sales@angenesci.com
Login | Register
logo
Structures Search
Home Other Building Blocks ASP 2151

ASP 2151

CAS No.:
841301-32-4
Catalog Number:
AG00G7DL
Molecular Formula:
C24H26N4O5S
Molecular Weight:
482.5520
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
99%
1 week
United States
$265
- +
10mg
99%
1 week
United States
$404
- +
50mg
99%
1 week
United States
$960
- +
100mg
99%
1 week
United States
$1376
- +
Product Description
Catalog Number:
AG00G7DL
Chemical Name:
ASP 2151
CAS Number:
841301-32-4
Molecular Formula:
C24H26N4O5S
Molecular Weight:
482.5520
MDL Number:
MFCD19443709
IUPAC Name:
N-(2,6-dimethylphenyl)-N-[2-[4-(1,2,4-oxadiazol-3-yl)anilino]-2-oxoethyl]-1,1-dioxothiane-4-carboxamide
InChI:
InChI=1S/C24H26N4O5S/c1-16-4-3-5-17(2)22(16)28(24(30)19-10-12-34(31,32)13-11-19)14-21(29)26-20-8-6-18(7-9-20)23-25-15-33-27-23/h3-9,15,19H,10-14H2,1-2H3,(H,26,29)
InChI Key:
MNHNIVNAFBSLLX-UHFFFAOYSA-N
SMILES:
O=C(CN(c1c(C)cccc1C)C(=O)C1CCS(=O)(=O)CC1)Nc1ccc(cc1)c1nocn1
UNII:
94X46KW4AE
Properties
Complexity:
800  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
482.162g/mol
Formal Charge:
0
Heavy Atom Count:
34  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0
Molecular Weight:
482.555g/mol
Monoisotopic Mass:
482.162g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
131A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.6  
Literature
Title Journal
Efficacy of herpes virus helicase-primase inhibitor, ASP2151, for treating herpes simplex keratitis in mouse model. The British journal of ophthalmology 20130401
Synergistic activity of amenamevir (ASP2151) with nucleoside analogs against herpes simplex virus types 1 and 2 and varicella-zoster virus. Antiviral research 20130201
ASP2151 for the treatment of genital herpes: a randomized, double-blind, placebo- and valacyclovir-controlled, dose-finding study. The Journal of infectious diseases 20120401
Efficacy of ASP2151, a helicase-primase inhibitor, against thymidine kinase-deficient herpes simplex virus type 2 infection in vitro and in vivo. Antiviral research 20120201
Effect of ASP2151, a herpesvirus helicase-primase inhibitor, in a guinea pig model of genital herpes. Molecules (Basel, Switzerland) 20110825
ASP2151, a novel helicase-primase inhibitor, possesses antiviral activity against varicella-zoster virus and herpes simplex virus types 1 and 2. The Journal of antimicrobial chemotherapy 20100801
Properties