Home Sulfos 4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide

4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide

CAS No.:
122-11-2
Catalog Number:
AG00HGKI
Molecular Formula:
C12H14N4O4S
Molecular Weight:
310.3290
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5g
98%
In Stock USA
United States
$19
- +
25g
98%
In Stock USA
United States
$50
- +
100g
98%
In Stock USA
United States
$150
- +
500g
98%
In Stock USA
United States
$525
- +
Product Description
Catalog Number:
AG00HGKI
Chemical Name:
4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzene-1-sulfonamide
CAS Number:
122-11-2
Molecular Formula:
C12H14N4O4S
Molecular Weight:
310.3290
MDL Number:
MFCD00057345
IUPAC Name:
4-amino-N-(2,6-dimethoxypyrimidin-4-yl)benzenesulfonamide
InChI:
InChI=1S/C12H14N4O4S/c1-19-11-7-10(14-12(15-11)20-2)16-21(17,18)9-5-3-8(13)4-6-9/h3-7H,13H2,1-2H3,(H,14,15,16)
InChI Key:
ZZORFUFYDOWNEF-UHFFFAOYSA-N
SMILES:
COc1nc(OC)nc(c1)NS(=O)(=O)c1ccc(cc1)N
EC Number:
204-523-7
UNII:
30CPC5LDEX
Properties
Complexity:
420  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
310.074g/mol
Formal Charge:
0
Heavy Atom Count:
21  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Isotope Atom Count:
0
Molecular Weight:
310.328g/mol
Monoisotopic Mass:
310.074g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
125A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
1.6  
Literature
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Pharmacokinetics of sulfadimethoxine and ormetoprim in a 5:1 ratio following intraperitoneal and oral administration, in the hybrid striped bass (Morone chrysops x Morone saxitalis). Journal of veterinary pharmacology and therapeutics 20040201
Acute columnaris infection in channel catfish, Ictalurus punctatus (Rafinesque): efficacy of practical treatments for warmwater aquaculture ponds. Journal of fish diseases 20040101
Sequential analysis of development of invasive thyroid follicular cell carcinomas in inflamed capsular regions of rats treated with sulfadimethoxine after N-bis(2-hydroxypropyl)nitrosamine-initiation. Toxicologic pathology 20040101
Specificity of co-promoting effects of caffeine on thyroid carcinogenesis in rats pretreated with N-bis(2-hydroxypropyl)nitrosamine. Toxicologic pathology 20040101
Sorption of sulfonamide pharmaceutical antibiotics on whole soils and particle-size fractions. Journal of environmental quality 20040101
pH-dependent elution profiles of selected proteins in HPLC having a stationary phase modified with pH-sensitive sulfonamide polymers. Journal of biomaterials science. Polymer edition 20040101
Determination of sulfonamide residues in the tissues of food animals using automated precolumn derivatization and liquid chromatography with fluorescence detection. Journal of AOAC International 20040101
Pharmacokinetics of quinacrine in the treatment of prion disease. BMC infectious diseases 20040101
Effects of sodium chlorate on antibiotic resistance in Escherichia coli O157:H7. Foodborne pathogens and disease 20040101
Determination of some sulfonamides and trimethoprim in chicken, fish muscle and eggs by liquid chromatography-tandem mass spectrometry. Veterinaria italiana 20040101
Liquid chromatography-fluorescence detection for simultaneous analysis of sulfonamide residues in honey. Analytical and bioanalytical chemistry 20030601
Disposition of sulfadimethoxine in male llamas (Llama glama) after single intravenous and oral administrations. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20030301
A national surveillance of antimicrobial resistance in Escherichia coli isolated from food-producing animals in Japan. The Journal of antimicrobial chemotherapy 20030201
Characterization of a Cu(II) complex of sulfadimethoxine. Journal of inorganic biochemistry 20030201
Resistance of bacterial isolates from poultry products to therapeutic veterinary antibiotics. Journal of food protection 20030101
Survey of residual tetracycline antibiotics and sulfa drugs in kidneys of diseased animals in the Aichi Prefecture, Japan (1995-1999). Journal of AOAC International 20030101
Somatosensory and brainstem auditory evoked potentials in the Gunn rat model of acute bilirubin neurotoxicity. Pediatric research 20021201
Penetration of drug resistance in Escherichia coli isolated from laboratory animals. The Journal of veterinary medical science 20021201
Efficacy of oral sulfadimethoxine against two gregarine parasites, Protomagalhaensia granulosae and Gregarina cubensis (Apicomplexa: Eugregarinida), infecting the Death's Head cockroach, Blaberus discoidalis. The Journal of parasitology 20020801
