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TAME

CAS No.:
901-47-3
Catalog Number:
AG00GU6O
Molecular Formula:
C14H22N4O4S
Molecular Weight:
342.4139
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
50mg
99%
1 week
United States
$132
- +
100mg
99%
1 week
United States
$190
- +
Product Description
Catalog Number:
AG00GU6O
Chemical Name:
TAME
CAS Number:
901-47-3
Molecular Formula:
C14H22N4O4S
Molecular Weight:
342.4139
MDL Number:
MFCD01320524
IUPAC Name:
methyl (2S)-5-(diaminomethylideneamino)-2-[(4-methylphenyl)sulfonylamino]pentanoate
InChI:
InChI=1S/C14H22N4O4S/c1-10-5-7-11(8-6-10)23(20,21)18-12(13(19)22-2)4-3-9-17-14(15)16/h5-8,12,18H,3-4,9H2,1-2H3,(H4,15,16,17)/t12-/m0/s1
InChI Key:
FKMJXALNHKIDOD-LBPRGKRZSA-N
SMILES:
COC(=O)[C@@H](NS(=O)(=O)c1ccc(cc1)C)CCCNC(=N)N
UNII:
1H7BKF44U1
UN Number:
3271
Properties
Complexity:
503  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
0
Exact Mass:
342.136g/mol
Formal Charge:
0
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
342.414g/mol
Monoisotopic Mass:
342.136g/mol
Rotatable Bond Count:
9  
Topological Polar Surface Area:
145A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
0.4  
Literature
Title Journal
TA-2, a thrombin-like enzyme from the Chinese white-lipped green pitviper (Trimeresurus albolabris): isolation, biochemical and biological characterization. Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 20120701
Critical evaluation of the 2D-CSIA scheme for distinguishing fuel oxygenate degradation reaction mechanisms. Environmental science & technology 20120501
An APC/C inhibitor stabilizes cyclin B1 by prematurely terminating ubiquitination. Nature chemical biology 20120401
Vinyl functionalized silica hybrid monolith-based trypsin microreactor for on line digestion and separation via thiol-ene 'click' strategy. Journal of chromatography. A 20111104
Urinary methyl tert-butyl ether and benzene as biomarkers of exposure to urban traffic. Environment international 20110201
A new chymotrypsin-like serine protease involved in dietary protein digestion in a primitive animal, Scorpio maurus: purification and biochemical characterization. Lipids in health and disease 20110101
Simple preparation of pacific cod trypsin for enzymatic Peptide synthesis. Journal of amino acids 20110101
Pharmacologic inhibition of the anaphase-promoting complex induces a spindle checkpoint-dependent mitotic arrest in the absence of spindle damage. Cancer cell 20101019
Biochemical properties of anionic trypsin acting at high concentration of NaCl purified from the intestine of a carnivorous fish: smooth hound (Mustelus mustelus). Journal of agricultural and food chemistry 20100512
Protein targets of inflammatory serine proteases and cardiovascular disease. Journal of inflammation (London, England) 20100101
Thrombin a-chain: activation remnant or allosteric effector? Thrombosis 20100101
Comparison of sea snake (Hydrophiidae) neurotoxin to cobra (Naja) neurotoxin. Toxins 20091201
Isolation and chemical characterization of a toxin isolated from the venom of the sea snake, Hydrophis torquatus aagardi. Toxins 20091201
Trypsin from the pyloric ceca of pectoral rattail (Coryphaenoides pectoralis): purification and characterization. Journal of agricultural and food chemistry 20090812
Odour and flavour thresholds of gasoline additives (MTBE, ETBE and TAME) and their occurrence in Dutch drinking water collection areas. Chemosphere 20090701
Identification, purification, and characterization of a secretory serine protease in an Indian strain of Leishmania donovani. Molecular and cellular biochemistry 20090101
A novel serine protease from the snake venom of Agkistrodon blomhoffii ussurensis. Toxicon : official journal of the International Society on Toxinology 20081201
Study of fuel oxygenates solubility in aqueous media as a function of temperature and tert-butyl alcohol concentration. Chemosphere 20080501
Differential effects of Mg(ii) and N(alpha)-4-tosyl-l-arginine methyl ester hydrochloride on the recognition and catalysis in ATP hydrolysis. Dalton transactions (Cambridge, England : 2003) 20080227
Kinetic properties of three isoforms of trypsin isolated from the pyloric caeca of chum salmon (Oncorhynchus keta). Biological & pharmaceutical bulletin 20070901
Synthesis and evaluation of a small library of graftable thrombin inhibitors derived from (L)-arginine. European journal of medicinal chemistry 20070101
Association of estrogen receptor-alpha and progesterone receptor A expression with hormonal mammary carcinogenesis: role of the host microenvironment. Breast cancer research : BCR 20070101
Ozonation and combined ozone/H2O2, UV/ozone and UV/H2O2 for treatment of fuel oxygenates MTBE, ETBE, TAME, and DIPE from water--a comparison of removal efficiencies. Water science and technology : a journal of the International Association on Water Pollution Research 20070101
