapy in metastatic renal cell carcinoma. | Cancer 20060201 |
The effect of celecoxib, a selective COX-2 inhibitor, on liver ischemia/reperfusion-induced oxidative stress in rats. | Hepatology research : the official journal of the Japan Society of Hepatology 20060201 |
Selective cyclooxygenase-2 inhibitors inhibit growth and induce apoptosis of bladder cancer. | Oncology reports 20060201 |
Suppression of adjuvant-induced arthritic bone destruction by cyclooxygenase-2 selective agents with and without inhibitory potency against carbonic anhydrase II. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20060201 |
Effect of celecoxib on experimental liver fibrosis in rat. | Liver international : official journal of the International Association for the Study of the Liver 20060201 |
Celecoxib leads to G2/M arrest by induction of p21 and down-regulation of cyclin B1 expression in a p53-independent manner. | European journal of cancer (Oxford, England : 1990) 20060201 |
Analgesic effects of intrathecally administered celecoxib, a cyclooxygenase-2 inhibitor, in the tail flick test and the formalin test in rats. | Acta anaesthesiologica Scandinavica 20060201 |
Cyclooxygenase-2 expression and effect of celecoxib in flurothyl-induced neonatal seizure. | International journal of experimental pathology 20060201 |
tNOX, an alternative target to COX-2 to explain the anticancer activities of non-steroidal anti-inflammatory drugs (NSAIDS). | Molecular and cellular biochemistry 20060201 |
A structurally optimized celecoxib derivative inhibits human pancreatic cancer cell growth. | Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20060201 |
Selective use of selective nonsteroidal anti-inflammatory drugs in inflammatory bowel disease. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20060201 |
Safety of celecoxib in patients with ulcerative colitis in remission: a randomized, placebo-controlled, pilot study. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20060201 |
Ocular adverse effects associated with cyclooxygenase-2 inhibitors. | Archives of ophthalmology (Chicago, Ill. : 1960) 20060201 |
[A case report of unresectable gallbladder cancer that responded remarkably to the combination of thalidomide, celecoxib, and gemcitabine]. | Gan to kagaku ryoho. Cancer & chemotherapy 20060201 |
Cyclooxygenase inhibitors in urinary bladder cancer: in vitro and in vivo effects. | Molecular cancer therapeutics 20060201 |
[Pseudoporphyria and coxib]. | Annales de dermatologie et de venereologie 20060201 |
Selective inhibition of COX-2 by a standardized CO2 extract of Humulus lupulus in vitro and its activity in a mouse model of zymosan-induced arthritis. | Planta medica 20060201 |
Celecoxib: new indication. Colorectal cancer: no preventive benefit. | Prescrire international 20060201 |
Survivin expression in in situ and invasive breast cancer relates to COX-2 expression and DCIS recurrence. | British journal of cancer 20060130 |
Scientific misconduct. Fraud upends oral cancer field, casting doubt on prevention trial. | Science (New York, N.Y.) 20060127 |
Acetaminophen for osteoarthritis. | The Cochrane database of systematic reviews 20060125 |
[Non-steroidal anti-inflammatory agents and prevention of colorectal adenomas and carcinomas]. | Ugeskrift for laeger 20060123 |
[Nonspecific interstitial pneumonia: epidemiologic and clinical characteristics]. | Medicina clinica 20060121 |
Determination of celecoxib in human plasma and breast milk by high-performance liquid chromatographic assay. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060118 |
Years of research come to fruition with launch of oral cancer prevention trial. | Journal of the National Cancer Institute 20060118 |
Enhancement of antitumor activity of docetaxel by celecoxib in lung tumors. | International journal of cancer 20060115 |
Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II 'selective' inhibitor celecoxib. | Bioorganic & medicinal chemistry letters 20060115 |
Simultaneous quantitation of etoricoxib, salicylic acid, valdecoxib, ketoprofen, nimesulide and celecoxib in plasma by high-performance liquid chromatography with UV detection. | Biomedical chromatography : BMC 20060101 |
Monocyte chemoattractant protein 1 and macrophage cyclooxygenase 2 expression in colonic adenoma. | Gut 20060101 |
Gemcitabine plus celecoxib (GECO) in advanced pancreatic cancer: a phase II trial. | Cancer chemotherapy and pharmacology 20060101 |
Ultrastructural and immunohistochemical analysis of rat uroepithelial cell junctions after partial bladder outlet obstruction and selective COX-2 inhibitor treatment. | Acta histochemica 20060101 |
R(+)-methanandamide elicits a cyclooxygenase-2-dependent mitochondrial apoptosis signaling pathway in human neuroglioma cells. | Pharmaceutical research 20060101 |
Effects of cyclooxygenase-1 and -2 inhibition on gastric acid secretion and cardiovascular functions in rats. | Pharmacology 20060101 |
Combination celecoxib and temozolomide in C6 rat glioma orthotopic model. | Oncology reports 20060101 |
Differential direct effects of cyclo-oxygenase-1/2 inhibition on proteoglycan turnover of human osteoarthritic cartilage: an in vitro study. | Arthritis research & therapy 20060101 |
Lipopolysaccharide induces cyclooxygenase-2 in intestinal epithelium via a noncanonical p38 MAPK pathway. | Journal of immunology (Baltimore, Md. : 1950) 20060101 |
COX-2 selective drugs and cardiovascular risks: same data but discrepant conclusions? | Expert opinion on drug safety 20060101 |
Comparative cardiovascular safety of traditional nonsteroidal anti-inflammatory drugs. | Expert opinion on drug safety 20060101 |
More pronounced inhibition of cyclooxygenase 2, increase in blood pressure, and reduction of heart rate by treatment with diclofenac compared with celecoxib and rofecoxib. | Arthritis and rheumatism 20060101 |
Asthma attacks induced by low doses of celecoxib, aspirin, and acetaminophen. | The Journal of allergy and clinical immunology 20060101 |
Quantification of infant exposure to celecoxib through breast milk. | British journal of clinical pharmacology 20060101 |
Systematic review: coxibs, non-steroidal anti-inflammatory drugs or no cyclooxygenase inhibitors in gastroenterological high-risk patients? | Alimentary pharmacology & therapeutics 20060101 |
Prostanoid receptor EP1 and Cox-2 in injured human nerves and a rat model of nerve injury: a time-course study. | BMC neurology 20060101 |
Efficacy and safety of rofecoxib 12.5 mg and celecoxib 200 mg in two similarly designed osteoarthritis studies. | Current medical research and opinion 20060101 |
Celecoxib decreases Ki-67 proliferative index in active smokers. | Clinical cancer research : an official journal of the American Association for Cancer Research 20060101 |
The COX-2 story: is any drug completely 'safe?'. | Gastroenterology 20060101 |
Marked interindividual variability in the response to selective inhibitors of cyclooxygenase-2. | Gastroenterology 20060101 |
Erdheim-Chester's disease of the heart: a diagnostic conundrum and collision with the same mass in the orbit. | The heart surgery forum 20060101 |
The selective Cox-2 inhibitor Celecoxib suppresses angiogenesis and growth of secondary bone tumors: an intravital microscopy study in mice. | BMC cancer 20060101 |
Synthesis of 5-phenyl-1-(3-pyridyl)-1H-1,2,4-triazole-3-carboxylic acid derivatives of potential anti-inflammatory activity. | Archiv der Pharmazie 20060101 |
Chemoprevention of colorectal cancer with nonsteroidal anti-inflammatory drugs. | Chinese journal of digestive diseases 20060101 |
Importance of the EP(1) receptor in cutaneous UVB-induced inflammation and tumor development. | The Journal of investigative dermatology 20060101 |
Preventing chronic pain after surgery: who, how, and when? | Regional anesthesia and pain medicine 20060101 |
The effect of cyclooxygenase-2 inhibition on acute and chronic donor-site pain after spinal-fusion surgery. | Regional anesthesia and pain medicine 20060101 |
Postoperative pain scores and analgesic requirements after thyroid surgery: comparison of three intraoperative opioid regimens. | International journal of medical sciences 20060101 |
Resection and use of a cyclooxygenase-2 inhibitor for treatment of pancreatic adenocarcinoma in a cockatiel. | Journal of the American Veterinary Medical Association 20060101 |
Reduction in the risk of human breast cancer by selective cyclooxygenase-2 (COX-2) inhibitors. | BMC cancer 20060101 |
Topotecan is a substrate for multidrug resistance associated protein 4. | Current drug metabolism 20060101 |
First-dose analgesic effect of the cyclo-oxygenase-2 selective inhibitor lumiracoxib in osteoarthritis of the knee: a randomized, double-blind, placebo-controlled comparison with celecoxib [NCT00267215]. | Arthritis research & therapy 20060101 |
Selected science: an industry campaign to undermine an OSHA hexavalent chromium standard. | Environmental health : a global access science source 20060101 |
Cardiovascular events associated with long-term use of celecoxib, rofecoxib and meloxicam in Taiwan: an observational study. | Drug safety 20060101 |
Pancytopenia after low dose methotrexate therapy in a hemodialysis patient: case report and review of literature. | Renal failure 20060101 |
Coxibs and cardiovascular side-effects: from light to shadow. | Current pharmaceutical design 20060101 |
Patients, their doctors, nonsteroidal anti-inflammatory drugs and the perception of risk. | Arthritis research & therapy 20060101 |
Do coxibs reduce prescription of gastroprotective agents? Results of a record linkage study. | Cost effectiveness and resource allocation : C/E 20060101 |
Development of pulsatile systems for targeted drug delivery of celecoxib for prophylaxis of colorectal cancer. | Drug delivery 20060101 |
Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson's disease. | Journal of neuroinflammation 20060101 |
Cyclooxygenase expression is not required for release of arachidonic acid from cells by some nonsteroidal anti-inflammatory drugs and cancer preventive agents. | BMC pharmacology 20060101 |
The chrondoprotective actions of a natural product are associated with the activation of IGF-1 production by human chondrocytes despite the presence of IL-1beta. | BMC complementary and alternative medicine 20060101 |
Celecoxib induces regression of putative preneoplastic lesions in rat liver. | Anticancer research 20060101 |
Folate-targeted immunotherapy effectively treats established adjuvant and collagen-induced arthritis. | Arthritis research & therapy 20060101 |
Downregulation of survivin expression and concomitant induction of apoptosis by celecoxib and its non-cyclooxygenase-2-inhibitory analog, dimethyl-celecoxib (DMC), in tumor cells in vitro and in vivo. | Molecular cancer 20060101 |
Gene expression profiling of lymphoblastoid cell lines from monozygotic twins discordant in severity of autism reveals differential regulation of neurologically relevant genes. | BMC genomics 20060101 |
Anti-inflammatory and immunosuppressive drugs and reproduction. | Arthritis research & therapy 20060101 |
Prognostic significance of cyclooxygenase-2 (COX-2) expression in patients with surgically resectable adenocarcinoma of the oesophagus. | BMC cancer 20060101 |
Radiosensitizers in cervical cancer. Cisplatin and beyond. | Radiation oncology (London, England) 20060101 |
Combination of celecoxib with percutaneous radiotherapy in patients with localised prostate cancer - a phase I study. | Radiation oncology (London, England) 20060101 |
Cutaneous and intra-abdominal abscess formation in rats following radio frequency [corrected] ablation of liver tumors in combination with celecoxib treatment. | In vivo (Athens, Greece) 20060101 |
Accounting for the increase in NSAID expenditure: substitution or leakage? | Cost effectiveness and resource allocation : C/E 20060101 |
Omeprazole and misoprostol for preventing gastric mucosa effects caused by indomethacin and celecoxib in rats. | Acta cirurgica brasileira 20060101 |
Cell density influences the effect of celecoxib in two carcinoma cell lines. | Biotechnic & histochemistry : official publication of the Biological Stain Commission 20060101 |
Prophylaxis for pseudophakic cystoid macular oedema: a long way to go. | Clinical & experimental ophthalmology 20060101 |
Use of a cyclo-oxygenase 2 inhibitor for prophylaxis of cystoid macular oedema following cataract surgery: a randomized placebo-controlled trial. | Clinical & experimental ophthalmology 20060101 |
Effects of the selective cyclooxygenase-2 inhibitor analgesic celecoxib on renal carbonic anhydrase enzyme activity: a randomized, controlled trial. | American journal of therapeutics 20060101 |
Human pregnancy safety for agents used to treat rheumatoid arthritis: adequacy of available information and strategies for developing post-marketing data. | Arthritis research & therapy 20060101 |
Blood pressure effects of COX-2 inhibitors. | Journal of cardiovascular pharmacology 20060101 |
Expectations from patients with rheumatoid arthritis regarding COX-2s: cutting to the heart of the matter. | Journal of cardiovascular pharmacology 20060101 |
Rofecoxib increases susceptibility of human LDL and membrane lipids to oxidative damage: a mechanism of cardiotoxicity. | Journal of cardiovascular pharmacology 20060101 |
Integration of chemotherapy into current treatment strategies for brain metastases from solid tumors. | Radiation oncology (London, England) 20060101 |
Does celecoxib potentiate the anticoagulant effect of warfarin? A randomized, double-blind, controlled trial. | The Annals of pharmacotherapy 20060101 |
Increase in nonfatal digestive perforations and haemorrhages following introduction of selective NSAIDs: a public health concern. | Drug safety 20060101 |
Temporal relationship between use of NSAIDs, including selective COX-2 inhibitors, and cardiovascular risk. | Drug safety 20060101 |
The inflammatory process of gout and its treatment. | Arthritis research & therapy 20060101 |
COX-2 inhibitors celecoxib and rofecoxib prevent oxidative DNA fragmentation. | Anticancer research 20060101 |
Inhibition of cyclooxygenase-2 decreases breast cancer cell motility, invasion and matrix metalloproteinase expression. | BMC cancer 20060101 |
Cyclo-oxygenase-2 (Cox-2) expression and resistance to platinum versus platinum/paclitaxel containing chemotherapy in advanced ovarian cancer. | BMC cancer 20060101 |
COX-inhibitors relieve the immunosuppressive effect of tumor cells and improve functions of immune effectors. | International journal of immunopathology and pharmacology 20060101 |
MUC1 alters oncogenic events and transcription in human breast cancer cells. | Breast cancer research : BCR 20060101 |
Serious skin reactions and selective COX-2 inhibitors: a case series from prescription-event monitoring in England. | Drug safety 20060101 |
Antiangiogenic effect of sulindac sulfide could be secondary to induction of apoptosis and cell cycle arrest. | Anticancer research 20060101 |
Inhibition of large intestinal cancers by celecoxib using a serial sacrifice technique. | In vivo (Athens, Greece) 20060101 |
C-reactive protein (CRP)-lowering agents. | Cardiovascular drug reviews 20060101 |
Effects of dexamethasone and celecoxib on calcium homeostasis and expression of cyclooxygenase-2 mRNA in MG-63 human osteosarcoma cells. | Clinical and experimental rheumatology 20060101 |
Induction of cell cycle changes and modulation of apoptogenic/anti-apoptotic and extracellular signaling regulatory protein expression by water extracts of I'm-Yunity (PSP). | BMC complementary and alternative medicine 20060101 |
How direct-to-consumer television advertising for osteoarthritis drugs affects physicians' prescribing behavior. | Health affairs (Project Hope) 20060101 |
[Problems of cardiovascular toxicity of coxibs and non-selective NSA]. | Vnitrni lekarstvi 20060101 |
Cardioprotective aspirin users and their excess risk of upper gastrointestinal complications. | BMC medicine 20060101 |
Risk of acute myocardial infarction with nonselective non-steroidal anti-inflammatory drugs: a meta-analysis. | Arthritis research & therapy 20060101 |
[Clinical pharmacogenomics for CYP2C8 and CYP2C9: general concepts and application to the use of NSAIDs]. | Farmacia hospitalaria : organo oficial de expresion cientifica de la Sociedad Espanola de Farmacia Hospitalaria 20060101 |
Celecoxib decreases prostaglandin E2 concentrations in nipple aspirate fluid from high risk postmenopausal women and women with breast cancer. | BMC cancer 20060101 |
Nonsteroidal anti-inflammatory drugs (NSAIDs), cyxlooxygenase-2 selective inhibitors (coxibs) and gastrointestinal harm: review of clinical trials and clinical practice. | BMC musculoskeletal disorders 20060101 |
Acetylsalicylic acid as an adjuvant therapy for schizophrenia. | Trials 20060101 |
Evaluation of anti-inflammatory and analgesic activity of a new class of biphenyl analogs in animal models of inflammation. | Arzneimittel-Forschung 20060101 |
Impact of rofecoxib withdrawal on cyclooxygenase-2 utilization among patients with and without cardiovascular risk. | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20060101 |
A celecoxib derivative potently inhibits proliferation of colon adenocarcinoma cells by induction of apoptosis. | Anticancer research 20060101 |
A novel copper complex induces ROS generation in doxorubicin resistant Ehrlich ascitis carcinoma cells and increases activity of antioxidant enzymes in vital organs in vivo. | BMC cancer 20060101 |
Exogenous glucosamine globally protects chondrocytes from the arthritogenic effects of IL-1beta. | Arthritis research & therapy 20060101 |
Effects of non steroidal anti-inflammatory drugs on the antioxidant defense system and the membrane functions in the rat intestine. | Nutricion hospitalaria 20060101 |
Photodynamic therapy and tumor imaging of hypericin-treated squamous cell carcinoma. | World journal of surgical oncology 20060101 |
Meloxicam tolerance in hypersensitivity to nonsteroidal anti-inflammatory drugs. | Journal of investigational allergology & clinical immunology 20060101 |
Use of nonsteroidal anti-inflammatory drugs in patients with aspirin hypersensitivity : safety of cyclo-oxygenase-2 inhibitors. | Treatments in respiratory medicine 20060101 |
A novel role for cyclooxygenase-2 in regulating vascular channel formation by human breast cancer cells. | Breast cancer research : BCR 20060101 |
Initial experience with stapled hemorrhoidopexy for treatment of hemorrhoids. | Arquivos de gastroenterologia 20060101 |
Celecoxib versus a non-selective NSAID plus proton-pump inhibitor: what are the considerations? | Journal of pain & palliative care pharmacotherapy 20060101 |
A comparative study on the cost of new antibiotics and drugs of other therapeutic categories. | PloS one 20060101 |
COX-2 inhibitor celecoxib suppresses tumor growth and lung metastasis of a murine mammary cancer. | Anticancer research 20060101 |
Ligand-based design, synthesis and primary in vivo screening of pyrrole derivatives as potential tricyclic anti-inflammatory agents. | Arzneimittel-Forschung 20060101 |
Celecoxib and curcumin additively inhibit the growth of colorectal cancer in a rat model. | Digestion 20060101 |
Association of hypogammaglobulinemia with DRESS (Drug Rash with Eosinophilia and Systemic Symptoms). | European journal of dermatology : EJD 20060101 |
Adverse cutaneous reactions to selective cyclooxygenase 2 inhibitors: experience of an Italian drug-surveillance center. | Journal of cutaneous medicine and surgery 20060101 |
Celecoxib inhibits Cdx2 expression and prevents gastric cancer in Helicobacter pylori-infected Mongolian gerbils. | Digestion 20060101 |
Tumor necrosis factor-alpha in temporomandibular joint synovial fluid predicts treatment effects on pain by intra-articular glucocorticoid treatment. | Mediators of inflammation 20060101 |
Exploring effects of different nonsteroidal antiinflammatory drugs on malondialdehyde profile. | Acta poloniae pharmaceutica 20060101 |
Celecoxib reduces narcotic use and pain following augmentation mammaplasty. | Aesthetic surgery journal 20060101 |
A case of intranasal meningocele. | McGill journal of medicine : MJM : an international forum for the advancement of medical sciences by students 20060101 |
C-reactive Protein in Patients with Metastatic Clear Cell Renal Carcinoma: An Important Biomarker for Tumor-associated Inflammation. | Biomarker insights 20060101 |
[Effect of short-term nonsteroidal antiinflammatory therapy on mean blood pressure. A prospective, randomized clinical trial]. | Reumatologia clinica 20060101 |
What clinical pharmacology means to us. | Mens sana monographs 20060101 |
Cardiac hypertrophy induced by prostaglandin F(2alpha) may be mediated by calcineurin signal transduction pathway in rats. | Sheng li xue bao : [Acta physiologica Sinica] 20051225 |
Drug testing. Massive trial of Celebrex seeks to settle safety concerns. | Science (New York, N.Y.) 20051223 |
Risk of gastrointestinal effects with COX-2 inhibitors and NSAIDs: study conclusions do not reflect findings for celecoxib. | BMJ (Clinical research ed.) 20051217 |
Risk of gastrointestinal effects with COX-2 inhibitors and NSAIDs: what does evidence from randomised trials show about celecoxib? | BMJ (Clinical research ed.) 20051217 |
Multitarget inhibition of drug-resistant multiple myeloma cell lines by dimethyl-celecoxib (DMC), a non-COX-2 inhibitory analog of celecoxib. | Blood 20051215 |
Helicobacter pylori-Induced invasion and angiogenesis of gastric cells is mediated by cyclooxygenase-2 induction through TLR2/TLR9 and promoter regulation. | Journal of immunology (Baltimore, Md. : 1950) 20051215 |
Antitumor efficacy of capecitabine and celecoxib in irradiated and lead-shielded, contralateral human BxPC-3 pancreatic cancer xenografts: clinical implications of abscopal effects. | Clinical cancer research : an official journal of the American Association for Cancer Research 20051215 |
Risk of adverse gastrointestinal outcomes in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis. | BMJ (Clinical research ed.) 20051203 |
A phase I trial of celecoxib in combination with docetaxel and irinotecan in patients with advanced cancer. | Cancer chemotherapy and pharmacology 20051201 |
A phase II study of celecoxib, gemcitabine, and cisplatin in advanced pancreatic cancer. | Investigational new drugs 20051201 |
Design, synthesis, and biological evaluation of linear 1-(4-, 3- or 2-methylsulfonylphenyl)-2-phenylacetylenes: a novel class of cyclooxygenase-2 inhibitors. | Bioorganic & medicinal chemistry 20051201 |
Cloning, expression, and functional characterization of human cyclooxygenase-1 splicing variants: evidence for intron 1 retention. | The Journal of pharmacology and experimental therapeutics 20051201 |
Modification of eicosanoid profile in human blood treated by dual COX/LOX inhibitors. | Prostaglandins, leukotrienes, and essential fatty acids 20051201 |
Chemopreventive agent-induced modulation of death receptors. | Apoptosis : an international journal on programmed cell death 20051201 |
A new method of oral drug provocation testing for determining safe alternatives for patients with non-steroidal anti-inflammatory drug intolerance: the triple test. | International archives of allergy and immunology 20051201 |
Efficacy of COX-2 inhibitors in a case of congenital nephrogenic diabetes insipidus. | Pediatric nephrology (Berlin, Germany) 20051201 |
Anti-angiogenic effects of Hypericin-photodynamic therapy in combination with Celebrex in the treatment of human nasopharyngeal carcinoma. | International journal of molecular medicine 20051201 |
The influence of Celecoxib on matrix synthesis by chondrocytes under mechanical stress in vitro. | International journal of molecular medicine 20051201 |
Evaluation of 2 celecoxib derivatives: analgesic effect and selectivity to cyclooxygenase-2/1. | Acta pharmacologica Sinica 20051201 |
An animal model of calcium oxalate urolithiasis based on a cyclooxygenase 2 selective inhibitor. | Urological research 20051201 |
Response of refractory osteosarcoma to thalidomide and celecoxib. | The Lancet. Oncology 20051201 |
Neoadjuvant selective COX-2 inhibition down-regulates important oncogenic pathways in patients with esophageal adenocarcinoma. | Annals of surgery 20051201 |
Selective cyclooxygenase-2 inhibition produces heterogeneous erythema response to ultraviolet irradiation. | The Journal of investigative dermatology 20051201 |
Simultaneous targeting of the epidermal growth factor receptor and cyclooxygenase-2 pathways for pancreatic cancer therapy. | Molecular cancer therapeutics 20051201 |
Celebrex offers a small protection from root resorption associated with orthodontic movement. | Journal of the California Dental Association 20051201 |
Prolonged cholestasis associated with short-term use of celecoxib. | Gastroenterologie clinique et biologique 20051201 |
[Acute colitis closely following the beginning of celecoxib treatment]. | Gastroenterologie clinique et biologique 20051201 |
Inhibition of prostaglandin F(2alpha) by selective cyclooxygenase 2 inhibitors accounts for reduced rat leukocyte migration. | Inflammation 20051201 |
Management of oxaliplatin-induced peripheral neuropathy. | Therapeutics and clinical risk management 20051201 |
Discrepancy between effects of milligram and nanogram doses of a COX-2 inhibitor (celecoxib) on morphine state-dependent memory of passive avoidance in mice. | Brain research bulletin 20051130 |
[Do selective COX-2 inhibitors have adverse renal and cardiovascular effects?]. | Praxis 20051123 |
Resolution of inflammation: prostaglandin E2 dissociates nuclear trafficking of individual NF-kappaB subunits (p65, p50) in stimulated rheumatoid synovial fibroblasts. | Journal of immunology (Baltimore, Md. : 1950) 20051115 |
In vitro and in vivo effects and mechanisms of celecoxib-induced growth inhibition of human hepatocellular carcinoma cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20051115 |
Front-line paclitaxel and irinotecan combination chemotherapy in advanced non-small-cell lung cancer: a phase I-II trial. | British journal of cancer 20051114 |
Extraction and visualization of potential pharmacophore points using support vector machines: application to ligand-based virtual screening for COX-2 inhibitors. | Journal of medicinal chemistry 20051103 |
Impact of CYP2C9 genotype on pharmacokinetics: are all cyclooxygenase inhibitors the same? | Drug metabolism and disposition: the biological fate of chemicals 20051101 |
Human multidrug resistance associated protein 4 confers resistance to camptothecins. | Pharmaceutical research 20051101 |
Post-training intrahippocampal infusion of nicotine prevents spatial memory retention deficits induced by the cyclo-oxygenase-2-specific inhibitor celecoxib in rats. | Journal of neurochemistry 20051101 |
Inflammatory mechanisms underlying the rat pulmonary neutrophil influx induced by airway exposure to staphylococcal enterotoxin type A. | British journal of pharmacology 20051101 |
Celecoxib inhibits urokinase-type plasminogen activator (uPA) production in MDA-MB-231 breast cancer cells. | Breast cancer research and treatment 20051101 |
Cyclooxygenase-2 inhibitors. | Current opinion in gastroenterology 20051101 |
Effects of specific COX-2-inhibition on renin release and renal and systemic prostanoid synthesis in healthy volunteers. | Kidney international 20051101 |
Expression of COX-2 mRNA in peripheral blood monocytes from patients with acute myocardial infarction and its significance. | Clinical chemistry 20051101 |
A real time quantitative PCR analysis and correlation of COX-1 and COX-2 enzymes in inflamed dental pulps following administration of three different NSAIDs. | Journal of endodontics 20051101 |
Celecoxib and cardiovascular risks. | Expert opinion on drug safety 20051101 |
Dimethyl celecoxib as a novel non-cyclooxygenase 2 therapy in the treatment of non-small cell lung cancer. | The Journal of thoracic and cardiovascular surgery 20051101 |
Avoiding glucocorticoid administration in a neurooncological case. | Cancer biology & therapy 20051101 |
Circadian pattern of spontaneous behavior in monarthritic rats: a novel global approach to evaluation of chronic pain and treatment effectiveness. | Arthritis and rheumatism 20051101 |
Celecoxib compared with lansoprazole and naproxen to prevent gastrointestinal ulcer complications. | The American journal of medicine 20051101 |
Cyclooxygenase-2 inhibitory phenylbutenoids from the rhizomes of Zingiber cassumunar. | Chemical & pharmaceutical bulletin 20051101 |
A feasibility trial of antiangiogenic (metronomic) chemotherapy in pediatric patients with recurrent or progressive cancer. | Journal of pediatric hematology/oncology 20051101 |
Celecoxib approved for pain relief for AS. | Health news (Waltham, Mass.) 20051101 |
Cardiovascular issues of COX-2 inhibitors and NSAIDs. | Australian family physician 20051101 |
Pharmacokinetic interactions of the oral renin inhibitor aliskiren with lovastatin, atenolol, celecoxib and cimetidine. | International journal of clinical pharmacology and therapeutics 20051101 |
Ternary amorphous composites of celecoxib, poly(vinyl pyrrolidone) and meglumine with enhanced solubility. | Die Pharmazie 20051101 |
Clinical Questions #6. Does celecoxib increase cardiovascular risk? | WMJ : official publication of the State Medical Society of Wisconsin 20051101 |
[Innovation of anti-inflammatory drugs--inhibition of cyclooxygenases]. | Yao xue xue bao = Acta pharmaceutica Sinica 20051101 |
[Atorvastatin reduces the expression of COX-2 mRNA in peripheral blood monocytes in patients with acute myocardial infarction and modulates the early inflammatory response]. | Zhonghua xin xue guan bing za zhi 20051101 |
The cardiovascular safety of celecoxib. | Future cardiology 20051101 |
Molecular targets of dietary polyphenols with anti-inflammatory properties. | Yonsei medical journal 20051031 |
Overexpression of cyclooxygenase-2 in human HepG2, Bel-7402 and SMMC-7721 hepatoma cell lines and mechanism of cyclooxygenase-2 selective inhibitor celecoxib-induced cell growth inhibition and apoptosis. | World journal of gastroenterology 20051028 |
[Natural substances and pharmaceutical preparations can prevent cancer. Chemoprevention instead of chemotherapy]. | MMW Fortschritte der Medizin 20051027 |
NSAIDs in neuroblastoma therapy. | Cancer letters 20051018 |
Allellic variants in regulatory regions of cyclooxygenase-2: association with advanced colorectal adenoma. | British journal of cancer 20051017 |
Celecoxib and NS-398 enhance photodynamic therapy by increasing in vitro apoptosis and decreasing in vivo inflammatory and angiogenic factors. | Cancer research 20051015 |
Radiosensitivity enhancement by celecoxib, a cyclooxygenase (COX)-2 selective inhibitor, via COX-2-dependent cell cycle regulation on human cancer cells expressing differential COX-2 levels. | Cancer research 20051015 |
Coxibs and cardiovascular risk. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20051011 |
Going against the flow: the impact of PHARMAC not funding COX-2 inhibitors for chronic arthritis. | The New Zealand medical journal 20051007 |
Cancer chemoprevention: lessons learned and future directions. | British journal of cancer 20051003 |
Cyclooxygenase inhibitors modulate NK activities that control metastatic disease. | Cancer immunology, immunotherapy : CII 20051001 |
Celecoxib, a cyclooxygenase-2 inhibitor, prevents induction of liver preneoplastic lesions in rats. | Journal of hepatology 20051001 |
Ethyl caffeate suppresses NF-kappaB activation and its downstream inflammatory mediators, iNOS, COX-2, and PGE2 in vitro or in mouse skin. | British journal of pharmacology 20051001 |
Nitric oxide induces apoptosis via AP-1-driven upregulation of COX-2 in rat pheochromocytoma cells. | Free radical biology & medicine 20051001 |
Bleeding complications in patients on celecoxib and warfarin. | Journal of clinical pharmacy and therapeutics 20051001 |
Chemoprophylaxis of colon cancer. | Current gastroenterology reports 20051001 |
Inhibition of DNA repair as a mechanism of enhanced radioresponse of head and neck carcinoma cells by a selective cyclooxygenase-2 inhibitor, celecoxib. | International journal of radiation oncology, biology, physics 20051001 |
Phase I study of gefitinib plus celecoxib in recurrent or metastatic squamous cell carcinoma of the head and neck. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20051001 |
Antimutagenic and anti-oxidant activities of the non-steroidal anti-inflammatory drug celecoxib. | Clinical and experimental pharmacology & physiology 20051001 |
Low direct cytotoxicity and cytoprotective effects of nitric oxide releasing indomethacin. | Digestive diseases and sciences 20051001 |
Prescriptions for chronic high-dose cyclooxygenase-2 inhibitors are often inappropriate and potentially dangerous. | Journal of general internal medicine 20051001 |
The role of cyclooxygenase-2 in mediating the effects of histamine on cell proliferation and vascular endothelial growth factor production in colorectal cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20051001 |
Celecoxib does not affect osteointegration of cementless total hip stems. | The Journal of arthroplasty 20051001 |
[A case report of chemotherapy with thalidomide, celecoxib and gemcitabine in the treatment of patients with brain metastases from lung cancer]. | No shinkei geka. Neurological surgery 20051001 |
Does celecoxib use increase the risk of cardiovascular events? | Gastroenterology 20051001 |
Selective cyclooxygenase-2 inhibitors from Calophyllum membranaceum. | Journal of natural products 20051001 |
Differential molecular interactions between the crystalline and the amorphous phases of celecoxib. | The Journal of pharmacy and pharmacology 20051001 |
Celecoxib still on the market: but for whose benefit? | Prescrire international 20051001 |
[Celecoxib-induced aquagenic keratoderma]. | Actas dermo-sifiliograficas 20051001 |
Celecoxib induces dose dependent growth inhibition in nasopharyngeal carcinoma cell lines independent of cyclooxygenase-2 expression. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20051001 |
Curcumin synergistically potentiates the growth inhibitory and pro-apoptotic effects of celecoxib in pancreatic adenocarcinoma cells. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20051001 |
Current directions for COX-2 inhibition in breast cancer. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20051001 |
Cyclooxygenase-2 inhibitors suppress angiogenesis and growth of gastric cancer xenografts. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20051001 |
Cytostatic and cytotoxic effects of cyclooxygenase inhibitors and their synergy with docosahexaenoic acid on the growth of human skin melanoma A-375 cells. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20051001 |
