Home Other Building Blocks bisBenziMide H 33342 trihydrochloride

bisBenziMide H 33342 trihydrochloride

CAS No.:
875756-97-1
Catalog Number:
AG00GTC3
Molecular Formula:
C27H31Cl3N6O
Molecular Weight:
561.9336
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
25mg
≥98%
1 week
United States
$96
- +
50mg
≥98%
1 week
United States
$123
- +
100mg
99%
1 week
United States
$175
- +
500mg
≥98%
1 week
United States
$348
- +
Product Description
Catalog Number:
AG00GTC3
Chemical Name:
bisBenziMide H 33342 trihydrochloride
CAS Number:
875756-97-1
Molecular Formula:
C27H31Cl3N6O
Molecular Weight:
561.9336
MDL Number:
MFCD00150074
IUPAC Name:
2-(4-ethoxyphenyl)-6-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-benzimidazole;trihydrochloride
InChI:
InChI=1S/C27H28N6O.3ClH/c1-3-34-21-8-4-18(5-9-21)26-28-22-10-6-19(16-24(22)30-26)27-29-23-11-7-20(17-25(23)31-27)33-14-12-32(2)13-15-33;;;/h4-11,16-17H,3,12-15H2,1-2H3,(H,28,30)(H,29,31);3*1H
InChI Key:
JABNPSKWVNCGMX-UHFFFAOYSA-N
SMILES:
CCOc1ccc(cc1)c1[nH]c2c(n1)cc(cc2)c1nc2c([nH]1)ccc(c2)N1CCN(CC1)C.Cl.Cl.Cl
UNII:
P976261J69
Properties
Complexity:
664  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
4  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
560.162g/mol
Formal Charge:
0
Heavy Atom Count:
37  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
5  
Isotope Atom Count:
0
Molecular Weight:
561.936g/mol
Monoisotopic Mass:
560.162g/mol
Rotatable Bond Count:
5  
Topological Polar Surface Area:
73.1A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
Literature
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Protective effects of epoxyeicosatrienoic acids on human endothelial cells from the pulmonary and coronary vasculature. American journal of physiology. Heart and circulatory physiology 20060801
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Spectral analysis of the DNA targeting bisalkylaminoanthraquinone DRAQ5 in intact living cells. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060801
Antiproliferative and antioxidant properties of an enzymatic hydrolysate from brown alga, Ecklonia cava. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20060701
Cell sorting but not serum starvation is effective for SV40 human corneal epithelial cell cycle synchronization. Experimental eye research 20060701
The presence of ABCG2-dependent side population cells in human periodontal ligaments. Biochemical and biophysical research communications 20060616
Cell death effects of resin-based dental material compounds and mercurials in human gingival fibroblasts. Archives of toxicology 20060601
Voltage-dependent potassium channels are involved in glutamate-induced apoptosis of rat hippocampal neurons. Neuroscience letters 20060501
Zn(II)-phthalocyanines as phototherapeutic agents for cutaneous diseases. Photosensitization of fibroblasts and keratinocytes. Journal of photochemistry and photobiology. B, Biology 20060403
Neuroprotection via inhibition of nitric oxide synthase by bis(7)-tacrine. Neuroreport 20060403
Usefulness of a triple fluorochrome combination Merocyanine 540/Yo-Pro 1/Hoechst 33342 in assessing membrane stability of viable frozen-thawed spermatozoa from Estonian Holstein AI bulls. Theriogenology 20060401
Functional gene cloning and characterization of MdeA, a multidrug efflux pump from Staphylococcus aureus. Biological & pharmaceutical bulletin 20060401
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Analysis of living S. cerevisiae cell states--a three color approach. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060301
Effect of gonadotrophin stimulation on mouse oocyte quality and subsequent embryonic development in vitro. Reproductive biomedicine online 20060301
Inhibition of apoptosis by p26: implications for small heat shock protein function during Artemia development. Cell stress & chaperones 20060301
Microscopy under pressure--an optical chamber system for fluorescence microscopic analysis of living cells under high hydrostatic pressure. Microscopy research and technique 20060201
Arsenic trioxide induces apoptosis of human monocytes during macrophagic differentiation through nuclear factor-kappaB-related survival pathway down-regulation. The Journal of pharmacology and experimental therapeutics 20060101
