LewisYtetrasaccharide
Title | Journal |
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Differential glycosylation of MUC1 and CEACAM5 between normal mucosa and tumour tissue of colon cancer patients. | International journal of cancer 20120701 |
Expression of the tumor markers sialyl Lewis A, sialyl Lewis X, Lewis Y, Thomsen-Friedenreich antigen, galectin-1 and galectin-3 in human osteoblasts in vitro. | Anticancer research 20120501 |
Expression of the carbohydrate tumour marker Sialyl Lewis A, Sialyl Lewis X, Lewis Y and Thomsen-Friedenreich antigen in normal squamous epithelium of the uterine cervix, cervical dysplasia and cervical cancer. | Histology and histopathology 20120401 |
Structure of the lectin regulatory domain of the cholesterol-dependent cytolysin lectinolysin reveals the basis for its lewis antigen specificity. | Structure (London, England : 1993) 20120208 |
Lewis y regulate cell cycle related factors in ovarian carcinoma cell RMG-I in vitro via ERK and Akt signaling pathways. | International journal of molecular sciences 20120101 |
Interaction of Helicobacter pylori with C-type lectin dendritic cell-specific ICAM grabbing nonintegrin. | Journal of biomedicine & biotechnology 20120101 |
Studies on the synthesis of Lewis-y oligosaccharides. | Carbohydrate research 20111018 |
Lectin activity of the nucleocytoplasmic EUL protein from Arabidopsis thaliana. | Biochemical and biophysical research communications 20111014 |
Difucosylated oligosaccharide Lewis Y is contained within integrin αvβ3 on RL95-2 cells and required for endometrial receptivity. | Fertility and sterility 20110315 |
Enhancive effects of Lewis y antigen on CD44-mediated adhesion and spreading of human ovarian cancer cell line RMG-I. | Journal of experimental & clinical cancer research : CR 20110101 |
Study on the expression and clinical significances of lewis y antigen and integrin αv, β3 in epithelial ovarian tumors. | International journal of molecular sciences 20110101 |
The stimulation of IGF-1R expression by Lewis(y) antigen provides a powerful development mechanism of epithelial ovarian carcinoma. | International journal of molecular sciences 20110101 |
Increase in docetaxel-resistance of ovarian carcinoma-derived RMG-1 cells with enhanced expression of Lewis Y antigen. | International journal of molecular sciences 20110101 |
Expression and correlation of Lewis y antigen and integrins α5 and β1 in ovarian serous and mucinous carcinoma. | International journal of gynecological cancer : official journal of the International Gynecological Cancer Society 20101201 |
Removal of the outer Kdo from Helicobacter pylori lipopolysaccharide and its impact on the bacterial surface. | Molecular microbiology 20101101 |
Effects of Lewis Y antigen on the gene expression of multiple drug resistance-associated proteins in human ovarian cancer RMG-I-H cells. | Medical oncology (Northwood, London, England) 20100901 |
Enhancement of the adhesive and spreading potentials of ovarian carcinoma RMG-1 cells due to increased expression of integrin alpha5beta1 with the Lewis Y-structure on transfection of the alpha1,2-fucosyltransferase gene. | Biochimie 20100701 |
Gene-modified T cells as immunotherapy for multiple myeloma and acute myeloid leukemia expressing the Lewis Y antigen. | Gene therapy 20100501 |
Lewis(y) antigen stimulates the growth of ovarian cancer cells via regulation of the epidermal growth factor receptor pathway. | Oncology reports 20100301 |
Lewis (y) antigen overexpression increases the expression of MMP-2 and MMP-9 and invasion of human ovarian cancer cells. | International journal of molecular sciences 20100101 |
Lewis Y promotes growth and adhesion of ovarian carcinoma-derived RMG-I cells by upregulating growth factors. | International journal of molecular sciences 20100101 |
Host-dependent Lewis (Le) antigen expression in Helicobacter pylori cells recovered from Leb-transgenic mice. | The Journal of experimental medicine 20091221 |
Phase I biodistribution and pharmacokinetic study of Lewis Y-targeting immunoconjugate CMD-193 in patients with advanced epithelial cancers. | Clinical cancer research : an official journal of the American Association for Cancer Research 20091101 |