Study of COX-2, Ki67, and p53 expression to predict effectiveness of 5-flurouracil, epirubicin and cyclophosphamide with celecoxib treatment in breast cancer patients. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20051001 |
Serum lipid profiles in patients receiving endocrine treatment for breast cancer--the results from the Celecoxib Anti-Aromatase Neoadjuvant (CAAN) Trial. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20051001 |
Taxanes and COX-2 inhibitors: from molecular pathways to clinical practice. | Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 20051001 |
CC 05, a novel anti-inflammatory compound, exerts its effect by inhibition of cyclooxygenase-2 activity. | European journal of pharmacology 20050927 |
Cyclo-oxygenase-2 expression and prostaglandin E2 production in experimental chronic gastric ulcer healing. | European journal of pharmacology 20050920 |
An overview of the recent developments in analytical methodologies for determination of COX-2 inhibitors in bulk drugs, pharmaceuticals and biological matrices. | Journal of pharmaceutical and biomedical analysis 20050915 |
Targeting cyclooxygenase-2 in recurrent non-small cell lung cancer: a phase II trial of celecoxib and docetaxel. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050915 |
Celecoxib and curcumin synergistically inhibit the growth of colorectal cancer cells. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050915 |
Does the pro-hypertensive effect of cyclooxygenase-2 inhibitors account for the increased risk in cardiovascular disease? | The American journal of cardiology 20050915 |
Carbonic anhydrase inhibitors: stacking with Phe131 determines active site binding region of inhibitors as exemplified by the X-ray crystal structure of a membrane-impermeant antitumor sulfonamide complexed with isozyme II. | Journal of medicinal chemistry 20050908 |
Involvement of intracellular Ca2+ levels in nonsteroidal anti-inflammatory drug-induced apoptosis. | The Journal of biological chemistry 20050902 |
Connexin43 is overexpressed in Apc(Min/+)-mice adenomas and colocalises with COX-2 in myofibroblasts. | International journal of cancer 20050901 |
In vitro antiproliferative activity against human colon cancer cell lines of representative 4-thiazolidinones. Part I. | Bioorganic & medicinal chemistry letters 20050901 |
Feasibility of performing chemoprevention trials in women at elevated risk of ovarian carcinoma: initial examination of celecoxib as a chemopreventive agent. | Gynecologic oncology 20050901 |
Combination of cyclooxygenase-2 inhibitors and oxaliplatin increases the growth inhibition and death in human colon cancer cells. | Biochemical pharmacology 20050901 |
Sulfotransferase 2A1 forms estradiol-17-sulfate and celecoxib switches the dominant product from estradiol-3-sulfate to estradiol-17-sulfate. | The Journal of steroid biochemistry and molecular biology 20050901 |
How celecoxib could be safer, how valdecoxib might have been. | The Annals of pharmacotherapy 20050901 |
Cross-talk between cyclooxygenase-2 and epidermal growth factor receptor in non-small cell lung cancer. | Lung cancer (Amsterdam, Netherlands) 20050901 |
Effects of celecoxib in human retinoblastoma cell lines and in a transgenic murine model of retinoblastoma. | The British journal of ophthalmology 20050901 |
Preoperative use of selective COX-II inhibitors for pain management in laparoscopic nissen fundoplication. | Surgical endoscopy 20050901 |
COX-2 inhibitors and arterial hypertension: an analysis of spontaneous case reports in the Pharmacovigilance database. | European journal of clinical pharmacology 20050901 |
Low direct cytotoxicity of nabumetone on gastric mucosal cells. | Digestive diseases and sciences 20050901 |
Blood-nourishing and hard-softening capsule costs less in the management of osteoarthritic knee pain: a randomized controlled trial. | Evidence-based complementary and alternative medicine : eCAM 20050901 |
Prevention of colon cancer by low doses of celecoxib, a cyclooxygenase inhibitor, administered in diet rich in omega-3 polyunsaturated fatty acids. | Cancer research 20050901 |
Randomized, placebo-controlled, esophageal squamous cell cancer chemoprevention trial of selenomethionine and celecoxib. | Gastroenterology 20050901 |
Combined targeting of the epidermal growth factor receptor and cyclooxygenase-2 pathways. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050901 |
Epidermal growth factor-induced cyclooxygenase-2 expression is mediated through phosphatidylinositol-3 kinase, not mitogen-activated protein/extracellular signal-regulated kinase kinase, in recurrent respiratory papillomas. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050901 |
Tumor growth inhibition by simultaneously blocking epidermal growth factor receptor and cyclooxygenase-2 in a xenograft model. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050901 |
Cytochrome P450 2C9 genotype: impact on celecoxib safety and pharmacokinetics in a pediatric patient. | Clinical pharmacology and therapeutics 20050901 |
The Vioxx debacle revisited. | The American journal of medicine 20050901 |
Cyclooxygenase-independent down-regulation of multidrug resistance-associated protein-1 expression by celecoxib in human lung cancer cells. | Molecular cancer therapeutics 20050901 |
[COX-2 inhibitors in cancer prevention]. | Revista clinica espanola 20050901 |
[Cardiovascular events: a class effect by COX-2 inhibitors]. | Arquivos brasileiros de cardiologia 20050901 |
Nonsteroidal anti-inflammatory drugs: confusion, controversy and dental implications. | Journal (Canadian Dental Association) 20050901 |
Synergistic tumoricidal effect between celecoxib and adenoviral-mediated delivery of mda-7 in human breast cancer cells. | Surgery 20050901 |
A new stability--indicating RP-HPLC method to determine assay and known impurity of Celecoxib API. | Drug development and industrial pharmacy 20050901 |
Ubiquitous expression of cyclooxygenase-2 in meningiomas and decrease in cell growth following in vitro treatment with the inhibitor celecoxib: potential therapeutic application. | Journal of neurosurgery 20050901 |
The use and safety profile of non-steroidal antiinflammatory drugs among Turkish patients with osteoarthritis. | The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology 20050901 |
Calotropis procera latex-induced inflammatory hyperalgesia--effect of antiinflammatory drugs. | Mediators of inflammation 20050831 |
Transcriptional induction of cyclooxygenase-2 in osteoclast precursors is involved in RANKL-induced osteoclastogenesis. | Blood 20050815 |
Need for common internal controls when assessing the relative efficacy of pharmacologic agents using a meta-analytic approach: case study of cyclooxygenase 2-selective inhibitors for the treatment of osteoarthritis. | Arthritis and rheumatism 20050815 |
[The efficacy of selective Cox-2-inhibitors in comparison with conventional NSAIDs]. | MMW Fortschritte der Medizin 20050804 |
A novel celecoxib derivative potently induces apoptosis of human synovial fibroblasts. | The Journal of pharmacology and experimental therapeutics 20050801 |
Cyclooxygenase-2 inhibitors decrease vascular endothelial growth factor expression in colon cancer cells by enhanced degradation of Sp1 and Sp4 proteins. | Molecular pharmacology 20050801 |
Targeting the beta-catenin/APC pathway: a novel mechanism to explain the cyclooxygenase-2-independent anticarcinogenic effects of celecoxib in human colon carcinoma cells. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050801 |
Effects of selective COX-2 and 5-LOX inhibition on prostaglandin and leukotriene synthesis in ductal pancreatic cancer in Syrian hamster. | Prostaglandins, leukotrienes, and essential fatty acids 20050801 |
The molecular basis for coxib inhibition of p38alpha MAP kinase. | Bioorganic & medicinal chemistry letters 20050801 |
Celecoxib inhibits ureteral contractility and prostanoid release. | The Journal of urology 20050801 |
Is COX-2 a perpetrator or a protector? Selective COX-2 inhibitors remain controversial. | Acta pharmacologica Sinica 20050801 |
Neuroprotective effects of cyclooxygenase-2 inhibitor celecoxib against toxicity of LPS-stimulated macrophages toward motor neurons. | Acta pharmacologica Sinica 20050801 |
Is COX-2 a 'collateral' target in cancer prevention? | Biochemical Society transactions 20050801 |
Drug intervention can correct subnormal retinal oxygenation response in experimental diabetic retinopathy. | Investigative ophthalmology & visual science 20050801 |
A multicenter phase II trial of thalidomide and celecoxib for patients with relapsed and refractory multiple myeloma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050801 |
Killing pain, not neurons. | Nature medicine 20050801 |
Update on cyclooxygenase inhibitors: has a third COX isoform entered the fray? | Current medical research and opinion 20050801 |
Oncogenic potential of MEK1 in rat intestinal epithelial cells is mediated via cyclooxygenase-2. | Gastroenterology 20050801 |
PSA and clinical responses to celecoxib in a patient with prostate cancer and bone metastases. | Mayo Clinic proceedings 20050801 |
Role of aromatase inhibitors in breast cancer. | British journal of cancer 20050801 |
Potential use of COX-2-aromatase inhibitor combinations in breast cancer. | British journal of cancer 20050801 |
Sequencing of aromatase inhibitors. | British journal of cancer 20050801 |
[A COX-2 inhibitor suppresses esophageal inflammation-metaplasia-adenocarcinoma sequence in rats]. | Nihon rinsho. Japanese journal of clinical medicine 20050801 |
Role of COX-2 selective inhibitors for prevention and treatment of cancer. | Die Pharmazie 20050801 |
Thrombosis and priapism in a patient with Henoch-Schonlein purpura. | Rheumatology international 20050801 |
Safety of etoricoxib, a new cyclooxygenase 2 inhibitor, in patients with nonsteroidal anti-inflammatory drug-induced urticaria and angioedema. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050801 |
Plasma pharmacokinetics and synovial fluid concentrations after oral administration of single and multiple doses of celecoxib in greyhounds. | American journal of veterinary research 20050801 |
Simultaneous determination of rofecoxib and celecoxib in human plasma by high-performance liquid chromatography. | Journal of chromatographic science 20050801 |
[Significance and expression of cyclooxygenase-2 mRNA in peripheral blood monocytes in patients with acute coronary syndrome]. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20050801 |
Cardiovascular safety of lumiracoxib: a meta-analysis of all randomized controlled trials > or =1 week and up to 1 year in duration of patients with osteoarthritis and rheumatoid arthritis. | Clinical therapeutics 20050801 |
Could the combination of celecoxib and 4HPR be an effective lung cancer treatment? | Cancer biology & therapy 20050801 |
[Therapeutic strategies using VEGF inhibitors in colorectal cancer]. | Bulletin du cancer 20050801 |
PGE2 produced by lung cancer suppresses immune function through T-regulatory cells and can be blocked by the COX2 inhibitor Celebrex. | Cancer biology & therapy 20050801 |
SKI306X, an oriental herbal mixture, suppresses gastric leukotriene B4 synthesis without causing mucosal injury and the diclofenac-induced gastric lesions. | Life sciences 20050729 |
Antitumoral effect of celecoxib in hepatocellular carcinoma. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20050720 |
[The role of hypoxia on expression of cyclooxygenase-2 in synovial fibroblasts derived from human temporomandular joint]. | Zhonghua yi xue za zhi 20050706 |
A regional audit of the use of COX-2 selective non-steroidal anti-inflammatory drugs (NSAIDs) in rheumatology clinics in the West Midlands, in relation to NICE guidelines. | Rheumatology (Oxford, England) 20050701 |
Selective cyclooxygenase (COX) inhibition causes damage to portal hypertensive gastric mucosa: roles of nitric oxide and NF-kappaB. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20050701 |
Safety of short-term administration of celecoxib in decompensated cirrhosis. | Hepatology (Baltimore, Md.) 20050701 |
Licofelone, a novel 5-LOX/COX-inhibitor, attenuates leukocyte rolling and adhesion on endothelium under flow. | Biochemical pharmacology 20050701 |
Preparation of celecoxib-dimethyl-beta-cyclodextrin inclusion complex: characterization and in vitro permeation study. | European journal of medicinal chemistry 20050701 |
Fibroblasts express RANKL and support osteoclastogenesis in a COX-2-dependent manner after stimulation with titanium particles. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20050701 |
The cardiovascular toxicity of selective and nonselective cyclooxygenase inhibitors: comparisons, contrasts, and aspirin confounding. | Journal of clinical pharmacology 20050701 |
Design, synthesis, and anti-inflammatory evaluation of a series of novel amino acid-binding 1,5-diarylpyrazole derivatives. | Acta pharmacologica Sinica 20050701 |
Prevention of intra-abdominal adhesions using the antiangiogenic COX-2 inhibitor celecoxib. | Annals of surgery 20050701 |
Non-steroidal anti-inflammatory drugs (NSAIDs) and other anti-inflammatory agents in the treatment of neurodegenerative disease. | Current Alzheimer research 20050701 |
Selection of topically applied non-steroidal anti-inflammatory drugs for oral cancer chemoprevention. | Oral oncology 20050701 |
Neovascularization and neoinnervation of subcutaneously placed nucleus pulposus and the inhibitory effects of certain drugs. | Spine 20050701 |
Celecoxib is often combined with cytochrome P450 2D6 substrates in general clinical practice. | Clinical pharmacology and therapeutics 20050701 |
Pulmonary embolism in a woman taking oral contraceptives and valdecoxib. | PLoS medicine 20050701 |
T-cell lymphopenia associated with infliximab and cyclophosphamide. | The American journal of the medical sciences 20050701 |
A Thrombelastograph whole blood assay for clinical monitoring of NSAID-insensitive transcellular platelet activation by arachidonic acid. | The Journal of laboratory and clinical medicine 20050701 |
Spectral markers in preneoplastic intestinal mucosa: an accurate predictor of tumor risk in the MIN mouse. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20050701 |
Effect of concomitant polyethylene glycol and celecoxib on colonic aberrant crypt foci and tumors in F344 rats. | Digestive diseases and sciences 20050701 |
Comparative gastrointestinal toxicity of selective cyclooxygenase (COX-2) inhibitors. | Indian journal of experimental biology 20050701 |
Long-term use and tolerability of cyclooxygenase-2 inhibitors in patients with analgesic intolerance. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20050701 |
The furoxan system: design of selective nitric oxide (NO) donor inhibitors of COX-2 endowed with anti-aggregatory and vasodilating activities. | Chemistry & biodiversity 20050701 |
Inconsistency in the editorial process in Archives of Internal Medicine? | Archives of internal medicine 20050627 |
Tailoring arthritis therapy in the wake of the NSAID crisis. | The New England journal of medicine 20050623 |
Cardiovascular risk associated with celecoxib. | The New England journal of medicine 20050623 |
Cyclooxygenase-2 inhibitor celecoxib augments chemotherapeutic drug-induced apoptosis by enhancing activation of caspase-3 and -9 in prostate cancer cells. | International journal of cancer 20050620 |
Anti-proliferative and apoptotic effects of celecoxib on human chronic myeloid leukemia in vitro. | Cancer letters 20050616 |
Beta-amyloid-induced apoptosis is associated with cyclooxygenase-2 up-regulation via the mitogen-activated protein kinase-NF-kappaB signaling pathway. | Free radical biology & medicine 20050615 |
Celecoxib augmentation of continuously ill patients with schizophrenia. | Biological psychiatry 20050615 |
Risk of myocardial infarction in patients taking cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs: population based nested case-control analysis. | BMJ (Clinical research ed.) 20050611 |
Differences in outcomes of patients with congestive heart failure prescribed celecoxib, rofecoxib, or non-steroidal anti-inflammatory drugs: population based study. | BMJ (Clinical research ed.) 20050611 |
Combining exercise and cyclooxygenase-2 inhibition does not ameliorate learning deficits after brain insult, despite an increase in BDNF levels. | Brain research 20050607 |
[Selective cyclooxygenase-2 inhibitors. A population-based analysis of use in France over a three-year period and comparison with randomised clinical trials]. | Presse medicale (Paris, France : 1983) 20050604 |
3-[4-(methylsulfonyl)phenyl]-5-(trifluoromethyl)(2-pyridyl) phenyl ketone as a potent and orally active cyclooxygenase-2 selective inhibitor: synthesis and biological evaluation. | Journal of medicinal chemistry 20050602 |
The effects of colchicine and hydroxychloroquine on the cyclo-oxygenases COX-1 and COX-2. | Rheumatology international 20050601 |
Development and validation of a reversed-phase liquid chromatographic method for separation and simultaneous determination of COX-2 inhibitors in pharmaceuticals and its application to biological fluids. | Biomedical chromatography : BMC 20050601 |
Adipose differentiation-related protein: a gonadotropin- and prostaglandin-regulated protein in primate periovulatory follicles. | Biology of reproduction 20050601 |
A pharmacological study of celecoxib and gemcitabine in patients with advanced pancreatic cancer. | Cancer chemotherapy and pharmacology 20050601 |
A randomized, double-blind, study of rofecoxib in patients with mild cognitive impairment. | Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 20050601 |
Celecoxib-induced deep-vein thrombosis. | The Annals of pharmacotherapy 20050601 |
Celecoxib tolerability in patients with hypersensitivity (mainly cutaneous reactions) to nonsteroidal anti-inflammatory drugs. | International archives of allergy and immunology 20050601 |
Tumor-associated down-regulation of 15-lipoxygenase-1 is reversed by celecoxib in colorectal cancer. | Annals of surgery 20050601 |
Selective COX-2 inhibition is favorable to human early and late-stage osteoarthritic cartilage: a human in vitro study. | Osteoarthritis and cartilage 20050601 |
Rescuing COX-2 inhibitors from the waste bin. | Journal of the National Cancer Institute 20050601 |
Chemotherapy induces the expression of cyclooxygenase-2 in non-small cell lung cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050601 |
Prospects for disease modification in ankylosing spondylitis: do nonsteroidal antiinflammatory drugs do more than treat symptoms? | Arthritis and rheumatism 20050601 |
Nonsteroidal antiinflammatory drugs reduce radiographic progression in patients with ankylosing spondylitis: a randomized clinical trial. | Arthritis and rheumatism 20050601 |
Efficacy of rofecoxib, celecoxib, and acetaminophen in patients with osteoarthritis of the knee. A combined analysis of the VACT studies. | The Journal of rheumatology 20050601 |
Evaluation of cyclooxygenase-2 inhibition in an orthotopic murine model of lung cancer for dose-dependent effect. | The Journal of thoracic and cardiovascular surgery 20050601 |
Adverse drug reactions to nonsteroidal anti-inflammatory drugs, COX-2 inhibitors and paracetamol in a paediatric hospital. | British journal of clinical pharmacology 20050601 |
Celecoxib, a selective inhibitor of cyclooxygenase 2 for therapy of diffuse anterior scleritis. | American journal of ophthalmology 20050601 |
Perspectives on novel therapies for bronchial carcinoma. | Expert opinion on pharmacotherapy 20050601 |
Prediction of genotoxicity of chemical compounds by statistical learning methods. | Chemical research in toxicology 20050601 |
Drug insight: cyclo-oxygenase 2 inhibitors and cardiovascular risk--where are we now? | Nature clinical practice. Cardiovascular medicine 20050601 |
Devitrification of amorphous celecoxib. | AAPS PharmSciTech 20050601 |
Increased serum interleukin-1beta and interleukin-6 in elderly, chronic schizophrenic patients on stable antipsychotic medication. | Neuropsychiatric disease and treatment 20050601 |
Pfizer Australia is fined for misleading promotion of celecoxib. | BMJ (Clinical research ed.) 20050528 |
Systematic overview of warfarin and its drug and food interactions. | Archives of internal medicine 20050523 |
New restrictions on celecoxib (Celebrex) use and the withdrawal of valdecoxib (Bextra). | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050510 |
Risk of hospitalization for myocardial infarction among users of rofecoxib, celecoxib, and other NSAIDs: a population-based case-control study. | Archives of internal medicine 20050509 |
Physiological effects of indomethacin and celecobix: an S-transform laser Doppler flowmetry signal analysis. | Physics in medicine and biology 20050507 |
1,5-Diarylpyrrole-3-acetic acids and esters as novel classes of potent and highly selective cyclooxygenase-2 inhibitors. | Journal of medicinal chemistry 20050505 |
Chemoprevention of 4-NQO-induced oral carcinogenesis by co-administration of all-trans retinoic acid loaded microspheres and celecoxib. | Journal of controlled release : official journal of the Controlled Release Society 20050505 |
Inhibition of COX-2 by celecoxib enhances glucocorticoid receptor function. | Molecular psychiatry 20050501 |
The effect of analgesic agents on the healing rat medial collateral ligament. | The American journal of sports medicine 20050501 |
Anti-rheumatic drug use and risk of hospitalization for congestive heart failure in rheumatoid arthritis. | Rheumatology (Oxford, England) 20050501 |
Blood pressure in Native Americans switched from celecoxib to rofecoxib. | The Annals of pharmacotherapy 20050501 |
Safety of celecoxib in patients with adverse reactions to nimesulide. | Allergy 20050501 |
Vioxx, Celebrex, Bextra....do we have a new target for anti-inflammatory and antipyretic therapy? | American journal of physiology. Regulatory, integrative and comparative physiology 20050501 |
Docetaxel and cyclooxygenase-2 inhibition with celecoxib for advanced non-small cell lung cancer progressing after platinum-based chemotherapy: a multicenter phase II trial. | Lung cancer (Amsterdam, Netherlands) 20050501 |
Diverse compounds mimic Alzheimer disease-causing mutations by augmenting Abeta42 production. | Nature medicine 20050501 |
Effect of preoperative Cox-II-selective NSAIDs (coxibs) on postoperative outcomes: a systematic review of randomized studies. | Acta anaesthesiologica Scandinavica 20050501 |
Dimethyl-celecoxib (DMC), a derivative of celecoxib that lacks cyclooxygenase-2-inhibitory function, potently mimics the anti-tumor effects of celecoxib on Burkitt's lymphoma in vitro and in vivo. | Cancer biology & therapy 20050501 |
COX-2 inhibitors still eyed for cancer prevention. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050501 |
Feasibility of RNA collection for micro-array gene expression analysis in the treatment of cervical carcinoma: a scientific correlate of RTOG C-0128. | Gynecologic oncology 20050501 |
A phase I clinical trial of thoracic radiotherapy and concurrent celecoxib for patients with unfavorable performance status inoperable/unresectable non-small cell lung cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050501 |
Cyclooxygenase-1 is a potential target for prevention and treatment of ovarian epithelial cancer. | Cancer research 20050501 |
Supra-additive growth inhibition by a celecoxib analogue and carboxyamido-triazole is primarily mediated through apoptosis. | Cancer research 20050501 |
Re: Efficacy of celecoxib, a COX-2-specific inhibitor, and naproxen in the management of acute ankle sprain: results of a double-blind, randomized controlled trial. | Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine 20050501 |
Effects of indomethacin and celecoxib on renal function in athletes. | Medicine and science in sports and exercise 20050501 |
High dose nonsteroidal anti-inflammatory drugs compromise spinal fusion. | Canadian journal of anaesthesia = Journal canadien d'anesthesie 20050501 |
Nonsteroidal anti-inflammatory drugs and hepatic toxicity: a systematic review of randomized controlled trials in arthritis patients. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20050501 |
Celecoxib-induced nephrotoxicity in a renal transplant recipient. | Pharmacotherapy 20050501 |
Cyclooxygenase-2 inhibitor-associated minimal-change disease. | Clinical nephrology 20050501 |
COX-2 inhibitors and acute interstitial nephritis: case report and review of the literature. | Clinical nephrology 20050501 |
FOLFIRI regimen in advanced colorectal cancer: the experience of the Gruppo Oncologico dell'Italia Meridionale (GOIM). | Annals of oncology : official journal of the European Society for Medical Oncology 20050501 |
Translational studies on aromatase, cyclooxygenases, and enzyme inhibitors in breast cancer. | The Journal of steroid biochemistry and molecular biology 20050501 |
Celecoxib induces heme-oxygenase expression in glomerular mesangial cells. | Annals of the New York Academy of Sciences 20050501 |
COX-2 inhibitors and genetic background reduce mammary tumorigenesis in cyclooxygenase-2 transgenic mice. | Prostaglandins & other lipid mediators 20050501 |
DMC: novel celecoxib derivatives to rap cancer. | Cancer biology & therapy 20050501 |
Enhanced in vitro percutaneous absorption and in vivo anti-inflammatory effect of a selective cyclooxygenase inhibitor using microemulsion. | Drug development and industrial pharmacy 20050501 |
Clinical pharmacokinetic of celecoxib in healthy Thai volunteers. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20050501 |
What are the effects of cyclooxygenase-2-specific inhibitors on the small bowel? | Nature clinical practice. Gastroenterology & hepatology 20050501 |
Indomethacin-induced activation of the death receptor-mediated apoptosis pathway circumvents acquired doxorubicin resistance in SCLC cells. | British journal of cancer 20050425 |
Effect of celecoxib, a cyclooxygenase-2 inhibitor, on the pathophysiology of adjuvant arthritis in rat. | European journal of pharmacology 20050425 |
Researchers plan to continue to study COX-2 inhibitors in cancer treatment and prevention. | Journal of the National Cancer Institute 20050420 |
Synthesis and biological evaluation of 3,4-diphenyl-1,2,5-oxadiazole-2-oxides and 3,4-diphenyl-1,2,5-oxadiazoles as potential hybrid COX-2 inhibitor/nitric oxide donor agents. | Bioorganic & medicinal chemistry 20050415 |
Minimizing complications from nonsteroidal antiinflammatory drugs: cost-effectiveness of competing strategies in varying risk groups. | Arthritis and rheumatism 20050415 |
[Enhancing effects of celecoxib on the growth inhibition of pancreatic carcinoma by gemcitabine treatment]. | Zhonghua yi xue za zhi 20050413 |
Does the dose make the poison? | Science (New York, N.Y.) 20050408 |
[COX-2 inhibitors--one step forward and two steps back]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20050407 |
Celecoxib decreases endothelial tissue factor expression through inhibition of c-Jun terminal NH2 kinase phosphorylation. | Circulation 20050405 |
The risk for myocardial infarction with cyclooxygenase-2 inhibitors: a population study of elderly adults. | Annals of internal medicine 20050405 |
Clinical effects of COX-2 inhibitors on cognition in schizophrenia. | European archives of psychiatry and clinical neuroscience 20050401 |
Early vasodilator response to anodal current application in human is not impaired by cyclooxygenase-2 blockade. | American journal of physiology. Heart and circulatory physiology 20050401 |
Suppression of accelerated tumor growth in surgical wounds by celecoxib and indomethacin. | Head & neck 20050401 |
Preemptive analgesia by zaltoprofen that inhibits bradykinin action and cyclooxygenase in a post-operative pain model. | Neuroscience research 20050401 |
Design, synthesis, and biological evaluation of N-acetyl-2-carboxybenzenesulfonamides: a novel class of cyclooxygenase-2 (COX-2) inhibitors. | Bioorganic & medicinal chemistry 20050401 |
Factors associated with celecoxib and rofecoxib utilization. | The Annals of pharmacotherapy 20050401 |
Acute tocolysis. | Current opinion in obstetrics & gynecology 20050401 |
Development and pharmacological characterization of a rat model of osteoarthritis pain. | Pain 20050401 |
Design, synthesis, biological evaluation and molecular docking of curcumin analogues as antioxidant, cyclooxygenase inhibitory and anti-inflammatory agents. | Bioorganic & medicinal chemistry letters 20050401 |
Patient characteristics associated with outpatient prescriptions for nabumetone and oxaprozin versus celecoxib and rofecoxib. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20050401 |
Adoption of celecoxib and rofecoxib: a nationwide database study. | Journal of clinical pharmacy and therapeutics 20050401 |
Integrative role of cPLA with COX-2 and the effect of non-steriodal anti-inflammatory drugs in a transgenic mouse model of amyotrophic lateral sclerosis. | Journal of neurochemistry 20050401 |
Enhanced growth inhibition and apoptosis induction in NSCLC cell lines by combination of celecoxib and 4HPR at clinically relevant concentrations. | Cancer biology & therapy 20050401 |
Inhibition of cyclooxygenase 2 synthesis suppresses Herpes simplex virus type 1 reactivation. | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20050401 |
An unusual case of diarrhoea. | Australian family physician 20050401 |
Clinical pharmacology of lumiracoxib, a second-generation cyclooxygenase 2 selective inhibitor. | Expert opinion on investigational drugs 20050401 |
Efficacy and tolerability of lumiracoxib 100 mg once daily in knee osteoarthritis: a 13-week, randomized, double-blind study vs. placebo and celecoxib. | Current medical research and opinion 20050401 |
Raising the safety bar--the FDA's coxib meeting. | The New England journal of medicine 20050331 |
Post-training intrahippocampal infusion of the COX-2 inhibitor celecoxib impaired spatial memory retention in rats. | European journal of pharmacology 20050328 |
Subconjunctivally administered celecoxib-PLGA microparticles sustain retinal drug levels and alleviate diabetes-induced oxidative stress in a rat model. | European journal of pharmacology 20050328 |
[Ulcerating haemorrhagic colitis induced by celecoxib]. | Presse medicale (Paris, France : 1983) 20050326 |
Reassessment of the benefit/risk-ratio of selective COX-2-inhibitors. | Swiss medical weekly 20050319 |
Inhibitory avoidance memory retention in the elevated T-maze is impaired after perivascular manipulation of the common carotid arteries. | Life sciences 20050318 |
Cardiovascular risk associated with celecoxib in a clinical trial for colorectal adenoma prevention. | The New England journal of medicine 20050317 |
COX-2 inhibitors--lessons in drug safety. | The New England journal of medicine 20050317 |
COX-2 inhibitors--a lesson in unexpected problems. | The New England journal of medicine 20050317 |
A novel celecoxib derivative, OSU03012, induces cytotoxicity in primary CLL cells and transformed B-cell lymphoma cell line via a caspase- and Bcl-2-independent mechanism. | Blood 20050315 |
Meta-analysis of cyclooxygenase-2 inhibitors and their effects on blood pressure. | Archives of internal medicine 20050314 |
Valdecoxib: assessment of cyclooxygenase-2 potency and selectivity. | The Journal of pharmacology and experimental therapeutics 20050301 |
The effects of selective and nonselective cyclooxygenase inhibitors on endothelin-1-induced fever in rats. | American journal of physiology. Regulatory, integrative and comparative physiology 20050301 |
A COX-2 inhibitor prevents the esophageal inflammation-metaplasia-adenocarcinoma sequence in rats. | Carcinogenesis 20050301 |
The cyclooxygenase-2 inhibitor GW406381X [2-(4-ethoxyphenyl)-3-[4-(methylsulfonyl)phenyl]-pyrazolo[1,5-b]pyridazine] is effective in animal models of neuropathic pain and central sensitization. | The Journal of pharmacology and experimental therapeutics 20050301 |
Complexation of celecoxib with beta-cyclodextrin: characterization of the interaction in solution and in solid state. | Journal of pharmaceutical sciences 20050301 |
A combination of docosahexaenoic acid and celecoxib prevents prostate cancer cell growth in vitro and is associated with modulation of nuclear factor-kappaB, and steroid hormone receptors. | International journal of oncology 20050301 |
The restorative effect of a selective cyclooxygenase-2 inhibitor on urothelial cell-cell interactions after partial bladder outlet obstruction in rats. | BJU international 20050301 |
Effects of celecoxib and naproxen on renal function in nonazotemic patients with cirrhosis and ascites. | Hepatology (Baltimore, Md.) 20050301 |
Celecoxib improves the efficiency of the locomotor mechanism in patients with knee osteoarthritis. A randomised, placebo, double-blind and cross-over trial. | Osteoarthritis and cartilage 20050301 |
A placebo-controlled screening trial of celecoxib for the treatment of cocaine dependence. | Addiction (Abingdon, England) 20050301 |
Modulation of celecoxib pharmacokinetics by food in pediatric patients. | Clinical pharmacology and therapeutics 20050301 |
The effect of cyclooxygenase-2 inhibition on analgesia and spinal fusion. | The Journal of bone and joint surgery. American volume 20050301 |
Painful lessons. | Nature structural & molecular biology 20050301 |
The safety of the perioperative administration of cyclooxygenase-2 inhibitors for post-surgical pain. | Acta anaesthesiologica Scandinavica 20050301 |
Induction of claudin-4 by nonsteroidal anti-inflammatory drugs and its contribution to their chemopreventive effect. | Cancer research 20050301 |
Anaphylactic shock caused by a selective allergy to celecoxib, with no allergy to rofecoxib or sulfamethoxazole. | The Journal of allergy and clinical immunology 20050301 |
Celecoxib inhibits prostate cancer growth: evidence of a cyclooxygenase-2-independent mechanism. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050301 |
Overexpression of 5-lipoxygenase and cyclooxygenase 2 in hamster and human oral cancer and chemopreventive effects of zileuton and celecoxib. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050301 |
[Anti-angiogenic therapy for gastrointestinal tumours]. | Zeitschrift fur Gastroenterologie 20050301 |
Cyclooxygenase-2 inhibitors and cardiovascular risk. | The Canadian journal of cardiology 20050301 |
Uptake of new drugs in rural and urban areas of Queensland, Australia: the example of COX-2 inhibitors. | European journal of clinical pharmacology 20050301 |
A tale of two coxibs. | JAAPA : official journal of the American Academy of Physician Assistants 20050301 |