Leishmania donovani: differential activities of classical topoisomerase inhibitors and antileishmanials against parasite and host cells at the level of DNA topoisomerase I and in cytotoxicity assays. Experimental parasitology 20060101
A novel subpopulation lacking Oct4 expression in the testicular side population. International journal of molecular medicine 20060101
Melanoma, a tumor based on a mutant stem cell? The Journal of investigative dermatology 20060101
Neuroprotective effects of green and black teas and their catechin gallate esters against beta-amyloid-induced toxicity. The European journal of neuroscience 20060101
Demonstration of hematopoietic stem cells in ginbuna carp (Carassius auratus langsdorfii) kidney. Developmental and comparative immunology 20060101
Cytotoxicity of different selective serotonin reuptake inhibitors (SSRIs) against cancer cells. Journal of experimental therapeutics & oncology 20060101
Proton motive force-dependent Hoechst 33342 transport by the ABC transporter LmrA of Lactococcus lactis. Biochemistry 20051227
Accumulation of DNA, nuclear and mitochondrial debris, and ROS at sites of age-related cortical cataract in mice. Investigative ophthalmology & visual science 20051201
Effect of NMDA on staurosporine-induced activation of caspase-3 and LDH release in mouse neocortical and hippocampal cells. Brain research. Developmental brain research 20051107
The Q-loop disengages from the first intracellular loop during the catalytic cycle of the multidrug ABC transporter BmrA. The Journal of biological chemistry 20051104
Reactive oxygen species-mediated beta-cleavage of the prion protein in the cellular response to oxidative stress. The Journal of biological chemistry 20051028
Influence of initial charge state on fragmentation patterns for noncovalent drug/DNA duplex complexes. Journal of mass spectrometry : JMS 20051001
Neuroprotective effects of minocycline against in vitro and in vivo retinal ganglion cell damage. Brain research 20050816
Fully grown mouse oocyte contains transcription inhibiting activity which acts through histone deacetylation. Molecular reproduction and development 20050801
IB1/JIP-1 controls JNK activation and increased during prostatic LNCaP cells neuroendocrine differentiation. Cellular signalling 20050801
Comparison of different methods of CAIX quantification in relation to hypoxia in three human head and neck tumor lines. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 20050801
Quantitative cell-based high-content screening for vasopressin receptor agonists using transfluor technology. Journal of biomolecular screening 20050801
Resistance mechanism development to the topoisomerase-I inhibitor Hoechst 33342 by Leishmania donovani. Parasitology 20050801
Hypoxic cell turnover in different solid tumor lines. International journal of radiation oncology, biology, physics 20050715
Thymidine analogues to assess microperfusion in human tumors. International journal of radiation oncology, biology, physics 20050715
Effect of staining and sorting on boar sperm membrane integrity, mitochondrial activity and in vitro blastocyst development. Theriogenology 20050701
Increased functional expression of P-glycoprotein in Caco-2 TC7 cells exposed long-term to cadmium. Toxicology in vitro : an international journal published in association with BIBRA 20050601
Cytotoxic effects of 110 reference compounds on HepG2 cells and for 60 compounds on HeLa, ECC-1 and CHO cells. II mechanistic assays on NAD(P)H, ATP and DNA contents. Toxicology in vitro : an international journal published in association with BIBRA 20050601
Dependence of FDG uptake on tumor microenvironment. International journal of radiation oncology, biology, physics 20050601
Flavonoid structure-activity studies identify 6-prenylchrysin and tectochrysin as potent and specific inhibitors of breast cancer resistance protein ABCG2. Cancer research 20050601
Immunosuppressive immunophilin ligands attenuate damage in cultured rat astrocytes depleted of glutathione and exposed to simulated ischemia in vitro. Comparison with N-acetylcysteine. Neurotoxicology 20050601
