MF63
Title | Journal |
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Dynamic modeling of human 5-lipoxygenase-inhibitor interactions helps to discover novel inhibitors. | Journal of medicinal chemistry 20120322 |
Synthesis and SAR study of imidazoquinolines as a novel structural class of microsomal prostaglandin E₂ synthase-1 inhibitors. | Bioorganic & medicinal chemistry letters 20120101 |
Trisubstituted ureas as potent and selective mPGES-1 inhibitors. | Bioorganic & medicinal chemistry letters 20110301 |
Microsomal prostaglandin e synthase-1 in rheumatic diseases. | Frontiers in pharmacology 20100101 |
Discovery of disubstituted phenanthrene imidazoles as potent, selective and orally active mPGES-1 inhibitors. | Bioorganic & medicinal chemistry letters 20091015 |
MF498 [N-{[4-(5,9-Diethoxy-6-oxo-6,8-dihydro-7H-pyrrolo[3,4-g]quinolin-7-yl)-3-methylbenzyl]sulfonyl}-2-(2-methoxyphenyl)acetamide], a selective E prostanoid receptor 4 antagonist, relieves joint inflammation and pain in rodent models of rheumatoid and osteoarthritis. | The Journal of pharmacology and experimental therapeutics 20080501 |
Substituted phenanthrene imidazoles as potent, selective, and orally active mPGES-1 inhibitors. | Bioorganic & medicinal chemistry letters 20071215 |