(3S)-3-[3-(4-Fluorophenyl)-1,2,4-oxadiazol-5-yl]-1-[(4-fluorophenyl)carbonyl]piperidine
| Title | Journal |
|---|---|
| In vitro characterisation of the novel positive allosteric modulators of the mGlu₅ receptor, LSN2463359 and LSN2814617, and their effects on sleep architecture and operant responding in the rat. | Neuropharmacology 20130101 |
| mGlu5 Receptor Functional Interactions and Addiction. | Frontiers in pharmacology 20120101 |
| On the Role of Cannabinoid CB1- and μ-Opioid Receptors in Motor Impulsivity. | Frontiers in pharmacology 20120101 |
| Differential effect of the mGlu5 receptor positive allosteric modulator ADX-47273 on early and late hippocampal LTP. | Neuropharmacology 20110901 |
| Discovery of molecular switches within the ADX-47273 mGlu5 PAM scaffold that modulate modes of pharmacology to afford potent mGlu5 NAMs, PAMs and partial antagonists. | Bioorganic & medicinal chemistry letters 20110501 |
| Differential Modulation of Thresholds for Intracranial Self-Stimulation by mGlu5 Positive and Negative Allosteric Modulators: Implications for Effects on Drug Self-Administration. | Frontiers in pharmacology 20110101 |
| Beyond the dopamine receptor: novel therapeutic targets for treating schizophrenia. | Dialogues in clinical neuroscience 20100901 |
| Functional interaction of metabotropic glutamate receptor 5 and NMDA-receptor by a metabotropic glutamate receptor 5 positive allosteric modulator. | European journal of pharmacology 20100810 |
| Effects of a positive allosteric modulator of mGluR5 ADX47273 on conditioned avoidance response and PCP-induced hyperlocomotion in the rat as models for schizophrenia. | Pharmacology, biochemistry, and behavior 20100301 |
| Metabotropic glutamate receptors: potential drug targets for psychiatric disorders. | The open medicinal chemistry journal 20100101 |
| Effects of positive allosteric modulators on single-cell oscillatory Ca2+ signaling initiated by the type 5 metabotropic glutamate receptor. | Molecular pharmacology 20091201 |
| Comparison of the mGlu(5) receptor positive allosteric modulator ADX47273 and the mGlu(2/3) receptor agonist LY354740 in tests for antipsychotic-like activity. | European journal of pharmacology 20091125 |
| Synthesis, SAR and unanticipated pharmacological profiles of analogues of the mGluR5 ago-potentiator ADX-47273. | ChemMedChem 20090401 |
| ADX47273 [S-(4-fluoro-phenyl)-{3-[3-(4-fluoro-phenyl)-[1,2,4]-oxadiazol-5-yl]-piperidin-1-yl}-methanone]: a novel metabotropic glutamate receptor 5-selective positive allosteric modulator with preclinical antipsychotic-like and procognitive activities. | The Journal of pharmacology and experimental therapeutics 20081201 |
| Substituent effects of N-(1,3-diphenyl-1H-pyrazol-5-yl)benzamides on positive allosteric modulation of the metabotropic glutamate-5 receptor in rat cortical astrocytes. | Journal of medicinal chemistry 20060601 |