Home Other Building Blocks Ganoderic acid A

Ganoderic acid A

CAS No.:
81907-62-2
Catalog Number:
AG00G35W
Molecular Formula:
C30H44O7
Molecular Weight:
516.6662
Pack Size
Purity
Availability
Location
Price(USD)
Quantity
  
1mg
99%
1 week
United States
$190
- +
5mg
99%
1 week
United States
$357
- +
10mg
99%
1 week
United States
$440
- +
25mg
99%
1 week
United States
$890
- +
Product Description
Catalog Number:
AG00G35W
Chemical Name:
Ganoderic acid A
CAS Number:
81907-62-2
Molecular Formula:
C30H44O7
Molecular Weight:
516.6662
MDL Number:
MFCD26131275
IUPAC Name:
(2R,6R)-6-[(5R,7S,10S,13R,14R,15S,17R)-7,15-dihydroxy-4,4,10,13,14-pentamethyl-3,11-dioxo-2,5,6,7,12,15,16,17-octahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-methyl-4-oxoheptanoic acid
InChI:
InChI=1S/C30H44O7/c1-15(10-17(31)11-16(2)26(36)37)18-12-23(35)30(7)25-19(32)13-21-27(3,4)22(34)8-9-28(21,5)24(25)20(33)14-29(18,30)6/h15-16,18-19,21,23,32,35H,8-14H2,1-7H3,(H,36,37)/t15-,16-,18-,19+,21+,23+,28+,29-,30+/m1/s1
InChI Key:
DYOKDAQBNHPJFD-JNTBEZBXSA-N
SMILES:
O=C(C[C@H](C(=O)O)C)C[C@H]([C@H]1C[C@@H]([C@@]2([C@]1(C)CC(=O)C1=C2[C@@H](O)CC2[C@]1(C)CCC(=O)C2(C)C)C)O)C
UNII:
548G37DF65
Properties
Complexity:
1070  
Compound Is Canonicalized:
Yes
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
9  
Defined Bond Stereocenter Count:
0
Exact Mass:
516.309g/mol
Formal Charge:
0
Heavy Atom Count:
37  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
3  
Isotope Atom Count:
0
Molecular Weight:
516.675g/mol
Monoisotopic Mass:
516.309g/mol
Rotatable Bond Count:
6  
Topological Polar Surface Area:
129A^2
Undefined Atom Stereocenter Count:
0
Undefined Bond Stereocenter Count:
0
XLogP3:
2.2  
Literature
Title Journal
Ganoderic Acid A improves high fat diet-induced obesity, lipid accumulation and insulin sensitivity through regulating SREBP pathway. Chemico-biological interactions 20180625
Structure-activity relationships of ganoderma acids from Ganoderma lucidum as aldose reductase inhibitors. Bioorganic & medicinal chemistry letters 20111215
Sensitive and selective liquid chromatography-tandem mass spectrometry method for the determination of five ganoderic acids in Ganoderma lucidum and its related species. Journal of pharmaceutical and biomedical analysis 20110325
Inhibition of aldose reductase in vitro by constituents of Ganoderma lucidum. Planta medica 20101001
Lanostane triterpenes from the fruiting bodies of Ganoderma lucidum and their inhibitory effects on adipocyte differentiation in 3T3-L1 Cells. Journal of natural products 20100226
11beta-Hydroxysteroid dehydrogenase 1 inhibiting constituents from Eriobotrya japonica revealed by bioactivity-guided isolation and computational approaches. Bioorganic & medicinal chemistry 20100215
Development of a new method for improved identification and relative quantification of unknown metabolites in complex samples: determination of a triterpenoid metabolic fingerprint for the in situ characterization of Ganoderma bioactive compounds. Journal of separation science 20091201
Metabolism and pharmacokinetics in rats of ganoderiol F, a highly cytotoxic and antitumor triterpene from Ganoderma lucidum. Journal of natural medicines 20090701
Performance analyses of a pH-shift and DOT-shift integrated fed-batch fermentation process for the production of ganoderic acid and Ganoderma polysaccharides by medicinal mushroom Ganoderma lucidum. Bioresource technology 20090301
Ganoderic acids suppress growth and invasive behavior of breast cancer cells by modulating AP-1 and NF-kappaB signaling. International journal of molecular medicine 20080501
[Chemical constituents of the spores of Ganoderma lucidum]. Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials 20080101
Inhibition of oxidative stress-induced invasiveness of cancer cells by Ganoderma lucidum is mediated through the suppression of interleukin-8 secretion. International journal of molecular medicine 20061001
Anti-HIV-1 and anti-HIV-1-protease substances from Ganoderma lucidum. Phytochemistry 19981101
Triterpenes from the spores of Ganoderma lucidum and their inhibitory activity against HIV-1 protease. Chemical & pharmaceutical bulletin 19981001
Properties