Differential recognition and hydrolysis of host carbohydrate antigens by Streptococcus pneumoniae family 98 glycoside hydrolases. | The Journal of biological chemistry 20090918 |
Complex N-glycans or core 1-derived O-glycans are not required for the expression of stage-specific antigens SSEA-1, SSEA-3, SSEA-4, or Le(Y) in the preimplantation mouse embryo. | Glycoconjugate journal 20090401 |
Glycomics and proteomics analyses of mouse uterine luminal fluid revealed a predominance of Lewis Y and X epitopes on specific protein carriers. | Molecular & cellular proteomics : MCP 20090201 |
Breast cancer humoral immune response: involvement of Lewis y through the detection of circulating immune complexes and association with Mucin 1 (MUC1). | Journal of experimental & clinical cancer research : CR 20090101 |
Is there a link between the lipopolysaccharide of Helicobacter pylori gastric MALT lymphoma associated strains and lymphoma pathogenesis? | PloS one 20090101 |
A possible role for metallic ions in the carbohydrate cluster recognition displayed by a Lewis Y specific antibody. | PloS one 20090101 |
Helicobacter pylori lipopolysaccharide modification, Lewis antigen expression, and gastric colonization are cholesterol-dependent. | BMC microbiology 20090101 |
Lewis y antigen promotes the proliferation of ovarian carcinoma-derived RMG-I cells through the PI3K/Akt signaling pathway. | Journal of experimental & clinical cancer research : CR 20090101 |
Relevance of fucosylation and Lewis antigen expression in the bacterial gastroduodenal pathogen Helicobacter pylori. | Carbohydrate research 20080811 |
Disulfide bond bridged divalent antibody-toxin, (Fab-PE38fl)2, with the toxin PE38 fused to the light chain. | Journal of microbiology and biotechnology 20080801 |
Characterization of a streptococcal cholesterol-dependent cytolysin with a lewis y and b specific lectin domain. | Biochemistry 20080708 |
Studies of Lewis antigens and H. pylori adhesion in CHO cell lines engineered to express Lewis b determinants. | Glycobiology 20080701 |
[Transfection of alpha1, 2-fucosyltransferase gene increases the antigenic expression of Lewis y in ovarian cancer cell line RMG-I]. | Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae 20080601 |
Analysis of Helicobacter pylori isolates from Chile: occurrence of selective type 1 Lewis b antigen expression in lipopolysaccharide. | Journal of medical microbiology 20080501 |
DC-SIGN mediates adhesion and rolling of dendritic cells on primary human umbilical vein endothelial cells through LewisY antigen expressed on ICAM-2. | Molecular immunology 20080401 |
Involvement of alpha 1-2-fucosyltransferase I (FUT1) and surface-expressed Lewis(y) (CD174) in first endothelial cell-cell contacts during angiogenesis. | Journal of cellular physiology 20080401 |
Suppression of FUT1/FUT4 expression by siRNA inhibits tumor growth. | Biochimica et biophysica acta 20080201 |
Expression of bisecting type and Lewisx/Lewisy terminated N-glycans on human sperm. | The Journal of biological chemistry 20071214 |
Targeting Lewis Y (Le(y)) in small cell lung cancer with a humanized monoclonal antibody, hu3S193: a pilot trial testing two dose levels. | Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 20071001 |
Radioimmunotherapy with alpha-particle emitting 213Bi-C-functionalized trans-cyclohexyl-diethylenetriaminepentaacetic acid-humanized 3S193 is enhanced by combination with paclitaxel chemotherapy. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070915 |
Expression of the blood-group-related antigens Sialyl Lewis a, Sialyl Lewis x and Lewis y in term placentas of normal, preeclampsia, IUGR- and HELLP-complicated pregnancies. | Histochemistry and cell biology 20070701 |
Analysis of lysine clipping of a humanized Lewis-Y specific IgG antibody and its relation to Fc-mediated effector function. | Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20070601 |
A phase I biodistribution and pharmacokinetic trial of humanized monoclonal antibody Hu3s193 in patients with advanced epithelial cancers that express the Lewis-Y antigen. | Clinical cancer research : an official journal of the American Association for Cancer Research 20070601 |