COX-2 inhibitors and cardiovascular toxicity: a class effect? | South Dakota journal of medicine 20050301 |
Molecular interactions in celecoxib-PVP-meglumine amorphous system. | The Journal of pharmacy and pharmacology 20050301 |
Formulation and evaluation of aerosolized celecoxib for the treatment of lung cancer. | Pharmaceutical research 20050301 |
Tolerability of selective cyclooxygenase inhibitor, celecoxib, in patients with analgesic intolerance. | The Journal of asthma : official journal of the Association for the Care of Asthma 20050301 |
Albumin microspheres as carriers for the antiarthritic drug celecoxib. | AAPS PharmSciTech 20050301 |
Lessons to learn from the COX-2 saga. Yes, FDA reforms are needed. And marketing distorts how medications are used. But one moral to the story is that all drugs have risks. | Harvard health letter 20050301 |
Coxibs: can this class of drugs survive? | Vascular health and risk management 20050301 |
Drug safety. FDA panel urges caution on many anti-inflammatory drugs. | Science (New York, N.Y.) 20050225 |
Vioxx may go back on sale after scraping past FDA panel. | Nature 20050224 |
Celecoxib derivatives induce apoptosis via the disruption of mitochondrial membrane potential and activation of caspase 9. | International journal of cancer 20050220 |
Sulindac and its metabolites inhibit invasion of glioblastoma cells via down-regulation of Akt/PKB and MMP-2. | Journal of cellular biochemistry 20050215 |
Carbonic anhydrase inhibitors. Inhibition of the membrane-bound human and bovine isozymes IV with sulfonamides. | Bioorganic & medicinal chemistry letters 20050215 |
Cytochrome P4502C9-derived epoxyeicosatrienoic acids induce the expression of cyclooxygenase-2 in endothelial cells. | Arteriosclerosis, thrombosis, and vascular biology 20050201 |
Coxib medications to be handled with care. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20050201 |
Are all COX-2 inhibitors created equal? | Hypertension (Dallas, Tex. : 1979) 20050201 |
In vivo endothelial interaction between ACE and COX inhibitors. | Prostaglandins, leukotrienes, and essential fatty acids 20050201 |
Selective COX-2 inhibitors and renal injury in salt-sensitive hypertension. | Hypertension (Dallas, Tex. : 1979) 20050201 |
Selective COX-2 inhibitor regulates the MAP kinase signaling pathway in human osteoarthritic chondrocytes after induction of nitric oxide. | International journal of molecular medicine 20050201 |
Central nervous system concentrations of cyclooxygenase-2 inhibitors in humans. | Anesthesiology 20050201 |
Summaries for patients. Cyclooxygenase-2 inhibitors and heart attacks: varying effects? | Annals of internal medicine 20050201 |
Patients exposed to rofecoxib and celecoxib have different odds of nonfatal myocardial infarction. | Annals of internal medicine 20050201 |
Celecoxib and ketoprofen for pain management during tonsillectomy: a placebo-controlled clinical trial. | Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 20050201 |
Video capsule endoscopy to prospectively assess small bowel injury with celecoxib, naproxen plus omeprazole, and placebo. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20050201 |
COX-2 inhibitors: cancer prevention or cardiovascular risk? | The Lancet. Oncology 20050201 |
COX-2 selective inhibitors--important lessons learned. | Lancet (London, England) 20050201 |
Risk of acute myocardial infarction and sudden cardiac death in patients treated with cyclo-oxygenase 2 selective and non-selective non-steroidal anti-inflammatory drugs: nested case-control study. | Lancet (London, England) 20050201 |
Reduction of opioid-related adverse events using opioid-sparing analgesia with COX-2 inhibitors lacks documentation: a systematic review. | Acta anaesthesiologica Scandinavica 20050201 |
Extracolonic manifestations of familial adenomatous polyposis after proctocolectomy. | Archives of surgery (Chicago, Ill. : 1960) 20050201 |
Colorectal cancer prevention: is an ounce of prevention worth a pound of cure? | Seminars in oncology 20050201 |
Targeting vascular endothelial growth factor and angiogenesis for the treatment of colorectal cancer. | Seminars in oncology 20050201 |
Cyclooxygenase-2 inhibition in colorectal cancer: boom or bust? | Seminars in oncology 20050201 |
Pfizer: Celebrex increases heart attack risk. | Health news (Waltham, Mass.) 20050201 |
Coxib toxicity: a likely class effect. | Prescrire international 20050201 |
[Prevention of heterotopic ossifications in hip arthroplasty: effectiveness of selective Cox-2 inhibitors (celecoxib) versus ketoprofen]. | Revue de chirurgie orthopedique et reparatrice de l'appareil moteur 20050201 |
Institutional review boards must conduct safety review. | Human research report 20050201 |
Safety of celecoxib in patients with adverse skin reactions to acetaminophen (paracetamol) and nimesulide associated or not with common non-steroidal anti-inflammatory drugs. | European annals of allergy and clinical immunology 20050201 |
Rofecoxib for osteoarthritis. | The Cochrane database of systematic reviews 20050125 |
The Effects of cyclooxygenase-2 inhibitors and nonsteroidal anti-inflammatory therapy on 24-hour blood pressure in patients with hypertension, osteoarthritis, and type 2 diabetes mellitus. | Archives of internal medicine 20050124 |
Risk of upper gastrointestinal hemorrhage in warfarin users treated with nonselective NSAIDs or COX-2 inhibitors. | Archives of internal medicine 20050124 |
Increased endothelial uptake of paclitaxel as a potential mechanism for its antiangiogenic effects: potentiation by Cox-2 inhibition. | International journal of cancer 20050120 |
Arthritis medicines and cardiovascular events--'house of coxibs'. | JAMA 20050119 |
A randomised phase II trial of docetaxel vs docetaxel and irinotecan in patients with stage IIIb-IV non-small-cell lung cancer who failed first-line treatment. | British journal of cancer 20050117 |
Design and synthesis of (E)-1,1,2-triarylethenes: novel inhibitors of the cyclooxygenase-2 (COX-2) isozyme. | Bioorganic & medicinal chemistry letters 20050117 |
NSAID alternatives. | The Medical letter on drugs and therapeutics 20050117 |
Phase II trial of irinotecan plus celecoxib in adults with recurrent malignant glioma. | Cancer 20050115 |
Targeting cyclooxygenase-2 reduces overt toxicity toward low-dose vinblastine and extends survival of juvenile mice with Friend disease. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050115 |
Celecoxib does not induce convulsions nor does it affect GABAA receptor binding activity in the presence of new quinolones in mice. | European journal of pharmacology 20050110 |
The effects of selective cyclooxygenase-2 inhibitors, celecoxib and rofecoxib, on experimental colitis induced by acetic acid in rats. | European journal of pharmacology 20050110 |
Different cell kinetic changes in rat stomach cancer after treatment with celecoxib or indomethacin: implications on chemoprevention. | World journal of gastroenterology 20050107 |
Dietary zinc modulation of COX-2 expression and lingual and esophageal carcinogenesis in rats. | Journal of the National Cancer Institute 20050105 |
R-130823, a novel inhibitor of p38 MAPK, ameliorates hyperalgesia and swelling in arthritis models. | European journal of pharmacology 20050104 |
Distinct cAMP signaling pathways differentially regulate alpha2C-adrenoceptor expression: role in serum induction in human arteriolar smooth muscle cells. | American journal of physiology. Heart and circulatory physiology 20050101 |
Treating osteoarthritis with cyclooxygenase-2-specific inhibitors: what are the benefits of avoiding blood pressure destabilization? | Hypertension (Dallas, Tex. : 1979) 20050101 |
Signaling via the angiotensin-converting enzyme enhances the expression of cyclooxygenase-2 in endothelial cells. | Hypertension (Dallas, Tex. : 1979) 20050101 |
Celecoxib, a selective cyclooxygenase-2 inhibitor, decreases monocyte chemoattractant protein-1 expression and neointimal hyperplasia in the rabbit atherosclerotic balloon injury model. | Journal of cardiovascular pharmacology 20050101 |
The prevention of post-surgical neuralgia. | Pain 20050101 |
The selective cyclooxygenase-2 inhibitor celecoxib modulates the formation of vasoconstrictor eicosanoids and activates PPARgamma. Influence of albumin. | Journal of hepatology 20050101 |
Cyclooxygenase-2 specific inhibitors and upper gastrointestinal tolerability in patients with osteoarthritis receiving concomitant low dose aspirin: pooled analysis of 2 trials. | The Journal of rheumatology 20050101 |
Survivin: a novel target for indomethacin-induced gastric injury. | Gastroenterology 20050101 |
Clinical consequences of cytochrome P450 2C9 polymorphisms. | Clinical pharmacology and therapeutics 20050101 |
Do early premalignant changes in normal breast epithelial cells predict cancer development? | Breast cancer research : BCR 20050101 |
Efficacy of lumiracoxib in osteoarthritis: a review of nine studies. | The Journal of international medical research 20050101 |
Nonsteroidal antiinflammatory drugs differentially suppress endometriosis in a murine model. | Fertility and sterility 20050101 |
Celecoxib inhibits ureteral contractility and prostanoid release. | Urology 20050101 |
Effect of maternal administration of selective cyclooxygenase (COX)-2 inhibitors on renal size, growth factors, proteinases, and COX-2 secretion in the fetal rabbit. | Biology of the neonate 20050101 |
[Vision impairment by COX-2 inhibitor and the sequelae of voluntary Vioxx recall]. | Klinische Monatsblatter fur Augenheilkunde 20050101 |
Taking stock of coxibs. | Drug and therapeutics bulletin 20050101 |
Effect of specific and non-specific inhibition of COX-2 on renal oxygenation before and after water diuresis. | Nephron. Physiology 20050101 |
Phase I/II study of selective cyclooxygenase-2 inhibitor celecoxib as a radiation sensitizer in patients with unresectable brain metastases. | Journal of neuro-oncology 20050101 |
Long-term follow-up of a randomized clinical trial assessing the efficacy of medication, acupuncture, and spinal manipulation for chronic mechanical spinal pain syndromes. | Journal of manipulative and physiological therapeutics 20050101 |
Do selective cyclo-oxygenase-2 inhibitors have a future? | Drug safety 20050101 |
Prescription channeling of COX-2 inhibitors and traditional nonselective nonsteroidal anti-inflammatory drugs: a population-based case-control study. | Arthritis research & therapy 20050101 |
Clinical trial update: National Cancer Institute of Canada. | Breast cancer research : BCR 20050101 |
JTE-522, a selective COX-2 inhibitor, inhibits growth of pulmonary metastases of colorectal cancer in rats. | BMC cancer 20050101 |
Drug fiasco highlights need for more openness. | British journal of community nursing 20050101 |
Effect of nonsteroidal anti-inflammatory drugs with varying extent of COX-2-COX-1 selectivity on urinary sodium and potassium excretion in the rat. | Canadian journal of physiology and pharmacology 20050101 |
Efficacy and tolerability of lumiracoxib in the treatment of osteoarthritis of the knee: a 13-week, randomized, double-blind comparison with celecoxib and placebo. | Clinical therapeutics 20050101 |
Celecoxib-cyclodextrin systems: characterization and evaluation of in vitro and in vivo advantage. | Drug development and industrial pharmacy 20050101 |
[Tubulointerstitial nephritis associated with treatment with selective Cox-2 inhibitors, celecoxib and rofecoxib]. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20050101 |
[Nephrotic syndrome associated to celecoxib]. | Nefrologia : publicacion oficial de la Sociedad Espanola Nefrologia 20050101 |
A phase I study of 5-fluorouracil, leucovorin, and celecoxib in patients with incurable colorectal cancer. | Prostaglandins & other lipid mediators 20050101 |
The effects of Celecoxib on inflammation and synovial microcirculation in murine antigen-induced arthritis. | Clinical and experimental rheumatology 20050101 |
Cyclo-oxygenase-2 inhibitors: when should they be used in the elderly? | Drugs & aging 20050101 |
Growth inhibitory effect of celecoxib and rofecoxib on human colorectal carcinoma cell lines. | Anticancer research 20050101 |
Individual and combined effects of selective cyclooxygenase-2 inhibitor and omega-3 fatty acid on endotoxin-induced periodontitis in rats. | Journal of periodontology 20050101 |
Incidence of thrombotic cardiovascular events in patients taking celecoxib compared with those taking rofecoxib: interim results from the New Zealand Intensive Medicines Monitoring Programme. | Drug safety 20050101 |
Celecoxib was noninferior to diclofenac plus omeprazole for preventing gastroduodenal ulcer recurrence in high-risk patients with arthritis. | ACP journal club 20050101 |
Assessing the cost-effectiveness of COX-2 specific inhibitors for arthritis in the Veterans Health Administration. | Current medical research and opinion 20050101 |
The effects of non-steroidal anti-inflammatory drugs (selective and non-selective) on the treatment of periodontal diseases. | Current pharmaceutical design 20050101 |
Suppression of colitis-related mouse colon carcinogenesis by a COX-2 inhibitor and PPAR ligands. | BMC cancer 20050101 |
Tolerability and adverse events in clinical trials of celecoxib in osteoarthritis and rheumatoid arthritis: systematic review and meta-analysis of information from company clinical trial reports. | Arthritis research & therapy 20050101 |
Can chronic use of anti-inflammatory agents paradoxically promote chronic inflammation through compensatory host response? | Medical hypotheses 20050101 |
Study on the inclusion complex between beta-cyclodextrin and celecoxib by spectrofluorimetry and its analytical application. | Farmaco (Societa chimica italiana : 1989) 20050101 |
Spray drying for generation of a ternary amorphous system of celecoxib, PVP, and meglumine. | Pharmaceutical development and technology 20050101 |
[Celecoxib prescription: data from the 'Sécurité Sociale' database of the Aquitaine Region, South-Western, France]. | Therapie 20050101 |
Celecoxib inhibits proliferation and induces apoptosis via cyclooxygenase-2 pathway in human pancreatic carcinoma cells. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20050101 |
In vivo effect of celecoxib and tenoxicam on oxidant/ anti-oxidant status of patients with knee osteoarthritis. | Annals of clinical and laboratory science 20050101 |
SuperLigands - a database of ligand structures derived from the Protein Data Bank. | BMC bioinformatics 20050101 |
Relative thromboembolic risks associated with COX-2 inhibitors. | The Annals of pharmacotherapy 20050101 |
Effect of LLLT Ga-Al-As (685 nm) on LPS-induced inflammation of the airway and lung in the rat. | Lasers in medical science 20050101 |
COX-2 selective inhibitors in the treatment of arthritis: a rheumatologist perspective. | Current topics in medicinal chemistry 20050101 |
Impact of COX-2 inhibitors in common clinical practice a gastroenterologist's perspective. | Current topics in medicinal chemistry 20050101 |
Selective COX-2 inhibitors and risk of myocardial infarction. | Journal of vascular research 20050101 |
Tetrandrine and thapsigargin release arachidonic acid from cells in culture and stimulate prostacyclin production in rat liver cells, but may do so by different pathways. | BMC pharmacology 20050101 |
Mechanisms underlying the growth inhibitory effects of the cyclo-oxygenase-2 inhibitor celecoxib in human breast cancer cells. | Breast cancer research : BCR 20050101 |
[Gastroduodenal safety of selective inhibitors of cyclooxigenase-2: practical validation]. | Terapevticheskii arkhiv 20050101 |
Celecoxib increased cardiovascular events in patients with colorectal adenomas. | ACP journal club 20050101 |
[Role of prostaglandins in the pathogenesis of stomach ulcer and gastropathy caused by non-steroid anti-inflammatory drugs]. | Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20050101 |
Quantification and characterisation of cyclo-oxygenase and lipid peroxidation inhibitory anthocyanins in fruits of Amelanchier. | Phytochemical analysis : PCA 20050101 |
Utilization of non-steroidal anti-inflammatory drugs in Quebec: adherence to the Canadian consensus on prescription guidelines. | The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique 20050101 |
Prevention of tumors of the large intestine by celecoxib in mice. | In vivo (Athens, Greece) 20050101 |
Anti-inflammatory effects of specific cyclooxygenase 2,5-lipoxygenase, and inducible nitric oxide synthase inhibitors on experimental autoimmune anterior uveitis (EAAU). | Ocular immunology and inflammation 20050101 |
New agents in intravesical chemotherapy of superficial bladder cancer. | Scandinavian journal of urology and nephrology 20050101 |
Analgesic effects of nonsteroidal antiinflammatory drugs, acetaminophen, and morphine in a mouse model of bone cancer pain. | Journal of anesthesia 20050101 |
Usefulness of montelukast to prevent adverse reactions to COX-2 selective inhibitors: a case report. | Journal of investigational allergology & clinical immunology 20050101 |
Regulatory paternalism in the market for drugs: lessons from Vioxx and Celebrex. | Yale journal of health policy, law, and ethics 20050101 |
The combination of the selective cyclooxygenase-2 inhibitor celecoxib with weekly paclitaxel is a safe and active second-line therapy for non-small cell lung cancer: a phase II study with biological correlates. | Cancer journal (Sudbury, Mass.) 20050101 |
Pharmacological profile of celecoxib, a specific cyclooxygenase-2 inhibitor. | Arzneimittel-Forschung 20050101 |
Pancreatic stellate cells (PSCs) express cyclooxygenase-2 (COX-2) and pancreatic cancer stimulates COX-2 in PSCs. | Molecular cancer 20050101 |
Treatment of osteoarthritis of the knee with a topical diclofenac solution: a randomised controlled, 6-week trial [ISRCTN53366886]. | BMC musculoskeletal disorders 20050101 |
A phase II trial of irinotecan, 5-fluorouracil and leucovorin combined with celecoxib and glutamine as first-line therapy for advanced colorectal cancer. | Oncology 20050101 |
Inhibitory effects of Celecoxib and Sc-58125 on proliferation of human carcinoma of larynx Hep-2 in vitro. | Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 20050101 |
A comparison of reported gastrointestinal and thromboembolic events between rofecoxib and celecoxib using observational data. | Drug safety 20050101 |
FDA announces changes affecting the marketing of non-steroidal anti-inflammatory drugs. | FDA consumer 20050101 |
Potential protective effects of NSAIDs/ASA in oxidatively stressed human lens epithelial cells and intact mouse lenses in culture. | Ophthalmic research 20050101 |
[Relapsing polychondritis. A case report of a patient treated with methotrexate and celecoxib]. | Revista medica del Instituto Mexicano del Seguro Social 20050101 |
Establishment and characterization of a pancreatic carcinoma cell line derived from malignant pleural effusion. | Oncology 20050101 |
The effect of conflict of interest on biomedical research and clinical practice guidelines: can we trust the evidence in evidence-based medicine? | The Journal of the American Board of Family Practice 20050101 |
Survey of oxaliplatin-associated neurotoxicity using an interview-based questionnaire in patients with metastatic colorectal cancer. | BMC cancer 20050101 |
Current state of therapy for pain and inflammation. | Arthritis research & therapy 20050101 |
Cardiovascular and gastrointestinal effects of COX-2 inhibitors and NSAIDs: achieving a balance. | Arthritis research & therapy 20050101 |
Practical approaches to minimizing gastrointestinal and cardiovascular safety concerns with COX-2 inhibitors and NSAIDs. | Arthritis research & therapy 20050101 |
Balancing the gastrointestinal benefits and risks of nonselective NSAIDs. | Arthritis research & therapy 20050101 |
Celecoxib analogues disrupt Akt signaling, which is commonly activated in primary breast tumours. | Breast cancer research : BCR 20050101 |
The Fourth International Symposium on the Intraductal Approach to Breast Cancer, Santa Barbara, California, 10-13 March 2005. | Breast cancer research : BCR 20050101 |
Treating breast cancer through novel inhibitors of the phosphatidylinositol 3'-kinase pathway. | Breast cancer research : BCR 20050101 |
Comparison of reporting of Stevens-Johnson syndrome and toxic epidermal necrolysis in association with selective COX-2 inhibitors. | Drug safety 20050101 |
COX-2 inhibitors as adjunctive therapy in schizophrenia: rationale for use and evidence to date. | CNS drugs 20050101 |
[Sex-related differences in the antinociceptive effect of some non-narcotic analgetics in rats: the role of biotransformation]. | Eksperimental'naia i klinicheskaia farmakologiia 20050101 |
Role of molecular interaction in stability of celecoxib-PVP amorphous systems. | Molecular pharmaceutics 20050101 |
Influence of Helicobacter pylori and omeprazole on celecoxib-induced gastroduodenal mucosal injury. | Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology 20050101 |
Early relief of osteoarthritis symptoms with a natural mineral supplement and a herbomineral combination: a randomized controlled trial [ISRCTN38432711]. | Journal of inflammation (London, England) 20050101 |
Cardiovascular complications of non-steroidal anti-inflammatory drugs. | Annals of clinical and laboratory science 20050101 |
Prostanoids as friends, not foes: further evidence from the interference by cycloxygenase-inhibitory drugs when inducing tolerance to experimental arthritigens in rats. | Inflammopharmacology 20050101 |
Single subject pharmacological-MRI (phMRI) study: modulation of brain activity of psoriatic arthritis pain by cyclooxygenase-2 inhibitor. | Molecular pain 20050101 |
TOIB Study. Are topical or oral ibuprofen equally effective for the treatment of chronic knee pain presenting in primary care: a randomised controlled trial with patient preference study. [ISRCTN79353052]. | BMC musculoskeletal disorders 20050101 |
The efficacy and toleration of celecoxib (Celebrex) in the treatment of osteoarthritis in Nigeria: a multicentre study. | West African journal of medicine 20050101 |
Comparative study of anti-inflammatory and ulcerogenic activities of different cyclo-oxygenase inhibitors. | Inflammopharmacology 20050101 |
[Cyclooxygenase-2 inhibitors and the ethics of research]. | Medicina 20050101 |
A comparison between the effects of acetaminophen and celecoxib on bone fracture healing in rats. | Journal of orthopaedic trauma 20050101 |
Long-term use of non-steroidal anti-inflammatory drugs and the risk of myocardial infarction in the general population. | BMC medicine 20050101 |
Etoricoxib in the treatment of osteoarthritis over 52-weeks: a double-blind, active-comparator controlled trial [NCT00242489]. | BMC musculoskeletal disorders 20050101 |
The use of celecoxib for reduction of pain after subpectoral breast augmentation. | Aesthetic plastic surgery 20050101 |
Association between frequent use of nonsteroidal anti-inflammatory drugs and breast cancer. | BMC cancer 20050101 |
Introduction - The coxib controversies. | Inflammopharmacology 20050101 |
The use of NSAIDs in rheumatic disorders 2005: a global perspective. | Inflammopharmacology 20050101 |
COX-2 inhibitors: a story of greed, deception and death. | Inflammopharmacology 20050101 |
Mechanisms involved in the anti-inflammatory effect of a standardized willow bark extract. | Arzneimittel-Forschung 20050101 |
Effect of celecoxib on Ca2+ fluxes and proliferation in MDCK renal tubular cells. | Journal of receptor and signal transduction research 20050101 |
Gastrointestinal safety of amtolmetin guacyl in comparison with celecoxib in patients with rheumatoid arthritis. | Clinical and experimental rheumatology 20050101 |
The future of traditional nonsteroidal antiinflammatory drugs and cyclooxygenase-2 inhibitors in the treatment of inflammation and pain. | Pharmacological reports : PR 20050101 |
Safety of celecoxib in patients with adverse skin reactions to acetaminophen (paracetamol) and other non-steroidal anti-inflammatory drugs. | Journal of investigational allergology & clinical immunology 20050101 |
[Docetaxel and novel strategies in the treatment of NSCLC]. | Tumori 20050101 |
Modeling of drug release from celecoxib-PVP-meglumine amorphous systems. | PDA journal of pharmaceutical science and technology 20050101 |
[Untoward interactions between antihypertensives and nonsteroidal anti-inflammatory drugs]. | Lijecnicki vjesnik 20050101 |
Varied response of spontaneous tumors to antiangiogenic agents. | Advances in experimental medicine and biology 20050101 |
[Nonsteroidal antirheumatics and the kidney]. | Reumatizam 20050101 |
The risks and benefits of cyclo-oxygenase-2 inhibitors in prostate cancer: a review. | International journal of surgery (London, England) 20050101 |
Effect of celecoxib, a cyclooxygenase-2-specific inhibitor, on insulin sensitivity, C-reactive protein, homocysteine, and metabolic profile in overweight or obese subjects. | Metabolic syndrome and related disorders 20050101 |
COX-2 selective inhibitors and heart health. | Postgraduate medicine 20050101 |
Design, synthesis, and pharmacological evaluation of pyridinic analogues of nimesulide as cyclooxygenase-2 selective inhibitors. | Journal of medicinal chemistry 20041230 |
Rofecoxib, Merck, and the FDA. | The New England journal of medicine 20041230 |
Clinical trials. Halt of Celebrex study threatens drug's future, other trials. | Science (New York, N.Y.) 20041224 |
Carbonic anhydrase inhibitors. Inhibition of the prokariotic beta and gamma-class enzymes from Archaea with sulfonamides. | Bioorganic & medicinal chemistry letters 20041220 |
3-(2-Methoxytetrahydrofuran-2-yl)pyrazoles: a novel class of potent, selective cyclooxygenase-2 (COX-2) inhibitors. | Bioorganic & medicinal chemistry letters 20041220 |
Role of cyclooxygenase-2 in cytokine-induced beta-cell dysfunction and damage by isolated rat and human islets. | The Journal of biological chemistry 20041217 |
[Criteria for administration of Lantus, Levemir and Lyrica. Guidelines for administration of Celebra and Arcoxia]. | Ugeskrift for laeger 20041213 |
Nonsteroidal anti-inflammatory agents differ in their ability to suppress NF-kappaB activation, inhibition of expression of cyclooxygenase-2 and cyclin D1, and abrogation of tumor cell proliferation. | Oncogene 20041209 |
Clinical trials. Nail-biting time for trials of COX-2 drugs. | Science (New York, N.Y.) 20041203 |
New COX-2/5-LOX inhibitors: apoptosis-inducing agents potentially useful in prostate cancer chemotherapy. | Journal of medicinal chemistry 20041202 |
ABT-963 [2-(3,4-difluoro-phenyl)-4-(3-hydroxy-3-methyl-butoxy)-5-(4-methanesulfonyl-phenyl)-2H-pyridazin-3-one], a highly potent and selective disubstituted pyridazinone cyclooxgenase-2 inhibitor. | The Journal of pharmacology and experimental therapeutics 20041201 |
Nitric oxide (NO)-releasing naproxen (HCT-3012 [(S)-6-methoxy-alpha-methyl-2-naphthaleneacetic Acid 4-(nitrooxy)butyl ester]) interactions with aspirin in gastric mucosa of arthritic rats reveal a role for aspirin-triggered lipoxin, prostaglandins, and NO in gastric protection. | The Journal of pharmacology and experimental therapeutics 20041201 |
Up-regulation of cyclooxygenase-2 expression is involved in R(+)-methanandamide-induced apoptotic death of human neuroglioma cells. | Molecular pharmacology 20041201 |
Celecoxib inhibits angiogenesis by inducing endothelial cell apoptosis in human pancreatic tumor xenografts. | Cancer biology & therapy 20041201 |
Pharmacotherapy for diabetic retinopathy. | Current opinion in ophthalmology 20041201 |
Sulfone COX-2 inhibitors increase susceptibility of human LDL and plasma to oxidative modification: comparison to sulfonamide COX-2 inhibitors and NSAIDs. | Atherosclerosis 20041201 |
Current approaches to prevent NSAID-induced gastropathy--COX selectivity and beyond. | British journal of clinical pharmacology 20041201 |
Vioxx withdrawal alarms cancer prevention researchers. | Journal of the National Cancer Institute 20041201 |
Death receptor regulation and celecoxib-induced apoptosis in human lung cancer cells. | Journal of the National Cancer Institute 20041201 |
Formulation design of self-microemulsifying drug delivery systems for improved oral bioavailability of celecoxib. | Biological & pharmaceutical bulletin 20041201 |
Novel insights and therapeutical applications in the field of inhibitors of COX-2. | Current medicinal chemistry 20041201 |
Cutaneous vasculitis induced by cyclo-oxygenase-2 selective inhibitors. | Journal of the American Academy of Dermatology 20041201 |
Effect of cyclooxygenase-2 inhibitors on gastric emptying and small intestinal transit in humans. | Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20041201 |
[Inhibitory effects of celecoxib combined with octreotide on growth of multidrug resistant human gastric cancer cell line SGC7901/ADR]. | Ai zheng = Aizheng = Chinese journal of cancer 20041201 |
[A case report of disseminated malignant mesothelioma of peritoneum responding remarkably to thalidomide, celecoxib, vinorelbine and CDDP]. | Gan to kagaku ryoho. Cancer & chemotherapy 20041201 |
Growth inhibitory effects of celecoxib in human umbilical vein endothelial cells are mediated through G1 arrest via multiple signaling mechanisms. | Molecular cancer therapeutics 20041201 |
Celecoxib and radiation therapy in non-small-cell lung cancer. | Oncology (Williston Park, N.Y.) 20041201 |
Cisplatin, fluorouracil, celecoxib, and RT in resectable esophageal cancer: preliminary results. | Oncology (Williston Park, N.Y.) 20041201 |
Gemcitabine/Irinotecan/celecoxib in pancreatic cancer. | Oncology (Williston Park, N.Y.) 20041201 |
A painkiller is pulled from the market. So what do you do now? | Heart advisor 20041201 |
The influence of celecoxib on muscle fatigue resistance and mobility in elderly patients with inflammation. | The American journal of geriatric pharmacotherapy 20041201 |
Transparency in drug regulation: mirage or oasis? | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20041123 |
A new class of acyclic 2-alkyl-1,1,2-triaryl (Z)-olefins as selective cyclooxygenase-2 inhibitors. | Journal of medicinal chemistry 20041118 |
Quantification of the major urinary metabolite of PGE2 by a liquid chromatographic/mass spectrometric assay: determination of cyclooxygenase-specific PGE2 synthesis in healthy humans and those with lung cancer. | Analytical biochemistry 20041115 |
Design and synthesis of acyclic triaryl (Z)-olefins: a novel class of cyclooxygenase-2 (COX-2) inhibitors. | Bioorganic & medicinal chemistry 20041115 |
Regression of mouse prostatic intraepithelial neoplasia by nonsteroidal anti-inflammatory drugs in the transgenic adenocarcinoma mouse prostate model. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041115 |
Lumiracoxib is effective in the treatment of osteoarthritis of the knee: a 13 week, randomised, double blind study versus placebo and celecoxib. | Annals of the rheumatic diseases 20041101 |
Identification of 2,3-diaryl-pyrazolo[1,5-b]pyridazines as potent and selective cyclooxygenase-2 inhibitors. | Bioorganic & medicinal chemistry letters 20041101 |
The potential role of cyclooxygenase-2 inhibitors in the treatment of experimentally-induced mammary tumour: does celecoxib enhance the anti-tumour activity of doxorubicin? | Pharmacological research 20041101 |
Resveratrol analogues as selective cyclooxygenase-2 inhibitors: synthesis and structure-activity relationship. | Bioorganic & medicinal chemistry 20041101 |
Transfer of celecoxib into human milk. | Journal of human lactation : official journal of International Lactation Consultant Association 20041101 |
Increased expression of cyclooxygenase (COX)-2 in DMBA-induced hamster cheek pouch carcinogenesis and chemopreventive effect of a selective COX-2 inhibitor celecoxib. | Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20041101 |
Heterotropic modulation of sulfotransferase 2A1 activity by celecoxib: product ratio switching of ethynylestradiol sulfation. | Drug metabolism and disposition: the biological fate of chemicals 20041101 |
The potential role of non-steroidal anti-inflammatory drugs in treating Alzheimer's disease. | Expert opinion on investigational drugs 20041101 |
Disturbance of vision by COX-2 inhibitors. | Expert opinion on drug safety 20041101 |
Upper gastrointestinal adverse drug reactions and cyclo-oxygenase-2 inhibitors (celecoxib and rofecoxib): a case/non-case study from the French Pharmacovigilance Database. | European journal of clinical pharmacology 20041101 |
Risks of clinically significant upper gastrointestinal events with etodolac and naproxen: a historical cohort analysis. | Gastroenterology 20041101 |
Up-regulation of the enzymes involved in prostacyclin synthesis via Ras induces vascular endothelial growth factor. | Gastroenterology 20041101 |
Lack of effect of celecoxib on prostaglandin E2 concentrations in nipple aspirate fluid from women at increased risk of breast cancer. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20041101 |
Cyclooxygenase-2-dependent and -independent effects of celecoxib in pancreatic cancer cell lines. | Molecular cancer therapeutics 20041101 |
Psychotropic effects of COX-2 inhibitors--a possible new approach for the treatment of psychiatric disorders. | Pharmacopsychiatry 20041101 |
Pain management in osteoarthritis: a focus on onset of efficacy--a comparison of rofecoxib, celecoxib, acetaminophen, and nabumetone across four clinical trials. | The journal of pain : official journal of the American Pain Society 20041101 |
Cyclooxygenase-2 inhibitor induces apoptosis in breast cancer cells in an in vivo model of spontaneous metastatic breast cancer. | Molecular cancer research : MCR 20041101 |
Effect of processing on Celecoxib and its solvates. | Pharmaceutical development and technology 20041101 |
[Is there a future for COX-2 inhibitors?]. | Harefuah 20041101 |
[Role of prostaglandin E2 in regulation of urine excretion in saluresis, water and osmotic diuresis in rat]. | Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova 20041101 |
Docking studies on NSAID/COX-2 isozyme complexes using contact statistics analysis. | Journal of computer-aided molecular design 20041101 |
Protein kinase CbetaII regulates its own expression in rat intestinal epithelial cells and the colonic epithelium in vivo. | The Journal of biological chemistry 20041029 |
Prevention by celecoxib of secondary hyperalgesia induced by formalin in rats. | Life sciences 20041022 |
Coxibs and cardiovascular disease. | The New England journal of medicine 20041021 |
Multiple comparisons with a control in families with both one-sided and two-sided hypotheses. | Statistics in medicine 20041015 |
