Name: Name:Ly2334737
Brand: Angene
SKU: AG00GU44
Rating: 90 (10 reviews)

Ly2334737

CAS No.:

892128-60-8

Catalog Number:

AG00GU44

Molecular Formula:

C17H25F2N3O5

Molecular Weight:

389.3943

Pack Size

Purity

Availability

Location

Price(USD)

Quantity

5mg

99%

1 week

United States

$450

- +

10mg

99%

1 week

United States

$657

- +

50mg

99%

1 week

United States

$1482

- +

100mg

99%

1 week

United States

$2273

- +

Product Description

Catalog Number:

AG00GU44

Chemical Name:

Ly2334737

CAS Number:

892128-60-8

Molecular Formula:

C17H25F2N3O5

Molecular Weight:

389.3943

MDL Number:

MFCD25976631

IUPAC Name:

N-[1-[(2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-2-oxopyrimidin-4-yl]-2-propylpentanamide

InChI:

InChI=1S/C17H25F2N3O5/c1-3-5-10(6-4-2)14(25)20-12-7-8-22(16(26)21-12)15-17(18,19)13(24)11(9-23)27-15/h7-8,10-11,13,15,23-24H,3-6,9H2,1-2H3,(H,20,21,25,26)/t11-,13-,15-/m1/s1

InChI Key:

MEOYFIHNRBNEPI-UXIGCNINSA-N

SMILES:

CCCC(C(=O)Nc1ccn(c(=O)n1)[C@@H]1O[C@@H]([C@H](C1(F)F)O)CO)CCC

UNII:

YLR364XYSA

Properties

Complexity:

620

Compound Is Canonicalized:

Yes

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Defined Bond Stereocenter Count:

Exact Mass:

389.176g/mol

Formal Charge:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Isotope Atom Count:

Molecular Weight:

389.4g/mol

Monoisotopic Mass:

389.176g/mol

Rotatable Bond Count:

Topological Polar Surface Area:

112A^2

Undefined Atom Stereocenter Count:

Undefined Bond Stereocenter Count:

XLogP3:

1.7

Literature

Title	Journal
Phase I study of Oral gemcitabine prodrug (LY2334737) alone and in combination with erlotinib in patients with advanced solid tumors.	Clinical cancer research : an official journal of the American Association for Cancer Research 20110915
Synthesis, crystallization, and biological evaluation of an orally active prodrug of gemcitabine.	Journal of medicinal chemistry 20091126