Minocycline inhibits oxidative stress and decreases in vitro and in vivo ischemic neuronal damage. Brain research 20050517
The effect of quercetin on pro-apoptotic activity of cisplatin in HeLa cells. Biochemical pharmacology 20050501
Differences in the incidence of apoptosis between in vivo and in vitro produced blastocysts of farm animal species: a comparative study. Theriogenology 20050501
[Evaluation of the survival of bone marrow mononucleate cells transplanted in a rat model of striatal lesion with quinolinic acid]. Revista de neurologia 20050501
Protective effects of Delta(9)-tetrahydrocannabinol against N-methyl-d-aspartate-induced AF5 cell death. Brain research. Molecular brain research 20050404
The DNA minor groove binding agents Hoechst 33258 and 33342 enhance recombinant adeno-associated virus (rAAV) transgene expression. The journal of gene medicine 20050401
7-Ketocholesterol favors lipid accumulation and colocalizes with Nile Red positive cytoplasmic structures formed during 7-ketocholesterol-induced apoptosis: analysis by flow cytometry, FRET biphoton spectral imaging microscopy, and subcellular fractionation. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20050401
Protection by exogenous pyruvate through a mechanism related to monocarboxylate transporters against cell death induced by hydrogen peroxide in cultured rat cortical neurons. Journal of neurochemistry 20050401
Assessment of regional tumor hypoxia using 18F-fluoromisonidazole and 64Cu(II)-diacetyl-bis(N4-methylthiosemicarbazone) positron emission tomography: Comparative study featuring microPET imaging, Po2 probe measurement, autoradiography, and fluorescent microscopy in the R3327-AT and FaDu rat tumor models. International journal of radiation oncology, biology, physics 20050401
NF-kappaB pathway protects cochlear hair cells from aminoglycoside-induced ototoxicity. Journal of neuroscience research 20050301
Function-dependent conformational changes of the ABCG2 multidrug transporter modify its interaction with a monoclonal antibody on the cell surface. The Journal of biological chemistry 20050211
Development of an ischemic tolerance model in a PC12 cell line. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20050201
Single amino acid (482) variants of the ABCG2 multidrug transporter: major differences in transport capacity and substrate recognition. Biochimica et biophysica acta 20050201
[Comparison between two methods for staining DNA of apoptotic spermatozoa]. Zhonghua nan ke xue = National journal of andrology 20050201
Pro-apoptotic effects of the flavonoid luteolin in rat H4IIE cells. Toxicology 20050131
Electrostatic trapping of double-stranded DNA by using cadmium hydroxide nanostrands. Nano letters 20050101
Flow cytometric monitoring of fluorescent drug retention and efflux. Methods in molecular medicine 20050101
Characterization and localization of side population cells in mouse skin. Stem cells (Dayton, Ohio) 20050101
Single UV excitation of Hoechst 33342 and propidium iodide for viability assessment of rhesus monkey spermatozoa using flow cytometry. Archives of andrology 20050101
Potential protective effects of NSAIDs/ASA in oxidatively stressed human lens epithelial cells and intact mouse lenses in culture. Ophthalmic research 20050101
Bone marrow stromal cells increase astrocyte survival via upregulation of phosphoinositide 3-kinase/threonine protein kinase and mitogen-activated protein kinase kinase/extracellular signal-regulated kinase pathways and stimulate astrocyte trophic factor gene expression after anaerobic insult. Neuroscience 20050101
An improved definition of mouse mammary epithelial side population cells. Cytotherapy 20050101
Heterogeneity in the radiosensitizing effects of the DNA ligand hoechst-33342 in human tumor cell lines. Journal of cancer research and therapeutics 20050101
Mitochondrial targeting sequence of the influenza A virus PB1-F2 protein and its function in mitochondria. FEBS letters 20041217
DNA ligand Hoechst-33342 enhances UV induced cytotoxicity in human glioma cell lines. Journal of photochemistry and photobiology. B, Biology 20041202