Cyclooxygenase-2 is expressed in neuroblastoma, and nonsteroidal anti-inflammatory drugs induce apoptosis and inhibit tumor growth in vivo. | Cancer research 20041015 |
Apoptosis protease activator protein-1 expression is dispensable for response of human melanoma cells to distinct proapoptotic agents. | Cancer research 20041015 |
Modulation of pulmonary leukotriene B4 production by cyclooxygenase-2 inhibitors and lipopolysaccharide. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041015 |
Apc deficiency is associated with increased Egfr activity in the intestinal enterocytes and adenomas of C57BL/6J-Min/+ mice. | The Journal of biological chemistry 20041008 |
Despite positive studies, popularity of chemoprevention drugs increasing slowly. | Journal of the National Cancer Institute 20041006 |
A new class of acyclic 2-alkyl-1,2-diaryl (E)-olefins as selective cyclooxygenase-2 (COX-2) inhibitors. | Bioorganic & medicinal chemistry letters 20041004 |
Modulation by celecoxib and difluoromethylornithine of the methylation of DNA and the estrogen receptor-alpha gene in rat colon tumors. | Carcinogenesis 20041001 |
Celecoxib-induced methemoglobinemia. | The Annals of pharmacotherapy 20041001 |
Aggravation of inflammatory bowel disease by cyclooxygenase-2 inhibitors in rats. | Pharmacology 20041001 |
HPLC method for determination of DRF-4367 in rat plasma: validation and its application to pharmacokinetics in Wistar rats. | Biomedical chromatography : BMC 20041001 |
Reduced sulfur mustard-induced skin toxicity in cyclooxygenase-2 knockout and celecoxib-treated mice. | Toxicology and applied pharmacology 20041001 |
Cancer-related anorexia/cachexia syndrome and oxidative stress: an innovative approach beyond current treatment. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20041001 |
Overexpression of 5-lipoxygenase in rat and human esophageal adenocarcinoma and inhibitory effects of zileuton and celecoxib on carcinogenesis. | Clinical cancer research : an official journal of the American Association for Cancer Research 20041001 |
Effect of chronic intake of NSAIDs and cyclooxygenase 2-selective inhibitors on esophageal cancer incidence. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20041001 |
Characterization of pristane-induced arthritis, a murine model of chronic disease: response to antirheumatic agents, expression of joint cytokines, and immunopathology. | Arthritis and rheumatism 20041001 |
Suppression of Peutz-Jeghers polyposis by inhibition of cyclooxygenase-2. | Gastroenterology 20041001 |
Celecoxib versus diclofenac plus omeprazole in high-risk arthritis patients: results of a randomized double-blind trial. | Gastroenterology 20041001 |
COX-2-specific inhibitor or proton pump inhibitor plus traditional NSAID: is either approach sufficient for patients at highest risk of NSAID-induced ulcers? | Gastroenterology 20041001 |
Interactions between aspirin and COX-2 inhibitors or NSAIDs in a rat thrombosis model. | Fundamental & clinical pharmacology 20041001 |
Celecoxib: a novel treatment for lung cancer. | Expert review of anticancer therapy 20041001 |
COX-2 inhibitors and risk of heart failure. | Lancet (London, England) 20041001 |
Safety of the new selective cyclooxygenase type 2 inhibitors rofecoxib and celecoxib in patients with anaphylactoid reactions to nonsteroidal anti-inflammatory drugs. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20041001 |
Stability and solubility of celecoxib-PVP amorphous dispersions: a molecular perspective. | Pharmaceutical research 20041001 |
Retinal delivery of celecoxib is several-fold higher following subconjunctival administration compared to systemic administration. | Pharmaceutical research 20041001 |
[Withdrawal of rofecoxib (Vioxx): what about cardiovascular safety of COX-2 selective non-steroidal anti-inflammatory drugs?]. | Revue medicale de Liege 20041001 |
The cyclooxygenase-2 inhibitor celecoxib is a potent inhibitor of human carbonic anhydrase II. | Inflammation 20041001 |
Effects of the celecoxib on the acute necrotizing pancreatitis in rats. | Inflammation 20041001 |
[Effect of celecoxib on enhancing the chemotherapic sensitivity of hydroxyurea to K562 cells and its mechanism]. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20041001 |
Delayed exercise-induced protection against arrhythmias in dogs--effect of celecoxib. | European journal of pharmacology 20040919 |
Involvement of spinal neurokinins, excitatory amino acids, proinflammatory cytokines, nitric oxide and prostanoids in pain facilitation induced by Phoneutria nigriventer spider venom. | Brain research 20040917 |
Signal transduction pathways regulating cyclooxygenase-2 expression: potential molecular targets for chemoprevention. | Biochemical pharmacology 20040915 |
Cyclooxygenase-2 modulates the insulin-like growth factor axis in non-small-cell lung cancer. | Cancer research 20040915 |
Risk assessment of NSAID-induced gastrointestinal toxicity in ambulatory care patients. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040915 |
RNA profiling of cyclooxygenases 1 and 2 in colorectal cancer. | British journal of cancer 20040913 |
Inhibition of cyclooxygenase-2, but not cyclooxygenase-1, reduces prostaglandin E2 secretion from diabetic rat retinas. | European journal of pharmacology 20040913 |
Aspirin-triggered, cyclooxygenase-2-dependent lipoxin synthesis modulates vascular tone. | Circulation 20040907 |
2-hydroxymethyl-4-[5-(4-methoxyphenyl)-3-trifluoromethyl-1H-1-pyrazolyl]-1-benzenesulfonamide (DRF-4367): an orally active COX-2 inhibitor identified through pharmacophoric modulation. | Organic & biomolecular chemistry 20040907 |
Endoplasmic reticulum stress response is involved in nonsteroidal anti-inflammatory drug-induced apoptosis. | Cell death and differentiation 20040901 |
[Treatment of osteoarthritis of the knee joint. Efficacy and tolerance to acemetacin slow release in comparison to celecoxib]. | Der Orthopade 20040901 |
Celecoxib induces apoptosis in cervical cancer cells independent of cyclooxygenase using NF-kappaB as a possible target. | Journal of cancer research and clinical oncology 20040901 |
Effect of anti-inflammatory drugs on pleurisy induced by latex of Calotropis procera in rats. | Pharmacological research 20040901 |
Eicosanoid metabolism in squamous cell carcinoma cell lines derived from primary and metastatic head and neck cancer and its modulation by celecoxib. | Cancer biology & therapy 20040901 |
Safety profile of celecoxib as used in general practice in England: results of a prescription-event monitoring study. | European journal of clinical pharmacology 20040901 |
A combination of selective COX-2 inhibitors and hydrogen peroxide increase the reactive oxygen species formation in osteosarcoma cells after X-ray irradiation. | International journal of molecular medicine 20040901 |
Chemoprevention of colorectal cancer. | Cancer chemotherapy and pharmacology 20040901 |
The effect of celecoxib on intrathecal morphine-induced pruritus in patients undergoing Caesarean section. | Anaesthesia 20040901 |
Molecular targeting therapy for pancreatic cancer. | Cancer chemotherapy and pharmacology 20040901 |
Efficacy of chitosan microspheres for controlled intra-articular delivery of celecoxib in inflamed joints. | The Journal of pharmacy and pharmacology 20040901 |
Treatment of painful temporomandibular joints with a cyclooxygenase-2 inhibitor: a randomized placebo-controlled comparison of celecoxib to naproxen. | Pain 20040901 |
Snake venom components enhance pain upon subcutaneous injection: an initial examination of spinal cord mediators. | Pain 20040901 |
Cost-effectiveness of treatment strategies for osteoarthritis of the knee in Taiwan. | The Journal of rheumatology 20040901 |
Gastroduodenal safety and tolerability of lumiracoxib compared with Ibuprofen and celecoxib in patients with osteoarthritis. | The Journal of rheumatology 20040901 |
1-[4-(Methylsulfonyl)phenyl]-5-phenyl-1H-pyrazole derivatives. | Acta crystallographica. Section C, Crystal structure communications 20040901 |
Prevention of colorectal cancer using COX-2 inhibitors: basic science and clinical applications. | Frontiers in bioscience : a journal and virtual library 20040901 |
Simultaneously targeting epidermal growth factor receptor tyrosine kinase and cyclooxygenase-2, an efficient approach to inhibition of squamous cell carcinoma of the head and neck. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040901 |
Vitamin E analog alpha-TEA and celecoxib alone and together reduce human MDA-MB-435-FL-GFP breast cancer burden and metastasis in nude mice. | Breast cancer research and treatment 20040901 |
[A case report of metastatic pancreatic cancer that responded remarkably to the combination of thalidomide, celecoxib and irinotecan]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040901 |
Effects of a prior-authorization policy for celecoxib on medical service and prescription drug use in a managed care Medicaid population. | Clinical therapeutics 20040901 |
Use of gastrointestinal preventive therapy among elderly persons receiving antiarthritic agents in Nova Scotia, Canada. | The American journal of geriatric pharmacotherapy 20040901 |
Celecoxib enhances brain tumour cell radiosensitivity leading to massive tumour necrosis. | Annals of the Academy of Medicine, Singapore 20040901 |
Pharmacological characterisation of the rat brachial plexus avulsion model of neuropathic pain. | Brain research 20040827 |
Clinical implication of expression of cyclooxygenase-2 and peroxisome proliferator activated-receptor gamma in epithelial ovarian tumours. | British journal of cancer 20040816 |
Targeting the epidermal growth factor receptor. | British journal of cancer 20040802 |
Chemopreventive activity of parthenolide against UVB-induced skin cancer and its mechanisms. | Carcinogenesis 20040801 |
Patient Preference for Placebo, Acetaminophen (paracetamol) or Celecoxib Efficacy Studies (PACES): two randomised, double blind, placebo controlled, crossover clinical trials in patients with knee or hip osteoarthritis. | Annals of the rheumatic diseases 20040801 |
Promoter hypermethylation silences cyclooxygenase-2 (Cox-2) and regulates growth of human hepatocellular carcinoma cells. | Laboratory investigation; a journal of technical methods and pathology 20040801 |
Is there an inhibitory effect of COX-2 inhibitors on bone healing? | Pharmacological research 20040801 |
Hypertension associated with therapies to treat arthritis and pain. | Hypertension (Dallas, Tex. : 1979) 20040801 |
Relationship between COX-2 specific inhibitors and hypertension. | Hypertension (Dallas, Tex. : 1979) 20040801 |
Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates TNF-induced NF-kappa B activation through inhibition of activation of I kappa B alpha kinase and Akt in human non-small cell lung carcinoma: correlation with suppression of COX-2 synthesis. | Journal of immunology (Baltimore, Md. : 1950) 20040801 |
Interleukin-1beta-induced mucin production in human airway epithelium is mediated by cyclooxygenase-2, prostaglandin E2 receptors, and cyclic AMP-protein kinase A signaling. | Molecular pharmacology 20040801 |
COX-2 inhibitors as adjunctive therapy in schizophrenia. | Expert opinion on investigational drugs 20040801 |
First and second generations of COX-2 selective inhibitors. | Mini reviews in medicinal chemistry 20040801 |
COX-2 selective inhibitors, carbonic anhydrase inhibition and anticancer properties of sulfonamides belonging to this class of pharmacological agents. | Mini reviews in medicinal chemistry 20040801 |
Celecoxib effectively treats patients with acute shoulder tendinitis/bursitis. | The Journal of rheumatology 20040801 |
Comparison of the anti-proliferation and apoptosis-induction activities of sulindac, celecoxib, curcumin, and nifedipine in mismatch repair-deficient cell lines. | Journal of the Formosan Medical Association = Taiwan yi zhi 20040801 |
[Influence of non-selective and cyclooxygenase-II-selective cyclooxygenase-inhibitors on primary human osteoblasts]. | Zentralblatt fur Chirurgie 20040801 |
Celecoxib induces functional recovery after intracerebral hemorrhage with reduction of brain edema and perihematomal cell death. | Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20040801 |
Improvement of physical stability and dissolution rate of celecoxib suspensions by complexation with beta-cyclodextrins. | Die Pharmazie 20040801 |
Risk of Upper Gastrointestinal Injury and Events in Patients Treated With Cyclooxygenase (COX)-1/COX-2 Nonsteroidal Antiinflammatory Drugs (NSAIDs), COX-2 Selective NSAIDs, and Gastroprotective Cotherapy: An Appraisal of the Literature. | Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20040801 |
Design, synthesis, and structure-activity relationship studies of 3,4,6-triphenylpyran-2-ones as selective cyclooxygenase-2 inhibitors. | Journal of medicinal chemistry 20040729 |
Inhibition of cyclooxygenase-2 activity in head and neck cancer cells by genistein. | Cancer letters 20040728 |
Reduction of tumor progression and paraneoplastic syndrome development in murine lung adenocarcinoma by nonsteroidal antiinflammatory drugs. | International journal of cancer 20040720 |
Celecoxib, a cyclooxygenase-2 inhibitor, reduces neointimal hyperplasia through inhibition of Akt signaling. | Circulation 20040720 |
Antimetastatic activity of a cyclooxygenase-2 inhibitor. | British journal of cancer 20040719 |
Effects of the selective COX-2 inhibitors celecoxib and rofecoxib on human vascular cells. | Biochemical pharmacology 20040715 |
Pruned receptor surface models and pharmacophores for three-dimensional database searching. | Journal of medicinal chemistry 20040715 |
Cyclooxygenase (COX)-2 inhibitor celecoxib abrogates activation of cigarette smoke-induced nuclear factor (NF)-kappaB by suppressing activation of IkappaBalpha kinase in human non-small cell lung carcinoma: correlation with suppression of cyclin D1, COX-2, and matrix metalloproteinase-9. | Cancer research 20040715 |
Her2/neu expression predicts the response to antiaromatase neoadjuvant therapy in primary breast cancer: subgroup analysis from celecoxib antiaromatase neoadjuvant trial. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040715 |
Effect of nonsteroidal anti-inflammatory drugs on beta-catenin protein levels and catenin-related transcription in human colorectal cancer cells. | British journal of cancer 20040705 |
Inhibitory effect of cyclo-oxygenase-2 inhibitor on the production of matrix metalloproteinases in rheumatoid fibroblast-like synoviocytes. | Rheumatology international 20040701 |
Lipopolysaccharide-induced paw edema model for detection of cytokine modulating anti-inflammatory agents. | International immunopharmacology 20040701 |
Effects of cyclooxygenase 2 inhibitors on biological traits of nasopharyngeal carcinoma cells. | Acta pharmacologica Sinica 20040701 |
Pilot study of celecoxib and infusional 5-fluorouracil as second-line treatment for advanced pancreatic carcinoma. | Cancer 20040701 |
The cost-effectiveness of aspirin versus cyclooxygenase-2-selective inhibitors for colorectal carcinoma chemoprevention in healthy individuals. | Cancer 20040701 |
Anti-cancer effects of COX-2 inhibitors and their correlation with angiogenesis and invasion in gastric cancer. | World journal of gastroenterology 20040701 |
Efficacy of celecoxib, a COX-2-specific inhibitor, and naproxen in the management of acute ankle sprain: results of a double-blind, randomized controlled trial. | Clinical journal of sport medicine : official journal of the Canadian Academy of Sport Medicine 20040701 |
Attenuation of mechanical allodynia by clinically utilized drugs in a rat chemotherapy-induced neuropathic pain model. | Pain 20040701 |
Neuronal expression of cyclooxygenase-2, a pro-inflammatory protein, in the hippocampus of patients with schizophrenia. | Progress in neuro-psychopharmacology & biological psychiatry 20040701 |
Therapeutic interchange involving replacement of rofecoxib or celecoxib with valdecoxib. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20040701 |
Acute generalized exanthematous pustulosis caused by celecoxib. | Journal of the Formosan Medical Association = Taiwan yi zhi 20040701 |
Gastrointestinal side-effects of traditional non-steroidal anti-inflammatory drugs and new formulations. | Alimentary pharmacology & therapeutics 20040701 |
Utilization patterns of cyclooxygenase-2 inhibitors among patients with arthritis in a managed care setting. | Managed care interface 20040701 |
COX-2 inhibitory treatment in chronic lymphocytic leukemia: a preliminary clinical study. | Leukemia & lymphoma 20040701 |
[Cyclooxygenase-2 inhibitors in postoperative pain management]. | Agri : Agri (Algoloji) Dernegi'nin Yayin organidir = The journal of the Turkish Society of Algology 20040701 |
Effects of celecoxib on high-sensitivity C-reactive protein in chronic peritoneal dialysis patients. | Renal failure 20040701 |
The spectrum of gastrointestinal toxicity and effect on disease activity of selective cyclooxygenase-2 inhibitors in patients with inflammatory bowel disease. | Inflammatory bowel diseases 20040701 |
Gastrointestinal-related complications in a long-term care population taking NSAIDs versus COX-2 inhibitor therapy. | The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists 20040701 |
Isolation, synthesis and characterization of impurities in celecoxib, a COX-2 inhibitor. | Journal of pharmaceutical and biomedical analysis 20040629 |
Nonsteroidal anti-inflammatory drugs increase expression of inducible COX-2 isoform of cyclooxygenase in spinal cord of rats with adjuvant induced inflammation. | Brain research. Molecular brain research 20040618 |
From the cyclooxygenase-2 inhibitor celecoxib to a novel class of 3-phosphoinositide-dependent protein kinase-1 inhibitors. | Cancer research 20040615 |
Phase II study of celecoxib and trastuzumab in metastatic breast cancer patients who have progressed after prior trastuzumab-based treatments. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040615 |
Cyclooxygenase as a target in lung cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040615 |
Over-the-counter pain reliever and aspirin use within a sample of long-term cyclooxygenase 2 users. | Archives of internal medicine 20040614 |
Cooperation between aspirin-triggered lipoxin and nitric oxide (NO) mediates antiadhesive properties of 2-(Acetyloxy)benzoic acid 3-(nitrooxymethyl)phenyl ester (NCX-4016) (NO-aspirin) on neutrophil-endothelial cell adherence. | The Journal of pharmacology and experimental therapeutics 20040601 |
Formation and antiproliferative effect of prostaglandin E(3) from eicosapentaenoic acid in human lung cancer cells. | Journal of lipid research 20040601 |
Vascular and cellular responses to pro-inflammatory stimuli in rat dental pulp. | Archives of oral biology 20040601 |
Pulmonary edema and possible pneumonitis associated with celecoxib. | The Annals of pharmacotherapy 20040601 |
Systematic review of the analgesic efficacy and tolerability of COX-2 inhibitors in post-operative pain control. | Journal of clinical pharmacy and therapeutics 20040601 |
Reduced incidence of gastroduodenal ulcers associated with lumiracoxib compared with ibuprofen in patients with rheumatoid arthritis. | Alimentary pharmacology & therapeutics 20040601 |
Blood pressure destabilization and edema among 8538 users of celecoxib, rofecoxib, and nonselective nonsteroidal antiinflammatory drugs (NSAID) and nonusers of NSAID receiving ordinary clinical care. | The Journal of rheumatology 20040601 |
Treatment with 5-fluorouracil and celecoxib displays synergistic regression of ultraviolet light B-induced skin tumors. | The Journal of investigative dermatology 20040601 |
Cell proliferation and apoptotic indices predict adenoma regression in a placebo-controlled trial of celecoxib in familial adenomatous polyposis patients. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20040601 |
Celecoxib-induced photoallergic drug eruption. | International journal of dermatology 20040601 |
[A case of advanced pancreatic cancer with remarkable response to thalidomide, celecoxib and gemcitabine]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040601 |
Involvement of prostaglandins in inflammation induced by latex of Calotropis procera. | Mediators of inflammation 20040601 |
Effects of celecoxib on acid-challenged gastric mucosa of rats: comparison with metamizol and piroxicam. | Digestive diseases and sciences 20040601 |
Tolerability of three selective cyclo-oxygenase-2 inhibitors, meloxicam, celecoxib and rofecoxib in NSAID-sensitive patients. | European annals of allergy and clinical immunology 20040601 |
Glucosamine for osteoarthritis: part I, review of the clinical evidence. | Medicine and health, Rhode Island 20040601 |
[Effects of celecoxib on the proliferation and apoptosis of human colorectal cancer cell line HT-29]. | Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20040601 |
Prostaglandins: modulators of inflammation and cardiovascular risk. | Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20040601 |
Cyclo-oxygenase-2 inhibitors versus non-selective non-steroidal anti-inflammatory drugs and congestive heart failure outcomes in elderly patients: a population-based cohort study. | Lancet (London, England) 20040529 |
Determination of celecoxib in human plasma by high-performance liquid chromatography. | Journal of pharmaceutical and biomedical analysis 20040528 |
[Celecoxib in the symptomatic treatment of active osteo- or rheumatoid arthritis. Results of a post-marketing surveillance]. | Deutsche medizinische Wochenschrift (1946) 20040521 |
Combination of a poxvirus-based vaccine with a cyclooxygenase-2 inhibitor (celecoxib) elicits antitumor immunity and long-term survival in CEA.Tg/MIN mice. | Cancer research 20040515 |
Differential up-regulation of cytosolic and membrane-bound heat shock protein 70 in tumor cells by anti-inflammatory drugs. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040515 |
Relationship between selective cyclooxygenase-2 inhibitors and acute myocardial infarction in older adults. | Circulation 20040504 |
2,3-diarylpyran-4-ones: a new series of selective cyclooxygenase-2 inhibitors. | Bioorganic & medicinal chemistry letters 20040503 |
Celecoxib inhibits phorbol ester-induced expression of COX-2 and activation of AP-1 and p38 MAP kinase in mouse skin. | Carcinogenesis 20040501 |
Celecoxib 200 mg q.d. is efficacious in the management of osteoarthritis of the knee or hip regardless of the time of dosing. | Rheumatology (Oxford, England) 20040501 |
The balloon catheter induces an increase in contralateral carotid artery reactivity to angiotensin II and phenylephrine. | British journal of pharmacology 20040501 |
Nonsteroidal anti-inflammatory drugs and aspirin for the prevention of colorectal adenomas and cancer: a systematic review. | Diseases of the colon and rectum 20040501 |
Environmental, pharmacological, and genetic modulation of the HD phenotype in transgenic mice. | Experimental neurology 20040501 |
A systematic review of COX-2 inhibitors compared with traditional NSAIDs, or different COX-2 inhibitors for post-operative pain. | Acta anaesthesiologica Scandinavica 20040501 |
COX-2 dependent PGE(2) downregulates alpha(v) integrin expression via the EP(3) receptor in cultured mesangial cells. | Journal of clinical pathology 20040501 |
Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040501 |
Celecoxib can prevent tumor growth and distant metastasis in postoperative setting. | Cancer research 20040501 |
Suppression of prostate carcinogenesis by dietary supplementation of celecoxib in transgenic adenocarcinoma of the mouse prostate model. | Cancer research 20040501 |
Drug switching patterns among patients with rheumatoid arthritis and osteoarthritis using COX-2 specific inhibitors and non-specific NSAIDs. | Pharmacoepidemiology and drug safety 20040501 |
Changes in osteoarthritis management by general practitioners in the COX2-inhibitor era-concomitant gastroprotective therapy. | Joint, bone, spine : revue du rhumatisme 20040501 |
NSAIDs: gastroprotection or selective COX-2 inhibitor? | Palliative medicine 20040501 |
[Cyclooxygenase 2 and breast cancer. From biological concepts to therapeutic trials]. | Bulletin du cancer 20040501 |
[Cyclooxygenase 2 inhibitors and lung carcinoma]. | Bulletin du cancer 20040501 |
[Safety of selective inhibitors of inducible cyclooxygenase-2 taken for a long period]. | Bulletin du cancer 20040501 |
[Analgesic effects of cyclooxygenase 2 inhibitors]. | Bulletin du cancer 20040501 |
[Etoricoxib (Arcoxia)]. | Revue medicale de Liege 20040501 |
[Cyclooxygenase 2 and breast cancer. From biological concepts to clinical trials]. | Bulletin du cancer 20040501 |
[Cyclooxygenase 2 inhibitors and lung carcinoma]. | Bulletin du cancer 20040501 |
[Safety of selective cyclooxygenase-2 inhibitors taken for a long time]. | Bulletin du cancer 20040501 |
[Analgesic effects of cyclooxygenase 2 inhibitors]. | Bulletin du cancer 20040501 |
Synthesis and selective cyclooxygenase-2 inhibitory activity of a series of novel, nitric oxide donor-containing pyrazoles. | Journal of medicinal chemistry 20040422 |
Design of acyclic triaryl olefins: a new class of potent and selective cyclooxygenase-2 (COX-2) inhibitors. | Bioorganic & medicinal chemistry letters 20040419 |
Cyclooxygenase-2 (COX-2)-dependent and -independent anticarcinogenic effects of celecoxib in human colon carcinoma cells. | Biochemical pharmacology 20040415 |
Serum proteomic profiles suggest celecoxib-modulated targets and response predictors. | Cancer research 20040415 |
Correspondence re: M. V. Swamy et al., Inhibition of COX-2 in colon cancer cell lines by celecoxib increases the nuclear localization of active p53. Cancer Res 2003;63:5239-42. | Cancer research 20040415 |
Preclinical evaluation of the nonsteroidal anti-inflammatory agent celecoxib on malignant mesothelioma chemoprevention. | International journal of cancer 20040410 |
[Renal and cardiovascular effects of non-steroidal anti-inflammatories and selective cox 2 inhibitors]. | Presse medicale (Paris, France : 1983) 20040410 |
[Selective cox-2 inhibitors. Better tolerance than NSAID plus antacid]. | MMW Fortschritte der Medizin 20040408 |
Methanesulfonamide group at position-4 of the C-5-phenyl ring of 1,5-diarylpyrazole affords a potent class of cyclooxygenase-2 (COX-2) inhibitors. | Bioorganic & medicinal chemistry letters 20040405 |
Hepatotoxicity induced by celecoxib and amlodipine. | Swiss medical weekly 20040403 |
Growth inhibition of breast epithelial cells by celecoxib is associated with upregulation of insulin-like growth factor binding protein-3 expression. | Biochemical and biophysical research communications 20040402 |
Overexpression of cyclooxygenase-2 is associated with radioresistance in oral squamous cell carcinoma. | Oral oncology 20040401 |
Involvement of bradykinin, cytokines, sympathetic amines and prostaglandins in formalin-induced orofacial nociception in rats. | British journal of pharmacology 20040401 |
Acute tubulointerstitial nephritis associated with celecoxib. | Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20040401 |
COX-2-selective inhibitors and the risk of upper gastrointestinal bleeding in high-risk patients with previous gastrointestinal diseases: a population-based case-control study. | Alimentary pharmacology & therapeutics 20040401 |
Mechanisms of nonsteroidal anti-inflammatory drug-induced gastrointestinal injury and repair: a window of opportunity for cyclooxygenase-inhibiting nitric oxide donors. | Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20040401 |
Celecoxib-induced apoptosis in rat cholangiocarcinoma cells mediated by Akt inactivation and Bax translocation. | Hepatology (Baltimore, Md.) 20040401 |
Tramadol pharmacokinetics and its possible interactions with cyclooxygenase 2-selective nonsteroidal anti-inflammatory drugs. | Clinical pharmacology and therapeutics 20040401 |
A randomized, controlled comparison of ibuprofen at the maximal over-the-counter dose compared with prescription-dose celecoxib on upper gastrointestinal mucosal injury. | Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 20040401 |
Impact of selective cyclooxygenase-2 inhibitors on anti-ulcer medication and non-steroidal anti-inflammatory drug use in patients with rheumatic disease. | Internal medicine journal 20040401 |
[Report of two cases with pleural effusion and ascites that responded dramatically to the combination of thalidomide, celecoxib, irinotecan, and CDDP infused in thoracic and abdominal cavities]. | Gan to kagaku ryoho. Cancer & chemotherapy 20040401 |
Gastric effects of the selective cyclooxygenase-2 inhibitor, celecoxib, in the rat. | Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 20040401 |
Effect of celecoxib on renal function in cirrhotic patients with ascites. A pilot study. | Scandinavian journal of gastroenterology 20040401 |
[Results of treatment with COX-2 inhibitors and lanreotide in a patient with Menetrier's hypertrophic gastropathy]. | Gastroenterologie clinique et biologique 20040401 |
[Clinical evaluation of celecoxib in treating type IIIA chronic prostatitis]. | Zhonghua nan ke xue = National journal of andrology 20040401 |
Multiple roles of COX-2 in tumor angiogenesis: a target for antiangiogenic therapy. | Seminars in oncology 20040401 |
The role of COX-2 inhibition in breast cancer treatment and prevention. | Seminars in oncology 20040401 |
COX-2 inhibition and lung cancer. | Seminars in oncology 20040401 |
COX-2 inhibition and colorectal cancer. | Seminars in oncology 20040401 |
Invasive and angiogenic phenotype of MCF-7 human breast tumor cells expressing human cyclooxygenase-2. | Prostaglandins & other lipid mediators 20040401 |
[Selective COX-2 inhibitors: do they retain any gastroduodenal toxicity]. | Gastroenterologie clinique et biologique 20040401 |
Induction of microsomal prostaglandin E synthase-1 in human gingival fibroblasts. | Inflammation 20040401 |
Phosphorylation status of c-Kit and Epo receptors, and the presence of wild-type p53 confer in vitro resistance of murine erythroleukemic cells to Celecoxib. | Oncogene 20040325 |
Effect of celecoxib on Ca2+ movement and cell proliferation in human osteoblasts. | Biochemical pharmacology 20040315 |
Lessons from early large-scale adoption of celecoxib and rofecoxib by Australian general practitioners. | The Medical journal of Australia 20040315 |
Celecoxib inhibits vascular endothelial growth factor expression in and reduces angiogenesis and metastasis of human pancreatic cancer via suppression of Sp1 transcription factor activity. | Cancer research 20040315 |
Preferential expression of hPGFS in primary SCCHN and tumour cell lines derived from respiratory and digestive organs. | British journal of cancer 20040308 |
[Capsule endoscopy study of gastrointestinal tolerance. Coxibes superior to NSAID plus antacid]. | MMW Fortschritte der Medizin 20040304 |
Aromatase inhibitors for chemoprevention. | Best practice & research. Clinical endocrinology & metabolism 20040301 |
Inhibition of cyclooxygenase-2 by celecoxib reverses tumor-induced wasting. | The Journal of pharmacology and experimental therapeutics 20040301 |
Effects of COX inhibition on blood pressure and kidney function in ACE inhibitor-treated blacks and hispanics. | Hypertension (Dallas, Tex. : 1979) 20040301 |
Drug interaction with T-cell receptors: T-cell receptor density determines degree of cross-reactivity. | The Journal of allergy and clinical immunology 20040301 |
Assessment of cyclooxygense-2 expression with 99mTc-labeled celebrex. | Anti-cancer drugs 20040301 |
Solubility enhancement of celecoxib using beta-cyclodextrin inclusion complexes. | European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20040301 |
The cyclooxygenase-2 inhibitor celecoxib blocks phosphorylation of Akt and induces apoptosis in human cholangiocarcinoma cells. | Molecular cancer therapeutics 20040301 |
Uptake of COX-2 selective inhibitors and influence on NSAID prescribing in Northern Ireland. | Pharmacoepidemiology and drug safety 20040301 |
Effects of bile from patient with transduodenal sphincteroplasty on the growth of human cholangiocarcinoma cell line. | Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih 20040301 |
Isoflurane produces delayed preconditioning against myocardial ischemia and reperfusion injury: role of cyclooxygenase-2. | Anesthesiology 20040301 |
Cyclooxygenase-2 mediates ischemic, anesthetic, and pharmacologic preconditioning in vivo. | Anesthesiology 20040301 |
The preemptive analgesic effect of celecoxib for day-case diagnostic laparoscopy. | Journal of the Medical Association of Thailand = Chotmaihet thangphaet 20040301 |
Analgesic efficacy of a single dose of lumiracoxib compared with rofecoxib, celecoxib and placebo in the treatment of post-operative dental pain. | International journal of clinical practice 20040301 |
Cardiovascular effects of selective cyclooxygenase-2 inhibitors. | Expert review of cardiovascular therapy 20040301 |
Beta-cyclodextrin complexes of celecoxib: molecular-modeling, characterization, and dissolution studies. | AAPS pharmSci 20040301 |
Cyclooxygenase-2-mediated prostaglandin E2 production in mesenteric lymph nodes and in cultured macrophages and dendritic cells after infection with Salmonella. | Journal of immunology (Baltimore, Md. : 1950) 20040215 |
Cyclooxygenase-2 in the pathogenesis of murine cerebral malaria. | The Journal of infectious diseases 20040215 |
Cyclooxygenase-2 promotes human cholangiocarcinoma growth: evidence for cyclooxygenase-2-independent mechanism in celecoxib-mediated induction of p21waf1/cip1 and p27kip1 and cell cycle arrest. | Cancer research 20040215 |
3-phosphoinositide-dependent protein kinase-1/Akt signaling represents a major cyclooxygenase-2-independent target for celecoxib in prostate cancer cells. | Cancer research 20040215 |
In vitro structure-activity relationship and in vivo studies for a novel class of cyclooxygenase-2 inhibitors: 5-aryl-2,2-dialkyl-4-phenyl-3(2H)furanone derivatives. | Journal of medicinal chemistry 20040212 |
Simultaneous expression of COX-2 and mPGES-1 in mouse gastrointestinal hamartomas. | British journal of cancer 20040209 |
Cyclooxygenase-2 selective inhibition with NS-398 suppresses proliferation and invasiveness and delays liver metastasis in colorectal cancer. | British journal of cancer 20040209 |
Cerivastatin inhibits proliferation of interleukin-1 beta-induced rat mesangial cells by enhanced formation of nitric oxide. | European journal of pharmacology 20040206 |
Lessons from early large-scale adoption of celecoxib and rofecoxib by Australian general practitioners. | The Medical journal of Australia 20040202 |
Studies on the anti-inflammatory effect of fluoxetine in the rat. | Pharmacological research 20040201 |