Virus-induced transcriptional activation of host FUT genes associated with neo-expression of Ley in cytomegalovirus-infected and sialyl-Lex in varicella-zoster virus-infected diploid human cells. | Glycobiology 20070401 |
A monoclonal antibody to Lewis Y/Lewis b revealing mimicry of the histone H1 to carbohydrate structures. | Scandinavian journal of immunology 20070401 |
Adhesion of Candida albicans to HeLa cells: studies using polystyrene beads. | Biological & pharmaceutical bulletin 20070301 |
Preparation of multifunctional glyconanoparticles as a platform for potential carbohydrate-based anticancer vaccines. | Carbohydrate research 20070226 |
Overexpression of fucosyltransferase IV in A431 cell line increases cell proliferation. | The international journal of biochemistry & cell biology 20070101 |
Expression of the carbohydrate tumour marker SLeX, SLeA (CA19-9), LeY and Thomsen-Friedenreich (TF) antigen on normal squamous epithelial tissue of the penis and vagina. | Anticancer research 20070101 |
Lewis(y) antigen (CD174) and apoptosis in gastric and colorectal carcinomas: correlations with clinical and prognostic parameters. | Histology and histopathology 20060501 |
[Genetic diagnosis of H. pylori infection]. | Nihon rinsho. Japanese journal of clinical medicine 20051201 |
Enhanced efficacy of radioimmunotherapy with 90Y-CHX-A''-DTPA-hu3S193 by inhibition of epidermal growth factor receptor (EGFR) signaling with EGFR tyrosine kinase inhibitor AG1478. | Clinical cancer research : an official journal of the American Association for Cancer Research 20051001 |
Synthesis of selected LeY and KH-1 analogues: a medicinal chemistry approach to vaccine optimization. | The Journal of organic chemistry 20050429 |
Clinical evaluation of BR96 sFv-PE40 immunotoxin therapy in canine models of spontaneously occurring invasive carcinoma. | Clinical cancer research : an official journal of the American Association for Cancer Research 20050115 |
A single-step method for the production of sugar hydrazides: intermediates for the chemoselective preparation of glycoconjugates. | Bioconjugate chemistry 20050101 |
High expression of Lewis y/b antigens is associated with decreased survival in lymph node negative breast carcinomas. | Breast cancer research : BCR 20050101 |
The immunogenicity of the tumor-associated antigen Lewis(y) may be suppressed by a bifunctional cross-linker required for coupling to a carrier protein. | Chemistry (Weinheim an der Bergstrasse, Germany) 20040719 |
Lectin receptors for endometrial H-type 1 antigen on goat conceptuses. | American journal of reproductive immunology (New York, N.Y. : 1989) 20040701 |
Antibody-targeted chemotherapy with the calicheamicin conjugate hu3S193-N-acetyl gamma calicheamicin dimethyl hydrazide targets Lewisy and eliminates Lewisy-positive human carcinoma cells and xenografts. | Clinical cancer research : an official journal of the American Association for Cancer Research 20040701 |
Expression of cell surface Lewis X and Y antigens and FUT4 mRNA is increased in Jurkat cells undergoing apoptosis. | Biochimica et biophysica acta 20040611 |
Kaposiform hemangioendothelioma: a study of 33 cases emphasizing its pathologic, immunophenotypic, and biologic uniqueness from juvenile hemangioma. | The American journal of surgical pathology 20040501 |
Killing of target cells by redirected granzyme B in the absence of perforin. | FEBS letters 20040326 |
Antibodies directed against Lewis-Y antigen inhibit signaling of Lewis-Y modified ErbB receptors. | Cancer research 20040201 |
Lewis antigen expression in gastric mucosa of children: relationship with Helicobacter pylori infection. | Journal of pediatric gastroenterology and nutrition 20040101 |
Host gastric Lewis expression determines the bacterial density of Helicobacter pylori in babA2 genopositive infection. | Gut 20030701 |
Expression of glycolipids bearing Lewis phenotypes in tissues and cultured cells of human gynecological cancers. | Japanese journal of cancer research : Gann 20021001 |
The expression of free oligosaccharides in human seminal plasma. | The Journal of biological chemistry 20020906 |
