MLN-120B
| Title | Journal |
|---|---|
| Identification of potent Yes1 kinase inhibitors using a library screening approach. | Bioorganic & medicinal chemistry letters 20130801 |
| Comprehensive analysis of kinase inhibitor selectivity. | Nature biotechnology 20111030 |
| Activation state-dependent binding of small molecule kinase inhibitors: structural insights from biochemistry. | Chemistry & biology 20101124 |
| Activation of NF-kappaB signaling by inhibitor of NF-kappaB kinase beta increases aggressiveness of ovarian cancer. | Cancer research 20100515 |
| Inhibition of IKK-beta: a new development in the mechanism of the anti-obesity effects of PTP1B inhibitors SA18 and SA32. | Bioorganic & medicinal chemistry letters 20100201 |
| Nitric oxide inhibits IFN regulatory factor 1 and nuclear factor-kappaB pathways in rhinovirus-infected epithelial cells. | The Journal of allergy and clinical immunology 20090901 |
| Repression of inflammatory gene expression in human pulmonary epithelial cells by small-molecule IkappaB kinase inhibitors. | The Journal of pharmacology and experimental therapeutics 20070501 |
| Use of molecular imaging to quantify response to IKK-2 inhibitor treatment in murine arthritis. | Arthritis and rheumatism 20070101 |
| IKKbeta inhibition protects against bone and cartilage destruction in a rat model of rheumatoid arthritis. | Arthritis and rheumatism 20061001 |
| Validation of the anti-inflammatory properties of small-molecule IkappaB Kinase (IKK)-2 inhibitors by comparison with adenoviral-mediated delivery of dominant-negative IKK1 and IKK2 in human airways smooth muscle. | Molecular pharmacology 20060801 |
| Rapid TNFR1-dependent lymphocyte depletion in vivo with a selective chemical inhibitor of IKKbeta. | Blood 20060601 |
| A selective small molecule IkappaB Kinase beta inhibitor blocks nuclear factor kappaB-mediated inflammatory responses in human fibroblast-like synoviocytes, chondrocytes, and mast cells. | The Journal of pharmacology and experimental therapeutics 20060601 |