Evaluation of the anti-inflammatory, anti-nociceptive and gastric effects of Ginkgo biloba in the rat. | Pharmacological research 20040201 |
Increased cyclooxygenase-2 (COX-2): a potential role in the pathogenesis of lymphoma. | Leukemia research 20040201 |
Nonsteroidal anti-inflammatory drugs and cyclooxygenase-2 selective inhibitors for prostate cancer chemoprevention. | The Journal of urology 20040201 |
Intracranial inhibition of glioma cell growth by cyclooxygenase-2 inhibitor celecoxib. | Oncology reports 20040201 |
Additive neuroprotective effects of creatine and cyclooxygenase 2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis. | Journal of neurochemistry 20040201 |
Chemoprevention of gastric cancer by celecoxib in rats. | Gut 20040201 |
Effects of a selective cyclooxygenase-2 inhibitor on cancer cells in vitro. | Cancer biology & therapy 20040201 |
Potentiation of tumor response to radiation or chemoradiation by selective cyclooxygenase-2 enzyme inhibitors. | International journal of radiation oncology, biology, physics 20040201 |
Licofelone--clinical update on a novel LOX/COX inhibitor for the treatment of osteoarthritis. | Rheumatology (Oxford, England) 20040201 |
Longer use of COX-2-specific inhibitors compared to nonspecific nonsteroidal antiinflammatory drugs: a longitudinal study of 3639 patients in community practice. | The Journal of rheumatology 20040201 |
A pilot study of use of the cyclooxygenase-2 inhibitor celecoxib in recurrent prostate cancer after definitive radiation therapy or radical prostatectomy. | BJU international 20040201 |
Inhibition of rat mammary gland carcinogenesis by simultaneous targeting of cyclooxygenase-2 and peroxisome proliferator-activated receptor gamma. | Cancer research 20040201 |
NSAIDs and chemoprevention. | Current cancer drug targets 20040201 |
Warfarin and celecoxib interaction in the setting of cytochrome P450 (CYP2C9) polymorphism with bleeding complication. | Postgraduate medical journal 20040201 |
Effects of a high-selenium yeast supplement on celecoxib plasma levels: a randomized phase II trial. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20040201 |
Improvement strategies for molecular targeting: Cyclooxygenase-2 inhibitors as radiosensitizers for non-small cell lung cancer. | Seminars in oncology 20040201 |
Side effects of conventional nonsteroidal anti-inflammatory drugs and celecoxib: more similarities than differences. | Southern medical journal 20040201 |
Modulation of cyclooxygenase-2 activities by the combined action of celecoxib and decosahexaenoic acid: novel strategies for colon cancer prevention and treatment. | Molecular cancer therapeutics 20040201 |
COX-2 inhibition as a treatment approach in schizophrenia: immunological considerations and clinical effects of celecoxib add-on therapy. | European archives of psychiatry and clinical neuroscience 20040201 |
Bony metastases of anaplastic oligodendroglioma respond to temozolomide. | The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 20040201 |
Cyclooxygenase-2 inhibitors: do they have a role in emergency department prescribing? | Emergency medicine Australasia : EMA 20040201 |
Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition. | Journal of medicinal chemistry 20040129 |
[Homeopathy suppresses COX- and LOX activity. Soft therapy for arthrosis ills]. | MMW Fortschritte der Medizin 20040129 |
Determination of celecoxib in human plasma using solid-phase extraction and high-performance liquid chromatography. | Journal of pharmaceutical and biomedical analysis 20040127 |
COX-2 expression is associated with an aggressive phenotype in ductal carcinoma in situ. | British journal of cancer 20040126 |
Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with the antipsychotic drug sulpiride. | Bioorganic & medicinal chemistry letters 20040119 |
Polar substitutions in the benzenesulfonamide ring of celecoxib afford a potent 1,5-diarylpyrazole class of COX-2 inhibitors. | Bioorganic & medicinal chemistry letters 20040119 |
Celecoxib simulates respiratory burst through pertussis toxin-sensitive G-protein, a possible signal for beta 2-integrin expression on human neutrophils. | European journal of pharmacology 20040119 |
First-line endocrine treatment of breast cancer: aromatase inhibitor or antioestrogen? | British journal of cancer 20040112 |
Prostate cancer and use of nonsteroidal anti-inflammatory drugs: systematic review and meta-analysis. | British journal of cancer 20040112 |
Discovery of a potent, selective and orally active canine COX-2 inhibitor, 2-(3-difluoromethyl-5-phenyl-pyrazol-1-yl)-5-methanesulfonyl-pyridine. | Bioorganic & medicinal chemistry letters 20040105 |
The effect of COX-2 inhibitors on periprosthetic osteolysis. | Biomaterials 20040101 |
Pharmacological characterisation of a rat model of incisional pain. | British journal of pharmacology 20040101 |
Genetic deficiency or pharmacological inhibition of cyclooxygenase-1 or -2 induces mouse keratinocyte differentiation in vitro and in vivo. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040101 |
PGE2 and IL-6 production by fibroblasts in response to titanium wear debris particles is mediated through a Cox-2 dependent pathway. | Journal of orthopaedic research : official publication of the Orthopaedic Research Society 20040101 |
Aspirin, but not NO-releasing aspirin (NCX-4016), interacts with selective COX-2 inhibitors to aggravate gastric damage and inflammation. | American journal of physiology. Gastrointestinal and liver physiology 20040101 |
Differences between clinical trials and postmarketing use. | British journal of clinical pharmacology 20040101 |
Cyclooxygenase 2 selective inhibitor induced bowel stricture: a case report. | Gut 20040101 |
Modulation of beta-amyloid metabolism by non-steroidal anti-inflammatory drugs in neuronal cell cultures. | Journal of neurochemistry 20040101 |
Cyclooxygenase inhibition in nerve-injury- and TNF-induced hyperalgesia in the rat. | Experimental neurology 20040101 |
Efficacy and safety of tramadol/acetaminophen tablets (Ultracet) as add-on therapy for osteoarthritis pain in subjects receiving a COX-2 nonsteroidal antiinflammatory drug: a multicenter, randomized, double-blind, placebo-controlled trial. | The Journal of rheumatology 20040101 |
Effects of celecoxib, medroxyprogesterone, and dietary intervention on systemic syndromes in patients with advanced lung adenocarcinoma: a pilot study. | Journal of pain and symptom management 20040101 |
Effect of COX-2-specific inhibition on fracture-healing in the rat femur. | The Journal of bone and joint surgery. American volume 20040101 |
Pharmacological treatments for persistent non-malignant pain in older persons. | Drugs & aging 20040101 |
Celecoxib versus indomethacin in the prevention of heterotopic ossification after total hip arthroplasty. | The Journal of arthroplasty 20040101 |
Comparison of nonselective cyclo-oxygenase (COX) inhibitor and selective COX-2 inhibitors on preimplantation loss, postimplantation loss and duration of gestation: an experimental study. | Contraception 20040101 |
Differential effects of selective COX-2 inhibitors on cell cycle regulation and proliferation of glioblastoma cell lines. | Cancer biology & therapy 20040101 |
Synergy between celecoxib and radiotherapy results from inhibition of cyclooxygenase-2-derived prostaglandin E2, a survival factor for tumor and associated vasculature. | Cancer research 20040101 |
Effects of dexamethasone or celecoxib on biliary toxicity after hepatic arterial infusion of 5-fluorodeoxyuridine in a canine model. | Cancer research 20040101 |
Celecoxib but not rofecoxib inhibits the growth of transformed cells in vitro. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040101 |
Prevention strategies with aromatase inhibitors. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040101 |
Neoadjuvant endocrine therapy as a drug development strategy. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040101 |
Aseptic meningitis possibly associated with celecoxib. | The Annals of pharmacotherapy 20040101 |
Benefit-risk assessment of rofecoxib in the treatment of osteoarthritis. | Drug safety 20040101 |
Clinical pharmacology of novel selective COX-2 inhibitors. | Current pharmaceutical design 20040101 |
[Non-steroidal anti-inflammatory agents for chemoprevention of colorectal polyps: a meta-analysis]. | Zhonghua nei ke za zhi 20040101 |
Renal effects of etoricoxib and comparator nonsteroidal anti-inflammatory drugs in controlled clinical trials. | Clinical therapeutics 20040101 |
A cross-media content analysis of motivational themes in direct-to-consumer prescription drug advertising. | Clinical therapeutics 20040101 |
Cyclooxygenase-2 inhibitors in glioma therapy. | American journal of therapeutics 20040101 |
Role of cyclooxygenase-2 in colorectal cancer. | Cancer metastasis reviews 20040101 |
Triptolide, an active compound identified in a traditional Chinese herb, induces apoptosis of rheumatoid synovial fibroblasts. | BMC pharmacology 20040101 |
[Toxic epidermal necrolysis and celecoxib (Celebrex)]. | Annales de dermatologie et de venereologie 20040101 |
Cutaneous reaction to oral celecoxib with positive patch test. | Contact dermatitis 20040101 |
Post-treatment, but not pre-treatment, with the selective cyclooxygenase-2 inhibitor celecoxib markedly enhances functional recovery from kainic acid-induced neurodegeneration. | Neuroscience 20040101 |
Celecoxib: a potent cyclooxygenase-2 inhibitor in cancer prevention. | Cancer detection and prevention 20040101 |
Modulation of intracellular calcium signaling and mitochondrial function in cultured osteoblastic cells by dexamethasone and celecoxib during mechanical stimulation. | Clinical and experimental rheumatology 20040101 |
Analgesics for acute pain: Meeting the United States Food and Drug Administration's requirements for proof of efficacy. | The Clinical journal of pain 20040101 |
Update on nonprescription pain relievers for dental pain. | General dentistry 20040101 |
S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495]. | BMC musculoskeletal disorders 20040101 |
Non steroidal anti-inflammatory drugs (NSAID) and Aspirin for preventing colorectal adenomas and carcinomas. | The Cochrane database of systematic reviews 20040101 |
Do COX-2 inhibitors reduce renal fibrosis? | Journal of hypertension 20040101 |
Chronic cyclooxygenase-2 inhibition does not alter blood pressure and kidney function in renovascular hypertensive rats. | Journal of hypertension 20040101 |
[Bupivacaine for continuous interscalene brachial plexus analgesia after shoulder surgery]. | Medicina (Kaunas, Lithuania) 20040101 |
Spontaneous reports of hypertension leading to hospitalisation in association with rofecoxib, celecoxib, nabumetone and oxaprozin. | Drugs & aging 20040101 |
A mechanistic perspective on the specificity and extent of COX-2 inhibition in pregnancy. | Drug safety 20040101 |
Do some inhibitors of COX-2 increase the risk of thromboembolic events?: Linking pharmacology with pharmacoepidemiology. | Drug safety 20040101 |
Upper gastrointestinal bleeding associated with the use of NSAIDs: newer versus older agents. | Drug safety 20040101 |
Lithium intoxication as a result of an interaction with rofecoxib. | The Annals of pharmacotherapy 20040101 |
[Capecitabine and irinotecan]. | I supplementi di Tumori : official journal of Societa italiana di cancerologia ... [et al.] 20040101 |
COX-2 inhibitors: a CLASS act or Just VIGORously promoted. | MedGenMed : Medscape general medicine 20040101 |
Diosgenin, a plant steroid, induces apoptosis in human rheumatoid arthritis synoviocytes with cyclooxygenase-2 overexpression. | Arthritis research & therapy 20040101 |
Expanding the armamentarium for the spondyloarthropathies. | Arthritis research & therapy 20040101 |
Acute generalized exanthematic pustulosis: a case and an overview of side effects affecting the skin caused by celecoxib and other COX-2 inhibitors reported so far. | Dermatology (Basel, Switzerland) 20040101 |
Cancer, oncogenes and signal transduction. | Genome biology 20040101 |
Proteasome inhibitors: their effects on arachidonic acid release from cells in culture and arachidonic acid metabolism in rat liver cells. | BMC pharmacology 20040101 |
Impact on drug costs and utilization of a clinical pharmacist in a multisite primary care medical group. | Journal of managed care pharmacy : JMCP 20040101 |
Tamoxifen and the Rafoxifene analog LY117018: their effects on arachidonic acid release from cells in culture and on prostaglandin I2 production by rat liver cells. | BMC cancer 20040101 |
Encouraging physician appropriate prescribing of non-steroidal anti-inflammatory therapies: protocol of a randomized controlled trial [ISRCTN43532635]. | BMC health services research 20040101 |
[Therapeutic advances with coxibs: few certainties and a lot of doubts]. | Therapie 20040101 |
[Coxibs, which real therapeutic advance?: Recent pharmacoepidemiological data]. | Therapie 20040101 |
Lumiracoxib. | Drugs 20040101 |
Tackling publication bias and selective reporting in health informatics research: register your eHealth trials in the International eHealth Studies Registry. | Journal of medical Internet research 20040101 |
Inhibition of cyclooxygenase-2 by diallyl sulfides (DAS) in HEK 293T cells. | Journal of applied genetics 20040101 |
Anti-inflammatory therapy with a COX-2 inhibitor in Tourette's syndrome. | Inflammopharmacology 20040101 |
Control of pulmonary metastases of rat mammary cancer by inhibition of uPA and COX-2, singly and in combination. | Clinical & experimental metastasis 20040101 |
Linking pharmacovigilance with pharmacogenetics. | Drug safety 20040101 |
Effects and mechanism of the selective COX-2 inhibitor, celecoxib, on rat colitis induced by trinitrobenzene sulfonic acid. | Chinese journal of digestive diseases 20040101 |
Celecoxib incorporated chitosan microspheres: in vitro and in vivo evaluation. | Journal of drug targeting 20040101 |
Novel opportunities in the treatment and prevention of scarring. | Journal of cutaneous medicine and surgery 20040101 |
Anti-inflammatory effects of selective COX-2 inhibitors. | Polish journal of pharmacology 20040101 |
Multiple comparisons in drug efficacy studies: scientific or marketing principles? | Ethical human psychology and psychiatry 20040101 |
Topical delivery of celecoxib using microemulsion. | Acta poloniae pharmaceutica 20040101 |
Carbonic anhydrase inhibitors that directly inhibit anion transport by the human Cl-/HCO3- exchanger, AE1. | Molecular membrane biology 20040101 |
[Celecoxib and Tramadol as an alternative osteoarthrosis therapy in patients with NSAID gastropathy]. | Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology 20040101 |
Physical stability and solubility advantage from amorphous celecoxib: the role of thermodynamic quantities and molecular mobility. | Molecular pharmaceutics 20040101 |
Effect of nimesulide-a preferential COX-2 inhibitor on arterial blood pressure, compared to ketoprofen. | Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 20040101 |
Safety and efficacy of oral nonsteroidal anti-inflammatory drugs in patients with rheumatoid arthritis : a six-month randomised study. | Clinical drug investigation 20040101 |
In the beginning there was colectomy: current surgical options in familial adenomatous polyposis. | Hereditary cancer in clinical practice 20040101 |
[New prevention strategies against breast cancer and cervical carcinoma. What can you advice to your patients]. | MMW Fortschritte der Medizin 20031211 |
Synthesis and structure-activity relationship of novel, highly potent metharyl and methcycloalkyl cyclooxygenase-2 (COX-2) selective inhibitors. | Journal of medicinal chemistry 20031204 |
Targeting angiogenesis: a review of angiogenesis inhibitors in the treatment of lung cancer. | Lung cancer (Amsterdam, Netherlands) 20031201 |
Cyclooxygenase-2 (COX-2) inhibition limits abnormal COX-2 expression and progressive injury in the remnant kidney. | Kidney international 20031201 |
Cyclooxygenase 2 mediates post-inflammatory colonic secretory and barrier dysfunction. | Gut 20031201 |
Discovery of 2-phenyl-3-sulfonylphenyl-indole derivatives as a new class of selective COX-2 inhibitors. | Bioorganic & medicinal chemistry 20031201 |
[Clinical pharmacology of the selective COX-2 inhibitors]. | Der Orthopade 20031201 |
Safety of cyclooxygenase 2 inhibitors and increased leukotriene synthesis in chronic idiopathic urticaria with sensitivity to nonsteroidal anti-inflammatory drugs. | Archives of dermatology 20031201 |
Celecoxib modulates the capacity for prostaglandin E2 and interleukin-10 production in alveolar macrophages from active smokers. | Clinical cancer research : an official journal of the American Association for Cancer Research 20031201 |
Cyclooxygenase inhibition and mechanisms of colorectal cancer prevention. | Current cancer drug targets 20031201 |
Incidence of outpatient physician claims for upper gastrointestinal symptoms among new users of celecoxib, ibuprofen, and naproxen in an insured population in the United States. | The American journal of gastroenterology 20031201 |
The cyclooxygenase-2 inhibitor, celecoxib, prevents the development of mammary tumors in Her-2/neu mice. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20031201 |
Tolerability of cyclooxygenase 2 inhibitors and the advisability of oral challenge. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20031201 |
Targeting cyclooxygenase-2 in human neoplasia: rationale and promise. | Cancer cell 20031201 |
Effect of the antenatal administration of celecoxib during the second and third trimesters of pregnancy on prostaglandin, cytokine, and nitric oxide levels in rabbits. | American journal of obstetrics and gynecology 20031201 |
Response of fetal prostanoids, nitric oxide, and ductus arteriosus to the short- and long-term antenatal administration of celecoxib, a selective cyclo-oxygenase-2 inhibitor, in the pregnant rabbit. | American journal of obstetrics and gynecology 20031201 |
Cox-2 is needed but not sufficient for apoptosis induced by Cox-2 selective inhibitors in colon cancer cells. | Apoptosis : an international journal on programmed cell death 20031201 |
'Open access' generic method for continuous determination of major human CYP450 probe substrates/metabolites and its application in drug metabolism studies. | Xenobiotica; the fate of foreign compounds in biological systems 20031201 |
An observational, retrospective, cohort study of dosing patterns for rofecoxib and celecoxib in the treatment of arthritis. | Clinical therapeutics 20031201 |
Toxic epidermal necrolysis as a complication of treatment with celecoxib. | Dermatology online journal 20031201 |
Patient perception of the burden of weight gain and blood pressure increase among RA patients using celecoxib, rofecoxib, and non-specific NSAIDs. | Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20031201 |
Why don't we initiate more large simple randomized controlled trials? | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20031125 |
Celecoxib, rofecoxib, and acute temporary visual impairment. | BMJ (Clinical research ed.) 20031122 |
[Celecoxib in NSAID-induced cutaneous and respiratory adverse reactions]. | Medicina clinica 20031122 |
[Role of Helicobacter pylori in drug-induced gastrointestinal bleeding]. | Presse medicale (Paris, France : 1983) 20031122 |
Design and synthesis of novel celecoxib analogues as selective cyclooxygenase-2 (COX-2) inhibitors: replacement of the sulfonamide pharmacophore by a sulfonylazide bioisostere. | Bioorganic & medicinal chemistry 20031117 |
Tempol, an antioxidant, restores endothelium-derived hyperpolarizing factor-mediated vasodilation during hypertension. | European journal of pharmacology 20031114 |
Differential effects of selective cyclooxygenase-2 inhibitors on endothelial function in salt-induced hypertension. | Circulation 20031111 |
[Prevention of colorectal cancer: acetylsalicyclic acid and cyclo-oxygenase-2 inhibitors are only partially effective]. | Nederlands tijdschrift voor geneeskunde 20031108 |
Design, synthesis, and biological evaluation of 6-substituted-3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: a novel class of diarylheterocyclic selective cyclooxygenase-2 inhibitors. | Journal of medicinal chemistry 20031106 |
Comparison of the incidence rates of selected gastrointestinal events reported for patients prescribed celecoxib and meloxicam in general practice in England using prescription-event monitoring (PEM) data. | Rheumatology (Oxford, England) 20031101 |
Comparison of the incidence rates of thromboembolic events reported for patients prescribed celecoxib and meloxicam in general practice in England using Prescription-Event Monitoring (PEM) data. | Rheumatology (Oxford, England) 20031101 |
Effects of valeryl salicylate, a COX-1 inhibitor, on models of acute inflammation in mice. | Pharmacological research 20031101 |
Use of NSAIDs for the chemoprevention of colorectal cancer. | The Annals of pharmacotherapy 20031101 |
Arachidonic acid cascade inhibitors modulate phorbol ester-induced oxidative stress in female ICR mouse skin: differential roles of 5-lipoxygenase and cyclooxygenase-2 in leukocyte infiltration and activation. | Free radical biology & medicine 20031101 |
Drug utilization review of celecoxib in Ontario. | Rheumatology (Oxford, England) 20031101 |
Persistency of use of COX-2-specific inhibitors and non-specific non-steroidal anti-inflammatory drugs (NSAIDs) in Quebec. | Rheumatology (Oxford, England) 20031101 |
Underutilization of preventive strategies in patients receiving NSAIDs. | Rheumatology (Oxford, England) 20031101 |
Measuring dyspepsia-related health in randomized trials: the Severity of Dyspepsia Assessment (SODA) and its use in treatment with NSAIDs and COX-2-specific inhibitors. | Rheumatology (Oxford, England) 20031101 |
The burden of acute postoperative pain and the potential role of the COX-2-specific inhibitors. | Rheumatology (Oxford, England) 20031101 |
Characterization of solid-state forms of celecoxib. | European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20031101 |
Gastroprotection by coxibs: what do the Celecoxib Long-Term Arthritis Safety Study and the Vioxx Gastrointestinal Outcomes Research Trial tell us? | Rheumatic diseases clinics of North America 20031101 |
Comparing the efficacy of cyclooxygenase 2-specific inhibitors in treating osteoarthritis: appropriate trial design considerations and results of a randomized, placebo-controlled trial. | Arthritis and rheumatism 20031101 |
Comparison of changes in blood pressure measurements and antihypertensive therapy in older, hypertensive, ambulatory care patients prescribed celecoxib or rofecoxib. | Pharmacotherapy 20031101 |
Drug-induced bilateral transient myopia with the sulphonamide sulphasalazine. | Ophthalmic & physiological optics : the journal of the British College of Ophthalmic Opticians (Optometrists) 20031101 |
COX-2 inhibition and prostaglandin receptors in experimental nephritis. | European journal of clinical investigation 20031101 |
[Protective effect of selective cyclooxygenase-2 inhibitor on alcohol-induced liver injury in rats]. | Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology 20031101 |
Lithium interaction with the cyclooxygenase 2 inhibitors rofecoxib and celecoxib and other nonsteroidal anti-inflammatory drugs. | The Journal of clinical psychiatry 20031101 |
Effect of itraconazole on the pharmacokinetics of celecoxib in healthy human volunteers. | Die Pharmazie 20031101 |
Regulation of cell growth by selective COX-2 inhibitors in oral carcinoma cell lines. | Prostaglandins & other lipid mediators 20031101 |
Celecoxib has a positive effect on the overall metabolism of hyaluronan and proteoglycans in human osteoarthritic cartilage. | The Journal of rheumatology 20031101 |
Differential regulation of cyclooxygenase-2 expression by phytosphingosine derivatives, NAPS and TAPS, and its role in the NAPS or TAPS-mediated apoptosis. | The Journal of investigative dermatology 20031101 |
[Severe cutaneous drug reactions to celecoxib (Celebrex)]. | Annales de dermatologie et de venereologie 20031101 |
Lessons from early large-scale adoption of celecoxib and rofecoxib by Australian general practitioners. | The Medical journal of Australia 20031020 |
Chronic inhibition of cyclooxygenase-2 does not alter plaque composition in a mouse model of advanced unstable atherosclerosis. | Cardiovascular research 20031015 |
Inhibition of angiotensin II activity enhanced the antitumor effect of cyclooxygenase-2 inhibitors via insulin-like growth factor I receptor pathway. | Cancer research 20031015 |
Increased NF-kappaB DNA binding but not transcriptional activity during apoptosis induced by the COX-2-selective inhibitor NS-398 in colorectal carcinoma cells. | British journal of cancer 20031006 |
Neutrophil elastase stimulates human airway epithelial cells to produce PGE2 through activation of p44/42 MAPK and upregulation of cyclooxygenase-2. | American journal of physiology. Lung cellular and molecular physiology 20031001 |
Inhibition of cutaneous ultraviolet light B-mediated inflammation and tumor formation with topical celecoxib treatment. | Molecular carcinogenesis 20031001 |
Anaphylactic drug reaction to celecoxib and sulfamethoxazole: cross reactivity or coincidence? | Allergy 20031001 |
Effects of rofecoxib, celecoxib, and parecoxib on anti-IgE-induced histamine release from human skin mast cells and basophils. | Allergy 20031001 |
Safety of COX-2 inhibitors in asthma patients with aspirin hypersensitivity. | The Annals of pharmacotherapy 20031001 |
Enhancing radiotherapy with cyclooxygenase-2 enzyme inhibitors: a rational advance? | Journal of the National Cancer Institute 20031001 |
Celecoxib modulates the expression of cyclooxygenase-2, ki67, apoptosis-related marker, and microvessel density in human cervical cancer: a pilot study. | Clinical cancer research : an official journal of the American Association for Cancer Research 20031001 |
[Effect of selective cyclooxygenase-2 inhibitor celebrex on expression of vascular endothelial growth factor (VEGF) in pancreatic carcinoma]. | Ai zheng = Aizheng = Chinese journal of cancer 20031001 |
Cyclooxygenase-2 inhibition decreases primary and metastatic tumor burden in a murine model of orthotopic lung adenocarcinoma. | The Journal of thoracic and cardiovascular surgery 20031001 |
Chemotherapeutic and biologic agents as radiosensitizers in rectal cancer. | Seminars in radiation oncology 20031001 |
Introduction to monitoring. What is what you prescribed actually doing? | Australian family physician 20031001 |
Persistence with COX-2 inhibitors in managed care: an analysis of claims data. | Managed care interface 20031001 |
Cyclooxygenase-2 and gastric carcinogenesis. | APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 20031001 |
Histamine mediates the pro-inflammatory effect of latex of Calotropis procera in rats. | Mediators of inflammation 20031001 |
[Cyclooxygenases in the spinal cord and the relationship with pain]. | Sheng li ke xue jin zhan [Progress in physiology] 20031001 |
[New studies of COX-inhibitors, yet issues remain]. | Lakartidningen 20030918 |
Synthesis and cyclooxygenase-2 inhibiting property of 1,5-diarylpyrazoles with substituted benzenesulfonamide moiety as pharmacophore: Preparation of sodium salt for injectable formulation. | Journal of medicinal chemistry 20030911 |
Carcinogenesis and cyclooxygenase: the potential role of COX-2 inhibition in upper aerodigestive tract cancer. | Oral oncology 20030901 |
Cyclo-oxygenase-2 mediated prostaglandin release regulates blood flow in connective tissue during mechanical loading in humans. | The Journal of physiology 20030901 |
Short- and long-term COX-2 inhibition reverses endothelial dysfunction in patients with hypertension. | Hypertension (Dallas, Tex. : 1979) 20030901 |
Apoptosis induction and enhancement of cytotoxicity of anticancer drugs by celecoxib, a selective cyclooxygenase-2 inhibitor, in human head and neck carcinoma cell lines. | International journal of oncology 20030901 |
Channelling bias and the incidence of gastrointestinal haemorrhage in users of meloxicam, coxibs, and older, non-specific non-steroidal anti-inflammatory drugs. | Gut 20030901 |
Adverse Drug Events Involving COX-2 Inhibitors. | The Annals of pharmacotherapy 20030901 |
Cyclooxygenase-2 promotes hepatocellular carcinoma cell growth through Akt activation: evidence for Akt inhibition in celecoxib-induced apoptosis. | Hepatology (Baltimore, Md.) 20030901 |
NSAIDs and Alzheimer's disease: how far to generalise from trials? | The Lancet. Neurology 20030901 |
Chemotherapeutic efficacy of topical celecoxib in a murine model of ultraviolet light B-induced skin cancer. | Molecular carcinogenesis 20030901 |
Comparative protection against rat intestinal reperfusion injury by a new inhibitor of sPLA2, COX-1 and COX-2 selective inhibitors, and an LTC4 receptor antagonist. | British journal of pharmacology 20030901 |
Effect of combined cyclooxygenase-2 and matrix metalloproteinase inhibition on human sarcoma xenografts. | Journal of pediatric hematology/oncology 20030901 |
4-substituted 1,5-diarylpyrazole, analogues of celecoxib: synthesis and preliminary evaluation of biological properties. | Farmaco (Societa chimica italiana : 1989) 20030901 |
Differential effects of aspirin and misoprostol on 15-hydroxyeicosatetraenoic acid generation by leukocytes from aspirin-sensitive asthmatic patients. | The Journal of allergy and clinical immunology 20030901 |
Inhibition of cyclooxygenase (COX) enzymes by compounds from Daucus carota L. Seeds. | Phytotherapy research : PTR 20030901 |
Simple method for the determination of rosiglitazone in human plasma using a commercially available internal standard. | Biomedical chromatography : BMC 20030901 |
Inhibition of COX-2 in colon cancer cell lines by celecoxib increases the nuclear localization of active p53. | Cancer research 20030901 |
Irinotecan in esophageal cancer. | Oncology (Williston Park, N.Y.) 20030901 |
Solubility enhancement of Cox-2 inhibitors using various solvent systems. | AAPS PharmSciTech 20030901 |
Celecoxib anti-aromatase neoadjuvant (CAAN) trial for locally advanced breast cancer: preliminary report. | The Journal of steroid biochemistry and molecular biology 20030901 |
Breast cancer prevention--clinical trials strategies involving aromatase inhibitors. | The Journal of steroid biochemistry and molecular biology 20030901 |
[Lower gastrointestinal hemorrhage associated with celecoxib]. | Anales de medicina interna (Madrid, Spain : 1984) 20030901 |
Cardiovascular thrombotic events in arthritis trials of the cyclooxygenase-2 inhibitor celecoxib. | The American journal of cardiology 20030815 |
Suppression of N-methyl-N-nitrosourea/testosterone-induced rat prostate cancer growth by celecoxib: effects on cyclooxygenase-2, cell cycle regulation, and apoptosis mechanism(s). | Clinical cancer research : an official journal of the American Association for Cancer Research 20030815 |
Functional and biochemical evaluation of platelet aspirin resistance after coronary artery bypass surgery. | Circulation 20030805 |
Celecoxib activates a novel mitochondrial apoptosis signaling pathway. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030801 |
A validated spectrofluorometric method for the determination of celecoxib in capsules. | Analytical and bioanalytical chemistry 20030801 |
Angiogenesis inhibitors under study for the treatment of lung cancer. | Lung cancer (Amsterdam, Netherlands) 20030801 |
Targeted therapies for stage III non-small cell lung cancer: integration in the combined modality setting. | Lung cancer (Amsterdam, Netherlands) 20030801 |
Evidence that 5-lipoxygenase and acetylated cyclooxygenase 2-derived eicosanoids regulate leukocyte-endothelial adherence in response to aspirin. | British journal of pharmacology 20030801 |
Celecoxib inhibits metabolism of cytochrome P450 2D6 substrate metoprolol in humans. | Clinical pharmacology and therapeutics 20030801 |
The cyclooxygenase-2-selective inhibitors rofecoxib and celecoxib prevent colorectal neoplasia occurrence and recurrence. | Gastroenterology 20030801 |
Influence of CYP2C9 genetic polymorphisms on pharmacokinetics of celecoxib and its metabolites. | Pharmacogenetics 20030801 |
COX-2 inhibitors and cancer therapeutics: potential roles for inhibitors of COX-2 in combination with cytotoxic therapy: reports from a symposium held in conjunction with the Radiation Therapy Oncology Group June 2001 Meeting. | American journal of clinical oncology 20030801 |
Initial experience combining cyclooxygenase-2 inhibition with chemoradiation for locally advanced pancreatic cancer. | American journal of clinical oncology 20030801 |
Combination of a COX-2 inhibitor with radiotherapy or radiochemotherapy in the treatment of thoracic cancer. | American journal of clinical oncology 20030801 |
Combination of radiation and celebrex (celecoxib) reduce mammary and lung tumor growth. | American journal of clinical oncology 20030801 |
COX-2 inhibitors as radiation sensitizers for upper GI tract cancers: esophagus, stomach, and pancreas. | American journal of clinical oncology 20030801 |
Celecoxib reduces skin damage after radiation: selective reduction of chemokine and receptor mRNA expression in irradiated skin but not in irradiated mammary tumor. | American journal of clinical oncology 20030801 |
Preparation and characterization of glassy celecoxib. | Drug development and industrial pharmacy 20030801 |
[Celecoxib as well as Diclofenac in Combination with Omeprazole can Prevent the Recurrence of NSAIDs-Induced Gastrointestinal Bleeding]. | Zeitschrift fur Gastroenterologie 20030801 |
The cyclooxygenase 2-specific nonsteroidal anti-inflammatory drugs celecoxib and nimesulide inhibit androgen receptor activity via induction of c-Jun in prostate cancer cells. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20030801 |
Effect of celecoxib and dexamethasone on postoperative pain after lumbar disc surgery. | Neurosurgery 20030801 |
[Selective COX-2 inhibition improves endothelial function in coronary artery disease]. | Zeitschrift fur Rheumatologie 20030801 |
In vivo effects of meloxicam, celecoxib, and ibuprofen on free radical metabolism in human erythrocytes. | Drug and chemical toxicology 20030801 |
COX-2 inhibitors in oncology. | Seminars in oncology 20030801 |
Current and ongoing trials with irinotecan in the United States. | Seminars in oncology 20030801 |
Indomethacin and celecoxib improve tendon healing in rats. | Acta orthopaedica Scandinavica 20030801 |
Selective inhibition of cyclooxygenase 2 induces p27kip1 and skp2 in oral squamous cell carcinoma. | The Journal of otolaryngology 20030801 |
[Clinical pharmacology of selective inhibitors of cyclooxygenase-2]. | Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale 20030801 |
