sales@angenesci.com
Login | Register
logo
Structures Search
Home Other Building Blocks AKT Kinase Inhibitor

AKT Kinase Inhibitor

CAS No.:
842148-40-7
Catalog Number:
AG00G3NC
Molecular Formula:
C16H19N7O3
Molecular Weight:
357.3672
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
5mg
98%
1 week
United States
$640
- +
10mg
98%
1 week
United States
$1057
- +
Product Description
Catalog Number:
AG00G3NC
Chemical Name:
AKT Kinase Inhibitor
CAS Number:
842148-40-7
Molecular Formula:
C16H19N7O3
Molecular Weight:
357.3672
MDL Number:
MFCD18642579
IUPAC Name:
3-[2-(4-amino-1,2,5-oxadiazol-3-yl)-7-(3-aminopropoxy)-1-ethylimidazo[4,5-c]pyridin-4-yl]prop-2-yn-1-ol
InChI:
InChI=1S/C16H19N7O3/c1-2-23-14-11(25-8-4-6-17)9-19-10(5-3-7-24)12(14)20-16(23)13-15(18)22-26-21-13/h9,24H,2,4,6-8,17H2,1H3,(H2,18,22)
InChI Key:
LWLOLQIXHMFYND-UHFFFAOYSA-N
SMILES:
NCCCOc1cnc(c2c1n(CC)c(n2)c1nonc1N)C#CCO
Properties
Complexity:
525  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
0
Defined Bond Stereocenter Count:
0
Exact Mass:
357.155g/mol
Formal Charge:
0
Heavy Atom Count:
26  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
357.374g/mol
Monoisotopic Mass:
357.155g/mol
Rotatable Bond Count:
7  
Topological Polar Surface Area:
151A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
-1.2  
Literature
Title Journal
Identification of 4-(2-(4-amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-{[(3S)-3-piperidinylmethyl]oxy}-1H-imidazo[4,5-c]pyridin-4-yl)-2-methyl-3-butyn-2-ol (GSK690693), a novel inhibitor of AKT kinase. Journal of medicinal chemistry 20080925
Properties