Histone H2AX phosphorylation induced by selective photolysis of BrdU-labeled DNA with UV light: relation to cell cycle phase. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20041101
Differential staining of DNA and RNA. Current protocols in cytometry 20041101
Energetics of wild-type and mutant multidrug resistance secondary transporter LmrP of Lactococcus lactis. Biochimica et biophysica acta 20041004
Biological responses in known bystander cells relative to known microbeam-irradiated cells. Radiation research 20041001
Celastraceae sesquiterpenes as a new class of modulators that bind specifically to human P-glycoprotein and reverse cellular multidrug resistance. Cancer research 20041001
Proton motive force mediates a reorientation of the cytosolic domains of the multidrug transporter LmrP. Cellular and molecular life sciences : CMLS 20041001
Inhibition of Leishmania donovani promastigote DNA topoisomerase I and human monocyte DNA topoisomerases I and II by antimonial drugs and classical antitopoisomerase agents. The Journal of parasitology 20041001
A new human breast carcinoma cell line resistant to DNA-damaging drugs. Alternatives to laboratory animals : ATLA 20041001
Inhibition of amyloid-beta-induced neurotoxicity and apoptosis by moderate ethanol preconditioning. Neuroreport 20040915
Ciglitizone and 15d PGJ2 induce apoptosis in Jurkat and Raji cells. International immunopharmacology 20040901
2-deoxy-D-glucose enhances the cytotoxicity of topoisomerase inhibitors in human tumor cell lines. Cancer biology & therapy 20040901
The remyelinating potential and in vitro differentiation of MOG-expressing oligodendrocyte precursors isolated from the adult rat CNS. The European journal of neuroscience 20040901
Effect of beta-mercaptoethanol or epidermal growth factor supplementation on in vitro maturation of canine oocytes collected from dogs with different stages of the estrus cycle. Journal of veterinary science 20040901
Hypoxia and Photofrin uptake in the intraperitoneal carcinomatosis and sarcomatosis of photodynamic therapy patients. Clinical cancer research : an official journal of the American Association for Cancer Research 20040715
Retinal microvascular patency in the diabetic rat. International ophthalmology 20040701
Erk1/2 and Akt kinases are involved in the protective effect of aniracetam in astrocytes subjected to simulated ischemia in vitro. European journal of pharmacology 20040628
Cannabinoid CB1 receptor protein expression in the rat choroid plexus: a possible involvement of cannabinoids in the regulation of cerebrospinal fluid. Neuroscience letters 20040624
ABC transporter activities of murine hematopoietic stem cells vary according to their developmental and activation status. Blood 20040615
Characterization of YvcC (BmrA), a multidrug ABC transporter constitutively expressed in Bacillus subtilis. Biochemistry 20040615
The apoptotic and necrotic effects of tomatine adjuvant. Vaccine 20040602
Auranofin induces apoptosis and when combined with retinoic acid enhances differentiation of acute promyelocytic leukaemia cells in vitro. British journal of pharmacology 20040601
DFNA5: hearing impairment exon instead of hearing impairment gene? Journal of medical genetics 20040601
In vitro assessment of the efficacy of thermal therapy in human benign prostatic hyperplasia. International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 20040601
Human limbal epithelium contains side population cells expressing the ATP-binding cassette transporter ABCG2. FEBS letters 20040507
Genotoxic and antiapoptotic effect of nicotine on human gingival fibroblasts. Toxicological sciences : an official journal of the Society of Toxicology 20040501
Hematopoietic and nonhematopoietic potentials of Hoechst(low)/side population cells isolated from adult rat kidney. Kidney international 20040501
Evidence of tubular hypoxia in the early phase in the remnant kidney model. Journal of the American Society of Nephrology : JASN 20040501
Stage-specific effect of N-(4-hydroxyphenyl)retinamide on cell growth in squamous cell carcinogenesis. Molecular carcinogenesis 20040501
Differential regulation of the mitochondrial and death receptor pathways in neural stem cells. The European journal of neuroscience 20040501