Synthesis and structure-activity relationship of a new series of COX-2 selective inhibitors: 1,5-diarylimidazoles. | Journal of medicinal chemistry 20030731 |
Topical inhibition of oral carcinoma cell with polymer delivered celecoxib. | Cancer letters 20030730 |
Adsorptive stripping voltammetric determination of the anti-inflammatory drug celecoxib in pharmaceutical formulation and human serum. | Talanta 20030727 |
Non-steroidal anti-inflammatory drugs and molecular carcinogenesis of colorectal carcinomas. | Lancet (London, England) 20030719 |
Celecoxib, a selective cyclo-oxygenase-2 inhibitor, enhances the response to preoperative paclitaxel and carboplatin in early-stage non-small-cell lung cancer. | Journal of clinical oncology : official journal of the American Society of Clinical Oncology 20030715 |
Chronic spinal pain: a randomized clinical trial comparing medication, acupuncture, and spinal manipulation. | Spine 20030715 |
Economic analysis of celecoxib versus diclofenac plus omeprazole for the treatment of arthritis in patients at risk of ulcer disease. | Alimentary pharmacology & therapeutics 20030715 |
Inhibition of cancer cell proliferation and prostaglandin E2 synthesis by Scutellaria baicalensis. | Cancer research 20030715 |
6-Alkyl, alkoxy, or alkylthio-substituted 3-(4-methanesulfonylphenyl)-4-phenylpyran-2-ones: a novel class of diarylheterocyclic selective cyclooxygenase-2 inhibitors. | Bioorganic & medicinal chemistry letters 20030707 |
Pain management in patients with osteoarthritis. | JAMA 20030702 |
Effects of nonsteroidal anti-inflammatory drugs on prostacyclin and thromboxane in the kidney. | Pharmacology 20030701 |
Celecoxib associated esophagitis: review of gastrointestinal side effects from cox-2 inhibitors. | Journal of clinical gastroenterology 20030701 |
Celecoxib-induced fixed drug eruption. | Clinical and experimental dermatology 20030701 |
Celecoxib-induced lupus-like syndrome. | Rheumatology (Oxford, England) 20030701 |
Synthesis of novel 1,3,4-trisubstituted pyrazole derivatives and their evaluation as antitumor and antiangiogenic agents. | Chemical & pharmaceutical bulletin 20030701 |
Tissue-specific plantar fascia-stretching exercise enhances outcomes in patients with chronic heel pain. A prospective, randomized study. | The Journal of bone and joint surgery. American volume 20030701 |
Irinotecan, cisplatin/carboplatin, and COX-2 inhibition in small-cell lung cancer. | Oncology (Williston Park, N.Y.) 20030701 |
Interaction of rofecoxib and celecoxib with warfarin. | American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists 20030701 |
Celecoxib and rofecoxib potentiate chronic colitis and premalignant changes in interleukin 10 knockout mice. | Inflammatory bowel diseases 20030701 |
[The effects of selective cyclooxygenase-2 inhibitors on the growth of gastric adenocarcinoma]. | Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 20030701 |
Quadriparesis in a young female suffering from rheumatoid arthritis. | The Journal of the Association of Physicians of India 20030701 |
The cost effectiveness of rofecoxib and celecoxib in patients with osteoarthritis or rheumatoid arthritis. | Arthritis and rheumatism 20030615 |
Celecoxib inhibits proliferation and induces apoptosis via prostaglandin E2 pathway in human cholangiocarcinoma cell lines. | World journal of gastroenterology 20030615 |
Cyclooxygenase-2 expression and effect of celecoxib in gastric adenomas of trefoil factor 1-deficient mice. | Cancer research 20030615 |
Mechanisms of angiotensin-converting enzyme inhibitor induced thrombolysis in Wistar rats. | Thrombosis research 20030615 |
Celecoxib versus diclofenac and omeprazole to prevent recurrent ulcer bleeding. | The New England journal of medicine 20030612 |
Celecoxib versus diclofenac and omeprazole to prevent recurrent ulcer bleeding. | The New England journal of medicine 20030612 |
Celecoxib versus diclofenac and omeprazole to prevent recurrent ulcer bleeding. | The New England journal of medicine 20030612 |
Risk of cancer in a large cohort of nonaspirin NSAID users: a population-based study. | British journal of cancer 20030602 |
Bioactivation of cyclophosphamide: the role of polymorphic CYP2C enzymes. | European journal of clinical pharmacology 20030601 |
Relative contribution of acetylated cyclo-oxygenase (COX)-2 and 5-lipooxygenase (LOX) in regulating gastric mucosal integrity and adaptation to aspirin. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030601 |
The efficacy of celecoxib premedication on postoperative pain and recovery times after ambulatory surgery: a dose-ranging study. | Anesthesia and analgesia 20030601 |
Selective celecoxib-associated anaphylactoid reaction. | The Journal of allergy and clinical immunology 20030601 |
COX-2: an in vivo evidence of its participation in heat stress-induced myocardial preconditioning. | Cardiovascular research 20030601 |
Preoperative oral celecoxib versus preoperative oral rofecoxib for pain relief after thyroid surgery. | European journal of anaesthesiology 20030601 |
Rofecoxib in rheumatoid arthritis: new indication. No better that other NSAIDS. | Prescrire international 20030601 |
The cost-effectiveness of cyclooxygenase-2 selective inhibitors in the management of chronic arthritis. | Annals of internal medicine 20030520 |
Summaries for patients. The cost-effectiveness of cyclooxygenase-2 inhibitors for treating chronic arthritis. | Annals of internal medicine 20030520 |
Blood pressure control and rates of edema following the administration of the cyclooxygenase-2 specific inhibitors celecoxib versus rofecoxib in patients with systemic hypertension and osteoarthritis. | The American journal of cardiology 20030515 |
Cooperative effects of matrix metalloproteinase and cyclooxygenase-2 inhibition on intestinal adenoma reduction. | British journal of cancer 20030506 |
Age-related difference in susceptibility of Apc(Min/+) mice towards the chemopreventive efficacy of dietary aspirin and curcumin. | British journal of cancer 20030506 |
PAR1-dependent and independent increases in COX-2 and PGE2 in human colonic myofibroblasts stimulated by thrombin. | American journal of physiology. Cell physiology 20030501 |
Comment: acute cholestatic hepatitis associated with celecoxib. | The Annals of pharmacotherapy 20030501 |
Does the release of arachidonic acid from cells play a role in cancer chemoprevention? | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20030501 |
Hyperalgesia induced by Asp49 and Lys49 phospholipases A2 from Bothrops asper snake venom: pharmacological mediation and molecular determinants. | Toxicon : official journal of the International Society on Toxinology 20030501 |
Biochemical and clinical evidence that aspirin-intolerant asthmatic subjects tolerate the cyclooxygenase 2-selective analgetic drug celecoxib. | The Journal of allergy and clinical immunology 20030501 |
Point: From animal models to prevention of colon cancer. Systematic review of chemoprevention in min mice and choice of the model system. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20030501 |
Possible international normalized ratio elevation associated with celecoxib and warfarin in an elderly psychiatric patient. | Journal of the American Geriatrics Society 20030501 |
Celecoxib and difluoromethylornithine in combination have strong therapeutic activity against UV-induced skin tumors in mice. | Carcinogenesis 20030501 |
Motion--Cyclo-oxygenase-2 selective nonsteroidal anti-inflammatory drugs are as safe as placebo for the stomach: arguments against the motion. | Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20030501 |
Motion--Cyclo-oxygenase-2 selective nonsteroidal anti-inflammatory drugs are as safe as placebo for the stomach: arguments for the motion. | Canadian journal of gastroenterology = Journal canadien de gastroenterologie 20030501 |
Effect of vehicles and penetration enhancers on the in vitro percutaneous absorption of celecoxib through human skin. | Die Pharmazie 20030501 |
Improvement of radiotherapy or chemoradiotherapy by targeting COX-2 enzyme. | Oncology (Williston Park, N.Y.) 20030501 |
[Adverse effect-free analgesia. New COX-2 inhibitor is even more selective]. | MMW Fortschritte der Medizin 20030501 |
[Adverse cutaneous reaction to celecoxib: 6 cases]. | Annales de dermatologie et de venereologie 20030501 |
[Hypersensitivity to celecoxib]. | Annales de medecine interne 20030501 |
Aspirin and other cyclooxygenase inhibitors: new therapeutic insights. | Seminars in vascular medicine 20030501 |
Drugs in the news: an analysis of Canadian newspaper coverage of new prescription drugs. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20030429 |
[The selective cyclooxygenase-2 inhibitor celecoxib is a safe alternative in patients with pseudo-allergic reactions to nonsteroidal anti-inflammatory drugs]. | Medizinische Klinik (Munich, Germany : 1983) 20030425 |
Oesophageal squamous cell neoplasia in head and neck cancer patients: upregulation of COX-2 during carcinogenesis. | British journal of cancer 20030422 |
Intrahippocampal infusion of a cyclooxygenase-2 inhibitor attenuates memory acquisition in rats. | Brain research 20030411 |
Theoretical studies on the inhibition mechanism of cyclooxygenase-2. Is there a unique recognition site? | Journal of medicinal chemistry 20030410 |
Do altering in ornithine decarboxylase activity and gene expression contribute to antiproliferative properties of COX inhibitors? | British journal of cancer 20030407 |
Synthesis and biological evaluation of substituted 2-sulfonyl-phenyl-3-phenyl-indoles: a new series of selective COX-2 inhibitors. | Bioorganic & medicinal chemistry 20030403 |
Toward safer methodologies for the synthesis of polyheterocyclic systems: intramolecular arylation of arenes under Mizoroki-Heck reaction conditions. | Organic letters 20030403 |
The anti-inflammatory effects of the phosphodiesterase inhibitor pentoxifylline in the rat. | Pharmacological research 20030401 |
Characterization of celecoxib and valdecoxib binding to cyclooxygenase. | Molecular pharmacology 20030401 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery. | Anesthesia and analgesia 20030401 |
Effects of selective COX-2 inhibitors on the gastric permeability of sucrose: a controlled study with placebo and ibuprofen. | European journal of gastroenterology & hepatology 20030401 |
No success with the SUCCESS trial. | The American journal of cardiology 20030401 |
Prevention and treatment of reactions to NSAIDs. | Clinical reviews in allergy & immunology 20030401 |
A life-threatening interaction between lithium and celecoxib. | British journal of clinical pharmacology 20030401 |
Chemoprevention of colorectal cancer: slow, steady progress. | Cleveland Clinic journal of medicine 20030401 |
Comparison of the efficacy and tolerability of dexibuprofen and celecoxib in the treatment of osteoarthritis of the hip. | International journal of clinical pharmacology and therapeutics 20030401 |
Relative efficacy of selective COX-2 inhibitors compared with over-the-counter ibuprofen. | International journal of clinical practice. Supplement 20030401 |
Risk factors associated with the development of gastroduodenal ulcers due to the use of NSAIDs. | International journal of clinical practice. Supplement 20030401 |
A side effect of COX-2 inhibitors. | Harvard health letter 20030401 |
The cox-2-specific inhibitor celecoxib inhibits adenylyl cyclase. | Inflammation 20030401 |
[Coxibs: highly selective cyclooxygenase-2 inhibitors. Part I. Clinical efficacy]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20030401 |
[Coxibs: highly selective cyclooxygenase-2 inhibitors. Part II. Side effects]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20030401 |
Role of cyclooxygenase 2 in protein kinase C beta II-mediated colon carcinogenesis. | The Journal of biological chemistry 20030328 |
Cyclooxygenase inhibitory and antioxidant compounds from crabapple fruits. | Journal of agricultural and food chemistry 20030326 |
3,4-Diaryl-5-hydroxyfuranones: highly selective inhibitors of cyclooxygenase-2 with aqueous solubility. | Bioorganic & medicinal chemistry letters 20030324 |
Nonsteroidal anti-inflammatory drugs in colorectal cancer: from prevention to therapy. | British journal of cancer 20030324 |
Non-steroidal anti-inflammatory drug sodium salicylate, but not diclofenac or celecoxib, protects against 1-methyl-4-phenyl pyridinium-induced dopaminergic neurotoxicity in rats. | Brain research 20030321 |
[The future of peptic ulcer disease without Helicobacter]. | Praxis 20030319 |
Intellectual property. Judge turns Rochester's golden patent into lead. | Science (New York, N.Y.) 20030314 |
[Selective Cox-2 inhibitor in osteoarthritis and rheumatoid arthritis. No increased risk for the heart]. | MMW Fortschritte der Medizin 20030313 |
[Gastrointestinal complications caused by NSAIDs. Over 60% of arthrosis patients are endangered]. | MMW Fortschritte der Medizin 20030306 |
Cyclooxygenase-2 inhibitors: is there an association with coronary or renal events? | Current atherosclerosis reports 20030301 |
Effect of cyclooxygenase-2 inhibitors on blood pressure. | The Annals of pharmacotherapy 20030301 |
Anti-inflammatory drugs may put on the pressure. | Harvard heart letter : from Harvard Medical School 20030301 |
Celecoxib acts in a cyclooxygenase-2-independent manner and in synergy with emodin to suppress rat cholangiocarcinoma growth in vitro through a mechanism involving enhanced Akt inactivation and increased activation of caspases-9 and -3. | Molecular cancer therapeutics 20030301 |
Toxic epidermal necrolysis due to administration of celecoxib (Celebrex). | Southern medical journal 20030301 |
Selective COX-2 inhibitors as chemopreventive and therapeutic agents. | Drugs of today (Barcelona, Spain : 1998) 20030301 |
Anticonvulsant action of celecoxib (alone and in combination with sub-threshold dose of phenytoin) in electroshock induced convulsion. | Methods and findings in experimental and clinical pharmacology 20030301 |
Valdecoxib: a review. | Clinical therapeutics 20030301 |
Effect of selective cyclooxygenase 2 inhibitors and naproxen on short-term risk of acute myocardial infarction in the elderly. | Archives of internal medicine 20030224 |
2,3-Diarylbenzopyran derivatives as a novel class of selective cyclooxygenase-2 inhibitors. | Bioorganic & medicinal chemistry letters 20030210 |
Systematic review of celecoxib for osteoarthritis and rheumatoid arthritis. Problems compromise review's validity. | BMJ (Clinical research ed.) 20030208 |
Systematic review of celecoxib for osteoarthritis and rheumatoid arthritis. Celecoxib's relative gastrointestinal safety is overstated. | BMJ (Clinical research ed.) 20030208 |
Effects of nabumetone, celecoxib, and ibuprofen on blood pressure control in hypertensive patients on angiotensin converting enzyme inhibitors. | American journal of hypertension 20030201 |
Cyclooxygenase 2: a molecular target for cancer prevention and treatment. | Trends in pharmacological sciences 20030201 |
Bad medicine. Why data from drug companies may be hard to swallow. | Scientific American 20030201 |
Review article: NSAIDs, gastroprotection and cyclo-oxygenase-II-selective inhibitors. | Alimentary pharmacology & therapeutics 20030201 |
Up-regulation of tumor interleukin-8 expression by infiltrating macrophages: its correlation with tumor angiogenesis and patient survival in non-small cell lung cancer. | Clinical cancer research : an official journal of the American Association for Cancer Research 20030201 |
Role of cyclooxygenases COX-1 and COX-2 in modulating adipogenesis in 3T3-L1 cells. | Journal of lipid research 20030201 |
Comparing celecoxib with traditional nonsteroidal anti-inflammatory drugs. | The Journal of family practice 20030201 |
Selective cyclooxygenase-2 inhibition does not affect the healing of cutaneous full-thickness incisional wounds in SKH-1 mice. | The British journal of dermatology 20030201 |
Membranous glomerulopathy and acute interstitial nephritis following treatment with celecoxib. | Clinical nephrology 20030201 |
Role of gastric mucosal and gastric juice cytokine concentrations in development of bisphosphonate damage to gastric mucosa. | Digestive diseases and sciences 20030201 |
A model analysis of costs of blood pressure destabilization and edema associated with rofecoxib and celecoxib among older patients with osteoarthritis and hypertension in a Medicare Choice population. | Clinical therapeutics 20030201 |
Acidic nonsteroidal anti-inflammatory drugs inhibit rat brain fatty acid amide hydrolase in a pH-dependent manner. | Journal of enzyme inhibition and medicinal chemistry 20030201 |
[When the cardiac patient with arthritis needs aspirin and NSAID: how to protect the stomach?]. | MMW Fortschritte der Medizin 20030130 |
Selective COX-2 inhibition improves endothelial function in coronary artery disease. | Circulation 20030128 |
[Rapid, strong and long-term effectiveness. Coxib also effective in toothache]. | MMW Fortschritte der Medizin 20030116 |
Modulation of cyclooxygenase-2 on glycine- and glutamate-induced ion currents in rat periaqueductal gray neurons. | Brain research bulletin 20030115 |
Proliferative activity of bile from congenital choledochal cyst patients. | World journal of gastroenterology 20030115 |
Celecoxib-related renal papillary necrosis. | Archives of internal medicine 20030113 |
Simultaneous determination of celecoxib, hydroxycelecoxib, and carboxycelecoxib in human plasma using gradient reversed-phase liquid chromatography with ultraviolet absorbance detection. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030105 |
Celecoxib, a selective cyclooxygenase-2 inhibitor, inhibits retinal vascular endothelial growth factor expression and vascular leakage in a streptozotocin-induced diabetic rat model. | European journal of pharmacology 20030105 |
Why aren't lower, effective, OTC doses available earlier by prescription? | The Annals of pharmacotherapy 20030101 |
A randomized, clinical trial comparing oral celecoxib 200 mg, celecoxib 400 mg, and ibuprofen 600 mg for acute pain. | Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 20030101 |
Recent progress in ankylosing spondylitis treatment. | Expert opinion on pharmacotherapy 20030101 |
American pain society pain questionnaire and other pain measures in the assessment of osteoarthritis pain: a pooled analysis of three celecoxib pivotal studies. | American journal of therapeutics 20030101 |
Celecoxib in human milk: a case report. | Pharmacotherapy 20030101 |
Cancer chemoprevention drug targets. | Current drug targets 20030101 |
Role of endogenous glucocorticoids in hyperalgesia and edema in old arthritic rats. | Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas 20030101 |
Drug-induced hypertension. | Journal of clinical hypertension (Greenwich, Conn.) 20030101 |
Lipoxygenase and cyclooxygenase metabolism: new insights in treatment and chemoprevention of pancreatic cancer. | Molecular cancer 20030101 |
Safety of celecoxib in individuals allergic to sulfonamide: a pilot study. | Drug safety 20030101 |
Reduction of scar formation in full-thickness wounds with topical celecoxib treatment. | Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 20030101 |
Influence of age and cytochrome P450 2C9 genotype on the steady-state disposition of diclofenac and celecoxib. | Clinical pharmacokinetics 20030101 |
Cancer 'photo-chemoprevention' with pulsed dye laser and celecoxib. | Lasers in surgery and medicine 20030101 |
[Cost-effectiveness analysis of the use of celecoxib for the treatment of osteoarthritis]. | Gaceta sanitaria 20030101 |
Antenatal administration of celecoxib, a selective cyclooxygenase (COX)-2 inhibitor, appears to improve placental perfusion in the pregnant rabbit. | Prostaglandins & other lipid mediators 20030101 |
COX-2 selective non-steroidal anti-inflammatory drugs and cardiovascular disease. | Pharmacoepidemiology and drug safety 20030101 |
Synthesis of 4-(5-iodo-3-methylpyrazolyl) phenylsulfonamide and its elaboration to a COX II inhibitor library by solution-phase suzuki coupling using Pd/C as a solid-supported catalyst. | Journal of combinatorial chemistry 20030101 |
Selective cyclooxygenase-2 inhibition upregulates renal cortical alpha V integrin expression. | Nephron. Experimental nephrology 20030101 |
Cyclooxygenase-2: from arthritis treatment to new indications for the prevention and treatment of cancer. | Clinical journal of oncology nursing 20030101 |
The impact of nonsteroidal anti-inflammatory drugs on blood pressure, with an emphasis on newer agents. | Clinical therapeutics 20030101 |
The prevalence of cardiorenal risk factors in patients prescribed nonsteroidal anti-inflammatory drugs: data from managed care. | Clinical therapeutics 20030101 |
The cost-effectiveness of acetaminophen, NSAIDs, and selective COX-2 inhibitors in the treatment of symptomatic knee osteoarthritis. | Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research 20030101 |
Statins stimulate arachidonic acid release and prostaglandin I2 production in rat liver cells. | Lipids in health and disease 20030101 |
[Pharmacology of cyclooxygenase 2 inhibition]. | Wiener medizinische Wochenschrift (1946) 20030101 |
[Cyclooxygenase 2 selective antirheumatic analgesics]. | Wiener medizinische Wochenschrift (1946) 20030101 |
Selective COX-2 inhibitors: a health economic perspective. | Wiener medizinische Wochenschrift (1946) 20030101 |
Studies on the applicability of tamarind kernel powder as a carrier in the dissolution enhancement of poorly water soluble drug, celecoxib. | Bollettino chimico farmaceutico 20030101 |
Cox-2: Where are we in 2003? - The role of cyclooxygenase-2 in bone repair. | Arthritis research & therapy 20030101 |
Cox-2: where are we in 2003? - Cardiovascular risk and Cox-2 inhibitors. | Arthritis research & therapy 20030101 |
COX-2: Where are we in 2003? - Specific cyclooxygenase-2 inhibitors and aspirin-exacerbated respiratory disease. | Arthritis research & therapy 20030101 |
COX-2: Where are we in 2003? - Be strong and resolute: continue to use COX-2 selective inhibitors at recommended dosages in appropriate patients. | Arthritis research & therapy 20030101 |
COX-2: where are we in 2003?--distinction from NSAIDs becoming blurred. | Arthritis research & therapy 20030101 |
Medication errors caused by confusion of drug names. | Drug safety 20030101 |
Evaluation of cyclooxygenase 2 inhibitor use in patients admitted to a large teaching hospital. | Internal medicine journal 20030101 |
Celecoxib is as efficacious as naproxen in the management of acute shoulder pain. | The Journal of international medical research 20030101 |
Therapeutic potential of selective cyclooxygenase-2 inhibitors in the management of tumor angiogenesis. | Progress in experimental tumor research 20030101 |
Single dose oral celecoxib for postoperative pain. | The Cochrane database of systematic reviews 20030101 |
Irinotecan in metastatic colorectal cancer: dose intensification and combination with new agents, including biological response modifiers. | Annals of oncology : official journal of the European Society for Medical Oncology 20030101 |
Intolerance reactions due to the selective cyclooxygenase type II inhibitors rofecoxib and celecoxib. Results of oral provocation tests in patients with NSAID hypersensitivity. | Acta dermato-venereologica 20030101 |
Celecoxib was as effective as diclofenac plus omeprazole in reducing recurrent ulcer bleeding in arthritis. | ACP journal club 20030101 |
[Interactions of nonsteroid anti-inflammatory drugs with inhibitors of angiotensin-converting enzyme in patients with rheumatic diseases (a review)]. | Terapevticheskii arkhiv 20030101 |
Prenatal effects of DuP-697-the irreversible, highly selective cyclooxygenase-2 inhibitor. | Reproductive toxicology (Elmsford, N.Y.) 20030101 |
[Effectiveness and tolerability of celecoxib in outpatient department practice]. | La Clinica terapeutica 20030101 |
[COX-2 inhibitors: a new treatment in rheumatic diseases]. | La Clinica terapeutica 20030101 |
The influence of a cyclooxygenase-1 inhibitor on injured and uninjured ligaments in the rat. | The American journal of sports medicine 20030101 |
Scratch-patch and patch testing in drug allergy--an assessment of specificity. | Journal of investigational allergology & clinical immunology 20030101 |
Celecoxib, a highly selective COX-2 inhibitor, is safe in aspirin-induced asthma patients. | Journal of investigational allergology & clinical immunology 20030101 |
Inhibition of proliferation of human cancer cells and cyclooxygenase enzymes by anthocyanidins and catechins. | Nutrition and cancer 20030101 |
Effects of selective cyclooxygenase inhibitors on ischemia/reperfusion-induced hepatic microcirculatory dysfunction in mice. | European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes 20030101 |
Current chemotherapy for glioblastoma. | Cancer journal (Sudbury, Mass.) 20030101 |
[Possible problems of lack of objectivity, transparency, duplicate publication and authorship in the cost-effectiveness analysis of celecoxib]. | Gaceta sanitaria 20030101 |
A retrospective review of the effect of COX-2 inhibitors on blood pressure change. | American journal of therapeutics 20030101 |
Improved control of osteoarthritis pain and self-reported health status in non-responders to celecoxib switched to rofecoxib: results of PAVIA, an open-label post-marketing survey in Spain. | Current medical research and opinion 20030101 |
Tamoxifen stimulates arachidonic acid release from rat liver cells by an estrogen receptor-independent, non-genomic mechanism. | BMC cancer 20030101 |
[Aromatase inhibitors--theoretical concept and present experiences in the treatment of endometriosis]. | Zentralblatt fur Gynakologie 20030101 |
A randomised, double-blind, clinical trial comparing the efficacy of nimesulide, celecoxib and rofecoxib in osteoarthritis of the knee. | Drugs 20030101 |
Chemoprevention strategies using NSAIDs and COX-2 inhibitors. | Cancer biology & therapy 20030101 |
Gastroduodenal safety of cyclooxygenase-2 inhibitors. | Current pharmaceutical design 20030101 |
COX-2 inhibition, H. pylori infection and the risk of gastrointestinal complications. | Current pharmaceutical design 20030101 |
COX-2 specific inhibitors in NSAID-intolerant patients. | International journal of immunopathology and pharmacology 20030101 |
Clinical pharmacology of selective COX-2 inhibitors. | International journal of immunopathology and pharmacology 20030101 |
Effect of nimesulide, rofecoxib and celecoxib on gastric tissue glutathione level in rats with indomethacin-induced gastric ulcerations. | Polish journal of pharmacology 20030101 |
Balancing gastroprotection and cardioprotection with selective cyclo-oxygenase-2 inhibitors: clinical implications. | Drug safety 20030101 |
Prostaglandin levels in seminal plasma and sperm extracts of the domestic turkey, and the effects of cyclooxygenase inhibitors on sperm mobility. | Reproductive biology and endocrinology : RB&E 20030101 |
Case report: multiple physicians, polypharmacy, and patient counseling. | Journal of the American Pharmacists Association : JAPhA 20030101 |
Chemoprevention for Barrett's esophagus trial. Design and outcome measures. | Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20030101 |
Effect of cyclooxygenase-2 (COX-2) inhibitors on prostate cancer cell proliferation. | Anticancer research 20030101 |
Effect of cyclooxygenase and NO synthase inhibitors administered centrally on antinociceptive action of acetaminophen (Part II). | Polish journal of pharmacology 20030101 |
Influence of rifampicin pretreatment on the pharmacokinetics of celecoxib in healthy male volunteers. | Drug metabolism and drug interactions 20030101 |
Fructooligosaccharide associated with celecoxib reduces the number of aberrant crypt foci in the colon of rats. | Reproduction, nutrition, development 20030101 |
Target definition and contouring in carcinoma of the lung and esophagus. | Rays 20030101 |
Assessment of the safety of selective cyclo-oxygenase-2 inhibitors: where are we in 2003? | Inflammopharmacology 20030101 |
Dexibuprofen: pharmacology, therapeutic uses and safety. | Inflammopharmacology 20030101 |
Celecoxib to decrease urinary retention associated with prostate brachytherapy. | Brachytherapy 20030101 |
Utilisation Pattern of Nonspecific Nonsteroidal Anti-Inflammatory Drugs and COX-2 Inhibitors in a Local Health Service Unit in Northeast Italy. | Clinical drug investigation 20030101 |
Celecoxib versus diclofenac and omeprazole in reducing the risk of recurrent ulcer bleeding in patients with arthritis. | The New England journal of medicine 20021226 |
NSAIDs, Helicobacter pylori, and Pandora's Box. | The New England journal of medicine 20021226 |
Insulin-like growth factor-I antagonizes the antiproliferative effects of cyclooxygenase-2 inhibitors on BxPC-3 pancreatic cancer cells. | Cancer research 20021215 |
Using cyclooxygenase-2 inhibitors as molecular platforms to develop a new class of apoptosis-inducing agents. | Journal of the National Cancer Institute 20021204 |
Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS. | Annals of neurology 20021201 |
Acute cholestatic hepatitis associated with celecoxib. | The Annals of pharmacotherapy 20021201 |
Arthritis treatment in Hong Kong--cost analysis of celecoxib versus conventional NSAIDS, with or without gastroprotective agents. | Alimentary pharmacology & therapeutics 20021201 |
Disease modifying and anti-nociceptive effects of the bisphosphonate, zoledronic acid in a model of bone cancer pain. | Pain 20021201 |
Nuclear receptor agonists stimulate release of arachidonic acid from rat liver cells. | Prostaglandins, leukotrienes, and essential fatty acids 20021201 |
Allergic vasculitis associated with celecoxib. | Rheumatology (Oxford, England) 20021201 |
Severe ulcers on celecoxib. | Prescrire international 20021201 |
Celecoxib and the CLASS trial: data massaging by industry. | Prescrire international 20021201 |
Induction of apoptosis in rheumatoid synovial fibroblasts by celecoxib, but not by other selective cyclooxygenase 2 inhibitors. | Arthritis and rheumatism 20021201 |
Modifiable risk factors for colon cancer. | Gastroenterology clinics of North America 20021201 |
Cyclooxygenase (COX)-2 and granulosa cell apoptosis in vitro. | Journal of assisted reproduction and genetics 20021201 |
Acute pancreatitis: a rare complication of celecoxib. | Internal medicine journal 20021201 |
Practical considerations for the use of nonsteroidal anti-inflammatory drugs and cyclo-oxygenase-2 inhibitors in hypertension and kidney disease. | The Canadian journal of cardiology 20021201 |
Capecitabine and radiation therapy for advanced gastrointestinal malignancies. | Oncology (Williston Park, N.Y.) 20021201 |
Effect of celecoxib on capecitabine-induced hand-foot syndrome and antitumor activity. | Oncology (Williston Park, N.Y.) 20021201 |
Enthalpy relaxation studies of celecoxib amorphous mixtures. | Pharmaceutical research 20021201 |
New directions in symptomatic therapy for patients with osteoarthritis and rheumatoid arthritis. | Seminars in arthritis and rheumatism 20021201 |
Anti-inflammatory agents and renal function. | Seminars in arthritis and rheumatism 20021201 |
Effect of the selective COX-2 inhibitors, celecoxib and rofecoxib in rat acute models of inflammation. | Inflammation research : official journal of the European Histamine Research Society ... [et al.] 20021201 |
A 12-month, multicenter, prospective, open-label trial of radiographic analysis of disease progression in osteoarthritis of the knee or hip in patients receiving celecoxib. | Clinical therapeutics 20021201 |
Celecoxib-induced upper gastrointestinal hemorrhage and ulceration. | Southern medical journal 20021201 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20021201 |
The design of a randomized, placebo-controlled trial of celecoxib in preprostatectomy men with clinically localized adenocarcinoma of the prostate. | Clinical prostate cancer 20021201 |
Developments in antipsychotic therapy with regard to hypotheses for schizophrenia. | Dialogues in clinical neuroscience 20021201 |
Direct evidence for a role of cyclooxygenase 2-derived prostaglandin E2 in human head and neck xenograft tumors. | Cancer research 20021115 |
[A new drug approach approved in the USA. Cox-2 inhibitor in intestinal cancer]. | MMW Fortschritte der Medizin 20021114 |
Initial patterns of use of COX-2 inhibitors by elderly patients in Ontario: findings and implications. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20021112 |
The double-edged sword of COX-2 selective NSAIDs. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20021112 |
[Celebra and the CLASS trial--a scandal!]. | Ugeskrift for laeger 20021111 |
Selective cyclooxygenase-2 inhibitors show a differential ability to inhibit proliferation and induce apoptosis of colon adenocarcinoma cells. | FEBS letters 20021106 |
Expression of cyclooxygenase-2 (COX-2) in tumour and stroma compartments in cervical cancer: clinical implications. | British journal of cancer 20021104 |
Rofecoxib improves quality of life in patients with hip or knee osteoarthritis. | Swiss medical weekly 20021102 |
Celecoxib, safe in NSAID intolerance. | Allergy 20021101 |
Inhibition of cyclooxygenase-2 ameliorates the severity of pancreatitis and associated lung injury. | American journal of physiology. Gastrointestinal and liver physiology 20021101 |
Delta-opioid receptor-induced late preconditioning is mediated by cyclooxygenase-2 in conscious rabbits. | American journal of physiology. Heart and circulatory physiology 20021101 |
Ulcerogenic influence of selective cyclooxygenase-2 inhibitors in the rat stomach with adjuvant-induced arthritis. | The Journal of pharmacology and experimental therapeutics 20021101 |
Cellular distribution and contribution of cyclooxygenase COX-2 to diabetogenesis in NOD mouse. | Cell and tissue research 20021101 |
Effects of celecoxib and rofecoxib on blood pressure and edema in patients > or =65 years of age with systemic hypertension and osteoarthritis. | The American journal of cardiology 20021101 |
Cyclooxygenase-2-derived lipoxin A4 increases gastric resistance to aspirin-induced damage. | Gastroenterology 20021101 |
Nephrotic syndrome and interstitial nephritis associated with celecoxib. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20021101 |
Selective inhibitors of cyclo-oxygenase-2 (COX-2) induce hypoalgesia in a rat paw model of inflammation. | British journal of pharmacology 20021101 |
Rapid potentiation of endothelium-dependent vasodilation by estradiol in postmenopausal women is mediated via cyclooxygenase 2. | The Journal of clinical endocrinology and metabolism 20021101 |
