Ingenol Mebutate
| Title | Journal |
|---|---|
| Topical therapies for periorbital cutaneous malignancies: indications and treatment regimens. | Current opinion in ophthalmology 20120901 |
| Ingenol mebutate gel for actinic keratosis. | The New England journal of medicine 20120315 |
| Ivacaftor, vismodegib, and ingenol mebutate. | Journal of the American Pharmacists Association : JAPhA 20120101 |
| What's new in the treatment of actinic keratoses? | Cutis 20110201 |
| Topical antineoplastic agents in the treatment of mucocutaneous diseases. | Current problems in dermatology 20110101 |
| Novel antileukemic compound ingenol 3-angelate inhibits T cell apoptosis by activating protein kinase Ctheta. | The Journal of biological chemistry 20100730 |
| The skin cancer chemotherapeutic agent ingenol-3-angelate (PEP005) is a substrate for the epidermal multidrug transporter (ABCB1) and targets tumor vasculature. | Cancer research 20100601 |
| Primary human acute myelogenous leukemia cells release matrix metalloproteases and their inhibitors: release profile and pharmacological modulation. | European journal of haematology 20100301 |
| Epithelial-to-mesenchymal transition and resistance to ingenol 3-angelate, a novel protein kinase C modulator, in colon cancer cells. | Cancer research 20090515 |
| PEP005 (ingenol mebutate) gel, a novel agent for the treatment of actinic keratosis: results of a randomized, double-blind, vehicle-controlled, multicentre, phase IIa study. | The Australasian journal of dermatology 20090201 |
| Antiproliferative activity of PEP005, a novel ingenol angelate that modulates PKC functions, alone and in combination with cytotoxic agents in human colon cancer cells. | British journal of cancer 20081202 |
| Neutrophils are a key component of the antitumor efficacy of topical chemotherapy with ingenol-3-angelate. | Journal of immunology (Baltimore, Md. : 1950) 20061201 |
| Induction of senescence in diterpene ester-treated melanoma cells via protein kinase C-dependent hyperactivation of the mitogen-activated protein kinase pathway. | Cancer research 20061015 |
| HIV type 1 inhibition by protein kinase C modulatory compounds. | AIDS research and human retroviruses 20060901 |
| PEP005, a selective small-molecule activator of protein kinase C, has potent antileukemic activity mediated via the delta isoform of PKC. | Blood 20050815 |
| Ingenol 3-angelate induces dual modes of cell death and differentially regulates tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in melanoma cells. | Molecular cancer therapeutics 20041201 |
| Characterization of the interaction of ingenol 3-angelate with protein kinase C. | Cancer research 20040501 |
| Antitumor activity of 3-ingenyl angelate: plasma membrane and mitochondrial disruption and necrotic cell death. | Cancer research 20040415 |