Among circulating hematopoietic cells, B-CLL uniquely expresses functional EPAC1, but EPAC1-mediated Rap1 activation does not account for PDE4 inhibitor-induced apoptosis. Blood 20040401
Mechanisms of coxsackievirus B5 mediated beta-cell death depend on the multiplicity of infection. Journal of medical virology 20040401
Amplification of nuclear aldolase A in mouse cell mutants resistant to Hoechst 33342. Biochemical and biophysical research communications 20040319
Irradiation attenuates neurogenesis and exacerbates ischemia-induced deficits. Annals of neurology 20040301
Hoechst 33342 is a useful cell tracer for a long-term investigation of articular cartilage repair. Archives of histology and cytology 20040301
Inhibitory effect of IGF-I on induced apoptosis in mouse preimplantation embryos cultured in vitro. Theriogenology 20040201
Analysis of the fluorescence of monodansylcadaverine-positive cytoplasmic structures during 7-ketocholesterol-induced cell death. Analytical and quantitative cytology and histology 20040201
Modulation of ATP levels alters the mode of hydrogen peroxide-induced cell death in primary cortical cultures: effects of putative neuroprotective agents. Brain research 20040130
Overexpression of superoxide dismutase 1 protects against beta-amyloid peptide toxicity: effect of estrogen and copper chelators. Neurochemistry international 20040101
Bioassay using epidermal keratinocytes to determine phosphorylation status of the epidermal growth factor receptor in distant neoplasms. International journal of oncology 20040101
The chemokine receptor CXCR4 and not the N-methyl-D-aspartate receptor mediates gp120 neurotoxicity in cerebellar granule cells. Journal of neuroscience research 20040101
Enrichment and characterization of mouse putative epidermal stem cells. Cell biology international 20040101
Selected cyclic dipeptides inhibit cancer cell growth and induce apoptosis in HT-29 colon cancer cells. Anticancer research 20040101
Mitochondrial membrane potential change induced by Hoechst 33342 in myelogenous leukemia cell line HL-60. Annals of clinical and laboratory science 20040101
Methanethiosulfonate derivatives of rhodamine and verapamil activate human P-glycoprotein at different sites. The Journal of biological chemistry 20031212
Minor groove binding DNA ligands with expanded A/T sequence length recognition, selective binding to bent DNA regions and enhanced fluorescent properties. Biochemistry 20031118
Glial cells maintain synaptic structure and function and promote development of the neuromuscular junction in vivo. Neuron 20031030
Akt signaling regulates side population cell phenotype via Bcrp1 translocation. The Journal of biological chemistry 20031003
Phenotype and hematopoietic potential of side population cells throughout embryonic development. Blood 20031001
Inhibition of signal transduction in EGF-dependent epithelial cell lines. International journal of molecular medicine 20031001
Fission yeast Sap1 protein is essential for chromosome stability. Eukaryotic cell 20031001
Elimination of serotonergic cells induces a marked increase in generation of dopaminergic neurons from mesencephalic precursors. The European journal of neuroscience 20031001
Induced cell death of preimplantation mouse embryos cultured in vitro evaluated by comet assay. Theriogenology 20030901
Hoechst 33342 alters luciferase gene expression in transfected BC3H-1 myocytes. Archives of pathology & laboratory medicine 20030901
Caspase-3 dependent proteolytic activation of protein kinase C delta mediates and regulates 1-methyl-4-phenylpyridinium (MPP+)-induced apoptotic cell death in dopaminergic cells: relevance to oxidative stress in dopaminergic degeneration. The European journal of neuroscience 20030901
Influence of phenyl ring disubstitution on bisbenzimidazole and terbenzimidazole cytotoxicity: synthesis and biological evaluation as radioprotectors. Journal of medicinal chemistry 20030828
Effects of overexpression of dimethylarginine dimethylaminohydrolase on tumor angiogenesis assessed by susceptibility magnetic resonance imaging. Cancer research 20030815
Carboxylesterase-mediated sensitization of human tumor cells to CPT-11 cannot override ABCG2-mediated drug resistance. Molecular pharmacology 20030801