Identification of serine proteases from Leishmania braziliensis. Zeitschrift fur Naturforschung. C, Journal of biosciences 20070101
A novel plasminogen activator from Agkistrodon blomhoffii Ussurensis venom (ABUSV-PA): purification and characterization. Biochemical and biophysical research communications 20061006
Purification and characterization of trypsin from the spleen of tongol tuna (Thunnus tonggol). Journal of agricultural and food chemistry 20060726
Activation of MAPK ERK in peripheral nerve after injury. BMC neuroscience 20060101
Purification, primary structures and evolution of coagulant proteases from Deinagkistrodon actus venom. Toxicon : official journal of the International Society on Toxinology 20051215
Partial purification and characterization of digestive trypsin-like proteases from the velvet bean caterpillar, Anticarsia gemmatalis. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20050301
Isolation and characterization of trypsin from pyloric caeca of Monterey sardine Sardinops sagax caerulea. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20050101
Chronic ethanol exposure increases microtubule content in PC12 cells. BMC neuroscience 20050101
Small GTP-binding protein Rho-mediated signaling promotes proliferation of rheumatoid synovial fibroblasts. Arthritis research & therapy 20050101
Influence of oxygenated fuel additives and their metabolites on gamma-aminobutyric acidA (GABAA) receptor function in rat brain synaptoneurosomes. Toxicology letters 20040307
Analysis of the action of compounds that inhibit the germination of spores of Bacillus species. Journal of applied microbiology 20040101
Aprotinin suppresses ACE-inhibitor cough triggered by TAME-esterase. Medical hypotheses 20040101
Purification and characterization of a thrombin like enzyme, elegaxobin II, with lys-bradykinin releasing activity from the venom of Trimeresurus elegans (Sakishima-Habu). Toxicon : official journal of the International Society on Toxinology 20030401
Effects of aspirin on N-alpha-tosyl L-arginine methyl ester [TAME]-esterase induced contractions on rat aorta in vitro. Fundamental & clinical pharmacology 20030201
Effect of genistein, a tyrosine kinase inhibitor, on TAME-esterase induced contractions in rat aorta in vitro. Indian journal of experimental biology 20021001
A novel low molecular weight hemorrhagic toxin from Trimeresurus flavoviridis (Vorojima) venom. Journal of natural toxins 20020801
Purification and characterization of the fusion protein trypsin-streptavidin expressed in Escherichia coli. Journal of protein chemistry 20020801
Isolation and characteristics of trypsin from pyloric ceca of the starfish Asterina pectinifera. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 20020601
Effect of vitamin C on endothelial dysfunction during N-alpha-tosyl L-arginine methyl ester [TAME]-esterase induced contractions in rat aorta in vitro. Indian journal of experimental biology 20020501
Kinetic peculiarities of human tissue kallikrein: 1--substrate activation in the catalyzed hydrolysis of H-D-valyl-L-leucyl-L-arginine 4-nitroanilide and H-D-valyl-L-leucyl-L-lysine 4-nitroanilide; 2--substrate inhibition in the catalyzed hydrolysis of N alpha-p-tosyl-L-arginine methyl ester. Archives of biochemistry and biophysics 20020401
Variations in biochemical and pharmacological properties of Indian cobra (Naja naja naja) venom due to geographical distribution. Molecular and cellular biochemistry 20020101
Tissue localization of overproduced esterases in the mosquito Culex pipiens (Diptera: Culicidae). Journal of medical entomology 20011101
Experimental evidence for a non-renin mediated pathway during TAME-esterase induced contractions in rat aorta in vitro. Indian journal of experimental biology 20010901
The pH dependence of serpin-proteinase complex dissociation reveals a mechanism of complex stabilization involving inactive and active conformational states of the proteinase which are perturbable by calcium. The Journal of biological chemistry 20010831
Thrombin-like enzyme, flavovilase, with kinin-releasing activity from Trimeresurus flavoviridis (habu) venom. Journal of natural toxins 20010801
Aerobic biodegradation of an oxygenates mixture: ETBE, MTBE and TAME in an upflow fixed-bed reactor. Water research 20010501
Biotransformation of MTBE, ETBE, and TAME after inhalation or ingestion in rats and humans. Research report (Health Effects Institute) 20010501
Isolation and characterization of two aerobic bacterial strains that completely degrade ethyl tert-butyl ether (ETBE). Applied microbiology and biotechnology 20010401
The allosteric effect of salt on human mast cell tryptase. Biochimica et biophysica acta 19880921
Properties