Comparison of ion-pairing and ion-suppressing liquid chromatographic methods for the determination of pyrimethamine and ormetoprim in chicken feed. Journal of chromatographic science 20020701
Sulphadimethoxine and Azolla filiculoides Lam.: a model for drug remediation. Water research 20020701
Self-assembled hydrogel nanoparticles responsive to tumor extracellular pH from pullulan derivative/sulfonamide conjugate: characterization, aggregation, and adriamycin release in vitro. Pharmaceutical research 20020501
Improvement of a two-stage carcinogenesis model to detect modifying effects of endocrine disrupting chemicals on thyroid carcinogenesis in rats. Cancer letters 20020408
Quantification of veterinary antibiotics (sulfonamides and trimethoprim) in animal manure by liquid chromatography-mass spectrometry. Journal of chromatography. A 20020405
Sulphonamide residues in eggs following drug administration via the drinking water. Food additives and contaminants 20020401
Sulfadimethoxine and rhodamine B as oral biomarkers for European badgers (Meles meles). Journal of wildlife diseases 20020401
Antibiotic susceptibility patterns for environmental streptococci isolated from bovine mastitis in central California dairies. Journal of dairy science 20020101
Determination of sulfonamide residues in eggs by liquid chromatography. Journal of AOAC International 20020101
Quantitative determination of sulfonamide in meat by liquid chromatography-electrospray-mass spectrometry. Talanta 20011224
Effect of hypothermia on bilirubin-induced alterations in brain cell membrane function and energy metabolism in newborn piglets. Brain research 20011220
Matrix solid-phase dispersion extraction and high-performance liquid chromatographic determination of residual sulfonamides in chicken. Journal of chromatography. A 20011207
Transference of dietary veterinary drugs into eggs. Veterinary research communications 20011201
High-performance liquid chromatographic procedure for routine residue monitoring of seven sulfonamides in milk. Fresenius' journal of analytical chemistry 20011201
Disposition of sulfadimethoxine in camels (Camelus dromedarius) following single intravenous and oral doses. Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians 20011201
Pharmacokinetics of sulfadimethoxine and sulfamethoxazole in combination with trimethoprim after oral single- and multiple-dose administration to healthy pigs. Veterinary research communications 20010801
Synergistic effects of high-dose soybean intake with iodine deficiency, but not sulfadimethoxine or phenobarbital, on rat thyroid proliferation. Japanese journal of cancer research : Gann 20010401
In vitro hepatobiotransformation of sulphadimethoxine in laying hens. Journal of veterinary medicine. A, Physiology, pathology, clinical medicine 20010401
Antimicrobial susceptibilities of Erysipelothrix rhusiopathiae isolated from pigs with swine erysipelas in Japan, 1988-1998. Journal of veterinary medicine. B, Infectious diseases and veterinary public health 20010301
Efficacy of 101 antimicrobials and other agents on the development of Cryptosporidium parvum in vitro. Annals of tropical medicine and parasitology 19961201
Monodrug efficacies of sulfonamides in prophylaxis for Pneumocystis carinii pneumonia. Antimicrobial agents and chemotherapy 19960401
[Modifying effects of goitrogens on the tumor development in the liver and lung of rats]. Eisei Shikenjo hokoku. Bulletin of National Institute of Hygienic Sciences 19960101
Inhibition of recombinant Pneumocystis carinii dihydropteroate synthetase by sulfa drugs. Antimicrobial agents and chemotherapy 19950801
Assessment of candidate anticryptosporidial agents in an immunosuppressed rat model. The Journal of infectious diseases 19930301
Activity of sulfadimethoxine against cryptosporidiosis in dairy calves. The Journal of parasitology 19920601
Anticryptosporidial activity is associated with specific sulfonamides in immunosuppressed rats. The Journal of parasitology 19910401
Anti-cryptosporidial drug activity screened with an immunosuppressed rat model. The Journal of protozoology 19910101
Drugs as allergens: detection and combining site specificities of IgE antibodies to sulfamethoxazole. Molecular immunology 19881201
[Noncholinesterase component in the molecular mechanism of action of the cholinesterase reactivator dipyroxime]. Biulleten' eksperimental'noi biologii i meditsiny 19820601
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