Novel method for the isolation and characterisation of the putative prostatic stem cell. Cytometry. Part A : the journal of the International Society for Analytical Cytology 20030801
The varicella-zoster virus induces apoptosis in vitro in subpopulations of primary human peripheral blood mononuclear cells. Microbes and infection 20030801
Reversal of Bcl-2-mediated resistance of the EW36 human B-cell lymphoma cell line to arsenite- and pesticide-induced apoptosis by PK11195, a ligand of the mitochondrial benzodiazepine receptor. Toxicological sciences : an official journal of the Society of Toxicology 20030701
Hepatic oval cells have the side population phenotype defined by expression of ATP-binding cassette transporter ABCG2/BCRP1. The American journal of pathology 20030701
Cigarette smoke extract induces oxidative stress and apoptosis in human lung fibroblasts. American journal of physiology. Lung cellular and molecular physiology 20030601
Sanguinarine-induced apoptosis is associated with an early and severe cellular glutathione depletion. Cancer chemotherapy and pharmacology 20030601
Direct identification and enrichment of retinal stem cells/progenitors by Hoechst dye efflux assay. Investigative ophthalmology & visual science 20030601
Hsp70 prevents nitric oxide-induced apoptosis in articular chondrocytes. Arthritis and rheumatism 20030601
Effect of nitric oxide on the proliferation of cultured porcine trabecular meshwork cells. Korean journal of ophthalmology : KJO 20030601
Dual fluorescence analysis of DNA apoptosis in sperm. American journal of obstetrics and gynecology 20030501
Effects of the proapoptotic drug prodigiosin on cell cycle-related proteins in Jurkat T cells. Histology and histopathology 20030401
Use of the confocal laser scanning microscope in studies on the developmental biology of marine crustaceans. Microscopy research and technique 20030301
Quantitative fluorescence imaging approach for the study of polyploidization in hepatocytes. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 20030301
Migration of cochlear lateral wall cells. Hearing research 20030301
Colchicine induces apoptosis in organotypic hippocampal slice cultures. Brain research 20030227
Transition state P-glycoprotein binds drugs and modulators with unchanged affinity, suggesting a concerted transport mechanism. Biochemistry 20030211
Functional and molecular characterisation of mammary side population cells. Breast cancer research : BCR 20030101
Flow cytometric analysis of cell cycle control by tumor suppressor genes. Methods in molecular biology (Clifton, N.J.) 20030101
Mode of cell death induced in Chinese hamster cells by sequence-selective DNA minor groove binding nitrogen mustards: comparison with untargeted mustards and with Hoechst 33342. Oncology research 20030101
Microglial cell death induced by a low concentration of polyamines. Neuroscience 20030101
HaCaT cell proliferation influenced by melatonin. Skin pharmacology and applied skin physiology 20030101
In vitro and in vivo assessment of functional capacity of flow cytometrically sorted ram spermatozoa after freezing and thawing. Reproduction, fertility, and development 20030101
Characterization of drug transport, ATP hydrolysis, and nucleotide trapping by the human ABCG2 multidrug transporter. Modulation of substrate specificity by a point mutation. The Journal of biological chemistry 20021213
Apoptosis: biochemical aspects and clinical implications. Clinica chimica acta; international journal of clinical chemistry 20021201
The development of combretastatin A4 phosphate as a vascular targeting agent. International journal of radiation oncology, biology, physics 20021201
Enhancement of vascular targeting by inhibitors of nitric oxide synthase. International journal of radiation oncology, biology, physics 20021201
3,4-Methylenedioxymethamphetamine ('Ecstasy') induces apoptosis of cultured rat liver cells. Biochimica et biophysica acta 20021009
Low density lipoprotein can cause death of islet beta-cells by its cellular uptake and oxidative modification. Endocrinology 20020901
