Gsk1016790a
| Title | Journal |
|---|---|
| Activation of TRPV3 by Wood Smoke Particles and Roles in Pneumotoxicity. | Chemical research in toxicology 20180521 |
| A novel TRPV4-specific agonist inhibits monocyte adhesion and atherosclerosis. | Oncotarget 20160621 |
| Identification of potent Yes1 kinase inhibitors using a library screening approach. | Bioorganic & medicinal chemistry letters 20130801 |
| Optical recording reveals novel properties of GSK1016790A-induced vanilloid transient receptor potential channel TRPV4 activity in primary human endothelial cells. | Molecular pharmacology 20120901 |
| TRPV4 in porcine lens epithelium regulates hemichannel-mediated ATP release and Na-K-ATPase activity. | American journal of physiology. Cell physiology 20120615 |
| Elementary Ca2+ signals through endothelial TRPV4 channels regulate vascular function. | Science (New York, N.Y.) 20120504 |
| Hypotonicity-induced TRPV4 function in renal collecting duct cells: modulation by progressive cross-talk with Ca2+-activated K+ channels. | Cell calcium 20120201 |
| Effects of TRPV4 cation channel activation on the primary bladder afferent activities of the rat. | Neurourology and urodynamics 20120101 |
| Characterization of transient receptor potential vanilloid channel 4 (TRPV4) in human corneal endothelial cells. | Experimental eye research 20111101 |
| Mutations in TRPV4 cause an inherited arthropathy of hands and feet. | Nature genetics 20111002 |
| Transient receptor potential vanilloid 4 (TRPV4)-dependent calcium influx and ATP release in mouse oesophageal keratinocytes. | The Journal of physiology 20110715 |
| The polymodal ion channel transient receptor potential vanilloid 4 modulates calcium flux, spiking rate, and apoptosis of mouse retinal ganglion cells. | The Journal of neuroscience : the official journal of the Society for Neuroscience 20110511 |
| Determinants of TRPV4 activity following selective activation by small molecule agonist GSK1016790A. | PloS one 20110101 |
| Inhibition of the cation channel TRPV4 improves bladder function in mice and rats with cyclophosphamide-induced cystitis. | Proceedings of the National Academy of Sciences of the United States of America 20101102 |
| Activation of Trpv4 reduces the hyperproliferative phenotype of cystic cholangiocytes from an animal model of ARPKD. | Gastroenterology 20100701 |
| TRPV4-mediated endothelial Ca2+ influx and vasodilation in response to shear stress. | American journal of physiology. Heart and circulatory physiology 20100201 |
| Functional TRPV4 channels and an absence of capsaicin-evoked currents in freshly-isolated, guinea-pig urothelial cells. | Channels (Austin, Tex.) 20090101 |
| N-((1S)-1-{[4-((2S)-2-{[(2,4-dichlorophenyl)sulfonyl]amino}-3-hydroxypropanoyl)-1-piperazinyl]carbonyl}-3-methylbutyl)-1-benzothiophene-2-carboxamide (GSK1016790A), a novel and potent transient receptor potential vanilloid 4 channel agonist induces urinary bladder contraction and hyperactivity: Part I. | The Journal of pharmacology and experimental therapeutics 20080801 |
| Systemic activation of the transient receptor potential vanilloid subtype 4 channel causes endothelial failure and circulatory collapse: Part 2. | The Journal of pharmacology and experimental therapeutics 20080801 |