Single-dose and steady-state pharmacokinetics of celecoxib in children. | Clinical pharmacology and therapeutics 20021101 |
A clinical audit of the prescribing of celecoxib and rofecoxib in Australian rural general practice. | British journal of clinical pharmacology 20021101 |
COX-2 inhibitors and their role in gynecology. | Obstetrical & gynecological survey 20021101 |
Treatment of rheumatoid arthritis and osteoarthritis with COX-2-selective inhibitors: a managed care perspective. | The American journal of managed care 20021101 |
Gastrointestinal outcomes: evidence for risk reduction in patients using coxibs. | The American journal of managed care 20021101 |
Spherical crystallization of celecoxib. | Drug development and industrial pharmacy 20021101 |
Induction of cyclooxygenase-2 in Ras-transformed human mammary epithelial cells undergoing apoptosis. | Annals of the New York Academy of Sciences 20021101 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20021101 |
Cyclooxygenase-2 inhibition with celecoxib enhances antitumor efficacy and reduces diarrhea side effect of CPT-11. | Cancer research 20021015 |
[At what care level are cyclo-oxygenase-2 inhibitors prescribed?]. | Atencion primaria 20021015 |
[Reduction of severe gastro-intestinal complications after the use of celecoxib:evidence available in the literature]. | Atencion primaria 20021015 |
Cyclooxygenase-2 inhibitor celecoxib inhibits promotion of mammary tumorigenesis in rats fed a high fat diet rich in n-6 polyunsaturated fatty acids. | Cancer letters 20021008 |
Isomeric acetoxy analogues of rofecoxib: a novel class of highly potent and selective cyclooxygenase-2 inhibitors. | Bioorganic & medicinal chemistry letters 20021007 |
[Celecoxib and the CLASS trial]. | Ugeskrift for laeger 20021007 |
COX-2 selective non-steroidal anti-inflammatory drugs and risk of serious coronary heart disease. | Lancet (London, England) 20021005 |
[Financial interests characterize published reports on coxiber. Whom can we rely on?]. | Lakartidningen 20021003 |
[The CLASS study and its scientific statement. Ethical publishing rules neglected]. | Lakartidningen 20021003 |
Blue rubber bleb nevus syndrome. | Gastrointestinal endoscopy 20021001 |
Proapoptotic and antiproliferative potential of selective cyclooxygenase-2 inhibitors in human liver tumor cells. | Hepatology (Baltimore, Md.) 20021001 |
Pharmacological and pharmacokinetic evaluation of celecoxib prodrugs in rats. | Biopharmaceutics & drug disposition 20021001 |
Celecoxib, a selective cyclooxygenase 2 inhibitor, protects against human epidermal growth factor receptor 2 (HER-2)/neu-induced breast cancer. | Cancer research 20021001 |
Celecoxib reduces pulmonary inflammation but not lung tumorigenesis in mice. | Carcinogenesis 20021001 |
The effect of cyclooxygenase-2 inhibitors on spinal fusion. | The Journal of bone and joint surgery. American volume 20021001 |
Oxidation of celecoxib by polymorphic cytochrome P450 2C9 and alcohol dehydrogenase. | British journal of clinical pharmacology 20021001 |
COX-2-specific inhibitors: prescribing patterns in a large managed care health system and strategies to minimize costs. | The American journal of managed care 20021001 |
HMO drug formulary access increases for COX-2s. | Managed care (Langhorne, Pa.) 20021001 |
Comparison of the baseline cardiovascular risk profile among hypertensive patients prescribed COX-2-specific inhibitors or nonspecific NSAIDs: data from real-life practice. | The American journal of managed care 20021001 |
Blood pressure destabilization and related healthcare utilization among hypertensive patients using nonspecific NSAIDs and COX-2-specific inhibitors. | The American journal of managed care 20021001 |
Cost of heart failure among hypertensive users of nonspecific NSAIDs and COX-2-specific inhibitors. | The American journal of managed care 20021001 |
Differences between COX-2-specific inhibitors: clinical and economic implications. | The American journal of managed care 20021001 |
Toxic epidermal necrolysis due to administration of celecoxib (Celebrex). | Southern medical journal 20021001 |
A comparison of rofecoxib versus celecoxib in treating pain after dental surgery: a single-center, randomized, double-blind, placebo- and active-comparator-controlled, parallel-group, single-dose study using the dental impaction pain model. | Clinical therapeutics 20021001 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20021001 |
[Anti-inflammatory non-steroidal selective cyclooxygenase 2 inhibitors and gastroduodenal lesions]. | Presse medicale (Paris, France : 1983) 20020928 |
Efficacy and safety of COX 2 inhibitors. | BMJ (Clinical research ed.) 20020921 |
Efficacy, tolerability, and upper gastrointestinal safety of celecoxib for treatment of osteoarthritis and rheumatoid arthritis: systematic review of randomised controlled trials. | BMJ (Clinical research ed.) 20020921 |
Observational study of upper gastrointestinal haemorrhage in elderly patients given selective cyclo-oxygenase-2 inhibitors or conventional non-steroidal anti-inflammatory drugs. | BMJ (Clinical research ed.) 20020921 |
[Celecoxib and the CLASS study--a statement]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20020920 |
[Celecoxib and the CLASS study--worse and worse...]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20020920 |
The cyclo-oxygenase-2 inhibitor celecoxib perturbs intracellular calcium by inhibiting endoplasmic reticulum Ca2+-ATPases: a plausible link with its anti-tumour effect and cardiovascular risks. | The Biochemical journal 20020915 |
[Analgesic in osteoporosis. Why so conservative with dosage?]. | MMW Fortschritte der Medizin 20020905 |
Anti-inflammatory agents in Alzheimer's disease. | Current neurology and neuroscience reports 20020901 |
Ca2+- and PKC-dependent stimulation of PGE2 synthesis by deoxycholic acid in human colonic fibroblasts. | American journal of physiology. Gastrointestinal and liver physiology 20020901 |
Pharmacology of celecoxib in rat brain after kainate administration. | The Journal of pharmacology and experimental therapeutics 20020901 |
Distinct roles for cyclooxygenases 1 and 2 in interleukin-1-induced behavioral changes. | The Journal of pharmacology and experimental therapeutics 20020901 |
Renal effects on a solitary kidney of specific inhibition of cyclooxygenease-2 after 24 h of complete ureteric obstruction in rats. | Urological research 20020901 |
Robin goodfellow. | Rheumatology (Oxford, England) 20020901 |
Celecoxib does not affect the antiplatelet activity of aspirin in healthy volunteers. | Journal of clinical pharmacology 20020901 |
Effects of celecoxib and diclofenac on blood pressure, renal function, and vasoactive prostanoids in young and elderly subjects. | Journal of clinical pharmacology 20020901 |
Toxic epidermal necrolysis after celecoxib therapy. | Pharmacotherapy 20020901 |
A prospective randomized safety trial of celecoxib for treatment of preterm labor. | American journal of obstetrics and gynecology 20020901 |
Chemoprevention of superficial bladder cancer. | Critical reviews in oncology/hematology 20020901 |
Effect of selective cyclooxygenase-2 inhibition on the development of ligature-induced periodontitis in rats. | Journal of periodontology 20020901 |
Validated HPLC method for the determination of celecoxib in human serum and its application in a clinical pharmacokinetic study. | Die Pharmazie 20020901 |
The AGS' fondness for celecoxib. | Journal of the American Geriatrics Society 20020901 |
Celecoxib (celebrex) increases canine lower esophageal sphincter pressure. | The Journal of surgical research 20020901 |
Gateways to Clinical Trials. | Methods and findings in experimental and clinical pharmacology 20020901 |
Differential regulation of prostacyclin and thromboxane by dexamethasone and celecoxib during oxidative stress in newborn rabbits. | Prostaglandins & other lipid mediators 20020901 |
COX-2 inhibition and the control of pain. | Current opinion in investigational drugs (London, England : 2000) 20020901 |
Do selective cyclo-oxygenase inhibitors eliminate the adverse events associated with nonsteroidal anti-inflammatory drug therapy? | European journal of gastroenterology & hepatology 20020901 |
Clinical profiles of celecoxib and rofecoxib in the rheumatic diseases. | Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20020901 |
COX-2-specific inhibitors and the kidney: effect on hypertension and oedema. | Journal of hypertension. Supplement : official journal of the International Society of Hypertension 20020901 |
NSAIDS for prevention? Protecting the brain while killing pain? | Science (New York, N.Y.) 20020823 |
Inflammation and cancer, the mastocytoma P815 tumor model revisited: triggering of macrophage activation in vivo with pro-tumorigenic consequences. | International journal of cancer 20020810 |
Celecoxib induces apoptosis by inhibiting 3-phosphoinositide-dependent protein kinase-1 activity in the human colon cancer HT-29 cell line. | The Journal of biological chemistry 20020802 |
Efficacy and tolerability of nonprescription ibuprofen versus celecoxib for dental pain. | Journal of clinical pharmacology 20020801 |
Tracing the origins of COX-2 inhibitors' structures. | Current medicinal chemistry 20020801 |
Selecting new drugs for pain control: evidence-based decisions or clinical impressions? | Journal of the American Dental Association (1939) 20020801 |
COX-2 inhibitors: better than traditional NSAIDs? Vioxx and Celebrex may be no less risky than NSAIDs. | Health news (Waltham, Mass.) 20020801 |
The risk of cardiovascular thrombotic events with selective cyclooxygenase-2 inhibitors. | Arthritis and rheumatism 20020801 |
The safety of celecoxib in patients with aspirin-sensitive asthma. | Arthritis and rheumatism 20020801 |
Efficacy of celecoxib versus ibuprofen in the treatment of acute pain: a multicenter, double-blind, randomized controlled trial in acute ankle sprain. | American journal of orthopedics (Belle Mead, N.J.) 20020801 |
A stability-indicating HPLC method to determine Celecoxib in capsule formulations. | Drug development and industrial pharmacy 20020801 |
Positive patch test reactions to celecoxib may be due to irritation and do not correlate with the results of oral provocation. | Contact dermatitis 20020801 |
Non-steroidal anti-inflammatory drugs in orofacial pain management--an update. | SADJ : journal of the South African Dental Association = tydskrif van die Suid-Afrikaanse Tandheelkundige Vereniging 20020801 |
Chemopreventive effect of celecoxib and expression of cyclooxygenase-1 and cyclooxygenase-2 on chemically-induced rat mammary tumours. | International journal of experimental pathology 20020801 |
Chemoprevention of large bowel carcinogenesis; the role of control of cell proliferation and significance of beta-catenin-accumulated crypts as a new biomarker. | European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 20020801 |
[Selective cyclooxygenase-2 inhibitors and the digestive tract]. | La Tunisie medicale 20020801 |
The role of rofecoxib, a cyclooxygenase-2-specific inhibitor, for the treatment of non-cancer pain: a review. | The journal of pain : official journal of the American Pain Society 20020801 |
Cholestatic hepatitis in association with celecoxib. Classification of drug associated liver dysfunction is questionable. | BMJ (Clinical research ed.) 20020727 |
[Mobility and quality of life for arthrosis and rheumatism patients. Modern pain management with selective cox-2 inhibition]. | MMW Fortschritte der Medizin 20020726 |
Are selective COX 2 inhibitors superior to traditional NSAIDs? Rofecoxib did not provide unequivocal benefit over traditional NSAIDs. | BMJ (Clinical research ed.) 20020720 |
Are selective COX 2 inhibitors superior to traditional NSAIDs? Pharmacia's response to editorial. | BMJ (Clinical research ed.) 20020720 |
Are selective COX 2 inhibitors superior to traditional NSAIDs? Little is known about COX 2 inhibitors. | BMJ (Clinical research ed.) 20020720 |
Are selective COX 2 inhibitors superior to traditional NSAIDs? Both the CLASS and VIGOR trials support the COX 2 hypothesis. | BMJ (Clinical research ed.) 20020720 |
Cyclo-oxygenase inhibition reduces tumour growth and metastasis in an orthotopic model of breast cancer. | British journal of cancer 20020715 |
Seminal pharmaceutical trials: maintaining masking in analysis. | Lancet (London, England) 20020713 |
N-acetylcysteine and celecoxib lessen cadmium cytotoxicity which is associated with cyclooxygenase-2 up-regulation in mouse neuronal cells. | The Journal of biological chemistry 20020712 |
Celecoxib-induced cholestatic hepatotoxicity in a patient with cirrhosis. | Annals of internal medicine 20020702 |
Selective COX-2 inhibition prevents proinflammatory cytokine-induced cartilage damage. | Rheumatology (Oxford, England) 20020701 |
Nonsteroidal antiinflammatory drug starter packs for chronic musculoskeletal pain. | Pharmacotherapy 20020701 |
In vivo selectivity of a selective cyclooxygenase 2 inhibitor in the oral surgery model. | Clinical pharmacology and therapeutics 20020701 |
Comparison of rofecoxib, celecoxib, and naproxen on renal function in elderly subjects receiving a normal-salt diet. | Clinical pharmacology and therapeutics 20020701 |
Anti-hyperalgesic effects of nimesulide: studies in rats and humans. | International journal of clinical practice. Supplement 20020701 |
Designing selective COX-2 inhibitors: molecular modeling approaches. | Current opinion in drug discovery & development 20020701 |
Role of COX-2 inhibitors in the evolution of acute pain management. | Journal of pain and symptom management 20020701 |
[Allergic vasculitis following ingestion of celecoxib?]. | Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete 20020701 |
Review of the selective COX-2 inhibitors celecoxib and rofecoxib: focus on clinical aspects. | CJEM 20020701 |
Digging for data from the COX-2 trials. | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20020625 |
What's all the fuss? Safety concerns about COX-2 inhibitors rofecoxib (Vioxx) and celecoxib (Celebrex). | CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne 20020625 |
Medication toxicity among patients with ankylosing spondylitis. | Arthritis and rheumatism 20020615 |
[Hyperkalemia and celecoxib]. | Medicina clinica 20020608 |
Overexpression of cyclooxygenase-2 (COX-2) in human primitive neuroectodermal tumors: effect of celecoxib and rofecoxib. | Cancer letters 20020606 |
A randomised, double blind, placebo controlled study of celecoxib, a selective cyclooxygenase 2 inhibitor, on duodenal polyposis in familial adenomatous polyposis. | Gut 20020601 |
Are selective COX 2 inhibitors superior to traditional non steroidal anti-inflammatory drugs? | BMJ (Clinical research ed.) 20020601 |
Beneficial antipsychotic effects of celecoxib add-on therapy compared to risperidone alone in schizophrenia. | The American journal of psychiatry 20020601 |
Celecoxib-induced acute interstitial nephritis. | American journal of kidney diseases : the official journal of the National Kidney Foundation 20020601 |
COX-1 and 2, intestinal integrity, and pathogenesis of nonsteroidal anti-inflammatory drug enteropathy in mice. | Gastroenterology 20020601 |
Celecoxib, a cyclooxygenase 2 inhibitor as a potential chemopreventive to UV-induced skin cancer: a study in the hairless mouse model. | Archives of dermatology 20020601 |
Cyclooxygenase inhibitors for skin cancer prevention: are they beneficial enough? | Archives of dermatology 20020601 |
Coxibs + oral anticoagulants: risk of interaction. | Prescrire international 20020601 |
New studies highlight benefit of Xeloda in new combination treatments for colorectal cancer. | Expert review of anticancer therapy 20020601 |
Physician-reported management of edema and destabilized blood pressure in cyclooxygenase-2-specific inhibitor users with osteoarthritis and treated hypertension. | Clinical therapeutics 20020601 |
Hemicrania continua responds to cyclooxygenase-2 inhibitors. | Headache 20020601 |
Effect of cyclooxygenase inhibitors in postoperative ileus: an experimental study. | Methods and findings in experimental and clinical pharmacology 20020601 |
Gateways to Clinical Trials. June 2002. | Methods and findings in experimental and clinical pharmacology 20020601 |
Myopathy Associated With HMG-CoA Reductase Inhibitors (Statins): A Series of 10 Patients and Review of the Literature. | Journal of clinical neuromuscular disease 20020601 |
Cost-effectiveness of replacing NSAIDs with coxibs: diclofenac and celecoxib in rheumatoid arthritis. | Expert review of pharmacoeconomics & outcomes research 20020601 |
[Coxib spares the stomach. This is true also for patients with preventive aspirin administration]. | MMW Fortschritte der Medizin 20020516 |
Determination of celecoxib, a COX-2 inhibitor, in pharmaceutical dosage forms by MEKC. | Journal of pharmaceutical and biomedical analysis 20020515 |
Determination of celecoxib in pharmaceutical formulations using UV spectrophotometry and liquid chromatography. | Journal of pharmaceutical and biomedical analysis 20020515 |
Chronic gastric ulcer healing in rats subjected to selective and non-selective cyclooxygenase-2 inhibitors. | European journal of pharmacology 20020503 |
Cyclooxygenase inhibition: between the devil and the deep blue sea. | Gut 20020501 |
Selective cyclooxygenase-2 inhibition impairs glomerular capillary healing in experimental glomerulonephritis. | Journal of the American Society of Nephrology : JASN 20020501 |
Hyaluronan increases glomerular cyclooxygenase-2 protein expression in a p38 MAP-kinase-dependent process. | Kidney international 20020501 |
The efficacy of premedication with celecoxib and acetaminophen in preventing pain after otolaryngologic surgery. | Anesthesia and analgesia 20020501 |
Translational medicine: targetting cyclo-oxygenase isozymes to prevent cancer. | QJM : monthly journal of the Association of Physicians 20020501 |
Migratory pulmonary infiltrates in a patient with rheumatoid arthritis. | Thorax 20020501 |
Cyclooxygenase-2 overexpression in the skin of transgenic mice results in suppression of tumor development. | Cancer research 20020501 |
Regulation of retinal vascular endothelial growth factor and receptors in rabbits exposed to hyperoxia. | Investigative ophthalmology & visual science 20020501 |
Specific cyclooxygenase-2 inhibitors: what have we learned since they came into widespread clinical use? | Current opinion in rheumatology 20020501 |
Celecoxib-induced erythema multiforme with glyburide cross-reactivity. | Pharmacotherapy 20020501 |
Increase in lifetime adverse drug reactions, service utilization, and disease severity among patients who will start COX-2 specific inhibitors: quantitative assessment of channeling bias and confounding by indication in 6689 patients with rheumatoid arthritis and osteoarthritis. | The Journal of rheumatology 20020501 |
Anti-implantation effects of indomethacin and celecoxib in rats. | Contraception 20020501 |
[Specific inhibitors of cyclooxygenase type 2] ]. | Vnitrni lekarstvi 20020501 |
Studies on the development of colon-targeted delivery systems for celecoxib in the prevention of colorectal cancer. | Journal of drug targeting 20020501 |
Alteration of gastric ulcerogenic and healing responses in rats with adjuvant-induced arthritis. | Japanese journal of pharmacology 20020501 |
Gateways to clinical trials. | Methods and findings in experimental and clinical pharmacology 20020501 |
Current application of selective COX-2 inhibitors in cancer prevention and treatment. | Oncology (Williston Park, N.Y.) 20020501 |
Inhibition of COX-2 reduces the age-dependent increase of hippocampal inflammatory markers, corticosterone secretion, and behavioral impairments in the rat. | Journal of neuroscience research 20020501 |
[Dexketoprofene, selective cox-1 inhibitor nsaids, without gastrointestinal injury in rats]. | Acta gastroenterologica Latinoamericana 20020501 |
Antiangiogenic and chemopreventive activities of celecoxib in oral carcinoma cell. | The Laryngoscope 20020501 |
Cardiovascular hazard of selective COX-2 inhibitors: myth or reality? | Expert opinion on drug safety 20020501 |
Characterization, quantification, and bioactivities of anthocyanins in Cornus species. | Journal of agricultural and food chemistry 20020424 |
COX-2 in cancer--a player that's defining the rules. | Journal of the National Cancer Institute 20020417 |
Cyclooxygenase-2, player or spectator in cyclooxygenase-2 inhibitor-induced apoptosis in prostate cancer cells. | Journal of the National Cancer Institute 20020417 |
Selective cyclooxygenase (COX)-1 or COX-2 inhibitors control metastatic disease in a murine model of breast cancer. | Cancer research 20020415 |
[Celecoxib]. | Deutsche medizinische Wochenschrift (1946) 20020412 |
Rofecoxib vs celecoxib vs acetaminophen for treatment of osteoarthritis. | JAMA 20020410 |
Rofecoxib vs celecoxib vs acetaminophen for treatment of osteoarthritis. | JAMA 20020410 |
Inhibitor of cyclooxygenase-2 induces cell-cycle arrest in the epithelial cancer cell line via up-regulation of cyclin dependent kinase inhibitor p21. | British journal of cancer 20020408 |
Cyclooxygenase inhibition in cancer--a blind alley or a new therapeutic reality? | The New England journal of medicine 20020404 |
[Symptomatic therapy of arthrosis and rheumatoid arthritis. Who will benefit from Coxib?]. | MMW Fortschritte der Medizin 20020404 |
Lamin B, caspase-3 activity, and apoptosis induction by a combination of HMG-CoA reductase inhibitor and COX-2 inhibitors: a novel approach in developing effective chemopreventive regimens. | International journal of oncology 20020401 |
The MDR phenotype is associated with the expression of COX-2 and iNOS in a human hepatocellular carcinoma cell line. | Hepatology (Baltimore, Md.) 20020401 |
The role of cyclooxygenase-1 and -2 in the rat formalin test. | Anesthesia and analgesia 20020401 |
Dyspepsia tolerability from the patients' perspective: a comparison of celecoxib with diclofenac. | Alimentary pharmacology & therapeutics 20020401 |
Celecoxib exhibits the greatest potency amongst cyclooxygenase (COX) inhibitors for growth inhibition of COX-2-negative hematopoietic and epithelial cell lines. | Cancer research 20020401 |
Metabolism of human articular chondrocytes cultured in alginate beads. Longterm effects of interleukin 1beta and nonsteroidal antiinflammatory drugs. | The Journal of rheumatology 20020401 |
Effects of celecoxib on ambulatory blood pressure in hypertensive patients on ACE inhibitors. | Hypertension (Dallas, Tex. : 1979) 20020401 |
Which is most effective of osteoarthritis of the knee: rofecoxib, celecoxib, or acetaminophen? | The Journal of family practice 20020401 |
Gastrointestinal safety of coxibs and outcomes studies: what's the verdict? | Journal of pain and symptom management 20020401 |
Renal effects of cyclooxygyenase-2-selective inhibitors. | Journal of pain and symptom management 20020401 |
Cox-2 inhibitors: today and tomorrow. | The American journal of the medical sciences 20020401 |
Safety of selective cyclooxygenase-2 inhibitors in inflammatory bowel disease. | The American journal of gastroenterology 20020401 |
Considerations for the safe prescribing and use of COX-2-specific inhibitors. | The Medical journal of Australia 20020401 |
Celecoxib with chemotherapy in colorectal cancer. | Oncology (Williston Park, N.Y.) 20020401 |
Modulation of inflammatory paw oedema by cysteamine in the rat. | Pharmacological research 20020401 |
Bioactivity of alkamides isolated from Echinacea purpurea (L.) Moench. | Phytomedicine : international journal of phytotherapy and phytopharmacology 20020401 |
COX-2 inhibitor for the treatment of idiopathic stabbing headache secondary to cerebrovascular diseases. | Cephalalgia : an international journal of headache 20020401 |
Clinical experience with cyclooxygenase-2 inhibitors. | Rheumatology (Oxford, England) 20020401 |
Athletes, nonsteroidal anti-inflammatory drugs, coxibs, and the gastrointestinal tract. | Current sports medicine reports 20020401 |
Case of cholestatic hepatitis with celecoxib did not fulfil international criteria. | BMJ (Clinical research ed.) 20020330 |
[First spontaneous reports of adverse reactions to the new selective COX-2 non-steroidal anti-inflammatory drugs]. | Medicina clinica 20020330 |
Identification of novel cyclooxygenase-2 selective inhibitors using pharmacophore models. | Journal of medicinal chemistry 20020328 |
4-(4-cycloalkyl/aryl-oxazol-5-yl)benzenesulfonamides as selective cyclooxygenase-2 inhibitors: enhancement of the selectivity by introduction of a fluorine atom and identification of a potent, highly selective, and orally active COX-2 inhibitor JTE-522(1). | Journal of medicinal chemistry 20020328 |
Inducible nitric oxide synthase modulates cyclooxygenase-2 activity in the heart of conscious rabbits during the late phase of ischemic preconditioning. | Circulation research 20020322 |
Nonsteroidal anti-inflammatory drugs, coxibs, and cardio-renal physiology: a mechanism-based approach. | The American journal of cardiology 20020321 |
An evidence-based evaluation of the gastrointestinal safety of coxibs. | The American journal of cardiology 20020321 |
Cyclooxygenase-2 inhibition and renal physiology. | The American journal of cardiology 20020321 |
Effects of nonsteroidal anti-inflammatory drug therapy on blood pressure and peripheral edema. | The American journal of cardiology 20020321 |
Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20020315 |
Fatal allergic vasculitis associated with celecoxib. | Lancet (London, England) 20020309 |
Simple and sensitive method for the determination of celecoxib in human serum by high-performance liquid chromatography with fluorescence detection. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20020305 |
Up-regulation of cyclooxygenase-2 by inhibition of cyclooxygenase-1: a key to nonsteroidal anti-inflammatory drug-induced intestinal damage. | The Journal of pharmacology and experimental therapeutics 20020301 |
The advancement of cancer chemoprevention by revision of clinical trial strategies. | Panminerva medica 20020301 |
Cyclooxygenase-2 activity altered the cell-surface carbohydrate antigens on colon cancer cells and enhanced liver metastasis. | Cancer research 20020301 |
Selective cyclooxygenase-2 blocker delays healing of esophageal ulcers in rats and inhibits ulceration-triggered c-Met/hepatocyte growth factor receptor induction and extracellular signal-regulated kinase 2 activation. | The American journal of pathology 20020301 |
Nitric oxide, anti-inflammatory drugs on renal prostaglandins and cyclooxygenase-2. | Hypertension (Dallas, Tex. : 1979) 20020301 |
Anaphylaxis to celecoxib. | Allergy 20020301 |
Inhibition of cyclo-oxygenase-2 exacerbates ischaemia-induced acute myocardial dysfunction in the rabbit. | British journal of pharmacology 20020301 |
Gastroprotective therapy and risk of gastrointestinal ulcers: risk reduction by COX-2 therapy. | The Journal of rheumatology 20020301 |
Selective cyclooxygenase-2 (COX-2) inhibitors and potential risk of cardiovascular events. | Biochemical pharmacology 20020301 |
A rat model of bone cancer pain. | Pain 20020301 |
A comparison of the renal and cardiovascular safety of celecoxib and rofecoxib. | Clinical therapeutics 20020301 |
Structure-based design of cyclooxygenase-2 selectivity into ketoprofen. | Bioorganic & medicinal chemistry letters 20020225 |
[Safety of celecoxib and rofecoxib: a critical overview]. | Medicina clinica 20020223 |
Comparison of the antinociceptive effect of celecoxib, diclofenac and resveratrol in the formalin test. | Life sciences 20020222 |
COX-2 inhibitors: cancer trials test new uses for pain drug. | Journal of the National Cancer Institute 20020220 |
Nonsteroidal anti-inflammatory drugs as anticancer agents: mechanistic, pharmacologic, and clinical issues. | Journal of the National Cancer Institute 20020220 |
[A critical evaluation of side effect data on COX-2 inhibitors]. | Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20020220 |
Comparison of thromboembolic events in patients treated with celecoxib, a cyclooxygenase-2 specific inhibitor, versus ibuprofen or diclofenac. | The American journal of cardiology 20020215 |
[Improper use of selective COX-2 inhibitor NSAIDs]. | Atencion primaria 20020215 |
Protective effects of Celecoxib on lung injury and red blood cells modification induced by carrageenan in the rat. | Biochemical pharmacology 20020215 |
Estimation of binding affinities for celecoxib analogues with COX-2 via Monte Carlo-extended linear response. | Bioorganic & medicinal chemistry letters 20020211 |
Why do cyclo-oxygenase-2 inhibitors cause cardiovascular events? | Journal of the American College of Cardiology 20020206 |
Stability-indicating methods for the determination of doxazosin mezylate and celecoxib. | Journal of pharmaceutical and biomedical analysis 20020201 |
Investigation of the pharmacokinetics of celecoxib by liquid chromatography-mass spectrometry. | Biomedical chromatography : BMC 20020201 |
Cyclooxygenase-2 inhibition by celecoxib reduces proliferation and induces apoptosis in angiogenic endothelial cells in vivo. | Cancer research 20020201 |
Effects of a selective cyclooxygenase-2 inhibitor, celecoxib, on bone resorption and osteoclastogenesis in vitro. | Biochemical pharmacology 20020201 |
Cyclooxygenase-1 derived prostaglandins are involved in the maintenance of renal function in rats with cirrhosis and ascites. | British journal of pharmacology 20020201 |
New cyclooxygenase-2 inhibitors for treatment of experimental autoimmune neuritis. | Muscle & nerve 20020201 |
Selective inhibition of COX-2 is beneficial to mice infected intranasally with VSV. | Prostaglandins & other lipid mediators 20020201 |
[Celecoxib induced toxiderma with positive patch-test]. | Annales de dermatologie et de venereologie 20020201 |
[Neutrophil-endothelium interaction]. | Nihon rinsho. Japanese journal of clinical medicine 20020201 |
Highlights of the 22nd French pharmacovigilance meeting. | Prescrire international 20020201 |
[New nonsteroidal antiinflammatory drugs in rheumatoid arthritis]. | Annales de medecine interne 20020201 |
Valdecoxib (Pharmacia). | Current opinion in investigational drugs (London, England : 2000) 20020201 |
Chemoprevention of bladder cancer. | The Urologic clinics of North America 20020201 |
New directions in pain management. | Drugs of today (Barcelona, Spain : 1998) 20020201 |
COX-2 inhibition and thrombotic tendency. | The Medical journal of Australia 20020121 |
Efficacy of rofecoxib, celecoxib, and acetaminophen in osteoarthritis of the knee: a randomized trial. | JAMA 20020102 |
Current treatment of juvenile rheumatoid arthritis. | Pediatrics 20020101 |
Chemopreventive properties of a selective inducible nitric oxide synthase inhibitor in colon carcinogenesis, administered alone or in combination with celecoxib, a selective cyclooxygenase-2 inhibitor. | Cancer research 20020101 |
Chemoprevention of colorectal cancer. | The American journal of gastroenterology 20020101 |
Celecoxib-induced nonoliguric acute renal failure. | The Annals of pharmacotherapy 20020101 |
Cutaneous drug reaction case reports: from the world literature. | American journal of clinical dermatology 20020101 |
Acute manic psychosis induced by triple therapy for H. pylori. | The Journal of the American Board of Family Practice 20020101 |
Upper gastrointestinal tolerability of celecoxib compared with diclofenac in the treatment of osteoarthritis and rheumatoid arthritis. | Clinical and experimental rheumatology 20020101 |
Anti-inflammatory medications: selective COX-2 inhibitors. | The Journal of the American Academy of Orthopaedic Surgeons 20020101 |
Cyclo-oxygenase-2 inhibitors and the kidney: a case for caution. | Drug safety 20020101 |
Comparative analgesia, cardiovascular and renal effects of celecoxib, rofecoxib and acetaminophen (paracetamol). | Current pharmaceutical design 20020101 |
Gastrointestinal safety of selective COX-2 inhibitors. | Current pharmaceutical design 20020101 |
Celecoxib: a specific COX-2 inhibitor with anticancer properties. | Cancer control : journal of the Moffitt Cancer Center 20020101 |
[Current post-marketing information. Effects and adverse effects of celecoxib]. | Pharmazie in unserer Zeit 20020101 |
Do standard doses of frequently prescribed drugs cause preventable adverse effects in women? | Journal of the American Medical Women's Association (1972) 20020101 |
Should celecoxib be contraindicated in patients who are allergic to sulfonamides? | Drug safety 20020101 |
A cyclooxegenase-2 inhibitor impairs ligament healing in the rat. | The American journal of sports medicine 20020101 |
Efficacy of celecoxib in treating symptoms of viral pharyngitis: a double-blind, randomized study of celecoxib versus diclofenac. | The Journal of international medical research 20020101 |
A multinational randomized, controlled, clinical trial of etoricoxib in the treatment of rheumatoid arthritis [ISRCTN25142273]. | BMC family practice 20020101 |
Sildenafil (Viagra) for male erectile dysfunction: a meta-analysis of clinical trial reports. | BMC urology 20020101 |
Reducing the risk of colorectal cancer by intervening in the process of carcinogenesis: a status report. | Cancer journal (Sudbury, Mass.) 20020101 |
Cutaneous vasculitis related to celecoxib. | Dermatology (Basel, Switzerland) 20020101 |
COX-2-selective inhibitors in the treatment of arthritis. | Cleveland Clinic journal of medicine 20020101 |
Gastrointestinal safety and tolerability of nonselective nonsteroidal anti-inflammatory agents and cyclooxygenase-2-selective inhibitors. | Cleveland Clinic journal of medicine 20020101 |
Outcomes studies of the gastrointestinal safety of cyclooxygenase-2 inhibitors. | Cleveland Clinic journal of medicine 20020101 |
Current perspective on the cardiovascular effects of coxibs. | Cleveland Clinic journal of medicine 20020101 |
Development and clinical application of COX-2-selective inhibitors for the treatment of osteoarthritis and rheumatoid arthritis. | Cleveland Clinic journal of medicine 20020101 |
COX-2 and prostanoid receptors: good targets for chemoprevention. | Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20020101 |
Novel approaches for colon cancer prevention by cyclooxygenase-2 inhibitors. | Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20020101 |
Is cyclooxygenase-2 important in skin carcinogenesis? | Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer 20020101 |
Celecoxib-associated torsade de pointes. | The Annals of pharmacotherapy 20020101 |
Rofecoxib, 25 mg/d, was more effective than rofecoxib, 12.5 mg/d, celecoxib, or acetaminophen in osteoarthritis of the knee. | ACP journal club 20020101 |
Renal failure associated with the use of celecoxib and rofecoxib. | Drug safety 20020101 |