Purinergic and muscarinic modulation of the cell cycle and calcium signaling in the chick retinal ventricular zone. The Journal of neuroscience : the official journal of the Society for Neuroscience 20020901
Roles of endogenous glutathione levels on 6-hydroxydopamine-induced apoptotic neuronal cell death in human neuroblastoma SK-N-SH cells. Neuropharmacology 20020901
Heat shock inhibits hydrogen peroxide-induced apoptosis in cultured astrocytes. Brain research 20020816
Liver and marrow of adult mdr-1a/1b(-/-) mice show normal generation, function, and multi-tissue trafficking of primitive hematopoietic cells. Experimental hematology 20020801
Helicobacter pylori prevents proliferative stage of angiogenesis in vitro: role of cytokines. Digestive diseases and sciences 20020801
Effect of Hoechst 33342 staining on developmental competence of prepubertal goat oocytes. Zygote (Cambridge, England) 20020801
Acidic residues in the lactococcal multidrug efflux pump LmrP play critical roles in transport of lipophilic cationic compounds. The Journal of biological chemistry 20020719
PTK787/ZK 222584, a specific vascular endothelial growth factor-receptor tyrosine kinase inhibitor, affects the anatomy of the tumor vascular bed and the functional vascular properties as detected by dynamic enhanced magnetic resonance imaging. Cancer research 20020715
Nuclear shrinkage and other markers of neuronal cell death after oxygen-glucose deprivation in rat hippocampal slice cultures. Neuroscience letters 20020712
Ceramide accumulation is independent of camptothecin-induced apoptosis in prostate cancer LNCaP cells. Biochemical and biophysical research communications 20020607
Activity of the GR in G2 and mitosis. Molecular endocrinology (Baltimore, Md.) 20020601
Oxidative stress mediates cell surface expression of SS-A/Ro antigen on keratinocytes. Free radical biology & medicine 20020515
A novel flow cytometric technique for drug cytotoxicity gives results comparable to colony-forming assays. Cytometry 20020501
Parthenogenesis of rabbit oocytes activated by different stimuli. Animal reproduction science 20020415
Effects of immunophilin ligands on hydrogen peroxide-induced apoptosis in C6 glioma cells. Synapse (New York, N.Y.) 20020301
Structural and functional asymmetry of the nucleotide-binding domains of P-glycoprotein investigated by attenuated total reflection Fourier transform infrared spectroscopy. The Journal of biological chemistry 20020215
Local hypoxia is produced at sites of intratumour injection. British journal of cancer 20020201
Microplate screening of the differential effects of test agents on Hoechst 33342, rhodamine 123, and rhodamine 6G accumulation in breast cancer cells that overexpress P-glycoprotein. Journal of biomolecular screening 20020201
The analysis of chromatin organisation allows selection of mouse antral oocytes competent for development to blastocyst. Zygote (Cambridge, England) 20020201
Lack of correlation between AT frequency and genome size in higher plants and the effect of nonrandomness of base sequences on dye binding. Cytometry 20020101
The multidrug resistance transporter ABCG2 (breast cancer resistance protein 1) effluxes Hoechst 33342 and is overexpressed in hematopoietic stem cells. Clinical cancer research : an official journal of the American Association for Cancer Research 20020101
Activity of the vascular targeting agent combretastatin A-4 disodium phosphate in a xenograft model of AIDS-associated Kaposi's sarcoma. Acta oncologica (Stockholm, Sweden) 20020101
[A cross drug resistance of mammalian cells with a high efficiency of 'DNA clearing']. Tsitologiia 20020101
Mitogen-activated protein kinase inhibitor, PD98059, inhibits rat retinal pigment epithelial cell replication by cell cycle arrest. Japanese journal of ophthalmology 20020101
Tris-benzimidazole derivatives: design, synthesis and DNA sequence recognition. Bioorganic & medicinal chemistry 20011101
Assessment of apoptosis and necrosis by DNA fragmentation and morphological criteria. Current protocols in cell biology 20011101
Evidence for simultaneous binding of dissimilar substrates by the Escherichia coli multidrug transporter MdfA. Biochemistry 20011023