Constructing an adenocarcinoma vaccine: immunization of mice with synthetic KH-1 nonasaccharide stimulates anti-KH-1 and anti-Le(y) antibodies. | International journal of cancer 20020510 |
[Effects of Lewis Y oligosaccharide on secretion and gene expression of EGF and EGF-R in mouse embryos]. | Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica 20020501 |
Phenotypic variation in molecular mimicry between Helicobacter pylori lipopolysaccharides and human gastric epithelial cell surface glycoforms. Acid-induced phase variation in Lewis(x) and Lewis(y) expression by H. Pylori lipopolysaccharides. | The Journal of biological chemistry 20020222 |
Cathepsin B-labile dipeptide linkers for lysosomal release of doxorubicin from internalizing immunoconjugates: model studies of enzymatic drug release and antigen-specific in vitro anticancer activity. | Bioconjugate chemistry 20020101 |
Congenital nonprogressive hemangioma: a distinct clinicopathologic entity unlike infantile hemangioma. | Archives of dermatology 20011201 |
Ley glycolipid-recognizing monoclonal antibody inhibits procoagulant activity and metastasis of human adenocarcinoma. | International journal of oncology 20011101 |
Polymorphisms of two fucosyltransferase genes (Lewis and Secretor genes) involving type I Lewis antigens are associated with the presence of anti-Helicobacter pylori IgG antibody. | Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20010901 |
Increased expression of the blood group-related Lewis Y antigen on synovial fluid granulocytes of patients with arthritic joint diseases. | Rheumatology (Oxford, England) 20010901 |
Selective tumor sensitization to taxanes with the mAb-drug conjugate cBR96-doxorubicin. | International journal of cancer 20010815 |
Lewis antigen expression by Helicobacter pylori. | The Journal of infectious diseases 20010801 |
The fucosylated histo-blood group antigens H type 2 (blood group O, CD173) and Lewis Y (CD174) are expressed on CD34+ hematopoietic progenitors but absent on mature lymphocytes. | Glycobiology 20010801 |
Construction, expression and characterisation of a single-chain diabody derived from a humanised anti-Lewis Y cancer targeting antibody using a heat-inducible bacterial secretion vector. | Cancer immunology, immunotherapy : CII 20010701 |
Regulation of differentiation- and proliferation-inducers on Lewis antigens, alpha-fucosyltransferase and metastatic potential in hepatocarcinoma cells. | British journal of cancer 20010601 |
A unique microvascular phenotype shared by juvenile hemangiomas and human placenta. | Archives of dermatology 20010501 |
A comparison of Lewis x and Lewis y expression in Helicobacter pylori obtained from children and adults. | The Journal of infectious diseases 20010401 |
Biodistribution properties of (111)indium-labeled C-functionalized trans-cyclohexyl diethylenetriaminepentaacetic acid humanized 3S193 diabody and F(ab')(2) constructs in a breast carcinoma xenograft model. | Clinical cancer research : an official journal of the American Association for Cancer Research 20010401 |
Pursuit of optimal carbohydrate-based anticancer vaccines: preparation of a multiantigenic unimolecular glycopeptide containing the Tn, MBr1, and Lewis(y) antigens. | Journal of the American Chemical Society 20010307 |
Influence of cytokines, monoclonal antibodies and chemotherapeutic drugs on epithelial cell adhesion molecule (EpCAM) and LewisY antigen expression. | Clinical and experimental immunology 20010101 |
Schistosoma mansoni cercarial glycolipids are dominated by Lewis X and pseudo-Lewis Y structures. | Glycobiology 20000101 |
Are autoantibodies against Lewis antigens involved in the pathogenesis of Helicobacter pylori-induced peptic ulcers? | Microbiology and immunology 19990101 |
Lack of correlation between Lewis antigen expression by Helicobacter pylori and gastric epithelial cells in infected patients. | Gastroenterology 19981101 |
Expression of alpha-1,3-galactose and other type 2 oligosaccharide structures in a porcine endothelial cell line transfected with human alpha-1,2-fucosyltransferase cDNA. | The Journal of biological chemistry 19970912 |
The x-ray structure of an anti-tumour antibody in complex with antigen. | Nature structural biology 19950601 |