GW 6471
| Title | Journal |
|---|---|
| Activation of peroxisome proliferator-activated receptor α ameliorates perfluorododecanoic acid-induced production of reactive oxygen species in rat liver. | Archives of toxicology 20160601 |
| Inhibition of PPARα attenuates vimentin phosphorylation on Ser-83 and collapse of vimentin filaments during exposure of rat Sertoli cells in vitro to DBP. | Reproductive toxicology (Elmsford, N.Y.) 20141201 |
| Sargahydroquinoic acid inhibits TNFα-induced AP-1 and NF-κB signaling in HaCaT cells through PPARα activation. | Biochemical and biophysical research communications 20140808 |
| Fenofibrate suppresses melanogenesis in B16-F10 melanoma cells via activation of the p38 mitogen-activated protein kinase pathway. | Chemico-biological interactions 20131005 |
| SIRT1 inhibits NADPH oxidase activation and protects endothelial function in the rat aorta: implications for vascular aging. | Biochemical pharmacology 20130501 |
| Pretreatment with proteasome inhibitors protects against oxidative injuries via PPARα-dependent and -independent pathways in ARPE-19 cells. | Investigative ophthalmology & visual science 20120831 |
| Alteration of neuropathic and visceral pain in female C57BL/6J mice lacking the PPAR-α gene. | Psychopharmacology 20120801 |
| The synthetic cannabinoid R(+)WIN55,212-2 augments interferon-β expression via peroxisome proliferator-activated receptor-α. | The Journal of biological chemistry 20120720 |
| Effects of palmitoylethanolamide on aqueous humor outflow. | Investigative ophthalmology & visual science 20120701 |
| Effects of the anandamide uptake blocker AM404 on food intake depend on feeding status and route of administration. | Pharmacology, biochemistry, and behavior 20120301 |
| OxLDL up-regulates Niemann-Pick type C1 expression through ERK1/2/COX-2/PPARα-signaling pathway in macrophages. | Acta biochimica et biophysica Sinica 20120201 |
| Peroxisome proliferator-activated receptor activity is involved in the osteoblastic differentiation regulated by bone morphogenetic proteins and tumor necrosis factor-α. | Molecular and cellular endocrinology 20120102 |
| Chemical cross-linking and high-resolution mass spectrometry to study protein-drug interactions. | Methods in molecular biology (Clifton, N.J.) 20120101 |
| Fenofibrate down-regulates renal OCT2-mediated organic cation transport via PPARα-independent pathways. | Drug metabolism and pharmacokinetics 20120101 |
| The role of PPARα in metformin-induced attenuation of mitochondrial dysfunction in acute cardiac ischemia/reperfusion in rats. | International journal of molecular sciences 20120101 |
| Fenofibrate suppresses growth of the human hepatocellular carcinoma cell via PPARα-independent mechanisms. | European journal of cell biology 20110801 |
| Regulation mechanism of ABCA1 expression by statins in hepatocytes. | European journal of pharmacology 20110715 |
| Activation of peroxisome proliferator-activated receptor-alpha stimulates both differentiation and fatty acid oxidation in adipocytes. | Journal of lipid research 20110501 |
| Activation of peroxisome-proliferator-activated receptors α and γ mediates remote ischemic preconditioning against myocardial infarction in vivo. | Experimental biology and medicine (Maywood, N.J.) 20110101 |
| Brown adipose tissue responds to cold and adrenergic stimulation by induction of FGF21. | Molecular medicine (Cambridge, Mass.) 20110101 |
| 13-hydroxy linoleic acid increases expression of the cholesterol transporters ABCA1, ABCG1 and SR-BI and stimulates apoA-I-dependent cholesterol efflux in RAW264.7 macrophages. | Lipids in health and disease 20110101 |
| Leptin induces hypertrophy through activating the peroxisome proliferator-activated receptor α pathway in cultured neonatal rat cardiomyocytes. | Clinical and experimental pharmacology & physiology 20101101 |
| Adiponectin-mediated heme oxygenase-1 induction protects against iron-induced liver injury via a PPARα dependent mechanism. | The American journal of pathology 20101001 |
| Activation of peroxisome proliferator-activated receptor-beta/delta attenuates myocardial ischemia/reperfusion injury in the rat. | Shock (Augusta, Ga.) 20100801 |
| Fenofibrate induces effective apoptosis in mantle cell lymphoma by inhibiting the TNFalpha/NF-kappaB signaling axis. | Leukemia 20100801 |
| Resveratrol prevents the impairment of advanced glycosylation end products (AGE) on macrophage lipid homeostasis by suppressing the receptor for AGE via peroxisome proliferator-activated receptor gamma activation. | International journal of molecular medicine 20100501 |
| An innovative method to study target protein-drug interactions by mass spectrometry. | Journal of medicinal chemistry 20090514 |
| Inhibition of fatty acid amide hydrolase produces PPAR-alpha-mediated analgesia in a rat model of inflammatory pain. | British journal of pharmacology 20081201 |
| Exposure to perfluorooctane sulfonate or fenofibrate causes PPAR-alpha dependent transcriptional responses in chicken embryo hepatocytes. | Comparative biochemistry and physiology. Toxicology & pharmacology : CBP 20080801 |
| Inhibition of fatty acid amide hydrolase and cyclooxygenase-2 increases levels of endocannabinoid related molecules and produces analgesia via peroxisome proliferator-activated receptor-alpha in a model of inflammatory pain. | Neuropharmacology 20080701 |
| Time-dependence of cardiomyocyte differentiation disturbed by peroxisome proliferator-activated receptor alpha inhibitor GW6471 in murine embryonic stem cells in vitro. | Acta pharmacologica Sinica 20070501 |
| Fatty acid homeostasis and induction of lipid regulatory genes in skeletal muscles of peroxisome proliferator-activated receptor (PPAR) alpha knock-out mice. Evidence for compensatory regulation by PPAR delta. | The Journal of biological chemistry 20020719 |
| Structural basis for antagonist-mediated recruitment of nuclear co-repressors by PPARalpha. | Nature 20020214 |