New reports on dental analgesics. NSAIDs and cardiovascular effects, celecoxib for dental pain, and a new analgesic--tramadol with acetaminophen. | General dentistry 20020101 |
Effects of Celebrex and Zyflo on BOP-induced pancreatic cancer in Syrian hamsters. | Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 20020101 |
Celecoxib for systemic lupus erythematosus: case series and literature review of the use of NSAIDs in SLE. | Lupus 20020101 |
Chemoprevention in colorectal neoplasias: what is practical and feasible? | Digestive diseases (Basel, Switzerland) 20020101 |
Therapeutic utility of aspirin in the ApcMin/+ murine model of colon carcinogenesis. | BMC cancer 20020101 |
[Reactive polyarthritis and painful dermatographism caused by Helicobacter pylori]. | Revista alergia Mexico (Tecamachalco, Puebla, Mexico : 1993) 20020101 |
[Case report: reversible acute renal failure following therapy with both ketorolac (non-selective non-steroidal anti-inflammatory drug NSAID) and celecoxib (COX-2 selective) in the same patient]. | Giornale italiano di nefrologia : organo ufficiale della Societa italiana di nefrologia 20020101 |
Therapy of ankylosing spondylitis and other spondyloarthritides: established medical treatment, anti-TNF-alpha therapy and other novel approaches. | Arthritis research 20020101 |
Valdecoxib. | Reviews in gastroenterological disorders 20020101 |
Selective cyclo-oxygenase-2 inhibitors and myocardial infarction: how strong is the link? | Drug safety 20020101 |
Lithium toxicity: a potential interaction with celecoxib. | Internal medicine journal 20020101 |
Renal effects of cyclooxygenase-2 inhibition in fetal lambs. | Biology of the neonate 20020101 |
Labeling changes for arthritis drug. | FDA consumer 20020101 |
Efficacy and safety of diclofenac-cholestyramine and celecoxib in osteoarthritis. | Proceedings of the Western Pharmacology Society 20020101 |
COX-2-selective inhibitors: clinical relevance in surgical and acute pain. | European journal of anaesthesiology. Supplement 20020101 |
Do non-steroidal anti-inflammatory drugs and COX-2 selective inhibitors have different renal effects? | Journal of nephrology 20020101 |
Etoricoxib. | Drugs 20020101 |
Most effective colon cancer chemopreventive agents in rats: a systematic review of aberrant crypt foci and tumor data, ranked by potency. | Nutrition and cancer 20020101 |
[Safety of celecoxib administration]. | Reumatizam 20020101 |
Celecoxib for rheumatoid arthritis. | The Cochrane database of systematic reviews 20020101 |
Effects of Celebrex and Zyflo on liver metastasis and lipidperoxidation in pancreatic cancer in Syrian hamsters. | Clinical & experimental metastasis 20020101 |
The biochemical selectivity of novel COX-2 inhibitors in whole blood assays of COX-isozyme activity. | Current medical research and opinion 20020101 |
In vivo evaluation of guargum-based colon-targeted oral drug delivery systems of celecoxib in human volunteers. | European journal of drug metabolism and pharmacokinetics 20020101 |
Inhibition of ultraviolet light B-induced cutaneous inflammation by a specific cyclooxygenase-2 inhibitor. | Advances in experimental medicine and biology 20020101 |
Mechanism of inhibition of novel COX-2 inhibitors. | Advances in experimental medicine and biology 20020101 |
Ulcers, Helicobacter pylori infection, platelets and gastrointestinal complications of non-steroidal anti-inflammatory drugs: what are the connections? | The European journal of surgery. Supplement. : = Acta chirurgica. Supplement 20020101 |
Concerns about COX-2 painkillers. They're easier on the stomach, potentially harder on your heart. | Heart advisor 20020101 |
Cyclooxygenase-2 inducing Mcl-1-dependent survival mechanism in human lung adenocarcinoma CL1.0 cells. Involvement of phosphatidylinositol 3-kinase/Akt pathway. | The Journal of biological chemistry 20011228 |
Cardiovascular events and COX-2 inhibitors. | JAMA 20011212 |
[A pop-up menu linked to a computerized drug prescribing system. Prescribing pattern's feedback via a simple and quick method]. | Lakartidningen 20011212 |
The coxibs, selective inhibitors of cyclooxygenase-2. | The New England journal of medicine 20011206 |
COX-2 independent induction of cell cycle arrest and apoptosis in colon cancer cells by the selective COX-2 inhibitor celecoxib. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20011201 |
Journals should see original protocols for clinical trials. | BMJ (Clinical research ed.) 20011201 |
Effects of NSAIDs on cryoprobe-induced gastric ulcer healing in rats. | Alimentary pharmacology & therapeutics 20011201 |
Gastro-duodenal protection in an era of cyclo-oxygenase-2-selective nonsteroidal anti-inflammatory drugs. | European journal of gastroenterology & hepatology 20011201 |
A protective role for cyclooxygenase-2 in drug-induced liver injury in mice. | Chemical research in toxicology 20011201 |
COX-2 inhibitors: no pain, no heart gain? | Harvard heart letter : from Harvard Medical School 20011201 |
Quantification of nimesulide in human plasma by high-performance liquid chromatography/tandem mass spectrometry. Application to bioequivalence studies. | Journal of mass spectrometry : JMS 20011201 |
COX-2 inhibitors. Are they nonsteroidal anti-inflammatory drugs with a better safety profile? | Gastroenterology clinics of North America 20011201 |
GI events leading to death in association with celecoxib and rofecoxib. | The American journal of gastroenterology 20011201 |
The use and effect of analgesics in patients who regularly drink alcohol. | The American journal of managed care 20011201 |
Intracerebral hemorrhage following possible interaction between celecoxib and clopidogrel. | The Annals of pharmacotherapy 20011201 |
Celecoxib as adjunctive therapy for treatment of colorectal cancer. | The Annals of pharmacotherapy 20011201 |
Cyclooxygenase-1 and cyclooxygenase-2 selectivity of non-steroidal anti-inflammatory drugs: investigation using human peripheral monocytes. | The Journal of pharmacy and pharmacology 20011201 |
[Pharmacology of non-steroidal anti-inflammatory drugs and ENT pathology]. | Presse medicale (Paris, France : 1983) 20011201 |
[Current status of COX II inhibitors in therapy of rheumatoid arthritis in comparison with conventional non-steroidal anti-inflammatory agents. Attempt at an evaluation with regard to evidence-based medicine]. | Zeitschrift fur Rheumatologie 20011201 |
Reporting of 6-month vs 12-month data in a clinical trial of celecoxib. | JAMA 20011121 |
Reporting of 6-month vs 12-month data in a clinical trial of celecoxib. | JAMA 20011121 |
Pharmacological therapies for the treatment of osteoarthritis. | The Medical journal of Australia 20011119 |
Interstitial nephritis associated with celecoxib. | Lancet (London, England) 20011117 |
[Cox-2 inhibitors in the focus. Rofecoxib as effective as the 'classics']. | MMW Fortschritte der Medizin 20011115 |
[Side effects cause enormous costs. Expensive arthritis therapy]. | MMW Fortschritte der Medizin 20011115 |
Cardiovascular safety of COX-2 inhibitors. | The Medical letter on drugs and therapeutics 20011112 |
Celecoxib, a selective cyclo-oxygenase-2 inhibitor reduces the severity of experimental colitis induced by dinitrobenzene sulfonic acid in rats. | European journal of pharmacology 20011109 |
Acute gastrointestinal permeability responses to different non-steroidal anti-inflammatory drugs. | Gut 20011101 |
In vitro effects of cyclooxygenase inhibitors in whole blood of horses, dogs, and cats. | American journal of veterinary research 20011101 |
Urticaria and angioedema from cyclooxygenase-2 inhibitors. | The Journal of rheumatology 20011101 |
Inhibition of beta-catenin translocation in rodent colorectal tumors: a novel explanation for the protective effect of nonsteroidal antiinflammatory drugs in colorectal cancer. | Digestive diseases and sciences 20011101 |
Selective cyclo-oxygenase-2 inhibitor-induced oliguria: a postoperative complication. | Internal medicine journal 20011101 |
Effects of selective COX-1 and -2 inhibition on formalin-evoked nociceptive behaviour and prostaglandin E(2) release in the spinal cord. | Journal of neurochemistry 20011101 |
Arthritis. Should you be taking a COX-2 inhibitor? | Harvard health letter 20011101 |
Pain treatment with NSAIDs, primary focus on ibuprofen. | Clinical rheumatology 20011101 |
Celecoxib and rofecoxib. | Journal of the American Dental Association (1939) 20011101 |
COX-2 inhibitors compared and contrasted. | Expert opinion on pharmacotherapy 20011101 |
Aspirin and non-steroidal anti-inflammatory drugs inhibit amyloid-beta aggregation. | Neuroreport 20011029 |
Naphthalene derivatives: A new series of selective cyclooxygenase-2 inhibitors. | Bioorganic & medicinal chemistry letters 20011022 |
[Renal tolerance of selective inhibitors of cyclooxygenase type 2]. | Presse medicale (Paris, France : 1983) 20011020 |
Simultaneous quantification of arachidonic acid metabolites in cultured tumor cells using high-performance liquid chromatography/electrospray ionization tandem mass spectrometry. | Analytical biochemistry 20011015 |
Anaphylactoid reactions associated with menstruation affecting two sisters. | The Medical journal of Australia 20011015 |
COX-1 and COX-2 inhibitors. | Best practice & research. Clinical gastroenterology 20011001 |
COX-2 inhibition and prevention of cancer. | Best practice & research. Clinical gastroenterology 20011001 |
Uterine relaxant effects of cyclooxygenase-2 inhibitors in vitro. | Obstetrics and gynecology 20011001 |
Targeting angiogenic processes by combination rofecoxib and ionizing radiation. | American journal of clinical oncology 20011001 |
Characterization of the effects of antiangiogenic agents on tumor pathophysiology. | American journal of clinical oncology 20011001 |
Chronotherapy and chronotoxicity of the cyclooxygenase-2 inhibitor, celecoxib, in athymic mice bearing human breast cancer xenografts. | Clinical cancer research : an official journal of the American Association for Cancer Research 20011001 |
Degradation products of cyanidin glycosides from tart cherries and their bioactivities. | Journal of agricultural and food chemistry 20011001 |
Clinical implications of drug interactions with coxibs. | Pharmacotherapy 20011001 |
[Changes in ulcerogenic response to non-steroidal anti-inflammatory drugs (NSAIDs) in adjuvant arthritic rats]. | Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20011001 |
Nonsteroidal anti-inflammatory drugs for perioperative pain control. | Medicine and health, Rhode Island 20011001 |
Is concern about cardiovascular events with the new coxib class of drugs justified? | Medscape women's health 20011001 |
Stimulated release of arachidonic acid by agonists of the peroxisome proliferator-activated receptor and retinoic acid receptors. | Prostaglandins, leukotrienes, and essential fatty acids 20011001 |
Three-dimensional quantitative structure-activity relationships of cyclo-oxygenase-2 (COX-2) inhibitors: a comparative molecular field analysis. | Journal of medicinal chemistry 20010927 |
Determination of celecoxib in human plasma and rat microdialysis samples by liquid chromatography tandem mass spectrometry. | Journal of chromatography. B, Biomedical sciences and applications 20010925 |
[New study of selective COX-2 inhibitors. Protecting the stomach while risking the heart? (interview by Dr. Beate Schumacher)]. | MMW Fortschritte der Medizin 20010906 |
Pain relief at a price. A blow to the heart? | U.S. news & world report 20010903 |
Arthritis: what it is, why you get it and how to stop the pain. | Newsweek 20010903 |
How safe are your prescription pills? | Time 20010903 |
Role of inducible cyclooxygenase and prostaglandins in Clostridium difficile toxin A-induced secretion and inflammation in an animal model. | The Journal of infectious diseases 20010901 |
A review of cancer chemopreventive agents. | Current medicinal chemistry 20010901 |
Tolerability to new COX-2 inhibitors in NSAID-sensitive patients with cutaneous reactions. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20010901 |
[Cyclooxygenase (COX)-2 selective inhibitors: aspirin, a dual COX-1/COX-2 inhibitor, to COX-2 selective inhibitors]. | Nihon yakurigaku zasshi. Folia pharmacologica Japonica 20010901 |
A comparison of renal-related adverse drug reactions between rofecoxib and celecoxib, based on the World Health Organization/Uppsala Monitoring Centre safety database. | Clinical therapeutics 20010901 |
[Anaphylactic shock induced by celecoxib]. | Annales de medecine interne 20010901 |
[COX-2 inhibitor non-steroidal anti-inflammatory drugs, myth or reality?]. | Revue medicale de Bruxelles 20010901 |
Renocortical expression of renin and of cyclooxygenase-2 in response to angiotensin II AT1 receptor blockade is closely coordinated but not causally linked. | Pflugers Archiv : European journal of physiology 20010901 |
The growth of malignant keratinocytes depends on signaling through the PGE(2) receptor EP1. | Neoplasia (New York, N.Y.) 20010901 |
Drug interactions update: drugs, herbs, and oral anticoagulation. | Journal of thrombosis and thrombolysis 20010901 |
[Thinking about the specific cyclooxygenase-2 inhibitors since its recommendation]. | Zhonghua nei ke za zhi 20010901 |
Design and synthesis of 4,5-diphenyl-4-isoxazolines: novel inhibitors of cyclooxygenase-2 with analgesic and antiinflammatory activity. | Journal of medicinal chemistry 20010830 |
Design and synthesis of celecoxib and rofecoxib analogues as selective cyclooxygenase-2 (COX-2) inhibitors: replacement of sulfonamide and methylsulfonyl pharmacophores by an azido bioisostere. | Journal of medicinal chemistry 20010830 |
Selective and rapid liquid chromatography-mass spectrometry method for the quantification of rofecoxib in pharmacokinetic studies with humans. | Journal of chromatography. B, Biomedical sciences and applications 20010825 |
COX-2 inhibition and thrombotic tendency: a need for surveillance. | The Medical journal of Australia 20010820 |
[Coxibs: cyclooxygenase-2 inhibitors]. | Wiener klinische Wochenschrift 20010816 |
Effects of selective cyclooxygenase-2 inhibition on vascular responses and thrombosis in canine coronary arteries. | Circulation 20010814 |
Researchers deny any attempt to mislead the public over JAMA article on arthritis drug. | BMJ (Clinical research ed.) 20010811 |
The coxibs, selective inhibitors of cyclooxygenase-2. | The New England journal of medicine 20010809 |
A three-step kinetic mechanism for selective inhibition of cyclo-oxygenase-2 by diarylheterocyclic inhibitors. | The Biochemical journal 20010801 |
Celecoxib-induced Sweet's syndrome. | Journal of the American Academy of Dermatology 20010801 |
Familiar drugs may prevent cancer. | Postgraduate medical journal 20010801 |
Acute hepatocellular and cholestatic injury in a patient taking celecoxib. | Postgraduate medical journal 20010801 |
Effects of COX-2 inhibitors on aortic prostacyclin production in cholesterol-fed rabbits. | Atherosclerosis 20010801 |
Risk of cardiovascular events associated with selective COX-2 inhibitors. | JAMA 20010801 |
Visual disturbance associated with celecoxib--a comment. | Pharmacotherapy 20010801 |
New combination promising against colon cancer. | Expert review of anticancer therapy 20010801 |
[Safety of specific cyclo-oxygenase 2 inhibitors]. | Nederlands tijdschrift voor geneeskunde 20010728 |
Drug Points: Cholestatic hepatitis in association with celecoxib. | BMJ (Clinical research ed.) 20010707 |
Acute renal failure related to high-dose celecoxib. | Annals of internal medicine 20010703 |
Effect of cyclooxygenase-2 inhibitor (celecoxib) on the infarcted heart in situ. | Pharmacology 20010701 |
Comparative analysis of pharmacologic and/or genetic disruption of cyclooxygenase-1 and cyclooxygenase-2 function in female reproduction in mice. | Endocrinology 20010701 |
Celecoxib loses its anti-inflammatory efficacy at high doses through activation of NF-kappaB. | FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20010701 |
Chemoprevention of colorectal cancer. | Current opinion in oncology 20010701 |
Cyclooxygenase-selective inhibition of prostanoid formation: transducing biochemical selectivity into clinical read-outs. | The Journal of clinical investigation 20010701 |
Selective cyclooxygenase-2 inhibitors: a pattern of nephrotoxicity similar to traditional nonsteroidal anti-inflammatory drugs. | The American journal of medicine 20010701 |
A new class of COX-2 inhibitors offer an alternative to NSAIDS in pain management after spinal surgery. | Spine 20010701 |
Anaphylaxis to celecoxib. | Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology 20010701 |
Stimulated release of arachidonic acid from rat liver cells by celecoxib and indomethacin. | Prostaglandins, leukotrienes, and essential fatty acids 20010701 |
Cyclooxygenase (COX-2) selective inhibitors. Any better than NSAIDs? | Canadian family physician Medecin de famille canadien 20010701 |
Rationale for the observed COX-2/COX-1 selectivity of celecoxib from Monte Carlo simulations. | Bioorganic & medicinal chemistry letters 20010618 |
A stable prostacyclin analog enhances ectopic activity in rat sensory neurons following neuropathic injury. | Brain research 20010615 |
Cyclooxygenase-2 inhibition and renal function. | Annals of internal medicine 20010605 |
[Safety of specific cyclo-oxygenase 2 inhibitors]. | Nederlands tijdschrift voor geneeskunde 20010602 |
Rat colorectal tumours treated with a range of non-steroidal anti-inflammatory drugs show altered cyclooxygenase-2 and cyclooxygenase-1 splice variant mRNA expression levels. | Carcinogenesis 20010601 |
Targeting cyclooxygenase 2 and HER-2/neu pathways inhibits colorectal carcinoma growth. | Gastroenterology 20010601 |
Cyclooxygenase-1 vs. cyclooxygenase-2 inhibitors in the induction of antinociception in rodent withdrawal reflexes. | Neuropharmacology 20010601 |
Evaluation of the tocolytic effect of a selective cyclooxygenase-2 inhibitor in a mouse model of lipopolysaccharide-induced preterm delivery. | Molecular human reproduction 20010601 |
T-cell involvement in drug-induced acute generalized exanthematous pustulosis. | The Journal of clinical investigation 20010601 |
Cyclooxygenase-2: a target for the prevention and treatment of breast cancer. | Endocrine-related cancer 20010601 |
Possible celecoxib-induced gastroduodenal ulceration. | The Annals of pharmacotherapy 20010601 |
Suppression of occurrence and advancement of beta-catenin-accumulated crypts, possible premalignant lesions of colon cancer, by selective cyclooxygenase-2 inhibitor, celecoxib. | Japanese journal of cancer research : Gann 20010601 |
Celecoxib--the debate rages on. | South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20010601 |
Celecoxib-- the debate ranges on. | South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20010601 |
[Clinical application of cyclooxygenase-2 inhibitors]. | Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego 20010601 |
Celecoxib and rofecoxib: a distinction with a difference? | Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20010601 |
COX-2 specific inhibitors in the management of osteoarthritis of the knee: a placebo-controlled, randomized, double-blind study. | Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20010601 |
Non-steroidal anti-inflammatory drugs with activity against either cyclooxygenase 1 or cyclooxygenase 2 inhibit colorectal cancer in a DMH rodent model by inducing apoptosis and inhibiting cell proliferation. | Gut 20010501 |
Pharmacokinetics of celecoxib after oral administration in dogs and humans: effect of food and site of absorption. | The Journal of pharmacology and experimental therapeutics 20010501 |
Surveillance colonoscopy or chemoprevention with COX-2 inhibitors in average-risk post-polypectomy patients: a decision analysis. | Alimentary pharmacology & therapeutics 20010501 |
EULAR recommendations for the management of knee osteoarthritis. | Annals of the rheumatic diseases 20010501 |
Cyclooxygenase 2 inhibitors and thrombogenicity production: comment on the article by Crofford et al. | Arthritis and rheumatism 20010501 |
Osteoarthritis. A primary care approach for physicians in 2000 and beyond. | Saudi medical journal 20010501 |
Preventing gastrointestinal complications of NSAIDs. Risk factors, recent advances, and latest strategies. | Postgraduate medicine 20010501 |
Current concepts regarding pharmacologic treatment of rheumatoid and osteoarthritis. | Hand clinics 20010501 |
NSAIDS and selective COX-2 inhibitors: competition between gastroprotection and cardioprotection. | Lancet (London, England) 20010421 |
Renal safety of combined cyclooxygenase 2 (COX-2) inhibitor and angiotensin II receptor blocker administration in mild volume depletion. | Swiss medical weekly 20010407 |
Liquid chromatographic-mass spectrometric determination of celecoxib in plasma using single-ion monitoring and its use in clinical pharmacokinetics. | Journal of chromatography. B, Biomedical sciences and applications 20010405 |
COX-2 inhibitors. | The Medical journal of Australia 20010402 |
COX-2 inhibitors and the gastrointestinal tract. | Gut 20010401 |
Substrate inhibition kinetics for cytochrome P450-catalyzed reactions. | Drug metabolism and disposition: the biological fate of chemicals 20010401 |
LC separation of ortho and meta isomers of celecoxib in bulk and formulations using a chiral column. | Journal of pharmaceutical and biomedical analysis 20010401 |
Middermal elastolysis in two patients with lupus erythematosus. | The American Journal of dermatopathology 20010401 |
Proapoptotic anti-inflammatory drugs. | Urology 20010401 |
Trial endpoints for drug approval in oncology: Chemoprevention. | Urology 20010401 |
Selective COX-2 inhibitors. | The American journal of nursing 20010401 |
Celecoxib and rofecoxib. The role of COX-2 inhibitors in dental practice. | Journal of the American Dental Association (1939) 20010401 |
Cyclooxygenase 2 inhibition and thrombosis: comment on the article by Crofford et al. | Arthritis and rheumatism 20010401 |
Evidence for a direct role of cyclo-oxygenase 2 in implant wear debris-induced osteolysis. | Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 20010401 |
Reduced incidence of gastroduodenal ulcers with celecoxib, a novel cyclooxygenase-2 inhibitor, compared to naproxen in patients with arthritis. | The American journal of gastroenterology 20010401 |
Exacerbation of inflammatory bowel disease associated with use of celecoxib. | The American journal of gastroenterology 20010401 |
Gastrointestinal damage induced by celecoxib and rofecoxib in rats. | Digestive diseases and sciences 20010401 |
In-vitro metabolism of celecoxib, a cyclooxygenase-2 inhibitor, by allelic variant forms of human liver microsomal cytochrome P450 2C9: correlation with CYP2C9 genotype and in-vivo pharmacokinetics. | Pharmacogenetics 20010401 |
[Effect of celecoxib, a COX-2 inhibitor, in familial adenomatous polyposis]. | Zeitschrift fur Gastroenterologie 20010401 |
Inhibition of cyclooxygenase-1 or -2 on insulin sensitivity in healthy subjects. | Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme 20010401 |
[The coxibs, third generation anti-inflammatories]. | Revue medicale de Bruxelles 20010401 |
Celecoxib--the debate rages on. | South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20010401 |
[COX-2 specific inhibitors: are NSAIDs and the stomach become reconcilied?]. | Gastroenterologie clinique et biologique 20010401 |
Celecoxib in osteoarthritis and rheumatoid arthritis: new preparation. As disappointing as rofecoxib. | Prescrire international 20010401 |
Selective inhibitors of cyclooxygenase-2: a growing class of anti-inflammatory drugs. | Molecular interventions 20010401 |
COX-2 inhibitors and the kidney. | Hospital practice (1995) 20010315 |
Where is the evidence that cyclooxygenase inhibition is the primary cause of nonsteroidal anti-inflammatory drug (NSAID)-induced gastrointestinal injury? Topical injury revisited. | Biochemical pharmacology 20010315 |
Functional status and health-related quality of life of elderly osteoarthritic patients treated with celecoxib. | The journals of gerontology. Series A, Biological sciences and medical sciences 20010301 |
[64th Congress of the American College of Rheumatology, Philadelphia, October 28-November 2, 2000]. | La Revue de medecine interne 20010301 |
[Therapy with preferential and specific COX-2 inhibitors]. | Der Internist 20010301 |
COX-2 inhibition in clinical cancer prevention. | Oncology (Williston Park, N.Y.) 20010301 |
Osteoarthritis management: the role of cyclooxygenase-2-selective inhibitors. | Clinical therapeutics 20010301 |
Discovery and design of selective cyclooxygenase-2 inhibitors as non-ulcerogenic, anti-inflammatory drugs with potential utility as anti-cancer agents. | Current drug targets 20010301 |
Cyclo-oxygenase 2 inhibitors: an important new drug classification. | Pain management nursing : official journal of the American Society of Pain Management Nurses 20010301 |
Efficacy of cyclooxygenase-2-specific inhibitors. | The American journal of medicine 20010219 |
Gastrointestinal toxic side effects of nonsteroidal anti-inflammatory drugs and cyclooxygenase-2-specific inhibitors. | The American journal of medicine 20010219 |
FDA refuses companies' request to drop ulcer warning. | BMJ (Clinical research ed.) 20010217 |
Celecoxib-induced cholestatic hepatitis. | Annals of internal medicine 20010206 |
Etoricoxib (MK-0663): preclinical profile and comparison with other agents that selectively inhibit cyclooxygenase-2. | The Journal of pharmacology and experimental therapeutics 20010201 |
COX-2 inhibitors in rheumatoid arthritis. | Current rheumatology reports 20010201 |
Successful use of cyclooxygenase-2 inhibitor in a patient with aspirin-induced asthma. | Southern medical journal 20010201 |
Comparison of once-daily and twice-daily administration of celecoxib for the treatment of osteoarthritis of the knee. | Clinical therapeutics 20010201 |
Efficacy and tolerability of celecoxib versus hydrocodone/acetaminophen in the treatment of pain after ambulatory orthopedic surgery in adults. | Clinical therapeutics 20010201 |
Synthesis and SAR of a new series of COX-2-selective inhibitors: pyrazolo[1,5-a]pyrimidines. | Journal of medicinal chemistry 20010201 |
COX-2 inhibitors: new drugs for the management of pain and inflammation. | Dentistry today 20010201 |
Celecoxib in patients with asthma and aspirin intolerance. The Celecoxib in Aspirin-Intolerant Asthma Study Group. | The New England journal of medicine 20010111 |
Acute upregulation of COX-2 by renal artery stenosis. | American journal of physiology. Renal physiology 20010101 |
Hyaluronan-induced cyclooxygenase-2 expression promotes thromboxane A2 production by renal cells. | Kidney international 20010101 |
Colorectal cancer chemoprevention: biochemical targets and clinical development of promising agents. | European journal of cancer (Oxford, England : 1990) 20010101 |
Visual disturbance associated with celecoxib. | Pharmacotherapy 20010101 |
Efficacy of celecoxib, a cyclooxygenase 2-specific inhibitor, in the treatment of ankylosing spondylitis: a six-week controlled study with comparison against placebo and against a conventional nonsteroidal antiinflammatory drug. | Arthritis and rheumatism 20010101 |
Celecoxib--a rational alternative to NSAIDs. | South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20010101 |
Breast cancer chemoprevention: beyond tamoxifen. | Breast cancer research : BCR 20010101 |
Celecoxib versus diclofenac in the management of osteoarthritis of the knee. | Scandinavian journal of rheumatology 20010101 |
[Pharma-clinics. The drug of the month. Celecoxib (Celebrex)]. | Revue medicale de Liege 20010101 |
Effect of the cyclooxygenase-2 inhibitor celecoxib on bronchial responsiveness and cough reflex sensitivity in asthmatics. | Pulmonary pharmacology & therapeutics 20010101 |
Renal effects of COX-2-selective inhibitors. | American journal of nephrology 20010101 |
A framework for evaluating the clinical consequences of initial therapy with NSAIDs, NSAIDs plus gastroprotective agents, or celecoxib in the treatment of arthritis. | PharmacoEconomics 20010101 |
An economic model for determining the costs and consequences of using various treatment alternatives for the management of arthritis in Canada. | PharmacoEconomics 20010101 |
Economic evaluation of celecoxib, a new cyclo-oxygenase 2 specific inhibitor, in Switzerland. | PharmacoEconomics 20010101 |
Pharmacokinetics of celecoxib in the presence and absence of interferon-induced acute inflammation in the rat: application of a novel HPLC assay. | Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques 20010101 |
Cardiovascular and renal effects of COX-2-specific inhibitors: recent insights and evolving clinical implications. | American journal of therapeutics 20010101 |
Cyclooxygenase-2--specific inhibitors and cardiorenal function: a randomized, controlled trial of celecoxib and rofecoxib in older hypertensive osteoarthritis patients. | American journal of therapeutics 20010101 |
Cyclooxygenase-2 pathway correlates with VEGF expression in head and neck cancer. Implications for tumor angiogenesis and metastasis. | Neoplasia (New York, N.Y.) 20010101 |
Should celecoxib be contraindicated in patients who are allergic to sulfonamides? Revisiting the meaning of 'sulfa' allergy. | Drug safety 20010101 |
Anti-inflammatory drugs, cyclooxygenases and other factors. | Expert opinion on pharmacotherapy 20010101 |
Celecoxib: a new option in the treatment of arthropathies and familial adenomatous polyposis. | Expert opinion on pharmacotherapy 20010101 |
Apoptosis signaling pathways mediated by cyclooxygenase-2 inhibitors in prostate cancer cells. | Advances in enzyme regulation 20010101 |
Rofecoxib: a review of its use in the management of osteoarthritis, acute pain and rheumatoid arthritis. | Drugs 20010101 |
Alzheimer's disease, inflammation and non-steroidal anti-inflammatory drugs. | Bratislavske lekarske listy 20010101 |
Potential adverse effects of cyclooxygenase-2 inhibition: evidence from animal models of inflammation. | BioDrugs : clinical immunotherapeutics, biopharmaceuticals and gene therapy 20010101 |
Celecoxib- and rofecoxib-induced delirium. | The Journal of neuropsychiatry and clinical neurosciences 20010101 |
[Selective cyclooxygenase 2 inhibitors (COX-2)]. | Postepy higieny i medycyny doswiadczalnej 20010101 |
Cyclooxygenase inhibitors: any reservations? | Internal medicine journal 20010101 |
Upper gastroduodenal ulceration in arthritis patients treated with celecoxib. | The Annals of pharmacotherapy 20010101 |
[Celecoxib]. | Revista de medicina de la Universidad de Navarra 20010101 |
[The coxibs, third generation of non-steroidal anti-inflammatory agents]. | Journal de pharmacie de Belgique 20010101 |
[Role of cyclooxygenase-2 (COG-2) in the etiology of pain]. | Terapevticheskii arkhiv 20010101 |
[Celebrex: confirmed effectiveness and safety (new data)]. | Terapevticheskii arkhiv 20010101 |
[Effectiveness and tolerance of celebrex in osteoarthrosis (data of a Russian study)]. | Terapevticheskii arkhiv 20010101 |
[Gastroduodenal tolerance of celecoxib (celebrex) in patients with osteoarthrosis: an endoscopic evaluation]. | Terapevticheskii arkhiv 20010101 |
[Clinical use of COX-2 inhibitors]. | Vojnosanitetski pregled 20010101 |
The ever-emerging anti-inflammatories. Have there been any real advances? | Journal of physiology, Paris 20010101 |
NSAIDs inhibit the activation of egr-1 gene in microvascular endothelial cells. A key to inhibition of angiogenesis? | Journal of physiology, Paris 20010101 |
What have we learned from the large outcomes trials of COX-2 selective inhibitors? The rheumatologist's perspective. | Clinical and experimental rheumatology 20010101 |
COX-2 inhibitors and the cardiovascular system. | Clinical and experimental rheumatology 20010101 |
Analgesia and COX-2 inhibition. | Clinical and experimental rheumatology 20010101 |
A cyclooxygenase-2 inhibitor impairs ligament healing in the rat. | The American journal of sports medicine 20010101 |
Approach to angiogenesis inhibition based on cyclooxygenase-2. | Cancer journal (Sudbury, Mass.) 20010101 |
Participation of COX, IL-1 beta and TNF alpha in formalin-induced inflammatory pain. | Proceedings of the Western Pharmacology Society 20010101 |
Comparative efficacy and safety of celecoxib and naproxen in the treatment of osteoarthritis of the hip. | The Journal of international medical research 20010101 |
Dose-response effects of the COX-2 inhibitor, celecoxib, on the chemoprevention of mammary carcinogenesis. | Anticancer research 20010101 |
[Specific inhibitors of cyclooxygenase-2 (COX-2): current knowledge and perspectives]. | Acta bio-medica de L'Ateneo parmense : organo della Societa di medicina e scienze naturali di Parma 20010101 |
Identification of sulfonamide-like adverse drug reactions to celecoxib in the World Health Organization database. | Current medical research and opinion 20010101 |
Effect of cyclooxygenase and NO synthase inhibitors on antinociceptive action of acetaminophen. | Polish journal of pharmacology 20010101 |
An update on specific COX-2 inhibitors: the COXIBs. | Bulletin on the rheumatic diseases 20010101 |
[Celecoxib]. | Reumatizam 20010101 |
Celecoxib. | Dimensions of critical care nursing : DCCN 20010101 |
Non-steroidal anti-inflammatory drugs with different cyclooxygenase inhibitory profiles that prevent aberrant crypt foci formation but vary in acute gastrotoxicity in a rat model. | Journal of gastroenterology and hepatology 20001201 |
Gastrointestinal toxicity with celecoxib vs nonsteroidal anti-inflammatory drugs for osteoarthritis and rheumatoid arthritis: the CLASS study: A randomized controlled trial. Celecoxib Long-term Arthritis Safety Study. | JAMA 20000913 |
Acute onset of auditory hallucinations after initiation of celecoxib therapy. | The American journal of psychiatry 20000601 |
Novel antiarthritic agents with 1,2-isothiazolidine-1,1-dioxide (gamma-sultam) skeleton: cytokine suppressive dual inhibitors of cyclooxygenase-2 and 5-lipoxygenase. | Journal of medicinal chemistry 20000518 |
The cyclooxygenase-2 inhibitor celecoxib induces apoptosis by blocking Akt activation in human prostate cancer cells independently of Bcl-2. | The Journal of biological chemistry 20000414 |
Selective cyclo-oxygenase-2 inhibition with celecoxib elevates blood pressure and promotes leukocyte adherence. | British journal of pharmacology 20000401 |
4-[5-Methyl-3-phenylisoxazol-4-yl]- benzenesulfonamide, valdecoxib: a potent and selective inhibitor of COX-2. | Journal of medicinal chemistry 20000309 |
Cyclooxygenase-2 selective inhibitors aggravate kainic acid induced seizure and neuronal cell death in the hippocampus. | Brain research 19991002 |