Distribution of P2X receptors on astrocytes in juvenile rat hippocampus. Glia 20011001
Effects of acute and chronic doses of methoxy acetic acid on hamster sperm fertilising ability. Asian journal of andrology 20010901
A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia. Blood 20010815
A novel photosensitizer, 2-butylamino-2-demethoxy-hypocrellin B (2-BA-2-DMHB) - its photodynamic effects on HeLa cells: efficacy and apoptosis. Biochimica et biophysica acta 20010725
Perforin and granzyme B induce apoptosis in FasL-resistant colon carcinoma cells. Cancer immunology, immunotherapy : CII 20010601
Double-stranded DNA binding characteristics and subcellular distribution of a minor groove binding diphenyl ether bisbenzimidazole. Biochemistry 20010529
Transfection of annexin 1 in monocytic cells produces a high degree of spontaneous and stimulated apoptosis associated with caspase-3 activation. British journal of pharmacology 20010501
Nuclear shrinkage in live mouse hippocampal slices. Acta neuropathologica 20010501
Determining cell cycle stages by flow cytometry. Current protocols in cell biology 20010501
Transcriptional regulation of topoisomerase II alpha at confluence and pharmacological modulation of expression by bis-benzimidazole drugs. Molecular pharmacology 20010401
Alteration of argyrophilic nucleolar organizer region associated (Ag-NOR) proteins in apoptosis-induced human salivary gland cells and human oral squamous carcinoma cells. Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20010401
Direct and sensitized photoprocesses of bis-benzimidazole dyes and the effects of surfactants and DNA. Photochemistry and photobiology 20010401
Hoechst 33342-induced apoptosis is associated with decreased immunoreactive topoisomerase I and topoisomerase I-DNA complex formation. Annals of clinical and laboratory science 20010401
Fixation and permanent mounting of fluorescent probes after vital labelling of cultured cells. Acta histochemica 20010401
Inhibition of P-glycoprotein transport function by grapefruit juice psoralen. Pharmaceutical research 20010401
Prodigiosin-induced apoptosis in human colon cancer cells. Life sciences 20010316
Fluorescent dyes for cell viability: an application on prefixed conditions. Histochemistry and cell biology 20010301
Isolating a pure population of epidermal stem cells for use in tissue engineering. Experimental dermatology 20010201
Cryopreservation of equine embryos by open pulled straw, cryoloop, or conventional slow cooling methods. Theriogenology 20010115
Successful in vitro production of embryos in the red deer (Cervus elaphus) and the sika deer (Cervus nippon). Theriogenology 20010115
Flow cytometry of erythropoiesis in culture: bivariate profiles of fetal and adult hemoglobin. Methods in cell biology 20010101
Cytometry of antitumor drug-intracellular target interactions. Methods in cell biology 20010101
Resistance of tumor cells to chemo- and radiotherapy modulated by the three-dimensional architecture of solid tumors and spheroids. Methods in cell biology 20010101
Hoechst 33342-induced apoptosis is associated with intracellular accumulation of E2F-1 protein in BC3H-1 myocytes and HL-60 cells. Archives of pathology & laboratory medicine 20010101
Hypothermia prevents hearing loss and progressive hair cell loss after transient cochlear ischemia in gerbils. Neuroscience 20010101
Effects of genotypically different strains of Helicobacter pylori on human microvascular endothelial cells in vitro. Digestive diseases and sciences 20010101
Caspase-3 activity and carbonyl cyanide m-chlorophenylhydrazone-induced apoptosis in HL-60. Alternatives to laboratory animals : ATLA 20010101
Impact of proliferative activity and tumorigenic conversion on mitochondrial function of fibroblasts in 2D and 3D culture. Cell biology international 20010101
Lens epithelial cell protection by aminothiol WR-1065 and anetholedithiolethione from ionizing radiation. International journal of cancer 20010101
Induction of apoptosis by remoxipride metabolites in HL60 and CD34+/CD19- human bone marrow progenitor cells: potential relevance to remoxipride-induced aplastic anemia. Chemico-biological interactions 19990801
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