Name: Name:c-FMS inhibitor
Brand: Angene
SKU: AG00GU2H
Rating: 90 (10 reviews)

c-FMS inhibitor

CAS No.:

885704-21-2

Catalog Number:

AG00GU2H

Molecular Formula:

C23H30N6O

Molecular Weight:

406.5239

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Product Description

Catalog Number:

AG00GU2H

Chemical Name:

c-FMS inhibitor

CAS Number:

885704-21-2

Molecular Formula:

C23H30N6O

Molecular Weight:

406.5239

MDL Number:

MFCD22124465

IUPAC Name:

4-cyano-N-[4-(4-methylpiperazin-1-yl)-2-(4-methylpiperidin-1-yl)phenyl]-1H-pyrrole-2-carboxamide

InChI:

InChI=1S/C23H30N6O/c1-17-5-7-29(8-6-17)22-14-19(28-11-9-27(2)10-12-28)3-4-20(22)26-23(30)21-13-18(15-24)16-25-21/h3-4,13-14,16-17,25H,5-12H2,1-2H3,(H,26,30)

InChI Key:

DXPSQKSTVIVZLV-UHFFFAOYSA-N

SMILES:

N#Cc1c[nH]c(c1)C(=O)Nc1ccc(cc1N1CCC(CC1)C)N1CCN(CC1)C

Properties

Complexity:

631

Compound Is Canonicalized:

Yes

Covalently-Bonded Unit Count:

Defined Atom Stereocenter Count:

Defined Bond Stereocenter Count:

Exact Mass:

406.248g/mol

Formal Charge:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Hydrogen Bond Donor Count:

Isotope Atom Count:

Molecular Weight:

406.534g/mol

Monoisotopic Mass:

406.248g/mol

Rotatable Bond Count:

Topological Polar Surface Area:

78.4A^2

Undefined Atom Stereocenter Count:

Undefined Bond Stereocenter Count:

XLogP3:

2.9

Literature

Title	Journal
Design, Synthesis and Biological Evaluation of a Series of Novel Axl Kinase Inhibitors.	ACS medicinal chemistry letters 20111208
Optimization of a potent class of arylamide colony-stimulating factor-1 receptor inhibitors leading to anti-inflammatory clinical candidate 4-cyano-N-[2-(1-cyclohexen-1-yl)-4-[1-[(dimethylamino)acetyl]-4-piperidinyl]phenyl]-1H-imidazole-2-carboxamide (JNJ-28312141).	Journal of medicinal chemistry 20111124

Properties